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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117843447
log Bayes Factor = 14.1413
Chromosome 17   position 20,921,845  (GRCh37) Explore rs117843447 on Ensembl!
Variant rs117843447 is part of Cluster X0191

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
H25-H28 Disorders of lens
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
H25 Senile cataract
0.998 0.002 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.996 0.004 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.996 0.004 0.000
M75 Shoulder lesions
0.995 0.005 0.000
H25.1 Senile nuclear cataract
0.994 0.006 0.000
K86 Other diseases of pancreas
0.993 0.007 0.000
K80 Cholelithiasis
0.991 0.009 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.990 0.010 0.000
Chapter XI Diseases of the digestive system
0.988 0.012 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.984 0.016 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.983 0.017 0.000
K80.0 Calculus of gallbladder with acute cholecystitis
0.980 0.020 0.000
Chapter VI Diseases of the nervous system
0.979 0.021 0.000
S90-S99 Injuries to the ankle and foot
0.975 0.025 0.000
M79.6 Pain in limb
0.970 0.030 0.000
I22 Subsequent myocardial infarction
0.969 0.031 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.969 0.031 0.000
H25.8 Other senile cataract
0.968 0.032 0.000
G40-G47 Episodic and paroxysmal disorders
0.968 0.032 0.000
H53-H54 Visual disturbances and blindness
0.968 0.032 0.000
K86.1 Other chronic pancreatitis
0.963 0.037 0.000
M75.5 Bursitis of shoulder
0.955 0.045 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.954 0.046 0.000
M79.8 Other specified soft tissue disorders
0.954 0.046 0.000
M79.66 Pain in limb (Lower leg)
0.952 0.048 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.951 0.049 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.950 0.050 0.000
M75.4 Impingement syndrome of shoulder
0.950 0.050 0.000
I25.2 Old myocardial infarction
0.949 0.051 0.000
M05-M14 Inflammatory polyarthropathies
0.947 0.053 0.000
M50-M54 Other dorsopathies
0.946 0.054 0.000
Chapter XX External causes of morbidity and mortality
0.946 0.054 0.000
O00-O08 Pregnancy with abortive outcome
0.944 0.056 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.943 0.057 0.000
M75.1 Rotator cuff syndrome
0.940 0.060 0.000
M79.60 Pain in limb (Multiple sites)
0.938 0.062 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.934 0.066 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.934 0.066 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.930 0.070 0.000
M54 Dorsalgia
0.927 0.073 0.000
G44 Other headache syndromes
0.926 0.074 0.000
K35-K38 Diseases of appendix
0.925 0.075 0.000
S60-S69 Injuries to the wrist and hand
0.924 0.076 0.000
H53 Visual disturbances
0.919 0.081 0.000
M13 Other arthritis
0.919 0.081 0.000
M45-M49 Spondylopathies
0.918 0.082 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.913 0.087 0.000
H50 Other strabismus
0.912 0.088 0.000
K80.1 Calculus of gallbladder with other cholecystitis
0.908 0.092 0.000
T43.2 Other and unspecified antidepressants
0.905 0.095 0.000
G43 Migraine
0.903 0.097 0.000
S90 Superficial injury of ankle and foot
0.901 0.099 0.000
K86.0 Alcohol-induced chronic pancreatitis
0.899 0.101 0.000
M13.9 Arthritis, unspecified
0.899 0.101 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.896 0.104 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.893 0.107 0.000
H53.0 Amblyopia ex anopsia
0.890 0.110 0.000
K37 Unspecified appendicitis
0.890 0.110 0.000
O02 Other abnormal products of conception
0.889 0.111 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.889 0.111 0.000
I87 Other disorders of veins
0.885 0.115 0.000
G44.2 Tension-type headache
0.883 0.117 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.880 0.120 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.879 0.121 0.000
T39.1 4-Aminophenol derivatives
