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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117654141
log Bayes Factor = 19.1486
Chromosome 15   position 38,120,376  (GRCh37) Explore rs117654141 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
M20-M25 Other joint disorders
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
R07 Pain in throat and chest
0.990 0.010 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.985 0.015 0.000
M23 Internal derangement of knee
0.984 0.016 0.000
I20 Angina pectoris
0.982 0.018 0.000
Z80 Family history of malignant neoplasm
0.982 0.018 0.000
Chapter V Mental and behavioural disorders
0.980 0.020 0.000
R07.4 Chest pain, unspecified
0.979 0.021 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.978 0.022 0.000
I25 Chronic ischaemic heart disease
0.978 0.022 0.000
E70-E90 Metabolic disorders
0.976 0.024 0.000
I60-I69 Cerebrovascular diseases
0.976 0.024 0.000
F30-F39 Mood [affective] disorders
0.971 0.029 0.000
M23.3 Other meniscus derangements
0.968 0.032 0.000
I20.0 Unstable angina
0.963 0.037 0.000
F32 Depressive episode
0.961 0.039 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.960 0.040 0.000
I47 Paroxysmal tachycardia
0.955 0.045 0.000
E10-E14 Diabetes mellitus
0.954 0.046 0.000
F32.9 Depressive episode, unspecified
0.953 0.047 0.000
Z80.0 Family history of malignant neoplasm of digestive organs
0.953 0.047 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.952 0.048 0.000
M25 Other joint disorders, not elsewhere classified
0.936 0.064 0.000
M35 Other systemic involvement of connective tissue
0.935 0.065 0.000
M23.30 Other meniscus derangements (Multiple sites)
0.931 0.069 0.000
R50-R69 General symptoms and signs
0.928 0.072 0.000
I45 Other conduction disorders
0.927 0.073 0.000
M45-M49 Spondylopathies
0.926 0.074 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.925 0.075 0.000
S00-S09 Injuries to the head
0.924 0.076 0.000
S60-S69 Injuries to the wrist and hand
0.921 0.079 0.000
I51 Complications and ill-defined descriptions of heart disease
0.920 0.080 0.000
I74 Arterial embolism and thrombosis
0.917 0.083 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.912 0.088 0.000
M20 Acquired deformities of fingers and toes
0.907 0.093 0.000
R05 Cough
0.906 0.094 0.000
Chapter XX External causes of morbidity and mortality
0.900 0.100 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.900 0.100 0.000
M23.36 Other meniscus derangements (Other and unspecified lateral meniscus)
0.896 0.104 0.000
M35.3 Polymyalgia rheumatica
0.889 0.111 0.000
R01 Cardiac murmurs and other cardiac sounds
0.887 0.113 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.886 0.114 0.000
Z98 Other postsurgical states
0.885 0.115 0.000
E11 Non-insulin-dependent diabetes mellitus
0.883 0.117 0.000
R47-R49 Symptoms and signs involving speech and voice
0.880 0.120 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.880 0.120 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.879 0.121 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.879 0.121 0.000
I45.1 Other and unspecified right bundle-branch block
0.876 0.124 0.000
R00 Abnormalities of heart beat
0.873 0.127 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.872 0.128 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.872 0.128 0.000
I73 Other peripheral vascular diseases
0.872 0.128 0.000
I20.9 Angina pectoris, unspecified
0.871 0.129 0.000
E00-E07 Disorders of thyroid gland
0.870 0.130 0.000
E87.2 Acidosis
0.869 0.131 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.868 0.132 0.000
I47.2 Ventricular tachycardia
0.867 0.133 0.000
M70-M79 Other soft tissue disorders
0.864 0.136 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.862 0.138 0.000
I47.1 Supraventricular tachycardia
0.862 0.138 0.000
E83 Disorders of mineral metabolism
0.858 0.142 0.000
M25.7 Osteophyte
0.858 0.142 0.000
