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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117559199
log Bayes Factor = 8.42044
Chromosome 12   position 75,424,551  (GRCh37) Explore rs117559199 on Ensembl!
Variant rs117559199 is part of Cluster X0171

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I35 Nonrheumatic aortic valve disorders
0.993 0.007 0.000
I34 Nonrheumatic mitral valve disorders
0.992 0.008 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
M20-M25 Other joint disorders
0.987 0.013 0.000
O48 Prolonged pregnancy
0.981 0.019 0.000
I34.0 Mitral (valve) insufficiency
0.979 0.021 0.000
M25 Other joint disorders, not elsewhere classified
0.978 0.022 0.000
I35.1 Aortic (valve) insufficiency
0.976 0.024 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.969 0.031 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.969 0.031 0.000
M25.5 Pain in joint
0.968 0.032 0.000
S00-S09 Injuries to the head
0.967 0.033 0.000
S50-S59 Injuries to the elbow and forearm
0.952 0.048 0.000
S70-S79 Injuries to the hip and thigh
0.950 0.050 0.000
S00 Superficial injury of head
0.945 0.055 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.945 0.055 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.937 0.063 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.934 0.066 0.000
M31 Other necrotising vasculopathies
0.934 0.066 0.000
O60-O75 Complications of labour and delivery
0.933 0.067 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.930 0.070 0.000
M65-M68 Disorders of synovium and tendon
0.928 0.072 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.925 0.075 0.000
D69 Purpura and other haemorrhagic conditions
0.920 0.080 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.915 0.085 0.000
D60-D64 Aplastic and other anaemias
0.912 0.088 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.908 0.092 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.905 0.095 0.000
I98.2 Oesophageal varices in diseases classified elsewhere
0.902 0.098 0.000
M70-M79 Other soft tissue disorders
0.901 0.099 0.000
O40 Polyhydramnios
0.900 0.100 0.000
S20-S29 Injuries to the thorax
0.897 0.103 0.000
S72 Fracture of femur
0.896 0.104 0.000
S60-S69 Injuries to the wrist and hand
0.890 0.110 0.000
S52 Fracture of forearm
0.886 0.114 0.000
I35.9 Aortic valve disorder, unspecified
0.886 0.114 0.000
O30 Multiple gestation
0.878 0.122 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.873 0.127 0.000
D69.6 Thrombocytopenia, unspecified
0.872 0.128 0.000
O36 Maternal care for other known or suspected foetal problems
0.872 0.128 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.872 0.128 0.000
M31.3 Wegener's granulomatosis
0.871 0.129 0.000
I50 Heart failure
0.870 0.130 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.867 0.133 0.000
M65 Synovitis and tenosynovitis
0.865 0.135 0.000
M40-M43 Deforming dorsopathies
0.861 0.139 0.000
O70 Perineal laceration during delivery
0.860 0.140 0.000
O62 Abnormalities of forces of labour
0.849 0.151 0.000
M80-M85 Disorders of bone density and structure
0.847 0.153 0.000
O80-O84 Delivery
0.847 0.153 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.847 0.153 0.000
S00.9 Superficial injury of head, part unspecified
0.839 0.161 0.000
I50.0 Congestive heart failure
0.836 0.164 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.835 0.165 0.000
S00.1 Contusion of eyelid and periocular area
0.834 0.166 0.000
I73 Other peripheral vascular diseases
0.834 0.166 0.000
Chapter II Neoplasms
0.833 0.167 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.833 0.167 0.000
D62 Acute posthaemorrhagic anaemia
0.828 0.172 0.000
M25.52 Pain in joint (Upper arm)
0.824 0.176 0.000
I35.8 Other aortic valve disorders
0.824 0.176 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.821 0.179 0.000
S80-S89 Injuries to the knee and lower leg
0.821 0.179 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.820 0.180 0.000
