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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117676517
log Bayes Factor = 13.7989
Chromosome 11   position 43,925,152  (GRCh37) Explore rs117676517 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
0.999 0.001 0.000
N30-N39 Other diseases of urinary system
0.998 0.002 0.000
M70-M79 Other soft tissue disorders
0.997 0.003 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.994 0.006 0.000
N60-N64 Disorders of breast
0.986 0.014 0.000
Chapter VI Diseases of the nervous system
0.986 0.014 0.000
M79.6 Pain in limb
0.981 0.019 0.000
N30 Cystitis
0.978 0.022 0.000
M20-M25 Other joint disorders
0.977 0.023 0.000
I31 Other diseases of pericardium
0.971 0.029 0.000
Chapter I Certain infectious and parasitic diseases
0.967 0.033 0.000
I50 Heart failure
0.967 0.033 0.000
E65-E68 Obesity and other hyperalimentation
0.965 0.035 0.000
G40-G47 Episodic and paroxysmal disorders
0.965 0.035 0.000
M79.66 Pain in limb (Lower leg)
0.964 0.036 0.000
M20 Acquired deformities of fingers and toes
0.949 0.051 0.000
I05-I09 Chronic rheumatic heart diseases
0.948 0.052 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.946 0.054 0.000
E66 Obesity
0.944 0.056 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.935 0.065 0.000
M79.8 Other specified soft tissue disorders
0.933 0.067 0.000
N30.9 Cystitis, unspecified
0.932 0.068 0.000
M79.0 Rheumatism, unspecified
0.932 0.068 0.000
N32 Other disorders of bladder
0.928 0.072 0.000
I31.3 Pericardial effusion (noninflammatory)
0.927 0.073 0.000
N39 Other disorders of urinary system
0.926 0.074 0.000
M15-M19 Arthrosis
0.926 0.074 0.000
E66.9 Obesity, unspecified
0.925 0.075 0.000
N63 Unspecified lump in breast
0.918 0.082 0.000
M20.4 Other hammer toe(s) (acquired)
0.918 0.082 0.000
I44 Atrioventricular and left bundle-branch block
0.915 0.085 0.000
Chapter V Mental and behavioural disorders
0.910 0.090 0.000
G40 Epilepsy
0.909 0.091 0.000
N60 Benign mammary dysplasia
0.904 0.096 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.902 0.098 0.000
Chapter XX External causes of morbidity and mortality
0.896 0.104 0.000
I50.9 Heart failure, unspecified
0.895 0.105 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.893 0.107 0.000
I35 Nonrheumatic aortic valve disorders
0.892 0.108 0.000
I50.0 Congestive heart failure
0.890 0.110 0.000
A30-A49 Other bacterial diseases
0.887 0.113 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.887 0.113 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.885 0.115 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.883 0.117 0.000
B95-B98 Bacterial, viral and other infectious agents
0.881 0.119 0.000
I71 Aortic aneurysm and dissection
0.881 0.119 0.000
N61 Inflammatory disorders of breast
0.881 0.119 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.876 0.124 0.000
M45-M49 Spondylopathies
0.875 0.125 0.000
I51 Complications and ill-defined descriptions of heart disease
0.872 0.128 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.871 0.129 0.000
Chapter X Diseases of the respiratory system
0.871 0.129 0.000
S80-S89 Injuries to the knee and lower leg
0.869 0.131 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.866 0.134 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.863 0.137 0.000
F30-F39 Mood [affective] disorders
0.860 0.140 0.000
M35 Other systemic involvement of connective tissue
0.858 0.142 0.000
G40.9 Epilepsy, unspecified
0.857 0.143 0.000
I08 Multiple valve diseases
0.854 0.146 0.000
S20-S29 Injuries to the thorax
0.854 0.146 0.000
M17 Gonarthrosis [arthrosis of knee]
0.851 0.149 0.000
E80.4 Gilbert's syndrome
0.848 0.152 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.846 0.154 0.000
I31.9 Disease of pericardium, unspecified