0.875 0.125 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.871 0.129 0.000
K80.8 Other cholelithiasis
0.865 0.135 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.865 0.135 0.000
O14 Gestational [pregnancy-induced] hypertension with significant proteinuria
0.864 0.136 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.859 0.141 0.000
M47 Spondylosis
0.859 0.141 0.000
S40-S49 Injuries to the shoulder and upper arm
0.857 0.143 0.000
K85 Acute pancreatitis
0.854 0.146 0.000
K81 Cholecystitis
0.853 0.147 0.000
K86.8 Other specified diseases of pancreas
0.853 0.147 0.000
K86.2 Cyst of pancreas
0.847 0.153 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.847 0.153 0.000
I81 Portal vein thrombosis
0.846 0.154 0.000
I25.5 Ischaemic cardiomyopathy
0.845 0.155 0.000
S50-S59 Injuries to the elbow and forearm
0.841 0.159 0.000
O02.1 Missed abortion
0.841 0.159 0.000
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria
0.841 0.159 0.000
H54 Blindness and low vision
0.840 0.160 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.836 0.164 0.000
S80-S89 Injuries to the knee and lower leg
0.836 0.164 0.000
M54.5 Low back pain
0.835 0.165 0.000
I87.8 Other specified disorders of veins
0.833 0.167 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.832 0.168 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.832 0.168 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.829 0.171 0.000
M79.87 Other specified soft tissue disorders (Ankle and foot)
0.828 0.172 0.000
H27 Other disorders of lens
0.826 0.174 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.824 0.176 0.000
M75.2 Bicipital tendinitis
0.824 0.176 0.000
O42 Premature rupture of membranes
0.824 0.176 0.000
Chapter V Mental and behavioural disorders
0.822 0.178 0.000
M65-M68 Disorders of synovium and tendon
0.821 0.179 0.000
M54.6 Pain in thoracic spine
0.816 0.184 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.816 0.184 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.815 0.184 0.000
K81.9 Cholecystitis, unspecified
0.815 0.185 0.000
K70-K77 Diseases of liver
0.815 0.185 0.000
H50.1 Divergent concomitant strabismus
0.815 0.185 0.000
S40 Superficial injury of shoulder and upper arm
0.814 0.186 0.000
H25.9 Senile cataract, unspecified
0.813 0.187 0.000
H49 Paralytic strabismus
0.812 0.188 0.000
G43.9 Migraine, unspecified
0.812 0.188 0.000
T92 Sequelae of injuries of upper limb
0.811 0.189 0.000
K86.3 Pseudocyst of pancreas
0.811 0.189 0.000
S90.9 Superficial injury of ankle and foot, unspecified
0.810 0.190 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.809 0.191 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.806 0.194 0.000
M10 Gout
0.806 0.194 0.000
M86-M90 Other osteopathies
0.804 0.196 0.000
S92 Fracture of foot, except ankle
0.803 0.197 0.000
M79.62 Pain in limb (Upper arm)
0.800 0.200 0.000
M47.9 Spondylosis, unspecified
0.800 0.200 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.799 0.201 0.000
M13.98 Arthritis, unspecified (Other)
0.794 0.206 0.000
T93 Sequelae of injuries of lower limb
0.794 0.206 0.000
M79.84 Other specified soft tissue disorders (Hand)
0.792 0.208 0.000
G47 Sleep disorders
0.792 0.208 0.000
G70-G73 Diseases of myoneural junction and muscle
0.792 0.208 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.792 0.208 0.000
M54.3 Sciatica
0.791 0.209 0.000
S91 Open wound of ankle and foot
0.791 0.209 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.789 0.211 0.000
Y52 Agents primarily affecting the cardiovascular system
0.789 0.211 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.789 0.211 0.000
W50-W64 Exposure to animate mechanical forces
0.788 0.212 0.000
G90-G99 Other disorders of the nervous system
0.783 0.217 0.000
X60-X84 Intentional self-harm
0.782 0.218 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.781 0.219 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.779 0.221 0.000
M60-M63 Disorders of muscles
0.778 0.222 0.000
