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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117843550
log Bayes Factor = 13.8383
Chromosome 7   position 144,155,010  (GRCh37) Explore rs117843550 on Ensembl!
Variant rs117843550 is part of Cluster X0044

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
R55 Syncope and collapse
0.996 0.004 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.996 0.004 0.000
Chapter XXI Factors influencing health status and contact with health services
0.995 0.005 0.000
J44 Other chronic obstructive pulmonary disease
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Z85 Personal history of malignant neoplasm
0.993 0.007 0.000
Chapter I Certain infectious and parasitic diseases
0.984 0.016 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.972 0.028 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.971 0.029 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.971 0.029 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.968 0.032 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.955 0.045 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.953 0.047 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.951 0.049 0.000
J45 Asthma
0.950 0.050 0.000
M45-M49 Spondylopathies
0.944 0.056 0.000
J30-J39 Other diseases of upper respiratory tract
0.938 0.062 0.000
Chapter II Neoplasms
0.936 0.064 0.000
A00-A09 Intestinal infectious diseases
0.929 0.071 0.000
M05-M14 Inflammatory polyarthropathies
0.927 0.073 0.000
J90-J94 Other diseases of pleura
0.924 0.076 0.000
Chapter XX External causes of morbidity and mortality
0.921 0.079 0.000
J45.9 Asthma, unspecified
0.921 0.079 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.917 0.083 0.000
J43 Emphysema
0.916 0.084 0.000
G40-G47 Episodic and paroxysmal disorders
0.916 0.084 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.914 0.086 0.000
Z85.6 Personal history of leukaemia
0.913 0.087 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.908 0.092 0.000
S80-S89 Injuries to the knee and lower leg
0.908 0.092 0.000
M13 Other arthritis
0.906 0.094 0.000
Z85.3 Personal history of malignant neoplasm of breast
0.905 0.095 0.000
Chapter VII Diseases of the eye and adnexa
0.903 0.097 0.000
R63 Symptoms and signs concerning food and fluid intake
0.900 0.100 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.894 0.106 0.000
G40 Epilepsy
0.893 0.107 0.000
B35-B49 Mycoses
0.890 0.110 0.000
R51 Headache
0.885 0.115 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.883 0.117 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.881 0.119 0.000
Chapter V Mental and behavioural disorders
0.881 0.119 0.000
Z91.6 Personal history of other physical trauma
0.880 0.120 0.000
G90-G99 Other disorders of the nervous system
0.879 0.121 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.879 0.121 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.878 0.122 0.000
M13.9 Arthritis, unspecified
0.878 0.122 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.877 0.123 0.000
Z82.3 Family history of stroke
0.876 0.124 0.000
J40 Bronchitis, not specified as acute or chronic
0.876 0.124 0.000
J95-J99 Other diseases of the respiratory system
0.875 0.125 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.875 0.125 0.000
M48 Other spondylopathies
0.870 0.130 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.870 0.130 0.000
R57 Shock, not elsewhere classified
0.867 0.133 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.867 0.133 0.000
Z98 Other postsurgical states
0.864 0.136 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.864 0.136 0.000
W00-W19 Falls
0.863 0.137 0.000
Chapter XXII Codes for special purposes
0.863 0.137 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.863 0.137 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.862 0.138 0.000
J90 Pleural effusion, not elsewhere classified
0.860 0.140 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.859 0.141 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.859 0.141 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.857 0.143 0.000
R26 Abnormalities of gait and mobility
0.857 0.143 0.000
J43.9 Emphysema, unspecified
0.856 0.144 0.000
H53-H54 Visual disturbances and blindness
0.856 0.144 0.000
J34 Other disorders of nose and nasal sinuses
0.855 0.145 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.854 0.146 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.853 0.147 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.850 0.150 0.000
J60-J70 Lung diseases due to external agents
0.848 0.152 0.000
G40.9 Epilepsy, unspecified
0.847 0.153 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.846 0.154 0.000