0.845 0.155 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.845 0.155 0.000
N32.8 Other specified disorders of bladder
0.843 0.157 0.000
I07 Rheumatic tricuspid valve diseases
0.842 0.158 0.000
D69 Purpura and other haemorrhagic conditions
0.839 0.161 0.000
I49 Other cardiac arrhythmias
0.839 0.161 0.000
R42 Dizziness and giddiness
0.838 0.162 0.000
M16 Coxarthrosis [arthrosis of hip]
0.834 0.166 0.000
R40 Somnolence, stupor and coma
0.833 0.167 0.000
E20-E35 Disorders of other endocrine glands
0.833 0.167 0.000
G43 Migraine
0.829 0.171 0.000
A41 Other septicaemia
0.826 0.174 0.000
M23 Internal derangement of knee
0.825 0.175 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.824 0.176 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.822 0.178 0.000
N17-N19 Renal failure
0.820 0.180 0.000
N36 Other disorders of urethra
0.818 0.182 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.817 0.183 0.000
N30.0 Acute cystitis
0.811 0.189 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.811 0.189 0.000
M17.0 Primary gonarthrosis, bilateral
0.807 0.193 0.000
F31 Bipolar affective disorder
0.807 0.193 0.000
W00-W19 Falls
0.807 0.193 0.000
I47 Paroxysmal tachycardia
0.805 0.194 0.000
M86-M90 Other osteopathies
0.805 0.195 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.803 0.197 0.000
M16.9 Coxarthrosis, unspecified
0.803 0.197 0.000
M77 Other enthesopathies
0.801 0.199 0.000
N30.2 Other chronic cystitis
0.800 0.200 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.799 0.201 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.798 0.202 0.000
N60.8 Other benign mammary dysplasias
0.797 0.203 0.000
I42 Cardiomyopathy
0.796 0.204 0.000
S82 Fracture of lower leg, including ankle
0.796 0.204 0.000
S70-S79 Injuries to the hip and thigh
0.795 0.204 0.000
N32.9 Bladder disorder, unspecified
0.795 0.205 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.793 0.207 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
J90-J94 Other diseases of pleura
0.792 0.208 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.792 0.208 0.000
I74 Arterial embolism and thrombosis
0.791 0.209 0.000
I44.1 Atrioventricular block, second degree
0.790 0.210 0.000
N39.0 Urinary tract infection, site not specified
0.787 0.213 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.784 0.215 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.784 0.216 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.784 0.216 0.000
G30-G32 Other degenerative diseases of the nervous system
0.784 0.216 0.000
N30.8 Other cystitis
0.784 0.216 0.000
D50-D53 Nutritional anaemias
0.779 0.220 0.000
G20-G26 Extrapyramidal and movement disorders
0.778 0.222 0.000
S60-S69 Injuries to the wrist and hand
0.776 0.224 0.000
N39.8 Other specified disorders of urinary system
0.775 0.225 0.000
N64 Other disorders of breast
0.774 0.225 0.000
I35.0 Aortic (valve) stenosis
0.774 0.226 0.000
I08.0 Disorders of both mitral and aortic valves
0.773 0.227 0.000
M05-M14 Inflammatory polyarthropathies
0.773 0.227 0.000
I60-I69 Cerebrovascular diseases
0.773 0.227 0.000
M35.3 Polymyalgia rheumatica
0.770 0.230 0.000
G70-G73 Diseases of myoneural junction and muscle
0.770 0.230 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.768 0.232 0.000
N60.4 Mammary duct ectasia
0.767 0.233 0.000
M79.60 Pain in limb (Multiple sites)
0.766 0.234 0.000
I07.1 Tricuspid insufficiency
0.766 0.234 0.000
I33 Acute and subacute endocarditis
0.764 0.236 0.000
Chapter II Neoplasms
0.764 0.236 0.000
G90-G99 Other disorders of the nervous system
0.763 0.237 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.762 0.238 0.000
E10-E14 Diabetes mellitus
0.760 0.240 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.760 0.240 0.000
Chapter VII Diseases of the eye and adnexa
0.759 0.241 0.000
