TreeWAS – Variant ID: rs11758945

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Chapter XX External causes of morbidity and mortality	0.997	0.003
Chapter IX Diseases of the circulatory system	0.992	0.008
Chapter XV Pregnancy, childbirth and the puerperium	0.990	0.010
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.988	0.012
S00-S09 Injuries to the head	0.987	0.013
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.976	0.024
S09 Other and unspecified injuries of head	0.967	0.033
Chapter VI Diseases of the nervous system	0.966	0.034
I30-I52 Other forms of heart disease	0.963	0.037
I35 Nonrheumatic aortic valve disorders	0.956	0.044
I10-I15 Hypertensive diseases	0.955	0.045
S80-S89 Injuries to the knee and lower leg	0.952	0.048
S09.9 Unspecified injury of head	0.952	0.048
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.947	0.053
I10 Essential (primary) hypertension	0.940	0.060
S70-S79 Injuries to the hip and thigh	0.938	0.062
O20-O29 Other maternal disorders predominantly related to pregnancy	0.937	0.063
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.934	0.066
I35.2 Aortic (valve) stenosis with insufficiency	0.932	0.068
Chapter I Certain infectious and parasitic diseases	0.929	0.071
S90-S99 Injuries to the ankle and foot	0.928	0.072
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.912	0.088
S40-S49 Injuries to the shoulder and upper arm	0.910	0.090
G20-G26 Extrapyramidal and movement disorders	0.909	0.091
Chapter XXII Codes for special purposes	0.907	0.093
Chapter II Neoplasms	0.902	0.098
Y57 Other and unspecified drugs and medicaments	0.900	0.100
G35-G37 Demyelinating diseases of the central nervous system	0.892	0.108
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.891	0.109
S50-S59 Injuries to the elbow and forearm	0.890	0.110
O94-O99 Other obstetric conditions, not elsewhere classified	0.886	0.114
S02 Fracture of skull and facial bones	0.885	0.115
B15-B19 Viral hepatitis	0.881	0.119
O42 Premature rupture of membranes	0.880	0.120
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.877	0.123
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.873	0.127
O47 False labour	0.869	0.131
Y52 Agents primarily affecting the cardiovascular system	0.866	0.134
O48 Prolonged pregnancy	0.863	0.137
I27 Other pulmonary heart diseases	0.861	0.139
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.859	0.141
I70-I79 Diseases of arteries, arterioles and capillaries	0.857	0.143
S82 Fracture of lower leg, including ankle	0.855	0.145
S72 Fracture of femur	0.855	0.145
S10-S19 Injuries to the neck	0.854	0.146
S80 Superficial injury of lower leg	0.854	0.146
I35.1 Aortic (valve) insufficiency	0.854	0.146
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.852	0.148
M86-M90 Other osteopathies	0.849	0.151
M50-M54 Other dorsopathies	0.844	0.156
I34 Nonrheumatic mitral valve disorders	0.835	0.165
G00-G09 Inflammatory diseases of the central nervous system	0.831	0.169
B18 Chronic viral hepatitis	0.830	0.170
I38 Endocarditis, valve unspecified	0.826	0.174
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.823	0.177
T79-T79 Certain early complications of trauma	0.822	0.178
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.820	0.180
G25 Other extrapyramidal and movement disorders	0.820	0.180
O24 Diabetes mellitus in pregnancy	0.819	0.181
Chapter V Mental and behavioural disorders	0.818	0.182
Y40 Systemic antibiotics	0.817	0.183
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.817	0.183
I35.8 Other aortic valve disorders	0.815	0.185
C15-C26 Malignant neoplasms of digestive organs	0.814	0.186
M80-M85 Disorders of bone density and structure	0.813	0.187
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.812	0.188
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.812	0.188
S72.0 Fracture of neck of femur	0.812	0.188
Chapter IV Endocrine, nutritional and metabolic diseases	0.812	0.188
O40 Polyhydramnios	0.811	0.189
M60-M63 Disorders of muscles	0.810	0.190
M40-M43 Deforming dorsopathies	0.809	0.191
