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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118068306
log Bayes Factor = 14.8013
Chromosome 3   position 14,273,131  (GRCh37) Explore rs118068306 on Ensembl!
Variant rs118068306 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
M70-M79 Other soft tissue disorders
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I30-I52 Other forms of heart disease
0.999 0.001 0.000
M75 Shoulder lesions
0.999 0.001 0.000
M75.4 Impingement syndrome of shoulder
0.998 0.002 0.000
G40-G47 Episodic and paroxysmal disorders
0.998 0.002 0.000
G47 Sleep disorders
0.996 0.004 0.000
G47.3 Sleep apnoea
0.994 0.006 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.993 0.007 0.000
M15-M19 Arthrosis
0.992 0.008 0.000
I44 Atrioventricular and left bundle-branch block
0.991 0.009 0.000
C44 Other malignant neoplasms of skin
0.985 0.015 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.982 0.018 0.000
I44.7 Left bundle-branch block, unspecified
0.981 0.019 0.000
Chapter II Neoplasms
0.979 0.021 0.000
Chapter XX External causes of morbidity and mortality
0.973 0.027 0.000
C44.6 Skin of upper limb, including shoulder
0.973 0.027 0.000
C44.7 Skin of lower limb, including hip
0.973 0.027 0.000
M19 Other arthrosis
0.969 0.031 0.000
I51 Complications and ill-defined descriptions of heart disease
0.964 0.036 0.000
I47 Paroxysmal tachycardia
0.963 0.037 0.000
M17 Gonarthrosis [arthrosis of knee]
0.955 0.045 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.948 0.052 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.946 0.054 0.000
I47.1 Supraventricular tachycardia
0.946 0.054 0.000
M65-M68 Disorders of synovium and tendon
0.941 0.059 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.932 0.068 0.000
Chapter X Diseases of the respiratory system
0.927 0.073 0.000
M17.9 Gonarthrosis, unspecified
0.927 0.073 0.000
Chapter I Certain infectious and parasitic diseases
0.925 0.075 0.000
M19.0 Primary arthrosis of other joints
0.921 0.079 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.918 0.082 0.000
G20-G26 Extrapyramidal and movement disorders
0.916 0.084 0.000
I95 Hypotension
0.913 0.087 0.000
I51.7 Cardiomegaly
0.911 0.089 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.907 0.093 0.000
T81 Complications of procedures, not elsewhere classified
0.907 0.093 0.000
M75.3 Calcific tendinitis of shoulder
0.902 0.098 0.000
G90-G99 Other disorders of the nervous system
0.899 0.101 0.000
Chapter V Mental and behavioural disorders
0.894 0.106 0.000
M45-M49 Spondylopathies
0.890 0.110 0.000
L82 Seborrhoeic keratosis
0.888 0.112 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.884 0.116 0.000
I95.1 Orthostatic hypotension
0.882 0.118 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.878 0.122 0.000
G40 Epilepsy
0.877 0.122 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.876 0.124 0.000
M19.9 Arthrosis, unspecified
0.874 0.126 0.000
C44.5 Skin of trunk
0.873 0.127 0.000
S40-S49 Injuries to the shoulder and upper arm
0.872 0.128 0.000
B95-B98 Bacterial, viral and other infectious agents
0.868 0.132 0.000
J09-J18 Influenza and pneumonia
0.865 0.135 0.000
I31 Other diseases of pericardium
0.863 0.137 0.000
I20-I25 Ischaemic heart diseases
0.858 0.142 0.000
B35-B49 Mycoses
0.853 0.147 0.000
G20 Parkinson's disease
0.852 0.148 0.000
I34 Nonrheumatic mitral valve disorders
0.850 0.150 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.846 0.154 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.844 0.156 0.000
Chapter VII Diseases of the eye and adnexa
0.842 0.158 0.000
M75.5 Bursitis of shoulder
0.841 0.159 0.000
X60-X84 Intentional self-harm
0.839 0.161 0.000
M65 Synovitis and tenosynovitis
0.839 0.161 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.836 0.164 0.000
Chapter XIV Diseases of the genitourinary system
0.835 0.165 0.000
G30-G32 Other degenerative diseases of the nervous system
0.833 0.167 0.000
M67 Other disorders of synovium and tendon
0.832 0.168 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.830 0.170 0.000
T66-T78 Other and unspecified effects of external causes
0.830 0.170 0.000
J90-J94 Other diseases of pleura
0.829 0.171 0.000
I20 Angina pectoris
0.827 0.173 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.826 0.174 0.000
M75.0 Adhesive capsulitis of shoulder
0.826 0.174 0.000
C44.1 Skin of eyelid, including canthus
0.826 0.174 0.000
I44.2 Atrioventricular block, complete
0.816 0.184 0.000
M05-M14 Inflammatory polyarthropathies
0.815 0.185 0.000
I44.1 Atrioventricular block, second degree
0.810 0.190 0.000
Chapter XXII Codes for special purposes
0.810 0.190 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.808 0.192 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.806 0.194 0.000
M17.1 Other primary gonarthrosis
