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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117749488
log Bayes Factor = 32.7012
Chromosome 11   position 48,629,423  (GRCh37) Explore rs117749488 on Ensembl!
Variant rs117749488 is part of Cluster X0327

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
J44 Other chronic obstructive pulmonary disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
1.000 0.000 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
1.000 0.000 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
E11 Non-insulin-dependent diabetes mellitus
0.999 0.001 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.999 0.001 0.000
E11.9 Without complications
0.999 0.001 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.998 0.002 0.000
I20 Angina pectoris
0.996 0.004 0.000
R00 Abnormalities of heart beat
0.995 0.005 0.000
R07 Pain in throat and chest
0.995 0.005 0.000
Chapter XX External causes of morbidity and mortality
0.995 0.005 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
E78.0 Pure hypercholesterolaemia
0.993 0.007 0.000
R06 Abnormalities of breathing
0.993 0.007 0.000
I25.2 Old myocardial infarction
0.992 0.008 0.000
J95-J99 Other diseases of the respiratory system
0.992 0.008 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.992 0.008 0.000
I20.9 Angina pectoris, unspecified
0.987 0.013 0.000
R07.4 Chest pain, unspecified
0.986 0.014 0.000
R06.0 Dyspnoea
0.985 0.015 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.983 0.017 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.982 0.018 0.000
J98 Other respiratory disorders
0.978 0.022 0.000
Chapter V Mental and behavioural disorders
0.978 0.022 0.000
R00.2 Palpitations
0.975 0.025 0.000
I71 Aortic aneurysm and dissection
0.967 0.033 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.965 0.035 0.000
H43-H45 Disorders of vitreous body and globe
0.963 0.037 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.962 0.038 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.960 0.040 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.954 0.046 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.952 0.048 0.000
J30-J39 Other diseases of upper respiratory tract
0.952 0.048 0.000
F41 Other anxiety disorders
0.950 0.050 0.000
R00.1 Bradycardia, unspecified
0.950 0.050 0.000
F41.9 Anxiety disorder, unspecified
0.949 0.051 0.000
Chapter VI Diseases of the nervous system
0.947 0.053 0.000
E11.4 With neurological complications
0.947 0.053 0.000
T66-T78 Other and unspecified effects of external causes
0.946 0.054 0.000
H50 Other strabismus
0.941 0.059 0.000
M05-M14 Inflammatory polyarthropathies
0.932 0.068 0.000
M70-M79 Other soft tissue disorders
0.927 0.073 0.000
H30-H36 Disorders of choroid and retina
0.926 0.074 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.924 0.076 0.000
I25.1 Atherosclerotic heart disease
0.918 0.082 0.000
I73 Other peripheral vascular diseases
0.913 0.087 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.912 0.088 0.000
I20.0 Unstable angina
0.910 0.090 0.000
R07.0 Pain in throat
0.908 0.092 0.000
I60-I69 Cerebrovascular diseases
0.906 0.094 0.000
H50.9 Strabismus, unspecified
0.904 0.096 0.000
H52 Disorders of refraction and accommodation
0.903 0.097 0.000
T78 Adverse effects, not elsewhere classified
0.898 0.102 0.000
E65-E68 Obesity and other hyperalimentation
0.896 0.104 0.000
E78.5 Hyperlipidaemia, unspecified
0.895 0.105 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.893 0.107 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.892 0.108 0.000
J09-J18 Influenza and pneumonia
0.892 0.108 0.000
J98.1 Pulmonary collapse
0.886 0.114 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.885 0.115 0.000
I10-I15 Hypertensive diseases
0.883 0.117 0.000
H25-H28 Disorders of lens
0.882 0.118 0.000
J84 Other interstitial pulmonary diseases
