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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs118182320
log Bayes Factor = 24.3873
Chromosome 8   position 80,951,882  (GRCh37) Explore rs118182320 on Ensembl!
Variant rs118182320 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
J40-J47 Chronic lower respiratory diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
R50-R69 General symptoms and signs
0.999 0.001 0.000
I20 Angina pectoris
0.998 0.002 0.000
I25 Chronic ischaemic heart disease
0.998 0.002 0.000
J45 Asthma
0.998 0.002 0.000
J45.9 Asthma, unspecified
0.997 0.003 0.000
R51 Headache
0.996 0.004 0.000
J44 Other chronic obstructive pulmonary disease
0.995 0.005 0.000
I10-I15 Hypertensive diseases
0.994 0.006 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.994 0.006 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.991 0.009 0.000
Z95.1 Presence of aortocoronary bypass graft
0.991 0.009 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.990 0.010 0.000
I10 Essential (primary) hypertension
0.988 0.012 0.000
E70-E90 Metabolic disorders
0.987 0.013 0.000
I20.9 Angina pectoris, unspecified
0.985 0.015 0.000
Z86 Personal history of certain other diseases
0.977 0.023 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.976 0.024 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.970 0.030 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.969 0.031 0.000
Chapter XX External causes of morbidity and mortality
0.965 0.035 0.000
K40-K46 Hernia
0.962 0.038 0.000
Z86.4 Personal history of psychoactive substance abuse
0.962 0.038 0.000
K70-K77 Diseases of liver
0.959 0.041 0.000
Chapter II Neoplasms
0.956 0.044 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.951 0.049 0.000
I20.0 Unstable angina
0.947 0.053 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.944 0.056 0.000
R53 Malaise and fatigue
0.943 0.057 0.000
Z92 Personal history of medical treatment
0.942 0.058 0.000
Z60 Problems related to social environment
0.941 0.059 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.940 0.060 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.936 0.064 0.000
L20-L30 Dermatitis and eczema
0.935 0.065 0.000
Chapter I Certain infectious and parasitic diseases
0.935 0.065 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.932 0.068 0.000
Z87 Personal history of other diseases and conditions
0.924 0.076 0.000
J09-J18 Influenza and pneumonia
0.922 0.078 0.000
Z60.2 Living alone
0.921 0.079 0.000
K35-K38 Diseases of appendix
0.920 0.080 0.000
Z93 Artificial opening status
0.918 0.082 0.000
K43 Ventral hernia
0.915 0.085 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.914 0.086 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.913 0.087 0.000
E83 Disorders of mineral metabolism
0.911 0.089 0.000
Chapter VI Diseases of the nervous system
0.910 0.090 0.000
K76 Other diseases of liver
0.906 0.094 0.000
E20-E35 Disorders of other endocrine glands
0.902 0.098 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.901 0.099 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.901 0.099 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.893 0.107 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.891 0.109 0.000
Z99.3 Dependence on wheelchair
0.890 0.109 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.888 0.112 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.888 0.112 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.883 0.117 0.000
L30 Other dermatitis
0.882 0.118 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.878 0.122 0.000
E10-E14 Diabetes mellitus
0.878 0.122 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.878 0.122 0.000
Z86.0 Personal history of other neoplasms
0.876 0.124 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.875 0.125 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.871 0.129 0.000
L60-L75 Disorders of skin appendages
0.870 0.130 0.000
Z99.2 Dependence on renal dialysis
0.870 0.130 0.000
K35 Acute appendicitis
0.869 0.131 0.000
J18 Pneumonia, organism unspecified
0.865 0.135 0.000
K46 Unspecified abdominal hernia
0.864 0.136 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.863 0.137 0.000
D60-D64 Aplastic and other anaemias
0.862 0.138 0.000
K43.9 Ventral hernia without obstruction or gangrene
0.856 0.144 0.000
Z92.3 Personal history of irradiation
0.855 0.145 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.855 0.145 0.000
Chapter VIII Diseases of the ear and mastoid process
0.852 0.148 0.000
I21 Acute myocardial infarction
0.852 0.148 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.848 0.152 0.000
L30.9 Dermatitis, unspecified
0.844 0.156 0.000
I25.2 Old myocardial infarction
0.843 0.157 0.000
S20-S29 Injuries to the thorax
0.842 0.158 0.000
Y86 Sequelae of other accidents
0.842 0.158 0.000
K42 Umbilical hernia
0.840 0.160 0.000