S90 Superficial injury of ankle and foot	0.809	0.191
C77.2 Intra-abdominal lymph nodes	0.808	0.192
G35 Multiple sclerosis	0.807	0.193
S91 Open wound of ankle and foot	0.807	0.193
S81 Open wound of lower leg	0.807	0.193
Chapter XII Diseases of the skin and subcutaneous tissue	0.805	0.195
O26 Maternal care for other conditions predominantly related to pregnancy	0.805	0.195
G90-G99 Other disorders of the nervous system	0.805	0.195
G30-G32 Other degenerative diseases of the nervous system	0.804	0.196
G80-G83 Cerebral palsy and other paralytic syndromes	0.802	0.198
V20-V29 Motorcycle rider injured in transport accident	0.802	0.198
I95-I99 Other and unspecified disorders of the circulatory system	0.801	0.199
B07 Viral warts	0.801	0.199
I34.1 Mitral (valve) prolapse	0.799	0.201
L60-L75 Disorders of skin appendages	0.796	0.204
T80 Complications following infusion, transfusion and therapeutic injection	0.795	0.205
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.795	0.205
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.789	0.211
S02.3 Fracture of orbital floor	0.789	0.211
W00-W19 Falls	0.786	0.214
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.785	0.215
I47 Paroxysmal tachycardia	0.785	0.215
S52 Fracture of forearm	0.785	0.215
M54 Dorsalgia	0.783	0.217
G24 Dystonia	0.782	0.218
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.782	0.218
S72.00 Fracture of neck of femur (closed)	0.781	0.219
Y49 Psychotropic drugs, not elsewhere classified	0.781	0.219
S05 Injury of eye and orbit	0.780	0.220
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.780	0.220
Y57.8 Other drugs and medicaments	0.778	0.222
T88 Other complications of surgical and medical care, not elsewhere classified	0.778	0.222
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.774	0.225
I37 Pulmonary valve disorders	0.772	0.228
O21 Excessive vomiting in pregnancy	0.772	0.228
L60 Nail disorders	0.771	0.229
S41 Open wound of shoulder and upper arm	0.767	0.233
M89 Other disorders of bone	0.766	0.234
S42 Fracture of shoulder and upper arm	0.766	0.234
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.765	0.235
B18.2 Chronic viral hepatitis C	0.764	0.236
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium	0.761	0.239
T86 Failure and rejection of transplanted organs and tissues	0.761	0.239
Y53 Agents primarily affecting the gastro-intestinal system	0.761	0.239
S02.4 Fracture of malar and maxillary bones	0.761	0.239
O47.0 False labour before 37 completed weeks of gestation	0.760	0.240
O43 Placental disorders	0.760	0.240
S00 Superficial injury of head	0.760	0.240
Y57.5 X-ray contrast media	0.758	0.242
S71 Open wound of hip and thigh	0.757	0.243
I27.9 Pulmonary heart disease, unspecified	0.757	0.243
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.756	0.244
I26 Pulmonary embolism	0.756	0.244
S70 Superficial injury of hip and thigh	0.755	0.245
T66-T78 Other and unspecified effects of external causes	0.753	0.247
C77.8 Lymph nodes of multiple regions	0.752	0.248
I27.2 Other secondary pulmonary hypertension	0.752	0.248
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.748	0.251
O42.1 Premature rupture of membranes, onset of labour after 24 hours	0.747	0.253
Y52.2 Other antidysrhythmic drugs, not elsewhere classified	0.746	0.253
O35 Maternal care for known or suspected foetal abnormality and damage	0.746	0.254
S92 Fracture of foot, except ankle	0.745	0.255
S46 Injury of muscle and tendon at shoulder and upper arm level	0.744	0.256
S02.5 Fracture of tooth	0.744	0.256
D00-D09 In situ neoplasms	0.743	0.257
S82.0 Fracture of patella	0.743	0.257
S82.3 Fracture of lower end of tibia	0.741	0.259
O45 Premature separation of placenta [abruptio placentae]	0.740	0.260
C77.3 Axillary and upper limb lymph nodes	0.740	0.260
S82.5 Fracture of medial malleolus	0.739	0.261
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.739	0.261
W50-W64 Exposure to animate mechanical forces	0.738	0.261
X60-X84 Intentional self-harm	0.738	0.262