0.882 0.118 0.000
H43 Disorders of vitreous body
0.881 0.119 0.000
G90-G99 Other disorders of the nervous system
0.881 0.119 0.000
T93 Sequelae of injuries of lower limb
0.878 0.122 0.000
R07.2 Precordial pain
0.875 0.125 0.000
H44 Disorders of globe
0.874 0.126 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.872 0.128 0.000
S20-S29 Injuries to the thorax
0.869 0.131 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.869 0.131 0.000
M13 Other arthritis
0.868 0.132 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.863 0.137 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.861 0.139 0.000
H40-H42 Glaucoma
0.861 0.139 0.000
H52.1 Myopia
0.856 0.144 0.000
J98.8 Other specified respiratory disorders
0.855 0.145 0.000
R05 Cough
0.854 0.146 0.000
R50-R69 General symptoms and signs
0.851 0.149 0.000
W00-W19 Falls
0.851 0.149 0.000
H33 Retinal detachments and breaks
0.850 0.150 0.000
H26 Other cataract
0.846 0.154 0.000
E11.3 With ophthalmic complications
0.845 0.155 0.000
X60-X84 Intentional self-harm
0.845 0.155 0.000
R01 Cardiac murmurs and other cardiac sounds
0.843 0.157 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.840 0.160 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.837 0.163 0.000
J37 Chronic laryngitis and laryngotracheitis
0.836 0.164 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.835 0.165 0.000
T92 Sequelae of injuries of upper limb
0.835 0.165 0.000
J98.4 Other disorders of lung
0.835 0.165 0.000
M65-M68 Disorders of synovium and tendon
0.834 0.166 0.000
I73.9 Peripheral vascular disease, unspecified
0.834 0.166 0.000
S70-S79 Injuries to the hip and thigh
0.834 0.166 0.000
E00-E07 Disorders of thyroid gland
0.833 0.167 0.000
F60-F69 Disorders of adult personality and behaviour
0.830 0.169 0.000
S50-S59 Injuries to the elbow and forearm
0.830 0.170 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.829 0.170 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.829 0.171 0.000
I71.9 Aortic aneurysm of unspecified site, without mention of rupture
0.827 0.173 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.827 0.173 0.000
Chapter VIII Diseases of the ear and mastoid process
0.824 0.176 0.000
M91-M94 Chondropathies
0.823 0.177 0.000
I12 Hypertensive renal disease
0.822 0.178 0.000
E66 Obesity
0.821 0.179 0.000
M13.9 Arthritis, unspecified
0.820 0.180 0.000
J80 Adult respiratory distress syndrome
0.820 0.180 0.000
T63 Toxic effect of contact with venomous animals
0.816 0.184 0.000
I78 Diseases of capillaries
0.815 0.185 0.000
H44.2 Degenerative myopia
0.810 0.190 0.000
J39 Other diseases of upper respiratory tract
0.809 0.191 0.000
G30-G32 Other degenerative diseases of the nervous system
0.808 0.192 0.000
M11 Other crystal arthropathies
0.806 0.193 0.000
E50-E64 Other nutritional deficiencies
0.806 0.194 0.000
R06.4 Hyperventilation
0.806 0.194 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.806 0.194 0.000
Chapter I Certain infectious and parasitic diseases
0.804 0.196 0.000
Y52 Agents primarily affecting the cardiovascular system
0.803 0.197 0.000
E88 Other metabolic disorders
0.802 0.198 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.797 0.203 0.000
T79-T79 Certain early complications of trauma
0.794 0.206 0.000
T00-T07 Injuries involving multiple body regions
0.793 0.207 0.000
T78.2 Anaphylactic shock, unspecified
0.793 0.207 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.792 0.208 0.000
J46 Status asthmaticus
0.791 0.209 0.000
H33.0 Retinal detachment with retinal break
0.790 0.210 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.790 0.210 0.000
H26.9 Cataract, unspecified
0.788 0.212 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.788 0.212 0.000
I12.0 Hypertensive renal disease with renal failure
0.787 0.213 0.000
I25.3 Aneurysm of heart
0.786 0.214 0.000
S90-S99 Injuries to the ankle and foot