S40-S49 Injuries to the shoulder and upper arm
0.816 0.184 0.000
M25.59 Pain in joint (Site unspecified)
0.815 0.185 0.000
T79-T79 Certain early complications of trauma
0.813 0.187 0.000
M50-M54 Other dorsopathies
0.813 0.187 0.000
M25.51 Pain in joint (Shoulder region)
0.812 0.188 0.000
I35.0 Aortic (valve) stenosis
0.812 0.188 0.000
S64 Injury of nerves at wrist and hand level
0.810 0.190 0.000
S90-S99 Injuries to the ankle and foot
0.808 0.191 0.000
S52.1 Fracture of upper end of radius
0.808 0.192 0.000
I77 Other disorders of arteries and arterioles
0.808 0.192 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.808 0.192 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.806 0.194 0.000
M25.56 Pain in joint (Lower leg)
0.802 0.198 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.800 0.200 0.000
I73.0 Raynaud's syndrome
0.800 0.200 0.000
O70.1 Second degree perineal laceration during delivery
0.799 0.201 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.799 0.201 0.000
I42 Cardiomyopathy
0.797 0.203 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.797 0.203 0.000
O35.8 Maternal care for other (suspected) foetal abnormality and damage
0.796 0.204 0.000
Y52 Agents primarily affecting the cardiovascular system
0.794 0.206 0.000
O35.1 Maternal care for (suspected) chromosomal abnormality in foetus
0.794 0.206 0.000
O30.0 Twin pregnancy
0.792 0.208 0.000
M72 Fibroblastic disorders
0.790 0.210 0.000
X60-X84 Intentional self-harm
0.789 0.211 0.000
Y95 Nosocomial condition
0.787 0.213 0.000
M79.6 Pain in limb
0.786 0.214 0.000
W50-W64 Exposure to animate mechanical forces
0.786 0.214 0.000
S68 Traumatic amputation of wrist and hand
0.786 0.214 0.000
O34.1 Maternal care for tumour of corpus uteri
0.785 0.215 0.000
M21 Other acquired deformities of limbs
0.784 0.216 0.000
I34.1 Mitral (valve) prolapse
0.784 0.216 0.000
M05-M14 Inflammatory polyarthropathies
0.784 0.216 0.000
D00-D09 In situ neoplasms
0.784 0.216 0.000
W00-W19 Falls
0.781 0.219 0.000
M86-M90 Other osteopathies
0.780 0.220 0.000
V40-V49 Car occupant injured in transport accident
0.780 0.220 0.000
M25.50 Pain in joint (Multiple sites)
0.779 0.221 0.000
O36.0 Maternal care for rhesus isoimmunisation
0.779 0.221 0.000
M00-M03 Infectious arthropathies
0.779 0.221 0.000
M54 Dorsalgia
0.775 0.225 0.000
S72.1 Pertrochanteric fracture
0.775 0.225 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.771 0.228 0.000
M25.3 Other instability of joint
0.771 0.229 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.770 0.230 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.769 0.231 0.000
O35.9 Maternal care for (suspected) foetal abnormality and damage, unspecified
0.767 0.233 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.767 0.233 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.765 0.235 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.765 0.235 0.000
D69.9 Haemorrhagic condition, unspecified
0.764 0.236 0.000
O73 Retained placenta and membranes, without haemorrhage
0.764 0.236 0.000
I46 Cardiac arrest
0.764 0.236 0.000
O62.2 Other uterine inertia
0.763 0.237 0.000
S02 Fracture of skull and facial bones
0.762 0.238 0.000
S20 Superficial injury of thorax
0.761 0.239 0.000
S00.8 Superficial injury of other parts of head
0.761 0.239 0.000
M30 Polyarteritis nodosa and related conditions
0.760 0.240 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.760 0.240 0.000
V80-V89 Other land transport accidents
0.760 0.240 0.000
M25.8 Other specified joint disorders
0.759 0.241 0.000
M25.4 Effusion of joint
0.757 0.243 0.000
S64.4 Injury of digital nerve of other finger
0.757 0.243 0.000
S72.3 Fracture of shaft of femur
0.757 0.243 0.000
W20-W49 Exposure to inanimate mechanical forces
0.756 0.244 0.000
S52.0 Fracture of upper end of ulna
0.755 0.245 0.000
I99 Other and unspecified disorders of circulatory system
