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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117458000
log Bayes Factor = 12.1666
Chromosome 16   position 79,776,544  (GRCh37) Explore rs117458000 on Ensembl!
Variant rs117458000 is part of Cluster X0068

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.997 0.003 0.000
Z85 Personal history of malignant neoplasm
0.996 0.004 0.000
M20-M25 Other joint disorders
0.995 0.005 0.000
Chapter V Mental and behavioural disorders
0.993 0.007 0.000
Chapter II Neoplasms
0.992 0.008 0.000
K70-K77 Diseases of liver
0.991 0.009 0.000
Chapter X Diseases of the respiratory system
0.985 0.015 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.985 0.015 0.000
J30-J39 Other diseases of upper respiratory tract
0.984 0.016 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.984 0.016 0.000
Chapter XIV Diseases of the genitourinary system
0.983 0.017 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.981 0.019 0.000
Z88.0 Personal history of allergy to penicillin
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.977 0.023 0.000
C50-C50 Malignant neoplasm of breast
0.976 0.024 0.000
Z92 Personal history of medical treatment
0.975 0.025 0.000
F41 Other anxiety disorders
0.975 0.025 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.972 0.028 0.000
K70 Alcoholic liver disease
0.971 0.029 0.000
M25 Other joint disorders, not elsewhere classified
0.967 0.033 0.000
F41.2 Mixed anxiety and depressive disorder
0.966 0.034 0.000
M13 Other arthritis
0.965 0.035 0.000
C50 Malignant neoplasm of breast
0.964 0.036 0.000
M20 Acquired deformities of fingers and toes
0.961 0.039 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.959 0.041 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.957 0.043 0.000
M13.9 Arthritis, unspecified
0.957 0.043 0.000
J34 Other disorders of nose and nasal sinuses
0.954 0.046 0.000
S70-S79 Injuries to the hip and thigh
0.952 0.048 0.000
S60-S69 Injuries to the wrist and hand
0.947 0.053 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.945 0.055 0.000
J33 Nasal polyp
0.944 0.056 0.000
K04 Diseases of pulp and periapical tissues
0.943 0.057 0.000
Z92.3 Personal history of irradiation
0.942 0.058 0.000
Z88.2 Personal history of allergy to sulphonamides
0.938 0.062 0.000
N25-N29 Other disorders of kidney and ureter
0.929 0.071 0.000
K70.9 Alcoholic liver disease, unspecified
0.928 0.072 0.000
Z88.5 Personal history of allergy to narcotic agent
0.928 0.072 0.000
K08 Other disorders of teeth and supporting structures
0.927 0.073 0.000
N60-N64 Disorders of breast
0.924 0.076 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.922 0.078 0.000
M25.5 Pain in joint
0.921 0.079 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.916 0.084 0.000
C50.9 Breast, unspecified
0.916 0.084 0.000
K04.7 Periapical abscess without sinus
0.912 0.088 0.000
M45-M49 Spondylopathies
0.912 0.088 0.000
S62 Fracture at wrist and hand level
0.912 0.088 0.000
S72 Fracture of femur
0.910 0.090 0.000
M13.94 Arthritis, unspecified (Hand)
0.909 0.091 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.907 0.093 0.000
N30-N39 Other diseases of urinary system
0.907 0.093 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.906 0.094 0.000
J33.0 Polyp of nasal cavity
0.905 0.095 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.898 0.102 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.898 0.102 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.898 0.102 0.000
M25.57 Pain in joint (Ankle and foot)
0.896 0.104 0.000
K08.3 Retained dental root
0.888 0.112 0.000
N20-N23 Urolithiasis
0.885 0.115 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.883 0.117 0.000
C50.2 Upper-inner quadrant of breast
0.883 0.117 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.880 0.120 0.000
J34.2 Deviated nasal septum
0.878 0.122 0.000
S72.0 Fracture of neck of femur
0.877 0.123 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.876 0.124 0.000
M20.4 Other hammer toe(s) (acquired)
0.876 0.124 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.873 0.127 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.872 0.128 0.000