0.785 0.215 0.000
R06.2 Wheezing
0.782 0.218 0.000
M50-M54 Other dorsopathies
0.781 0.219 0.000
J32 Chronic sinusitis
0.781 0.219 0.000
J43 Emphysema
0.780 0.220 0.000
R58 Haemorrhage, not elsewhere classified
0.779 0.221 0.000
H43.1 Vitreous haemorrhage
0.778 0.222 0.000
H43.8 Other disorders of vitreous body
0.778 0.222 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.777 0.223 0.000
R06.1 Stridor
0.776 0.224 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.775 0.225 0.000
I22 Subsequent myocardial infarction
0.775 0.225 0.000
T91 Sequelae of injuries of neck and trunk
0.774 0.226 0.000
G90 Disorders of autonomic nervous system
0.772 0.228 0.000
R53 Malaise and fatigue
0.771 0.229 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.770 0.230 0.000
J10 Influenza due to identified influenza virus
0.770 0.230 0.000
H31 Other disorders of choroid
0.769 0.231 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.769 0.231 0.000
R68 Other general symptoms and signs
0.769 0.231 0.000
H34 Retinal vascular occlusions
0.768 0.232 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.768 0.232 0.000
E78.1 Pure hyperglyceridaemia
0.768 0.232 0.000
W50-W64 Exposure to animate mechanical forces
0.767 0.233 0.000
E11.0 With coma
0.767 0.233 0.000
R54 Senility
0.766 0.234 0.000
J35 Chronic diseases of tonsils and adenoids
0.765 0.235 0.000
M75 Shoulder lesions
0.765 0.235 0.000
R02 Gangrene, not elsewhere classified
0.765 0.235 0.000
H50.1 Divergent concomitant strabismus
0.763 0.237 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.762 0.237 0.000
E78.2 Mixed hyperlipidaemia
0.762 0.238 0.000
J95.8 Other postprocedural respiratory disorders
0.762 0.238 0.000
T63.4 Venom of other arthropods
0.762 0.238 0.000
H40 Glaucoma
0.762 0.238 0.000
H04 Disorders of lachrymal system
0.761 0.239 0.000
F40 Phobic anxiety disorders
0.760 0.240 0.000
I63 Cerebral infarction
0.759 0.241 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.757 0.243 0.000
I74 Arterial embolism and thrombosis
0.756 0.244 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.756 0.244 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.756 0.244 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.754 0.246 0.000
Y00-Y09 Assault
0.753 0.247 0.000
J37.0 Chronic laryngitis
0.753 0.247 0.000
W20-W49 Exposure to inanimate mechanical forces
0.753 0.247 0.000
I25.4 Coronary artery aneurysm
0.753 0.247 0.000
J98.9 Respiratory disorder, unspecified
0.751 0.249 0.000
T93.8 Sequelae of other specified injuries of lower limb
0.750 0.250 0.000
H55-H59 Other disorders of eye and adnexa
0.750 0.250 0.000
M54 Dorsalgia
0.750 0.250 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.750 0.250 0.000
I62 Other nontraumatic intracranial haemorrhage
0.750 0.250 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.750 0.250 0.000
J30 Vasomotor and allergic rhinitis
0.750 0.250 0.000
I25.5 Ischaemic cardiomyopathy
0.750 0.250 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.749 0.251 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.748 0.252 0.000
J98.6 Disorders of diaphragm
0.748 0.252 0.000
X20-X29 Contact with venomous animals and plants
0.747 0.252 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.747 0.253 0.000
G93 Other disorders of brain
0.746 0.254 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.745 0.255 0.000
E66.8 Other obesity
0.745 0.255 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.744 0.256 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.744 0.256 0.000
B25-B34 Other viral diseases
0.744 0.256 0.000
M77 Other enthesopathies
0.743 0.256 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.743 0.257 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.741 0.259 0.000
H02 Other disorders of eyelid