B95-B98 Bacterial, viral and other infectious agents
0.834 0.166 0.000
C34 Malignant neoplasm of bronchus and lung
0.831 0.169 0.000
Z87.4 Personal history of diseases of the genito-urinary system
0.831 0.169 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.830 0.170 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.829 0.171 0.000
E83.5 Disorders of calcium metabolism
0.823 0.177 0.000
K76.6 Portal hypertension
0.823 0.177 0.000
E14 Unspecified diabetes mellitus
0.822 0.178 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.822 0.178 0.000
I20.8 Other forms of angina pectoris
0.821 0.179 0.000
J47 Bronchiectasis
0.820 0.180 0.000
R54 Senility
0.820 0.180 0.000
K12 Stomatitis and related lesions
0.820 0.180 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.817 0.183 0.000
E89.0 Postprocedural hypothyroidism
0.817 0.183 0.000
R40 Somnolence, stupor and coma
0.817 0.183 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.814 0.186 0.000
J30-J39 Other diseases of upper respiratory tract
0.814 0.186 0.000
I12 Hypertensive renal disease
0.813 0.187 0.000
A00-A09 Intestinal infectious diseases
0.810 0.190 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.810 0.190 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.810 0.190 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.809 0.191 0.000
S40-S49 Injuries to the shoulder and upper arm
0.808 0.192 0.000
R52 Pain, not elsewhere classified
0.805 0.195 0.000
R25 Abnormal involuntary movements
0.805 0.195 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.802 0.198 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.802 0.198 0.000
K01 Embedded and impacted teeth
0.800 0.200 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.800 0.200 0.000
Chapter VII Diseases of the eye and adnexa
0.798 0.202 0.000
L03 Cellulitis
0.797 0.203 0.000
Z85 Personal history of malignant neoplasm
0.796 0.204 0.000
K46.9 Unspecified abdominal hernia without obstruction or gangrene
0.794 0.206 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.794 0.206 0.000
L27 Dermatitis due to substances taken internally
0.793 0.207 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
G40-G47 Episodic and paroxysmal disorders
0.789 0.211 0.000
C34.1 Upper lobe, bronchus or lung
0.788 0.212 0.000
I05-I09 Chronic rheumatic heart diseases
0.787 0.213 0.000
E50-E64 Other nutritional deficiencies
0.786 0.213 0.000
K76.8 Other specified diseases of liver
0.784 0.216 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.783 0.216 0.000
Z93.3 Colostomy status
0.783 0.217 0.000
E00-E07 Disorders of thyroid gland
0.783 0.217 0.000
Z87.0 Personal history of diseases of the respiratory system
0.783 0.217 0.000
J60-J70 Lung diseases due to external agents
0.782 0.218 0.000
C90.0 Multiple myeloma
0.779 0.221 0.000
J18.1 Lobar pneumonia, unspecified
0.776 0.224 0.000
D61 Other aplastic anaemias
0.776 0.224 0.000
R55 Syncope and collapse
0.775 0.225 0.000
D50-D53 Nutritional anaemias
0.774 0.226 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.773 0.227 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.772 0.228 0.000
R61 Hyperhidrosis
0.772 0.228 0.000
I20.1 Angina pectoris with documented spasm
0.771 0.229 0.000
H53-H54 Visual disturbances and blindness
0.771 0.229 0.000
C91 Lymphoid leukaemia
0.770 0.230 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.769 0.231 0.000
K43.0 Ventral hernia with obstruction, without gangrene
0.769 0.231 0.000
K75 Other inflammatory liver diseases
0.769 0.231 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.767 0.233 0.000
S60-S69 Injuries to the wrist and hand
0.766 0.234 0.000
R50 Fever of unknown origin
0.766 0.234 0.000
Z83 Family history of other specific disorders
0.765 0.235 0.000
S70-S79 Injuries to the hip and thigh
0.765 0.235 0.000
T66-T78 Other and unspecified effects of external causes
0.763 0.237 0.000
K74 Fibrosis and cirrhosis of liver
0.763 0.237 0.000
Z99.8 Dependence on other enabling machines and devices
0.763 0.237 0.000
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue
0.762 0.238 0.000
E22 Hyperfunction of pituitary gland
0.762 0.238 0.000
W00-W19 Falls
0.761 0.239 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.757 0.243 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.757 0.243 0.000
K35.0 Acute appendicitis with generalised peritonitis
0.757 0.243 0.000
E88 Other metabolic disorders
0.754 0.246 0.000
K35.8 Acute appendicitis, other and unspecified
0.753 0.247 0.000
Z93.2 Ileostomy status
0.752 0.248 0.000
Z63 Other problems related to primary support group, including family circumstances
0.752 0.248 0.000
H60-H62 Diseases of external ear
0.751 0.248 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.751 0.249 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.750 0.250 0.000
L72.0 Epidermal cyst
0.749 0.251 0.000
W20-W49 Exposure to inanimate mechanical forces