C50.4 Upper-outer quadrant of breast
0.872 0.128 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.870 0.130 0.000
K74 Fibrosis and cirrhosis of liver
0.870 0.130 0.000
D00-D09 In situ neoplasms
0.868 0.132 0.000
M13.98 Arthritis, unspecified (Other)
0.867 0.133 0.000
J30 Vasomotor and allergic rhinitis
0.865 0.135 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.862 0.138 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.862 0.138 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.861 0.139 0.000
S62.6 Fracture of other finger
0.861 0.139 0.000
M86-M90 Other osteopathies
0.860 0.140 0.000
M07 Psoriatic and enteropathic arthropathies
0.859 0.141 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.858 0.142 0.000
M20.5 Other deformities of toe(s) (acquired)
0.856 0.144 0.000
S72.00 Fracture of neck of femur (closed)
0.853 0.147 0.000
N20 Calculus of kidney and ureter
0.851 0.149 0.000
C80 Malignant neoplasm without specification of site
0.851 0.149 0.000
N39 Other disorders of urinary system
0.848 0.152 0.000
K90-K93 Other diseases of the digestive system
0.848 0.152 0.000
N35 Urethral stricture
0.848 0.152 0.000
K65-K67 Diseases of peritoneum
0.847 0.153 0.000
M47 Spondylosis
0.843 0.156 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.839 0.161 0.000
Chapter VI Diseases of the nervous system
0.837 0.163 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.834 0.166 0.000
J84 Other interstitial pulmonary diseases
0.833 0.167 0.000
K13 Other diseases of lip and oral mucosa
0.831 0.169 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.830 0.170 0.000
K70.3 Alcoholic cirrhosis of liver
0.829 0.171 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.827 0.173 0.000
S20-S29 Injuries to the thorax
0.827 0.173 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.827 0.173 0.000
N39.3 Stress incontinence
0.827 0.173 0.000
Z98 Other postsurgical states
0.826 0.174 0.000
N64 Other disorders of breast
0.825 0.175 0.000
K75 Other inflammatory liver diseases
0.824 0.176 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.824 0.176 0.000
S62.60 Fracture of other finger (closed)
0.822 0.178 0.000
J33.9 Nasal polyp, unspecified
0.821 0.179 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.820 0.180 0.000
K04.6 Periapical abscess with sinus
0.819 0.181 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.817 0.183 0.000
C79 Secondary malignant neoplasm of other sites
0.817 0.183 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.816 0.184 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.816 0.184 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.815 0.185 0.000
M47.9 Spondylosis, unspecified
0.811 0.189 0.000
J39 Other diseases of upper respiratory tract
0.805 0.195 0.000
N35.9 Urethral stricture, unspecified
0.805 0.195 0.000
K74.6 Other and unspecified cirrhosis of liver
0.804 0.196 0.000
M22 Disorders of patella
0.804 0.196 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.802 0.198 0.000
Chapter I Certain infectious and parasitic diseases
0.801 0.199 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.799 0.201 0.000
M21 Other acquired deformities of limbs
0.798 0.202 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.797 0.203 0.000
M20.1 Hallux valgus (acquired)
0.796 0.204 0.000
N28.1 Cyst of kidney, acquired
0.794 0.206 0.000
J32 Chronic sinusitis
0.794 0.206 0.000
F30-F39 Mood [affective] disorders
0.793 0.207 0.000
M65-M68 Disorders of synovium and tendon
0.793 0.207 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.791 0.209 0.000
Z41 Procedures for purposes other than remedying health state
0.789 0.211 0.000
Z45 Adjustment and management of implanted device
0.789 0.211 0.000
J81 Pulmonary oedema
0.788 0.212 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.788 0.212 0.000
M15-M19 Arthrosis
0.787 0.213 0.000
S10-S19 Injuries to the neck
0.785 0.215 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.783 0.217 0.000
Z22 Carrier of infectious disease
0.783 0.217 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.782 0.217 0.000
