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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs117903119
log Bayes Factor = 9.06456
Chromosome 21   position 46,716,223  (GRCh37) Explore rs117903119 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.999 0.001 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XX External causes of morbidity and mortality
0.998 0.002 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.998 0.002 0.000
Z88.0 Personal history of allergy to penicillin
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.997 0.003 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.994 0.006 0.000
Chapter XXI Factors influencing health status and contact with health services
0.989 0.011 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.988 0.012 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.983 0.017 0.000
Y86 Sequelae of other accidents
0.979 0.021 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.979 0.021 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.977 0.023 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.977 0.023 0.000
Chapter IX Diseases of the circulatory system
0.976 0.024 0.000
C79 Secondary malignant neoplasm of other sites
0.976 0.024 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.972 0.028 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.970 0.030 0.000
F30-F39 Mood [affective] disorders
0.969 0.031 0.000
Z53.8 Procedure not carried out for other reasons
0.968 0.032 0.000
I30-I52 Other forms of heart disease
0.965 0.035 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.963 0.037 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.962 0.038 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.955 0.045 0.000
L03 Cellulitis
0.952 0.048 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.949 0.051 0.000
F41 Other anxiety disorders
0.948 0.052 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.946 0.054 0.000
C78.2 Secondary malignant neoplasm of pleura
0.940 0.060 0.000
I49 Other cardiac arrhythmias
0.939 0.061 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.938 0.062 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.937 0.063 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.936 0.064 0.000
Z94 Transplanted organ and tissue status
0.933 0.067 0.000
Z88.6 Personal history of allergy to analgesic agent
0.933 0.067 0.000
F32 Depressive episode
0.933 0.067 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.930 0.070 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.928 0.072 0.000
L08 Other local infections of skin and subcutaneous tissue
0.928 0.072 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.922 0.078 0.000
Z88.5 Personal history of allergy to narcotic agent
0.920 0.080 0.000
F32.9 Depressive episode, unspecified
0.915 0.085 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.915 0.085 0.000
F41.9 Anxiety disorder, unspecified
0.909 0.091 0.000
Chapter I Certain infectious and parasitic diseases
0.903 0.097 0.000
I45 Other conduction disorders
0.903 0.097 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.899 0.101 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.898 0.102 0.000
I20-I25 Ischaemic heart diseases
0.897 0.103 0.000
L08.9 Local infection of skin and subcutaneous tissue, unspecified
0.897 0.103 0.000
Z50 Care involving use of rehabilitation procedures
0.891 0.109 0.000
L03.1 Cellulitis of other parts of limb
0.890 0.110 0.000
T39.1 4-Aminophenol derivatives
0.889 0.111 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.886 0.114 0.000
T66-T78 Other and unspecified effects of external causes
0.883 0.117 0.000
I10-I15 Hypertensive diseases
0.883 0.117 0.000
I25 Chronic ischaemic heart disease
0.883 0.117 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.881 0.119 0.000
C91 Lymphoid leukaemia
0.876 0.124 0.000
I49.3 Ventricular premature depolarisation
0.873 0.127 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.871 0.129 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.869 0.131 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.868 0.132 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.864 0.136 0.000
