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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs11751494
log Bayes Factor = 31.4605
Chromosome 6   position 33,804,669  (GRCh37) Explore rs11751494 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
E10.9 Without complications
1.000 0.000 0.000
E10 Insulin-dependent diabetes mellitus
1.000 0.000 0.000
E10-E14 Diabetes mellitus
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
M06.9 Rheumatoid arthritis, unspecified
1.000 0.000 0.000
M05-M14 Inflammatory polyarthropathies
1.000 0.000 0.000
M06 Other rheumatoid arthritis
1.000 0.000 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
1.000 0.000 0.000
D50-D53 Nutritional anaemias
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
1.000 0.000 0.000
D50 Iron deficiency anaemia
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.999 0.001 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.996 0.004 0.000
Chapter VII Diseases of the eye and adnexa
0.995 0.005 0.000
D50.8 Other iron deficiency anaemias
0.994 0.006 0.000
E16 Other disorders of pancreatic internal secretion
0.994 0.006 0.000
E11.9 Without complications
0.993 0.007 0.000
Chapter VIII Diseases of the ear and mastoid process
0.993 0.007 0.000
E16.2 Hypoglycaemia, unspecified
0.992 0.008 0.000
D50.9 Iron deficiency anaemia, unspecified
0.991 0.009 0.000
M05 Seropositive rheumatoid arthritis
0.988 0.012 0.000
M75 Shoulder lesions
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.983 0.017 0.000
E10.3 With ophthalmic complications
0.979 0.021 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.979 0.021 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.977 0.023 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.972 0.028 0.000
M50-M54 Other dorsopathies
0.972 0.028 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.971 0.029 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.971 0.029 0.000
M05.90 Seropositive rheumatoid arthritis, unspecified (Multiple sites)
0.970 0.030 0.000
H30-H36 Disorders of choroid and retina
0.960 0.040 0.000
E10.1 With ketoacidosis
0.959 0.041 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.952 0.048 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.950 0.050 0.000
H36 Retinal disorders in diseases classified elsewhere
0.948 0.052 0.000
E11.3 With ophthalmic complications
0.945 0.055 0.000
Chapter XX External causes of morbidity and mortality
0.944 0.056 0.000
Chapter VI Diseases of the nervous system
0.944 0.056 0.000
R12 Heartburn
0.940 0.060 0.000
H36.0 Diabetic retinopathy
0.940 0.060 0.000
M75.4 Impingement syndrome of shoulder
0.939 0.061 0.000
H65-H75 Diseases of middle ear and mastoid
0.938 0.062 0.000
H60-H62 Diseases of external ear
0.935 0.065 0.000
R79 Other abnormal findings of blood chemistry
0.932 0.068 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.926 0.074 0.000
M75.0 Adhesive capsulitis of shoulder
0.925 0.075 0.000
E14 Unspecified diabetes mellitus
0.925 0.075 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.921 0.079 0.000
M80-M85 Disorders of bone density and structure
0.918 0.082 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.918 0.082 0.000
M54 Dorsalgia
0.912 0.088 0.000
B35-B49 Mycoses
0.908 0.092 0.000
B25-B34 Other viral diseases
0.906 0.094 0.000
H04 Disorders of lachrymal system
0.906 0.094 0.000
Chapter XI Diseases of the digestive system
0.904 0.096 0.000
M51 Other intervertebral disk disorders
0.903 0.097 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.903 0.097 0.000
K70-K77 Diseases of liver
0.899 0.101 0.000
E10.4 With neurological complications
0.899 0.101 0.000
H80-H83 Diseases of inner ear
0.896 0.104 0.000
M79.0 Rheumatism, unspecified
0.895 0.105 0.000
R18 Ascites
0.889 0.111 0.000
R17 Unspecified jaundice
0.886 0.114 0.000
M65-M68 Disorders of synovium and tendon
0.885 0.115 0.000
E11.2 With renal complications
0.883 0.117 0.000
E11.4 With neurological complications
0.879 0.121 0.000
D51 Vitamin B12 deficiency anaemia