0.755 0.245 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.754 0.246 0.000
S52.10 Fracture of upper end of radius (closed)
0.753 0.247 0.000
S56 Injury of muscle and tendon at forearm level
0.753 0.247 0.000
I05-I09 Chronic rheumatic heart diseases
0.751 0.249 0.000
S80 Superficial injury of lower leg
0.749 0.251 0.000
M31.5 Giant cell arteritis with polymyalgia rheumatica
0.746 0.254 0.000
S71 Open wound of hip and thigh
0.744 0.255 0.000
I36 Nonrheumatic tricuspid valve disorders
0.744 0.256 0.000
T18 Foreign body in alimentary tract
0.743 0.257 0.000
M24 Other specific joint derangements
0.743 0.257 0.000
Y00-Y09 Assault
0.742 0.258 0.000
O44 Placenta praevia
0.742 0.258 0.000
M25.0 Haemarthrosis
0.741 0.259 0.000
S00.7 Multiple superficial injuries of head
0.738 0.262 0.000
M65.8 Other synovitis and tenosynovitis
0.738 0.262 0.000
I33 Acute and subacute endocarditis
0.737 0.263 0.000
O85-O92 Complications predominantly related to the puerperium
0.735 0.265 0.000
O80 Single spontaneous delivery
0.735 0.265 0.000
I30 Acute pericarditis
0.735 0.265 0.000
O43 Placental disorders
0.734 0.266 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.731 0.269 0.000
Y40 Systemic antibiotics
0.731 0.269 0.000
I97.2 Postmastectomy lymphoedema syndrome
0.730 0.270 0.000
M72.0 Palmar fascial fibromatosis [Dupuytren]
0.730 0.270 0.000
S51 Open wound of forearm
0.730 0.270 0.000
M65.3 Trigger finger
0.729 0.271 0.000
X50-X57 Overexertion, travel and privation
0.729 0.271 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.725 0.275 0.000
I49 Other cardiac arrhythmias
0.724 0.276 0.000
T66-T78 Other and unspecified effects of external causes
0.723 0.276 0.000
Q80-Q89 Other congenital malformations
0.723 0.277 0.000
S65 Injury of blood vessels at wrist and hand level
0.723 0.277 0.000
M60-M63 Disorders of muscles
0.720 0.279 0.000
M25.9 Joint disorder, unspecified
0.720 0.280 0.000
S50 Superficial injury of forearm
0.719 0.281 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
D05 Carcinoma in situ of breast
0.717 0.283 0.000
I85 Oesophageal varices
0.717 0.283 0.000
Y48 Anaesthetics and therapeutic gases
0.717 0.283 0.000
O45 Premature separation of placenta [abruptio placentae]
0.717 0.283 0.000
O33 Maternal care for known or suspected disproportion
0.717 0.283 0.000
O31 Complications specific to multiple gestation
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
D63.0 Anaemia in neoplastic disease
0.714 0.286 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.714 0.286 0.000
M43 Other deforming dorsopathies
0.712 0.288 0.000
I34.8 Other nonrheumatic mitral valve disorders
0.711 0.289 0.000
M67 Other disorders of synovium and tendon
0.711 0.289 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.711 0.289 0.000
O72 Postpartum haemorrhage
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X10-X19 Contact with heat and hot substances
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.708 0.292 0.000
M33 Dermatopolymyositis
0.708 0.292 0.000
M32 Systemic lupus erythematosus
0.708 0.292 0.000
M31.6 Other giant cell arteritis
0.707 0.293 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.707 0.293 0.000
V20-V29 Motorcycle rider injured in transport accident
0.707 0.293 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.706 0.294 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.706 0.294 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.705 0.295 0.000
Q50-Q56 Congenital malformations of genital organs
0.704 0.296 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.704 0.296 0.000
O41 Other disorders of amniotic fluid and membranes
0.703 0.297 0.000
S70 Superficial injury of hip and thigh
0.702 0.298 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.702 0.298 0.000
M25.2 Flail joint
0.701 0.298 0.000
M25.1 Fistula of joint
0.701 0.298 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.700 0.300 0.000
I77.6 Arteritis, unspecified
0.699 0.301 0.000