0.799 0.201 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.798 0.202 0.000
J95-J99 Other diseases of the respiratory system
0.797 0.203 0.000
I20.8 Other forms of angina pectoris
0.797 0.203 0.000
G47.8 Other sleep disorders
0.794 0.206 0.000
S90-S99 Injuries to the ankle and foot
0.790 0.210 0.000
I38 Endocarditis, valve unspecified
0.788 0.212 0.000
Chapter VIII Diseases of the ear and mastoid process
0.788 0.212 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.787 0.213 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.786 0.214 0.000
J18 Pneumonia, organism unspecified
0.786 0.214 0.000
M20-M25 Other joint disorders
0.783 0.217 0.000
M47 Spondylosis
0.781 0.219 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.780 0.220 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.778 0.222 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.778 0.222 0.000
S70-S79 Injuries to the hip and thigh
0.778 0.222 0.000
I51.4 Myocarditis, unspecified
0.778 0.222 0.000
C44.4 Skin of scalp and neck
0.772 0.228 0.000
T87 Complications peculiar to reattachment and amputation
0.771 0.229 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.770 0.230 0.000
V40-V49 Car occupant injured in transport accident
0.769 0.230 0.000
B37 Candidiasis
0.769 0.231 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.768 0.232 0.000
G70-G73 Diseases of myoneural junction and muscle
0.767 0.233 0.000
S80-S89 Injuries to the knee and lower leg
0.767 0.233 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.766 0.234 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.765 0.235 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.763 0.237 0.000
I34.1 Mitral (valve) prolapse
0.763 0.237 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.762 0.238 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.762 0.238 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.760 0.240 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.758 0.242 0.000
I05-I09 Chronic rheumatic heart diseases
0.758 0.242 0.000
M91-M94 Chondropathies
0.757 0.243 0.000
H52 Disorders of refraction and accommodation
0.757 0.243 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.756 0.244 0.000
I51.8 Other ill-defined heart diseases
0.754 0.246 0.000
M67.8 Other specified disorders of synovium and tendon
0.753 0.247 0.000
C44.0 Skin of lip
0.752 0.248 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.752 0.248 0.000
G43 Migraine
0.751 0.248 0.000
G47.9 Sleep disorder, unspecified
0.751 0.249 0.000
F30-F39 Mood [affective] disorders
0.751 0.249 0.000
M47.9 Spondylosis, unspecified
0.750 0.250 0.000
C64-C68 Malignant neoplasms of urinary tract
0.749 0.250 0.000
L81 Other disorders of pigmentation
0.748 0.252 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.747 0.253 0.000
M40-M43 Deforming dorsopathies
0.746 0.254 0.000
I84 Haemorrhoids
0.745 0.255 0.000
L60-L75 Disorders of skin appendages
0.745 0.255 0.000
J92 Pleural plaque
0.745 0.255 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.744 0.256 0.000
T81.9 Unspecified complication of procedure
0.741 0.258 0.000
N40-N51 Diseases of male genital organs
0.741 0.259 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.739 0.261 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.739 0.261 0.000
G93 Other disorders of brain
0.738 0.261 0.000
I20.0 Unstable angina
0.737 0.263 0.000
T82.3 Mechanical complication of other vascular grafts
0.735 0.265 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.735 0.265 0.000
V10-V19 Pedal cyclist injured in transport accident
0.734 0.266 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.734 0.266 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.733 0.267 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.732 0.267 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.732 0.267 0.000
Y86 Sequelae of other accidents
0.732 0.268 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.729 0.270 0.000
G40.9 Epilepsy, unspecified
0.728 0.272 0.000
I60-I69 Cerebrovascular diseases
0.727 0.273 0.000
I84.8 Unspecified haemorrhoids with other complications
0.727 0.273 0.000
I31.9 Disease of pericardium, unspecified
0.726 0.274 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.726 0.274 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.724 0.276 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.724 0.276 0.000
I45 Other conduction disorders
0.724 0.276 0.000
N60-N64 Disorders of breast
0.723 0.277 0.000
I51.9 Heart disease, unspecified
0.722 0.278 0.000
C43 Malignant melanoma of skin
0.722 0.278 0.000
L20-L30 Dermatitis and eczema
0.722 0.278 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.721 0.279 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.720 0.280 0.000
G95 Other diseases of spinal cord
