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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117492744
log Bayes Factor = 13.2788
Chromosome 12   position 29,747,631  (GRCh37) Explore rs117492744 on Ensembl!
Variant rs117492744 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Z51.1 Chemotherapy session for neoplasm
0.998 0.002 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.997 0.003 0.000
Z51 Other medical care
0.996 0.004 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.996 0.004 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.994 0.006 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.987 0.013 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.987 0.013 0.000
R50-R69 General symptoms and signs
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.975 0.025 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.973 0.027 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.968 0.032 0.000
C51-C58 Malignant neoplasms of female genital organs
0.964 0.036 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.958 0.042 0.000
O00-O08 Pregnancy with abortive outcome
0.957 0.043 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.952 0.048 0.000
C56 Malignant neoplasm of ovary
0.946 0.054 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.944 0.056 0.000
Z37 Outcome of delivery
0.942 0.058 0.000
O80-O84 Delivery
0.941 0.059 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.940 0.060 0.000
O03 Spontaneous abortion
0.937 0.063 0.000
O03.9 Complete or unspecified, without complication
0.926 0.074 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.920 0.080 0.000
Z37.0 Single live birth
0.920 0.080 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.914 0.086 0.000
R63 Symptoms and signs concerning food and fluid intake
0.913 0.087 0.000
E70-E90 Metabolic disorders
0.911 0.089 0.000
C83.3 Large cell (diffuse)
0.910 0.090 0.000
E50-E64 Other nutritional deficiencies
0.909 0.091 0.000
O60-O75 Complications of labour and delivery
0.909 0.091 0.000
E65-E68 Obesity and other hyperalimentation
0.907 0.093 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.906 0.094 0.000
Chapter XIV Diseases of the genitourinary system
0.905 0.095 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.905 0.095 0.000
R53 Malaise and fatigue
0.901 0.099 0.000
C90.0 Multiple myeloma
0.901 0.099 0.000
D60-D64 Aplastic and other anaemias
0.893 0.107 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.893 0.107 0.000
Chapter VI Diseases of the nervous system
0.893 0.107 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.891 0.109 0.000
R50 Fever of unknown origin
0.890 0.110 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.887 0.113 0.000
C15-C26 Malignant neoplasms of digestive organs
0.886 0.114 0.000
D68 Other coagulation defects
0.885 0.115 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.882 0.118 0.000
R52 Pain, not elsewhere classified
0.881 0.119 0.000
D73 Diseases of spleen
0.881 0.119 0.000
Chapter XX External causes of morbidity and mortality
0.879 0.121 0.000
O80 Single spontaneous delivery
0.869 0.131 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.868 0.132 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.865 0.135 0.000
E66 Obesity
0.859 0.141 0.000
E53 Deficiency of other B group vitamins
0.851 0.149 0.000
R26 Abnormalities of gait and mobility
0.848 0.152 0.000
O36 Maternal care for other known or suspected foetal problems
0.846 0.154 0.000
Chapter XXII Codes for special purposes
0.845 0.155 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.845 0.155 0.000
Z33 Pregnant state, incidental
0.843 0.157 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.839 0.161 0.000
R25 Abnormal involuntary movements
0.839 0.161 0.000
Z36 Antenatal screening
0.837 0.163 0.000
R51 Headache
0.834 0.166 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.831 0.169 0.000
R94 Abnormal results of function studies
0.831 0.169 0.000
Z50 Care involving use of rehabilitation procedures
0.828 0.172 0.000
O80.0 Spontaneous vertex delivery