0.878 0.122 0.000
D60-D64 Aplastic and other anaemias
0.877 0.123 0.000
H02 Other disorders of eyelid
0.875 0.125 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.875 0.125 0.000
H60 Otitis externa
0.874 0.126 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.873 0.127 0.000
E00-E07 Disorders of thyroid gland
0.865 0.135 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.864 0.136 0.000
M51.2 Other specified intervertebral disk displacement
0.861 0.139 0.000
A30-A49 Other bacterial diseases
0.857 0.143 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.857 0.143 0.000
H04.2 Epiphora
0.851 0.149 0.000
E10.2 With renal complications
0.848 0.151 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.848 0.152 0.000
K80 Cholelithiasis
0.848 0.152 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.838 0.162 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.837 0.163 0.000
B34 Viral infection of unspecified site
0.837 0.163 0.000
M79.7 Fibromyalgia
0.835 0.165 0.000
M91-M94 Chondropathies
0.834 0.166 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.833 0.167 0.000
K75 Other inflammatory liver diseases
0.833 0.167 0.000
E40-E46 Malnutrition
0.832 0.168 0.000
M72 Fibroblastic disorders
0.831 0.169 0.000
H60.9 Otitis externa, unspecified
0.829 0.171 0.000
M54.5 Low back pain
0.828 0.172 0.000
G90-G99 Other disorders of the nervous system
0.828 0.172 0.000
H65 Nonsuppurative otitis media
0.824 0.176 0.000
R76 Other abnormal immunological findings in serum
0.824 0.176 0.000
E14.3 With ophthalmic complications
0.824 0.176 0.000
M75.5 Bursitis of shoulder
0.823 0.177 0.000
M84 Disorders of continuity of bone
0.822 0.178 0.000
M79.1 Myalgia
0.820 0.179 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.819 0.181 0.000
E20-E35 Disorders of other endocrine glands
0.819 0.181 0.000
H05 Disorders of orbit
0.818 0.182 0.000
H02.1 Ectropion of eyelid
0.815 0.185 0.000
G63.2 Diabetic polyneuropathy
0.814 0.186 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.813 0.187 0.000
M45-M49 Spondylopathies
0.811 0.188 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.810 0.190 0.000
E50-E64 Other nutritional deficiencies
0.809 0.191 0.000
K76 Other diseases of liver
0.808 0.192 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.807 0.193 0.000
B37 Candidiasis
0.805 0.195 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.804 0.196 0.000
H34 Retinal vascular occlusions
0.802 0.198 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.802 0.198 0.000
M75.2 Bicipital tendinitis
0.802 0.198 0.000
H55-H59 Other disorders of eye and adnexa
0.802 0.198 0.000
G30-G32 Other degenerative diseases of the nervous system
0.797 0.203 0.000
M40-M43 Deforming dorsopathies
0.795 0.205 0.000
M05.99 Seropositive rheumatoid arthritis, unspecified (Site unspecified)
0.794 0.206 0.000
M06.3 Rheumatoid nodule
0.794 0.206 0.000
G62 Other polyneuropathies
0.793 0.207 0.000
E70-E90 Metabolic disorders
0.792 0.208 0.000
E14.9 Without complications
0.788 0.212 0.000
B34.9 Viral infection, unspecified
0.787 0.213 0.000
H80 Otosclerosis
0.786 0.214 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.782 0.217 0.000
T66-T78 Other and unspecified effects of external causes
0.782 0.218 0.000
A49 Bacterial infection of unspecified site
0.779 0.221 0.000
E11.5 With peripheral circulatory complications
0.779 0.221 0.000
D69 Purpura and other haemorrhagic conditions
0.779 0.221 0.000
K70 Alcoholic liver disease
0.777 0.223 0.000
M79.9 Soft tissue disorder, unspecified
0.776 0.224 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.776 0.224 0.000
B35 Dermatophytosis
0.775 0.225 0.000
E10.5 With peripheral circulatory complications
0.773 0.227 0.000
M81 Osteoporosis without pathological fracture
0.772 0.228 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.772 0.228 0.000
M79.2 Neuralgia and neuritis, unspecified
0.765 0.235 0.000
M54.2 Cervicalgia
0.765 0.235 0.000
K74 Fibrosis and cirrhosis of liver
0.762 0.238 0.000