H52 Disorders of refraction and accommodation
0.777 0.222 0.000
I85 Oesophageal varices
0.776 0.224 0.000
O03 Spontaneous abortion
0.776 0.224 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.775 0.225 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.775 0.225 0.000
H50.5 Heterophoria
0.775 0.225 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.772 0.228 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.771 0.229 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.769 0.231 0.000
T40.2 Other opioids
0.768 0.232 0.000
G44.8 Other specified headache syndromes
0.766 0.234 0.000
H10-H13 Disorders of conjunctiva
0.764 0.235 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.764 0.236 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.763 0.237 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.762 0.238 0.000
G40 Epilepsy
0.761 0.239 0.000
H50.0 Convergent concomitant strabismus
0.761 0.239 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.759 0.241 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.758 0.242 0.000
M54.4 Lumbago with sciatica
0.758 0.242 0.000
O85-O92 Complications predominantly related to the puerperium
0.756 0.244 0.000
O12 Gestational [pregnancy-induced] oedema and proteinuria without hypertension
0.756 0.244 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.755 0.245 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.755 0.245 0.000
D80-D89 Certain disorders involving the immune mechanism
0.754 0.246 0.000
S62 Fracture at wrist and hand level
0.754 0.246 0.000
S90.8 Other superficial injuries of ankle and foot
0.752 0.248 0.000
O14.0 Moderate preeclampsia
0.751 0.249 0.000
M40-M43 Deforming dorsopathies
0.750 0.250 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.749 0.251 0.000
E10-E14 Diabetes mellitus
0.748 0.252 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.746 0.254 0.000
T90 Sequelae of injuries of head
0.745 0.255 0.000
G43.1 Migraine with aura [classical migraine]
0.744 0.256 0.000
S10-S19 Injuries to the neck
0.740 0.259 0.000
H20 Iridocyclitis
0.740 0.260 0.000
H53.4 Visual field defects
0.739 0.261 0.000
M54.2 Cervicalgia
0.739 0.261 0.000
S60 Superficial injury of wrist and hand
0.738 0.262 0.000
I25.4 Coronary artery aneurysm
0.737 0.263 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.737 0.263 0.000
H54.9 Unspecified visual impairment (binocular)
0.737 0.263 0.000
S20-S29 Injuries to the thorax
0.736 0.264 0.000
V40-V49 Car occupant injured in transport accident
0.736 0.264 0.000
K85.9 Acute pancreatitis, unspecified
0.730 0.270 0.000
S68 Traumatic amputation of wrist and hand
0.730 0.270 0.000
O33 Maternal care for known or suspected disproportion
0.729 0.271 0.000
M91-M94 Chondropathies
0.726 0.274 0.000
G59.0 Diabetic mononeuropathy
0.725 0.275 0.000
M05 Seropositive rheumatoid arthritis
0.725 0.275 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.724 0.276 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.723 0.277 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.722 0.278 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.722 0.278 0.000
I87.1 Compression of vein
0.722 0.278 0.000
M79.5 Residual foreign body in soft tissue
0.720 0.280 0.000
M79.83 Other specified soft tissue disorders (Forearm)
0.720 0.280 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.719 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.719 0.281 0.000
K38 Other diseases of appendix
0.718 0.282 0.000
T92.9 Sequelae of unspecified injury of upper limb
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.716 0.284 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.716 0.284 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
H25.2 Senile cataract, morgagnian type
0.716 0.284 0.000
M76 Enthesopathies of lower limb, excluding foot
0.715 0.285 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.714 0.286 0.000
D86 Sarcoidosis
0.714 0.286 0.000
M75.8 Other shoulder lesions
0.714 0.286 0.000