M45 Ankylosing spondylitis
0.843 0.157 0.000
J47 Bronchiectasis
0.841 0.159 0.000
R54 Senility
0.835 0.165 0.000
J00-J06 Acute upper respiratory infections
0.831 0.169 0.000
M46 Other inflammatory spondylopathies
0.826 0.174 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.824 0.176 0.000
R63.0 Anorexia
0.824 0.176 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.823 0.177 0.000
S50-S59 Injuries to the elbow and forearm
0.822 0.178 0.000
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung
0.820 0.180 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.816 0.184 0.000
T39.1 4-Aminophenol derivatives
0.816 0.184 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.813 0.187 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.811 0.189 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.811 0.189 0.000
S82 Fracture of lower leg, including ankle
0.810 0.190 0.000
Z97 Presence of other devices
0.810 0.190 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.191 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.808 0.192 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.807 0.193 0.000
R47-R49 Symptoms and signs involving speech and voice
0.804 0.196 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.803 0.197 0.000
S70-S79 Injuries to the hip and thigh
0.803 0.197 0.000
B37 Candidiasis
0.803 0.197 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.800 0.200 0.000
S20-S29 Injuries to the thorax
0.796 0.204 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.795 0.205 0.000
M80-M85 Disorders of bone density and structure
0.794 0.205 0.000
Z93 Artificial opening status
0.793 0.207 0.000
G35 Multiple sclerosis
0.792 0.208 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.792 0.208 0.000
Q60-Q64 Congenital malformations of the urinary system
0.783 0.217 0.000
S60-S69 Injuries to the wrist and hand
0.782 0.218 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.782 0.218 0.000
J46 Status asthmaticus
0.780 0.220 0.000
R53 Malaise and fatigue
0.779 0.221 0.000
H54 Blindness and low vision
0.776 0.224 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.774 0.226 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.773 0.227 0.000
A80-A89 Viral infections of the central nervous system
0.773 0.227 0.000
M48.0 Spinal stenosis
0.771 0.229 0.000
R27 Other lack of coordination
0.771 0.229 0.000
M13.0 Polyarthritis, unspecified
0.771 0.229 0.000
T90 Sequelae of injuries of head
0.771 0.229 0.000
C64-C68 Malignant neoplasms of urinary tract
0.768 0.231 0.000
J09-J18 Influenza and pneumonia
0.768 0.232 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.768 0.232 0.000
A08 Viral and other specified intestinal infections
0.768 0.232 0.000
G70-G73 Diseases of myoneural junction and muscle
0.767 0.233 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.766 0.234 0.000
Z89 Acquired absence of limb
0.766 0.234 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.766 0.234 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.764 0.236 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.762 0.238 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.761 0.239 0.000
H55-H59 Other disorders of eye and adnexa
0.761 0.239 0.000
R26.8 Other and unspecified abnormalities of gait and mobility
0.761 0.239 0.000
J38.7 Other diseases of larynx
0.760 0.240 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.760 0.240 0.000
S89 Other and unspecified injuries of lower leg
0.760 0.240 0.000
T42.4 Benzodiazepines
0.757 0.243 0.000
Z94 Transplanted organ and tissue status
0.756 0.244 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.756 0.244 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.756 0.244 0.000
Z98.1 Arthrodesis status
0.756 0.244 0.000
H53 Visual disturbances
0.753 0.247 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.753 0.247 0.000
M70-M79 Other soft tissue disorders
0.752 0.248 0.000
G20-G26 Extrapyramidal and movement disorders
0.752 0.248 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.751 0.249 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.751 0.249 0.000
S10-S19 Injuries to the neck
0.750 0.250 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.746 0.254 0.000
B15-B19 Viral hepatitis
0.746 0.254 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.745 0.255 0.000
R57.0 Cardiogenic shock
0.745 0.255 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.744 0.256 0.000
G62 Other polyneuropathies
0.743 0.257 0.000
T79-T79 Certain early complications of trauma
0.743 0.257 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.743 0.257 0.000
M13.98 Arthritis, unspecified (Other)
0.742 0.258 0.000
M46.9 Inflammatory spondylopathy, unspecified
0.742 0.258 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.741 0.259 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.740 0.260 0.000
F60-F69 Disorders of adult personality and behaviour
0.739 0.261 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.739 0.261 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.738 0.262 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.738 0.262 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.738 0.262 0.000
M91-M94 Chondropathies
0.737 0.263 0.000
M13.94 Arthritis, unspecified (Hand)
0.736 0.264 0.000
J39 Other diseases of upper respiratory tract
0.736 0.264 0.000
G93 Other disorders of brain
0.735 0.265 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.735 0.265 0.000
F99-F99 Unspecified mental disorder
0.733 0.267 0.000
Z96 Presence of other functional implants
0.733 0.267 0.000
R60 Oedema, not elsewhere classified
0.732 0.268 0.000
T92 Sequelae of injuries of upper limb
0.731 0.269 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.730 0.270 0.000
A30-A49 Other bacterial diseases
0.729 0.271 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.729 0.271 0.000
W08 Fall involving other furniture
0.728 0.272 0.000
C34 Malignant neoplasm of bronchus and lung
0.728 0.272 0.000
R76 Other abnormal immunological findings in serum
0.728 0.272 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.728 0.272 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.727 0.272 0.000
M05 Seropositive rheumatoid arthritis
0.726 0.274 0.000
D00-D09 In situ neoplasms
0.725 0.275 0.000
J98 Other respiratory disorders
0.724 0.276 0.000
J34.2 Deviated nasal septum
0.723 0.277 0.000
G47 Sleep disorders
0.722 0.278 0.000
G95 Other diseases of spinal cord
0.721 0.279 0.000
R25 Abnormal involuntary movements
0.718 0.282 0.000
M86-M90 Other osteopathies
0.718 0.282 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
J42 Unspecified chronic bronchitis
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.714 0.286 0.000
Z84 Family history of other conditions
0.714 0.286 0.000
Z81 Family history of mental and behavioural disorders
0.714 0.286 0.000
R68 Other general symptoms and signs
0.713 0.287 0.000
C91 Lymphoid leukaemia
0.713 0.287 0.000
J92 Pleural plaque
0.712 0.288 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.712 0.288 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.712 0.288 0.000
C77.3 Axillary and upper limb lymph nodes
0.712 0.288 0.000
R61 Hyperhidrosis
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.711 0.289 0.000
Z22 Carrier of infectious disease
0.710 0.290 0.000
T39.0 Salicylates
0.709 0.291 0.000
R59 Enlarged lymph nodes
0.709 0.291 0.000
R79 Other abnormal findings of blood chemistry
0.708 0.291 0.000
J38.0 Paralysis of vocal cords and larynx
0.708 0.291 0.000
A09.0 Other and unspecified gastroenteritis and colitis of infectious origin
0.707 0.293 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.706 0.294 0.000
Z90.0 Acquired absence of part of head and neck
0.706 0.294 0.000
B99-B99 Other infectious diseases
0.706 0.294 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.706 0.294 0.000
B65-B83 Helminthiases
0.706 0.294 0.000
B50-B64 Protozoal diseases
0.706 0.294 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.706 0.294 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.706 0.294 0.000
A75-A79 Rickettsioses
0.706 0.294 0.000
A70-A74 Other diseases caused by chlamydiae
0.706 0.294 0.000
A65-A69 Other spirochaetal diseases
0.706 0.294 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.706 0.294 0.000
A20-A28 Certain zoonotic bacterial diseases
0.706 0.294 0.000
A15-A19 Tuberculosis
0.706 0.294 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.705 0.295 0.000
H10-H13 Disorders of conjunctiva
0.705 0.295 0.000
T66-T78 Other and unspecified effects of external causes
0.705 0.295 0.000
F80-F89 Disorders of psychological development
0.703 0.297 0.000
S82.3 Fracture of lower end of tibia
0.703 0.297 0.000
H43-H45 Disorders of vitreous body and globe
0.703 0.297 0.000
B25-B34 Other viral diseases
0.702 0.298 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.702 0.298 0.000
Q61 Cystic kidney disease
0.700 0.300 0.000
W10 Fall on and from stairs and steps
0.699 0.301 0.000
R63.1 Polydipsia
0.698 0.302 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.698 0.302 0.000
V10-V19 Pedal cyclist injured in transport accident
0.698 0.302 0.000
C79 Secondary malignant neoplasm of other sites
0.697 0.303 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.697 0.303 0.000
W07 Fall involving chair