I30 Acute pericarditis
0.757 0.243 0.000
D69.3 Idiopathic thrombocytopenic purpura
0.756 0.244 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.756 0.244 0.000
Chapter XXII Codes for special purposes
0.755 0.245 0.000
M79.62 Pain in limb (Upper arm)
0.754 0.246 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.754 0.246 0.000
I49.0 Ventricular fibrillation and flutter
0.753 0.247 0.000
B15-B19 Viral hepatitis
0.751 0.249 0.000
D69.6 Thrombocytopenia, unspecified
0.750 0.250 0.000
N32.3 Diverticulum of bladder
0.750 0.250 0.000
J09-J18 Influenza and pneumonia
0.749 0.251 0.000
N39.3 Stress incontinence
0.749 0.251 0.000
A41.9 Septicaemia, unspecified
0.748 0.252 0.000
E78.0 Pure hypercholesterolaemia
0.746 0.254 0.000
T17 Foreign body in respiratory tract
0.744 0.255 0.000
E66.8 Other obesity
0.744 0.256 0.000
I44.2 Atrioventricular block, complete
0.743 0.257 0.000
D80-D89 Certain disorders involving the immune mechanism
0.742 0.258 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.740 0.260 0.000
M20.1 Hallux valgus (acquired)
0.740 0.260 0.000
M48 Other spondylopathies
0.740 0.260 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.739 0.261 0.000
N39.4 Other specified urinary incontinence
0.738 0.262 0.000
M80-M85 Disorders of bone density and structure
0.737 0.263 0.000
J20-J22 Other acute lower respiratory infections
0.736 0.264 0.000
M40-M43 Deforming dorsopathies
0.736 0.264 0.000
R40.2 Coma, unspecified
0.735 0.265 0.000
I44.0 Atrioventricular block, first degree
0.732 0.268 0.000
N10-N16 Renal tubulo-interstitial diseases
0.731 0.269 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.731 0.269 0.000
M46 Other inflammatory spondylopathies
0.730 0.270 0.000
R40.0 Somnolence
0.730 0.270 0.000
N30.1 Interstitial cystitis (chronic)
0.728 0.272 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.726 0.274 0.000
M79.69 Pain in limb (Site unspecified)
0.726 0.274 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.726 0.274 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.724 0.276 0.000
N60.0 Solitary cyst of breast
0.723 0.277 0.000
R47-R49 Symptoms and signs involving speech and voice
0.723 0.277 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.722 0.278 0.000
M72 Fibroblastic disorders
0.719 0.281 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.719 0.281 0.000
M79.64 Pain in limb (Hand)
0.718 0.282 0.000
S50-S59 Injuries to the elbow and forearm
0.718 0.282 0.000
M65-M68 Disorders of synovium and tendon
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I38 Endocarditis, valve unspecified
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.716 0.284 0.000
N34 Urethritis and urethral syndrome
0.716 0.284 0.000
N33 Bladder disorders in diseases classified elsewhere
0.716 0.284 0.000
T18 Foreign body in alimentary tract
0.715 0.285 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.715 0.285 0.000
M71 Other bursopathies
0.715 0.285 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.714 0.286 0.000
M79.9 Soft tissue disorder, unspecified
0.714 0.286 0.000
M79.5 Residual foreign body in soft tissue
0.714 0.286 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.714 0.286 0.000
M79.3 Panniculitis, unspecified
0.714 0.286 0.000
M79.2 Neuralgia and neuritis, unspecified
0.714 0.286 0.000
M79.1 Myalgia
0.714 0.286 0.000
M79.7 Fibromyalgia
0.713 0.287 0.000
T33-T35 Frostbite
0.713 0.287 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.713 0.287 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
T00-T07 Injuries involving multiple body regions
0.713 0.287 0.000
S10-S19 Injuries to the neck
0.713 0.287 0.000
E40-E46 Malnutrition
0.713 0.287 0.000
I51.7 Cardiomegaly
0.712 0.288 0.000
F32 Depressive episode
0.712 0.288 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.711 0.289 0.000