0.828 0.172 0.000
E86 Volume depletion
0.827 0.173 0.000
D73.0 Hyposplenism
0.826 0.174 0.000
E66.9 Obesity, unspecified
0.823 0.177 0.000
O47 False labour
0.818 0.182 0.000
Z35 Supervision of high-risk pregnancy
0.817 0.183 0.000
Z41 Procedures for purposes other than remedying health state
0.816 0.184 0.000
Z34 Supervision of normal pregnancy
0.816 0.184 0.000
E83 Disorders of mineral metabolism
0.814 0.186 0.000
R60 Oedema, not elsewhere classified
0.813 0.187 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.813 0.187 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.812 0.188 0.000
R63.4 Abnormal weight loss
0.812 0.188 0.000
E53.8 Deficiency of other specified B group vitamins
0.810 0.190 0.000
R29.6 Tendency to fall, not elsewhere classified
0.809 0.191 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.809 0.191 0.000
R63.8 Other symptoms and signs concerning food and fluid intake
0.801 0.199 0.000
N17-N19 Renal failure
0.799 0.201 0.000
G20-G26 Extrapyramidal and movement disorders
0.798 0.202 0.000
O42 Premature rupture of membranes
0.794 0.206 0.000
C92 Myeloid leukaemia
0.792 0.208 0.000
C64-C68 Malignant neoplasms of urinary tract
0.792 0.208 0.000
Z52 Donors of organs and tissues
0.787 0.213 0.000
O20 Haemorrhage in early pregnancy
0.787 0.213 0.000
R94.5 Abnormal results of liver function studies
0.787 0.213 0.000
R61 Hyperhidrosis
0.786 0.214 0.000
Z50.1 Other physical therapy
0.786 0.214 0.000
R30-R39 Symptoms and signs involving the urinary system
0.786 0.214 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.785 0.215 0.000
R57 Shock, not elsewhere classified
0.784 0.216 0.000
O82 Single delivery by Caesarean section
0.783 0.217 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.783 0.217 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.782 0.218 0.000
O85-O92 Complications predominantly related to the puerperium
0.780 0.220 0.000
D75 Other diseases of blood and blood-forming organs
0.778 0.222 0.000
G90-G99 Other disorders of the nervous system
0.777 0.223 0.000
N00-N08 Glomerular diseases
0.777 0.223 0.000
D69 Purpura and other haemorrhagic conditions
0.776 0.224 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.776 0.224 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.776 0.224 0.000
Chapter I Certain infectious and parasitic diseases
0.775 0.225 0.000
Z49 Care involving dialysis
0.775 0.225 0.000
Z51.5 Palliative care
0.773 0.227 0.000
N18 Chronic renal failure
0.773 0.227 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.772 0.228 0.000
R31 Unspecified haematuria
0.772 0.228 0.000
N10-N16 Renal tubulo-interstitial diseases
0.772 0.228 0.000
Chapter VIII Diseases of the ear and mastoid process
0.770 0.229 0.000
C50-C50 Malignant neoplasm of breast
0.765 0.235 0.000
Z43 Attention to artificial openings
0.765 0.235 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.764 0.236 0.000
R58 Haemorrhage, not elsewhere classified
0.764 0.236 0.000
Z31 Procreative management
0.764 0.236 0.000
D50-D53 Nutritional anaemias
0.763 0.237 0.000
O72 Postpartum haemorrhage
0.763 0.237 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.763 0.237 0.000
O41 Other disorders of amniotic fluid and membranes
0.762 0.238 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.762 0.238 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.762 0.238 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.761 0.239 0.000
C18 Malignant neoplasm of colon
0.761 0.239 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.761 0.239 0.000
D70 Agranulocytosis
0.761 0.239 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.759 0.241 0.000
N60-N64 Disorders of breast
0.757 0.243 0.000
R80 Isolated proteinuria
0.755 0.245 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.755 0.245 0.000
R50.0 Fever with chills
0.754 0.246 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.754 0.246 0.000
D72 Other disorders of white blood cells
0.753 0.247 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.752 0.248 0.000
R47-R49 Symptoms and signs involving speech and voice