I77 Other disorders of arteries and arterioles
0.857 0.143 0.000
I74.3 Embolism and thrombosis of arteries of the lower extremities
0.856 0.144 0.000
R07.2 Precordial pain
0.852 0.148 0.000
M40-M43 Deforming dorsopathies
0.852 0.148 0.000
R06 Abnormalities of breathing
0.851 0.149 0.000
M15-M19 Arthrosis
0.850 0.150 0.000
Z80.3 Family history of malignant neoplasm of breast
0.849 0.151 0.000
S90-S99 Injuries to the ankle and foot
0.848 0.152 0.000
Z86 Personal history of certain other diseases
0.841 0.159 0.000
S62 Fracture at wrist and hand level
0.840 0.160 0.000
I51.7 Cardiomegaly
0.835 0.165 0.000
I67 Other cerebrovascular diseases
0.831 0.169 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.831 0.169 0.000
Z86.4 Personal history of psychoactive substance abuse
0.830 0.170 0.000
Chapter VI Diseases of the nervous system
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
M50-M54 Other dorsopathies
0.828 0.172 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.826 0.174 0.000
M20.5 Other deformities of toe(s) (acquired)
0.826 0.174 0.000
M23.5 Chronic instability of knee
0.822 0.178 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.819 0.181 0.000
I05-I09 Chronic rheumatic heart diseases
0.818 0.182 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.818 0.182 0.000
M47 Spondylosis
0.815 0.185 0.000
S20-S29 Injuries to the thorax
0.814 0.186 0.000
R51 Headache
0.813 0.187 0.000
M65-M68 Disorders of synovium and tendon
0.812 0.188 0.000
I49 Other cardiac arrhythmias
0.811 0.189 0.000
I50 Heart failure
0.811 0.189 0.000
R47 Speech disturbances, not elsewhere classified
0.808 0.192 0.000
R01.1 Cardiac murmur, unspecified
0.808 0.192 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.806 0.194 0.000
E10 Insulin-dependent diabetes mellitus
0.805 0.195 0.000
R53 Malaise and fatigue
0.803 0.197 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.803 0.197 0.000
I69 Sequelae of cerebrovascular disease
0.802 0.198 0.000
M25.5 Pain in joint
0.801 0.199 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.801 0.199 0.000
E11.9 Without complications
0.798 0.202 0.000
I65.2 Occlusion and stenosis of carotid artery
0.798 0.202 0.000
Chapter VIII Diseases of the ear and mastoid process
0.798 0.202 0.000
Z83 Family history of other specific disorders
0.796 0.203 0.000
Chapter X Diseases of the respiratory system
0.796 0.204 0.000
E87.5 Hyperkalaemia
0.796 0.204 0.000
I73.9 Peripheral vascular disease, unspecified
0.794 0.206 0.000
S00 Superficial injury of head
0.789 0.211 0.000
Chapter XIV Diseases of the genitourinary system
0.789 0.211 0.000
I60 Subarachnoid haemorrhage
0.789 0.211 0.000
Z95.1 Presence of aortocoronary bypass graft
0.787 0.213 0.000
I25.1 Atherosclerotic heart disease
0.786 0.214 0.000
I31 Other diseases of pericardium
0.786 0.214 0.000
R63 Symptoms and signs concerning food and fluid intake
0.785 0.215 0.000
M22 Disorders of patella
0.781 0.219 0.000
M75 Shoulder lesions
0.779 0.221 0.000
S50-S59 Injuries to the elbow and forearm
0.777 0.223 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.777 0.223 0.000
E83.5 Disorders of calcium metabolism
0.777 0.223 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.775 0.225 0.000
R60 Oedema, not elsewhere classified
0.775 0.225 0.000
S62.6 Fracture of other finger
0.774 0.226 0.000
I46 Cardiac arrest
0.773 0.227 0.000
M25.74 Osteophyte (Hand)
0.772 0.228 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.771 0.229 0.000
M19 Other arthrosis
0.770 0.230 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.770 0.230 0.000
M48 Other spondylopathies
0.769 0.231 0.000
F31 Bipolar affective disorder
0.769 0.231 0.000
Z90.2 Acquired absence of lung [part of]
0.769 0.231 0.000
R00.2 Palpitations
0.768 0.232 0.000
S01 Open wound of head
0.767 0.233 0.000
I25.5 Ischaemic cardiomyopathy
0.767 0.233 0.000
I77.1 Stricture of artery