E50-E64 Other nutritional deficiencies
0.711 0.289 0.000
M21 Other acquired deformities of limbs
0.710 0.290 0.000
J93 Pneumothorax
0.710 0.290 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.709 0.291 0.000
I51.8 Other ill-defined heart diseases
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.708 0.292 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.707 0.293 0.000
J95-J99 Other diseases of the respiratory system
0.706 0.294 0.000
I49.9 Cardiac arrhythmia, unspecified
0.706 0.294 0.000
B25-B34 Other viral diseases
0.705 0.295 0.000
Y95 Nosocomial condition
0.704 0.295 0.000
M79.68 Pain in limb (Other)
0.703 0.297 0.000
M79.63 Pain in limb (Forearm)
0.703 0.297 0.000
M79.61 Pain in limb (Shoulder region)
0.703 0.297 0.000
G44 Other headache syndromes
0.703 0.297 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.703 0.297 0.000
I46 Cardiac arrest
0.703 0.297 0.000
E27 Other disorders of adrenal gland
0.703 0.297 0.000
M31 Other necrotising vasculopathies
0.703 0.297 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.702 0.298 0.000
M24 Other specific joint derangements
0.702 0.298 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.702 0.298 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.701 0.299 0.000
N30.4 Irradiation cystitis
0.701 0.299 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.700 0.299 0.000
M34 Systemic sclerosis
0.700 0.299 0.000
M33 Dermatopolymyositis
0.700 0.299 0.000
M32 Systemic lupus erythematosus
0.700 0.299 0.000
M30 Polyarteritis nodosa and related conditions
0.700 0.299 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.700 0.300 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.700 0.300 0.000
G43.9 Migraine, unspecified
0.700 0.300 0.000
E78.8 Other disorders of lipoprotein metabolism
0.699 0.301 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.699 0.301 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.698 0.302 0.000
I35.1 Aortic (valve) insufficiency
0.698 0.302 0.000
J60-J70 Lung diseases due to external agents
0.697 0.303 0.000
I31.8 Other specified diseases of pericardium
0.696 0.304 0.000
I31.2 Haemopericardium, not elsewhere classified
0.696 0.304 0.000
I31.1 Chronic constrictive pericarditis
0.696 0.304 0.000
I31.0 Chronic adhesive pericarditis
0.696 0.304 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.696 0.304 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.696 0.304 0.000
B99-B99 Other infectious diseases
0.693 0.306 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.693 0.306 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.693 0.306 0.000
B65-B83 Helminthiases
0.693 0.306 0.000
B50-B64 Protozoal diseases
0.693 0.306 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.693 0.306 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.693 0.306 0.000
A80-A89 Viral infections of the central nervous system
0.693 0.306 0.000
A75-A79 Rickettsioses
0.693 0.306 0.000
A70-A74 Other diseases caused by chlamydiae
0.693 0.306 0.000
A65-A69 Other spirochaetal diseases
0.693 0.306 0.000
A20-A28 Certain zoonotic bacterial diseases
0.693 0.306 0.000
A15-A19 Tuberculosis
0.693 0.306 0.000
E67 Other hyperalimentation
0.692 0.308 0.000
E68 Sequelae of hyperalimentation
0.692 0.308 0.000
E65 Localised adiposity
0.692 0.308 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.692 0.308 0.000
G41 Status epilepticus
0.692 0.308 0.000
I78 Diseases of capillaries
0.691 0.309 0.000
R41.3 Other amnesia
0.690 0.310 0.000
I08.1 Disorders of both mitral and tricuspid valves
0.690 0.310 0.000
I72 Other aneurysm
0.688 0.312 0.000
M17.9 Gonarthrosis, unspecified
0.687 0.313 0.000
W20-W49 Exposure to inanimate mechanical forces
0.687 0.313 0.000
I35.8 Other aortic valve disorders