V80-V89 Other land transport accidents	0.738	0.262
S52.5 Fracture of lower end of radius	0.737	0.263
T00-T07 Injuries involving multiple body regions	0.736	0.264
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.736	0.264
G37 Other demyelinating diseases of central nervous system	0.736	0.264
X20-X29 Contact with venomous animals and plants	0.734	0.266
M00-M03 Infectious arthropathies	0.734	0.266
G25.0 Essential tremor	0.733	0.267
O23 Infections of genito-urinary tract in pregnancy	0.732	0.268
Y46 Antiepileptics and anti-Parkinsonism drugs	0.731	0.268
S80.9 Superficial injury of lower leg, unspecified	0.731	0.269
O30 Multiple gestation	0.729	0.271
O34 Maternal care for known or suspected abnormality of pelvic organs	0.728	0.272
L73 Other follicular disorders	0.728	0.272
T20-T25 Burns and corrosions of external body surface, specified by site	0.727	0.273
V10-V19 Pedal cyclist injured in transport accident	0.726	0.274
E20-E35 Disorders of other endocrine glands	0.726	0.274
I35.0 Aortic (valve) stenosis	0.725	0.275
V40-V49 Car occupant injured in transport accident	0.724	0.275
M84 Disorders of continuity of bone	0.723	0.277
X50-X57 Overexertion, travel and privation	0.723	0.277
S90.9 Superficial injury of ankle and foot, unspecified	0.723	0.277
I47.2 Ventricular tachycardia	0.723	0.277
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.722	0.278
O24.4 Diabetes mellitus arising in pregnancy	0.721	0.279
S02.30 Fracture of orbital floor (closed)	0.720	0.280
S91.3 Open wound of other parts of foot	0.720	0.280
A50-A64 Infections with a predominantly sexual mode of transmission	0.720	0.280
C18 Malignant neoplasm of colon	0.720	0.280
Y40.8 Other systemic antibiotics	0.720	0.280
T36-T50 Poisoning by drugs, medicaments and biological substances	0.719	0.281
O85-O92 Complications predominantly related to the puerperium	0.719	0.281
S19 Other and unspecified injuries of neck	0.719	0.281
G90 Disorders of autonomic nervous system	0.718	0.282
S51 Open wound of forearm	0.718	0.282
X58-X59 Accidental exposure to other and unspecified factors	0.717	0.282
T85 Complications of other internal prosthetic devices, implants and grafts	0.717	0.283
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
C80 Malignant neoplasm without specification of site	0.717	0.283
Y35-Y36 Legal intervention and operations of war	0.715	0.285
Y10-Y34 Event of undetermined intent	0.715	0.285
Y00-Y09 Assault	0.715	0.285
X85-X99 Assault	0.715	0.285
X30-X39 Exposure to forces of nature	0.715	0.285
X10-X19 Contact with heat and hot substances	0.715	0.285
X00-X09 Exposure to smoke, fire and flames	0.715	0.285
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.715	0.285
W75-W84 Other accidental threats to breathing	0.715	0.285
W65-W74 Accidental drowning and submersion	0.715	0.285
V98-V99 Other and unspecified transport accidents	0.715	0.285
V95-V97 Air and space transport accidents	0.715	0.285
V90-V94 Water transport accidents	0.715	0.285
V70-V79 Bus occupant injured in transport accident	0.715	0.285
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.715	0.285
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.715	0.285
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.715	0.285
V01-V09 Pedestrian injured in transport accident	0.715	0.285
I33 Acute and subacute endocarditis	0.715	0.285
I28 Other diseases of pulmonary vessels	0.715	0.285
O42.9 Premature rupture of membranes, unspecified	0.715	0.285
T80.2 Infections following infusion, transfusion and therapeutic injection	0.714	0.286
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.714	0.286
O47.1 False labour at or after 37 completed weeks of gestation	0.713	0.287
S20-S29 Injuries to the thorax	0.712	0.288
M62 Other disorders of muscle	0.712	0.288
Y42.5 Other oestrogens and progestogens	0.712	0.288
Y52.3 Coronary vasodilators, not elsewhere classified	0.711	0.289
I00-I02 Acute rheumatic fever	0.711	0.289
I42 Cardiomyopathy	0.710	0.290
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.710	0.290