K66 Other disorders of peritoneum
0.782 0.218 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.781 0.219 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.779 0.221 0.000
S64 Injury of nerves at wrist and hand level
0.778 0.222 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.778 0.222 0.000
F10.3 Withdrawal state
0.777 0.223 0.000
M07.3 Other psoriatic arthropathies
0.774 0.226 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.774 0.226 0.000
K76 Other diseases of liver
0.773 0.227 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.772 0.228 0.000
Z29 Need for other prophylactic measures
0.771 0.229 0.000
K70.0 Alcoholic fatty liver
0.771 0.229 0.000
Z47 Other orthopaedic follow-up care
0.771 0.229 0.000
C50.8 Overlapping lesion of breast
0.770 0.230 0.000
K01 Embedded and impacted teeth
0.768 0.232 0.000
Z60 Problems related to social environment
0.767 0.233 0.000
M25.51 Pain in joint (Shoulder region)
0.767 0.233 0.000
G90-G99 Other disorders of the nervous system
0.767 0.233 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.767 0.233 0.000
Z92.0 Personal history of contraception
0.762 0.238 0.000
N60 Benign mammary dysplasia
0.761 0.239 0.000
F42 Obsessive-compulsive disorder
0.760 0.239 0.000
N30 Cystitis
0.760 0.240 0.000
F45 Somatoform disorders
0.759 0.241 0.000
M60-M63 Disorders of muscles
0.759 0.241 0.000
C64-C68 Malignant neoplasms of urinary tract
0.759 0.241 0.000
T79-T79 Certain early complications of trauma
0.758 0.241 0.000
N20.0 Calculus of kidney
0.758 0.242 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.757 0.243 0.000
T66-T78 Other and unspecified effects of external causes
0.754 0.246 0.000
N62 Hypertrophy of breast
0.754 0.246 0.000
F40 Phobic anxiety disorders
0.754 0.246 0.000
M25.3 Other instability of joint
0.752 0.248 0.000
N39.4 Other specified urinary incontinence
0.751 0.249 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.750 0.250 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.750 0.250 0.000
M20.2 Hallux rigidus
0.749 0.251 0.000
C78.0 Secondary malignant neoplasm of lung
0.749 0.251 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.749 0.251 0.000
N64.9 Disorder of breast, unspecified
0.748 0.252 0.000
M34 Systemic sclerosis
0.748 0.252 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.747 0.253 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.745 0.255 0.000
C80.9 Malignant neoplasm, unspecified
0.744 0.256 0.000
M25.7 Osteophyte
0.744 0.256 0.000
S62.8 Fracture of other and unspecified parts of wrist and hand
0.744 0.256 0.000
T92 Sequelae of injuries of upper limb
0.742 0.258 0.000
Chapter VII Diseases of the eye and adnexa
0.742 0.258 0.000
S72.2 Subtrochanteric fracture
0.741 0.259 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.740 0.260 0.000
F60-F69 Disorders of adult personality and behaviour
0.739 0.261 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.739 0.261 0.000
M25.54 Pain in joint (Hand)
0.739 0.261 0.000
M19 Other arthrosis
0.739 0.261 0.000
K31 Other diseases of stomach and duodenum
0.738 0.262 0.000
Chapter XX External causes of morbidity and mortality
0.738 0.262 0.000
S69 Other and unspecified injuries of wrist and hand
0.738 0.262 0.000
Z98.0 Intestinal bypass and anastomosis status
0.738 0.262 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.736 0.263 0.000
K66.0 Peritoneal adhesions
0.736 0.264 0.000
J30.4 Allergic rhinitis, unspecified
0.735 0.265 0.000
C50.3 Lower-inner quadrant of breast
0.734 0.266 0.000
M91-M94 Chondropathies
0.734 0.266 0.000
Z81 Family history of mental and behavioural disorders
0.733 0.267 0.000
S79 Other and unspecified injuries of hip and thigh
0.732 0.267 0.000
F99-F99 Unspecified mental disorder
0.732 0.268 0.000
Z89 Acquired absence of limb
0.732 0.268 0.000
M00-M03 Infectious arthropathies
0.732 0.268 0.000
N20.2 Calculus of kidney with calculus of ureter
0.729 0.271 0.000
N26 Unspecified contracted kidney
0.727 0.273 0.000
Z88.6 Personal history of allergy to analgesic agent
0.727 0.273 0.000
N20.9 Urinary calculus, unspecified
0.726 0.274 0.000
J37 Chronic laryngitis and laryngotracheitis