H71 Cholesteatoma of middle ear
0.762 0.238 0.000
A80-A89 Viral infections of the central nervous system
0.761 0.239 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.758 0.242 0.000
Chapter XXII Codes for special purposes
0.758 0.242 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.757 0.243 0.000
K35-K38 Diseases of appendix
0.756 0.244 0.000
K86 Other diseases of pancreas
0.754 0.246 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.754 0.246 0.000
M71 Other bursopathies
0.753 0.247 0.000
H83 Other diseases of inner ear
0.752 0.248 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.751 0.249 0.000
H61 Other disorders of external ear
0.751 0.249 0.000
G61 Inflammatory polyneuropathy
0.749 0.251 0.000
M77 Other enthesopathies
0.749 0.251 0.000
K75.4 Autoimmune hepatitis
0.748 0.252 0.000
E04 Other non-toxic goitre
0.746 0.254 0.000
M65 Synovitis and tenosynovitis
0.746 0.254 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.745 0.255 0.000
H72 Perforation of tympanic membrane
0.745 0.255 0.000
K76.6 Portal hypertension
0.745 0.255 0.000
D51.9 Vitamin B12 deficiency anaemia, unspecified
0.743 0.257 0.000
Q60-Q64 Congenital malformations of the urinary system
0.743 0.257 0.000
H10-H13 Disorders of conjunctiva
0.743 0.257 0.000
W50-W64 Exposure to animate mechanical forces
0.742 0.258 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.742 0.258 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.741 0.259 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.741 0.259 0.000
M06.0 Seronegative rheumatoid arthritis
0.739 0.261 0.000
D80-D89 Certain disorders involving the immune mechanism
0.738 0.261 0.000
M79.79 Fibromyalgia (Site unspecified)
0.738 0.262 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.737 0.263 0.000
V10-V19 Pedal cyclist injured in transport accident
0.735 0.265 0.000
S80-S89 Injuries to the knee and lower leg
0.734 0.266 0.000
W00-W19 Falls
0.734 0.266 0.000
A63 Other predominantly sexually transmitted diseases, not elsewhere classified
0.734 0.266 0.000
R76.8 Other specified abnormal immunological findings in serum
0.732 0.268 0.000
H65.9 Nonsuppurative otitis media, unspecified
0.731 0.269 0.000
M11 Other crystal arthropathies
0.730 0.270 0.000
R87 Abnormal findings in specimens from female genital organs
0.730 0.270 0.000
B37.8 Candidiasis of other sites
0.730 0.270 0.000
M79.5 Residual foreign body in soft tissue
0.730 0.270 0.000
H66 Suppurative and unspecified otitis media
0.730 0.270 0.000
M75.9 Shoulder lesion, unspecified
0.730 0.270 0.000
M10 Gout
0.729 0.271 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.727 0.273 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.726 0.274 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.724 0.276 0.000
T78 Adverse effects, not elsewhere classified
0.724 0.276 0.000
H00 Hordeolum and chalazion
0.723 0.277 0.000
M00-M03 Infectious arthropathies
0.720 0.280 0.000
K72 Hepatic failure, not elsewhere classified
0.720 0.280 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.719 0.281 0.000
H53-H54 Visual disturbances and blindness
0.719 0.281 0.000
D51.0 Vitamin B12 deficiency anaemia due to intrinsic factor deficiency
0.719 0.281 0.000
E10.8 With unspecified complications
0.717 0.283 0.000
E10.7 With multiple complications
0.717 0.283 0.000
E10.6 With other specified complications
0.717 0.283 0.000
E10.0 With coma
0.717 0.283 0.000
E13 Other specified diabetes mellitus
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M14 Arthropathies in other diseases classified elsewhere
0.717 0.283 0.000
M12 Other specific arthropathies
0.717 0.283 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.717 0.283 0.000
M08 Juvenile arthritis
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.717 0.283 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.717 0.283 0.000
M06.8 Other specified rheumatoid arthritis
0.717 0.283 0.000
M06.4 Inflammatory polyarthropathy
0.717 0.283 0.000
M06.2 Rheumatoid bursitis
0.717 0.283 0.000