0.766 0.234 0.000
I25.2 Old myocardial infarction
0.764 0.236 0.000
M91-M94 Chondropathies
0.762 0.238 0.000
I24 Other acute ischaemic heart diseases
0.761 0.239 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.759 0.241 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.758 0.242 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.758 0.242 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.757 0.243 0.000
S09 Other and unspecified injuries of head
0.756 0.244 0.000
M80-M85 Disorders of bone density and structure
0.755 0.245 0.000
R00.0 Tachycardia, unspecified
0.754 0.246 0.000
Z80.8 Family history of malignant neoplasm of other organs or systems
0.751 0.249 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.750 0.250 0.000
M23.8 Other internal derangements of knee
0.748 0.251 0.000
T66-T78 Other and unspecified effects of external causes
0.748 0.252 0.000
E20-E35 Disorders of other endocrine glands
0.747 0.253 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.747 0.253 0.000
M43 Other deforming dorsopathies
0.746 0.254 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.746 0.254 0.000
I71 Aortic aneurysm and dissection
0.745 0.255 0.000
Z82.3 Family history of stroke
0.744 0.256 0.000
Z80.5 Family history of malignant neoplasm of urinary tract
0.743 0.257 0.000
N30-N39 Other diseases of urinary system
0.743 0.257 0.000
M47.9 Spondylosis, unspecified
0.742 0.258 0.000
E87.7 Fluid overload
0.741 0.259 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.739 0.261 0.000
M31 Other necrotising vasculopathies
0.738 0.262 0.000
F33 Recurrent depressive disorder
0.738 0.262 0.000
E14 Unspecified diabetes mellitus
0.737 0.263 0.000
R55 Syncope and collapse
0.737 0.263 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.733 0.267 0.000
R06.4 Hyperventilation
0.732 0.268 0.000
S80-S89 Injuries to the knee and lower leg
0.732 0.268 0.000
M54 Dorsalgia
0.732 0.268 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.731 0.268 0.000
W00-W19 Falls
0.731 0.269 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.731 0.269 0.000
M23.4 Loose body in knee
0.730 0.270 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.730 0.270 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.730 0.270 0.000
Z98.0 Intestinal bypass and anastomosis status
0.728 0.272 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.727 0.273 0.000
R07.3 Other chest pain
0.727 0.273 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.725 0.275 0.000
I62 Other nontraumatic intracranial haemorrhage
0.725 0.275 0.000
E87.6 Hypokalaemia
0.725 0.275 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.725 0.275 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.724 0.276 0.000
I51.8 Other ill-defined heart diseases
0.722 0.278 0.000
I63 Cerebral infarction
0.721 0.279 0.000
M19.9 Arthrosis, unspecified
0.721 0.279 0.000
I22 Subsequent myocardial infarction
0.721 0.279 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.721 0.279 0.000
R42 Dizziness and giddiness
0.720 0.280 0.000
R57 Shock, not elsewhere classified
0.719 0.281 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
R54 Senility
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.717 0.283 0.000
M34 Systemic sclerosis
0.717 0.283 0.000
M33 Dermatopolymyositis
0.717 0.283 0.000
M32 Systemic lupus erythematosus
0.717 0.283 0.000
M30 Polyarteritis nodosa and related conditions
0.717 0.283 0.000
M21 Other acquired deformities of limbs
0.717 0.283 0.000
N32 Other disorders of bladder
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
Z89 Acquired absence of limb
0.716 0.284 0.000
Z84 Family history of other conditions
0.716 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.284 0.000
I48 Atrial fibrillation and flutter
0.715 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.284 0.000
I40 Acute myocarditis
