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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118136136
log Bayes Factor = 2.24787
Chromosome 21   position 35,274,965  (GRCh37) Explore rs118136136 on Ensembl!
Variant rs118136136 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.989 0.011 0.000
M54 Dorsalgia
0.986 0.014 0.000
M70-M79 Other soft tissue disorders
0.984 0.016 0.000
M75 Shoulder lesions
0.977 0.023 0.000
M15-M19 Arthrosis
0.970 0.030 0.000
M54.5 Low back pain
0.968 0.032 0.000
M75.4 Impingement syndrome of shoulder
0.962 0.038 0.000
M54.59 Low back pain (Site unspecified)
0.931 0.069 0.000
M54.9 Dorsalgia, unspecified
0.926 0.074 0.000
M17 Gonarthrosis [arthrosis of knee]
0.896 0.104 0.000
# Top node
0.893 0.107 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.883 0.117 0.000
M65-M68 Disorders of synovium and tendon
0.875 0.125 0.000
M19 Other arthrosis
0.871 0.129 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.869 0.131 0.000
M75.2 Bicipital tendinitis
0.867 0.133 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.850 0.150 0.000
M54.57 Low back pain (Lumbosacral region)
0.847 0.153 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.825 0.175 0.000
M17.9 Gonarthrosis, unspecified
0.822 0.178 0.000
Chapter XI Diseases of the digestive system
0.820 0.180 0.000
E10-E14 Diabetes mellitus
0.817 0.183 0.000
M75.1 Rotator cuff syndrome
0.815 0.185 0.000
M51 Other intervertebral disk disorders
0.796 0.204 0.000
E00-E07 Disorders of thyroid gland
0.795 0.205 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.793 0.206 0.000
K50-K52 Noninfective enteritis and colitis
0.792 0.208 0.000
M16 Coxarthrosis [arthrosis of hip]
0.790 0.210 0.000
M71 Other bursopathies
0.790 0.210 0.000
M67 Other disorders of synovium and tendon
0.789 0.211 0.000
R30-R39 Symptoms and signs involving the urinary system
0.784 0.216 0.000
M54.2 Cervicalgia
0.776 0.224 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.772 0.228 0.000
M20-M25 Other joint disorders
0.770 0.230 0.000
M45-M49 Spondylopathies
0.769 0.231 0.000
M19.9 Arthrosis, unspecified
0.767 0.233 0.000
S50-S59 Injuries to the elbow and forearm
0.762 0.238 0.000
M54.56 Low back pain (Lumbar region)
0.758 0.242 0.000
E11 Non-insulin-dependent diabetes mellitus
0.756 0.244 0.000
M05-M14 Inflammatory polyarthropathies
0.748 0.252 0.000
Chapter XX External causes of morbidity and mortality
0.747 0.253 0.000
M80-M85 Disorders of bone density and structure
0.745 0.255 0.000
M91-M94 Chondropathies
0.744 0.255 0.000
M19.91 Arthrosis, unspecified (Shoulder region)
0.738 0.262 0.000
K51 Ulcerative colitis
0.737 0.263 0.000
M54.1 Radiculopathy
0.735 0.265 0.000
M16.1 Other primary coxarthrosis
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.268 0.000
M67.8 Other specified disorders of synovium and tendon
0.727 0.273 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.724 0.276 0.000
M40-M43 Deforming dorsopathies
0.721 0.278 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.719 0.281 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.718 0.282 0.000
S52 Fracture of forearm
0.716 0.284 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.714 0.286 0.000
Chapter VIII Diseases of the ear and mastoid process
0.713 0.287 0.000
M60-M63 Disorders of muscles
0.713 0.287 0.000
M00-M03 Infectious arthropathies
0.713 0.287 0.000
K35-K38 Diseases of appendix
0.710 0.290 0.000
E20-E35 Disorders of other endocrine glands
0.709 0.291 0.000
M53 Other dorsopathies, not elsewhere classified
0.709 0.291 0.000
M18 Arthrosis of first carpometacarpal joint
0.709 0.291 0.000
M54.8 Other dorsalgia
0.707 0.293 0.000
M54.6 Pain in thoracic spine
0.707 0.293 0.000
M54.4 Lumbago with sciatica
0.707 0.293 0.000
M54.3 Sciatica
0.707 0.293 0.000
M54.0 Panniculitis affecting regions of neck and back
0.707 0.293 0.000
M77 Other enthesopathies
0.706 0.294 0.000
M76 Enthesopathies of lower limb, excluding foot
0.706 0.294 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.706 0.294 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.703 0.297 0.000
M19.0 Primary arthrosis of other joints
0.703 0.297 0.000
M75.8 Other shoulder lesions
0.701 0.299 0.000
M75.9 Shoulder lesion, unspecified
0.701 0.299 0.000
Chapter VI Diseases of the nervous system
0.699 0.301 0.000
E10 Insulin-dependent diabetes mellitus
0.699 0.301 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.698 0.302 0.000
K65-K67 Diseases of peritoneum
0.697 0.303 0.000
M86-M90 Other osteopathies
0.696 0.304 0.000
M15 Polyarthrosis
0.696 0.304 0.000
R39 Other symptoms and signs involving the urinary system
0.696 0.304 0.000
M75.5 Bursitis of shoulder
0.695 0.305 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.694 0.306 0.000
M54.55 Low back pain (Thoracolumbar region)
0.694 0.306 0.000
M54.54 Low back pain-Thoracic
0.694 0.306 0.000
M54.53 Low back pain-Cervicothoracic
0.694 0.306 0.000
M54.52 Low back pain-Cervical
0.694 0.306 0.000
M54.51 Low back pain-Occipit-atl-axl
0.694 0.306 0.000
M54.50 Low back pain (Multiple sites in spine)
0.694 0.306 0.000
R32 Unspecified urinary incontinence
0.693 0.307 0.000
E50-E64 Other nutritional deficiencies
0.692 0.308 0.000
M17.0 Primary gonarthrosis, bilateral
0.692 0.308 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.688 0.312 0.000
M72 Fibroblastic disorders
0.684 0.316 0.000
S52.5 Fracture of lower end of radius
0.682 0.318 0.000
K51.9 Ulcerative colitis, unspecified
0.676 0.324 0.000
E11.9 Without complications
0.675 0.325 0.000
Chapter XXII Codes for special purposes
0.673 0.326 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.671 0.329 0.000
W00-W19 Falls
0.670 0.329 0.000
M17.1 Other primary gonarthrosis
0.668 0.332 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.666 0.334 0.000
K52 Other non-infective gastro-enteritis and colitis
0.666 0.334 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.665 0.335 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.664 0.336 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.664 0.336 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.664 0.336 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.664 0.336 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.664 0.336 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.664 0.336 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.664 0.336 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.664 0.336 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.664 0.336 0.000
R93.8 Abnormal findings on diagnostic imaging of other specified body structures
0.664 0.336 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.662 0.338 0.000
S60-S69 Injuries to the wrist and hand
0.661 0.339 0.000
M75.3 Calcific tendinitis of shoulder
0.660 0.340 0.000
M75.0 Adhesive capsulitis of shoulder
0.659 0.341 0.000
S52.50 Fracture of lower end of radius (closed)
0.657 0.343 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.652 0.347 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.652 0.348 0.000
M71.2 Synovial cyst of popliteal space [Baker]
0.651 0.349 0.000
S40-S49 Injuries to the shoulder and upper arm
0.649 0.351 0.000
T66-T78 Other and unspecified effects of external causes
0.648 0.352 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.648 0.352 0.000
K50 Crohn's disease [regional enteritis]
0.647 0.353 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.646 0.354 0.000
R47-R49 Symptoms and signs involving speech and voice
0.646 0.354 0.000
M25 Other joint disorders, not elsewhere classified
0.644 0.356 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.643 0.357 0.000
R33 Retention of urine
0.643 0.357 0.000
E06 Thyroiditis
0.643 0.357 0.000
M17.5 Other secondary gonarthrosis
0.642 0.357 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.642 0.357 0.000
M17.3 Other posttraumatic gonarthrosis
0.642 0.357 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.642 0.357 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.640 0.360 0.000
S70-S79 Injuries to the hip and thigh
0.638 0.362 0.000
M51.0 Lumbar and other intervertebral disk disorders with myelopathy
0.631 0.369 0.000
M65 Synovitis and tenosynovitis
0.631 0.369 0.000
D80-D89 Certain disorders involving the immune mechanism
0.630 0.370 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.627 0.372 0.000
M66 Spontaneous rupture of synovium and tendon
0.627 0.372 0.000
M54.22 Cervicalgia (Cervical region)
0.625 0.375 0.000
M19.8 Other specified arthrosis
0.624 0.375 0.000
M19.2 Other secondary arthrosis
0.624 0.375 0.000
M19.1 Posttraumatic arthrosis of other joints
0.624 0.375 0.000
E07 Other disorders of thyroid
0.625 0.375 0.000
R35 Polyuria
0.624 0.376 0.000
E05.9 Thyrotoxicosis, unspecified
0.624 0.376 0.000
E40-E46 Malnutrition
0.623 0.377 0.000
K66 Other disorders of peritoneum
0.620 0.380 0.000
Chapter X Diseases of the respiratory system
0.618 0.382 0.000
M50 Cervical disk disorders
0.618 0.382 0.000
M48 Other spondylopathies
0.617 0.383 0.000
E11.4 With neurological complications
0.616 0.384 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.615 0.385 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.609 0.391 0.000
K38 Other diseases of appendix
0.609 0.391 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.608 0.392 0.000
M16.0 Primary coxarthrosis, bilateral
0.608 0.392 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.607 0.393 0.000
M51.2 Other specified intervertebral disk displacement
0.606 0.394 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.604 0.396 0.000
S90-S99 Injuries to the ankle and foot
0.601 0.398 0.000
M22 Disorders of patella
0.601 0.399 0.000
R93.2 Abnormal findings on diagnostic imaging of liver and biliary tract
0.601 0.399 0.000
M31 Other necrotising vasculopathies
0.600 0.400 0.000
M19.94 Arthrosis, unspecified (Hand)
0.600 0.400 0.000
R20 Disturbances of skin sensation
0.599 0.401 0.000
R93.1 Abnormal findings on diagnostic imaging of heart and coronary circulation
0.597 0.403 0.000
E03 Other hypothyroidism
0.596 0.404 0.000
M35 Other systemic involvement of connective tissue
0.594 0.405 0.000
W19 Unspecified fall
0.594 0.406 0.000
K70-K77 Diseases of liver
0.593 0.407 0.000
T79-T79 Certain early complications of trauma
0.592 0.408 0.000
T33-T35 Frostbite
0.592 0.408 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.592 0.408 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.592 0.408 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.592 0.408 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.592 0.408 0.000
T00-T07 Injuries involving multiple body regions
0.592 0.408 0.000
S10-S19 Injuries to the neck
0.592 0.408 0.000
M13 Other arthritis
0.591 0.409 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.588 0.412 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.588 0.412 0.000
M19.93 Arthrosis, unspecified (Forearm)
0.586 0.414 0.000
E13 Other specified diabetes mellitus
0.586 0.414 0.000
E12 Malnutrition-related diabetes mellitus
0.586 0.414 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.586 0.414 0.000
K51.8 Other ulcerative colitis
0.585 0.415 0.000
M45 Ankylosing spondylitis
0.584 0.416 0.000
R39.1 Other difficulties with micturition
0.582 0.418 0.000
R79 Other abnormal findings of blood chemistry
0.582 0.418 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.580 0.420 0.000
M21 Other acquired deformities of limbs
0.579 0.421 0.000
E11.3 With ophthalmic complications
0.578 0.422 0.000
E10.9 Without complications
0.577 0.423 0.000
K52.9 Non-infective gastro-enteritis and colitis, unspecified
0.575 0.425 0.000
R90.8 Other abnormal findings on diagnostic imaging of central nervous system
0.575 0.425 0.000
D50-D53 Nutritional anaemias
0.574 0.426 0.000
E23 Hypofunction and other disorders of pituitary gland
0.572 0.428 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.571 0.429 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.571 0.429 0.000
M51.3 Other specified intervertebral disk degeneration
0.570 0.429 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.570 0.429 0.000
M51.9 Intervertebral disk disorder, unspecified
0.570 0.429 0.000
M51.8 Other specified intervertebral disk disorders
0.570 0.429 0.000
M51.4 Schmorl's nodes
0.570 0.429 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.570 0.430 0.000
E00 Congenital iodine-deficiency syndrome
0.570 0.430 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.570 0.430 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.569 0.431 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.567 0.433 0.000
M16.7 Other secondary coxarthrosis
0.567 0.433 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.567 0.433 0.000
M16.5 Other posttraumatic coxarthrosis
0.567 0.433 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.567 0.433 0.000
M16.3 Other dysplastic coxarthrosis
0.567 0.433 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.567 0.433 0.000
M71.9 Bursopathy, unspecified
0.566 0.433 0.000
M71.8 Other specified bursopathies
0.566 0.433 0.000
M71.5 Other bursitis, not elsewhere classified
0.566 0.433 0.000
M71.4 Calcium deposit in bursa
0.566 0.433 0.000
M71.3 Other bursal cyst
0.566 0.433 0.000
M71.1 Other infective bursitis
0.566 0.433 0.000
M71.0 Abscess of bursa
0.566 0.433 0.000
M67.9 Disorder of synovium and tendon, unspecified
0.566 0.434 0.000
M67.4 Ganglion
0.566 0.434 0.000
M67.3 Transient synovitis
0.566 0.434 0.000
M67.2 Synovial hypertrophy, not elsewhere classified
0.566 0.434 0.000
M67.1 Other contracture of tendon (sheath)
0.566 0.434 0.000
M67.0 Short Achilles tendon (acquired)
0.566 0.434 0.000
M94 Other disorders of cartilage
0.566 0.434 0.000
K66.0 Peritoneal adhesions
0.565 0.435 0.000
R36 Urethral discharge
0.562 0.438 0.000
R34 Anuria and oliguria
0.562 0.438 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.562 0.438 0.000
M80 Osteoporosis with pathological fracture
0.562 0.438 0.000
S52.0 Fracture of upper end of ulna
0.562 0.438 0.000
S80-S89 Injuries to the knee and lower leg
0.561 0.439 0.000
E10.3 With ophthalmic complications
0.561 0.439 0.000
K12 Stomatitis and related lesions
0.561 0.439 0.000
V20-V29 Motorcycle rider injured in transport accident
0.561 0.439 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.560 0.440 0.000
R30 Pain associated with micturition
0.560 0.440 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.558 0.442 0.000
M25.7 Osteophyte
0.558 0.442 0.000
Q00-Q07 Congenital malformations of the nervous system
0.557 0.442 0.000
M54.29 Cervicalgia-Site unspe
0.556 0.444 0.000
M54.28 Cervicalgia-Sacral/sacrococ
0.556 0.444 0.000
M54.27 Cervicalgia-Lumbosacral
0.556 0.444 0.000
M54.26 Cervicalgia-Lumbar
0.556 0.444 0.000
M54.25 Cervicalgia-Thoracolumbar
0.556 0.444 0.000
M54.24 Cervicalgia-Thoracic
0.556 0.444 0.000
M54.23 Cervicalgia (Cervicothoracic region)
0.556 0.444 0.000
M54.21 Cervicalgia (Occipito-atlanto-axial region)
0.556 0.444 0.000
M54.20 Cervicalgia-Mult site
0.556 0.444 0.000
D86 Sarcoidosis
0.555 0.445 0.000
M54.16 Radiculopathy (Lumbar region)
0.555 0.445 0.000
H80-H83 Diseases of inner ear
0.554 0.446 0.000
M06 Other rheumatoid arthritis
0.554 0.446 0.000
R93.7 Abnormal findings on diagnostic imaging of other parts of musculoskeletal system
0.554 0.446 0.000
R93.6 Abnormal findings on diagnostic imaging of limbs
0.554 0.446 0.000
R93.4 Abnormal findings on diagnostic imaging of urinary organs
0.554 0.446 0.000
R93.0 Abnormal findings on diagnostic imaging of skull and head, not elsewhere classified
0.554 0.446 0.000
W19.9 Unspecified place
0.554 0.446 0.000
E65-E68 Obesity and other hyperalimentation
0.553 0.447 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.552 0.448 0.000
M34 Systemic sclerosis
0.552 0.448 0.000
M33 Dermatopolymyositis
0.552 0.448 0.000
M32 Systemic lupus erythematosus
0.552 0.448 0.000
M30 Polyarteritis nodosa and related conditions
0.552 0.448 0.000
M49 Spondylopathies in diseases classified elsewhere
0.551 0.448 0.000
M46 Other inflammatory spondylopathies
0.551 0.448 0.000
M71.26 Synovial cyst of popliteal space [Baker]-Lower Leg
0.551 0.449 0.000
E04 Other non-toxic goitre
0.551 0.449 0.000
M85 Other disorders of bone density and structure
0.551 0.449 0.000
M19.98 Arthrosis, unspecified (Other)
0.550 0.450 0.000
M19.95 Arthrosis, unspecified (Pelvic region and thigh)
0.550 0.450 0.000
M19.92 Arthrosis, unspecified (Upper arm)
0.550 0.450 0.000
E53 Deficiency of other B group vitamins
0.549 0.451 0.000
K50.9 Crohn's disease, unspecified
0.548 0.452 0.000
R23 Other skin changes
0.548 0.452 0.000
E14 Unspecified diabetes mellitus
0.546 0.453 0.000
S59 Other and unspecified injuries of forearm
0.546 0.454 0.000
S58 Traumatic amputation of forearm
0.546 0.454 0.000
S57 Crushing injury of forearm
0.546 0.454 0.000
S56 Injury of muscle and tendon at forearm level
0.546 0.454 0.000
S55 Injury of blood vessels at forearm level
0.546 0.454 0.000
S54 Injury of nerves at forearm level
0.546 0.454 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.546 0.454 0.000
S51 Open wound of forearm
0.546 0.454 0.000
S50 Superficial injury of forearm
0.546 0.454 0.000
K35 Acute appendicitis
0.545 0.455 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.545 0.455 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.544 0.455 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.544 0.456 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.543 0.457 0.000
E11.8 With unspecified complications
0.542 0.458 0.000
E11.7 With multiple complications
0.542 0.458 0.000
E11.6 With other specified complications
0.542 0.458 0.000
E11.5 With peripheral circulatory complications
0.542 0.458 0.000
E11.2 With renal complications
0.542 0.458 0.000
E11.1 With ketoacidosis
0.542 0.458 0.000
E11.0 With coma
0.542 0.458 0.000
G35 Multiple sclerosis
0.541 0.459 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.541 0.459 0.000
S40 Superficial injury of shoulder and upper arm
0.540 0.460 0.000
S20-S29 Injuries to the thorax
0.539 0.461 0.000
M18.1 Other primary arthrosis of first carpometacarpal joint
0.539 0.461 0.000
Chapter VII Diseases of the eye and adnexa
0.538 0.462 0.000
S00-S09 Injuries to the head
0.538 0.462 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.537 0.463 0.000
M14 Arthropathies in other diseases classified elsewhere
0.536 0.464 0.000
M12 Other specific arthropathies
0.536 0.464 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.536 0.464 0.000
M08 Juvenile arthritis
0.536 0.464 0.000
M07 Psoriatic and enteropathic arthropathies
0.536 0.464 0.000
M05 Seropositive rheumatoid arthritis
0.536 0.464 0.000
K38.8 Other specified diseases of appendix
0.536 0.464 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.535 0.465 0.000
Y35-Y36 Legal intervention and operations of war
0.535 0.465 0.000
Y10-Y34 Event of undetermined intent
0.535 0.465 0.000
Y00-Y09 Assault
0.535 0.465 0.000
X85-X99 Assault
0.535 0.465 0.000
X60-X84 Intentional self-harm
0.535 0.465 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.535 0.465 0.000
X50-X57 Overexertion, travel and privation
0.535 0.465 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.535 0.465 0.000
X30-X39 Exposure to forces of nature
0.535 0.465 0.000
X20-X29 Contact with venomous animals and plants
0.535 0.465 0.000
X10-X19 Contact with heat and hot substances
0.535 0.465 0.000
X00-X09 Exposure to smoke, fire and flames
0.535 0.465 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.535 0.465 0.000
W75-W84 Other accidental threats to breathing
0.535 0.465 0.000
W65-W74 Accidental drowning and submersion
0.535 0.465 0.000
W50-W64 Exposure to animate mechanical forces
0.535 0.465 0.000
W20-W49 Exposure to inanimate mechanical forces
0.535 0.465 0.000
V98-V99 Other and unspecified transport accidents
0.535 0.465 0.000
V95-V97 Air and space transport accidents
0.535 0.465 0.000
V90-V94 Water transport accidents
0.535 0.465 0.000
V80-V89 Other land transport accidents
0.535 0.465 0.000
V70-V79 Bus occupant injured in transport accident
0.535 0.465 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.535 0.465 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.535 0.465 0.000
V40-V49 Car occupant injured in transport accident
0.535 0.465 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.535 0.465 0.000
V01-V09 Pedestrian injured in transport accident
0.535 0.465 0.000
M11 Other crystal arthropathies
0.535 0.465 0.000
W18 Other fall on same level
0.535 0.465 0.000
R40 Somnolence, stupor and coma
0.535 0.465 0.000
M84 Disorders of continuity of bone
0.534 0.466 0.000
M83 Adult osteomalacia
0.534 0.466 0.000
M82 Osteoporosis in diseases classified elsewhere
0.534 0.466 0.000
M93 Other osteochondropathies
0.534 0.466 0.000
M92 Other juvenile osteochondrosis
0.534 0.466 0.000
M91 Juvenile osteochondrosis of hip and pelvis
0.534 0.466 0.000
E06.3 Autoimmune thyroiditis
0.533 0.466 0.000
M24 Other specific joint derangements
0.533 0.467 0.000
K14 Diseases of tongue
0.533 0.467 0.000
K81 Cholecystitis
0.532 0.468 0.000
H65-H75 Diseases of middle ear and mastoid
0.531 0.469 0.000
R42 Dizziness and giddiness
0.530 0.470 0.000
M70.6 Trochanteric bursitis
0.529 0.471 0.000
K51.5 Mucosal proctocolitis
0.528 0.472 0.000
K51.4 Pseudopolyposis of colon
0.528 0.472 0.000
K51.1 Ulcerative (chronic) ileocolitis
0.528 0.472 0.000
K51.0 Ulcerative (chronic) enterocolitis
0.528 0.472 0.000
M19.01 Primary arthrosis of other joints (Shoulder region)
0.527 0.473 0.000
M54.19 Radiculopathy (Site unspecified)
0.527 0.473 0.000
M54.18 Radiculopathy (Sacral and sacrococcygeal region)
0.527 0.473 0.000
M54.17 Radiculopathy (Lumbosacral region)
0.527 0.473 0.000
M54.15 Radiculopathy (Thoracolumbar region)
0.527 0.473 0.000
M54.14 Radiculopathy (Thoracic region)
0.527 0.473 0.000
M54.13 Radiculopathy (Cervicothoracic region)
0.527 0.473 0.000
M54.12 Radiculopathy (Cervical region)
0.527 0.473 0.000
M54.11 Radiculopathy (Occipito-atlanto-axial region)
0.527 0.473 0.000
M54.10 Radiculopathy (Multiple sites in spine)
0.527 0.473 0.000
H60-H62 Diseases of external ear
0.527 0.473 0.000
M43 Other deforming dorsopathies
0.526 0.474 0.000
G90-G99 Other disorders of the nervous system
0.526 0.474 0.000
Q60-Q64 Congenital malformations of the urinary system
0.526 0.474 0.000
M99 Biomechanical lesions, not elsewhere classified
0.525 0.475 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.525 0.475 0.000
K40-K46 Hernia
0.524 0.476 0.000
M81 Osteoporosis without pathological fracture
0.522 0.478 0.000
T78 Adverse effects, not elsewhere classified
0.521 0.478 0.000
K01 Embedded and impacted teeth
0.520 0.480 0.000
D55-D59 Haemolytic anaemias
0.519 0.481 0.000
E55 Vitamin D deficiency
0.519 0.481 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.518 0.482 0.000
K37 Unspecified appendicitis
0.518 0.482 0.000
T92 Sequelae of injuries of upper limb
0.518 0.482 0.000
M42 Spinal osteochondrosis
0.517 0.483 0.000
M41 Scoliosis
0.517 0.483 0.000
M40 Kyphosis and lordosis
0.517 0.483 0.000
S52.1 Fracture of upper end of radius
0.517 0.483 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.517 0.483 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.517 0.483 0.000
M70.9 Unspecified soft tissue disorder related to use, overuse and pressure
0.515 0.484 0.000
M70.8 Other soft tissue disorders related to use, overuse and pressure
0.515 0.484 0.000
M70.7 Other bursitis of hip
0.515 0.484 0.000
M70.5 Other bursitis of knee
0.515 0.484 0.000
M70.4 Prepatellar bursitis
0.515 0.484 0.000
M70.3 Other bursitis of elbow
0.515 0.484 0.000
M70.2 Olecranon bursitis
0.515 0.484 0.000
M70.1 Bursitis of hand
0.515 0.484 0.000
M70.0 Chronic crepitant synovitis of hand and wrist
0.515 0.484 0.000
H90-H95 Other disorders of ear
0.516 0.484 0.000
S52.9 Fracture of forearm, part unspecified
0.514 0.486 0.000
S52.8 Fracture of other parts of forearm
0.514 0.486 0.000
S52.7 Multiple fractures of forearm
0.514 0.486 0.000
S52.4 Fracture of shafts of both ulna and radius
0.514 0.486 0.000
S52.3 Fracture of shaft of radius
0.514 0.486 0.000
S52.2 Fracture of shaft of ulna
0.514 0.486 0.000
K51.2 Ulcerative (chronic) proctitis
0.513 0.487 0.000
Y42.5 Other oestrogens and progestogens
0.513 0.487 0.000
M03 Postinfective and reactive arthropathies in diseases classified elsewhere
0.511 0.489 0.000
M02 Reactive arthropathies
0.511 0.489 0.000
M01 Direct infections of joint in infectious and parasitic diseases classified elsewhere
0.511 0.489 0.000
M00 Pyogenic arthritis
0.511 0.489 0.000
M63 Disorders of muscle in diseases classified elsewhere
0.511 0.489 0.000
M62 Other disorders of muscle
0.511 0.489 0.000
M61 Calcification and ossification of muscle
0.511 0.489 0.000
M60 Myositis
0.511 0.489 0.000
R80 Isolated proteinuria
0.511 0.489 0.000
G30-G32 Other degenerative diseases of the nervous system
0.510 0.490 0.000
K36 Other appendicitis
0.509 0.491 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.509 0.491 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.509 0.491 0.000
E34 Other endocrine disorders
0.509 0.491 0.000
E32 Diseases of thymus
0.509 0.491 0.000
E31 Polyglandular dysfunction
0.509 0.491 0.000
E30 Disorders of puberty, not elsewhere classified
0.509 0.491 0.000
E29 Testicular dysfunction
0.509 0.491 0.000
E28 Ovarian dysfunction
0.509 0.491 0.000
E27 Other disorders of adrenal gland
0.509 0.491 0.000
E26 Hyperaldosteronism
0.509 0.491 0.000
E25 Adrenogenital disorders
0.509 0.491 0.000
E24 Cushing's syndrome
0.509 0.491 0.000
E22 Hyperfunction of pituitary gland
0.509 0.491 0.000
E20 Hypoparathyroidism
0.509 0.491 0.000
M53.9 Dorsopathy, unspecified
0.509 0.491 0.000
M53.8 Other specified dorsopathies
0.509 0.491 0.000
M53.3 Sacrococcygeal disorders, not elsewhere classified
0.509 0.491 0.000
M53.2 Spinal instabilities
0.509 0.491 0.000
M53.1 Cervicobrachial syndrome
0.509 0.491 0.000
M53.0 Cervicocranial syndrome
0.509 0.491 0.000
M18.5 Other secondary arthrosis of first carpometacarpal joint
0.509 0.491 0.000
M18.4 Other secondary arthrosis of first carpometacarpal joints, bilateral
0.509 0.491 0.000
M18.3 Other posttraumatic arthrosis of first carpometacarpal joint
0.509 0.491 0.000
M18.2 Posttraumatic arthrosis of first carpometacarpal joints, bilateral
0.509 0.491 0.000
M18.0 Primary arthrosis of first carpometacarpal joints, bilateral
0.509 0.491 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.508 0.492 0.000
R27 Other lack of coordination
0.508 0.492 0.000
Chapter I Certain infectious and parasitic diseases
0.508 0.492 0.000
M48.0 Spinal stenosis
0.508 0.492 0.000
M54.09 Panniculitis affecting regions of neck and back (Site unspecified)
0.507 0.493 0.000
M54.08 Panniculitis affecting regions of neck and back (Sacral and sacrococcygeal region)
0.507 0.493 0.000
M54.07 Panniculitis affecting regions of neck and back (Lumbosacral region)
0.507 0.493 0.000
M54.06 Panniculitis affecting regions of neck and back (Lumbar region)
0.507 0.493 0.000
M54.05 Panniculitis affecting regions of neck and back (Thoracolumbar region)
0.507 0.493 0.000
M54.04 Panniculitis affecting regions of neck and back (Thoracic region)
0.507 0.493 0.000
M54.03 Panniculitis affecting regions of neck and back (Cervicothoracic region)
0.507 0.493 0.000
M54.02 Panniculitis affecting regions of neck and back (Cervical region)
0.507 0.493 0.000
M54.01 Panniculitis affecting regions of neck and back (Occipito-atlanto-axial region)
0.507 0.493 0.000
M54.00 Panniculitis affecting regions of neck and back (Multiple sites in spine)
0.507 0.493 0.000
M54.39 Sciatica (Site unspecified)
0.507 0.493 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.507 0.493 0.000
M54.37 Sciatica (Lumbosacral region)
0.507 0.493 0.000
M54.36 Sciatica (Lumbar region)
0.507 0.493 0.000
M54.35 Sciatica (Thoracolumbar region)
0.507 0.493 0.000
M54.34 Sciatica-Thoracic
0.507 0.493 0.000
M54.33 Sciatica-Cervicothoracic
0.507 0.493 0.000
M54.32 Sciatica-Cervical
0.507 0.493 0.000
M54.31 Sciatica-Occipit-atl-axl
0.507 0.493 0.000
M54.30 Sciatica (Multiple sites in spine)
0.507 0.493 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.507 0.493 0.000
M54.48 Lumbago with sciatica (Sacral and sacrococcygeal region)
0.507 0.493 0.000
M54.47 Lumbago with sciatica (Lumbosacral region)
0.507 0.493 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.507 0.493 0.000
M54.45 Lumbago with sciatica (Thoracolumbar region)
0.507 0.493 0.000
M54.44 Lumbago with sciatica-Thoracic
0.507 0.493 0.000
M54.43 Lumbago with sciatica-Cervicothoracic
0.507 0.493 0.000
M54.42 Lumbago with sciatica-Cervical
0.507 0.493 0.000
M54.41 Lumbago with sciatica-Occipit-atl-axl
0.507 0.493 0.000
M54.40 Lumbago with sciatica (Multiple sites in spine)
0.507 0.493 0.000
M54.69 Pain in thoracic spine-Site unspe
0.507 0.493 0.000
M54.68 Pain in thoracic spine-Sacral/sacrococ
0.507 0.493 0.000
M54.67 Pain in thoracic spine-Lumbosacral
0.507 0.493 0.000
M54.66 Pain in thoracic spine-Lumbar
0.507 0.493 0.000
M54.65 Pain in thoracic spine (Thoracolumbar region)
0.507 0.493 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.507 0.493 0.000
M54.63 Pain in thoracic spine (Cervicothoracic region)
0.507 0.493 0.000
M54.62 Pain in thoracic spine-Cervical
0.507 0.493 0.000
M54.61 Pain in thoracic spine-Occipit-atl-axl
0.507 0.493 0.000
M54.60 Pain in thoracic spine (Multiple sites in spine)
0.507 0.493 0.000
M54.89 Other dorsalgia (Site unspecified)
0.507 0.493 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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