M06.1 Adult-onset Still's disease
0.717 0.283 0.000
M86-M90 Other osteopathies
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.6 With other specified complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E11.0 With coma
0.717 0.283 0.000
D53 Other nutritional anaemias
0.717 0.283 0.000
D50.1 Sideropenic dysphagia
0.717 0.283 0.000
R14 Flatulence and related conditions
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.284 0.000
M94 Other disorders of cartilage
0.715 0.285 0.000
E15 Nondiabetic hypoglycaemic coma
0.714 0.286 0.000
S70-S79 Injuries to the hip and thigh
0.714 0.286 0.000
M54.56 Low back pain (Lumbar region)
0.714 0.286 0.000
E16.9 Disorder of pancreatic internal secretion, unspecified
0.713 0.287 0.000
E16.8 Other specified disorders of pancreatic internal secretion
0.713 0.287 0.000
E16.4 Abnormal secretion of gastrin
0.713 0.287 0.000
E16.3 Increased secretion of glucagon
0.713 0.287 0.000
E16.1 Other hypoglycaemia
0.713 0.287 0.000
E16.0 Drug-induced hypoglycaemia without coma
0.713 0.287 0.000
G20-G26 Extrapyramidal and movement disorders
0.713 0.287 0.000
E46 Unspecified protein-energy malnutrition
0.711 0.289 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.711 0.289 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.710 0.290 0.000
E86 Volume depletion
0.709 0.291 0.000
D61 Other aplastic anaemias
0.708 0.291 0.000
A49.9 Bacterial infection, unspecified
0.708 0.292 0.000
M05.8 Other seropositive rheumatoid arthritis
0.708 0.292 0.000
M05.3 Rheumatoid arthritis with involvement of other organs and systems
0.708 0.292 0.000
M05.2 Rheumatoid vasculitis
0.708 0.292 0.000
M05.1 Rheumatoid lung disease
0.708 0.292 0.000
M05.0 Felty's syndrome
0.708 0.292 0.000
H80.9 Otosclerosis, unspecified
0.707 0.293 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.707 0.293 0.000
G62.9 Polyneuropathy, unspecified
0.707 0.293 0.000
M54.9 Dorsalgia, unspecified
0.707 0.293 0.000
M75.8 Other shoulder lesions
0.706 0.293 0.000
T79-T79 Certain early complications of trauma
0.706 0.294 0.000
X60-X84 Intentional self-harm
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.705 0.295 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.705 0.295 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.705 0.295 0.000
B65-B83 Helminthiases
0.705 0.295 0.000
B50-B64 Protozoal diseases
0.705 0.295 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.705 0.295 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.705 0.295 0.000
A75-A79 Rickettsioses
0.705 0.295 0.000
A70-A74 Other diseases caused by chlamydiae
0.705 0.295 0.000
A65-A69 Other spirochaetal diseases
0.705 0.295 0.000
A20-A28 Certain zoonotic bacterial diseases
0.705 0.295 0.000
A15-A19 Tuberculosis
0.705 0.295 0.000
B25 Cytomegaloviral disease
0.704 0.296 0.000
H05.8 Other disorders of orbit
0.704 0.296 0.000
M05.98 Seropositive rheumatoid arthritis, unspecified (Other)
0.702 0.298 0.000
M05.97 Seropositive rheumatoid arthritis, unspecified (Ankle and foot)
0.702 0.298 0.000
M05.96 Seropositive rheumatoid arthritis, unspecified (Lower leg)
0.702 0.298 0.000
M05.95 Seropositive rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.702 0.298 0.000
M05.94 Seropositive rheumatoid arthritis, unspecified (Hand)
0.702 0.298 0.000
M05.93 Seropositive rheumatoid arthritis, unspecified (Forearm)
0.702 0.298 0.000
M05.92 Seropositive rheumatoid arthritis, unspecified (Upper arm)
0.702 0.298 0.000
M05.91 Seropositive rheumatoid arthritis, unspecified (Shoulder region)
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.702 0.298 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.702 0.298 0.000
K75.8 Other specified inflammatory liver diseases
0.702 0.298 0.000
K85 Acute pancreatitis
0.702 0.298 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.700 0.299 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.700 0.300 0.000
G70-G73 Diseases of myoneural junction and muscle
0.700 0.300 0.000
M07 Psoriatic and enteropathic arthropathies