M75.9 Shoulder lesion, unspecified
0.714 0.286 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.713 0.287 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.713 0.287 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.713 0.287 0.000
G47.3 Sleep apnoea
0.713 0.287 0.000
H53.9 Visual disturbance, unspecified
0.713 0.287 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.713 0.287 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.711 0.289 0.000
K80.3 Calculus of bile duct with cholangitis
0.710 0.290 0.000
M79.9 Soft tissue disorder, unspecified
0.710 0.290 0.000
M79.3 Panniculitis, unspecified
0.710 0.290 0.000
M79.2 Neuralgia and neuritis, unspecified
0.710 0.290 0.000
S81 Open wound of lower leg
0.709 0.291 0.000
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level
0.708 0.292 0.000
M79.82 Other specified soft tissue disorders (Upper arm)
0.708 0.292 0.000
G51 Facial nerve disorders
0.707 0.293 0.000
S70-S79 Injuries to the hip and thigh
0.706 0.294 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.705 0.295 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.705 0.295 0.000
T43.9 Psychotropic drug, unspecified
0.705 0.295 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.705 0.295 0.000
T43.6 Psychostimulants with abuse potential
0.705 0.295 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.705 0.295 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
M10.9 Gout, unspecified
0.705 0.295 0.000
O41 Other disorders of amniotic fluid and membranes
0.705 0.295 0.000
S52 Fracture of forearm
0.704 0.296 0.000
S93.1 Dislocation of toe(s)
0.701 0.299 0.000
Y45.8 Other analgesics and antipyretics
0.701 0.299 0.000
Y48 Anaesthetics and therapeutic gases
0.700 0.300 0.000
M47.1 Other spondylosis with myelopathy
0.700 0.300 0.000
O43 Placental disorders
0.700 0.300 0.000
O14.9 Preeclampsia, unspecified
0.700 0.300 0.000
T79-T79 Certain early complications of trauma
0.699 0.301 0.000
K86.9 Disease of pancreas, unspecified
0.699 0.301 0.000
S99 Other and unspecified injuries of ankle and foot
0.699 0.301 0.000
S98 Traumatic amputation of ankle and foot
0.699 0.301 0.000
S97 Crushing injury of ankle and foot
0.699 0.301 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.699 0.301 0.000
S95 Injury of blood vessels at ankle and foot level
0.699 0.301 0.000
S94 Injury of nerves at ankle and foot level
0.699 0.301 0.000
S67 Crushing injury of wrist and hand
0.699 0.301 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.699 0.301 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.698 0.302 0.000
I86 Varicose veins of other sites
0.697 0.303 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.696 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.304 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.696 0.304 0.000
M79.68 Pain in limb (Other)
0.696 0.304 0.000
M79.61 Pain in limb (Shoulder region)
0.696 0.304 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.696 0.304 0.000
Y43 Primarily systemic agents
0.696 0.304 0.000
H16 Keratitis
0.695 0.305 0.000
H51 Other disorders of binocular movement
0.694 0.306 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.694 0.306 0.000
G41 Status epilepticus
0.694 0.306 0.000
X50-X57 Overexertion, travel and privation
0.694 0.306 0.000
O00 Ectopic pregnancy
0.694 0.306 0.000
M48 Other spondylopathies
0.693 0.307 0.000
S40.0 Contusion of shoulder and upper arm
0.691 0.309 0.000
T93.9 Sequelae of unspecified injury of lower limb
0.690 0.310 0.000
M66 Spontaneous rupture of synovium and tendon
0.690 0.310 0.000
G43.8 Other migraine
0.690 0.310 0.000
K36 Other appendicitis
0.689 0.311 0.000
E10 Insulin-dependent diabetes mellitus
0.689 0.311 0.000
O44 Placenta praevia
0.689 0.311 0.000
H27.8 Other specified disorders of lens
0.688 0.312 0.000
T20 Burn and corrosion of head and neck
0.687 0.313 0.000
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level
0.686 0.313 0.000
I25.3 Aneurysm of heart
0.686 0.314 0.000