0.697 0.303 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.697 0.303 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.697 0.303 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.697 0.303 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.697 0.303 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.697 0.303 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.697 0.303 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.697 0.303 0.000
T36 Poisoning by systemic antibiotics
0.697 0.303 0.000
M60-M63 Disorders of muscles
0.696 0.303 0.000
M00-M03 Infectious arthropathies
0.696 0.303 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.696 0.304 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.696 0.304 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.696 0.304 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.696 0.304 0.000
Z82.2 Family history of deafness and hearing loss
0.696 0.304 0.000
Z82.1 Family history of blindness and visual loss
0.696 0.304 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.695 0.304 0.000
B35 Dermatophytosis
0.695 0.305 0.000
J34.3 Hypertrophy of nasal turbinates
0.695 0.305 0.000
S40-S49 Injuries to the shoulder and upper arm
0.694 0.306 0.000
V80-V89 Other land transport accidents
0.693 0.306 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.693 0.307 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.691 0.309 0.000
W19 Unspecified fall
0.691 0.309 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.689 0.311 0.000
R29.6 Tendency to fall, not elsewhere classified
0.688 0.312 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.686 0.314 0.000
Z83 Family history of other specific disorders
0.685 0.314 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.684 0.316 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.684 0.316 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.683 0.317 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.683 0.317 0.000
Z91.7 Personal history of female genital mutilation
0.683 0.317 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.683 0.317 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.683 0.317 0.000
Z91.2 Personal history of poor personal hygiene
0.683 0.317 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.682 0.317 0.000
T87 Complications peculiar to reattachment and amputation
0.682 0.318 0.000
T86 Failure and rejection of transplanted organs and tissues
0.682 0.318 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.682 0.318 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.682 0.318 0.000
J45.8 Mixed asthma
0.681 0.319 0.000
J45.1 Nonallergic asthma
0.681 0.319 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.681 0.319 0.000
H54.0 Blindness, both eyes
0.681 0.319 0.000
F30-F39 Mood [affective] disorders
0.679 0.321 0.000
R57.2 Septic shock
0.679 0.321 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.678 0.322 0.000
M40-M43 Deforming dorsopathies
0.678 0.322 0.000
R26.3 Immobility
0.677 0.323 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.677 0.323 0.000
T90.2 Sequelae of fracture of skull and facial bones
0.677 0.323 0.000
J03 Acute tonsillitis
0.677 0.323 0.000
M49 Spondylopathies in diseases classified elsewhere
0.677 0.323 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.676 0.324 0.000
G91 Hydrocephalus
0.676 0.324 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.675 0.325 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.674 0.325 0.000
S82.6 Fracture of lateral malleolus
0.674 0.325 0.000
Y43 Primarily systemic agents
0.674 0.326 0.000
J69 Pneumonitis due to solids and liquids
0.674 0.326 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.674 0.326 0.000
S81 Open wound of lower leg
0.673 0.327 0.000
J37 Chronic laryngitis and laryngotracheitis
0.673 0.327 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.672 0.328 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.672 0.328 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.671 0.329 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.671 0.329 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
Z97.8 Presence of other specified devices
0.670 0.330 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.669 0.331 0.000
Z93.2 Ileostomy status
0.668 0.332 0.000
S92 Fracture of foot, except ankle
0.667 0.333 0.000
A07 Other protozoal intestinal diseases
0.666 0.334 0.000
A06 Amoebiasis
0.666 0.334 0.000
A05 Other bacterial foodborne intoxications
0.666 0.334 0.000
A03 Shigellosis
0.666 0.334 0.000
A02 Other Salmonella infections
0.666 0.334 0.000
A01 Typhoid and paratyphoid fevers
0.666 0.334 0.000
A00 Cholera
0.666 0.334 0.000
S72 Fracture of femur
0.666 0.334 0.000