0.715 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.284 0.000
I37 Pulmonary valve disorders
0.715 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.284 0.000
I33 Acute and subacute endocarditis
0.715 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.284 0.000
I30 Acute pericarditis
0.715 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.284 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.715 0.284 0.000
E40-E46 Malnutrition
0.715 0.285 0.000
I35 Nonrheumatic aortic valve disorders
0.714 0.286 0.000
E05.9 Thyrotoxicosis, unspecified
0.713 0.287 0.000
R40 Somnolence, stupor and coma
0.712 0.288 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.712 0.288 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.711 0.289 0.000
R56 Convulsions, not elsewhere classified
0.711 0.289 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.711 0.289 0.000
M86-M90 Other osteopathies
0.711 0.289 0.000
Z97 Presence of other devices
0.710 0.290 0.000
R07.1 Chest pain on breathing
0.710 0.290 0.000
S69 Other and unspecified injuries of wrist and hand
0.709 0.291 0.000
Z92 Personal history of medical treatment
0.709 0.291 0.000
M24 Other specific joint derangements
0.709 0.291 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.708 0.292 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.708 0.292 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.708 0.292 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.708 0.292 0.000
Z82.2 Family history of deafness and hearing loss
0.708 0.292 0.000
Z82.1 Family history of blindness and visual loss
0.708 0.292 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.708 0.292 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.708 0.292 0.000
I74.5 Embolism and thrombosis of iliac artery
0.707 0.293 0.000
R06.0 Dyspnoea
0.707 0.293 0.000
I78 Diseases of capillaries
0.707 0.293 0.000
S67 Crushing injury of wrist and hand
0.707 0.293 0.000
I95 Hypotension
0.706 0.294 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.706 0.294 0.000
I72 Other aneurysm
0.706 0.294 0.000
I70 Atherosclerosis
0.706 0.294 0.000
M23.51 Chronic instability of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.706 0.294 0.000
M23.9 Internal derangement of knee, unspecified
0.705 0.295 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.705 0.295 0.000
M23.1 Discoid meniscus (congenital)
0.705 0.295 0.000
M23.0 Cystic meniscus
0.705 0.295 0.000
I20.1 Angina pectoris with documented spasm
0.704 0.296 0.000
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues
0.704 0.296 0.000
Z80.6 Family history of leukaemia
0.704 0.296 0.000
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs
0.704 0.296 0.000
Z98.1 Arthrodesis status
0.704 0.296 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.704 0.296 0.000
R47.0 Dysphasia and aphasia
0.703 0.297 0.000
F99-F99 Unspecified mental disorder
0.703 0.297 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.703 0.297 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
F70-F79 Mental retardation
0.703 0.297 0.000
F60-F69 Disorders of adult personality and behaviour
0.703 0.297 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.703 0.297 0.000
M25.77 Osteophyte (Ankle and foot)
0.703 0.297 0.000
M45 Ankylosing spondylitis
0.702 0.298 0.000
S90 Superficial injury of ankle and foot
0.702 0.298 0.000
I25.6 Silent myocardial ischaemia
0.701 0.299 0.000
I25.4 Coronary artery aneurysm
0.701 0.299 0.000
I25.3 Aneurysm of heart
0.701 0.299 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.701 0.299 0.000
S70-S79 Injuries to the hip and thigh
0.701 0.299 0.000
E88 Other metabolic disorders
0.700 0.300 0.000
E85 Amyloidosis
0.700 0.300 0.000
E84 Cystic fibrosis
0.700 0.300 0.000
E79 Disorders of purine and pyrimidine metabolism
0.700 0.300 0.000
E77 Disorders of glycoprotein metabolism
0.700 0.300 0.000
E76 Disorders of glycosaminoglycan metabolism