I70 Atherosclerosis
0.686 0.314 0.000
I82 Other venous embolism and thrombosis
0.685 0.315 0.000
O02.0 Blighted ovum and nonhydatidiform mole
0.684 0.316 0.000
K80.4 Calculus of bile duct with cholecystitis
0.684 0.316 0.000
M54.56 Low back pain (Lumbar region)
0.684 0.316 0.000
M79.88 Other specified soft tissue disorders (Other)
0.684 0.316 0.000
M79.81 Other specified soft tissue disorders (Shoulder region)
0.684 0.316 0.000
K70 Alcoholic liver disease
0.683 0.317 0.000
O15 Eclampsia
0.682 0.318 0.000
O10 Pre-existing hypertension complicating pregnancy, childbirth and the puerperium
0.682 0.318 0.000
O11 Pre-existing hypertensive disorder with superimposed proteinuria
0.682 0.318 0.000
O47 False labour
0.681 0.319 0.000
T23 Burn and corrosion of wrist and hand
0.680 0.320 0.000
I22.8 Subsequent myocardial infarction of other sites
0.680 0.320 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.679 0.321 0.000
M14 Arthropathies in other diseases classified elsewhere
0.679 0.321 0.000
M12 Other specific arthropathies
0.679 0.321 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.679 0.321 0.000
M08 Juvenile arthritis
0.679 0.321 0.000
Y35-Y36 Legal intervention and operations of war
0.678 0.321 0.000
Y10-Y34 Event of undetermined intent
0.678 0.321 0.000
Y00-Y09 Assault
0.678 0.321 0.000
X85-X99 Assault
0.678 0.321 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.678 0.321 0.000
X30-X39 Exposure to forces of nature
0.678 0.321 0.000
X20-X29 Contact with venomous animals and plants
0.678 0.321 0.000
X10-X19 Contact with heat and hot substances
0.678 0.321 0.000
X00-X09 Exposure to smoke, fire and flames
0.678 0.321 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.678 0.321 0.000
W75-W84 Other accidental threats to breathing
0.678 0.321 0.000
W65-W74 Accidental drowning and submersion
0.678 0.321 0.000
V98-V99 Other and unspecified transport accidents
0.678 0.321 0.000
V95-V97 Air and space transport accidents
0.678 0.321 0.000
V90-V94 Water transport accidents
0.678 0.321 0.000
V70-V79 Bus occupant injured in transport accident
0.678 0.321 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.678 0.321 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.678 0.321 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.678 0.321 0.000
V01-V09 Pedestrian injured in transport accident
0.678 0.321 0.000
M53 Other dorsopathies, not elsewhere classified
0.678 0.322 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.677 0.323 0.000
O07 Failed attempted abortion
0.677 0.323 0.000
O06 Unspecified abortion
0.677 0.323 0.000
O05 Other abortion
0.677 0.323 0.000
O01 Hydatidiform mole
0.677 0.323 0.000
O45 Premature separation of placenta [abruptio placentae]
0.676 0.324 0.000
O31 Complications specific to multiple gestation
0.676 0.324 0.000
M65 Synovitis and tenosynovitis
0.676 0.324 0.000
H52.1 Myopia
0.675 0.325 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.674 0.326 0.000
T39.0 Salicylates
0.673 0.327 0.000
H54.4 Blindness, one eye
0.673 0.327 0.000
F30-F39 Mood [affective] disorders
0.672 0.328 0.000
M54.39 Sciatica (Site unspecified)
0.672 0.328 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.672 0.328 0.000
I88 Nonspecific lymphadenitis
0.670 0.330 0.000
Y59 Other and unspecified vaccines and biological substances
0.670 0.330 0.000
Y58 Bacterial vaccines
0.670 0.330 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.670 0.330 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.670 0.330 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.670 0.330 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.670 0.330 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.670 0.330 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.670 0.330 0.000
H49.2 Sixth [abducent] nerve palsy
0.670 0.330 0.000
S80 Superficial injury of lower leg
0.668 0.332 0.000
G54 Nerve root and plexus disorders
0.668 0.332 0.000
O30 Multiple gestation