0.719 0.280 0.000
T90 Sequelae of injuries of head
0.718 0.282 0.000
V80-V89 Other land transport accidents
0.718 0.282 0.000
J18.9 Pneumonia, unspecified
0.718 0.282 0.000
G44 Other headache syndromes
0.718 0.282 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.718 0.282 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M50-M54 Other dorsopathies
0.717 0.283 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.717 0.283 0.000
T79-T79 Certain early complications of trauma
0.717 0.283 0.000
M76 Enthesopathies of lower limb, excluding foot
0.716 0.283 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.716 0.283 0.000
M71 Other bursopathies
0.716 0.283 0.000
T33-T35 Frostbite
0.716 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.283 0.000
S10-S19 Injuries to the neck
0.716 0.283 0.000
M75.8 Other shoulder lesions
0.716 0.284 0.000
M75.9 Shoulder lesion, unspecified
0.716 0.284 0.000
M75.2 Bicipital tendinitis
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.716 0.284 0.000
I48 Atrial fibrillation and flutter
0.716 0.284 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.716 0.284 0.000
I41 Myocarditis in diseases classified elsewhere
0.716 0.284 0.000
I40 Acute myocarditis
0.716 0.284 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.716 0.284 0.000
I37 Pulmonary valve disorders
0.716 0.284 0.000
I36 Nonrheumatic tricuspid valve disorders
0.716 0.284 0.000
I32 Pericarditis in diseases classified elsewhere
0.716 0.284 0.000
I30 Acute pericarditis
0.716 0.284 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.715 0.284 0.000
G41 Status epilepticus
0.715 0.284 0.000
S40 Superficial injury of shoulder and upper arm
0.715 0.285 0.000
G47.4 Narcolepsy and cataplexy
0.714 0.286 0.000
G47.2 Disorders of the sleep-wake schedule
0.714 0.286 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.714 0.286 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.714 0.286 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.714 0.286 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.713 0.287 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.713 0.287 0.000
T86 Failure and rejection of transplanted organs and tissues
0.712 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.712 0.288 0.000
M15 Polyarthrosis
0.711 0.288 0.000
I44.6 Other and unspecified fascicular block
0.711 0.289 0.000
I44.5 Left posterior fascicular block
0.711 0.289 0.000
I44.4 Left anterior fascicular block
0.711 0.289 0.000
I44.3 Other and unspecified atrioventricular block
0.711 0.289 0.000
I95.2 Hypotension due to drugs
0.710 0.290 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.709 0.291 0.000
I10-I15 Hypertensive diseases
0.708 0.292 0.000
T78 Adverse effects, not elsewhere classified
0.708 0.292 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.707 0.293 0.000
H49 Paralytic strabismus
0.707 0.293 0.000
J98 Other respiratory disorders
0.707 0.293 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.707 0.293 0.000
C44.8 Overlapping lesion of skin
0.707 0.293 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.704 0.296 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.703 0.297 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.702 0.298 0.000
I33 Acute and subacute endocarditis
0.700 0.300 0.000
T43.2 Other and unspecified antidepressants
0.700 0.300 0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system
0.700 0.300 0.000
Y83.6 Removal of other organ (partial) (total)
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.698 0.302 0.000
Y35-Y36 Legal intervention and operations of war
0.698 0.302 0.000
Y10-Y34 Event of undetermined intent
0.698 0.302 0.000
Y00-Y09 Assault
0.698 0.302 0.000
X85-X99 Assault
0.698 0.302 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.698 0.302 0.000
X50-X57 Overexertion, travel and privation
0.698 0.302 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.698 0.302 0.000
X30-X39 Exposure to forces of nature
0.698 0.302 0.000
X20-X29 Contact with venomous animals and plants
0.698 0.302 0.000
X10-X19 Contact with heat and hot substances
0.698 0.302 0.000
X00-X09 Exposure to smoke, fire and flames
0.698 0.302 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.698 0.302 0.000
W75-W84 Other accidental threats to breathing
0.698 0.302 0.000
W65-W74 Accidental drowning and submersion
0.698 0.302 0.000
W50-W64 Exposure to animate mechanical forces
0.698 0.302 0.000
V98-V99 Other and unspecified transport accidents
0.698 0.302 0.000
V95-V97 Air and space transport accidents
0.698 0.302 0.000
V90-V94 Water transport accidents
0.698 0.302 0.000
V70-V79 Bus occupant injured in transport accident
0.698 0.302 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.698 0.302 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.698 0.302 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.698 0.302 0.000