D37-D48 Neoplasms of uncertain or unknown behaviour	0.709	0.291
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.709	0.291
Y59 Other and unspecified vaccines and biological substances	0.708	0.292
Y58 Bacterial vaccines	0.708	0.292
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.708	0.292
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.708	0.292
Y50 Central nervous system stimulants, not elsewhere classified	0.708	0.292
Y48 Anaesthetics and therapeutic gases	0.708	0.292
Y47 Sedatives, hypnotics and antianxiety drugs	0.708	0.292
S08 Traumatic amputation of part of head	0.708	0.292
S07 Crushing injury of head	0.708	0.292
S04 Injury of cranial nerves	0.708	0.292
S03 Dislocation, sprain and strain of joints and ligaments of head	0.708	0.292
L60.2 Onychogryphosis	0.708	0.292
M89.9 Disorder of bone, unspecified	0.707	0.293
Y45.1 Salicylates	0.707	0.293
Y44 Agents primarily affecting blood constituents	0.705	0.295
O28 Abnormal findings on antenatal screening of mother	0.705	0.295
M70-M79 Other soft tissue disorders	0.705	0.295
C51-C58 Malignant neoplasms of female genital organs	0.704	0.296
S52.50 Fracture of lower end of radius (closed)	0.703	0.297
S80.1 Contusion of other and unspecified parts of lower leg	0.702	0.297
B18.1 Chronic viral hepatitis B without delta-agent	0.702	0.298
I51 Complications and ill-defined descriptions of heart disease	0.702	0.298
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.701	0.299
O33 Maternal care for known or suspected disproportion	0.700	0.300
O31 Complications specific to multiple gestation	0.700	0.300
T87 Complications peculiar to reattachment and amputation	0.700	0.300
S81.9 Open wound of lower leg, part unspecified	0.699	0.301
Q38-Q45 Other congenital malformations of the digestive system	0.699	0.301
T92 Sequelae of injuries of upper limb	0.698	0.302
C77.0 Lymph nodes of head, face and neck	0.698	0.302
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.697	0.303
L60.0 Ingrowing nail	0.697	0.303
Y95 Nosocomial condition	0.696	0.304
C34 Malignant neoplasm of bronchus and lung	0.696	0.304
I99 Other and unspecified disorders of circulatory system	0.695	0.305
T79 Certain early complications of trauma, not elsewhere classified	0.695	0.305
M43 Other deforming dorsopathies	0.694	0.306
S89 Other and unspecified injuries of lower leg	0.694	0.306
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.694	0.306
S09.8 Other specified injuries of head	0.693	0.307
S09.7 Multiple injuries of head	0.693	0.307
S09.2 Traumatic rupture of ear drum	0.693	0.307
S09.1 Injury of muscle and tendon of head	0.693	0.307
S09.0 Injury of blood vessels of head, not elsewhere classified	0.693	0.307
F80-F89 Disorders of psychological development	0.692	0.308
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.691	0.309
M15-M19 Arthrosis	0.691	0.309
Y84.2 Radiological procedure and radiotherapy	0.691	0.309
I52 Other heart disorders in diseases classified elsewhere	0.691	0.309
I48 Atrial fibrillation and flutter	0.691	0.309
I43 Cardiomyopathy in diseases classified elsewhere	0.691	0.309
I41 Myocarditis in diseases classified elsewhere	0.691	0.309
I40 Acute myocarditis	0.691	0.309
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.691	0.309
I32 Pericarditis in diseases classified elsewhere	0.691	0.309
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.690	0.310
O42.0 Premature rupture of membranes, onset of labour within 24 hours	0.688	0.312
S82.2 Fracture of shaft of tibia	0.687	0.313
S42.2 Fracture of upper end of humerus	0.686	0.314
T83.3 Mechanical complication of intra-uterine contraceptive device	0.686	0.314
D05 Carcinoma in situ of breast	0.685	0.315
I15 Secondary hypertension	0.685	0.315
I13 Hypertensive heart and renal disease	0.685	0.315
G24.5 Blepharospasm	0.684	0.316
S88 Traumatic amputation of lower leg	0.683	0.317
S87 Crushing injury of lower leg	0.683	0.317
S85 Injury of blood vessels at lower leg level	0.683	0.317
S84 Injury of nerves at lower leg level	0.683	0.317