S41 Open wound of shoulder and upper arm
0.699 0.301 0.000
X20-X29 Contact with venomous animals and plants
0.699 0.301 0.000
M41 Scoliosis
0.699 0.301 0.000
M34 Systemic sclerosis
0.698 0.301 0.000
T17 Foreign body in respiratory tract
0.698 0.302 0.000
M05 Seropositive rheumatoid arthritis
0.696 0.304 0.000
S72.2 Subtrochanteric fracture
0.695 0.305 0.000
M22 Disorders of patella
0.695 0.305 0.000
O36.6 Maternal care for excessive foetal growth
0.695 0.305 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.694 0.306 0.000
M25.58 Pain in joint (Other)
0.694 0.306 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.694 0.306 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.693 0.307 0.000
S79 Other and unspecified injuries of hip and thigh
0.692 0.307 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.692 0.308 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
D55-D59 Haemolytic anaemias
0.691 0.309 0.000
S52.7 Multiple fractures of forearm
0.691 0.309 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.689 0.311 0.000
S27 Injury of other and unspecified intrathoracic organs
0.689 0.311 0.000
S72.4 Fracture of lower end of femur
0.688 0.312 0.000
O70.9 Perineal laceration during delivery, unspecified
0.688 0.312 0.000
S72.10 Pertrochanteric fracture (closed)
0.687 0.313 0.000
M72.04 Palmar fascial fibromatosis [Dupuytren]-Hand
0.687 0.313 0.000
M54.1 Radiculopathy
0.687 0.313 0.000
S05 Injury of eye and orbit
0.684 0.315 0.000
M77 Other enthesopathies
0.684 0.316 0.000
M85 Other disorders of bone density and structure
0.684 0.316 0.000
O36.5 Maternal care for poor foetal growth
0.684 0.316 0.000
M91-M94 Chondropathies
0.683 0.317 0.000
Q60-Q64 Congenital malformations of the urinary system
0.683 0.317 0.000
M06 Other rheumatoid arthritis
0.683 0.317 0.000
M54.5 Low back pain
0.683 0.317 0.000
S59 Other and unspecified injuries of forearm
0.682 0.318 0.000
S58 Traumatic amputation of forearm
0.682 0.318 0.000
S57 Crushing injury of forearm
0.682 0.318 0.000
S55 Injury of blood vessels at forearm level
0.682 0.318 0.000
S54 Injury of nerves at forearm level
0.682 0.318 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.682 0.318 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.682 0.318 0.000
S78 Traumatic amputation of hip and thigh
0.681 0.319 0.000
S77 Crushing injury of hip and thigh
0.681 0.319 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.681 0.319 0.000
S75 Injury of blood vessels at hip and thigh level
0.681 0.319 0.000
S74 Injury of nerves at hip and thigh level
0.681 0.319 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.681 0.319 0.000
S60 Superficial injury of wrist and hand
0.680 0.320 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.680 0.320 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.679 0.321 0.000
Y43 Primarily systemic agents
0.679 0.321 0.000
S10-S19 Injuries to the neck
0.678 0.322 0.000
S00.5 Superficial injury of lip and oral cavity
0.678 0.322 0.000
S00.4 Superficial injury of ear
0.678 0.322 0.000
S01 Open wound of head
0.677 0.323 0.000
O16 Unspecified maternal hypertension
0.677 0.323 0.000
O71 Other obstetric trauma
0.676 0.324 0.000
Chapter XXII Codes for special purposes
0.675 0.325 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.674 0.326 0.000
Y65 Other misadventures during surgical and medical care
0.673 0.327 0.000
S72.0 Fracture of neck of femur
0.673 0.327 0.000
S66.8 Injury of other muscles and tendons at wrist and hand level
0.673 0.327 0.000
I74 Arterial embolism and thrombosis
0.673 0.327 0.000
I70 Atherosclerosis
0.672 0.328 0.000
D67 Hereditary factor IX deficiency
0.672 0.328 0.000
D66 Hereditary factor VIII deficiency
0.672 0.328 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.672 0.328 0.000
O62.4 Hypertonic, incoordinate and prolonged uterine contractions
0.672 0.328 0.000
S29 Other and unspecified injuries of thorax
0.672 0.328 0.000