0.741 0.259 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.740 0.260 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.740 0.260 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.740 0.260 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.739 0.261 0.000
R06.6 Hiccough
0.739 0.261 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.738 0.262 0.000
H26.1 Traumatic cataract
0.738 0.262 0.000
R55 Syncope and collapse
0.737 0.263 0.000
I20.1 Angina pectoris with documented spasm
0.736 0.264 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.736 0.264 0.000
E40-E46 Malnutrition
0.736 0.264 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.736 0.264 0.000
V20-V29 Motorcycle rider injured in transport accident
0.733 0.267 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.733 0.267 0.000
T75 Effects of other external causes
0.733 0.267 0.000
H90-H95 Other disorders of ear
0.731 0.269 0.000
Y85 Sequelae of transport accidents
0.730 0.270 0.000
G70-G73 Diseases of myoneural junction and muscle
0.730 0.270 0.000
F80-F89 Disorders of psychological development
0.729 0.270 0.000
T82.1 Mechanical complication of cardiac electronic device
0.728 0.272 0.000
I73.0 Raynaud's syndrome
0.727 0.273 0.000
V80-V89 Other land transport accidents
0.727 0.273 0.000
H40.1 Primary open-angle glaucoma
0.727 0.273 0.000
G40-G47 Episodic and paroxysmal disorders
0.727 0.273 0.000
T78.4 Allergy, unspecified
0.726 0.274 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.726 0.274 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.726 0.274 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.726 0.274 0.000
Y86 Sequelae of other accidents
0.725 0.275 0.000
F60 Specific personality disorders
0.725 0.275 0.000
R06.8 Other and unspecified abnormalities of breathing
0.724 0.275 0.000
H33.5 Other retinal detachments
0.724 0.276 0.000
I70 Atherosclerosis
0.724 0.276 0.000
I24 Other acute ischaemic heart diseases
0.724 0.276 0.000
M93 Other osteochondropathies
0.723 0.277 0.000
T93.5 Sequelae of injury of muscle and tendon of lower limb
0.722 0.278 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.722 0.278 0.000
M54.9 Dorsalgia, unspecified
0.721 0.279 0.000
V40-V49 Car occupant injured in transport accident
0.721 0.279 0.000
W07 Fall involving chair
0.721 0.279 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.720 0.280 0.000
T17 Foreign body in respiratory tract
0.720 0.280 0.000
H02.1 Ectropion of eyelid
0.720 0.280 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.718 0.282 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.718 0.282 0.000
S10-S19 Injuries to the neck
0.718 0.282 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
E11.8 With unspecified complications
0.717 0.283 0.000
E11.7 With multiple complications
0.717 0.283 0.000
E11.1 With ketoacidosis
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.717 0.283 0.000
M11.2 Other chondrocalcinosis
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.715 0.285 0.000
M06 Other rheumatoid arthritis
0.715 0.285 0.000
M86-M90 Other osteopathies
0.715 0.285 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.715 0.285 0.000
T93.2 Sequelae of other fractures of lower limb
0.713 0.287 0.000
Y35-Y36 Legal intervention and operations of war
0.713 0.287 0.000
Y10-Y34 Event of undetermined intent
0.713 0.287 0.000
X85-X99 Assault
0.713 0.287 0.000
X50-X57 Overexertion, travel and privation
0.713 0.287 0.000
X30-X39 Exposure to forces of nature
0.713 0.287 0.000
X10-X19 Contact with heat and hot substances
0.713 0.287 0.000
X00-X09 Exposure to smoke, fire and flames
0.713 0.287 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.713 0.287 0.000
W75-W84 Other accidental threats to breathing
0.713 0.287 0.000
W65-W74 Accidental drowning and submersion
0.713 0.287 0.000
V98-V99 Other and unspecified transport accidents
0.713 0.287 0.000
V95-V97 Air and space transport accidents
0.713 0.287 0.000