V01-V09 Pedestrian injured in transport accident
0.698 0.302 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.697 0.303 0.000
M19.8 Other specified arthrosis
0.695 0.305 0.000
M19.2 Other secondary arthrosis
0.695 0.305 0.000
M19.1 Posttraumatic arthrosis of other joints
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.694 0.306 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.694 0.306 0.000
B25-B34 Other viral diseases
0.693 0.306 0.000
B44 Aspergillosis
0.693 0.307 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.691 0.308 0.000
I51.6 Cardiovascular disease, unspecified
0.691 0.309 0.000
I51.5 Myocardial degeneration
0.691 0.309 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.691 0.309 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.691 0.309 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.691 0.309 0.000
I51.0 Cardiac septal defect, acquired
0.691 0.309 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.691 0.309 0.000
I47.0 Reentry ventricular arrhythmia
0.691 0.309 0.000
M10 Gout
0.690 0.310 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.689 0.311 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
W00-W19 Falls
0.688 0.312 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.688 0.312 0.000
L93 Lupus erythematosus
0.688 0.312 0.000
H52.1 Myopia
0.687 0.313 0.000
I31.3 Pericardial effusion (noninflammatory)
0.687 0.313 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.687 0.313 0.000
F32 Depressive episode
0.686 0.314 0.000
W20-W49 Exposure to inanimate mechanical forces
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.686 0.314 0.000
M46 Other inflammatory spondylopathies
0.685 0.315 0.000
M17.5 Other secondary gonarthrosis
0.685 0.315 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.685 0.315 0.000
M17.3 Other posttraumatic gonarthrosis
0.685 0.315 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.685 0.315 0.000
L84 Corns and callosities
0.684 0.316 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.684 0.316 0.000
B37.0 Candidal stomatitis
0.682 0.317 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.682 0.318 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.682 0.318 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.682 0.318 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.681 0.319 0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified
0.680 0.320 0.000
I99 Other and unspecified disorders of circulatory system
0.680 0.320 0.000
J11 Influenza, virus not identified
0.679 0.321 0.000
L10-L14 Bullous disorders
0.678 0.322 0.000
J93 Pneumothorax
0.678 0.322 0.000
M45 Ankylosing spondylitis
0.677 0.322 0.000
G91 Hydrocephalus
0.677 0.323 0.000
M19.98 Arthrosis, unspecified (Other)
0.677 0.323 0.000
J10 Influenza due to identified influenza virus
0.675 0.325 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.675 0.325 0.000
M66 Spontaneous rupture of synovium and tendon
0.675 0.325 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.674 0.326 0.000
M25 Other joint disorders, not elsewhere classified
0.673 0.327 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.672 0.328 0.000
Y83.1 Surgical operation with implant of artificial internal device
0.672 0.328 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.671 0.329 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.670 0.330 0.000
L50-L54 Urticaria and erythema
0.670 0.330 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.669 0.330 0.000
G25 Other extrapyramidal and movement disorders
0.668 0.331 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.668 0.332 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.668 0.332 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.668 0.332 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.668 0.332 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.668 0.332 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.668 0.332 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.668 0.332 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.668 0.332 0.000
T36 Poisoning by systemic antibiotics
0.668 0.332 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.668 0.332 0.000
M19.04 Primary arthrosis of other joints (Hand)
0.668 0.332 0.000
I42 Cardiomyopathy
0.668 0.332 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.668 0.332 0.000
I84.6 Residual haemorrhoidal skin tags
0.667 0.333 0.000
M80-M85 Disorders of bone density and structure
0.667 0.333 0.000
S70 Superficial injury of hip and thigh
0.666 0.334 0.000
D00-D09 In situ neoplasms
0.665 0.335 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.665 0.335 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.664 0.336 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.663 0.336 0.000