0.699 0.301 0.000
Y95 Nosocomial condition
0.698 0.302 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.697 0.303 0.000
W20-W49 Exposure to inanimate mechanical forces
0.697 0.303 0.000
M66 Spontaneous rupture of synovium and tendon
0.696 0.303 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.696 0.304 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.696 0.304 0.000
M79.3 Panniculitis, unspecified
0.696 0.304 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.696 0.304 0.000
S90-S99 Injuries to the ankle and foot
0.693 0.307 0.000
M79.10 Myalgia (Multiple sites)
0.692 0.308 0.000
H74 Other disorders of middle ear and mastoid
0.691 0.309 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.689 0.311 0.000
H31 Other disorders of choroid
0.689 0.311 0.000
H30 Chorioretinal inflammation
0.689 0.311 0.000
S40-S49 Injuries to the shoulder and upper arm
0.689 0.311 0.000
B35.1 Tinea unguium
0.688 0.312 0.000
T78.4 Allergy, unspecified
0.688 0.312 0.000
M47 Spondylosis
0.687 0.313 0.000
M85 Other disorders of bone density and structure
0.687 0.313 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.686 0.313 0.000
L91 Hypertrophic disorders of skin
0.686 0.314 0.000
M67 Other disorders of synovium and tendon
0.686 0.314 0.000
D64 Other anaemias
0.683 0.317 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.682 0.317 0.000
R77 Other abnormalities of plasma proteins
0.682 0.317 0.000
R74 Abnormal serum enzyme levels
0.682 0.317 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.682 0.317 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.682 0.317 0.000
R71 Abnormality of red blood cells
0.682 0.317 0.000
H36.8 Other retinal disorders in diseases classified elsewhere
0.680 0.320 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.679 0.321 0.000
G96 Other disorders of central nervous system
0.679 0.321 0.000
B15-B19 Viral hepatitis
0.677 0.323 0.000
Y35-Y36 Legal intervention and operations of war
0.677 0.323 0.000
Y10-Y34 Event of undetermined intent
0.677 0.323 0.000
Y00-Y09 Assault
0.677 0.323 0.000
X85-X99 Assault
0.677 0.323 0.000
X50-X57 Overexertion, travel and privation
0.677 0.323 0.000
X30-X39 Exposure to forces of nature
0.677 0.323 0.000
X20-X29 Contact with venomous animals and plants
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.677 0.323 0.000
X00-X09 Exposure to smoke, fire and flames
0.677 0.323 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.677 0.323 0.000
W75-W84 Other accidental threats to breathing
0.677 0.323 0.000
W65-W74 Accidental drowning and submersion
0.677 0.323 0.000
V98-V99 Other and unspecified transport accidents
0.677 0.323 0.000
V95-V97 Air and space transport accidents
0.677 0.323 0.000
V90-V94 Water transport accidents
0.677 0.323 0.000
V70-V79 Bus occupant injured in transport accident
0.677 0.323 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.677 0.323 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.677 0.323 0.000
V40-V49 Car occupant injured in transport accident
0.677 0.323 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.677 0.323 0.000
V01-V09 Pedestrian injured in transport accident
0.677 0.323 0.000
M53 Other dorsopathies, not elsewhere classified
0.675 0.325 0.000
E06 Thyroiditis
0.675 0.325 0.000
H17 Corneal scars and opacities
0.675 0.325 0.000
S20-S29 Injuries to the thorax
0.675 0.325 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.675 0.325 0.000
H73 Other disorders of tympanic membrane
0.675 0.325 0.000
D52 Folate deficiency anaemia
0.674 0.325 0.000
R79.0 Abnormal level of blood mineral
0.674 0.326 0.000
K74.6 Other and unspecified cirrhosis of liver
0.674 0.326 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.672 0.327 0.000
H70 Mastoiditis and related conditions
0.672 0.327 0.000
H69 Other disorders of Eustachian tube
0.672 0.327 0.000
H68 Eustachian salpingitis and obstruction
0.672 0.327 0.000
H67 Otitis media in diseases classified elsewhere