0.748 0.251 0.000
R87 Abnormal findings in specimens from female genital organs
0.746 0.254 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.745 0.255 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.745 0.255 0.000
R81 Glycosuria
0.743 0.257 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.742 0.257 0.000
D62 Acute posthaemorrhagic anaemia
0.740 0.260 0.000
R52.1 Chronic intractable pain
0.739 0.261 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.739 0.261 0.000
Z32 Pregnancy examination and test
0.739 0.261 0.000
D61 Other aplastic anaemias
0.735 0.265 0.000
R27 Other lack of coordination
0.735 0.265 0.000
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm
0.735 0.265 0.000
N18.3 Chronic kidney disease, stage 3
0.734 0.266 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.734 0.266 0.000
R52.2 Other chronic pain
0.734 0.266 0.000
Chapter X Diseases of the respiratory system
0.733 0.267 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.733 0.267 0.000
O44 Placenta praevia
0.731 0.269 0.000
Z51.3 Blood transfusion without reported diagnosis
0.730 0.270 0.000
Z13 Special screening examination for other diseases and disorders
0.730 0.270 0.000
O48 Prolonged pregnancy
0.726 0.274 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.726 0.274 0.000
O20.0 Threatened abortion
0.725 0.275 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.724 0.276 0.000
Z63 Other problems related to primary support group, including family circumstances
0.724 0.276 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.724 0.276 0.000
G62 Other polyneuropathies
0.723 0.277 0.000
R50.9 Fever, unspecified
0.721 0.279 0.000
Chapter XI Diseases of the digestive system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
D45 Polycythaemia vera
0.716 0.284 0.000
D55-D59 Haemolytic anaemias
0.714 0.285 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.714 0.286 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.714 0.286 0.000
Z51.9 Medical care, unspecified
0.714 0.286 0.000
Z51.6 Desensitisation to allergens
0.714 0.286 0.000
Z51.0 Radiotherapy session
0.714 0.286 0.000
Z54 Convalescence
0.714 0.286 0.000
Z44 Fitting and adjustment of external prosthetic device
0.714 0.286 0.000
D68.2 Hereditary deficiency of other clotting factors
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.713 0.287 0.000
C95 Leukaemia of unspecified cell type
0.713 0.287 0.000
C94 Other leukaemias of specified cell type
0.713 0.287 0.000
C93 Monocytic leukaemia
0.713 0.287 0.000
C88 Malignant immunoproliferative diseases
0.713 0.287 0.000
C86 Other specified types of T/NK-cell lymphoma
0.713 0.287 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.713 0.287 0.000
C81 Hodgkin's disease
0.713 0.287 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.713 0.287 0.000
N63 Unspecified lump in breast
0.711 0.289 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.710 0.290 0.000
C45 Mesothelioma
0.709 0.291 0.000
Z38 Liveborn infants according to place of birth
0.708 0.292 0.000
R68 Other general symptoms and signs
0.707 0.292 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.707 0.292 0.000
R62 Lack of expected normal physiological development
0.707 0.292 0.000
R64 Cachexia
0.707 0.292 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.707 0.293 0.000
D68.5 Primary Thrombophilia
0.706 0.294 0.000
C25 Malignant neoplasm of pancreas
0.705 0.295 0.000
D68.0 Von Willebrand's disease
0.705 0.295 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.704 0.296 0.000
K42 Umbilical hernia
0.704 0.296 0.000
D68.9 Coagulation defect, unspecified
0.702 0.298 0.000
O70 Perineal laceration during delivery
0.702 0.298 0.000
G20 Parkinson's disease
0.701 0.299 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.700 0.300 0.000
R50.8 Other specified fever
0.700 0.300 0.000
O46.9 Antepartum haemorrhage, unspecified
0.698 0.302 0.000
K40-K46 Hernia
0.698 0.302 0.000
E83.5 Disorders of calcium metabolism
0.698 0.302 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.698 0.302 0.000
O45 Premature separation of placenta [abruptio placentae]
0.697 0.303 0.000
O43 Placental disorders
0.697 0.303 0.000
O33 Maternal care for known or suspected disproportion
0.697 0.303 0.000
O31 Complications specific to multiple gestation
0.697 0.303 0.000
O40 Polyhydramnios
0.697 0.303 0.000
E20-E35 Disorders of other endocrine glands
0.697 0.303 0.000
O16 Unspecified maternal hypertension
0.695 0.305 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.694 0.306 0.000
C83.7 Burkitt's tumour
0.694 0.306 0.000
C83.6 Undifferentiated (diffuse)
0.694 0.306 0.000
C83.5 Lymphoblastic (diffuse)
0.694 0.306 0.000
C83.4 Immunoblastic (diffuse)
0.694 0.306 0.000
C83.2 Mixed small and large cell (diffuse)
0.694 0.306 0.000
C83.1 Small cleaved cell (diffuse)
0.694 0.306 0.000
C83.0 Small cell (diffuse)
0.694 0.306 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.691 0.309 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.691 0.309 0.000
C53 Malignant neoplasm of cervix uteri
0.691 0.309 0.000
C51 Malignant neoplasm of vulva
0.691 0.309 0.000
C58 Malignant neoplasm of placenta
0.691 0.309 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.691 0.309 0.000
C52 Malignant neoplasm of vagina
0.691 0.309 0.000
D68.3 Haemorrhagic disorder due to circulating anticoagulants
0.691 0.309 0.000
W20-W49 Exposure to inanimate mechanical forces
0.690 0.310 0.000
R60.0 Localised oedema
0.688 0.312 0.000
R25.1 Tremor, unspecified
0.688 0.312 0.000
Z41.1 Other plastic surgery for unacceptable cosmetic appearance
0.687 0.313 0.000
E40-E46 Malnutrition
0.687 0.313 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.686 0.313 0.000
D74 Methaemoglobinaemia
0.686 0.313 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.686 0.313 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.686 0.313 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.686 0.313 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.686 0.314 0.000
O07 Failed attempted abortion
0.686 0.314 0.000
O06 Unspecified abortion
0.686 0.314 0.000
O05 Other abortion
0.686 0.314 0.000
O01 Hydatidiform mole
0.686 0.314 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.685 0.315 0.000
C15 Malignant neoplasm of oesophagus
0.685 0.315 0.000
O04 Medical abortion
0.685 0.315 0.000
A30-A49 Other bacterial diseases
0.685 0.315 0.000
O36.8 Maternal care for other specified foetal problems
0.684 0.316 0.000
Z72 Problems related to lifestyle
0.683 0.317 0.000
R29.4 Clicking hip
0.683 0.317 0.000
R29.3 Abnormal posture
0.683 0.317 0.000
R29.2 Abnormal reflex
0.683 0.317 0.000
R29.1 Meningismus
0.683 0.317 0.000
R29.0 Tetany
0.683 0.317 0.000
N13 Obstructive and reflux uropathy
0.681 0.319 0.000
J40-J47 Chronic lower respiratory diseases
0.681 0.319 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.680 0.320 0.000
D80-D89 Certain disorders involving the immune mechanism
0.679 0.321 0.000
G30-G32 Other degenerative diseases of the nervous system
0.679 0.321 0.000
K86 Other diseases of pancreas
0.678 0.322 0.000
E61 Deficiency of other nutrient elements
0.678 0.322 0.000
D00-D09 In situ neoplasms
0.678 0.322 0.000
D67 Hereditary factor IX deficiency
0.677 0.323 0.000
D66 Hereditary factor VIII deficiency
0.677 0.323 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.677 0.323 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.676 0.323 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.676 0.324 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.676 0.324 0.000
E55 Vitamin D deficiency
0.676 0.324 0.000
Z37.9 Outcome of delivery unspecified
0.675 0.324 0.000
Z37.7 Other multiple births, all stillborn
0.675 0.324 0.000
Z37.6 Other multiple births, some liveborn
0.675 0.324 0.000
Z37.5 Other multiple births, all liveborn
0.675 0.324 0.000
Z37.4 Twins, both stillborn
0.675 0.324 0.000
Z37.3 Twins, one liveborn and one stillborn
0.675 0.324 0.000
Z37.1 Single stillbirth
0.675 0.324 0.000
Z35.5 Supervision of elderly primigravida
0.675 0.325 0.000
O84 Multiple delivery
0.675 0.325 0.000
O83 Other assisted single delivery
0.675 0.325 0.000