0.700 0.300 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.700 0.300 0.000
E74 Other disorders of carbohydrate metabolism
0.700 0.300 0.000
E73 Lactose intolerance
0.700 0.300 0.000
E72 Other disorders of amino-acid metabolism
0.700 0.300 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.700 0.300 0.000
E70 Disorders of aromatic amino-acid metabolism
0.700 0.300 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.700 0.300 0.000
S62.60 Fracture of other finger (closed)
0.700 0.300 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.700 0.300 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.700 0.300 0.000
I61 Intracerebral haemorrhage
0.700 0.300 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.697 0.303 0.000
M20.2 Hallux rigidus
0.697 0.303 0.000
F38 Other mood [affective] disorders
0.696 0.304 0.000
F34 Persistent mood [affective] disorders
0.696 0.304 0.000
F30 Manic episode
0.696 0.304 0.000
F39 Unspecified mood [affective] disorder
0.696 0.304 0.000
I50.9 Heart failure, unspecified
0.696 0.304 0.000
E11.2 With renal complications
0.695 0.304 0.000
I38 Endocarditis, valve unspecified
0.695 0.305 0.000
I10-I15 Hypertensive diseases
0.695 0.305 0.000
M75.4 Impingement syndrome of shoulder
0.694 0.306 0.000
R63.4 Abnormal weight loss
0.694 0.306 0.000
M23.39 Other meniscus derangements (Unspecified ligament or Unspecified meniscus)
0.694 0.306 0.000
M23.37 Other meniscus derangements-Capsular lig
0.694 0.306 0.000
M23.35 Other meniscus derangements (Posterior horn of lateral meniscus)
0.694 0.306 0.000
M23.34 Other meniscus derangements (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.694 0.306 0.000
M23.31 Other meniscus derangements (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.694 0.306 0.000
I51.9 Heart disease, unspecified
0.693 0.307 0.000
R45 Symptoms and signs involving emotional state
0.693 0.307 0.000
M20.3 Other deformity of hallux (acquired)
0.693 0.307 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.692 0.308 0.000
E04 Other non-toxic goitre
0.691 0.309 0.000
V10-V19 Pedal cyclist injured in transport accident
0.690 0.310 0.000
M18 Arthrosis of first carpometacarpal joint
0.690 0.310 0.000
I67.8 Other specified cerebrovascular diseases
0.689 0.310 0.000
F32.8 Other depressive episodes
0.689 0.311 0.000
F32.1 Moderate depressive episode
0.689 0.311 0.000
F32.0 Mild depressive episode
0.689 0.311 0.000
X60-X84 Intentional self-harm
0.689 0.311 0.000
R60.0 Localised oedema
0.689 0.311 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.689 0.311 0.000
E87.4 Mixed disorder of acid-base balance
0.689 0.311 0.000
E87.3 Alkalosis
0.689 0.311 0.000
E87.0 Hyperosmolality and hypernatraemia
0.689 0.311 0.000
E06 Thyroiditis
0.686 0.313 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.686 0.314 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.685 0.315 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.685 0.315 0.000
I47.0 Reentry ventricular arrhythmia
0.685 0.315 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.685 0.315 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.685 0.315 0.000
E13 Other specified diabetes mellitus
0.684 0.316 0.000
E12 Malnutrition-related diabetes mellitus
0.684 0.316 0.000
M77 Other enthesopathies
0.683 0.317 0.000
W20-W49 Exposure to inanimate mechanical forces
0.683 0.317 0.000
Z94 Transplanted organ and tissue status
0.683 0.317 0.000
S40-S49 Injuries to the shoulder and upper arm
0.683 0.317 0.000
Z95.3 Presence of xenogenic heart valve
0.682 0.317 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.682 0.318 0.000
Z83.7 Family history of diseases of the digestive system
0.682 0.318 0.000
R06.2 Wheezing
0.681 0.319 0.000
E11.3 With ophthalmic complications
0.681 0.319 0.000
R47.8 Other and unspecified speech disturbances
0.680 0.320 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.680 0.320 0.000