0.687 0.313 0.000
E78.5 Hyperlipidaemia, unspecified
0.687 0.313 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.686 0.314 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.685 0.314 0.000
I60 Subarachnoid haemorrhage
0.685 0.315 0.000
D00-D09 In situ neoplasms
0.682 0.318 0.000
S82.8 Fractures of other parts of lower leg
0.682 0.318 0.000
M20.3 Other deformity of hallux (acquired)
0.680 0.320 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.680 0.320 0.000
I09 Other rheumatic heart diseases
0.680 0.320 0.000
I06 Rheumatic aortic valve diseases
0.680 0.320 0.000
I05 Rheumatic mitral valve diseases
0.680 0.320 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.680 0.320 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.678 0.322 0.000
I70 Atherosclerosis
0.678 0.322 0.000
I73 Other peripheral vascular diseases
0.677 0.322 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.677 0.323 0.000
E66.1 Drug-induced obesity
0.677 0.323 0.000
E66.0 Obesity due to excess calories
0.677 0.323 0.000
E88 Other metabolic disorders
0.675 0.325 0.000
E85 Amyloidosis
0.675 0.325 0.000
E84 Cystic fibrosis
0.675 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.675 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.675 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.675 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.675 0.325 0.000
E74 Other disorders of carbohydrate metabolism
0.675 0.325 0.000
E73 Lactose intolerance
0.675 0.325 0.000
E72 Other disorders of amino-acid metabolism
0.675 0.325 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.675 0.325 0.000
E70 Disorders of aromatic amino-acid metabolism
0.675 0.325 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.675 0.325 0.000
S27 Injury of other and unspecified intrathoracic organs
0.673 0.327 0.000
N18 Chronic renal failure
0.672 0.328 0.000
W19 Unspecified fall
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.669 0.331 0.000
M79.88 Other specified soft tissue disorders (Other)
0.669 0.331 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.669 0.331 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.669 0.331 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.669 0.331 0.000
M79.80 Other specified soft tissue disorders (Multiple sites)
0.669 0.331 0.000
T66-T78 Other and unspecified effects of external causes
0.668 0.331 0.000
R25 Abnormal involuntary movements
0.668 0.332 0.000
M79.08 Rheumatism, unspecified (Other)
0.668 0.332 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.668 0.332 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.668 0.332 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.668 0.332 0.000
M79.04 Rheumatism, unspecified (Hand)
0.668 0.332 0.000
M79.03 Rheumatism, unspecified (Forearm)
0.668 0.332 0.000
M79.02 Rheumatism, unspecified (Upper arm)
0.668 0.332 0.000
M79.01 Rheumatism, unspecified (Shoulder region)
0.668 0.332 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.668 0.332 0.000
D68 Other coagulation defects
0.667 0.333 0.000
I45 Other conduction disorders
0.667 0.333 0.000
S42 Fracture of shoulder and upper arm
0.666 0.334 0.000
D50 Iron deficiency anaemia
0.666 0.334 0.000
N32.4 Rupture of bladder, nontraumatic
0.666 0.334 0.000
N32.2 Vesical fistula, not elsewhere classified
0.666 0.334 0.000
N32.1 Vesicointestinal fistula
0.666 0.334 0.000
C64-C68 Malignant neoplasms of urinary tract
0.665 0.335 0.000
N39.2 Orthostatic proteinuria, unspecified
0.664 0.336 0.000
N39.1 Persistent proteinuria, unspecified
0.664 0.336 0.000
M15 Polyarthrosis
0.664 0.336 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.663 0.337 0.000
J18 Pneumonia, organism unspecified
0.662 0.338 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.660 0.340 0.000
I51.9 Heart disease, unspecified