V90-V94 Water transport accidents
0.713 0.287 0.000
V70-V79 Bus occupant injured in transport accident
0.713 0.287 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.713 0.287 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.713 0.287 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.713 0.287 0.000
V01-V09 Pedestrian injured in transport accident
0.713 0.287 0.000
E78.8 Other disorders of lipoprotein metabolism
0.713 0.287 0.000
E78.6 Lipoprotein deficiency
0.713 0.287 0.000
E78.4 Other hyperlipidaemia
0.713 0.287 0.000
E78.3 Hyperchylomicronaemia
0.713 0.287 0.000
E85 Amyloidosis
0.712 0.287 0.000
E84 Cystic fibrosis
0.712 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.287 0.000
E74 Other disorders of carbohydrate metabolism
0.712 0.287 0.000
E73 Lactose intolerance
0.712 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.287 0.000
M60-M63 Disorders of muscles
0.712 0.288 0.000
R06.7 Sneezing
0.712 0.288 0.000
R06.3 Periodic breathing
0.712 0.288 0.000
J96 Respiratory failure, not elsewhere classified
0.711 0.289 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.711 0.289 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.711 0.289 0.000
S27 Injury of other and unspecified intrathoracic organs
0.711 0.289 0.000
S80-S89 Injuries to the knee and lower leg
0.711 0.289 0.000
I72 Other aneurysm
0.710 0.290 0.000
R68.8 Other specified general symptoms and signs
0.710 0.290 0.000
J81 Pulmonary oedema
0.709 0.291 0.000
M75.4 Impingement syndrome of shoulder
0.708 0.292 0.000
E66.0 Obesity due to excess calories
0.707 0.293 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.293 0.000
E04 Other non-toxic goitre
0.706 0.294 0.000
E07 Other disorders of thyroid
0.706 0.294 0.000
E11.5 With peripheral circulatory complications
0.705 0.294 0.000
H52.7 Disorder of refraction, unspecified
0.705 0.295 0.000
H51 Other disorders of binocular movement
0.704 0.296 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.703 0.297 0.000
I67 Other cerebrovascular diseases
0.702 0.298 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.701 0.298 0.000
J98.3 Compensatory emphysema
0.701 0.298 0.000
J98.2 Interstitial emphysema
0.701 0.298 0.000
B34 Viral infection of unspecified site
0.701 0.298 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.701 0.299 0.000
F70-F79 Mental retardation
0.701 0.299 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.701 0.299 0.000
M20-M25 Other joint disorders
0.700 0.300 0.000
J84.8 Other specified interstitial pulmonary diseases
0.699 0.301 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.699 0.301 0.000
E14 Unspecified diabetes mellitus
0.699 0.301 0.000
M10 Gout
0.699 0.301 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.699 0.301 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.698 0.301 0.000
Chapter XI Diseases of the digestive system
0.698 0.302 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.697 0.303 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.697 0.303 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.695 0.305 0.000
E13 Other specified diabetes mellitus
0.694 0.306 0.000
R01.1 Cardiac murmur, unspecified
0.694 0.306 0.000
H49 Paralytic strabismus
0.694 0.306 0.000
I71.8 Aortic aneurysm of unspecified site, ruptured
0.694 0.306 0.000
I71.6 Thoracoabdominal aortic aneurysm, without mention of rupture
0.694 0.306 0.000
I71.5 Thoracoabdominal aortic aneurysm, ruptured
0.694 0.306 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.694 0.306 0.000
I71.1 Thoracic aortic aneurysm, ruptured
0.694 0.306 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.694 0.306 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.693 0.307 0.000
I62.9 Intracranial haemorrhage (nontraumatic), unspecified
0.693 0.307 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.693 0.307 0.000
T95 Sequelae of burns, corrosions and frostbite