0.726 0.274 0.000
S90-S99 Injuries to the ankle and foot
0.726 0.274 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.725 0.275 0.000
Z99.8 Dependence on other enabling machines and devices
0.722 0.278 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.721 0.279 0.000
Z50 Care involving use of rehabilitation procedures
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.718 0.282 0.000
M25.4 Effusion of joint
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T91 Sequelae of injuries of neck and trunk
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
M25.0 Haemarthrosis
0.717 0.283 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.716 0.284 0.000
K70.4 Alcoholic hepatic failure
0.716 0.284 0.000
M23 Internal derangement of knee
0.715 0.285 0.000
K14 Diseases of tongue
0.715 0.285 0.000
F10.2 Dependence syndrome
0.715 0.285 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.715 0.285 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.714 0.286 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.713 0.286 0.000
M33 Dermatopolymyositis
0.713 0.286 0.000
M32 Systemic lupus erythematosus
0.713 0.286 0.000
M30 Polyarteritis nodosa and related conditions
0.713 0.286 0.000
K50-K52 Noninfective enteritis and colitis
0.713 0.287 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.712 0.288 0.000
F70-F79 Mental retardation
0.712 0.288 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.711 0.288 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.711 0.288 0.000
D06 Carcinoma in situ of cervix uteri
0.711 0.289 0.000
K77 Liver disorders in diseases classified elsewhere
0.711 0.289 0.000
K73 Chronic hepatitis, not elsewhere classified
0.711 0.289 0.000
K71 Toxic liver disease
0.711 0.289 0.000
F41.1 Generalised anxiety disorder
0.709 0.290 0.000
G93 Other disorders of brain
0.709 0.291 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.708 0.292 0.000
C60-C63 Malignant neoplasms of male genital organs
0.708 0.292 0.000
G70-G73 Diseases of myoneural junction and muscle
0.707 0.292 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.707 0.293 0.000
N40-N51 Diseases of male genital organs
0.706 0.294 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.706 0.294 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.706 0.294 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.706 0.294 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.706 0.294 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.706 0.294 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.706 0.294 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.706 0.294 0.000
T36 Poisoning by systemic antibiotics
0.706 0.294 0.000
Q60-Q64 Congenital malformations of the urinary system
0.706 0.294 0.000
F48 Other neurotic disorders
0.705 0.294 0.000
F44 Dissociative [conversion] disorders
0.705 0.294 0.000
M89 Other disorders of bone
0.705 0.295 0.000
Chapter XXII Codes for special purposes
0.704 0.296 0.000
K03 Other diseases of hard tissues of teeth
0.703 0.297 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.703 0.297 0.000
M18 Arthrosis of first carpometacarpal joint
0.702 0.298 0.000
M46 Other inflammatory spondylopathies
0.702 0.298 0.000
K70.1 Alcoholic hepatitis
0.701 0.298 0.000
M13.0 Polyarthritis, unspecified
0.701 0.298 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.700 0.299 0.000
K72 Hepatic failure, not elsewhere classified
0.700 0.300 0.000
M14 Arthropathies in other diseases classified elsewhere
0.700 0.300 0.000
M12 Other specific arthropathies
0.700 0.300 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.700 0.300 0.000
M08 Juvenile arthritis
0.700 0.300 0.000
M90 Osteopathies in diseases classified elsewhere
0.700 0.300 0.000
Z94 Transplanted organ and tissue status
0.700 0.300 0.000
Z92.9 Personal history of medical treatment, unspecified
0.699 0.301 0.000
Z92.8 Personal history of other medical treatment
0.699 0.301 0.000
Z92.5 Personal history of rehabilitation measures
0.699 0.301 0.000
F41.8 Other specified anxiety disorders
0.699 0.301 0.000
F41.3 Other mixed anxiety disorders
0.699 0.301 0.000