M79.0 Rheumatism, unspecified
0.663 0.337 0.000
B99-B99 Other infectious diseases
0.663 0.337 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.663 0.337 0.000
B65-B83 Helminthiases
0.663 0.337 0.000
B50-B64 Protozoal diseases
0.663 0.337 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.663 0.337 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.663 0.337 0.000
A80-A89 Viral infections of the central nervous system
0.663 0.337 0.000
A75-A79 Rickettsioses
0.663 0.337 0.000
A70-A74 Other diseases caused by chlamydiae
0.663 0.337 0.000
A65-A69 Other spirochaetal diseases
0.663 0.337 0.000
A20-A28 Certain zoonotic bacterial diseases
0.663 0.337 0.000
A15-A19 Tuberculosis
0.663 0.337 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.663 0.337 0.000
N47 Redundant prepuce, phimosis and paraphimosis
0.663 0.337 0.000
M77 Other enthesopathies
0.662 0.338 0.000
S50-S59 Injuries to the elbow and forearm
0.662 0.338 0.000
M86-M90 Other osteopathies
0.662 0.338 0.000
N20-N23 Urolithiasis
0.661 0.339 0.000
C51-C58 Malignant neoplasms of female genital organs
0.661 0.339 0.000
M19.08 Primary arthrosis of other joints (Other)
0.660 0.340 0.000
M19.06 Primary arthrosis of other joints-Lower leg
0.660 0.340 0.000
M19.05 Primary arthrosis of other joints (Pelvic region and thigh)
0.660 0.340 0.000
M19.03 Primary arthrosis of other joints (Forearm)
0.660 0.340 0.000
M19.02 Primary arthrosis of other joints (Upper arm)
0.660 0.340 0.000
M19.00 Primary arthrosis of other joints (Multiple sites)
0.660 0.340 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.660 0.340 0.000
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft
0.658 0.342 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.658 0.342 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.658 0.342 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.657 0.343 0.000
G24 Dystonia
0.656 0.343 0.000
G23 Other degenerative diseases of basal ganglia
0.656 0.343 0.000
G21 Secondary Parkinsonism
0.656 0.343 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.656 0.343 0.000
G22 Parkinsonism in diseases classified elsewhere
0.656 0.343 0.000
Y84.8 Other medical procedures
0.656 0.344 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.655 0.345 0.000
J81 Pulmonary oedema
0.655 0.345 0.000
I95.8 Other hypotension
0.655 0.345 0.000
I95.0 Idiopathic hypotension
0.655 0.345 0.000
J00-J06 Acute upper respiratory infections
0.653 0.347 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.653 0.347 0.000
Y88 Sequelae of surgical and medical care as external cause
0.653 0.347 0.000
I61 Intracerebral haemorrhage
0.652 0.348 0.000
F99-F99 Unspecified mental disorder
0.651 0.349 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.651 0.349 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.651 0.349 0.000
L94 Other localised connective tissue disorders
0.651 0.349 0.000
L87 Transepidermal elimination disorders
0.651 0.349 0.000
L88 Pyoderma gangrenosum
0.651 0.349 0.000
L86 Keratoderma in diseases classified elsewhere
0.651 0.349 0.000
L83 Acanthosis nigricans
0.651 0.349 0.000
L80 Vitiligo
0.651 0.349 0.000
M72 Fibroblastic disorders
0.651 0.349 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.650 0.350 0.000
I95.9 Hypotension, unspecified
0.650 0.350 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.650 0.350 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.650 0.350 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.650 0.350 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.650 0.350 0.000
L85 Other epidermal thickening
0.650 0.350 0.000
E20-E35 Disorders of other endocrine glands
0.648 0.352 0.000
G30 Alzheimer's disease
0.646 0.354 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.646 0.354 0.000
M16 Coxarthrosis [arthrosis of hip]
0.646 0.354 0.000
T42.4 Benzodiazepines
0.645 0.355 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.644 0.355 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.644 0.355 0.000
G90 Disorders of autonomic nervous system
0.644 0.355 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.644 0.355 0.000
G92 Toxic encephalopathy
0.644 0.355 0.000
G96 Other disorders of central nervous system
0.644 0.356 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.643 0.357 0.000
B15-B19 Viral hepatitis
0.643 0.357 0.000
F60-F69 Disorders of adult personality and behaviour
0.643 0.357 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.642 0.358 0.000
C44.2 Skin of ear and external auricular canal
0.642 0.358 0.000
J92.0 Pleural plaque with presence of asbestos
0.641 0.359 0.000
M21 Other acquired deformities of limbs
0.641 0.359 0.000
S20-S29 Injuries to the thorax
0.641 0.359 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.641 0.359 0.000