0.667 0.332 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.667 0.333 0.000
T98 Sequelae of other and unspecified effects of external causes
0.666 0.333 0.000
T95 Sequelae of burns, corrosions and frostbite
0.666 0.333 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.666 0.333 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.666 0.333 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.666 0.333 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.666 0.333 0.000
Y40 Systemic antibiotics
0.666 0.334 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.666 0.334 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.665 0.335 0.000
I10-I15 Hypertensive diseases
0.665 0.335 0.000
M47.2 Other spondylosis with radiculopathy
0.665 0.335 0.000
M54.8 Other dorsalgia
0.665 0.335 0.000
M54.0 Panniculitis affecting regions of neck and back
0.665 0.335 0.000
M13.0 Polyarthritis, unspecified
0.664 0.336 0.000
O14.1 Severe preeclampsia
0.664 0.336 0.000
M71 Other bursopathies
0.664 0.336 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.664 0.336 0.000
G44.3 Chronic posttraumatic headache
0.664 0.336 0.000
G44.1 Vascular headache, not elsewhere classified
0.664 0.336 0.000
K83 Other diseases of biliary tract
0.663 0.337 0.000
S00-S09 Injuries to the head
0.662 0.338 0.000
K76 Other diseases of liver
0.662 0.338 0.000
S65 Injury of blood vessels at wrist and hand level
0.662 0.338 0.000
M89 Other disorders of bone
0.662 0.338 0.000
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level
0.662 0.338 0.000
S86 Injury of muscle and tendon at lower leg level
0.661 0.339 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.661 0.339 0.000
O80-O84 Delivery
0.661 0.339 0.000
H53.6 Night blindness
0.659 0.341 0.000
H53.5 Colour vision deficiencies
0.659 0.341 0.000
H53.3 Other disorders of binocular vision
0.659 0.341 0.000
M13.8 Other specified arthritis
0.659 0.341 0.000
M13.1 Monoarthritis, not elsewhere classified
0.659 0.341 0.000
M49 Spondylopathies in diseases classified elsewhere
0.658 0.342 0.000
I80 Phlebitis and thrombophlebitis
0.658 0.342 0.000
W00-W19 Falls
0.657 0.343 0.000
M46 Other inflammatory spondylopathies
0.657 0.343 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.655 0.345 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.655 0.345 0.000
O32.8 Maternal care for other malpresentation of foetus
0.655 0.345 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.655 0.345 0.000
T39.4 Antirheumatics, not elsewhere classified
0.655 0.345 0.000
T39.2 Pyrazolone derivatives
0.655 0.345 0.000
E11 Non-insulin-dependent diabetes mellitus
0.655 0.345 0.000
K85.1 Biliary acute pancreatitis
0.655 0.345 0.000
H17 Corneal scars and opacities
0.655 0.345 0.000
H21 Other disorders of iris and ciliary body
0.654 0.346 0.000
H50.8 Other specified strabismus
0.654 0.346 0.000
H50.6 Mechanical strabismus
0.654 0.346 0.000
H50.4 Other and unspecified heterotropia
0.654 0.346 0.000
H50.3 Intermittent heterotropia
0.654 0.346 0.000
H50.2 Vertical strabismus
0.654 0.346 0.000
K73 Chronic hepatitis, not elsewhere classified
0.654 0.346 0.000
S69 Other and unspecified injuries of wrist and hand
0.654 0.346 0.000
I71 Aortic aneurysm and dissection
0.654 0.346 0.000
M79.85 Other specified soft tissue disorders (Pelvic region and thigh)
0.654 0.346 0.000
M79.1 Myalgia
0.653 0.347 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.653 0.347 0.000
F80-F89 Disorders of psychological development
0.653 0.347 0.000
S51 Open wound of forearm
0.653 0.347 0.000
T44.3 Other parasympatholytics [anticholinergics and antimuscarines] and spasmolytics, not elsewhere classified
0.652 0.348 0.000
K65-K67 Diseases of peritoneum
0.652 0.348 0.000
S66.9 Injury of unspecified muscle and tendon at wrist and hand level
0.651 0.349 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.651 0.349 0.000
M10.97 Gout, unspecified (Ankle and foot)
0.650 0.350 0.000
S64 Injury of nerves at wrist and hand level
0.649 0.351 0.000