M25.8 Other specified joint disorders
0.699 0.301 0.000
G30-G32 Other degenerative diseases of the nervous system
0.699 0.301 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.699 0.301 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.699 0.301 0.000
Z63 Other problems related to primary support group, including family circumstances
0.698 0.302 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.698 0.302 0.000
D05 Carcinoma in situ of breast
0.697 0.303 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.696 0.304 0.000
K00 Disorders of tooth development and eruption
0.696 0.304 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.695 0.305 0.000
B15-B19 Viral hepatitis
0.694 0.306 0.000
M25.9 Joint disorder, unspecified
0.694 0.306 0.000
M25.2 Flail joint
0.694 0.306 0.000
M25.1 Fistula of joint
0.694 0.306 0.000
H40-H42 Glaucoma
0.694 0.306 0.000
T43.2 Other and unspecified antidepressants
0.693 0.306 0.000
T40.6 Other and unspecified narcotics
0.693 0.307 0.000
S62.3 Fracture of other metacarpal bone
0.693 0.307 0.000
M13.8 Other specified arthritis
0.692 0.308 0.000
M13.1 Monoarthritis, not elsewhere classified
0.692 0.308 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.692 0.308 0.000
A30-A49 Other bacterial diseases
0.692 0.308 0.000
C50.6 Axillary tail of breast
0.691 0.309 0.000
Z58 Problems related to physical environment
0.691 0.309 0.000
Z93 Artificial opening status
0.690 0.310 0.000
N63 Unspecified lump in breast
0.690 0.310 0.000
Z48 Other surgical follow-up care
0.689 0.311 0.000
C79.6 Secondary malignant neoplasm of ovary
0.688 0.312 0.000
D04 Carcinoma in situ of skin
0.688 0.312 0.000
S70 Superficial injury of hip and thigh
0.687 0.313 0.000
M24 Other specific joint derangements
0.687 0.313 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.686 0.313 0.000
Z45.2 Adjustment and management of vascular access device
0.686 0.314 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.686 0.314 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.686 0.314 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.685 0.314 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.685 0.315 0.000
K07 Dentofacial anomalies [including malocclusion]
0.685 0.315 0.000
T42.4 Benzodiazepines
0.685 0.315 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.684 0.316 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.684 0.316 0.000
T51 Toxic effect of alcohol
0.684 0.316 0.000
M65 Synovitis and tenosynovitis
0.683 0.317 0.000
S78 Traumatic amputation of hip and thigh
0.683 0.317 0.000
S77 Crushing injury of hip and thigh
0.683 0.317 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.683 0.317 0.000
S75 Injury of blood vessels at hip and thigh level
0.683 0.317 0.000
S74 Injury of nerves at hip and thigh level
0.683 0.317 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.683 0.317 0.000
S71 Open wound of hip and thigh
0.683 0.317 0.000
M07.39 Other psoriatic arthropathies (Site unspecified)
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.682 0.317 0.000
S62.0 Fracture of navicular [scaphoid] bone of hand
0.681 0.318 0.000
Z57 Occupational exposure to risk-factors
0.679 0.321 0.000
S65 Injury of blood vessels at wrist and hand level
0.679 0.321 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.678 0.322 0.000
Z47.0 Follow-up care involving removal of fracture plate and other internal fixation device
0.678 0.322 0.000
Z22.3 Carrier of other specified bacterial diseases
0.678 0.322 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.677 0.323 0.000
K10 Other diseases of jaws
0.677 0.323 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.677 0.323 0.000
J33.1 Polypoid sinus degeneration
0.677 0.323 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.676 0.324 0.000
K04.3 Abnormal hard tissue formation in pulp
0.676 0.324 0.000
K04.2 Pulp degeneration
0.676 0.324 0.000
K04.1 Necrosis of pulp
0.676 0.324 0.000
K04.0 Pulpitis
0.676 0.324 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.676 0.324 0.000
M31 Other necrotising vasculopathies
0.676 0.324 0.000
F32 Depressive episode
0.675 0.325 0.000