M14 Arthropathies in other diseases classified elsewhere
0.665 0.335 0.000
M12 Other specific arthropathies
0.665 0.335 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.665 0.335 0.000
M08 Juvenile arthritis
0.665 0.335 0.000
Y57 Other and unspecified drugs and medicaments
0.664 0.336 0.000
J94 Other pleural conditions
0.663 0.337 0.000
J91 Pleural effusion in conditions classified elsewhere
0.663 0.337 0.000
R49 Voice disturbances
0.662 0.337 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.662 0.338 0.000
Z90.1 Acquired absence of breast(s)
0.662 0.338 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.661 0.338 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.661 0.339 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.661 0.339 0.000
Y35-Y36 Legal intervention and operations of war
0.661 0.339 0.000
Y10-Y34 Event of undetermined intent
0.661 0.339 0.000
Y00-Y09 Assault
0.661 0.339 0.000
X85-X99 Assault
0.661 0.339 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.661 0.339 0.000
X50-X57 Overexertion, travel and privation
0.661 0.339 0.000
X30-X39 Exposure to forces of nature
0.661 0.339 0.000
X20-X29 Contact with venomous animals and plants
0.661 0.339 0.000
X10-X19 Contact with heat and hot substances
0.661 0.339 0.000
X00-X09 Exposure to smoke, fire and flames
0.661 0.339 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.661 0.339 0.000
W75-W84 Other accidental threats to breathing
0.661 0.339 0.000
W65-W74 Accidental drowning and submersion
0.661 0.339 0.000
W50-W64 Exposure to animate mechanical forces
0.661 0.339 0.000
V98-V99 Other and unspecified transport accidents
0.661 0.339 0.000
V95-V97 Air and space transport accidents
0.661 0.339 0.000
V90-V94 Water transport accidents
0.661 0.339 0.000
V70-V79 Bus occupant injured in transport accident
0.661 0.339 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.661 0.339 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.661 0.339 0.000
V40-V49 Car occupant injured in transport accident
0.661 0.339 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.661 0.339 0.000
V01-V09 Pedestrian injured in transport accident
0.661 0.339 0.000
B02 Zoster [herpes zoster]
0.660 0.340 0.000
J35 Chronic diseases of tonsils and adenoids
0.660 0.340 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.660 0.340 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.660 0.340 0.000
R50 Fever of unknown origin
0.659 0.341 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.658 0.342 0.000
B37.8 Candidiasis of other sites
0.658 0.342 0.000
Z99.8 Dependence on other enabling machines and devices
0.657 0.343 0.000
J43.8 Other emphysema
0.657 0.343 0.000
J43.2 Centrilobular emphysema
0.657 0.343 0.000
J43.1 Panlobular emphysema
0.657 0.343 0.000
J43.0 MacLeod's syndrome
0.657 0.343 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.657 0.343 0.000
G41 Status epilepticus
0.657 0.343 0.000
Y40 Systemic antibiotics
0.657 0.343 0.000
Z29 Need for other prophylactic measures
0.657 0.343 0.000
Z98.0 Intestinal bypass and anastomosis status
0.656 0.344 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.656 0.344 0.000
S50 Superficial injury of forearm
0.655 0.344 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.655 0.345 0.000
S00-S09 Injuries to the head
0.654 0.346 0.000
Z91.5 Personal history of self-harm
0.654 0.346 0.000
S89.9 Unspecified injury of lower leg
0.654 0.346 0.000
V20-V29 Motorcycle rider injured in transport accident
0.654 0.346 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.653 0.347 0.000
B37.0 Candidal stomatitis
0.653 0.347 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.653 0.347 0.000
J93 Pneumothorax
0.652 0.347 0.000
G11 Hereditary ataxia
0.652 0.348 0.000
A08.4 Viral intestinal infection, unspecified
0.652 0.348 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.651 0.349 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.651 0.349 0.000
T39.4 Antirheumatics, not elsewhere classified
0.651 0.349 0.000
T39.2 Pyrazolone derivatives
0.651 0.349 0.000
S88 Traumatic amputation of lower leg
0.651 0.349 0.000
S87 Crushing injury of lower leg
0.651 0.349 0.000
S86 Injury of muscle and tendon at lower leg level
0.651 0.349 0.000
S85 Injury of blood vessels at lower leg level
0.651 0.349 0.000
S84 Injury of nerves at lower leg level
0.651 0.349 0.000
S51 Open wound of forearm
0.650 0.350 0.000
M13.8 Other specified arthritis
0.650 0.350 0.000
M13.1 Monoarthritis, not elsewhere classified
0.650 0.350 0.000
H40-H42 Glaucoma
0.649 0.351 0.000
T85.2 Mechanical complication of intraocular lens
0.649 0.351 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.647 0.353 0.000