M91-M94 Chondropathies	0.682	0.317
T15-T19 Effects of foreign body entering through natural orifice	0.682	0.318
C77.4 Inguinal and lower limb lymph nodes	0.681	0.319
Q00-Q07 Congenital malformations of the nervous system	0.681	0.319
E50-E64 Other nutritional deficiencies	0.681	0.319
O26.9 Pregnancy-related condition, unspecified	0.680	0.320
A30-A49 Other bacterial diseases	0.680	0.320
S86 Injury of muscle and tendon at lower leg level	0.679	0.321
W20-W49 Exposure to inanimate mechanical forces	0.679	0.321
M54.3 Sciatica	0.679	0.321
C25 Malignant neoplasm of pancreas	0.678	0.322
S80.8 Other superficial injuries of lower leg	0.678	0.322
C16 Malignant neoplasm of stomach	0.677	0.323
Y84.6 Urinary catheterisation	0.674	0.326
Q66 Congenital deformities of feet	0.674	0.326
G20 Parkinson's disease	0.673	0.327
B16 Acute hepatitis B	0.673	0.327
S78 Traumatic amputation of hip and thigh	0.672	0.328
S77 Crushing injury of hip and thigh	0.672	0.328
S76 Injury of muscle and tendon at hip and thigh level	0.672	0.328
S75 Injury of blood vessels at hip and thigh level	0.672	0.328
S74 Injury of nerves at hip and thigh level	0.672	0.328
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.672	0.328
I73 Other peripheral vascular diseases	0.672	0.328
M51 Other intervertebral disk disorders	0.672	0.328
O29 Complications of anaesthesia during pregnancy	0.672	0.328
O22 Venous complications in pregnancy	0.672	0.328
O25 Malnutrition in pregnancy	0.672	0.328
Y52.1 Calcium-channel blockers	0.672	0.328
S02.40 Fracture of malar and maxillary bones (closed)	0.671	0.329
C77.5 Intrapelvic lymph nodes	0.671	0.329
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.670	0.330
B19 Unspecified viral hepatitis	0.670	0.330
S40 Superficial injury of shoulder and upper arm	0.670	0.330
W18 Other fall on same level	0.670	0.330
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.670	0.330
F10 Mental and behavioural disorders due to use of alcohol	0.669	0.331
I11 Hypertensive heart disease	0.668	0.332
F99-F99 Unspecified mental disorder	0.668	0.332
I72 Other aneurysm	0.666	0.334
B85-B89 Pediculosis, acariasis and other infestations	0.666	0.334
B50-B64 Protozoal diseases	0.666	0.334
B20-B24 Human immunodeficiency virus [HIV] disease	0.666	0.334
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.666	0.334
A75-A79 Rickettsioses	0.666	0.334
A70-A74 Other diseases caused by chlamydiae	0.666	0.334
A65-A69 Other spirochaetal diseases	0.666	0.334
A20-A28 Certain zoonotic bacterial diseases	0.666	0.334
A15-A19 Tuberculosis	0.666	0.334
O36 Maternal care for other known or suspected foetal problems	0.666	0.334
Y57.9 Drug or medicament, unspecified	0.666	0.334
S98 Traumatic amputation of ankle and foot	0.665	0.335
S97 Crushing injury of ankle and foot	0.665	0.335
S96 Injury of muscle and tendon at ankle and foot level	0.665	0.335
S95 Injury of blood vessels at ankle and foot level	0.665	0.335
S94 Injury of nerves at ankle and foot level	0.665	0.335
G25.9 Extrapyramidal and movement disorder, unspecified	0.665	0.335
U51 Admission status on psychiatric patients	0.665	0.335
E10-E14 Diabetes mellitus	0.665	0.335
B99-B99 Other infectious diseases	0.664	0.336
C78.7 Secondary malignant neoplasm of liver	0.664	0.336
C17 Malignant neoplasm of small intestine	0.663	0.337
S82.00 Fracture of patella (closed)	0.662	0.338
C34.1 Upper lobe, bronchus or lung	0.662	0.338
V23 Motorcycle rider injured in collision with car, pick-up truck or van	0.662	0.338
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.661	0.339
Y41 Other systemic anti-infectives and antiparasitics	0.661	0.339
T88.8 Other specified complications of surgical and medical care, not elsewhere classified	0.660	0.340
C15 Malignant neoplasm of oesophagus	0.660	0.340
G91 Hydrocephalus	0.660	0.340
S82.31 Fracture of lower end of tibia (open)	0.660	0.340
W13 Fall from, out of or through building or structure	0.659	0.341
O44 Placenta praevia	0.658	0.342