K13.7 Other and unspecified lesions of oral mucosa
0.674 0.326 0.000
Z60.2 Living alone
0.673 0.327 0.000
M13.93 Arthritis, unspecified (Forearm)
0.672 0.328 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.671 0.329 0.000
F10.0 Acute intoxication
0.671 0.329 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.671 0.329 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.671 0.329 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.671 0.329 0.000
M45 Ankylosing spondylitis
0.670 0.330 0.000
J38.7 Other diseases of larynx
0.670 0.330 0.000
J36 Peritonsillar abscess
0.670 0.330 0.000
S40-S49 Injuries to the shoulder and upper arm
0.670 0.330 0.000
K13.0 Diseases of lips
0.670 0.330 0.000
N28.0 Ischaemia and infarction of kidney
0.669 0.331 0.000
Chapter VIII Diseases of the ear and mastoid process
0.668 0.332 0.000
J30.3 Other allergic rhinitis
0.668 0.332 0.000
M22.4 Chondromalacia patellae
0.668 0.332 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.666 0.334 0.000
N27 Small kidney of unknown cause
0.666 0.334 0.000
N25 Disorders resulting from impaired renal tubular function
0.666 0.334 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.666 0.334 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.666 0.334 0.000
J80 Adult respiratory distress syndrome
0.666 0.334 0.000
J30.1 Allergic rhinitis due to pollen
0.665 0.335 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.665 0.335 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.665 0.335 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.662 0.338 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.662 0.338 0.000
C69 Malignant neoplasm of eye and adnexa
0.661 0.339 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.661 0.339 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.661 0.339 0.000
M25.58 Pain in joint (Other)
0.660 0.340 0.000
M25.52 Pain in joint (Upper arm)
0.660 0.340 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.660 0.340 0.000
N42 Other disorders of prostate
0.659 0.341 0.000
H40 Glaucoma
0.659 0.341 0.000
C71 Malignant neoplasm of brain
0.659 0.341 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.659 0.341 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.658 0.342 0.000
S60 Superficial injury of wrist and hand
0.657 0.343 0.000
S64.4 Injury of digital nerve of other finger
0.657 0.343 0.000
Z46 Fitting and adjustment of other devices
0.655 0.345 0.000
J32.0 Chronic maxillary sinusitis
0.655 0.345 0.000
N30.3 Trigonitis
0.655 0.345 0.000
N30.8 Other cystitis
0.655 0.345 0.000
N39.9 Disorder of urinary system, unspecified
0.654 0.346 0.000
Z45.8 Adjustment and management of other implanted devices
0.654 0.346 0.000
M25.59 Pain in joint (Site unspecified)
0.654 0.346 0.000
S67 Crushing injury of wrist and hand
0.654 0.346 0.000
M49 Spondylopathies in diseases classified elsewhere
0.654 0.346 0.000
S62.7 Multiple fractures of fingers
0.654 0.346 0.000
S62.5 Fracture of thumb
0.654 0.346 0.000
S62.4 Multiple fractures of metacarpal bones
0.654 0.346 0.000
S62.2 Fracture of first metacarpal bone
0.654 0.346 0.000
S62.1 Fracture of other carpal bone(s)
0.654 0.346 0.000
K91.4 Colostomy and enterostomy malfunction
0.654 0.346 0.000
S72.9 Fracture of femur, part unspecified
0.653 0.347 0.000
S72.8 Fractures of other parts of femur
0.653 0.347 0.000
S72.7 Multiple fractures of femur
0.653 0.347 0.000
S72.4 Fracture of lower end of femur
0.653 0.347 0.000
M19.9 Arthrosis, unspecified
0.653 0.347 0.000
T98 Sequelae of other and unspecified effects of external causes
0.652 0.347 0.000
D03 Melanoma in situ
0.652 0.348 0.000
Z28 Immunisation not carried out
0.650 0.349 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.650 0.349 0.000
Z26 Need for immunisation against other single infectious diseases
0.650 0.349 0.000
Z25 Need for immunisation against other single viral diseases
0.650 0.349 0.000
Z24 Need for immunisation against certain single viral diseases
0.650 0.349 0.000
Z23 Need for immunisation against single bacterial diseases
0.650 0.349 0.000
Z20 Contact with and exposure to communicable diseases