F80-F89 Disorders of psychological development
0.641 0.359 0.000
F70-F79 Mental retardation
0.641 0.359 0.000
T92 Sequelae of injuries of upper limb
0.640 0.359 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.640 0.360 0.000
M49 Spondylopathies in diseases classified elsewhere
0.638 0.362 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.636 0.363 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.636 0.364 0.000
C15-C26 Malignant neoplasms of digestive organs
0.636 0.364 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.635 0.365 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.634 0.366 0.000
N10-N16 Renal tubulo-interstitial diseases
0.634 0.366 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.634 0.366 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.634 0.366 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.634 0.366 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.634 0.366 0.000
T82.1 Mechanical complication of cardiac electronic device
0.634 0.366 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.634 0.366 0.000
L81.4 Other melanin hyperpigmentation
0.634 0.366 0.000
I84.3 External thrombosed haemorrhoids
0.634 0.366 0.000
N48 Other disorders of penis
0.634 0.366 0.000
I22 Subsequent myocardial infarction
0.633 0.366 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.632 0.368 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.631 0.369 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.631 0.369 0.000
Y83.8 Other surgical procedures
0.630 0.370 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.629 0.370 0.000
H65-H75 Diseases of middle ear and mastoid
0.629 0.371 0.000
I44.0 Atrioventricular block, first degree
0.629 0.371 0.000
G40.8 Other epilepsy
0.629 0.371 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.629 0.371 0.000
G40.5 Special epileptic syndromes
0.629 0.371 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.629 0.371 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.629 0.371 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.629 0.371 0.000
B37.3 Candidiasis of vulva and vagina
0.629 0.371 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.629 0.371 0.000
J60-J70 Lung diseases due to external agents
0.628 0.371 0.000
H55-H59 Other disorders of eye and adnexa
0.628 0.372 0.000
T83.9 Unspecified complication of genito-urinary prosthetic device, implant and graft
0.628 0.372 0.000
T83.6 Infection and inflammatory reaction due to prosthetic device, implant and graft in genital tract
0.628 0.372 0.000
T83.4 Mechanical complication of other prosthetic devices, implants and grafts in genital tract
0.628 0.372 0.000
T83.3 Mechanical complication of intra-uterine contraceptive device
0.628 0.372 0.000
T83.2 Mechanical complication of graft of urinary organ
0.628 0.372 0.000
B35 Dermatophytosis
0.627 0.373 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.627 0.373 0.000
M48 Other spondylopathies
0.626 0.374 0.000
S48 Traumatic amputation of shoulder and upper arm
0.625 0.374 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.625 0.374 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.625 0.374 0.000
S44 Injury of nerves at shoulder and upper arm level
0.625 0.374 0.000
S41 Open wound of shoulder and upper arm
0.625 0.374 0.000
S47 Crushing injury of shoulder and upper arm
0.625 0.374 0.000
J18.0 Bronchopneumonia, unspecified
0.625 0.375 0.000
H60-H62 Diseases of external ear
0.625 0.375 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.625 0.375 0.000
G43.1 Migraine with aura [classical migraine]
0.625 0.375 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.624 0.376 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.623 0.377 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.623 0.377 0.000
F45 Somatoform disorders
0.623 0.377 0.000
H10-H13 Disorders of conjunctiva
0.623 0.377 0.000
N62 Hypertrophy of breast
0.622 0.378 0.000
J94 Other pleural conditions
0.622 0.378 0.000
H49.0 Third [oculomotor] nerve palsy
0.621 0.379 0.000
J92.9 Pleural plaque without asbestos
0.621 0.379 0.000
S92 Fracture of foot, except ankle
0.620 0.380 0.000
J17 Pneumonia in diseases classified elsewhere
0.620 0.380 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.620 0.380 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.620 0.380 0.000
J12 Viral pneumonia, not elsewhere classified
0.620 0.380 0.000
J14 Pneumonia due to Haemophilus influenzae
0.620 0.380 0.000
J09 Influenza due to certain identified influenza virus
0.620 0.380 0.000
I31.8 Other specified diseases of pericardium
0.618 0.381 0.000
I31.2 Haemopericardium, not elsewhere classified
0.618 0.381 0.000
I31.1 Chronic constrictive pericarditis
0.618 0.381 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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