I47 Paroxysmal tachycardia
0.862 0.138 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.858 0.142 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.856 0.144 0.000
F20 Schizophrenia
0.854 0.146 0.000
L03.9 Cellulitis, unspecified
0.854 0.146 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.853 0.147 0.000
C81 Hodgkin's disease
0.851 0.149 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.850 0.150 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.849 0.151 0.000
Z45 Adjustment and management of implanted device
0.847 0.153 0.000
C80 Malignant neoplasm without specification of site
0.846 0.154 0.000
C92 Myeloid leukaemia
0.841 0.159 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.838 0.162 0.000
Z94.0 Kidney transplant status
0.837 0.163 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.836 0.164 0.000
L20-L30 Dermatitis and eczema
0.833 0.167 0.000
C64-C68 Malignant neoplasms of urinary tract
0.832 0.168 0.000
T43.2 Other and unspecified antidepressants
0.831 0.169 0.000
Z96 Presence of other functional implants
0.831 0.169 0.000
I25.1 Atherosclerotic heart disease
0.831 0.169 0.000
C51-C58 Malignant neoplasms of female genital organs
0.831 0.169 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.829 0.171 0.000
I49.4 Other and unspecified premature depolarisation
0.828 0.172 0.000
F41.2 Mixed anxiety and depressive disorder
0.827 0.173 0.000
T40.2 Other opioids
0.827 0.173 0.000
I45.6 Preexcitation syndrome
0.825 0.175 0.000
C78.7 Secondary malignant neoplasm of liver
0.824 0.176 0.000
Z94.8 Other transplanted organ and tissue status
0.819 0.181 0.000
I34 Nonrheumatic mitral valve disorders
0.818 0.182 0.000
I47.2 Ventricular tachycardia
0.817 0.183 0.000
X60-X84 Intentional self-harm
0.816 0.184 0.000
I10 Essential (primary) hypertension
0.813 0.187 0.000
A30-A49 Other bacterial diseases
0.813 0.187 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.190 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.808 0.192 0.000
I49.0 Ventricular fibrillation and flutter
0.808 0.192 0.000
Z53.0 Procedure not carried out because of contraindication
0.807 0.193 0.000
V40-V49 Car occupant injured in transport accident
0.805 0.195 0.000
C95 Leukaemia of unspecified cell type
0.804 0.196 0.000
Z42 Follow-up care involving plastic surgery
0.800 0.200 0.000
L03.2 Cellulitis of face
0.799 0.201 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.797 0.203 0.000
T92 Sequelae of injuries of upper limb
0.797 0.203 0.000
L50-L54 Urticaria and erythema
0.794 0.206 0.000
F31 Bipolar affective disorder
0.793 0.207 0.000
T78 Adverse effects, not elsewhere classified
0.792 0.208 0.000
Z96.1 Presence of intraocular lens
0.792 0.208 0.000
M45-M49 Spondylopathies
0.791 0.209 0.000
Z97 Presence of other devices
0.791 0.209 0.000
Z49 Care involving dialysis
0.790 0.210 0.000
Z89 Acquired absence of limb
0.789 0.211 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.787 0.213 0.000
W50-W64 Exposure to animate mechanical forces
0.787 0.213 0.000
C91.1 Chronic lymphocytic leukaemia
0.786 0.214 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.786 0.214 0.000
I22 Subsequent myocardial infarction
0.786 0.214 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.785 0.215 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.785 0.215 0.000
F60-F69 Disorders of adult personality and behaviour
0.784 0.216 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.783 0.217 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.783 0.217 0.000
C79.6 Secondary malignant neoplasm of ovary
0.782 0.217 0.000
T51 Toxic effect of alcohol
0.782 0.218 0.000
F70-F79 Mental retardation
0.782 0.218 0.000
L27 Dermatitis due to substances taken internally
0.781 0.219 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.777 0.223 0.000
F41.1 Generalised anxiety disorder
0.776 0.224 0.000
M40-M43 Deforming dorsopathies
0.776 0.224 0.000
Z50.8 Care involving use of rehabilitation procedures
0.776 0.224 0.000