0.650 0.349 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.650 0.349 0.000
K75.4 Autoimmune hepatitis
0.650 0.350 0.000
N37 Urethral disorders in diseases classified elsewhere
0.650 0.350 0.000
N34 Urethritis and urethral syndrome
0.650 0.350 0.000
N33 Bladder disorders in diseases classified elsewhere
0.650 0.350 0.000
J39.2 Other diseases of pharynx
0.649 0.351 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.648 0.352 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.648 0.352 0.000
D09 Carcinoma in situ of other and unspecified sites
0.647 0.353 0.000
N10-N16 Renal tubulo-interstitial diseases
0.647 0.353 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.647 0.353 0.000
K22 Other diseases of oesophagus
0.646 0.354 0.000
Q80-Q89 Other congenital malformations
0.646 0.354 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.646 0.354 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.645 0.355 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.645 0.355 0.000
C50.0 Nipple and areola
0.645 0.355 0.000
Z65 Problems related to other psychosocial circumstances
0.644 0.356 0.000
Z64 Problems related to certain psychosocial circumstances
0.644 0.356 0.000
Z62 Other problems related to upbringing
0.644 0.356 0.000
Z61 Problems related to negative life events in childhood
0.644 0.356 0.000
Z59 Problems related to housing and economic circumstances
0.644 0.356 0.000
Z56 Problems related to employment and unemployment
0.644 0.356 0.000
Z55 Problems related to education and literacy
0.644 0.356 0.000
N00-N08 Glomerular diseases
0.644 0.356 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.644 0.356 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.644 0.356 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.644 0.356 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.644 0.356 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.644 0.356 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.644 0.356 0.000
F11 Mental and behavioural disorders due to use of opioids
0.644 0.356 0.000
Z50.2 Alcohol rehabilitation
0.644 0.356 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.644 0.356 0.000
M25.76 Osteophyte (Lower leg)
0.644 0.356 0.000
K05 Gingivitis and periodontal diseases
0.643 0.356 0.000
Z29.1 Prophylactic immunotherapy
0.642 0.358 0.000
N99-N99 Other disorders of the genitourinary system
0.641 0.359 0.000
J38.4 Oedema of larynx
0.641 0.359 0.000
N75 Diseases of Bartholin's gland
0.641 0.359 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.641 0.359 0.000
M25.53 Pain in joint (Forearm)
0.641 0.359 0.000
S00-S09 Injuries to the head
0.640 0.360 0.000
Q00-Q07 Congenital malformations of the nervous system
0.639 0.361 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.639 0.361 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.639 0.361 0.000
S72.3 Fracture of shaft of femur
0.638 0.362 0.000
M86 Osteomyelitis
0.638 0.362 0.000
C77.1 Intrathoracic lymph nodes
0.638 0.362 0.000
M19.1 Posttraumatic arthrosis of other joints
0.638 0.362 0.000
S68 Traumatic amputation of wrist and hand
0.637 0.363 0.000
M80-M85 Disorders of bone density and structure
0.637 0.363 0.000
S62.61 Fracture of other finger (open)
0.636 0.364 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.636 0.364 0.000
M47.2 Other spondylosis with radiculopathy
0.636 0.364 0.000
M21.0 Valgus deformity, not elsewhere classified
0.636 0.364 0.000
K09 Cysts of oral region, not elsewhere classified
0.635 0.364 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.635 0.365 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.635 0.365 0.000
M20.0 Deformity of finger(s)
0.634 0.366 0.000
J38.3 Other diseases of vocal cords
0.633 0.367 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.633 0.367 0.000
K30 Dyspepsia
0.631 0.369 0.000
N60.2 Fibroadenosis of breast
0.631 0.369 0.000
S12 Fracture of neck
0.631 0.369 0.000
D80-D89 Certain disorders involving the immune mechanism
0.631 0.369 0.000
F33 Recurrent depressive disorder
0.631 0.369 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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