O61 Failed induction of labour
0.671 0.329 0.000
I42.9 Cardiomyopathy, unspecified
0.671 0.329 0.000
C64-C68 Malignant neoplasms of urinary tract
0.670 0.330 0.000
S91 Open wound of ankle and foot
0.670 0.330 0.000
O35.7 Maternal care for (suspected) damage to foetus by other medical procedures
0.670 0.330 0.000
O35.6 Maternal care for (suspected) damage to foetus by radiation
0.670 0.330 0.000
O35.5 Maternal care for (suspected) damage to foetus by drugs
0.670 0.330 0.000
O35.4 Maternal care for (suspected) damage to foetus from alcohol
0.670 0.330 0.000
O35.3 Maternal care for (suspected) damage to foetus from viral disease in mother
0.670 0.330 0.000
O35.2 Maternal care for (suspected) hereditary disease in foetus
0.670 0.330 0.000
O35.0 Maternal care for (suspected) central nervous system malformation in foetus
0.670 0.330 0.000
M31.9 Necrotising vasculopathy, unspecified
0.669 0.330 0.000
M31.8 Other specified necrotising vasculopathies
0.669 0.330 0.000
M31.7 Microscopic polyangiitis
0.669 0.330 0.000
M31.4 Aortic arch syndrome [Takayasu]
0.669 0.330 0.000
M31.2 Lethal midline granuloma
0.669 0.330 0.000
M31.1 Thrombotic microangiopathy
0.669 0.330 0.000
M31.0 Hypersensitivity angiitis
0.669 0.330 0.000
O74 Complications of anaesthesia during labour and delivery
0.669 0.331 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.669 0.331 0.000
O60 Preterm delivery
0.669 0.331 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.668 0.332 0.000
I98.8 Other specified disorders of circulatory system in diseases classified elsewhere
0.667 0.333 0.000
I98.3 Oesophageal varices with bleeding in diseases classified elsewhere
0.667 0.333 0.000
I98.1 Cardiovascular disorders in other infectious and parasitic diseases classified elsewhere
0.667 0.333 0.000
I98.0 Cardiovascular syphilis
0.667 0.333 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.667 0.333 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.665 0.335 0.000
M66 Spontaneous rupture of synovium and tendon
0.665 0.335 0.000
O63 Long labour
0.665 0.335 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.664 0.336 0.000
Q00-Q07 Congenital malformations of the nervous system
0.664 0.336 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.664 0.336 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.662 0.338 0.000
M79.62 Pain in limb (Upper arm)
0.662 0.338 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.661 0.339 0.000
S52.00 Fracture of upper end of ulna (closed)
0.661 0.339 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.660 0.340 0.000
D69.8 Other specified haemorrhagic conditions
0.659 0.341 0.000
D69.4 Other primary thrombocytopenia
0.659 0.341 0.000
D69.2 Other nonthrombocytopenic purpura
0.659 0.341 0.000
D69.1 Qualitative platelet defects
0.659 0.341 0.000
D69.0 Allergic purpura
0.659 0.341 0.000
M76 Enthesopathies of lower limb, excluding foot
0.659 0.341 0.000
S00.3 Superficial injury of nose
0.659 0.341 0.000
D61 Other aplastic anaemias
0.658 0.342 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.657 0.343 0.000
I85.9 Oesophageal varices without bleeding
0.657 0.343 0.000
S72.30 Fracture of shaft of femur (closed)
0.657 0.343 0.000
O47 False labour
0.657 0.343 0.000
M79.7 Fibromyalgia
0.656 0.344 0.000
Y59 Other and unspecified vaccines and biological substances
0.656 0.344 0.000
Y58 Bacterial vaccines
0.656 0.344 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.656 0.344 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.656 0.344 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.656 0.344 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.656 0.344 0.000
O70.2 Third degree perineal laceration during delivery
0.656 0.344 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.655 0.345 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.654 0.346 0.000
S52.8 Fracture of other parts of forearm