Y85 Sequelae of transport accidents
0.776 0.224 0.000
I36 Nonrheumatic tricuspid valve disorders
0.775 0.225 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.775 0.225 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.774 0.226 0.000
X10-X19 Contact with heat and hot substances
0.774 0.226 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.774 0.226 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.773 0.227 0.000
X50-X57 Overexertion, travel and privation
0.773 0.227 0.000
F20.0 Paranoid schizophrenia
0.772 0.228 0.000
S50-S59 Injuries to the elbow and forearm
0.771 0.229 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.770 0.230 0.000
I49.1 Atrial premature depolarisation
0.767 0.233 0.000
F80-F89 Disorders of psychological development
0.766 0.234 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.765 0.235 0.000
T82.3 Mechanical complication of other vascular grafts
0.764 0.236 0.000
Z94.4 Liver transplant status
0.761 0.239 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.761 0.239 0.000
I31 Other diseases of pericardium
0.761 0.239 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.760 0.240 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.758 0.241 0.000
Z43 Attention to artificial openings
0.758 0.242 0.000
C78.0 Secondary malignant neoplasm of lung
0.757 0.243 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.757 0.243 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.755 0.245 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.755 0.245 0.000
F34 Persistent mood [affective] disorders
0.754 0.246 0.000
M47 Spondylosis
0.754 0.246 0.000
Z94.1 Heart transplant status
0.753 0.247 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.753 0.247 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.753 0.247 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.752 0.248 0.000
Z44 Fitting and adjustment of external prosthetic device
0.751 0.248 0.000
B15-B19 Viral hepatitis
0.751 0.249 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.748 0.251 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.745 0.255 0.000
A41 Other septicaemia
0.745 0.255 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.744 0.256 0.000
B35-B49 Mycoses
0.743 0.257 0.000
T98 Sequelae of other and unspecified effects of external causes
0.743 0.257 0.000
T87 Complications peculiar to reattachment and amputation
0.740 0.260 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.740 0.260 0.000
Y45.1 Salicylates
0.739 0.261 0.000
T88.6 Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
0.738 0.262 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.737 0.263 0.000
I25.3 Aneurysm of heart
0.737 0.263 0.000
L03.0 Cellulitis of finger and toe
0.737 0.263 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.736 0.264 0.000
T90 Sequelae of injuries of head
0.735 0.265 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.733 0.267 0.000
S10-S19 Injuries to the neck
0.733 0.267 0.000
C80.9 Malignant neoplasm, unspecified
0.731 0.269 0.000
Q80-Q89 Other congenital malformations
0.728 0.272 0.000
C81.9 Hodgkin's disease, unspecified
0.727 0.273 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.727 0.273 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.725 0.275 0.000
F22 Persistent delusional disorders
0.724 0.276 0.000
I45.2 Bifascicular block
0.724 0.276 0.000
Y45.5 4-Aminophenol derivatives
0.722 0.278 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.722 0.278 0.000
S20-S29 Injuries to the thorax
0.722 0.278 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.721 0.279 0.000
D47.4 Osteomyelofibrosis
0.719 0.281 0.000
I45.8 Other specified conduction disorders
0.719 0.281 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.719 0.281 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.719 0.281 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.719 0.281 0.000
Z54 Convalescence
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.716 0.284 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.716 0.284 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.716 0.284 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.716 0.284 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.716 0.284 0.000