0.659 0.341 0.000
R80 Isolated proteinuria
0.657 0.343 0.000
E14 Unspecified diabetes mellitus
0.656 0.344 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.656 0.344 0.000
I44.6 Other and unspecified fascicular block
0.656 0.344 0.000
I44.5 Left posterior fascicular block
0.656 0.344 0.000
I44.4 Left anterior fascicular block
0.656 0.344 0.000
I44.3 Other and unspecified atrioventricular block
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.655 0.345 0.000
A49 Bacterial infection of unspecified site
0.655 0.345 0.000
A41.0 Septicaemia due to Staphylococcus aureus
0.655 0.345 0.000
S82.0 Fracture of patella
0.654 0.346 0.000
H55-H59 Other disorders of eye and adnexa
0.654 0.346 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
G43.1 Migraine with aura [classical migraine]
0.653 0.347 0.000
B35-B49 Mycoses
0.653 0.347 0.000
I50.1 Left ventricular failure
0.653 0.347 0.000
F99-F99 Unspecified mental disorder
0.653 0.347 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.653 0.347 0.000
F70-F79 Mental retardation
0.653 0.347 0.000
I69 Sequelae of cerebrovascular disease
0.653 0.347 0.000
M20.0 Deformity of finger(s)
0.652 0.348 0.000
G40.8 Other epilepsy
0.652 0.348 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.652 0.348 0.000
G40.5 Special epileptic syndromes
0.652 0.348 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.652 0.348 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.652 0.348 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.652 0.348 0.000
T17.9 Foreign body in respiratory tract, part unspecified
0.651 0.349 0.000
I74.5 Embolism and thrombosis of iliac artery
0.650 0.350 0.000
M16.3 Other dysplastic coxarthrosis
0.649 0.350 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
I47.2 Ventricular tachycardia
0.649 0.351 0.000
N60.9 Benign mammary dysplasia, unspecified
0.648 0.351 0.000
N60.2 Fibroadenosis of breast
0.648 0.351 0.000
Q60-Q64 Congenital malformations of the urinary system
0.648 0.352 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.647 0.353 0.000
H30-H36 Disorders of choroid and retina
0.647 0.353 0.000
T51 Toxic effect of alcohol
0.647 0.353 0.000
I77 Other disorders of arteries and arterioles
0.646 0.354 0.000
N36.2 Urethral caruncle
0.646 0.354 0.000
M23.4 Loose body in knee
0.645 0.355 0.000
I44.7 Left bundle-branch block, unspecified
0.644 0.356 0.000
X60-X84 Intentional self-harm
0.644 0.356 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.644 0.356 0.000
E89.0 Postprocedural hypothyroidism
0.644 0.356 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.643 0.357 0.000
J90 Pleural effusion, not elsewhere classified
0.643 0.357 0.000
S70 Superficial injury of hip and thigh
0.643 0.357 0.000
N36.8 Other specified disorders of urethra
0.643 0.357 0.000
V10-V19 Pedal cyclist injured in transport accident
0.642 0.357 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
Y35-Y36 Legal intervention and operations of war
0.642 0.358 0.000
Y10-Y34 Event of undetermined intent
0.642 0.358 0.000
Y00-Y09 Assault
0.642 0.358 0.000
X85-X99 Assault
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.642 0.358 0.000
X30-X39 Exposure to forces of nature
0.642 0.358 0.000
X20-X29 Contact with venomous animals and plants
0.642 0.358 0.000
X10-X19 Contact with heat and hot substances
0.642 0.358 0.000
X00-X09 Exposure to smoke, fire and flames
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.642 0.358 0.000
W75-W84 Other accidental threats to breathing
0.642 0.358 0.000
W65-W74 Accidental drowning and submersion
0.642 0.358 0.000
W50-W64 Exposure to animate mechanical forces
0.642 0.358 0.000
V98-V99 Other and unspecified transport accidents
0.642 0.358 0.000
V95-V97 Air and space transport accidents
0.642 0.358 0.000