0.672 0.327 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.672 0.328 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.671 0.329 0.000
H62 Disorders of external ear in diseases classified elsewhere
0.670 0.330 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.669 0.331 0.000
S50-S59 Injuries to the elbow and forearm
0.667 0.333 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.667 0.333 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.665 0.335 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.665 0.335 0.000
E14.8 With unspecified complications
0.663 0.336 0.000
E14.7 With multiple complications
0.663 0.336 0.000
E14.6 With other specified complications
0.663 0.336 0.000
E14.5 With peripheral circulatory complications
0.663 0.336 0.000
E14.4 With neurological complications
0.663 0.336 0.000
E14.2 Withrenal complications
0.663 0.336 0.000
E14.1 With ketoacidosis
0.663 0.336 0.000
E14.0 With coma
0.663 0.336 0.000
K80.8 Other cholelithiasis
0.663 0.336 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.663 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.338 0.000
H02.8 Other specified disorders of eyelid
0.660 0.340 0.000
M65.3 Trigger finger
0.660 0.340 0.000
A63.0 Anogenital (venereal) warts
0.659 0.341 0.000
E53 Deficiency of other B group vitamins
0.658 0.341 0.000
M83 Adult osteomalacia
0.658 0.341 0.000
M82 Osteoporosis in diseases classified elsewhere
0.658 0.341 0.000
G60 Hereditary and idiopathic neuropathy
0.658 0.342 0.000
G64 Other disorders of peripheral nervous system
0.658 0.342 0.000
H02.3 Blepharochalasis
0.658 0.342 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.657 0.342 0.000
H25-H28 Disorders of lens
0.657 0.343 0.000
M54.57 Low back pain (Lumbosacral region)
0.657 0.343 0.000
H01 Other inflammation of eyelid
0.657 0.343 0.000
K86.8 Other specified diseases of pancreas
0.657 0.343 0.000
R47-R49 Symptoms and signs involving speech and voice
0.656 0.344 0.000
M54.8 Other dorsalgia
0.654 0.346 0.000
M54.6 Pain in thoracic spine
0.654 0.346 0.000
M54.0 Panniculitis affecting regions of neck and back
0.654 0.346 0.000
B48 Other mycoses, not elsewhere classified
0.651 0.349 0.000
B47 Mycetoma
0.651 0.349 0.000
B46 Zygomycosis
0.651 0.349 0.000
B45 Cryptococcosis
0.651 0.349 0.000
B44 Aspergillosis
0.651 0.349 0.000
B43 Chromomycosis and phaeomycotic abscess
0.651 0.349 0.000
B42 Sporotrichosis
0.651 0.349 0.000
B41 Paracoccidioidomycosis
0.651 0.349 0.000
B40 Blastomycosis
0.651 0.349 0.000
B39 Histoplasmosis
0.651 0.349 0.000
B38 Coccidioidomycosis
0.651 0.349 0.000
B36 Other superficial mycoses
0.651 0.349 0.000
B49 Unspecified mycosis
0.651 0.349 0.000
M54.4 Lumbago with sciatica
0.651 0.349 0.000
M54.1 Radiculopathy
0.651 0.349 0.000
H34.8 Other retinal vascular occlusions
0.651 0.349 0.000
M84.4 Pathological fracture, not elsewhere classified
0.650 0.350 0.000
B33 Other viral diseases, not elsewhere classified
0.650 0.350 0.000
B30 Viral conjunctivitis
0.650 0.350 0.000
B27 Infectious mononucleosis
0.650 0.350 0.000
B26 Mumps
0.650 0.350 0.000
B37.0 Candidal stomatitis
0.650 0.350 0.000
H04.9 Disorder of lachrymal system, unspecified
0.650 0.350 0.000
H04.8 Other disorders of lachrymal system
0.650 0.350 0.000
H04.6 Other changes in lachrymal passages
0.650 0.350 0.000
H04.4 Chronic inflammation of lachrymal passages
0.650 0.350 0.000
H04.3 Acute and unspecified inflammation of lachrymal passages
0.650 0.350 0.000
H04.0 Dacryoadenitis
0.650 0.350 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.649 0.350 0.000
H02.6 Xanthelasma of eyelid
0.649 0.350 0.000
L90 Atrophic disorders of skin
0.649 0.351 0.000
H83.0 Labyrinthitis
0.649 0.351 0.000
M51.3 Other specified intervertebral disk degeneration
0.647 0.352 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.647 0.352 0.000
M51.9 Intervertebral disk disorder, unspecified
0.647 0.352 0.000
M51.8 Other specified intervertebral disk disorders
0.647 0.352 0.000
M51.4 Schmorl's nodes