T36 Poisoning by systemic antibiotics
0.716 0.284 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.716 0.284 0.000
Y35-Y36 Legal intervention and operations of war
0.716 0.284 0.000
Y10-Y34 Event of undetermined intent
0.716 0.284 0.000
Y00-Y09 Assault
0.716 0.284 0.000
X85-X99 Assault
0.716 0.284 0.000
X30-X39 Exposure to forces of nature
0.716 0.284 0.000
X00-X09 Exposure to smoke, fire and flames
0.716 0.284 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.716 0.284 0.000
W75-W84 Other accidental threats to breathing
0.716 0.284 0.000
W65-W74 Accidental drowning and submersion
0.716 0.284 0.000
V98-V99 Other and unspecified transport accidents
0.716 0.284 0.000
V95-V97 Air and space transport accidents
0.716 0.284 0.000
V90-V94 Water transport accidents
0.716 0.284 0.000
V80-V89 Other land transport accidents
0.716 0.284 0.000
V70-V79 Bus occupant injured in transport accident
0.716 0.284 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.716 0.284 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.716 0.284 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.716 0.284 0.000
V01-V09 Pedestrian injured in transport accident
0.716 0.284 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
M43 Other deforming dorsopathies
0.715 0.285 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.715 0.285 0.000
I33 Acute and subacute endocarditis
0.714 0.285 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.713 0.287 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
F32.0 Mild depressive episode
0.712 0.288 0.000
Chapter XXII Codes for special purposes
0.711 0.289 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.709 0.290 0.000
Y89 Sequelae of other external causes
0.708 0.292 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.708 0.292 0.000
Y60.0 During surgical operation
0.708 0.292 0.000
C54 Malignant neoplasm of corpus uteri
0.707 0.293 0.000
C92.0 Acute myeloid leukaemia
0.706 0.294 0.000
Z84 Family history of other conditions
0.706 0.294 0.000
I49.5 Sick sinus syndrome
0.706 0.294 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.703 0.297 0.000
C88 Malignant immunoproliferative diseases
0.702 0.298 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.702 0.298 0.000
C94 Other leukaemias of specified cell type
0.702 0.298 0.000
C93 Monocytic leukaemia
0.702 0.298 0.000
C86 Other specified types of T/NK-cell lymphoma
0.702 0.298 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.702 0.298 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.702 0.298 0.000
B99-B99 Other infectious diseases
0.701 0.299 0.000
T59 Toxic effect of other gases, fumes and vapours
0.701 0.299 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.701 0.299 0.000
F30 Manic episode
0.701 0.299 0.000
T51.0 Ethanol
0.701 0.299 0.000
L10-L14 Bullous disorders
0.701 0.299 0.000
F29 Unspecified nonorganic psychosis
0.700 0.300 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.700 0.300 0.000
C83.3 Large cell (diffuse)
0.700 0.300 0.000
Y40 Systemic antibiotics
0.700 0.300 0.000
I00-I02 Acute rheumatic fever
0.700 0.300 0.000
S50 Superficial injury of forearm
0.700 0.300 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.700 0.300 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.700 0.300 0.000
F42 Obsessive-compulsive disorder
0.699 0.300 0.000
T58 Toxic effect of carbon monoxide
0.699 0.301 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.698 0.302 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.698 0.302 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.697 0.302 0.000
Z52 Donors of organs and tissues
0.697 0.303 0.000
L04 Acute lymphadenitis
0.696 0.304 0.000
L01 Impetigo
0.696 0.304 0.000
L00 Staphylococcal scalded skin syndrome
0.696 0.304 0.000
T93 Sequelae of injuries of lower limb
0.695 0.305 0.000
F38 Other mood [affective] disorders
0.695 0.305 0.000
F39 Unspecified mood [affective] disorder
0.695 0.305 0.000
