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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118113273
log Bayes Factor = 22.5923
Chromosome 12   position 128,300,100  (GRCh37) Explore rs118113273 on Ensembl!
Variant rs118113273 is part of Cluster X0040

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I30-I52 Other forms of heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
I20 Angina pectoris
0.998 0.002 0.000
M45-M49 Spondylopathies
0.997 0.003 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.997 0.003 0.000
I20.0 Unstable angina
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.993 0.007 0.000
Z50 Care involving use of rehabilitation procedures
0.991 0.009 0.000
D50-D53 Nutritional anaemias
0.990 0.010 0.000
Z50.1 Other physical therapy
0.990 0.010 0.000
I50 Heart failure
0.989 0.011 0.000
D50 Iron deficiency anaemia
0.988 0.012 0.000
D50.8 Other iron deficiency anaemias
0.986 0.014 0.000
I60-I69 Cerebrovascular diseases
0.983 0.017 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.982 0.018 0.000
M80-M85 Disorders of bone density and structure
0.980 0.020 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.978 0.022 0.000
M47 Spondylosis
0.977 0.023 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.973 0.027 0.000
M20-M25 Other joint disorders
0.973 0.027 0.000
Z53.0 Procedure not carried out because of contraindication
0.971 0.029 0.000
I25 Chronic ischaemic heart disease
0.970 0.030 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.970 0.030 0.000
Z13 Special screening examination for other diseases and disorders
0.969 0.031 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.969 0.031 0.000
S60-S69 Injuries to the wrist and hand
0.967 0.033 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.964 0.036 0.000
M81 Osteoporosis without pathological fracture
0.963 0.037 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.963 0.037 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.963 0.037 0.000
I35 Nonrheumatic aortic valve disorders
0.959 0.041 0.000
I50.1 Left ventricular failure
0.958 0.042 0.000
M48 Other spondylopathies
0.958 0.042 0.000
I31 Other diseases of pericardium
0.957 0.043 0.000
M47.9 Spondylosis, unspecified
0.957 0.043 0.000
M50-M54 Other dorsopathies
0.956 0.044 0.000
I69 Sequelae of cerebrovascular disease
0.956 0.044 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.955 0.045 0.000
Z86 Personal history of certain other diseases
0.954 0.046 0.000
E65-E68 Obesity and other hyperalimentation
0.954 0.046 0.000
Z86.7 Personal history of diseases of the circulatory system
0.954 0.046 0.000
I50.0 Congestive heart failure
0.953 0.047 0.000
M81.9 Osteoporosis, unspecified
0.951 0.049 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.947 0.053 0.000
E66 Obesity
0.941 0.059 0.000
Z01.8 Other specified special examinations
0.934 0.066 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.933 0.067 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.931 0.069 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.930 0.070 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.929 0.071 0.000
E66.8 Other obesity
0.926 0.074 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.923 0.077 0.000
M48.0 Spinal stenosis
0.923 0.077 0.000
G90-G99 Other disorders of the nervous system
0.923 0.077 0.000
I31.3 Pericardial effusion (noninflammatory)
0.921 0.079 0.000
T81 Complications of procedures, not elsewhere classified
0.921 0.079 0.000
G20-G26 Extrapyramidal and movement disorders
0.920 0.080 0.000
I44 Atrioventricular and left bundle-branch block
0.919 0.081 0.000
M54 Dorsalgia
0.919 0.081 0.000
S61 Open wound of wrist and hand
0.915 0.085 0.000
M25 Other joint disorders, not elsewhere classified
0.915 0.085 0.000
I69.3 Sequelae of cerebral infarction
0.911 0.089 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.911 0.089 0.000
I25.2 Old myocardial infarction
0.907 0.093 0.000
I49 Other cardiac arrhythmias
0.906 0.094 0.000
M05-M14 Inflammatory polyarthropathies
0.904 0.096 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.904 0.096 0.000
S50-S59 Injuries to the elbow and forearm
0.889 0.111 0.000
S61.0 Open wound of finger(s) without damage to nail
0.888 0.112 0.000
G35 Multiple sclerosis
0.886 0.114 0.000
Z91.0 Personal history of allergy, other than to drugs and biological substances
0.886 0.114 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.873 0.127 0.000
Y84.0 Cardiac catheterisation
0.870 0.130 0.000
Z45 Adjustment and management of implanted device
0.870 0.130 0.000
Z93 Artificial opening status
0.869 0.131 0.000
Chapter VIII Diseases of the ear and mastoid process
0.867 0.133 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.866 0.134 0.000
M54.5 Low back pain
0.865 0.135 0.000
I42 Cardiomyopathy
0.864 0.136 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.862 0.138 0.000
E20-E35 Disorders of other endocrine glands
0.862 0.138 0.000
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified
0.860 0.140 0.000
M34 Systemic sclerosis
0.859 0.141 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.858 0.142 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.854 0.146 0.000
I77 Other disorders of arteries and arterioles
0.854 0.146 0.000
M13 Other arthritis
0.849 0.151 0.000
Z97 Presence of other devices
0.847 0.153 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.847 0.153 0.000
Chapter VII Diseases of the eye and adnexa
0.846 0.154 0.000
H65-H75 Diseases of middle ear and mastoid
0.842 0.158 0.000
G70-G73 Diseases of myoneural junction and muscle
0.841 0.159 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.841 0.159 0.000
G93 Other disorders of brain
0.839 0.161 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.839 0.161 0.000
E70-E90 Metabolic disorders
0.837 0.163 0.000
M48.06 Spinal stenosis (Lumbar region)
0.836 0.164 0.000
Z01.9 Special examination, unspecified
0.835 0.165 0.000
I67 Other cerebrovascular diseases
0.835 0.165 0.000
W00-W19 Falls
0.835 0.165 0.000
G30-G32 Other degenerative diseases of the nervous system
0.835 0.165 0.000
I25.1 Atherosclerotic heart disease
0.834 0.166 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.834 0.166 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.832 0.168 0.000
M25.5 Pain in joint
0.831 0.169 0.000
G37 Other demyelinating diseases of central nervous system
0.830 0.170 0.000
M54.56 Low back pain (Lumbar region)
0.829 0.171 0.000
W50-W64 Exposure to animate mechanical forces
0.828 0.172 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.826 0.174 0.000
G62 Other polyneuropathies
0.825 0.175 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.823 0.177 0.000
G40-G47 Episodic and paroxysmal disorders
0.822 0.178 0.000
I44.3 Other and unspecified atrioventricular block
0.821 0.179 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.821 0.179 0.000
I44.1 Atrioventricular block, second degree
0.820 0.180 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.820 0.180 0.000
D80-D89 Certain disorders involving the immune mechanism
0.820 0.180 0.000
I22 Subsequent myocardial infarction
0.819 0.181 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.818 0.182 0.000
S70-S79 Injuries to the hip and thigh
0.816 0.184 0.000
S60 Superficial injury of wrist and hand
0.815 0.185 0.000
Z99.1 Dependence on respirator
0.814 0.186 0.000
Z93.1 Gastrostomy status
0.812 0.188 0.000
I74 Arterial embolism and thrombosis
0.811 0.189 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.810 0.190 0.000
I20.8 Other forms of angina pectoris
0.809 0.191 0.000
I33 Acute and subacute endocarditis
0.809 0.191 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.806 0.193 0.000
I72 Other aneurysm
0.804 0.196 0.000
I35.0 Aortic (valve) stenosis
0.803 0.197 0.000
M47.8 Other spondylosis
0.803 0.197 0.000
I70 Atherosclerosis
0.800 0.200 0.000
M48.02 Spinal stenosis (Cervical region)
0.800 0.200 0.000
Y84.8 Other medical procedures
0.799 0.201 0.000
I49.9 Cardiac arrhythmia, unspecified
0.798 0.202 0.000
I35.9 Aortic valve disorder, unspecified
0.797 0.203 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.797 0.203 0.000
Z01.6 Radiological examination, not elsewhere classified
0.796 0.204 0.000
Chapter V Mental and behavioural disorders
0.796 0.204 0.000
D50.9 Iron deficiency anaemia, unspecified
0.795 0.205 0.000
E83 Disorders of mineral metabolism
0.795 0.205 0.000
Z45.0 Adjustment and management of cardiac pacemaker
0.795 0.205 0.000
M51 Other intervertebral disk disorders
0.794 0.206 0.000
M13.9 Arthritis, unspecified
0.793 0.207 0.000
Z51 Other medical care
0.792 0.208 0.000
Z51.2 Other chemotherapy
0.792 0.208 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.790 0.210 0.000
S10-S19 Injuries to the neck
0.788 0.212 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.788 0.212 0.000
I35.8 Other aortic valve disorders
0.788 0.212 0.000
Z91.8 Personal history of other specified risk-factors, not elsewhere classified
0.788 0.212 0.000
M86-M90 Other osteopathies
0.785 0.215 0.000
M30 Polyarteritis nodosa and related conditions
0.783 0.217 0.000
Y84.6 Urinary catheterisation
0.782 0.218 0.000
G25 Other extrapyramidal and movement disorders
0.782 0.218 0.000
E83.1 Disorders of iron metabolism
0.782 0.218 0.000
S51 Open wound of forearm
0.778 0.222 0.000
M25.4 Effusion of joint
0.776 0.224 0.000
I27 Other pulmonary heart diseases
0.775 0.225 0.000
Z92 Personal history of medical treatment
0.774 0.226 0.000
M84 Disorders of continuity of bone
0.773 0.227 0.000
H65 Nonsuppurative otitis media
0.771 0.229 0.000
M21 Other acquired deformities of limbs
0.770 0.230 0.000
I60 Subarachnoid haemorrhage
0.770 0.230 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.770 0.230 0.000
I77.6 Arteritis, unspecified
0.768 0.232 0.000
T86 Failure and rejection of transplanted organs and tissues
0.768 0.232 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.767 0.233 0.000
M22 Disorders of patella
0.766 0.234 0.000
I26 Pulmonary embolism
0.766 0.234 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.765 0.235 0.000
I78 Diseases of capillaries
0.764 0.236 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.763 0.237 0.000
T66-T78 Other and unspecified effects of external causes
0.762 0.238 0.000
I20.9 Angina pectoris, unspecified
0.761 0.239 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.761 0.239 0.000
G62.9 Polyneuropathy, unspecified
0.761 0.239 0.000
M25.8 Other specified joint disorders
0.759 0.241 0.000
G20 Parkinson's disease
0.759 0.241 0.000
M46 Other inflammatory spondylopathies
0.758 0.242 0.000
V20-V29 Motorcycle rider injured in transport accident
0.758 0.242 0.000
T81.9 Unspecified complication of procedure
0.757 0.243 0.000
I61 Intracerebral haemorrhage
0.756 0.244 0.000
Z63 Other problems related to primary support group, including family circumstances
0.755 0.245 0.000
Z57 Occupational exposure to risk-factors
0.755 0.245 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.754 0.246 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.752 0.247 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.752 0.247 0.000
H43-H45 Disorders of vitreous body and globe
0.752 0.248 0.000
M45 Ankylosing spondylitis
0.752 0.248 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.751 0.249 0.000
S90-S99 Injuries to the ankle and foot
0.748 0.252 0.000
G24 Dystonia
0.748 0.252 0.000
M54.9 Dorsalgia, unspecified
0.747 0.253 0.000
M54.4 Lumbago with sciatica
0.747 0.253 0.000
Z97.4 Presence of external hearing-aid
0.746 0.254 0.000
G47 Sleep disorders
0.746 0.254 0.000
D69 Purpura and other haemorrhagic conditions
0.745 0.255 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.744 0.256 0.000
V80-V89 Other land transport accidents
0.743 0.257 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.743 0.257 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.742 0.258 0.000
G37.9 Demyelinating disease of central nervous system, unspecified
0.740 0.260 0.000
G96 Other disorders of central nervous system
0.737 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
I44.0 Atrioventricular block, first degree
0.736 0.264 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.736 0.264 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.736 0.264 0.000
H74 Other disorders of middle ear and mastoid
0.735 0.265 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.735 0.265 0.000
M34.1 CR(E)ST syndrome
0.734 0.266 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.733 0.267 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.733 0.267 0.000
G72 Other myopathies
0.732 0.268 0.000
S40-S49 Injuries to the shoulder and upper arm
0.730 0.270 0.000
M24 Other specific joint derangements
0.730 0.270 0.000
I30 Acute pericarditis
0.727 0.273 0.000
I31.9 Disease of pericardium, unspecified
0.725 0.275 0.000
Z13.9 Special screening examination, unspecified
0.724 0.276 0.000
M40-M43 Deforming dorsopathies
0.724 0.276 0.000
M53 Other dorsopathies, not elsewhere classified
0.723 0.276 0.000
M00-M03 Infectious arthropathies
0.723 0.277 0.000
S62 Fracture at wrist and hand level
0.723 0.277 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.723 0.277 0.000
X60-X84 Intentional self-harm
0.722 0.278 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.722 0.278 0.000
M20 Acquired deformities of fingers and toes
0.722 0.278 0.000
Z12 Special screening examination for neoplasms
0.722 0.278 0.000
G93.3 Postviral fatigue syndrome
0.722 0.278 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.721 0.278 0.000
S61.1 Open wound of finger(s) with damage to nail
0.721 0.279 0.000
I49.3 Ventricular premature depolarisation
0.721 0.279 0.000
Z29 Need for other prophylactic measures
0.720 0.280 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.720 0.280 0.000
I63 Cerebral infarction
0.719 0.281 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.719 0.281 0.000
Y44 Agents primarily affecting blood constituents
0.718 0.282 0.000
I49.4 Other and unspecified premature depolarisation
0.718 0.282 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I36 Nonrheumatic tricuspid valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
G61 Inflammatory polyneuropathy
0.716 0.284 0.000
M35 Other systemic involvement of connective tissue
0.716 0.284 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
W20-W49 Exposure to inanimate mechanical forces
0.715 0.285 0.000
Z43 Attention to artificial openings
0.715 0.285 0.000
M49 Spondylopathies in diseases classified elsewhere
0.715 0.285 0.000
Z44 Fitting and adjustment of external prosthetic device
0.715 0.285 0.000
Q24 Other congenital malformations of heart
0.715 0.285 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.715 0.285 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.714 0.286 0.000
T51 Toxic effect of alcohol
0.714 0.286 0.000
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level
0.714 0.286 0.000
I35.1 Aortic (valve) insufficiency
0.713 0.287 0.000
M25.51 Pain in joint (Shoulder region)
0.713 0.287 0.000
D55-D59 Haemolytic anaemias
0.713 0.287 0.000
M47.1 Other spondylosis with myelopathy
0.713 0.287 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.712 0.288 0.000
Y35-Y36 Legal intervention and operations of war
0.712 0.288 0.000
Y10-Y34 Event of undetermined intent
0.712 0.288 0.000
Y00-Y09 Assault
0.712 0.288 0.000
X85-X99 Assault
0.712 0.288 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.712 0.288 0.000
X30-X39 Exposure to forces of nature
0.712 0.288 0.000
X20-X29 Contact with venomous animals and plants
0.712 0.288 0.000
X10-X19 Contact with heat and hot substances
0.712 0.288 0.000
X00-X09 Exposure to smoke, fire and flames
0.712 0.288 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.712 0.288 0.000
W75-W84 Other accidental threats to breathing
0.712 0.288 0.000
W65-W74 Accidental drowning and submersion
0.712 0.288 0.000
V98-V99 Other and unspecified transport accidents
0.712 0.288 0.000
V95-V97 Air and space transport accidents
0.712 0.288 0.000
V90-V94 Water transport accidents
0.712 0.288 0.000
V70-V79 Bus occupant injured in transport accident
0.712 0.288 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.712 0.288 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.712 0.288 0.000
V40-V49 Car occupant injured in transport accident
0.712 0.288 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.712 0.288 0.000
V01-V09 Pedestrian injured in transport accident
0.712 0.288 0.000
Z50.6 Orthoptic training
0.711 0.289 0.000
Z50.3 Drug rehabilitation
0.711 0.289 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.711 0.289 0.000
W55 Bitten or struck by other mammals
0.711 0.289 0.000
Z54 Convalescence
0.710 0.290 0.000
M14 Arthropathies in other diseases classified elsewhere
0.710 0.290 0.000
D53 Other nutritional anaemias
0.710 0.290 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.709 0.291 0.000
G40 Epilepsy
0.709 0.291 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.709 0.291 0.000
D50.1 Sideropenic dysphagia
0.708 0.292 0.000
E27 Other disorders of adrenal gland
0.708 0.292 0.000
Chapter X Diseases of the respiratory system
0.708 0.292 0.000
I49.5 Sick sinus syndrome
0.708 0.292 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.707 0.293 0.000
M54.3 Sciatica
0.706 0.294 0.000
I67.8 Other specified cerebrovascular diseases
0.706 0.294 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.705 0.295 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.705 0.295 0.000
M65-M68 Disorders of synovium and tendon
0.704 0.295 0.000
Z10 Routine general health check-up of defined subpopulation
0.704 0.296 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.704 0.296 0.000
M83 Adult osteomalacia
0.703 0.297 0.000
M82 Osteoporosis in diseases classified elsewhere
0.703 0.297 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.703 0.297 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.703 0.297 0.000
M07 Psoriatic and enteropathic arthropathies
0.702 0.298 0.000
S20-S29 Injuries to the thorax
0.702 0.298 0.000
I73 Other peripheral vascular diseases
0.702 0.298 0.000
T23 Burn and corrosion of wrist and hand
0.702 0.298 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.701 0.299 0.000
M34.9 Systemic sclerosis, unspecified
0.701 0.299 0.000
I20.1 Angina pectoris with documented spasm
0.701 0.299 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.700 0.299 0.000
M81.98 Osteoporosis, unspecified (Other)
0.700 0.300 0.000
M85 Other disorders of bone density and structure
0.698 0.302 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.698 0.302 0.000
E40-E46 Malnutrition
0.698 0.302 0.000
Z93.6 Other artificial openings of urinary tract status
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.698 0.302 0.000
M33 Dermatopolymyositis
0.698 0.302 0.000
M32 Systemic lupus erythematosus
0.698 0.302 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.698 0.302 0.000
I05-I09 Chronic rheumatic heart diseases
0.697 0.303 0.000
M48.09 Spinal stenosis (Site unspecified)
0.697 0.303 0.000
Z91.5 Personal history of self-harm
0.697 0.303 0.000
Z41 Procedures for purposes other than remedying health state
0.696 0.304 0.000
I25.6 Silent myocardial ischaemia
0.696 0.304 0.000
I25.4 Coronary artery aneurysm
0.696 0.304 0.000
I25.3 Aneurysm of heart
0.696 0.304 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.696 0.304 0.000
T87 Complications peculiar to reattachment and amputation
0.695 0.305 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.695 0.305 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.695 0.305 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.695 0.305 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.695 0.305 0.000
Z13.5 Special screening examination for eye and ear disorders
0.695 0.305 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.695 0.305 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.695 0.305 0.000
Z13.2 Special screening examination for nutritional disorders
0.695 0.305 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.695 0.305 0.000
Q50-Q56 Congenital malformations of genital organs
0.694 0.306 0.000
S65 Injury of blood vessels at wrist and hand level
0.693 0.307 0.000
E22 Hyperfunction of pituitary gland
0.693 0.307 0.000
Z01.7 Laboratory examination
0.691 0.308 0.000
Z01.3 Examination of blood pressure
0.691 0.308 0.000
Z01.2 Dental examination
0.691 0.308 0.000
Z01.1 Examination of ears and hearing
0.691 0.308 0.000
Z01.0 Examination of eyes and vision
0.691 0.308 0.000
M91-M94 Chondropathies
0.691 0.309 0.000
M81.8 Other osteoporosis
0.691 0.309 0.000
M81.6 Localised osteoporosis [Lequesne]
0.691 0.309 0.000
M81.5 Idiopathic osteoporosis
0.691 0.309 0.000
M81.4 Drug-induced osteoporosis
0.691 0.309 0.000
M81.3 Postsurgical malabsorption osteoporosis
0.691 0.309 0.000
M81.2 Osteoporosis of disuse
0.691 0.309 0.000
M81.1 Postoophorectomy osteoporosis
0.691 0.309 0.000
M81.0 Postmenopausal osteoporosis
0.691 0.309 0.000
S60.8 Other superficial injuries of wrist and hand
0.691 0.309 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.690 0.310 0.000
Z84 Family history of other conditions
0.690 0.310 0.000
Z81 Family history of mental and behavioural disorders
0.690 0.310 0.000
I42.2 Other hypertrophic cardiomyopathy
0.687 0.313 0.000
M48.9 Spondylopathy, unspecified
0.686 0.313 0.000
M48.8 Other specified spondylopathies
0.686 0.313 0.000
M48.4 Fatigue fracture of vertebra
0.686 0.313 0.000
M48.3 Traumatic spondylopathy
0.686 0.313 0.000
M48.2 Kissing spine
0.686 0.313 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.686 0.313 0.000
I31.8 Other specified diseases of pericardium
0.686 0.314 0.000
I31.2 Haemopericardium, not elsewhere classified
0.686 0.314 0.000
I31.1 Chronic constrictive pericarditis
0.686 0.314 0.000
I31.0 Chronic adhesive pericarditis
0.686 0.314 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.686 0.314 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.686 0.314 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.686 0.314 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.686 0.314 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.686 0.314 0.000
M47.82 Other spondylosis (Cervical region)
0.686 0.314 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.686 0.314 0.000
T63 Toxic effect of contact with venomous animals
0.686 0.314 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.685 0.315 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.685 0.315 0.000
S64 Injury of nerves at wrist and hand level
0.685 0.315 0.000
G36 Other acute disseminated demyelination
0.685 0.315 0.000
I42.6 Alcoholic cardiomyopathy
0.685 0.315 0.000
E67 Other hyperalimentation
0.684 0.316 0.000
E68 Sequelae of hyperalimentation
0.684 0.316 0.000
E65 Localised adiposity
0.684 0.316 0.000
H25-H28 Disorders of lens
0.684 0.316 0.000
S32 Fracture of lumbar spine and pelvis
0.684 0.316 0.000
I27.2 Other secondary pulmonary hypertension
0.683 0.317 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.683 0.317 0.000
S68 Traumatic amputation of wrist and hand
0.683 0.317 0.000
D51 Vitamin B12 deficiency anaemia
0.682 0.317 0.000
I25.5 Ischaemic cardiomyopathy
0.682 0.318 0.000
M81.97 Osteoporosis, unspecified (Ankle and foot)
0.682 0.318 0.000
M81.96 Osteoporosis, unspecified (Lower leg)
0.682 0.318 0.000
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)
0.682 0.318 0.000
M81.94 Osteoporosis, unspecified (Hand)
0.682 0.318 0.000
M81.93 Osteoporosis, unspecified (Forearm)
0.682 0.318 0.000
M81.92 Osteoporosis, unspecified (Upper arm)
0.682 0.318 0.000
M81.91 Osteoporosis, unspecified (Shoulder region)
0.682 0.318 0.000
M80 Osteoporosis with pathological fracture
0.682 0.318 0.000
Z45.8 Adjustment and management of other implanted devices
0.682 0.318 0.000
G93.0 Cerebral cysts
0.682 0.318 0.000
E00-E07 Disorders of thyroid gland
0.681 0.319 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.681 0.319 0.000
M13.0 Polyarthritis, unspecified
0.681 0.319 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.681 0.319 0.000
S00-S09 Injuries to the head
0.680 0.320 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.679 0.321 0.000
Z53.8 Procedure not carried out for other reasons
0.678 0.322 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.678 0.322 0.000
I42.0 Dilated cardiomyopathy
0.677 0.323 0.000
S50 Superficial injury of forearm
0.677 0.323 0.000
S61.7 Multiple open wounds of wrist and hand
0.676 0.324 0.000
Q60-Q64 Congenital malformations of the urinary system
0.676 0.324 0.000
H43 Disorders of vitreous body
0.676 0.324 0.000
W19 Unspecified fall
0.674 0.326 0.000
E66.1 Drug-induced obesity
0.674 0.326 0.000
E66.0 Obesity due to excess calories
0.674 0.326 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.674 0.326 0.000
S52 Fracture of forearm
0.674 0.326 0.000
H73 Other disorders of tympanic membrane
0.674 0.326 0.000
Q28 Other congenital malformations of circulatory system
0.673 0.327 0.000
T79-T79 Certain early complications of trauma
0.672 0.328 0.000
I33.0 Acute and subacute infective endocarditis
0.672 0.328 0.000
Z57.2 Occupational exposure to dust
0.672 0.328 0.000
Y84.1 Kidney dialysis
0.671 0.329 0.000
Z13.1 Special screening examination for diabetes mellitus
0.671 0.329 0.000
T88.7 Unspecified adverse effect of drug or medicament
0.670 0.330 0.000
M25.50 Pain in joint (Multiple sites)
0.670 0.330 0.000
Z50.2 Alcohol rehabilitation
0.670 0.330 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.670 0.330 0.000
Z91.7 Personal history of female genital mutilation
0.669 0.331 0.000
Z91.4 Personal history of psychological trauma, not elsewhere classified
0.669 0.331 0.000
Z91.3 Personal history of unhealthy sleep-wake schedule
0.669 0.331 0.000
Z91.2 Personal history of poor personal hygiene
0.669 0.331 0.000
Z99.3 Dependence on wheelchair
0.669 0.331 0.000
M25.55 Pain in joint (Pelvic region and thigh)
0.668 0.332 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.667 0.333 0.000
I74.5 Embolism and thrombosis of iliac artery
0.667 0.333 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.667 0.333 0.000
Z93.5 Cystostomy status
0.667 0.333 0.000
M10 Gout
0.667 0.333 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.666 0.334 0.000
Q80-Q89 Other congenital malformations
0.666 0.334 0.000
Q35-Q37 Cleft lip and cleft palate
0.666 0.334 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.666 0.334 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.666 0.334 0.000
E87.2 Acidosis
0.666 0.334 0.000
Y57 Other and unspecified drugs and medicaments
0.666 0.334 0.000
S36 Injury of intra-abdominal organs
0.665 0.335 0.000
E66.9 Obesity, unspecified
0.665 0.335 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.665 0.335 0.000
H69 Other disorders of Eustachian tube
0.665 0.335 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.664 0.336 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.664 0.336 0.000
M25.47 Effusion of joint (Ankle and foot)
0.664 0.336 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.663 0.337 0.000
I49.1 Atrial premature depolarisation
0.662 0.338 0.000
Y84.9 Medical procedure, unspecified
0.662 0.338 0.000
Y84.7 Blood-sampling
0.662 0.338 0.000
Y84.5 Insertion of gastric or duodenal sound
0.662 0.338 0.000
Y84.4 Aspiration of fluid
0.662 0.338 0.000
Y84.3 Shock therapy
0.662 0.338 0.000
M48.08 Spinal stenosis (Sacral and sacrococcygeal region)
0.662 0.338 0.000
M48.05 Spinal stenosis (Thoracolumbar region)
0.662 0.338 0.000
M48.04 Spinal stenosis (Thoracic region)
0.662 0.338 0.000
M48.03 Spinal stenosis (Cervicothoracic region)
0.662 0.338 0.000
M48.01 Spinal stenosis (Occipito-atlanto-axial region)
0.662 0.338 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.662 0.338 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.662 0.338 0.000
G90 Disorders of autonomic nervous system
0.662 0.338 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.662 0.338 0.000
G92 Toxic encephalopathy
0.662 0.338 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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