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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117708929
log Bayes Factor = 24.4858
Chromosome 6   position 124,879,601  (GRCh37) Explore rs117708929 on Ensembl!
Variant rs117708929 is part of Cluster X0081

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.998 0.002 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.998 0.002 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.997 0.003 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.997 0.003 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.994 0.006 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.993 0.007 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
R10 Abdominal and pelvic pain
0.991 0.009 0.000
R10.4 Other and unspecified abdominal pain
0.989 0.011 0.000
E10-E14 Diabetes mellitus
0.987 0.013 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.982 0.018 0.000
T81 Complications of procedures, not elsewhere classified
0.982 0.018 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.979 0.021 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
E10 Insulin-dependent diabetes mellitus
0.976 0.024 0.000
Chapter VII Diseases of the eye and adnexa
0.974 0.026 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.973 0.027 0.000
J30-J39 Other diseases of upper respiratory tract
0.973 0.027 0.000
I60-I69 Cerebrovascular diseases
0.968 0.032 0.000
M20-M25 Other joint disorders
0.968 0.032 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.965 0.035 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.962 0.038 0.000
J34 Other disorders of nose and nasal sinuses
0.958 0.042 0.000
K65-K67 Diseases of peritoneum
0.958 0.042 0.000
H30-H36 Disorders of choroid and retina
0.956 0.044 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.955 0.045 0.000
Chapter VI Diseases of the nervous system
0.955 0.045 0.000
Chapter I Certain infectious and parasitic diseases
0.953 0.047 0.000
E10.9 Without complications
0.950 0.050 0.000
I10-I15 Hypertensive diseases
0.948 0.052 0.000
Chapter V Mental and behavioural disorders
0.947 0.053 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.945 0.055 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.943 0.057 0.000
Z12 Special screening examination for neoplasms
0.942 0.058 0.000
M70-M79 Other soft tissue disorders
0.936 0.064 0.000
Chapter XIV Diseases of the genitourinary system
0.934 0.066 0.000
I10 Essential (primary) hypertension
0.933 0.067 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.929 0.071 0.000
H33 Retinal detachments and breaks
0.928 0.072 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.924 0.076 0.000
Y43 Primarily systemic agents
0.924 0.076 0.000
M05-M14 Inflammatory polyarthropathies
0.922 0.078 0.000
K66 Other disorders of peritoneum
0.922 0.078 0.000
M45-M49 Spondylopathies
0.919 0.081 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.917 0.083 0.000
K81 Cholecystitis
0.917 0.083 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.916 0.084 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.912 0.088 0.000
M25 Other joint disorders, not elsewhere classified
0.911 0.089 0.000
J34.2 Deviated nasal septum
0.906 0.094 0.000
Chapter VIII Diseases of the ear and mastoid process
0.905 0.095 0.000
A00-A09 Intestinal infectious diseases
0.905 0.095 0.000
Z12.1 Special screening examination for neoplasm of intestinal tract
0.905 0.095 0.000
Z01.8 Other specified special examinations
0.903 0.097 0.000
R07 Pain in throat and chest
0.901 0.099 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.899 0.101 0.000
K66.0 Peritoneal adhesions
0.896 0.104 0.000
R10.2 Pelvic and perineal pain
0.895 0.105 0.000
K70-K77 Diseases of liver
0.892 0.108 0.000
K86 Other diseases of pancreas
0.890 0.110 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.888 0.112 0.000
Z91.5 Personal history of self-harm
0.888 0.112 0.000
M50-M54 Other dorsopathies
0.887 0.113 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.886 0.114 0.000
N20-N23 Urolithiasis
0.886 0.114 0.000
K90-K93 Other diseases of the digestive system
0.884 0.116 0.000
J34.3 Hypertrophy of nasal turbinates
0.884 0.116 0.000
R00 Abnormalities of heart beat
0.882 0.118 0.000
I67 Other cerebrovascular diseases
0.880 0.120 0.000
N10-N16 Renal tubulo-interstitial diseases
0.876 0.124 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.873 0.127 0.000
R06 Abnormalities of breathing
0.871 0.129 0.000
K83 Other diseases of biliary tract
0.868 0.132 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.867 0.133 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.866 0.134 0.000