I34.0 Mitral (valve) insufficiency
0.695 0.305 0.000
M50-M54 Other dorsopathies
0.693 0.307 0.000
M47.9 Spondylosis, unspecified
0.693 0.307 0.000
I37 Pulmonary valve disorders
0.693 0.307 0.000
I52 Other heart disorders in diseases classified elsewhere
0.692 0.308 0.000
I48 Atrial fibrillation and flutter
0.692 0.308 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.692 0.308 0.000
I41 Myocarditis in diseases classified elsewhere
0.692 0.308 0.000
I40 Acute myocarditis
0.692 0.308 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.692 0.308 0.000
I32 Pericarditis in diseases classified elsewhere
0.692 0.308 0.000
C83.1 Small cleaved cell (diffuse)
0.692 0.308 0.000
F20.9 Schizophrenia, unspecified
0.692 0.308 0.000
Z96.2 Presence of otological and audiological implants
0.690 0.310 0.000
T21 Burn and corrosion of trunk
0.690 0.310 0.000
F48 Other neurotic disorders
0.689 0.311 0.000
F44 Dissociative [conversion] disorders
0.689 0.311 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.689 0.311 0.000
Z51 Other medical care
0.689 0.311 0.000
T92.1 Sequelae of fracture of arm
0.688 0.312 0.000
M86-M90 Other osteopathies
0.688 0.312 0.000
T23 Burn and corrosion of wrist and hand
0.688 0.312 0.000
F23 Acute and transient psychotic disorders
0.687 0.313 0.000
I30 Acute pericarditis
0.687 0.313 0.000
M47.8 Other spondylosis
0.686 0.314 0.000
I47.0 Reentry ventricular arrhythmia
0.686 0.314 0.000
Y59 Other and unspecified vaccines and biological substances
0.685 0.315 0.000
Y58 Bacterial vaccines
0.685 0.315 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.685 0.315 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.685 0.315 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.685 0.315 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.685 0.315 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.685 0.315 0.000
Y48 Anaesthetics and therapeutic gases
0.685 0.315 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.685 0.315 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.685 0.315 0.000
L53 Other erythematous conditions
0.684 0.316 0.000
L23 Allergic contact dermatitis
0.684 0.316 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.684 0.316 0.000
Z80 Family history of malignant neoplasm
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.681 0.319 0.000
F99-F99 Unspecified mental disorder
0.681 0.319 0.000
T78.4 Allergy, unspecified
0.681 0.319 0.000
I15 Secondary hypertension
0.680 0.320 0.000
L05 Pilonidal cyst
0.680 0.320 0.000
I31.9 Disease of pericardium, unspecified
0.680 0.320 0.000
F45 Somatoform disorders
0.680 0.320 0.000
F41.8 Other specified anxiety disorders
0.679 0.321 0.000
F41.3 Other mixed anxiety disorders
0.679 0.321 0.000
C95.9 Leukaemia, unspecified
0.679 0.321 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.678 0.322 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.678 0.322 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.678 0.322 0.000
T42.3 Barbiturates
0.678 0.322 0.000
T42.2 Succinimides and oxazolidinediones
0.678 0.322 0.000
T42.1 Iminostilbenes
0.678 0.322 0.000
T42.0 Hydantoin derivatives
0.678 0.322 0.000
D00-D09 In situ neoplasms
0.678 0.322 0.000
T86 Failure and rejection of transplanted organs and tissues
0.678 0.322 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.322 0.000
M91-M94 Chondropathies
0.678 0.322 0.000
I46 Cardiac arrest
0.676 0.324 0.000
D60-D64 Aplastic and other anaemias
0.676 0.324 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.675 0.325 0.000
C81.1 Nodular sclerosis
0.674 0.326 0.000
C91.0 Acute lymphoblastic leukaemia
0.674 0.326 0.000
L08.8 Other specified local infections of skin and subcutaneous tissue
0.673 0.327 0.000
I49.2 Junctional premature depolarisation
0.673 0.327 0.000
T20 Burn and corrosion of head and neck
0.673 0.327 0.000
M43.1 Spondylolisthesis
0.672 0.328 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.672 0.328 0.000
T43.9 Psychotropic drug, unspecified
0.672 0.328 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.672 0.328 0.000
T43.6 Psychostimulants with abuse potential
0.672 0.328 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.672 0.328 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.672 0.328 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.671 0.329 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.671 0.329 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.671 0.329 0.000
I42 Cardiomyopathy
0.669 0.331 0.000
L03.8 Cellulitis of other sites
0.669 0.331 0.000
Z94.9 Transplanted organ and tissue status, unspecified
0.669 0.331 0.000
Z94.6 Bone transplant status
0.669 0.331 0.000
Z94.5 Skin transplant status
0.669 0.331 0.000
Z94.3 Heart and lungs transplant status
0.669 0.331 0.000
Z94.2 Lung transplant status
0.669 0.331 0.000
F32.8 Other depressive episodes
0.669 0.331 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.669 0.331 0.000
V10-V19 Pedal cyclist injured in transport accident
0.668 0.331 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.668 0.332 0.000
I25.4 Coronary artery aneurysm
0.667 0.332 0.000
Z81 Family history of mental and behavioural disorders
0.667 0.333 0.000
F25 Schizoaffective disorders
0.667 0.333 0.000
F28 Other nonorganic psychotic disorders
0.667 0.333 0.000
F24 Induced delusional disorder
0.667 0.333 0.000
F21 Schizotypal disorder
0.667 0.333 0.000
C92.1 Chronic myeloid leukaemia
0.666 0.333 0.000
V48 Car occupant injured in noncollision transport accident
0.666 0.334 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.665 0.334 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.665 0.335 0.000
T39.4 Antirheumatics, not elsewhere classified
0.665 0.335 0.000
T39.2 Pyrazolone derivatives
0.665 0.335 0.000
L08.1 Erythrasma
0.665 0.335 0.000
L08.0 Pyoderma
0.665 0.335 0.000
T90.4 Sequelae of injury of eye and orbit
0.664 0.336 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.664 0.336 0.000
I45.5 Other specified heart block
0.663 0.336 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.663 0.337 0.000
I60-I69 Cerebrovascular diseases
0.662 0.338 0.000
I34.2 Nonrheumatic mitral (valve) stenosis
0.662 0.338 0.000
Z89.4 Acquired absence of foot and ankle
0.662 0.338 0.000
Z45.1 Adjustment and management of infusion pump
0.661 0.339 0.000
T95 Sequelae of burns, corrosions and frostbite
0.661 0.339 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.661 0.339 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.661 0.339 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.661 0.339 0.000
Z53.9 Procedure not carried out, unspecified reason
0.660 0.340 0.000
T82.1 Mechanical complication of cardiac electronic device
0.660 0.340 0.000
Y44 Agents primarily affecting blood constituents
0.660 0.340 0.000
Z41 Procedures for purposes other than remedying health state
0.660 0.340 0.000
Z49.0 Preparatory care for dialysis
0.659 0.341 0.000
F33 Recurrent depressive disorder
0.659 0.341 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.658 0.341 0.000
C66 Malignant neoplasm of ureter
0.657 0.343 0.000
I24 Other acute ischaemic heart diseases
0.656 0.344 0.000
T68 Hypothermia
0.656 0.344 0.000
D47.1 Chronic myeloproliferative disease
0.656 0.344 0.000
S70-S79 Injuries to the hip and thigh
0.655 0.345 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.655 0.345 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.655 0.345 0.000
M46 Other inflammatory spondylopathies
0.654 0.346 0.000
Z50.0 Cardiac rehabilitation
0.652 0.348 0.000
Z45.2 Adjustment and management of vascular access device
0.652 0.348 0.000
Z97.5 Presence of (intra-uterine) contraceptive device
0.651 0.349 0.000
C65 Malignant neoplasm of renal pelvis
0.651 0.349 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.650 0.349 0.000
Y52 Agents primarily affecting the cardiovascular system
0.650 0.350 0.000
Z47 Other orthopaedic follow-up care
0.650 0.350 0.000
Q00-Q07 Congenital malformations of the nervous system
0.649 0.351 0.000
T91 Sequelae of injuries of neck and trunk
0.649 0.351 0.000
Z45.8 Adjustment and management of other implanted devices
0.649 0.351 0.000
Y88 Sequelae of surgical and medical care as external cause
0.648 0.351 0.000
C83.0 Small cell (diffuse)
0.648 0.352 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.647 0.352 0.000
B65-B83 Helminthiases
0.647 0.352 0.000
B50-B64 Protozoal diseases
0.647 0.352 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.647 0.352 0.000
A75-A79 Rickettsioses
0.647 0.352 0.000
A70-A74 Other diseases caused by chlamydiae
0.647 0.352 0.000
A65-A69 Other spirochaetal diseases
0.647 0.352 0.000
A20-A28 Certain zoonotic bacterial diseases
0.647 0.352 0.000
A15-A19 Tuberculosis
0.647 0.352 0.000
I45.4 Nonspecific intraventricular block
0.647 0.353 0.000
I45.3 Trifascicular block
0.647 0.353 0.000
I45.0 Right fascicular block
0.647 0.353 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.647 0.353 0.000
I49.8 Other specified cardiac arrhythmias
0.646 0.354 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.646 0.354 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.645 0.354 0.000
I45.1 Other and unspecified right bundle-branch block
0.645 0.355 0.000
T40.9 Other and unspecified psychodysleptics [hallucinogens]
0.644 0.355 0.000
T40.8 Lysergide [LSD]
0.644 0.355 0.000
T40.7 Cannabis (derivatives)
0.644 0.355 0.000
T40.6 Other and unspecified narcotics
0.644 0.355 0.000
T40.5 Cocaine
0.644 0.355 0.000
T40.4 Other synthetic narcotics
0.644 0.355 0.000
T40.3 Methadone
0.644 0.355 0.000
T40.1 Heroin
0.644 0.355 0.000
T40.0 Opium
0.644 0.355 0.000
T65 Toxic effect of other and unspecified substances
0.644 0.356 0.000
T62 Toxic effect of other noxious substances eaten as food
0.644 0.356 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.644 0.356 0.000
T60 Toxic effect of pesticides
0.644 0.356 0.000
T57 Toxic effect of other inorganic substances
0.644 0.356 0.000
T56 Toxic effect of metals
0.644 0.356 0.000
T54 Toxic effect of corrosive substances
0.644 0.356 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.644 0.356 0.000
T52 Toxic effect of organic solvents
0.644 0.356 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.644 0.356 0.000
T55 Toxic effect of soaps and detergents
0.644 0.356 0.000
T78.3 Angioneurotic oedema
0.644 0.356 0.000
I23 Certain current complications following acute myocardial infarction
0.643 0.357 0.000
S50.0 Contusion of elbow
0.642 0.358 0.000
Z97.0 Presence of artificial eye
0.642 0.358 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.641 0.359 0.000
T88.5 Other complications of anaesthesia
0.639 0.360 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.639 0.361 0.000
I36.1 Nonrheumatic tricuspid (valve) insufficiency
0.639 0.361 0.000
M60-M63 Disorders of muscles
0.639 0.361 0.000
Z50.6 Orthoptic training
0.638 0.361 0.000
Z50.3 Drug rehabilitation
0.638 0.361 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.638 0.362 0.000
S99 Other and unspecified injuries of ankle and foot
0.638 0.362 0.000
T63 Toxic effect of contact with venomous animals
0.637 0.363 0.000
A80-A89 Viral infections of the central nervous system
0.636 0.364 0.000
A41.5 Septicaemia due to other Gram-negative organisms
0.636 0.364 0.000
I38 Endocarditis, valve unspecified
0.635 0.364 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.635 0.365 0.000
W55 Bitten or struck by other mammals
0.635 0.365 0.000
M80-M85 Disorders of bone density and structure
0.635 0.365 0.000
Q85 Phakomatoses, not elsewhere classified
0.635 0.365 0.000
I34.9 Nonrheumatic mitral valve disorder, unspecified
0.634 0.366 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.634 0.366 0.000
I13 Hypertensive heart and renal disease
0.633 0.367 0.000
T75 Effects of other external causes
0.633 0.367 0.000
T74 Maltreatment syndromes
0.633 0.367 0.000
T73 Effects of other deprivation
0.633 0.367 0.000
T70 Effects of air pressure and water pressure
0.633 0.367 0.000
T69 Other effects of reduced temperature
0.633 0.367 0.000
T67 Effects of heat and light
0.633 0.367 0.000
T71 Asphyxiation
0.633 0.367 0.000
T66 Unspecified effects of radiation
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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