I31.9 Disease of pericardium, unspecified
0.680 0.320 0.000
Z90.1 Acquired absence of breast(s)
0.680 0.320 0.000
Z98.2 Presence of cerebrospinal fluid drainage device
0.680 0.320 0.000
Z95.0 Presence of cardiac pacemaker
0.678 0.322 0.000
M46 Other inflammatory spondylopathies
0.676 0.324 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.675 0.325 0.000
I69.3 Sequelae of cerebral infarction
0.675 0.325 0.000
N32.9 Bladder disorder, unspecified
0.673 0.327 0.000
Chapter I Certain infectious and parasitic diseases
0.672 0.328 0.000
M25.9 Joint disorder, unspecified
0.671 0.329 0.000
M25.8 Other specified joint disorders
0.671 0.329 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.671 0.329 0.000
M25.3 Other instability of joint
0.671 0.329 0.000
M25.2 Flail joint
0.671 0.329 0.000
M25.1 Fistula of joint
0.671 0.329 0.000
M25.0 Haemarthrosis
0.671 0.329 0.000
R07.0 Pain in throat
0.670 0.329 0.000
M35.9 Systemic involvement of connective tissue, unspecified
0.670 0.329 0.000
M35.8 Other specified systemic involvement of connective tissue
0.670 0.329 0.000
M35.7 Hypermobility syndrome
0.670 0.329 0.000
M35.6 Relapsing panniculitis [Weber-Christian]
0.670 0.329 0.000
M35.5 Multifocal fibrosclerosis
0.670 0.329 0.000
M35.4 Diffuse (eosinophilic) fasciitis
0.670 0.329 0.000
M35.2 Behcet's disease
0.670 0.329 0.000
M35.1 Other overlap syndromes
0.670 0.329 0.000
M35.0 Sicca syndrome [Sjogren]
0.670 0.329 0.000
M43.1 Spondylolisthesis
0.670 0.330 0.000
I49.4 Other and unspecified premature depolarisation
0.669 0.331 0.000
J95-J99 Other diseases of the respiratory system
0.668 0.332 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.667 0.333 0.000
Z98.8 Other specified postsurgical states
0.667 0.333 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.667 0.333 0.000
M17 Gonarthrosis [arthrosis of knee]
0.667 0.333 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.666 0.334 0.000
I44 Atrioventricular and left bundle-branch block
0.666 0.334 0.000
T18 Foreign body in alimentary tract
0.666 0.334 0.000
R68 Other general symptoms and signs
0.666 0.334 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.666 0.334 0.000
R62 Lack of expected normal physiological development
0.666 0.334 0.000
R64 Cachexia
0.666 0.334 0.000
R58 Haemorrhage, not elsewhere classified
0.666 0.334 0.000
G90-G99 Other disorders of the nervous system
0.665 0.335 0.000
I45.9 Conduction disorder, unspecified
0.664 0.336 0.000
I45.8 Other specified conduction disorders
0.664 0.336 0.000
I45.6 Preexcitation syndrome
0.664 0.336 0.000
I45.5 Other specified heart block
0.664 0.336 0.000
I45.4 Nonspecific intraventricular block
0.664 0.336 0.000
I45.3 Trifascicular block
0.664 0.336 0.000
I45.2 Bifascicular block
0.664 0.336 0.000
I45.0 Right fascicular block
0.664 0.336 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.664 0.336 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.664 0.336 0.000
M49 Spondylopathies in diseases classified elsewhere
0.664 0.336 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.664 0.336 0.000
H90-H95 Other disorders of ear
0.664 0.336 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.663 0.337 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.663 0.337 0.000
M25.51 Pain in joint (Shoulder region)
0.663 0.337 0.000
S08 Traumatic amputation of part of head
0.662 0.338 0.000
S07 Crushing injury of head
0.662 0.338 0.000
S06 Intracranial injury
0.662 0.338 0.000
S05 Injury of eye and orbit
0.662 0.338 0.000
S04 Injury of cranial nerves
0.662 0.338 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.662 0.338 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.662 0.338 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.662 0.338 0.000
S68 Traumatic amputation of wrist and hand
0.661 0.339 0.000
S65 Injury of blood vessels at wrist and hand level