M11 Other crystal arthropathies
0.647 0.353 0.000
R63.6 Insufficient intake of food and water due to self neglect
0.645 0.355 0.000
R63.5 Abnormal weight gain
0.645 0.355 0.000
R63.3 Feeding difficulties and mismanagement
0.645 0.355 0.000
R63.2 Polyphagia
0.645 0.355 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.645 0.355 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.645 0.355 0.000
M48.54 Collapsed vertebra, not elsewhere classified (Thoracic region)
0.644 0.356 0.000
C77.1 Intrathoracic lymph nodes
0.644 0.356 0.000
Z98.8 Other specified postsurgical states
0.644 0.356 0.000
C77.2 Intra-abdominal lymph nodes
0.643 0.357 0.000
C85.1 B-cell lymphoma, unspecified
0.643 0.357 0.000
B37.9 Candidiasis, unspecified
0.642 0.357 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.642 0.358 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.641 0.359 0.000
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)
0.641 0.359 0.000
C92 Myeloid leukaemia
0.640 0.360 0.000
G40.8 Other epilepsy
0.640 0.360 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.640 0.360 0.000
G40.5 Special epileptic syndromes
0.640 0.360 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.640 0.360 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.640 0.360 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.640 0.360 0.000
H53.1 Subjective visual disturbances
0.640 0.360 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.640 0.360 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.640 0.360 0.000
R27.0 Ataxia, unspecified
0.639 0.361 0.000
R20 Disturbances of skin sensation
0.639 0.361 0.000
M75 Shoulder lesions
0.639 0.361 0.000
B48 Other mycoses, not elsewhere classified
0.638 0.362 0.000
B47 Mycetoma
0.638 0.362 0.000
B46 Zygomycosis
0.638 0.362 0.000
B45 Cryptococcosis
0.638 0.362 0.000
B44 Aspergillosis
0.638 0.362 0.000
B43 Chromomycosis and phaeomycotic abscess
0.638 0.362 0.000
B42 Sporotrichosis
0.638 0.362 0.000
B41 Paracoccidioidomycosis
0.638 0.362 0.000
B40 Blastomycosis
0.638 0.362 0.000
B39 Histoplasmosis
0.638 0.362 0.000
B38 Coccidioidomycosis
0.638 0.362 0.000
B36 Other superficial mycoses
0.638 0.362 0.000
B49 Unspecified mycosis
0.638 0.362 0.000
H57 Other disorders of eye and adnexa
0.638 0.362 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.637 0.363 0.000
F60 Specific personality disorders
0.637 0.363 0.000
J04 Acute laryngitis and tracheitis
0.637 0.363 0.000
G61 Inflammatory polyneuropathy
0.636 0.364 0.000
G44 Other headache syndromes
0.636 0.364 0.000
G93.3 Postviral fatigue syndrome
0.635 0.365 0.000
S82.2 Fracture of shaft of tibia
0.635 0.365 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.634 0.366 0.000
R63.4 Abnormal weight loss
0.634 0.366 0.000
T98 Sequelae of other and unspecified effects of external causes
0.633 0.367 0.000
T95 Sequelae of burns, corrosions and frostbite
0.633 0.367 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.633 0.367 0.000
T91 Sequelae of injuries of neck and trunk
0.633 0.367 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.633 0.367 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.633 0.367 0.000
M46.92 Inflammatory spondylopathy, unspecified (Cervical region)
0.633 0.367 0.000
H54.9 Unspecified visual impairment (binocular)
0.633 0.367 0.000
H54.7 Unspecified visual loss
0.632 0.368 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.632 0.368 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.632 0.368 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.632 0.368 0.000
F70-F79 Mental retardation
0.632 0.368 0.000
W08.0 Home
0.632 0.368 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.631 0.368 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.631 0.369 0.000
W13 Fall from, out of or through building or structure
0.631 0.369 0.000
J30 Vasomotor and allergic rhinitis
0.631 0.369 0.000
M80 Osteoporosis with pathological fracture
0.631 0.369 0.000
C43 Malignant melanoma of skin
0.631 0.369 0.000
S68 Traumatic amputation of wrist and hand
0.630 0.370 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.630 0.370 0.000
C32 Malignant neoplasm of larynx
0.630 0.370 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.630 0.370 0.000
G96 Other disorders of central nervous system
0.630 0.370 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.630 0.370 0.000
G90 Disorders of autonomic nervous system
0.630 0.370 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.630 0.370 0.000
G92 Toxic encephalopathy
0.630 0.370 0.000
M13.93 Arthritis, unspecified (Forearm)
0.629 0.370 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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