0.692 0.308 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.692 0.308 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.692 0.308 0.000
J32.9 Chronic sinusitis, unspecified
0.692 0.308 0.000
I74.5 Embolism and thrombosis of iliac artery
0.692 0.308 0.000
Y89 Sequelae of other external causes
0.691 0.309 0.000
H45 Disorders of vitreous body and globe in diseases classified elsewhere
0.690 0.310 0.000
F48 Other neurotic disorders
0.688 0.311 0.000
F44 Dissociative [conversion] disorders
0.688 0.311 0.000
F42 Obsessive-compulsive disorder
0.688 0.311 0.000
G90.2 Horner's syndrome
0.688 0.312 0.000
I78.1 Naevus, nonneoplastic
0.688 0.312 0.000
M25 Other joint disorders, not elsewhere classified
0.688 0.312 0.000
M65 Synovitis and tenosynovitis
0.687 0.313 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.687 0.313 0.000
G91 Hydrocephalus
0.687 0.313 0.000
Chapter XXII Codes for special purposes
0.687 0.313 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.686 0.314 0.000
K70-K77 Diseases of liver
0.686 0.314 0.000
M00-M03 Infectious arthropathies
0.686 0.314 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.314 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.685 0.315 0.000
T90 Sequelae of injuries of head
0.685 0.315 0.000
T78.3 Angioneurotic oedema
0.684 0.316 0.000
Y84.2 Radiological procedure and radiotherapy
0.683 0.317 0.000
I61 Intracerebral haemorrhage
0.682 0.318 0.000
J35.0 Chronic tonsillitis
0.682 0.318 0.000
W01 Fall on same level from slipping, tripping and stumbling
0.681 0.318 0.000
F41.8 Other specified anxiety disorders
0.681 0.319 0.000
F41.3 Other mixed anxiety disorders
0.681 0.319 0.000
J39.2 Other diseases of pharynx
0.681 0.319 0.000
T92.8 Sequelae of other specified injuries of upper limb
0.681 0.319 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.680 0.320 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.680 0.320 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.680 0.320 0.000
E11.2 With renal complications
0.680 0.320 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.679 0.321 0.000
T74 Maltreatment syndromes
0.678 0.322 0.000
T73 Effects of other deprivation
0.678 0.322 0.000
T70 Effects of air pressure and water pressure
0.678 0.322 0.000
T69 Other effects of reduced temperature
0.678 0.322 0.000
T67 Effects of heat and light
0.678 0.322 0.000
T71 Asphyxiation
0.678 0.322 0.000
T66 Unspecified effects of radiation
0.678 0.322 0.000
T98 Sequelae of other and unspecified effects of external causes
0.677 0.323 0.000
H10-H13 Disorders of conjunctiva
0.675 0.325 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.675 0.325 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.675 0.325 0.000
H50.8 Other specified strabismus
0.674 0.325 0.000
H50.6 Mechanical strabismus
0.674 0.325 0.000
H50.5 Heterophoria
0.674 0.325 0.000
H50.4 Other and unspecified heterotropia
0.674 0.325 0.000
H50.3 Intermittent heterotropia
0.674 0.325 0.000
H50.2 Vertical strabismus
0.674 0.325 0.000
H36 Retinal disorders in diseases classified elsewhere
0.675 0.325 0.000
K70 Alcoholic liver disease
0.673 0.327 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.672 0.328 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.672 0.328 0.000
M25.5 Pain in joint
0.672 0.328 0.000
T68 Hypothermia
0.671 0.329 0.000
B34.9 Viral infection, unspecified
0.671 0.329 0.000
S40-S49 Injuries to the shoulder and upper arm
0.671 0.329 0.000
J43.2 Centrilobular emphysema
0.670 0.330 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.670 0.330 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.670 0.330 0.000
T92.0 Sequelae of open wound of upper limb
0.670 0.330 0.000
S51 Open wound of forearm
0.669 0.331 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.669 0.331 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.668 0.331 0.000