0.661 0.339 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.661 0.339 0.000
S60 Superficial injury of wrist and hand
0.661 0.339 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.660 0.340 0.000
I42 Cardiomyopathy
0.660 0.340 0.000
I34 Nonrheumatic mitral valve disorders
0.659 0.341 0.000
I51.6 Cardiovascular disease, unspecified
0.659 0.341 0.000
I51.5 Myocardial degeneration
0.659 0.341 0.000
I51.4 Myocarditis, unspecified
0.659 0.341 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.659 0.341 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.659 0.341 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.659 0.341 0.000
I51.0 Cardiac septal defect, acquired
0.659 0.341 0.000
I67.9 Cerebrovascular disease, unspecified
0.659 0.341 0.000
M48.0 Spinal stenosis
0.657 0.343 0.000
I74.9 Embolism and thrombosis of unspecified artery
0.657 0.343 0.000
I74.8 Embolism and thrombosis of other arteries
0.657 0.343 0.000
I74.4 Embolism and thrombosis of arteries of extremities, unspecified
0.657 0.343 0.000
I74.2 Embolism and thrombosis of arteries of the upper extremities
0.657 0.343 0.000
I74.1 Embolism and thrombosis of other and unspecified parts of aorta
0.657 0.343 0.000
I74.0 Embolism and thrombosis of abdominal aorta
0.657 0.343 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.657 0.343 0.000
M25.50 Pain in joint (Multiple sites)
0.656 0.343 0.000
R52 Pain, not elsewhere classified
0.656 0.344 0.000
I08 Multiple valve diseases
0.656 0.344 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.655 0.345 0.000
E10.9 Without complications
0.655 0.345 0.000
Z90.8 Acquired absence of other organs
0.653 0.346 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.653 0.346 0.000
Z90.0 Acquired absence of part of head and neck
0.653 0.346 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.652 0.348 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.651 0.349 0.000
E11.4 With neurological complications
0.651 0.349 0.000
S02 Fracture of skull and facial bones
0.651 0.349 0.000
E50-E64 Other nutritional deficiencies
0.651 0.349 0.000
M20.0 Deformity of finger(s)
0.651 0.349 0.000
S64 Injury of nerves at wrist and hand level
0.650 0.350 0.000
S91 Open wound of ankle and foot
0.648 0.351 0.000
M75.1 Rotator cuff syndrome
0.648 0.352 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.648 0.352 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.648 0.352 0.000
N32.8 Other specified disorders of bladder
0.648 0.352 0.000
M67 Other disorders of synovium and tendon
0.647 0.352 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.646 0.354 0.000
Y35-Y36 Legal intervention and operations of war
0.646 0.354 0.000
Y10-Y34 Event of undetermined intent
0.646 0.354 0.000
Y00-Y09 Assault
0.646 0.354 0.000
X85-X99 Assault
0.646 0.354 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.646 0.354 0.000
X50-X57 Overexertion, travel and privation
0.646 0.354 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.646 0.354 0.000
X30-X39 Exposure to forces of nature
0.646 0.354 0.000
X20-X29 Contact with venomous animals and plants
0.646 0.354 0.000
X10-X19 Contact with heat and hot substances
0.646 0.354 0.000
X00-X09 Exposure to smoke, fire and flames
0.646 0.354 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.646 0.354 0.000
W75-W84 Other accidental threats to breathing
0.646 0.354 0.000
W65-W74 Accidental drowning and submersion
0.646 0.354 0.000
W50-W64 Exposure to animate mechanical forces
0.646 0.354 0.000
V98-V99 Other and unspecified transport accidents
0.646 0.354 0.000
V95-V97 Air and space transport accidents
0.646 0.354 0.000
V90-V94 Water transport accidents
0.646 0.354 0.000
V80-V89 Other land transport accidents
0.646 0.354 0.000
V70-V79 Bus occupant injured in transport accident
0.646 0.354 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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