V90-V94 Water transport accidents
0.642 0.358 0.000
V80-V89 Other land transport accidents
0.642 0.358 0.000
V70-V79 Bus occupant injured in transport accident
0.642 0.358 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.642 0.358 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.642 0.358 0.000
V40-V49 Car occupant injured in transport accident
0.642 0.358 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.642 0.358 0.000
V01-V09 Pedestrian injured in transport accident
0.642 0.358 0.000
G30 Alzheimer's disease
0.642 0.358 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.642 0.358 0.000
N99-N99 Other disorders of the genitourinary system
0.641 0.358 0.000
R46 Symptoms and signs involving appearance and behaviour
0.640 0.360 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.640 0.360 0.000
R43 Disturbances of smell and taste
0.640 0.360 0.000
S20 Superficial injury of thorax
0.640 0.360 0.000
J22 Unspecified acute lower respiratory infection
0.640 0.360 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.640 0.360 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.640 0.360 0.000
W08 Fall involving other furniture
0.640 0.360 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.639 0.360 0.000
I35.9 Aortic valve disorder, unspecified
0.639 0.361 0.000
I10-I15 Hypertensive diseases
0.638 0.362 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.638 0.362 0.000
S62 Fracture at wrist and hand level
0.637 0.363 0.000
A48 Other bacterial diseases, not elsewhere classified
0.636 0.364 0.000
A44 Bartonellosis
0.636 0.364 0.000
A43 Nocardiosis
0.636 0.364 0.000
A42 Actinomycosis
0.636 0.364 0.000
A40 Streptococcal septicaemia
0.636 0.364 0.000
A39 Meningococcal infection
0.636 0.364 0.000
A37 Whooping cough
0.636 0.364 0.000
A36 Diphtheria
0.636 0.364 0.000
A32 Listeriosis
0.636 0.364 0.000
A31 Infection due to other mycobacteria
0.636 0.364 0.000
A30 Leprosy [Hansen's disease]
0.636 0.364 0.000
A46 Erysipelas
0.636 0.364 0.000
A38 Scarlet fever
0.636 0.364 0.000
A35 Other tetanus
0.636 0.364 0.000
A34 Obstetrical tetanus
0.636 0.364 0.000
A33 Tetanus neonatorum
0.636 0.364 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.636 0.364 0.000
E80.6 Other disorders of bilirubin metabolism
0.636 0.364 0.000
E80.5 Crigler-Najjar syndrome
0.636 0.364 0.000
E80.3 Defects of catalase and peroxydase
0.636 0.364 0.000
E80.2 Other porphyria
0.636 0.364 0.000
E80.1 Porphyria cutanea tarda
0.636 0.364 0.000
E80.0 Hereditary erythropoietic porphyria
0.636 0.364 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.635 0.365 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.635 0.365 0.000
G45.3 Amaurosis fugax
0.635 0.365 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.635 0.365 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.635 0.365 0.000
G45.0 Vertebro-basilar artery syndrome
0.635 0.365 0.000
G93 Other disorders of brain
0.633 0.367 0.000
D67 Hereditary factor IX deficiency
0.633 0.367 0.000
D66 Hereditary factor VIII deficiency
0.633 0.367 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.633 0.367 0.000
N35 Urethral stricture
0.633 0.367 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.633 0.367 0.000
F31.9 Bipolar affective disorder, unspecified
0.633 0.367 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.632 0.368 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.632 0.368 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.632 0.368 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.632 0.368 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.632 0.368 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.632 0.368 0.000
I71.0 Dissection of aorta [any part]
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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