0.647 0.352 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.647 0.353 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.647 0.353 0.000
Q35-Q37 Cleft lip and cleft palate
0.647 0.353 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.647 0.353 0.000
L91.8 Other hypertrophic disorders of skin
0.647 0.353 0.000
M06.34 Rheumatoid nodule (Hand)
0.646 0.354 0.000
R87.6 Abnormal cytological findings
0.646 0.354 0.000
T90 Sequelae of injuries of head
0.646 0.354 0.000
Q50-Q56 Congenital malformations of genital organs
0.645 0.355 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.645 0.355 0.000
M79.8 Other specified soft tissue disorders
0.645 0.355 0.000
M84.0 Malunion of fracture
0.645 0.355 0.000
K77 Liver disorders in diseases classified elsewhere
0.644 0.356 0.000
K73 Chronic hepatitis, not elsewhere classified
0.644 0.356 0.000
K71 Toxic liver disease
0.644 0.356 0.000
H55 Nystagmus and other irregular eye movements
0.644 0.356 0.000
K70.1 Alcoholic hepatitis
0.644 0.356 0.000
D68 Other coagulation defects
0.644 0.356 0.000
E28 Ovarian dysfunction
0.644 0.356 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.643 0.357 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.643 0.357 0.000
M81.9 Osteoporosis, unspecified
0.643 0.357 0.000
G90 Disorders of autonomic nervous system
0.642 0.358 0.000
M79.08 Rheumatism, unspecified (Other)
0.642 0.358 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.642 0.358 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.642 0.358 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.642 0.358 0.000
M79.04 Rheumatism, unspecified (Hand)
0.642 0.358 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.642 0.358 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.642 0.358 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.642 0.358 0.000
H90-H95 Other disorders of ear
0.640 0.360 0.000
E88 Other metabolic disorders
0.638 0.361 0.000
H60.1 Cellulitis of external ear
0.638 0.362 0.000
K76.9 Liver disease, unspecified
0.637 0.363 0.000
M79.96 Soft tissue disorder, unspecified (Lower leg)
0.636 0.364 0.000
S82 Fracture of lower leg, including ankle
0.636 0.364 0.000
M43 Other deforming dorsopathies
0.636 0.364 0.000
E04.9 Non-toxic goitre, unspecified
0.635 0.365 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.634 0.366 0.000
G95 Other diseases of spinal cord
0.634 0.366 0.000
H34.2 Other retinal artery occlusions
0.633 0.367 0.000
D63.0 Anaemia in neoplastic disease
0.632 0.368 0.000
M50 Cervical disk disorders
0.631 0.369 0.000
H43-H45 Disorders of vitreous body and globe
0.631 0.369 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.631 0.369 0.000
V20-V29 Motorcycle rider injured in transport accident
0.630 0.370 0.000
D51.8 Other vitamin B12 deficiency anaemias
0.630 0.370 0.000
D51.3 Other dietary vitamin B12 deficiency anaemia
0.630 0.370 0.000
D51.2 Transcobalamin II deficiency
0.630 0.370 0.000
D51.1 Vitamin B12 deficiency anaemia due to selective vitamin B12 malabsorption with proteinuria
0.630 0.370 0.000
E27 Other disorders of adrenal gland
0.629 0.371 0.000
E61 Deficiency of other nutrient elements
0.629 0.371 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.629 0.371 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.628 0.372 0.000
H02.2 Lagophthalmos
0.628 0.372 0.000
M48 Other spondylopathies
0.628 0.372 0.000
D67 Hereditary factor IX deficiency
0.627 0.372 0.000
D66 Hereditary factor VIII deficiency
0.627 0.372 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.627 0.372 0.000
A49.8 Other bacterial infections of unspecified site
0.627 0.373 0.000
H60.8 Other otitis externa
0.627 0.373 0.000
H60.5 Acute otitis externa, non-infective
0.627 0.373 0.000
H60.4 Cholesteatoma of external ear
0.627 0.373 0.000
H60.3 Other infective otitis externa
0.627 0.373 0.000
H60.2 Malignant otitis externa
0.627 0.373 0.000
H60.0 Abscess of external ear
0.627 0.373 0.000
M79.18 Myalgia (Other)
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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