0.747 0.253 0.000
Z29 Need for other prophylactic measures
0.747 0.253 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.747 0.253 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.746 0.254 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.746 0.254 0.000
J18.9 Pneumonia, unspecified
0.744 0.256 0.000
E14.3 With ophthalmic complications
0.744 0.256 0.000
R25.1 Tremor, unspecified
0.744 0.256 0.000
D10-D36 Benign neoplasms
0.742 0.258 0.000
G90-G99 Other disorders of the nervous system
0.741 0.259 0.000
R60 Oedema, not elsewhere classified
0.741 0.259 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.740 0.260 0.000
Y85 Sequelae of transport accidents
0.738 0.262 0.000
X60-X84 Intentional self-harm
0.737 0.263 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.737 0.263 0.000
G20-G26 Extrapyramidal and movement disorders
0.736 0.264 0.000
E86 Volume depletion
0.735 0.265 0.000
H53 Visual disturbances
0.735 0.265 0.000
S00-S09 Injuries to the head
0.734 0.266 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.733 0.267 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.731 0.269 0.000
K35.3 Acute appendicitis with localized peritonitis
0.731 0.269 0.000
A30-A49 Other bacterial diseases
0.730 0.269 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.726 0.274 0.000
E83.4 Disorders of magnesium metabolism
0.723 0.277 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.723 0.277 0.000
S50-S59 Injuries to the elbow and forearm
0.723 0.277 0.000
S90-S99 Injuries to the ankle and foot
0.722 0.278 0.000
K04 Diseases of pulp and periapical tissues
0.722 0.278 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
R42 Dizziness and giddiness
0.717 0.283 0.000
Z89 Acquired absence of limb
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
Z81 Family history of mental and behavioural disorders
0.717 0.283 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.717 0.283 0.000
J41 Simple and mucopurulent chronic bronchitis
0.717 0.283 0.000
K42.9 Umbilical hernia without obstruction or gangrene
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.716 0.283 0.000
K72 Hepatic failure, not elsewhere classified
0.716 0.283 0.000
E40-E46 Malnutrition
0.716 0.284 0.000
R68 Other general symptoms and signs
0.716 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.716 0.284 0.000
R62 Lack of expected normal physiological development
0.716 0.284 0.000
R57 Shock, not elsewhere classified
0.716 0.284 0.000
R64 Cachexia
0.716 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.716 0.284 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
J46 Status asthmaticus
0.716 0.284 0.000
J45.8 Mixed asthma
0.715 0.284 0.000
J45.1 Nonallergic asthma
0.715 0.284 0.000
E87.0 Hyperosmolality and hypernatraemia
0.715 0.285 0.000
J42 Unspecified chronic bronchitis
0.715 0.285 0.000
D61.9 Aplastic anaemia, unspecified
0.714 0.286 0.000
I15 Secondary hypertension
0.713 0.287 0.000
I13 Hypertensive heart and renal disease
0.713 0.287 0.000
I11 Hypertensive heart disease
0.713 0.287 0.000
T51 Toxic effect of alcohol
0.713 0.287 0.000
Z95.3 Presence of xenogenic heart valve
0.712 0.288 0.000
C73 Malignant neoplasm of thyroid gland
0.712 0.288 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.712 0.288 0.000
Y88 Sequelae of surgical and medical care as external cause
0.712 0.288 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.712 0.288 0.000
K02 Dental caries
0.712 0.288 0.000
O80-O84 Delivery
0.712 0.288 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
K76.9 Liver disease, unspecified
0.711 0.289 0.000
T79-T79 Certain early complications of trauma
0.710 0.290 0.000
T33-T35 Frostbite
0.710 0.290 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.710 0.290 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.710 0.290 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.710 0.290 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.710 0.290 0.000
T00-T07 Injuries involving multiple body regions
0.710 0.290 0.000
S10-S19 Injuries to the neck
0.710 0.290 0.000
R59 Enlarged lymph nodes
0.710 0.290 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.709 0.291 0.000
J30 Vasomotor and allergic rhinitis
0.709 0.291 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.708 0.292 0.000
E85 Amyloidosis
0.708 0.292 0.000
E84 Cystic fibrosis
0.708 0.292 0.000
E79 Disorders of purine and pyrimidine metabolism
0.708 0.292 0.000
E77 Disorders of glycoprotein metabolism
0.708 0.292 0.000
E76 Disorders of glycosaminoglycan metabolism
0.708 0.292 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.708 0.292 0.000
E74 Other disorders of carbohydrate metabolism
0.708 0.292 0.000
E73 Lactose intolerance
0.708 0.292 0.000
E72 Other disorders of amino-acid metabolism
0.708 0.292 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.708 0.292 0.000