0.651 0.349 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.651 0.349 0.000
Q35-Q37 Cleft lip and cleft palate
0.651 0.349 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.651 0.349 0.000
S00.0 Superficial injury of scalp
0.651 0.349 0.000
M71 Other bursopathies
0.650 0.349 0.000
D69.5 Secondary thrombocytopenia
0.650 0.350 0.000
M96.1 Postlaminectomy syndrome, not elsewhere classified
0.650 0.350 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.650 0.350 0.000
D05.1 Intraductal carcinoma in situ
0.650 0.350 0.000
S06 Intracranial injury
0.650 0.350 0.000
O34.9 Maternal care for abnormality of pelvic organ, unspecified
0.649 0.351 0.000
O34.8 Maternal care for other abnormalities of pelvic organs
0.649 0.351 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.649 0.351 0.000
O34.6 Maternal care for abnormality of vagina
0.649 0.351 0.000
O34.5 Maternal care for other abnormalities of gravid uterus
0.649 0.351 0.000
O34.4 Maternal care for other abnormalities of cervix
0.649 0.351 0.000
O34.3 Maternal care for cervical incompetence
0.649 0.351 0.000
O34.0 Maternal care for congenital malformation of uterus
0.649 0.351 0.000
O66 Other obstructed labour
0.649 0.351 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.648 0.352 0.000
M84 Disorders of continuity of bone
0.647 0.353 0.000
I44 Atrioventricular and left bundle-branch block
0.646 0.354 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.646 0.354 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.646 0.354 0.000
W51 Striking against or bumped into by another person
0.645 0.354 0.000
M79.66 Pain in limb (Lower leg)
0.644 0.356 0.000
M79.0 Rheumatism, unspecified
0.644 0.356 0.000
I71 Aortic aneurysm and dissection
0.644 0.356 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.643 0.357 0.000
S26 Injury of heart
0.643 0.357 0.000
S25 Injury of blood vessels of thorax
0.643 0.357 0.000
S24 Injury of nerves and spinal cord at thorax level
0.643 0.357 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.643 0.357 0.000
S21 Open wound of thorax
0.643 0.357 0.000
S20.1 Other and unspecified superficial injuries of breast
0.643 0.357 0.000
S72.9 Fracture of femur, part unspecified
0.643 0.357 0.000
S72.8 Fractures of other parts of femur
0.643 0.357 0.000
S72.7 Multiple fractures of femur
0.643 0.357 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.642 0.358 0.000
M80 Osteoporosis with pathological fracture
0.642 0.358 0.000
S09 Other and unspecified injuries of head
0.642 0.358 0.000
O73.0 Retained placenta, without haemorrhage
0.642 0.358 0.000
M54.4 Lumbago with sciatica
0.641 0.359 0.000
V10-V19 Pedal cyclist injured in transport accident
0.641 0.359 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.640 0.360 0.000
Y57 Other and unspecified drugs and medicaments
0.640 0.360 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.639 0.361 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.639 0.361 0.000
D47.3 Essential (haemorrhagic) thrombocythaemia
0.639 0.361 0.000
I49.9 Cardiac arrhythmia, unspecified
0.639 0.361 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.637 0.363 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.637 0.363 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.636 0.364 0.000
S02.5 Fracture of tooth
0.635 0.364 0.000
S52.9 Fracture of forearm, part unspecified
0.635 0.365 0.000
S52.4 Fracture of shafts of both ulna and radius
0.635 0.365 0.000
S52.3 Fracture of shaft of radius
0.635 0.365 0.000
S52.2 Fracture of shaft of ulna
0.635 0.365 0.000
T20 Burn and corrosion of head and neck
0.635 0.365 0.000
M25.47 Effusion of joint (Ankle and foot)
0.635 0.365 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.634 0.365 0.000
Y44 Agents primarily affecting blood constituents
0.634 0.366 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.633 0.367 0.000
D04 Carcinoma in situ of skin
0.632 0.368 0.000
Chapter V Mental and behavioural disorders
0.632 0.368 0.000
M65.34 Trigger finger-Hand
0.632 0.368 0.000
S80.9 Superficial injury of lower leg, unspecified
0.631 0.369 0.000
C43 Malignant melanoma of skin
0.631 0.369 0.000
O81 Single delivery by forceps and vacuum extractor
0.630 0.370 0.000
M45-M49 Spondylopathies
0.630 0.370 0.000
Y45.0 Opioids and related analgesics
0.630 0.370 0.000
O30.9 Multiple gestation, unspecified
0.630 0.370 0.000
O30.8 Other multiple gestation
0.630 0.370 0.000
O30.2 Quadruplet pregnancy
0.630 0.370 0.000
O30.1 Triplet pregnancy
0.630 0.370 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.630 0.370 0.000
W10 Fall on and from stairs and steps
0.630 0.370 0.000
O36.8 Maternal care for other specified foetal problems
0.629 0.371 0.000
W08 Fall involving other furniture
0.629 0.371 0.000
O80.0 Spontaneous vertex delivery
0.629 0.371 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.629 0.371 0.000
S80.0 Contusion of knee
0.629 0.371 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.629 0.371 0.000
D09 Carcinoma in situ of other and unspecified sites
0.629 0.371 0.000
M54.9 Dorsalgia, unspecified
0.628 0.372 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.627 0.372 0.000
T18.9 Foreign body in alimentary tract, part unspecified
0.627 0.373 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.627 0.373 0.000
M79.2 Neuralgia and neuritis, unspecified
0.627 0.373 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.626 0.374 0.000
I78 Diseases of capillaries
0.626 0.374 0.000
T19 Foreign body in genito-urinary tract
0.626 0.374 0.000
T15 Foreign body on external eye
0.626 0.374 0.000
T16 Foreign body in ear
0.626 0.374 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.625 0.375 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.625 0.375 0.000
O36.4 Maternal care for intra-uterine death
0.625 0.375 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.625 0.375 0.000
O36.2 Maternal care for hydrops foetalis
0.625 0.375 0.000
O36.1 Maternal care for other isoimmunisation
0.625 0.375 0.000
Y91 Evidence of alcohol involvement determined by level of intoxication
0.625 0.375 0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level
0.625 0.375 0.000
Y98 Lifestyle-related condition
0.625 0.375 0.000
Y97 Environmental-pollution-related condition
0.625 0.375 0.000
Y96 Work-related condition
0.625 0.375 0.000
X47 Accidental poisoning by and exposure to other gases and vapours
0.624 0.376 0.000
C71 Malignant neoplasm of brain
0.624 0.376 0.000
M81 Osteoporosis without pathological fracture
0.623 0.377 0.000
C51-C58 Malignant neoplasms of female genital organs
0.623 0.377 0.000
M99 Biomechanical lesions, not elsewhere classified
0.622 0.378 0.000
M25.31 Other instability of joint (Shoulder region)
0.622 0.378 0.000
M65.2 Calcific tendinitis
0.620 0.379 0.000
M65.1 Other infective (teno)synovitis
0.620 0.379 0.000
M65.0 Abscess of tendon sheath
0.620 0.379 0.000
M00 Pyogenic arthritis
0.620 0.380 0.000
S02.3 Fracture of orbital floor
0.620 0.380 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.619 0.380 0.000
M54.57 Low back pain (Lumbosacral region)
0.619 0.381 0.000
M25.7 Osteophyte
0.618 0.382 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.618 0.382 0.000
O62.0 Primary inadequate contractions
0.618 0.382 0.000
I42.6 Alcoholic cardiomyopathy
0.617 0.382 0.000
M25.85 Other specified joint disorders (Pelvic region and thigh)
0.617 0.383 0.000
M42 Spinal osteochondrosis
0.617 0.383 0.000
M40 Kyphosis and lordosis
0.617 0.383 0.000
I97.1 Other functional disturbances following cardiac surgery
0.617 0.383 0.000
O70.3 Fourth degree perineal laceration during delivery
0.617 0.383 0.000
I72 Other aneurysm
0.616 0.384 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.616 0.384 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.615 0.385 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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