G98 Other disorders of nervous system, not elsewhere classified	0.657	0.343
O99.5 Diseases of the respiratory system complicating pregnancy, childbirth and the puerperium	0.656	0.344
S82.50 Fracture of medial malleolus (closed)	0.656	0.344
G82 Paraplegia and tetraplegia	0.655	0.345
C18.4 Transverse colon	0.654	0.346
B90-B94 Sequelae of infectious and parasitic diseases	0.654	0.346
O41 Other disorders of amniotic fluid and membranes	0.654	0.346
S11 Open wound of neck	0.653	0.347
D05.9 Carcinoma in situ of breast, unspecified	0.653	0.347
S72.3 Fracture of shaft of femur	0.653	0.347
S02.9 Fracture of skull and facial bones, part unspecified	0.653	0.347
I30 Acute pericarditis	0.652	0.347
S48 Traumatic amputation of shoulder and upper arm	0.652	0.347
S45 Injury of blood vessels at shoulder and upper arm level	0.652	0.347
S44 Injury of nerves at shoulder and upper arm level	0.652	0.347
S47 Crushing injury of shoulder and upper arm	0.652	0.347
Y51 Drugs primarily affecting the autonomic nervous system	0.652	0.348
G23 Other degenerative diseases of basal ganglia	0.652	0.348
G21 Secondary Parkinsonism	0.652	0.348
G26 Extrapyramidal and movement disorders in diseases classified elsewhere	0.652	0.348
G22 Parkinsonism in diseases classified elsewhere	0.652	0.348
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified	0.652	0.348
O21.0 Mild hyperemesis gravidarum	0.651	0.349
M86 Osteomyelitis	0.651	0.349
B02 Zoster [herpes zoster]	0.650	0.350
C21 Malignant neoplasm of anus and anal canal	0.649	0.351
Q50-Q56 Congenital malformations of genital organs	0.649	0.351
S05.3 Ocular laceration without prolapse or loss of intraocular tissue	0.648	0.352
U80 Agent resistant to penicillin and related antibiotics	0.648	0.352
I31 Other diseases of pericardium	0.648	0.352
Y43 Primarily systemic agents	0.647	0.353
C40-C41 Malignant neoplasms of bone and articular cartilage	0.646	0.353
Y57.7 Vitamins, not elsewhere classified	0.645	0.354
Y57.6 Other diagnostic agents	0.645	0.354
Y57.4 Pharmaceutical excipients	0.645	0.354
Y57.3 Alcohol deterrents	0.645	0.354
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.645	0.354
Y57.1 Lipotropic drugs	0.645	0.354
Y57.0 Appetite depressants [anorectics]	0.645	0.354
C78.4 Secondary malignant neoplasm of small intestine	0.644	0.356
I74 Arterial embolism and thrombosis	0.644	0.356
M85 Other disorders of bone density and structure	0.644	0.356
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.643	0.357
S02.50 Fracture of tooth (closed)	0.642	0.358
S12 Fracture of neck	0.642	0.358
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract	0.642	0.358
M62.8 Other specified disorders of muscle	0.642	0.358
M89.97 Disorder of bone, unspecified (Ankle and foot)	0.641	0.359
Y84.1 Kidney dialysis	0.641	0.359
B25-B34 Other viral diseases	0.640	0.360
G36 Other acute disseminated demyelination	0.640	0.360
I71 Aortic aneurysm and dissection	0.640	0.360
S00.2 Other superficial injuries of eyelid and periocular area	0.639	0.361
T83.1 Mechanical complication of other urinary devices and implants	0.639	0.361
S81.8 Open wound of other parts of lower leg	0.639	0.361
C76 Malignant neoplasm of other and ill-defined sites	0.639	0.361
M19 Other arthrosis	0.639	0.361
S59 Other and unspecified injuries of forearm	0.638	0.362
S58 Traumatic amputation of forearm	0.638	0.362
S57 Crushing injury of forearm	0.638	0.362
S56 Injury of muscle and tendon at forearm level	0.638	0.362
S55 Injury of blood vessels at forearm level	0.638	0.362
S54 Injury of nerves at forearm level	0.638	0.362
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.638	0.362
M53 Other dorsopathies, not elsewhere classified	0.638	0.362
G31.9 Degenerative disease of nervous system, unspecified	0.638	0.362
B35-B49 Mycoses	0.637	0.363
C77.1 Intrathoracic lymph nodes	0.637	0.363
B17 Other acute viral hepatitis	0.637	0.363
L65 Other nonscarring hair loss	0.636	0.363
M90 Osteopathies in diseases classified elsewhere	0.636	0.364
U88 Agent resistant to multiple antibiotics	0.636	0.364