O81 Single delivery by forceps and vacuum extractor
0.675 0.325 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.675 0.325 0.000
X60-X84 Intentional self-harm
0.674 0.326 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.674 0.326 0.000
C90.3 Solitary plasmacytoma
0.674 0.326 0.000
C90.2 Plasmacytoma, extramedullary
0.674 0.326 0.000
C90.1 Plasma cell leukaemia
0.674 0.326 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.673 0.327 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.672 0.328 0.000
O03.8 Complete or unspecified, with other and unspecified complications
0.672 0.328 0.000
O03.7 Complete or unspecified, complicated by embolism
0.672 0.328 0.000
O03.6 Complete or unspecified, complicated by delayed or excessive haemorrhage
0.672 0.328 0.000
O03.5 Complete or unspecified, complicated by genital tract and pelvic infection
0.672 0.328 0.000
O03.3 Incomplete, with other and unspecified complications
0.672 0.328 0.000
O03.2 Incomplete, complicated by embolism
0.672 0.328 0.000
O03.1 Incomplete, complicated by delayed or excessive haemorrhage
0.672 0.328 0.000
O03.0 Incomplete, complicated by genital tract and pelvic infection
0.672 0.328 0.000
Z12 Special screening examination for neoplasms
0.671 0.329 0.000
G62.9 Polyneuropathy, unspecified
0.671 0.329 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.669 0.331 0.000
Z11.0 Special screening examination for intestinal infectious diseases
0.669 0.331 0.000
D68.8 Other specified coagulation defects
0.669 0.331 0.000
C18.6 Descending colon
0.669 0.331 0.000
O00 Ectopic pregnancy
0.668 0.332 0.000
Z50.0 Cardiac rehabilitation
0.668 0.332 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.668 0.332 0.000
R59 Enlarged lymph nodes
0.666 0.334 0.000
D48.6 Breast
0.666 0.334 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.666 0.334 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.664 0.335 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.664 0.336 0.000
Z13.1 Special screening examination for diabetes mellitus
0.664 0.336 0.000
O62 Abnormalities of forces of labour
0.662 0.338 0.000
E83.4 Disorders of magnesium metabolism
0.661 0.339 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.661 0.339 0.000
C91 Lymphoid leukaemia
0.661 0.339 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.660 0.340 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.660 0.340 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.660 0.340 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.660 0.340 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.660 0.340 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.660 0.340 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.660 0.340 0.000
R87.6 Abnormal cytological findings
0.660 0.340 0.000
R82 Other abnormal findings in urine
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.342 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.658 0.342 0.000
R52.9 Pain, unspecified
0.656 0.344 0.000
N81 Female genital prolapse
0.656 0.344 0.000
O23 Infections of genito-urinary tract in pregnancy
0.655 0.345 0.000
Z10 Routine general health check-up of defined subpopulation
0.655 0.345 0.000
Z34.0 Supervision of normal first pregnancy
0.655 0.345 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.655 0.345 0.000
R63.5 Abnormal weight gain
0.655 0.345 0.000
R63.3 Feeding difficulties and mismanagement
0.655 0.345 0.000
R63.2 Polyphagia
0.655 0.345 0.000
R63.1 Polydipsia
0.655 0.345 0.000
O30 Multiple gestation
0.654 0.346 0.000
N76 Other inflammation of vagina and vulva
0.654 0.346 0.000
G93 Other disorders of brain
0.654 0.346 0.000
E85 Amyloidosis
0.653 0.347 0.000
E84 Cystic fibrosis
0.653 0.347 0.000
E79 Disorders of purine and pyrimidine metabolism
0.653 0.347 0.000
E77 Disorders of glycoprotein metabolism
0.653 0.347 0.000
E76 Disorders of glycosaminoglycan metabolism
0.653 0.347 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.653 0.347 0.000
E74 Other disorders of carbohydrate metabolism
0.653 0.347 0.000
E73 Lactose intolerance
0.653 0.347 0.000
E72 Other disorders of amino-acid metabolism
0.653 0.347 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.653 0.347 0.000
E70 Disorders of aromatic amino-acid metabolism
0.653 0.347 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.653 0.347 0.000
O21 Excessive vomiting in pregnancy
0.653 0.347 0.000
O36.6 Maternal care for excessive foetal growth
0.653 0.347 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.652 0.348 0.000
E63 Other nutritional deficiencies
0.652 0.348 0.000
E56 Other vitamin deficiencies
0.652 0.348 0.000
E51 Thiamine deficiency
0.652 0.348 0.000
E50 Vitamin A deficiency
0.652 0.348 0.000
E60 Dietary zinc deficiency
0.652 0.348 0.000
E59 Dietary selenium deficiency
0.652 0.348 0.000
E58 Dietary calcium deficiency
0.652 0.348 0.000
E54 Ascorbic acid deficiency
0.652 0.348 0.000
E52 Niacin deficiency [pellagra]
0.652 0.348 0.000
O74 Complications of anaesthesia during labour and delivery
0.652 0.348 0.000
O73 Retained placenta and membranes, without haemorrhage
0.652 0.348 0.000
O71 Other obstetric trauma
0.652 0.348 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.652 0.348 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.652 0.348 0.000
O61 Failed induction of labour
0.652 0.348 0.000
O60 Preterm delivery
0.652 0.348 0.000
G70-G73 Diseases of myoneural junction and muscle
0.652 0.348 0.000
W00-W19 Falls
0.651 0.349 0.000
E67 Other hyperalimentation
0.651 0.349 0.000
E68 Sequelae of hyperalimentation
0.651 0.349 0.000
E65 Localised adiposity
0.651 0.349 0.000
N02 Recurrent and persistent haematuria
0.650 0.349 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.650 0.350 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.649 0.350 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.649 0.351 0.000
O36.5 Maternal care for poor foetal growth
0.648 0.352 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.647 0.353 0.000
H80-H83 Diseases of inner ear
0.647 0.353 0.000
O24 Diabetes mellitus in pregnancy
0.646 0.353 0.000
S20-S29 Injuries to the thorax
0.646 0.354 0.000
Z34.8 Supervision of other normal pregnancy
0.645 0.355 0.000
Z29 Need for other prophylactic measures
0.644 0.356 0.000
C92.1 Chronic myeloid leukaemia
0.643 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.643 0.357 0.000
G25 Other extrapyramidal and movement disorders
0.642 0.357 0.000
R61.9 Hyperhidrosis, unspecified
0.642 0.358 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.641 0.359 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.641 0.359 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.640 0.360 0.000
N73 Other female pelvic inflammatory diseases
0.640 0.360 0.000
C78.7 Secondary malignant neoplasm of liver
0.639 0.361 0.000
R57.2 Septic shock
0.639 0.361 0.000
O29 Complications of anaesthesia during pregnancy
0.639 0.361 0.000
O28 Abnormal findings on antenatal screening of mother
0.639 0.361 0.000
O22 Venous complications in pregnancy
0.639 0.361 0.000
O25 Malnutrition in pregnancy
0.639 0.361 0.000
E83.3 Disorders of phosphorus metabolism
0.639 0.361 0.000
R50.2 Drug-induced fever
0.638 0.362 0.000
R50.1 Persistent fever
0.638 0.362 0.000
D69.6 Thrombocytopenia, unspecified
0.638 0.362 0.000
Z52.4 Kidney donor
0.638 0.362 0.000
R26.3 Immobility
0.638 0.362 0.000
O82.0 Delivery by elective Caesarean section
0.637 0.362 0.000
V80-V89 Other land transport accidents
0.637 0.363 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.636 0.364 0.000
D46 Myelodysplastic syndromes
0.635 0.364 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.635 0.365 0.000
C21 Malignant neoplasm of anus and anal canal
0.635 0.365 0.000
C17 Malignant neoplasm of small intestine
0.635 0.365 0.000
C23 Malignant neoplasm of gallbladder
0.635 0.365 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.635 0.365 0.000
Z74 Problems related to care-provider dependency
0.635 0.365 0.000
O69.1 Labour and delivery complicated by cord around neck, with compression
0.634 0.365 0.000
D68.6 Other Thrombophilia
0.634 0.366 0.000
D68.4 Acquired coagulation factor deficiency
0.634 0.366 0.000
D68.1 Hereditary factor XI deficiency
0.634 0.366 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.634 0.366 0.000
Z08.8 Follow-up examination after other treatment for malignant neoplasm
0.633 0.367 0.000
Z43.2 Attention to ileostomy
0.633 0.367 0.000
Z48 Other surgical follow-up care
0.632 0.368 0.000
R52.0 Acute pain
0.632 0.368 0.000
O66 Other obstructed labour
0.631 0.368 0.000
D73.9 Disease of spleen, unspecified
0.631 0.368 0.000
D73.8 Other diseases of spleen
0.631 0.368 0.000
D73.5 Infarction of spleen
0.631 0.368 0.000
D73.4 Cyst of spleen
0.631 0.368 0.000
D73.3 Abscess of spleen
0.631 0.368 0.000
D73.2 Chronic congestive splenomegaly
0.631 0.368 0.000
D73.1 Hypersplenism
0.631 0.368 0.000
C60-C63 Malignant neoplasms of male genital organs
0.631 0.369 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.631 0.369 0.000
Y35-Y36 Legal intervention and operations of war
0.630 0.369 0.000
Y10-Y34 Event of undetermined intent
0.630 0.369 0.000
Y00-Y09 Assault
0.630 0.369 0.000
X85-X99 Assault
0.630 0.369 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.630 0.369 0.000
X50-X57 Overexertion, travel and privation
0.630 0.369 0.000
X30-X39 Exposure to forces of nature
0.630 0.369 0.000
X20-X29 Contact with venomous animals and plants
0.630 0.369 0.000
X10-X19 Contact with heat and hot substances
0.630 0.369 0.000
X00-X09 Exposure to smoke, fire and flames
0.630 0.369 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.630 0.369 0.000
W75-W84 Other accidental threats to breathing
0.630 0.369 0.000
W65-W74 Accidental drowning and submersion
0.630 0.369 0.000
W50-W64 Exposure to animate mechanical forces
0.630 0.369 0.000
V98-V99 Other and unspecified transport accidents
0.630 0.369 0.000
V95-V97 Air and space transport accidents
0.630 0.369 0.000
V90-V94 Water transport accidents
0.630 0.369 0.000
V70-V79 Bus occupant injured in transport accident
0.630 0.369 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.630 0.369 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.630 0.369 0.000
V40-V49 Car occupant injured in transport accident
0.630 0.369 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.630 0.369 0.000
V20-V29 Motorcycle rider injured in transport accident
0.630 0.369 0.000
V01-V09 Pedestrian injured in transport accident
0.630 0.369 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.630 0.370 0.000
O36.9 Maternal care for foetal problem, unspecified
0.627 0.373 0.000
Z39 Postpartum care and examination
0.626 0.374 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.625 0.375 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.625 0.375 0.000
D48.7 Other specified sites
0.624 0.376 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.624 0.376 0.000
B50-B64 Protozoal diseases
0.624 0.376 0.000
N11 Chronic tubulo-interstitial nephritis
0.624 0.376 0.000
O80.8 Other single spontaneous delivery
0.623 0.377 0.000
O80.1 Spontaneous breech delivery
0.623 0.377 0.000
Z72.1 Alcohol use
0.623 0.377 0.000
O90 Complications of the puerperium, not elsewhere classified
0.622 0.378 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.622 0.378 0.000
R86 Abnormal findings in specimens from male genital organs
0.622 0.378 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.622 0.378 0.000
R83 Abnormal findings in cerebrospinal fluid
0.622 0.378 0.000
D61.9 Aplastic anaemia, unspecified
0.622 0.378 0.000
N81.1 Cystocele
0.622 0.378 0.000
D37.4 Colon
0.622 0.378 0.000
Z40 Prophylactic surgery
0.622 0.378 0.000
Z57 Occupational exposure to risk-factors
0.622 0.378 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.622 0.378 0.000
E66.8 Other obesity
0.621 0.379 0.000
Y57 Other and unspecified drugs and medicaments
0.621 0.379 0.000
K83 Other diseases of biliary tract
0.620 0.380 0.000
O15 Eclampsia
0.620 0.380 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.620 0.380 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.620 0.380 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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