M14 Arthropathies in other diseases classified elsewhere
0.668 0.332 0.000
M12 Other specific arthropathies
0.668 0.332 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.668 0.332 0.000
M08 Juvenile arthritis
0.668 0.332 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.668 0.332 0.000
R09.0 Asphyxia
0.668 0.332 0.000
J30.1 Allergic rhinitis due to pollen
0.668 0.332 0.000
G30 Alzheimer's disease
0.668 0.332 0.000
E11.6 With other specified complications
0.667 0.333 0.000
R61 Hyperhidrosis
0.667 0.333 0.000
J45 Asthma
0.667 0.333 0.000
G93.3 Postviral fatigue syndrome
0.666 0.334 0.000
F99-F99 Unspecified mental disorder
0.666 0.334 0.000
M76 Enthesopathies of lower limb, excluding foot
0.666 0.334 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.665 0.335 0.000
E88.0 Disorders of plasma-protein metabolism, not elsewhere classified
0.665 0.335 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.665 0.335 0.000
I69 Sequelae of cerebrovascular disease
0.665 0.335 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
B15-B19 Viral hepatitis
0.664 0.336 0.000
M79.1 Myalgia
0.664 0.336 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.664 0.336 0.000
H30 Chorioretinal inflammation
0.664 0.336 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.663 0.337 0.000
M79.7 Fibromyalgia
0.663 0.337 0.000
R01.0 Benign and innocent cardiac murmurs
0.662 0.337 0.000
M67 Other disorders of synovium and tendon
0.662 0.338 0.000
H60-H62 Diseases of external ear
0.662 0.338 0.000
S72 Fracture of femur
0.662 0.338 0.000
Y84.0 Cardiac catheterisation
0.661 0.339 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.661 0.339 0.000
M79.5 Residual foreign body in soft tissue
0.661 0.339 0.000
J36 Peritonsillar abscess
0.660 0.340 0.000
H33.1 Retinoschisis and retinal cysts
0.660 0.340 0.000
J11 Influenza, virus not identified
0.660 0.340 0.000
T39.0 Salicylates
0.659 0.341 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.659 0.341 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.658 0.342 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.657 0.343 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.656 0.344 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.655 0.345 0.000
H04.2 Epiphora
0.655 0.345 0.000
M25.56 Pain in joint (Lower leg)
0.655 0.345 0.000
I73.8 Other specified peripheral vascular diseases
0.654 0.346 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.654 0.346 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.654 0.346 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.654 0.346 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.654 0.346 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.654 0.346 0.000
T36 Poisoning by systemic antibiotics
0.654 0.346 0.000
I20.8 Other forms of angina pectoris
0.653 0.347 0.000
M11.26 Other chondrocalcinosis (Lower leg)
0.652 0.348 0.000
M93.9 Osteochondropathy, unspecified
0.652 0.348 0.000
M80-M85 Disorders of bone density and structure
0.651 0.349 0.000
G40 Epilepsy
0.651 0.349 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.650 0.350 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.650 0.350 0.000
S50 Superficial injury of forearm
0.650 0.350 0.000
B00 Herpesviral [herpes simplex] infections
0.650 0.350 0.000
T93.1 Sequelae of fracture of femur
0.649 0.351 0.000
R57 Shock, not elsewhere classified
0.648 0.352 0.000
E61 Deficiency of other nutrient elements
0.647 0.353 0.000
H52.6 Other disorders of refraction
0.647 0.353 0.000
H52.5 Disorders of accommodation
0.647 0.353 0.000
H52.4 Presbyopia
0.647 0.353 0.000
G95 Other diseases of spinal cord
0.647 0.353 0.000
J38.7 Other diseases of larynx
0.647 0.353 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.646 0.354 0.000
M54.1 Radiculopathy
0.646 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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