G40-G47 Episodic and paroxysmal disorders
0.865 0.135 0.000
D70 Agranulocytosis
0.865 0.135 0.000
I69 Sequelae of cerebrovascular disease
0.864 0.136 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.861 0.139 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.860 0.140 0.000
F30-F39 Mood [affective] disorders
0.860 0.140 0.000
T51 Toxic effect of alcohol
0.856 0.144 0.000
Y43.3 Other antineoplastic drugs
0.855 0.145 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.854 0.146 0.000
W20-W49 Exposure to inanimate mechanical forces
0.854 0.146 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.854 0.146 0.000
Z80 Family history of malignant neoplasm
0.853 0.147 0.000
E10.1 With ketoacidosis
0.850 0.150 0.000
R07.3 Other chest pain
0.849 0.151 0.000
H33.0 Retinal detachment with retinal break
0.848 0.152 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.848 0.152 0.000
H53-H54 Visual disturbances and blindness
0.846 0.154 0.000
E00-E07 Disorders of thyroid gland
0.846 0.154 0.000
E14 Unspecified diabetes mellitus
0.845 0.155 0.000
K08 Other disorders of teeth and supporting structures
0.845 0.155 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.843 0.157 0.000
J95-J99 Other diseases of the respiratory system
0.842 0.158 0.000
M25.5 Pain in joint
0.841 0.159 0.000
Z89 Acquired absence of limb
0.840 0.160 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.838 0.162 0.000
N99-N99 Other disorders of the genitourinary system
0.837 0.163 0.000
I67.8 Other specified cerebrovascular diseases
0.836 0.164 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.833 0.167 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.833 0.167 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.833 0.167 0.000
H36 Retinal disorders in diseases classified elsewhere
0.832 0.168 0.000
Z03.4 Observation for suspected myocardial infarction
0.831 0.169 0.000
M91-M94 Chondropathies
0.830 0.170 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.828 0.171 0.000
N13 Obstructive and reflux uropathy
0.828 0.172 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.827 0.173 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.826 0.174 0.000
M75 Shoulder lesions
0.825 0.175 0.000
M47 Spondylosis
0.825 0.175 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.825 0.175 0.000
M13 Other arthritis
0.824 0.176 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.824 0.176 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.819 0.181 0.000
R50-R69 General symptoms and signs
0.818 0.182 0.000
K50-K52 Noninfective enteritis and colitis
0.817 0.183 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.817 0.183 0.000
K82 Other diseases of gallbladder
0.814 0.186 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.814 0.186 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.812 0.188 0.000
G47 Sleep disorders
0.811 0.189 0.000
J90-J94 Other diseases of pleura
0.807 0.193 0.000
H65-H75 Diseases of middle ear and mastoid
0.806 0.194 0.000
Z83 Family history of other specific disorders
0.805 0.194 0.000
H33.2 Serous retinal detachment
0.805 0.195 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.804 0.196 0.000
Z97 Presence of other devices
0.804 0.196 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.802 0.198 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.800 0.200 0.000
T51.0 Ethanol
0.799 0.201 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.798 0.202 0.000
Z98 Other postsurgical states
0.798 0.202 0.000
M35 Other systemic involvement of connective tissue
0.798 0.202 0.000
S20-S29 Injuries to the thorax
0.798 0.202 0.000
M65-M68 Disorders of synovium and tendon
0.797 0.203 0.000
I63 Cerebral infarction
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.795 0.205 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.794 0.206 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.793 0.207 0.000
E10.3 With ophthalmic complications
0.793 0.207 0.000
R06.5 Mouth breathing
0.792 0.208 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.792 0.208 0.000
N25-N29 Other disorders of kidney and ureter
0.791 0.209 0.000
R00.1 Bradycardia, unspecified
0.791 0.209 0.000
R18 Ascites
0.791 0.209 0.000
H33.3 Retinal breaks without detachment
0.791 0.209 0.000
N23 Unspecified renal colic
0.789 0.211 0.000
K81.0 Acute cholecystitis
0.789 0.211 0.000
M54 Dorsalgia
0.789 0.211 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.788 0.212 0.000
W00-W19 Falls
0.787 0.213 0.000
E50-E64 Other nutritional deficiencies
0.784 0.216 0.000
N00-N08 Glomerular diseases
0.784 0.216 0.000
R16.1 Splenomegaly, not elsewhere classified
0.784 0.216 0.000
B35-B49 Mycoses
0.784 0.216 0.000
K08.3 Retained dental root
0.783 0.217 0.000
R00.0 Tachycardia, unspecified
0.783 0.217 0.000
R42 Dizziness and giddiness
0.783 0.217 0.000
K86.1 Other chronic pancreatitis
0.783 0.217 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.782 0.218 0.000
J20-J22 Other acute lower respiratory infections
0.779 0.221 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.778 0.222 0.000
M10 Gout
0.778 0.222 0.000
T42.4 Benzodiazepines
0.777 0.223 0.000
S70-S79 Injuries to the hip and thigh
0.776 0.224 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.776 0.224 0.000
K81.9 Cholecystitis, unspecified
0.776 0.224 0.000
K85 Acute pancreatitis
0.776 0.224 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.775 0.225 0.000
X60-X84 Intentional self-harm
0.775 0.225 0.000
R30-R39 Symptoms and signs involving the urinary system
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.774 0.226 0.000
Z01.6 Radiological examination, not elsewhere classified
0.772 0.228 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.772 0.228 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.771 0.229 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.771 0.229 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.770 0.229 0.000
V10-V19 Pedal cyclist injured in transport accident
0.770 0.230 0.000
N20 Calculus of kidney and ureter
0.769 0.231 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.768 0.232 0.000
K74 Fibrosis and cirrhosis of liver
0.768 0.232 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.768 0.232 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.767 0.233 0.000
Chapter XXII Codes for special purposes
0.766 0.234 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.765 0.235 0.000
Y43.4 Immunosuppressive agents
0.764 0.236 0.000
F60-F69 Disorders of adult personality and behaviour
0.764 0.236 0.000
J35 Chronic diseases of tonsils and adenoids
0.763 0.237 0.000
E65-E68 Obesity and other hyperalimentation
0.761 0.239 0.000
R14 Flatulence and related conditions
0.761 0.239 0.000
F33 Recurrent depressive disorder
0.760 0.240 0.000
T82.1 Mechanical complication of cardiac electronic device
0.760 0.240 0.000
R53 Malaise and fatigue
0.759 0.241 0.000
A04 Other bacterial intestinal infections
0.757 0.243 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.756 0.244 0.000
K91.8 Other postprocedural disorders of digestive system, not elsewhere classified
0.756 0.244 0.000
Z88.2 Personal history of allergy to sulphonamides
0.755 0.245 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.755 0.245 0.000
M47.8 Other spondylosis
0.755 0.245 0.000
M13.9 Arthritis, unspecified
0.754 0.246 0.000
Z00.0 General medical examination
0.753 0.246 0.000
Z94 Transplanted organ and tissue status
0.753 0.247 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.753 0.247 0.000
M40-M43 Deforming dorsopathies
0.753 0.247 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.753 0.247 0.000
M22 Disorders of patella
0.750 0.249 0.000
Z04 Examination and observation for other reasons
0.750 0.250 0.000
Z93 Artificial opening status
0.749 0.251 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.747 0.253 0.000
M25.7 Osteophyte
0.747 0.253 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.747 0.253 0.000
T79-T79 Certain early complications of trauma
0.745 0.255 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.745 0.255 0.000
H36.0 Diabetic retinopathy
0.744 0.256 0.000
Z01.4 Gynaecological examination (general)(routine)
0.743 0.257 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.743 0.257 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.742 0.258 0.000
Y45.0 Opioids and related analgesics
0.741 0.259 0.000
O00-O08 Pregnancy with abortive outcome
0.741 0.259 0.000
D50-D53 Nutritional anaemias
0.741 0.259 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.741 0.259 0.000
R07.4 Chest pain, unspecified
0.741 0.259 0.000
R47-R49 Symptoms and signs involving speech and voice
0.741 0.259 0.000
K65 Peritonitis
0.740 0.260 0.000
J00-J06 Acute upper respiratory infections
0.740 0.260 0.000
W44 Foreign body entering into or through eye or natural orifice
0.740 0.260 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.739 0.261 0.000
K81.1 Chronic cholecystitis
0.739 0.261 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.738 0.262 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.738 0.262 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.737 0.263 0.000
G62 Other polyneuropathies
0.737 0.263 0.000
Y57 Other and unspecified drugs and medicaments
0.737 0.263 0.000
R13 Dysphagia
0.737 0.263 0.000
S90-S99 Injuries to the ankle and foot
0.735 0.265 0.000
K86.8 Other specified diseases of pancreas
0.734 0.265 0.000
S60-S69 Injuries to the wrist and hand
0.734 0.266 0.000
J98 Other respiratory disorders
0.734 0.266 0.000
S80-S89 Injuries to the knee and lower leg
0.733 0.267 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.733 0.267 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.732 0.268 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.732 0.268 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.732 0.268 0.000
G47.9 Sleep disorder, unspecified
0.732 0.268 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.731 0.269 0.000
J09-J18 Influenza and pneumonia
0.730 0.270 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.730 0.270 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.729 0.271 0.000
I60 Subarachnoid haemorrhage
0.729 0.271 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.728 0.272 0.000
M75.4 Impingement syndrome of shoulder
0.727 0.273 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.727 0.273 0.000
D72 Other disorders of white blood cells
0.726 0.274 0.000
F99-F99 Unspecified mental disorder
0.725 0.275 0.000
T40.2 Other opioids
0.725 0.275 0.000
F31 Bipolar affective disorder
0.724 0.275 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.724 0.276 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.724 0.276 0.000
T66-T78 Other and unspecified effects of external causes
0.724 0.276 0.000
K83.0 Cholangitis
0.724 0.276 0.000
R03.1 Nonspecific low blood-pressure reading
0.722 0.278 0.000
K04 Diseases of pulp and periapical tissues
0.722 0.278 0.000
M54.9 Dorsalgia, unspecified
0.721 0.279 0.000
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung
0.720 0.280 0.000
E20-E35 Disorders of other endocrine glands
0.720 0.280 0.000
M20 Acquired deformities of fingers and toes
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
S10-S19 Injuries to the neck
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
M23 Internal derangement of knee
0.716 0.284 0.000
E05.9 Thyrotoxicosis, unspecified
0.716 0.284 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.716 0.284 0.000
Z84 Family history of other conditions
0.715 0.284 0.000
Z81 Family history of mental and behavioural disorders
0.715 0.284 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
T86 Failure and rejection of transplanted organs and tissues
0.715 0.285 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
Y35-Y36 Legal intervention and operations of war
0.715 0.285 0.000
Y10-Y34 Event of undetermined intent
0.715 0.285 0.000
Y00-Y09 Assault
0.715 0.285 0.000
X85-X99 Assault
0.715 0.285 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.715 0.285 0.000
X50-X57 Overexertion, travel and privation
0.715 0.285 0.000
X30-X39 Exposure to forces of nature
0.715 0.285 0.000
X20-X29 Contact with venomous animals and plants
0.715 0.285 0.000
X10-X19 Contact with heat and hot substances
0.715 0.285 0.000
X00-X09 Exposure to smoke, fire and flames
0.715 0.285 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.715 0.285 0.000
W75-W84 Other accidental threats to breathing
0.715 0.285 0.000
W65-W74 Accidental drowning and submersion
0.715 0.285 0.000
W50-W64 Exposure to animate mechanical forces
0.715 0.285 0.000
V98-V99 Other and unspecified transport accidents
0.715 0.285 0.000
V95-V97 Air and space transport accidents
0.715 0.285 0.000
V90-V94 Water transport accidents
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
V70-V79 Bus occupant injured in transport accident
0.715 0.285 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.715 0.285 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.715 0.285 0.000
V40-V49 Car occupant injured in transport accident
0.715 0.285 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.715 0.285 0.000
V20-V29 Motorcycle rider injured in transport accident
0.715 0.285 0.000
V01-V09 Pedestrian injured in transport accident
0.715 0.285 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.715 0.285 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.715 0.285 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.715 0.285 0.000
K12 Stomatitis and related lesions
0.714 0.286 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.714 0.286 0.000
H35 Other retinal disorders
0.713 0.287 0.000
M77 Other enthesopathies
0.713 0.287 0.000
Z10 Routine general health check-up of defined subpopulation
0.712 0.288 0.000
J60-J70 Lung diseases due to external agents
0.712 0.288 0.000
M48 Other spondylopathies
0.711 0.289 0.000
F80-F89 Disorders of psychological development
0.711 0.289 0.000
A08 Viral and other specified intestinal infections
0.710 0.290 0.000
E14.9 Without complications
0.710 0.290 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.710 0.290 0.000
R12 Heartburn
0.710 0.290 0.000
H80-H83 Diseases of inner ear
0.709 0.291 0.000
D73 Diseases of spleen
0.709 0.291 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.709 0.291 0.000
R06.2 Wheezing
0.709 0.291 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.709 0.291 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.708 0.292 0.000
R17 Unspecified jaundice
0.708 0.292 0.000
M80-M85 Disorders of bone density and structure
0.708 0.292 0.000
E13 Other specified diabetes mellitus
0.707 0.292 0.000
E12 Malnutrition-related diabetes mellitus
0.707 0.292 0.000
K76 Other diseases of liver
0.707 0.293 0.000
J39 Other diseases of upper respiratory tract
0.706 0.294 0.000
J38.3 Other diseases of vocal cords
0.705 0.294 0.000
M72 Fibroblastic disorders
0.705 0.294 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.705 0.295 0.000
N20.0 Calculus of kidney
0.705 0.295 0.000
Y59 Other and unspecified vaccines and biological substances
0.704 0.296 0.000
Y58 Bacterial vaccines
0.704 0.296 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.704 0.296 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.704 0.296 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.704 0.296 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.704 0.296 0.000
Y52 Agents primarily affecting the cardiovascular system
0.704 0.296 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.704 0.296 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.704 0.296 0.000
Y48 Anaesthetics and therapeutic gases
0.704 0.296 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.704 0.296 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.704 0.296 0.000
Y44 Agents primarily affecting blood constituents
0.704 0.296 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.704 0.296 0.000
T81.9 Unspecified complication of procedure
0.704 0.296 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.704 0.296 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.704 0.296 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.704 0.296 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.704 0.296 0.000
J92 Pleural plaque
0.704 0.296 0.000
D80-D89 Certain disorders involving the immune mechanism
0.703 0.296 0.000
Z80.9 Family history of malignant neoplasm, unspecified
0.703 0.297 0.000
H53 Visual disturbances
0.703 0.297 0.000
H43-H45 Disorders of vitreous body and globe
0.701 0.299 0.000
Y40 Systemic antibiotics
0.701 0.299 0.000
R16.0 Hepatomegaly, not elsewhere classified
0.700 0.300 0.000
H90-H95 Other disorders of ear
0.700 0.300 0.000
G30-G32 Other degenerative diseases of the nervous system
0.700 0.300 0.000
G47.3 Sleep apnoea
0.700 0.300 0.000
N13.5 Kinking and stricture of ureter without hydronephrosis
0.700 0.300 0.000
J38.7 Other diseases of larynx
0.700 0.300 0.000
E10.8 With unspecified complications
0.700 0.300 0.000
E10.7 With multiple complications
0.700 0.300 0.000
E10.6 With other specified complications
0.700 0.300 0.000
E10.5 With peripheral circulatory complications
0.700 0.300 0.000
E10.4 With neurological complications
0.700 0.300 0.000
E10.2 With renal complications
0.700 0.300 0.000
E10.0 With coma
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.699 0.301 0.000
M31 Other necrotising vasculopathies
0.699 0.301 0.000
K91.4 Colostomy and enterostomy malfunction
0.699 0.301 0.000
T18 Foreign body in alimentary tract
0.699 0.301 0.000
G44 Other headache syndromes
0.699 0.301 0.000
H55-H59 Other disorders of eye and adnexa
0.699 0.301 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.699 0.301 0.000
H10-H13 Disorders of conjunctiva
0.699 0.301 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.698 0.301 0.000
M25.50 Pain in joint (Multiple sites)
0.698 0.302 0.000
K83.1 Obstruction of bile duct
0.698 0.302 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
J37 Chronic laryngitis and laryngotracheitis
0.697 0.303 0.000
K75 Other inflammatory liver diseases
0.697 0.303 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.697 0.303 0.000
M25.53 Pain in joint (Forearm)
0.697 0.303 0.000
I69.3 Sequelae of cerebral infarction
0.697 0.303 0.000
H66 Suppurative and unspecified otitis media
0.696 0.304 0.000
M47.82 Other spondylosis (Cervical region)
0.696 0.304 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.696 0.304 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
J38.0 Paralysis of vocal cords and larynx
0.695 0.305 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.694 0.306 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.694 0.306 0.000
I62 Other nontraumatic intracranial haemorrhage
0.694 0.306 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.694 0.306 0.000
M34 Systemic sclerosis
0.694 0.306 0.000
M33 Dermatopolymyositis
0.694 0.306 0.000
M32 Systemic lupus erythematosus
0.694 0.306 0.000
M30 Polyarteritis nodosa and related conditions
0.694 0.306 0.000
M24 Other specific joint derangements
0.694 0.306 0.000
M21 Other acquired deformities of limbs
0.694 0.306 0.000
M46 Other inflammatory spondylopathies
0.694 0.306 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.694 0.306 0.000
N21 Calculus of lower urinary tract
0.694 0.306 0.000
R25 Abnormal involuntary movements
0.694 0.306 0.000
H54 Blindness and low vision
0.693 0.307 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.692 0.308 0.000
K52 Other non-infective gastro-enteritis and colitis
0.692 0.308 0.000
M45 Ankylosing spondylitis
0.690 0.310 0.000
D75 Other diseases of blood and blood-forming organs
0.690 0.310 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.689 0.311 0.000
R29.6 Tendency to fall, not elsewhere classified
0.689 0.311 0.000
F33.9 Recurrent depressive disorder, unspecified
0.689 0.311 0.000
K07 Dentofacial anomalies [including malocclusion]
0.688 0.312 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.688 0.312 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.688 0.312 0.000
T39.1 4-Aminophenol derivatives
0.687 0.313 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.687 0.313 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.687 0.313 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.687 0.313 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.685 0.315 0.000
H31 Other disorders of choroid
0.685 0.315 0.000
H30 Chorioretinal inflammation
0.685 0.315 0.000
Z01.9 Special examination, unspecified
0.685 0.315 0.000
Z01.7 Laboratory examination
0.685 0.315 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.685 0.315 0.000
Z01.3 Examination of blood pressure
0.685 0.315 0.000
Z01.2 Dental examination
0.685 0.315 0.000
Z01.1 Examination of ears and hearing
0.685 0.315 0.000
Z01.0 Examination of eyes and vision
0.685 0.315 0.000
G70-G73 Diseases of myoneural junction and muscle
0.685 0.315 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.685 0.315 0.000
M35.0 Sicca syndrome [Sjogren]
0.685 0.315 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.684 0.316 0.000
B99-B99 Other infectious diseases
0.683 0.317 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.683 0.317 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.683 0.317 0.000
B65-B83 Helminthiases
0.683 0.317 0.000
B50-B64 Protozoal diseases
0.683 0.317 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.683 0.317 0.000
B15-B19 Viral hepatitis
0.683 0.317 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.683 0.317 0.000
A80-A89 Viral infections of the central nervous system
0.683 0.317 0.000
A75-A79 Rickettsioses
0.683 0.317 0.000
A70-A74 Other diseases caused by chlamydiae
0.683 0.317 0.000
A65-A69 Other spirochaetal diseases
0.683 0.317 0.000
A20-A28 Certain zoonotic bacterial diseases
0.683 0.317 0.000
A15-A19 Tuberculosis
0.683 0.317 0.000
H65 Nonsuppurative otitis media
0.683 0.317 0.000
R01 Cardiac murmurs and other cardiac sounds
0.683 0.317 0.000
N99.3 Prolapse of vaginal vault after hysterectomy
0.683 0.317 0.000
F43 Reaction to severe stress, and adjustment disorders
0.682 0.318 0.000
Z80.4 Family history of malignant neoplasm of genital organs
0.682 0.318 0.000
R20 Disturbances of skin sensation
0.682 0.318 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.681 0.319 0.000
R06.4 Hyperventilation
0.681 0.319 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.681 0.319 0.000
M25.4 Effusion of joint
0.681 0.319 0.000
I15 Secondary hypertension
0.680 0.320 0.000
I13 Hypertensive heart and renal disease
0.680 0.320 0.000
I11 Hypertensive heart disease
0.680 0.320 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.679 0.321 0.000
F70-F79 Mental retardation
0.679 0.321 0.000
Z89.6 Acquired absence of leg above knee
0.678 0.322 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.678 0.322 0.000
Z91.7 Personal history of female genital mutilation
0.678 0.322 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.678 0.322 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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