T46.4 Angiotensin-converting-enzyme inhibitors
0.649 0.351 0.000
M54.9 Dorsalgia, unspecified
0.648 0.352 0.000
V80-V89 Other land transport accidents
0.647 0.352 0.000
G43.3 Complicated migraine
0.647 0.353 0.000
G43.2 Status migrainosus
0.647 0.353 0.000
G43.0 Migraine without aura [common migraine]
0.647 0.353 0.000
M80-M85 Disorders of bone density and structure
0.647 0.353 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.646 0.354 0.000
S90.7 Multiple superficial injuries of ankle and foot
0.646 0.354 0.000
S90.3 Contusion of other and unspecified parts of foot
0.646 0.354 0.000
S90.2 Contusion of toe(s) with damage to nail
0.646 0.354 0.000
S90.1 Contusion of toe(s) without damage to nail
0.646 0.354 0.000
S90.0 Contusion of ankle
0.646 0.354 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.645 0.355 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.645 0.355 0.000
H53.2 Diplopia
0.645 0.355 0.000
O34.1 Maternal care for tumour of corpus uteri
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.643 0.357 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.643 0.357 0.000
H53.1 Subjective visual disturbances
0.643 0.357 0.000
M79.7 Fibromyalgia
0.642 0.358 0.000
I85.9 Oesophageal varices without bleeding
0.642 0.358 0.000
I89.0 Lymphoedema, not elsewhere classified
0.641 0.359 0.000
T93.3 Sequelae of dislocation, sprain and strain of lower limb
0.641 0.359 0.000
I74 Arterial embolism and thrombosis
0.641 0.359 0.000
M13.93 Arthritis, unspecified (Forearm)
0.640 0.360 0.000
O32.1 Maternal care for breech presentation
0.640 0.360 0.000
H27.1 Dislocation of lens
0.639 0.360 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.638 0.362 0.000
O02.9 Abnormal product of conception, unspecified
0.638 0.362 0.000
O02.8 Other specified abnormal products of conception
0.638 0.362 0.000
Y45.9 Analgesic, antipyretic and anti-inflammatory drug, unspecified
0.637 0.362 0.000
Y45.5 4-Aminophenol derivatives
0.637 0.362 0.000
Y45.4 Antirheumatics
0.637 0.362 0.000
Y45.2 Propionic acid derivatives
0.637 0.362 0.000
H55-H59 Other disorders of eye and adnexa
0.635 0.364 0.000
S92.3 Fracture of metatarsal bone
0.635 0.365 0.000
Y44 Agents primarily affecting blood constituents
0.634 0.365 0.000
I87.9 Disorder of vein, unspecified
0.634 0.366 0.000
I87.0 Postphlebitic syndrome
0.634 0.366 0.000
M54.50 Low back pain (Multiple sites in spine)
0.634 0.366 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.634 0.366 0.000
O04 Medical abortion
0.634 0.366 0.000
E16 Other disorders of pancreatic internal secretion
0.634 0.366 0.000
O46.9 Antepartum haemorrhage, unspecified
0.632 0.368 0.000
Y57 Other and unspecified drugs and medicaments
0.632 0.368 0.000
E10.4 With neurological complications
0.631 0.369 0.000
H49.0 Third [oculomotor] nerve palsy
0.630 0.369 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.630 0.370 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.630 0.370 0.000
H15 Disorders of sclera
0.630 0.370 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.630 0.370 0.000
T92.0 Sequelae of open wound of upper limb
0.629 0.371 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.628 0.372 0.000
I30-I52 Other forms of heart disease
0.628 0.372 0.000
T92.5 Sequelae of injury of muscle and tendon of upper limb
0.627 0.373 0.000
M11 Other crystal arthropathies
0.627 0.373 0.000
M54.57 Low back pain (Lumbosacral region)
0.627 0.373 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.626 0.374 0.000
G72 Other myopathies
0.626 0.374 0.000
E50-E64 Other nutritional deficiencies
0.625 0.375 0.000
T25 Burn and corrosion of ankle and foot
0.625 0.375 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.625 0.375 0.000
T21 Burn and corrosion of trunk
0.625 0.375 0.000
M45 Ankylosing spondylitis
0.625 0.375 0.000
D86.9 Sarcoidosis, unspecified
0.624 0.376 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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