I37.1 Pulmonary valve insufficiency	0.636	0.364
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium	0.635	0.364
O97 Death from sequelae of direct obstetric causes	0.635	0.364
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery	0.635	0.364
O95 Obstetric death of unspecified cause	0.635	0.364
O94 Sequelae of complication of pregnancy, childbirth and the puerperium	0.635	0.364
M05-M14 Inflammatory polyarthropathies	0.635	0.365
S02.7 Multiple fractures involving skull and facial bones	0.635	0.365
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.634	0.366
S79 Other and unspecified injuries of hip and thigh	0.633	0.367
G09 Sequelae of inflammatory diseases of central nervous system	0.632	0.368
B15 Acute hepatitis A	0.631	0.369
O42.2 Premature rupture of membranes, labour delayed by therapy	0.631	0.369
C18.3 Hepatic flexure	0.631	0.369
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.631	0.369
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.631	0.369
O99.4 Diseases of the circulatory system complicating pregnancy, childbirth and the puerperium	0.631	0.369
I51.8 Other ill-defined heart diseases	0.630	0.370
M54.6 Pain in thoracic spine	0.629	0.371
O32 Maternal care for known or suspected malpresentation of foetus	0.629	0.371
I98 Other disorders of circulatory system in diseases classified elsewhere	0.629	0.371
G70-G73 Diseases of myoneural junction and muscle	0.629	0.371
S42.20 Fracture of upper end of humerus (closed)	0.629	0.371
B65-B83 Helminthiases	0.628	0.371
G90.9 Disorder of autonomic nervous system, unspecified	0.628	0.372
S71.1 Open wound of thigh	0.628	0.372
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.628	0.372
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.627	0.373
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.626	0.374
Q35-Q37 Cleft lip and cleft palate	0.626	0.374
Q30-Q34 Congenital malformations of the respiratory system	0.626	0.374
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.626	0.374
S46.0 Injury of tendon of the rotator cuff of shoulder	0.625	0.375
Y49.5 Other antipsychotics and neuroleptics	0.625	0.375
M40 Kyphosis and lordosis	0.625	0.375
G80 Infantile cerebral palsy	0.625	0.375
S92.0 Fracture of calcaneus	0.625	0.375
T83.0 Mechanical complication of urinary (indwelling) catheter	0.625	0.375
G06 Intracranial and intraspinal abscess and granuloma	0.624	0.376
O43.8 Other placental disorders	0.623	0.377
S49 Other and unspecified injuries of shoulder and upper arm	0.623	0.377
C97 Malignant neoplasms of independent (primary) multiple sites	0.622	0.378
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system	0.621	0.379
Y52.8 Antivaricose drugs, including sclerosing agents	0.621	0.379
Y52.7 Peripheral vasodilators	0.621	0.379
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs	0.621	0.379
Y52.0 Cardiac-stimulant glycosides and drugs of similar action	0.621	0.379
Y42.7 Androgens and anabolic congeners	0.620	0.380
O24.0 Pre-existing diabetes mellitus, insulin-dependent	0.620	0.380
M79 Other soft tissue disorders, not elsewhere classified	0.620	0.380
X40-X49 Accidental poisoning by and exposure to noxious substances	0.620	0.380
M19.9 Arthrosis, unspecified	0.620	0.380
S41.0 Open wound of shoulder	0.619	0.381
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.619	0.381
S82.1 Fracture of upper end of tibia	0.619	0.381
L73.8 Other specified follicular disorders	0.619	0.381
E55 Vitamin D deficiency	0.619	0.381
I77 Other disorders of arteries and arterioles	0.619	0.381
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.618	0.382
S51.0 Open wound of elbow	0.618	0.382
T86.8 Failure and rejection of other transplanted organs and tissues	0.618	0.382
S50 Superficial injury of forearm	0.617	0.383
I27.8 Other specified pulmonary heart diseases	0.617	0.383
I27.1 Kyphoscoliotic heart disease	0.617	0.383
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.617	0.383
M87 Osteonecrosis	0.617	0.383

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations