TreeWAS – Variant ID: rs117784947

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	1.000	0.000
J44 Other chronic obstructive pulmonary disease	1.000	0.000
J40-J47 Chronic lower respiratory diseases	1.000	0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	1.000	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	1.000	0.000
Chapter X Diseases of the respiratory system	1.000	0.000
J44.9 Chronic obstructive pulmonary disease, unspecified	1.000	0.000
R03 Abnormal blood-pressure reading, without diagnosis	0.998	0.002
E78.0 Pure hypercholesterolaemia	0.998	0.002
E78 Disorders of lipoprotein metabolism and other lipidaemias	0.998	0.002
R07 Pain in throat and chest	0.998	0.002
E70-E90 Metabolic disorders	0.998	0.002
Chapter V Mental and behavioural disorders	0.996	0.004
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension	0.996	0.004
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection	0.994	0.006
Chapter IX Diseases of the circulatory system	0.993	0.007
I20-I25 Ischaemic heart diseases	0.991	0.009
I25 Chronic ischaemic heart disease	0.991	0.009
T36-T50 Poisoning by drugs, medicaments and biological substances	0.991	0.009
R06 Abnormalities of breathing	0.986	0.014
E65-E68 Obesity and other hyperalimentation	0.984	0.016
R07.4 Chest pain, unspecified	0.982	0.018
J45 Asthma	0.978	0.022
I10-I15 Hypertensive diseases	0.976	0.024
E66 Obesity	0.973	0.027
R07.2 Precordial pain	0.966	0.034
I10 Essential (primary) hypertension	0.966	0.034
J45.9 Asthma, unspecified	0.963	0.037
Chapter XX External causes of morbidity and mortality	0.958	0.042
F30-F39 Mood [affective] disorders	0.958	0.042
S50-S59 Injuries to the elbow and forearm	0.956	0.044
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.956	0.044
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.952	0.048
E66.9 Obesity, unspecified	0.951	0.049
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.948	0.052
R06.0 Dyspnoea	0.948	0.052
E86 Volume depletion	0.946	0.054
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.946	0.054
I25.9 Chronic ischaemic heart disease, unspecified	0.939	0.061
I25.2 Old myocardial infarction	0.938	0.062
S90-S99 Injuries to the ankle and foot	0.930	0.070
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.928	0.072
I25.8 Other forms of chronic ischaemic heart disease	0.928	0.072
J30-J39 Other diseases of upper respiratory tract	0.928	0.072
R20 Disturbances of skin sensation	0.926	0.074
H50 Other strabismus	0.922	0.078
Chapter VII Diseases of the eye and adnexa	0.920	0.080
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.920	0.080
H50.9 Strabismus, unspecified	0.916	0.084
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.915	0.085
Chapter XXII Codes for special purposes	0.913	0.086
S80-S89 Injuries to the knee and lower leg	0.913	0.087
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.910	0.090
F20 Schizophrenia	0.907	0.093
R07.0 Pain in throat	0.905	0.095
E50-E64 Other nutritional deficiencies	0.904	0.096
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.898	0.102
F33 Recurrent depressive disorder	0.897	0.103
Chapter I Certain infectious and parasitic diseases	0.895	0.105
R23 Other skin changes	0.890	0.110
J46 Status asthmaticus	0.890	0.110
F32 Depressive episode	0.888	0.112
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.886	0.114
F10 Mental and behavioural disorders due to use of alcohol	0.884	0.116
E78.5 Hyperlipidaemia, unspecified	0.883	0.117
J31 Chronic rhinitis, nasopharyngitis and pharyngitis	0.880	0.120
S51 Open wound of forearm	0.880	0.120
T20-T25 Burns and corrosions of external body surface, specified by site	0.877	0.123
F20.9 Schizophrenia, unspecified	0.875	0.125
R20.2 Paraesthesia of skin	0.873	0.127
R06.8 Other and unspecified abnormalities of breathing	0.872	0.128
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.869	0.131
T15-T19 Effects of foreign body entering through natural orifice	0.868	0.132
H50.1 Divergent concomitant strabismus	0.864	0.136
R82 Other abnormal findings in urine	0.863	0.136
Chapter VIII Diseases of the ear and mastoid process	0.863	0.137
R03.1 Nonspecific low blood-pressure reading	0.861	0.139
S60-S69 Injuries to the wrist and hand	0.860	0.140
T39.0 Salicylates	0.854	0.146
E10-E14 Diabetes mellitus	0.854	0.146
J31.0 Chronic rhinitis	0.853	0.147
E66.2 Extreme obesity with alveolar hypoventilation	0.852	0.148
T51 Toxic effect of alcohol	0.852	0.148
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.851	0.149
I70-I79 Diseases of arteries, arterioles and capillaries	0.849	0.151
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.846	0.154
S10-S19 Injuries to the neck	0.845	0.155
S56 Injury of muscle and tendon at forearm level	0.842	0.158
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.842	0.158
E53 Deficiency of other B group vitamins	0.842	0.158
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.839	0.161
I25.1 Atherosclerotic heart disease	0.837	0.163
S70-S79 Injuries to the hip and thigh	0.835	0.165
T51.0 Ethanol	0.828	0.172
F32.9 Depressive episode, unspecified	0.826	0.174
F10.1 Harmful use	0.823	0.177
S83.6 Sprain and strain of other and unspecified parts of knee	0.823	0.177
T93 Sequelae of injuries of lower limb	0.822	0.178
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.818	0.182
R06.6 Hiccough	0.818	0.182
R20.8 Other and unspecified disturbances of skin sensation	0.818	0.182
E11 Non-insulin-dependent diabetes mellitus	0.816	0.184
T79-T79 Certain early complications of trauma	0.815	0.185
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.815	0.185
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.809	0.191
S51.0 Open wound of elbow	0.808	0.192
I71 Aortic aneurysm and dissection	0.805	0.195
R06.1 Stridor	0.800	0.200
H90-H95 Other disorders of ear	0.800	0.200
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.798	0.202
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.798	0.202
E53.8 Deficiency of other specified B group vitamins	0.798	0.202
S69 Other and unspecified injuries of wrist and hand	0.798	0.202
M05-M14 Inflammatory polyarthropathies	0.797	0.203
Y46 Antiepileptics and anti-Parkinsonism drugs	0.796	0.204
S50 Superficial injury of forearm	0.795	0.205
F60-F69 Disorders of adult personality and behaviour	0.795	0.205
X60-X84 Intentional self-harm	0.794	0.206
M13 Other arthritis	0.794	0.206
S81 Open wound of lower leg	0.793	0.207
M13.9 Arthritis, unspecified	0.793	0.207
H50.0 Convergent concomitant strabismus	0.793	0.207
I20 Angina pectoris	0.792	0.208
W50-W64 Exposure to animate mechanical forces	0.792	0.208
F32.2 Severe depressive episode without psychotic symptoms	0.789	0.211
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.787	0.213
J09-J18 Influenza and pneumonia	0.782	0.218
R80 Isolated proteinuria	0.781	0.219
M13.99 Arthritis, unspecified (Site unspecified)	0.781	0.219
R23.2 Flushing	0.781	0.219
J30 Vasomotor and allergic rhinitis	0.781	0.219
R01 Cardiac murmurs and other cardiac sounds	0.780	0.219
E66.0 Obesity due to excess calories	0.780	0.220
S93.1 Dislocation of toe(s)	0.780	0.220
E11.9 Without complications	0.779	0.221
J37 Chronic laryngitis and laryngotracheitis	0.778	0.222
E78.2 Mixed hyperlipidaemia	0.778	0.222
I25.3 Aneurysm of heart	0.777	0.223
I25.4 Coronary artery aneurysm	0.776	0.224
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.776	0.224
R05 Cough	0.775	0.225
F22 Persistent delusional disorders	0.775	0.225
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.775	0.225
S40-S49 Injuries to the shoulder and upper arm	0.774	0.226
I71.4 Abdominal aortic aneurysm, without mention of rupture	0.773	0.227
B35-B49 Mycoses	0.769	0.231
Chapter VI Diseases of the nervous system	0.769	0.231
F10.5 Psychotic disorder	0.768	0.232
H60-H62 Diseases of external ear	0.768	0.232
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms	0.766	0.234
I25.5 Ischaemic cardiomyopathy	0.765	0.235
J39 Other diseases of upper respiratory tract	0.763	0.237
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.763	0.237
I25.0 Atherosclerotic cardiovascular disease, so described	0.761	0.239
S83.5 Sprain and strain involving (anterior)(posterior) cruciate ligament of knee	0.761	0.239
T39.1 4-Aminophenol derivatives	0.761	0.239
F33.9 Recurrent depressive disorder, unspecified	0.760	0.240
W20-W49 Exposure to inanimate mechanical forces	0.760	0.240
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.760	0.240
E80 Disorders of porphyrin and bilirubin metabolism	0.758	0.242
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified	0.754	0.245
S69.9 Unspecified injury of wrist and hand	0.754	0.246
T00-T07 Injuries involving multiple body regions	0.752	0.247
F12 Mental and behavioural disorders due to use of cannabinoids	0.751	0.249
F34 Persistent mood [affective] disorders	0.751	0.249
I20.9 Angina pectoris, unspecified	0.750	0.250
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]	0.749	0.251
T92 Sequelae of injuries of upper limb	0.748	0.252
S51.8 Open wound of other parts of forearm	0.745	0.255
V80-V89 Other land transport accidents	0.744	0.256
E78.1 Pure hyperglyceridaemia	0.744	0.256
S99 Other and unspecified injuries of ankle and foot	0.743	0.256
I71.9 Aortic aneurysm of unspecified site, without mention of rupture	0.744	0.256
S67 Crushing injury of wrist and hand	0.743	0.257
E11.4 With neurological complications	0.743	0.257
R81 Glycosuria	0.742	0.257
Y53 Agents primarily affecting the gastro-intestinal system	0.742	0.258
T17 Foreign body in respiratory tract	0.742	0.258
V20-V29 Motorcycle rider injured in transport accident	0.741	0.259
I21 Acute myocardial infarction	0.740	0.260
R23.1 Pallor	0.740	0.260
S00-S09 Injuries to the head	0.740	0.260
W00-W19 Falls	0.738	0.262
I12 Hypertensive renal disease	0.737	0.263
R82.9 Other and unspecified abnormal finding in urine	0.736	0.264
F99-F99 Unspecified mental disorder	0.735	0.265
H91 Other hearing loss	0.735	0.265
T93.8 Sequelae of other specified injuries of lower limb	0.734	0.266
Y46.4 Iminostilbenes	0.732	0.268
Y51 Drugs primarily affecting the autonomic nervous system	0.731	0.269
T46 Poisoning by agents primarily affecting the cardiovascular system	0.730	0.270
R06.4 Hyperventilation	0.730	0.270
E74 Other disorders of carbohydrate metabolism	0.729	0.270
R82.8 Abnormal findings on cytological and histological examination of urine	0.729	0.271
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.729	0.271
J95-J99 Other diseases of the respiratory system	0.728	0.272
S56.4 Injury of extensor muscle and tendon of other finger(s) at forearm level	0.727	0.273
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.727	0.273
R23.3 Spontaneous ecchymoses	0.727	0.273
M86-M90 Other osteopathies	0.727	0.273
T36 Poisoning by systemic antibiotics	0.726	0.273
X10-X19 Contact with heat and hot substances	0.726	0.273
R06.2 Wheezing	0.726	0.274
T23 Burn and corrosion of wrist and hand	0.723	0.277
T91 Sequelae of injuries of neck and trunk	0.722	0.278
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.721	0.279
R04 Haemorrhage from respiratory passages	0.721	0.279
M65-M68 Disorders of synovium and tendon	0.721	0.279
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.720	0.280
G90-G99 Other disorders of the nervous system	0.720	0.280
I21.9 Acute myocardial infarction, unspecified	0.719	0.281
H60 Otitis externa	0.719	0.281
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
J41 Simple and mucopurulent chronic bronchitis	0.717	0.283
R95-R99 Ill-defined and unknown causes of mortality	0.717	0.283
F25 Schizoaffective disorders	0.717	0.283
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified	0.716	0.284
E78.6 Lipoprotein deficiency	0.715	0.285
E78.4 Other hyperlipidaemia	0.715	0.285
E78.3 Hyperchylomicronaemia	0.715	0.285
E84 Cystic fibrosis	0.715	0.285
E79 Disorders of purine and pyrimidine metabolism	0.715	0.285
E77 Disorders of glycoprotein metabolism	0.715	0.285
E76 Disorders of glycosaminoglycan metabolism	0.715	0.285
E75 Disorders of sphingolipid metabolism and other lipid storage disorders	0.715	0.285
E72 Other disorders of amino-acid metabolism	0.715	0.285
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism	0.715	0.285
E70 Disorders of aromatic amino-acid metabolism	0.715	0.285
E90 Nutritional and metabolic disorders in diseases classified elsewhere	0.715	0.285
Y49 Psychotropic drugs, not elsewhere classified	0.715	0.285
J80-J84 Other respiratory diseases principally affecting the interstitium	0.715	0.285
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.714	0.286
F70-F79 Mental retardation	0.714	0.286
A50-A64 Infections with a predominantly sexual mode of transmission	0.713	0.287
F33.1 Recurrent depressive disorder, current episode moderate	0.713	0.287
S68 Traumatic amputation of wrist and hand	0.712	0.288
I00-I02 Acute rheumatic fever	0.712	0.288
X40-X49 Accidental poisoning by and exposure to noxious substances	0.711	0.289
I23 Certain current complications following acute myocardial infarction	0.711	0.289
I25.6 Silent myocardial ischaemia	0.711	0.289
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.711	0.289
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.711	0.289
T41 Poisoning by anaesthetics and therapeutic gases	0.711	0.289
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.711	0.289
B15-B19 Viral hepatitis	0.710	0.290
H40-H42 Glaucoma	0.709	0.291
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand	0.707	0.292
H43-H45 Disorders of vitreous body and globe	0.707	0.293
S81.0 Open wound of knee	0.707	0.293
R06.7 Sneezing	0.707	0.293
R06.3 Periodic breathing	0.707	0.293
B25-B34 Other viral diseases	0.705	0.295
E67 Other hyperalimentation	0.705	0.295
E68 Sequelae of hyperalimentation	0.705	0.295
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.704	0.296
S91 Open wound of ankle and foot	0.704	0.296
Y00-Y09 Assault	0.703	0.297
T40.2 Other opioids	0.702	0.298
T14 Injury of unspecified body region	0.701	0.299
J45.8 Mixed asthma	0.701	0.299
J45.1 Nonallergic asthma	0.701	0.299
I13 Hypertensive heart and renal disease	0.700	0.300
Y40 Systemic antibiotics	0.699	0.301
I73 Other peripheral vascular diseases	0.699	0.301
R94 Abnormal results of function studies	0.699	0.301
Y95 Nosocomial condition	0.699	0.301
E66.1 Drug-induced obesity	0.698	0.302
F10.9 Unspecified mental and behavioural disorder	0.696	0.304
S12 Fracture of neck	0.696	0.304
F39 Unspecified mood [affective] disorder	0.696	0.304
U89 Agent resistant to other and unspecified antibiotics	0.695	0.305
F33.0 Recurrent depressive disorder, current episode mild	0.693	0.307
B00 Herpesviral [herpes simplex] infections	0.693	0.307
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.692	0.308
M13.96 Arthritis, unspecified (Lower leg)	0.690	0.310
S14 Injury of nerves and spinal cord at neck level	0.690	0.310
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.690	0.310
S86 Injury of muscle and tendon at lower leg level	0.689	0.311
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.688	0.312
Y35-Y36 Legal intervention and operations of war	0.687	0.313
Y10-Y34 Event of undetermined intent	0.687	0.313
X85-X99 Assault	0.687	0.313
X30-X39 Exposure to forces of nature	0.687	0.313
X00-X09 Exposure to smoke, fire and flames	0.687	0.313
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.687	0.313
W75-W84 Other accidental threats to breathing	0.687	0.313
W65-W74 Accidental drowning and submersion	0.687	0.313
V98-V99 Other and unspecified transport accidents	0.687	0.313
V95-V97 Air and space transport accidents	0.687	0.313
V90-V94 Water transport accidents	0.687	0.313
V70-V79 Bus occupant injured in transport accident	0.687	0.313
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.687	0.313
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.687	0.313
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.687	0.313
V01-V09 Pedestrian injured in transport accident	0.687	0.313
R47-R49 Symptoms and signs involving speech and voice	0.687	0.313
F38 Other mood [affective] disorders	0.687	0.313
J15 Bacterial pneumonia, not elsewhere classified	0.686	0.314
E66.8 Other obesity	0.686	0.314
E85 Amyloidosis	0.686	0.314
S59 Other and unspecified injuries of forearm	0.686	0.314
S58 Traumatic amputation of forearm	0.686	0.314
S57 Crushing injury of forearm	0.686	0.314
S55 Injury of blood vessels at forearm level	0.686	0.314
S54 Injury of nerves at forearm level	0.686	0.314
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.686	0.314
S92 Fracture of foot, except ankle	0.685	0.314
J45.0 Predominantly allergic asthma	0.685	0.315
T18 Foreign body in alimentary tract	0.684	0.316
T40.4 Other synthetic narcotics	0.684	0.316
J30.1 Allergic rhinitis due to pollen	0.684	0.316
F10.0 Acute intoxication	0.683	0.317
F28 Other nonorganic psychotic disorders	0.683	0.317
F24 Induced delusional disorder	0.683	0.317
F21 Schizotypal disorder	0.683	0.317
T79 Certain early complications of trauma, not elsewhere classified	0.683	0.317
H91.9 Hearing loss, unspecified	0.682	0.318
T98 Sequelae of other and unspecified effects of external causes	0.682	0.318
Y60-Y69 Misadventures to patients during surgical and medical care	0.682	0.318
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.682	0.318
F30 Manic episode	0.682	0.318
H50.2 Vertical strabismus	0.681	0.319
E88 Other metabolic disorders	0.681	0.319
J38.7 Other diseases of larynx	0.681	0.319
B95-B98 Bacterial, viral and other infectious agents	0.680	0.320
T39.4 Antirheumatics, not elsewhere classified	0.680	0.320
T39.2 Pyrazolone derivatives	0.680	0.320
S64 Injury of nerves at wrist and hand level	0.679	0.321
B20-B24 Human immunodeficiency virus [HIV] disease	0.677	0.323
B35 Dermatophytosis	0.677	0.323
F80-F89 Disorders of psychological development	0.677	0.323
V40-V49 Car occupant injured in transport accident	0.677	0.323
X50-X57 Overexertion, travel and privation	0.676	0.324
E65 Localised adiposity	0.675	0.325
E13 Other specified diabetes mellitus	0.675	0.325
E73 Lactose intolerance	0.673	0.327
F29 Unspecified nonorganic psychosis	0.673	0.327
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.673	0.327
J37.0 Chronic laryngitis	0.671	0.329
I11 Hypertensive heart disease	0.669	0.330
T94 Sequelae of injuries involving multiple and unspecified body regions	0.669	0.331
M65 Synovitis and tenosynovitis	0.669	0.331
E40-E46 Malnutrition	0.668	0.332
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.668	0.332
J40 Bronchitis, not specified as acute or chronic	0.668	0.332
T24 Burn and corrosion of hip and lower limb, except ankle and foot	0.667	0.333
F32.1 Moderate depressive episode	0.667	0.333
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.667	0.333
S98 Traumatic amputation of ankle and foot	0.667	0.333
S97 Crushing injury of ankle and foot	0.667	0.333
S96 Injury of muscle and tendon at ankle and foot level	0.667	0.333
S95 Injury of blood vessels at ankle and foot level	0.667	0.333
S94 Injury of nerves at ankle and foot level	0.667	0.333
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.666	0.334
F18 Mental and behavioural disorders due to use of volatile solvents	0.666	0.334
F16 Mental and behavioural disorders due to use of hallucinogens	0.666	0.334
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.666	0.334
F14 Mental and behavioural disorders due to use of cocaine	0.666	0.334
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.666	0.334
F11 Mental and behavioural disorders due to use of opioids	0.666	0.334
S65 Injury of blood vessels at wrist and hand level	0.665	0.335
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.664	0.336
R20.3 Hyperaesthesia	0.664	0.336
R20.1 Hypoaesthesia of skin	0.664	0.336
R20.0 Anaesthesia of skin	0.664	0.336
X58-X59 Accidental exposure to other and unspecified factors	0.663	0.337
E61 Deficiency of other nutrient elements	0.663	0.337
S90 Superficial injury of ankle and foot	0.662	0.338
H50.8 Other specified strabismus	0.661	0.339
H50.6 Mechanical strabismus	0.661	0.339
H50.5 Heterophoria	0.661	0.339
H50.4 Other and unspecified heterotropia	0.661	0.339
H50.3 Intermittent heterotropia	0.661	0.339
S56.8 Injury of other and unspecified muscles and tendons at forearm level	0.661	0.339
U88 Agent resistant to multiple antibiotics	0.660	0.340
S50.1 Contusion of other and unspecified parts of forearm	0.660	0.340
H51 Other disorders of binocular movement	0.659	0.340
S67.0 Crushing injury of thumb and other finger(s)	0.659	0.341
T58 Toxic effect of carbon monoxide	0.658	0.342
T59 Toxic effect of other gases, fumes and vapours	0.658	0.342
G93 Other disorders of brain	0.658	0.342
R27 Other lack of coordination	0.657	0.343
B99-B99 Other infectious diseases	0.656	0.343
R82.7 Abnormal findings on microbiological examination of urine	0.656	0.343
T95 Sequelae of burns, corrosions and frostbite	0.656	0.344
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.656	0.344
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.656	0.344
S89 Other and unspecified injuries of lower leg	0.655	0.345
S88 Traumatic amputation of lower leg	0.655	0.345
S87 Crushing injury of lower leg	0.655	0.345
S85 Injury of blood vessels at lower leg level	0.655	0.345
S84 Injury of nerves at lower leg level	0.655	0.345
F20.0 Paranoid schizophrenia	0.654	0.346
M13.97 Arthritis, unspecified (Ankle and foot)	0.654	0.346
M13.90 Arthritis, unspecified (Multiple sites)	0.653	0.347
T65 Toxic effect of other and unspecified substances	0.653	0.347
T62 Toxic effect of other noxious substances eaten as food	0.653	0.347
T61 Toxic effect of noxious substances eaten as seafood	0.653	0.347
T60 Toxic effect of pesticides	0.653	0.347
T57 Toxic effect of other inorganic substances	0.653	0.347
T56 Toxic effect of metals	0.653	0.347
T54 Toxic effect of corrosive substances	0.653	0.347
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.653	0.347
T52 Toxic effect of organic solvents	0.653	0.347
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.653	0.347
T55 Toxic effect of soaps and detergents	0.653	0.347
I15 Secondary hypertension	0.651	0.349
H60.9 Otitis externa, unspecified	0.651	0.349
F60 Specific personality disorders	0.650	0.349
F20.8 Other schizophrenia	0.650	0.349
F20.6 Simple schizophrenia	0.650	0.349
F20.5 Residual schizophrenia	0.650	0.349
F20.4 Postschizophrenic depression	0.650	0.349
F20.3 Undifferentiated schizophrenia	0.650	0.349
F20.2 Catatonic schizophrenia	0.650	0.349
F20.1 Hebephrenic schizophrenia	0.650	0.349
F40-F48 Neurotic, stress-related and somatoform disorders	0.650	0.350
J47 Bronchiectasis	0.650	0.350
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.650	0.350
E64 Sequelae of malnutrition and other nutritional deficiencies	0.648	0.352
E63 Other nutritional deficiencies	0.648	0.352
E56 Other vitamin deficiencies	0.648	0.352
E51 Thiamine deficiency	0.648	0.352
E50 Vitamin A deficiency	0.648	0.352
E60 Dietary zinc deficiency	0.648	0.352
E59 Dietary selenium deficiency	0.648	0.352
E58 Dietary calcium deficiency	0.648	0.352
E54 Ascorbic acid deficiency	0.648	0.352
E52 Niacin deficiency [pellagra]	0.648	0.352
F22.0 Delusional disorder	0.648	0.352
A30-A49 Other bacterial diseases	0.648	0.352
H55-H59 Other disorders of eye and adnexa	0.648	0.352
R04.2 Haemoptysis	0.648	0.352
U80 Agent resistant to penicillin and related antibiotics	0.646	0.353
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.646	0.354
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.645	0.355
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants	0.644	0.356
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified	0.644	0.356
T42.5 Mixed antiepileptics, not elsewhere classified	0.644	0.356
T42.3 Barbiturates	0.644	0.356
T42.2 Succinimides and oxazolidinediones	0.644	0.356
T42.1 Iminostilbenes	0.644	0.356
T42.0 Hydantoin derivatives	0.644	0.356
V10-V19 Pedal cyclist injured in transport accident	0.644	0.356
F33.8 Other recurrent depressive disorders	0.643	0.356
F33.4 Recurrent depressive disorder, currently in remission	0.643	0.356
M65.9 Synovitis and tenosynovitis, unspecified	0.642	0.358
B07 Viral warts	0.642	0.358
T45.2 Vitamins, not elsewhere classified	0.642	0.358
B85-B89 Pediculosis, acariasis and other infestations	0.642	0.358
B50-B64 Protozoal diseases	0.642	0.358
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.642	0.358
A75-A79 Rickettsioses	0.642	0.358
A70-A74 Other diseases caused by chlamydiae	0.642	0.358
A65-A69 Other spirochaetal diseases	0.642	0.358
A20-A28 Certain zoonotic bacterial diseases	0.642	0.358
A15-A19 Tuberculosis	0.642	0.358
R23.8 Other and unspecified skin changes	0.640	0.359
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.640	0.359
Y53.1 Other antacids and anti-gastric-secretion drugs	0.640	0.360
J30.3 Other allergic rhinitis	0.640	0.360
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.638	0.361
R23.0 Cyanosis	0.638	0.362
J44.8 Other specified chronic obstructive pulmonary disease	0.638	0.362
S73.0 Dislocation of hip	0.638	0.362
G91 Hydrocephalus	0.637	0.363
X20-X29 Contact with venomous animals and plants	0.637	0.363
S70 Superficial injury of hip and thigh	0.637	0.363
F32.8 Other depressive episodes	0.637	0.363
I70 Atherosclerosis	0.636	0.363
T66-T78 Other and unspecified effects of external causes	0.636	0.364
F23 Acute and transient psychotic disorders	0.636	0.364
J42 Unspecified chronic bronchitis	0.636	0.364
T11 Other injuries of upper limb, level unspecified	0.636	0.364
T17.9 Foreign body in respiratory tract, part unspecified	0.636	0.364
S71 Open wound of hip and thigh	0.635	0.365
Y59 Other and unspecified vaccines and biological substances	0.635	0.365
Y58 Bacterial vaccines	0.635	0.365
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.635	0.365
Y50 Central nervous system stimulants, not elsewhere classified	0.635	0.365
Y48 Anaesthetics and therapeutic gases	0.635	0.365
Y47 Sedatives, hypnotics and antianxiety drugs	0.635	0.365
G30-G32 Other degenerative diseases of the nervous system	0.635	0.365
S02 Fracture of skull and facial bones	0.635	0.365
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms	0.634	0.366
F10.8 Other mental and behavioural disorders	0.634	0.366
F10.7 Residual and late-onset psychotic disorder	0.634	0.366
F10.6 Amnesic syndrome	0.634	0.366
H49 Paralytic strabismus	0.633	0.367
G70-G73 Diseases of myoneural junction and muscle	0.633	0.367
R07.1 Chest pain on breathing	0.633	0.367
M11 Other crystal arthropathies	0.632	0.368
M13.95 Arthritis, unspecified (Pelvic region and thigh)	0.632	0.368
J31.1 Chronic nasopharyngitis	0.631	0.369
S51.7 Multiple open wounds of forearm	0.631	0.369
J39.8 Other specified diseases of upper respiratory tract	0.630	0.369

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations