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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118008540
log Bayes Factor = 14.4387
Chromosome 6   position 111,739,245  (GRCh37) Explore rs118008540 on Ensembl!
Variant rs118008540 is part of Cluster X0132

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C15-C26 Malignant neoplasms of digestive organs
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z51 Other medical care
0.999 0.001 0.000
C18 Malignant neoplasm of colon
0.998 0.002 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.998 0.002 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.996 0.004 0.000
C15 Malignant neoplasm of oesophagus
0.996 0.004 0.000
Z51.1 Chemotherapy session for neoplasm
0.995 0.005 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.995 0.005 0.000
C15.9 Oesophagus, unspecified
0.984 0.016 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.979 0.021 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.976 0.024 0.000
Chapter V Mental and behavioural disorders
0.976 0.024 0.000
S00-S09 Injuries to the head
0.968 0.032 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.962 0.038 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.958 0.042 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.956 0.044 0.000
T39.1 4-Aminophenol derivatives
0.955 0.045 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.951 0.049 0.000
C78.7 Secondary malignant neoplasm of liver
0.949 0.051 0.000
D60-D64 Aplastic and other anaemias
0.949 0.051 0.000
F10.1 Harmful use
0.931 0.069 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.931 0.069 0.000
Z48 Other surgical follow-up care
0.927 0.073 0.000
F10.2 Dependence syndrome
0.926 0.074 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.920 0.080 0.000
S40-S49 Injuries to the shoulder and upper arm
0.920 0.080 0.000
S80-S89 Injuries to the knee and lower leg
0.919 0.081 0.000
Chapter XX External causes of morbidity and mortality
0.918 0.082 0.000
C18.3 Hepatic flexure
0.912 0.088 0.000
S20-S29 Injuries to the thorax
0.912 0.088 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.912 0.088 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.909 0.091 0.000
S06 Intracranial injury
0.907 0.093 0.000
C77.0 Lymph nodes of head, face and neck
0.902 0.098 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.902 0.098 0.000
Chapter VIII Diseases of the ear and mastoid process
0.899 0.101 0.000
C18.9 Colon, unspecified
0.897 0.103 0.000
D64 Other anaemias
0.896 0.103 0.000
C51-C58 Malignant neoplasms of female genital organs
0.886 0.114 0.000
C15.5 Lower third of oesophagus
0.884 0.116 0.000
Z43 Attention to artificial openings
0.876 0.124 0.000
M15-M19 Arthrosis
0.873 0.127 0.000
C16 Malignant neoplasm of stomach
0.870 0.130 0.000
C18.2 Ascending colon
0.870 0.130 0.000
Chapter XIV Diseases of the genitourinary system
0.870 0.130 0.000
M20-M25 Other joint disorders
0.867 0.133 0.000
S01 Open wound of head
0.862 0.138 0.000
D50-D53 Nutritional anaemias
0.860 0.140 0.000
Z51.0 Radiotherapy session
0.856 0.144 0.000
Z50 Care involving use of rehabilitation procedures
0.856 0.144 0.000
D69 Purpura and other haemorrhagic conditions
0.851 0.149 0.000
M19 Other arthrosis
0.850 0.150 0.000
Z45 Adjustment and management of implanted device
0.848 0.152 0.000
M86-M90 Other osteopathies
0.847 0.153 0.000
C77.3 Axillary and upper limb lymph nodes
0.846 0.154 0.000
C18.6 Descending colon
0.843 0.157 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.841 0.159 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.841 0.159 0.000
C18.5 Splenic flexure
0.839 0.161 0.000
Z42 Follow-up care involving plastic surgery
0.837 0.163 0.000
W00-W19 Falls
0.834 0.166 0.000
S01.8 Open wound of other parts of head
0.833 0.167 0.000
Z51.3 Blood transfusion without reported diagnosis
0.831 0.169 0.000
D00-D09 In situ neoplasms
0.831 0.169 0.000
D64.9 Anaemia, unspecified
0.830 0.170 0.000
M19.9 Arthrosis, unspecified
0.829 0.171 0.000
Z51.5 Palliative care
0.828 0.172 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.827 0.173 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.826 0.174 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.826 0.174 0.000
C18.4 Transverse colon
0.814 0.186 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.814 0.186 0.000
Z51.8 Other specified medical care
0.813 0.187 0.000
C56 Malignant neoplasm of ovary
0.813 0.187 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.810 0.190 0.000
Chapter XXII Codes for special purposes
0.806 0.194 0.000
C18.7 Sigmoid colon
0.805 0.195 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.805 0.195 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.802 0.198 0.000
D69.6 Thrombocytopenia, unspecified
0.800 0.200 0.000
Z48.0 Attention to surgical dressings and sutures
0.800 0.200 0.000
C15.4 Middle third of oesophagus
0.799 0.201 0.000
Chapter X Diseases of the respiratory system
0.798 0.202 0.000
S82 Fracture of lower leg, including ankle
0.798 0.202 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.797 0.203 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.795 0.205 0.000
C79 Secondary malignant neoplasm of other sites
0.793 0.207 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.793 0.207 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.793 0.207 0.000
F10.3 Withdrawal state
0.792 0.208 0.000
C01 Malignant neoplasm of base of tongue
0.791 0.209 0.000
X60-X84 Intentional self-harm
0.790 0.210 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.790 0.210 0.000
Z43.1 Attention to gastrostomy
0.789 0.211 0.000
S29 Other and unspecified injuries of thorax
0.789 0.211 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.788 0.212 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.787 0.213 0.000
D62 Acute posthaemorrhagic anaemia
0.786 0.214 0.000
D50 Iron deficiency anaemia
0.786 0.214 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.786 0.214 0.000
D68 Other coagulation defects
0.781 0.219 0.000
S09 Other and unspecified injuries of head
0.780 0.220 0.000
Z46 Fitting and adjustment of other devices
0.778 0.222 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.778 0.222 0.000
S81 Open wound of lower leg
0.777 0.223 0.000
H80-H83 Diseases of inner ear
0.777 0.223 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.776 0.224 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.775 0.225 0.000
S42 Fracture of shoulder and upper arm
0.773 0.227 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.773 0.227 0.000
N00-N08 Glomerular diseases
0.771 0.229 0.000
Z48.9 Surgical follow-up care, unspecified
0.770 0.230 0.000
T92 Sequelae of injuries of upper limb
0.769 0.231 0.000
D80-D89 Certain disorders involving the immune mechanism
0.768 0.231 0.000
Z41 Procedures for purposes other than remedying health state
0.767 0.233 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.766 0.234 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.766 0.234 0.000
Z53.9 Procedure not carried out, unspecified reason
0.765 0.235 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.764 0.236 0.000
M24 Other specific joint derangements
0.763 0.237 0.000
S10-S19 Injuries to the neck
0.762 0.238 0.000
S70-S79 Injuries to the hip and thigh
0.761 0.239 0.000
S06.5 Traumatic subdural haemorrhage
0.761 0.239 0.000
D45 Polycythaemia vera
0.758 0.242 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.756 0.244 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.755 0.245 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.754 0.246 0.000
D64.8 Other specified anaemias
0.754 0.246 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.754 0.246 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.753 0.246 0.000
C79.2 Secondary malignant neoplasm of skin
0.753 0.247 0.000
C78.2 Secondary malignant neoplasm of pleura
0.752 0.248 0.000
C77.1 Intrathoracic lymph nodes
0.749 0.251 0.000
Z48.8 Other specified surgical follow-up care
0.746 0.254 0.000
C18.0 Caecum
0.746 0.254 0.000
D50.8 Other iron deficiency anaemias
0.746 0.254 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.745 0.255 0.000
Chapter VII Diseases of the eye and adnexa
0.745 0.255 0.000
C77.2 Intra-abdominal lymph nodes
0.744 0.256 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.743 0.257 0.000
C64-C68 Malignant neoplasms of urinary tract
0.742 0.258 0.000
N99-N99 Other disorders of the genitourinary system
0.742 0.258 0.000
C16.0 Cardia
0.742 0.258 0.000
S40 Superficial injury of shoulder and upper arm
0.742 0.258 0.000
S50-S59 Injuries to the elbow and forearm
0.741 0.259 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.740 0.260 0.000
T66-T78 Other and unspecified effects of external causes
0.740 0.260 0.000
M87 Osteonecrosis
0.740 0.260 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.738 0.262 0.000
S90-S99 Injuries to the ankle and foot
0.737 0.263 0.000
S80 Superficial injury of lower leg
0.733 0.267 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.733 0.267 0.000
W19 Unspecified fall
0.733 0.267 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.732 0.268 0.000
Z51.4 Preparatory care for treatment, not elsewhere classified
0.732 0.268 0.000
Z45.8 Adjustment and management of other implanted devices
0.732 0.268 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.731 0.269 0.000
J09-J18 Influenza and pneumonia
0.729 0.271 0.000
C34 Malignant neoplasm of bronchus and lung
0.727 0.273 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.727 0.273 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.726 0.274 0.000
N60-N64 Disorders of breast
0.724 0.276 0.000
H65-H75 Diseases of middle ear and mastoid
0.724 0.276 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.723 0.277 0.000
C10 Malignant neoplasm of oropharynx
0.722 0.278 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.722 0.278 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.722 0.278 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.722 0.278 0.000
M60-M63 Disorders of muscles
0.722 0.278 0.000
F30-F39 Mood [affective] disorders
0.721 0.279 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.721 0.279 0.000
M23 Internal derangement of knee
0.719 0.281 0.000
N40-N51 Diseases of male genital organs
0.719 0.281 0.000
Z08.7 Follow-up examination after combined treatment for malignant neoplasm
0.718 0.282 0.000
S06.2 Diffuse brain injury
0.718 0.282 0.000
T91 Sequelae of injuries of neck and trunk
0.718 0.282 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.717 0.283 0.000
C21 Malignant neoplasm of anus and anal canal
0.717 0.283 0.000
C17 Malignant neoplasm of small intestine
0.717 0.283 0.000
C23 Malignant neoplasm of gallbladder
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
T98 Sequelae of other and unspecified effects of external causes
0.717 0.283 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.716 0.284 0.000
Z51.6 Desensitisation to allergens
0.716 0.284 0.000
J30-J39 Other diseases of upper respiratory tract
0.716 0.284 0.000
C18.8 Overlapping lesion of colon
0.715 0.285 0.000
C18.1 Appendix
0.715 0.285 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.715 0.285 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.715 0.285 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.715 0.285 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.715 0.285 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.715 0.285 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.715 0.285 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.715 0.285 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.715 0.285 0.000
T36 Poisoning by systemic antibiotics
0.715 0.285 0.000
T90 Sequelae of injuries of head
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.714 0.286 0.000
C15.8 Overlapping lesion of oesophagus
0.714 0.286 0.000
C15.3 Upper third of oesophagus
0.714 0.286 0.000
C15.2 Abdominal part of oesophagus
0.714 0.286 0.000
C15.1 Thoracic part of oesophagus
0.714 0.286 0.000
C15.0 Cervical part of oesophagus
0.714 0.286 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
S27 Injury of other and unspecified intrathoracic organs
0.711 0.289 0.000
F60-F69 Disorders of adult personality and behaviour
0.711 0.289 0.000
M40-M43 Deforming dorsopathies
0.711 0.289 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.711 0.289 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.707 0.293 0.000
N25-N29 Other disorders of kidney and ureter
0.704 0.296 0.000
Z49 Care involving dialysis
0.704 0.296 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.704 0.296 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.703 0.297 0.000
M80-M85 Disorders of bone density and structure
0.703 0.297 0.000
M91-M94 Chondropathies
0.703 0.297 0.000
T51 Toxic effect of alcohol
0.702 0.297 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.702 0.298 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.702 0.298 0.000
T39.4 Antirheumatics, not elsewhere classified
0.702 0.298 0.000
T39.2 Pyrazolone derivatives
0.702 0.298 0.000
T39.0 Salicylates
0.700 0.300 0.000
S29.9 Unspecified injury of thorax
0.700 0.300 0.000
S82.3 Fracture of lower end of tibia
0.700 0.300 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.700 0.300 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.700 0.300 0.000
F99-F99 Unspecified mental disorder
0.699 0.300 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.699 0.300 0.000
F70-F79 Mental retardation
0.699 0.300 0.000
S06.3 Focal brain injury
0.698 0.302 0.000
S08 Traumatic amputation of part of head
0.694 0.306 0.000
S07 Crushing injury of head
0.694 0.306 0.000
S05 Injury of eye and orbit
0.694 0.306 0.000
S04 Injury of cranial nerves
0.694 0.306 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.694 0.306 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.694 0.306 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.694 0.306 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.693 0.307 0.000
Z52 Donors of organs and tissues
0.692 0.308 0.000
C16.9 Stomach, unspecified
0.692 0.308 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.692 0.308 0.000
E20-E35 Disorders of other endocrine glands
0.691 0.309 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.690 0.310 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.690 0.310 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.690 0.310 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.690 0.310 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.690 0.310 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.690 0.310 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.690 0.310 0.000
F11 Mental and behavioural disorders due to use of opioids
0.690 0.310 0.000
Z45.2 Adjustment and management of vascular access device
0.689 0.311 0.000
S06.0 Concussion
0.689 0.311 0.000
H81 Disorders of vestibular function
0.688 0.312 0.000
N20-N23 Urolithiasis
0.687 0.313 0.000
Z42.1 Follow-up care involving plastic surgery of breast
0.687 0.313 0.000
F10.9 Unspecified mental and behavioural disorder
0.687 0.313 0.000
F10.8 Other mental and behavioural disorders
0.687 0.313 0.000
F10.7 Residual and late-onset psychotic disorder
0.687 0.313 0.000
F10.6 Amnesic syndrome
0.687 0.313 0.000
F10.5 Psychotic disorder
0.687 0.313 0.000
F10.4 Withdrawal state with delirium
0.687 0.313 0.000
N50 Other disorders of male genital organs
0.686 0.314 0.000
C77.8 Lymph nodes of multiple regions
0.685 0.314 0.000
W20-W49 Exposure to inanimate mechanical forces
0.685 0.315 0.000
Z75 Problems related to medical facilities and other health care
0.684 0.315 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.684 0.316 0.000
S20 Superficial injury of thorax
0.684 0.316 0.000
J18 Pneumonia, organism unspecified
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.682 0.318 0.000
M25 Other joint disorders, not elsewhere classified
0.682 0.318 0.000
S02 Fracture of skull and facial bones
0.680 0.320 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.680 0.320 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000
M35 Other systemic involvement of connective tissue
0.679 0.321 0.000
M23.3 Other meniscus derangements
0.678 0.322 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.678 0.322 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.678 0.322 0.000
T79-T79 Certain early complications of trauma
0.676 0.323 0.000
N61 Inflammatory disorders of breast
0.675 0.325 0.000
J18.9 Pneumonia, unspecified
0.675 0.325 0.000
M21 Other acquired deformities of limbs
0.674 0.326 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.674 0.326 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.674 0.326 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.673 0.327 0.000
M24.1 Other articular cartilage disorders
0.673 0.327 0.000
C55 Malignant neoplasm of uterus, part unspecified
0.670 0.330 0.000
M22 Disorders of patella
0.670 0.330 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.668 0.332 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.668 0.332 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.668 0.332 0.000
C51 Malignant neoplasm of vulva
0.667 0.332 0.000
D67 Hereditary factor IX deficiency
0.667 0.332 0.000
D66 Hereditary factor VIII deficiency
0.667 0.332 0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]
0.667 0.332 0.000
J00-J06 Acute upper respiratory infections
0.667 0.333 0.000
H60-H62 Diseases of external ear
0.667 0.333 0.000
N17-N19 Renal failure
0.667 0.333 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.667 0.333 0.000
D04 Carcinoma in situ of skin
0.667 0.333 0.000
D75 Other diseases of blood and blood-forming organs
0.667 0.333 0.000
D46 Myelodysplastic syndromes
0.665 0.334 0.000
N42 Other disorders of prostate
0.665 0.335 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.663 0.337 0.000
S01.2 Open wound of nose
0.662 0.338 0.000
S89 Other and unspecified injuries of lower leg
0.662 0.338 0.000
N50.8 Other specified disorders of male genital organs
0.661 0.339 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.660 0.340 0.000
M19.0 Primary arthrosis of other joints
0.660 0.340 0.000
C14 Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
0.660 0.340 0.000
C13 Malignant neoplasm of hypopharynx
0.660 0.340 0.000
C11 Malignant neoplasm of nasopharynx
0.660 0.340 0.000
C08 Malignant neoplasm of other and unspecified major salivary glands
0.660 0.340 0.000
C06 Malignant neoplasm of other and unspecified parts of mouth
0.660 0.340 0.000
C05 Malignant neoplasm of palate
0.660 0.340 0.000
C04 Malignant neoplasm of floor of mouth
0.660 0.340 0.000
C03 Malignant neoplasm of gum
0.660 0.340 0.000
C00 Malignant neoplasm of lip
0.660 0.340 0.000
C12 Malignant neoplasm of pyriform sinus
0.660 0.340 0.000
C07 Malignant neoplasm of parotid gland
0.660 0.340 0.000
C20 Malignant neoplasm of rectum
0.660 0.340 0.000
S48 Traumatic amputation of shoulder and upper arm
0.660 0.340 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.660 0.340 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.660 0.340 0.000
S44 Injury of nerves at shoulder and upper arm level
0.660 0.340 0.000
S41 Open wound of shoulder and upper arm
0.660 0.340 0.000
S47 Crushing injury of shoulder and upper arm
0.660 0.340 0.000
S88 Traumatic amputation of lower leg
0.659 0.341 0.000
S87 Crushing injury of lower leg
0.659 0.341 0.000
S86 Injury of muscle and tendon at lower leg level
0.659 0.341 0.000
S85 Injury of blood vessels at lower leg level
0.659 0.341 0.000
S84 Injury of nerves at lower leg level
0.659 0.341 0.000
M19.94 Arthrosis, unspecified (Hand)
0.659 0.341 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.658 0.342 0.000
Y35-Y36 Legal intervention and operations of war
0.658 0.342 0.000
Y10-Y34 Event of undetermined intent
0.658 0.342 0.000
Y00-Y09 Assault
0.658 0.342 0.000
X85-X99 Assault
0.658 0.342 0.000
X50-X57 Overexertion, travel and privation
0.658 0.342 0.000
X30-X39 Exposure to forces of nature
0.658 0.342 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
X10-X19 Contact with heat and hot substances
0.658 0.342 0.000
X00-X09 Exposure to smoke, fire and flames
0.658 0.342 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.658 0.342 0.000
W75-W84 Other accidental threats to breathing
0.658 0.342 0.000
W65-W74 Accidental drowning and submersion
0.658 0.342 0.000
W50-W64 Exposure to animate mechanical forces
0.658 0.342 0.000
V98-V99 Other and unspecified transport accidents
0.658 0.342 0.000
V95-V97 Air and space transport accidents
0.658 0.342 0.000
V90-V94 Water transport accidents
0.658 0.342 0.000
V70-V79 Bus occupant injured in transport accident
0.658 0.342 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.658 0.342 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.658 0.342 0.000
V40-V49 Car occupant injured in transport accident
0.658 0.342 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.658 0.342 0.000
V01-V09 Pedestrian injured in transport accident
0.658 0.342 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.658 0.342 0.000
H90-H95 Other disorders of ear
0.658 0.342 0.000
V80-V89 Other land transport accidents
0.657 0.343 0.000
C25 Malignant neoplasm of pancreas
0.657 0.343 0.000
T42.4 Benzodiazepines
0.657 0.343 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.657 0.343 0.000
C92 Myeloid leukaemia
0.654 0.346 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.654 0.346 0.000
S26 Injury of heart
0.654 0.346 0.000
S25 Injury of blood vessels of thorax
0.654 0.346 0.000
S24 Injury of nerves and spinal cord at thorax level
0.654 0.346 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.654 0.346 0.000
S21 Open wound of thorax
0.654 0.346 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.654 0.346 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.654 0.346 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.654 0.346 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.654 0.346 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.654 0.346 0.000
Z42.0 Follow-up care involving plastic surgery of head and neck
0.653 0.347 0.000
Z40 Prophylactic surgery
0.653 0.347 0.000
T95 Sequelae of burns, corrosions and frostbite
0.652 0.348 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.652 0.348 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.652 0.348 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.652 0.348 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.651 0.349 0.000
S06.9 Intracranial injury, unspecified
0.650 0.350 0.000
S06.8 Other intracranial injuries
0.650 0.350 0.000
S06.7 Intracranial injury with prolonged coma
0.650 0.350 0.000
S06.4 Epidural haemorrhage
0.650 0.350 0.000
S06.1 Traumatic cerebral oedema
0.650 0.350 0.000
C09 Malignant neoplasm of tonsil
0.650 0.350 0.000
S82.2 Fracture of shaft of tibia
0.649 0.351 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.648 0.352 0.000
M87.9 Osteonecrosis, unspecified
0.648 0.352 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.646 0.353 0.000
T43.9 Psychotropic drug, unspecified
0.646 0.354 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.646 0.354 0.000
T43.6 Psychostimulants with abuse potential
0.646 0.354 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.646 0.354 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.646 0.354 0.000
T44.7 Beta-Adrenoreceeptor antagonists, not elsewhere classified
0.646 0.354 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.646 0.354 0.000
M88 Paget's disease of bone [osteitis deformans]
0.645 0.355 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.645 0.355 0.000
S09.9 Unspecified injury of head
0.645 0.355 0.000
C78.0 Secondary malignant neoplasm of lung
0.645 0.355 0.000
V20-V29 Motorcycle rider injured in transport accident
0.644 0.356 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.644 0.356 0.000
D64.4 Congenital dyserythropoietic anaemia
0.643 0.357 0.000
D64.3 Other sideroblastic anaemias
0.643 0.357 0.000
D64.2 Secondary sideroblastic anaemia due to drugs and toxins
0.643 0.357 0.000
D64.1 Secondary sideroblastic anaemia due to disease
0.643 0.357 0.000
D64.0 Hereditary sideroblastic anaemia
0.643 0.357 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.640 0.360 0.000
Z50.1 Other physical therapy
0.640 0.360 0.000
S42.0 Fracture of clavicle
0.640 0.360 0.000
W19.4 Street and highway
0.640 0.360 0.000
M34 Systemic sclerosis
0.640 0.360 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.639 0.360 0.000
M31 Other necrotising vasculopathies
0.638 0.362 0.000
S42.1 Fracture of scapula
0.638 0.362 0.000
W08 Fall involving other furniture
0.637 0.363 0.000
W10 Fall on and from stairs and steps
0.636 0.364 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.636 0.364 0.000
C57 Malignant neoplasm of other and unspecified female genital organs
0.635 0.364 0.000
C58 Malignant neoplasm of placenta
0.635 0.364 0.000
C52 Malignant neoplasm of vagina
0.635 0.364 0.000
F29 Unspecified nonorganic psychosis
0.635 0.365 0.000
C02.9 Tongue, unspecified
0.635 0.365 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.635 0.365 0.000
M19.98 Arthrosis, unspecified (Other)
0.633 0.367 0.000
C77.4 Inguinal and lower limb lymph nodes
0.633 0.367 0.000
M18 Arthrosis of first carpometacarpal joint
0.632 0.367 0.000
S01.3 Open wound of ear
0.632 0.368 0.000
T92.3 Sequelae of dislocation, sprain and strain of upper limb
0.632 0.368 0.000
M90 Osteopathies in diseases classified elsewhere
0.632 0.368 0.000
C69 Malignant neoplasm of eye and adnexa
0.631 0.369 0.000
M70-M79 Other soft tissue disorders
0.631 0.369 0.000
Z47 Other orthopaedic follow-up care
0.631 0.369 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.630 0.370 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.629 0.370 0.000
S81.8 Open wound of other parts of lower leg
0.629 0.370 0.000
S60-S69 Injuries to the wrist and hand
0.629 0.371 0.000
Z08.1 Follow-up examination after radiotherapy for malignant neoplasm
0.628 0.372 0.000
Z43.9 Attention to unspecified artificial opening
0.628 0.372 0.000
Z43.8 Attention to other artificial openings
0.628 0.372 0.000
Z43.7 Attention to artificial vagina
0.628 0.372 0.000
Z43.5 Attention to cyctostomy
0.628 0.372 0.000
Z43.4 Attention to other artificial openings of digestive tract
0.628 0.372 0.000
Z43.0 Attention to tracheostomy
0.628 0.372 0.000
C53 Malignant neoplasm of cervix uteri
0.628 0.372 0.000
S82.8 Fractures of other parts of lower leg
0.628 0.372 0.000
D47.4 Osteomyelofibrosis
0.627 0.373 0.000
Y60.0 During surgical operation
0.627 0.373 0.000
T93 Sequelae of injuries of lower limb
0.627 0.373 0.000
M15 Polyarthrosis
0.626 0.374 0.000
S81.9 Open wound of lower leg, part unspecified
0.626 0.374 0.000
E23 Hypofunction and other disorders of pituitary gland
0.626 0.374 0.000
C77.5 Intrapelvic lymph nodes
0.625 0.375 0.000
M86 Osteomyelitis
0.625 0.375 0.000
C34.3 Lower lobe, bronchus or lung
0.625 0.375 0.000
N30-N39 Other diseases of urinary system
0.624 0.376 0.000
D09 Carcinoma in situ of other and unspecified sites
0.624 0.376 0.000
C16.8 Overlapping lesion of stomach
0.624 0.376 0.000
C16.6 Greater curvature of stomach, unspecified
0.624 0.376 0.000
C16.5 Lesser curvature of stomach, unspecified
0.624 0.376 0.000
C16.4 Pylorus
0.624 0.376 0.000
C16.3 Pyloric antrum
0.624 0.376 0.000
C16.2 Body of stomach
0.624 0.376 0.000
C16.1 Fundus of stomach
0.624 0.376 0.000
C67 Malignant neoplasm of bladder
0.624 0.376 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.624 0.376 0.000
W06 Fall involving bed
0.624 0.376 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.624 0.376 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.623 0.377 0.000
D68.2 Hereditary deficiency of other clotting factors
0.622 0.377 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.622 0.378 0.000
M33 Dermatopolymyositis
0.622 0.378 0.000
M32 Systemic lupus erythematosus
0.622 0.378 0.000
M30 Polyarteritis nodosa and related conditions
0.622 0.378 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.621 0.379 0.000
T51.0 Ethanol
0.620 0.380 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.620 0.380 0.000
T43.2 Other and unspecified antidepressants
0.619 0.381 0.000
C34.9 Bronchus or lung, unspecified
0.618 0.382 0.000
C22.1 Intrahepatic bile duct carcinoma
0.618 0.382 0.000
S01.7 Multiple open wounds of head
0.618 0.382 0.000
S01.4 Open wound of cheek and temporomandibular area
0.618 0.382 0.000
Z72 Problems related to lifestyle
0.618 0.382 0.000
D53 Other nutritional anaemias
0.616 0.384 0.000
F23 Acute and transient psychotic disorders
0.616 0.384 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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