E70 Disorders of aromatic amino-acid metabolism
0.708 0.292 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.708 0.292 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.708 0.292 0.000
Z93.5 Cystostomy status
0.707 0.293 0.000
I22 Subsequent myocardial infarction
0.707 0.293 0.000
A09.9 Gastroenteritis and colitis of unspecified origin
0.707 0.293 0.000
R52.9 Pain, unspecified
0.707 0.293 0.000
L08 Other local infections of skin and subcutaneous tissue
0.706 0.294 0.000
K01.1 Impacted teeth
0.705 0.295 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.704 0.296 0.000
Z95.4 Presence of other heart-valve replacement
0.703 0.296 0.000
E14.9 Without complications
0.703 0.297 0.000
E27 Other disorders of adrenal gland
0.702 0.298 0.000
K12.1 Other forms of stomatitis
0.701 0.299 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.701 0.299 0.000
L03.9 Cellulitis, unspecified
0.700 0.299 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.700 0.300 0.000
D00-D09 In situ neoplasms
0.700 0.300 0.000
L10-L14 Bullous disorders
0.699 0.300 0.000
I21.9 Acute myocardial infarction, unspecified
0.699 0.301 0.000
E23 Hypofunction and other disorders of pituitary gland
0.699 0.301 0.000
D62 Acute posthaemorrhagic anaemia
0.699 0.301 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.699 0.301 0.000
Z72 Problems related to lifestyle
0.698 0.302 0.000
Z87.2 Personal history of diseases of the skin and subcutaneous tissue
0.698 0.302 0.000
I21.4 Acute subendocardial myocardial infarction
0.697 0.303 0.000
R47-R49 Symptoms and signs involving speech and voice
0.696 0.304 0.000
I85 Oesophageal varices
0.696 0.304 0.000
E87.5 Hyperkalaemia
0.695 0.304 0.000
Z99.9 Dependence on unspecified enabling machine and device
0.695 0.305 0.000
Z99.4 Dependence on artificial heart
0.695 0.305 0.000
Z99.1 Dependence on respirator
0.695 0.305 0.000
Z99.0 Dependence on aspirator
0.695 0.305 0.000
Z85.4 Personal history of malignant neoplasm of genital organs
0.695 0.305 0.000
Z65 Problems related to other psychosocial circumstances
0.695 0.305 0.000
Z64 Problems related to certain psychosocial circumstances
0.695 0.305 0.000
Z62 Other problems related to upbringing
0.695 0.305 0.000
Z61 Problems related to negative life events in childhood
0.695 0.305 0.000
Z59 Problems related to housing and economic circumstances
0.695 0.305 0.000
Z58 Problems related to physical environment
0.695 0.305 0.000
Z56 Problems related to employment and unemployment
0.695 0.305 0.000
Z55 Problems related to education and literacy
0.695 0.305 0.000
Z57 Occupational exposure to risk-factors
0.694 0.306 0.000
K07 Dentofacial anomalies [including malocclusion]
0.694 0.306 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.694 0.306 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.694 0.306 0.000
D51 Vitamin B12 deficiency anaemia
0.693 0.307 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.693 0.307 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
Y35-Y36 Legal intervention and operations of war
0.692 0.308 0.000
Y10-Y34 Event of undetermined intent
0.692 0.308 0.000
Y00-Y09 Assault
0.692 0.308 0.000
X85-X99 Assault
0.692 0.308 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.692 0.308 0.000
X50-X57 Overexertion, travel and privation
0.692 0.308 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.692 0.308 0.000
X30-X39 Exposure to forces of nature
0.692 0.308 0.000
X20-X29 Contact with venomous animals and plants
0.692 0.308 0.000
X10-X19 Contact with heat and hot substances
0.692 0.308 0.000
X00-X09 Exposure to smoke, fire and flames
0.692 0.308 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.692 0.308 0.000
W75-W84 Other accidental threats to breathing
0.692 0.308 0.000
W65-W74 Accidental drowning and submersion
0.692 0.308 0.000
W50-W64 Exposure to animate mechanical forces
0.692 0.308 0.000
V98-V99 Other and unspecified transport accidents
0.692 0.308 0.000
V95-V97 Air and space transport accidents
0.692 0.308 0.000
V90-V94 Water transport accidents
0.692 0.308 0.000
V80-V89 Other land transport accidents
0.692 0.308 0.000
V70-V79 Bus occupant injured in transport accident
0.692 0.308 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.692 0.308 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.692 0.308 0.000
V40-V49 Car occupant injured in transport accident
0.692 0.308 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.692 0.308 0.000
V01-V09 Pedestrian injured in transport accident
0.692 0.308 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.691 0.309 0.000
Chapter V Mental and behavioural disorders
0.691 0.309 0.000
K45 Other abdominal hernia
0.690 0.310 0.000
K70 Alcoholic liver disease
0.689 0.310 0.000
Z93.0 Tracheostomy status
0.688 0.311 0.000
E83.1 Disorders of iron metabolism
0.688 0.312 0.000
L50-L54 Urticaria and erythema
0.688 0.312 0.000
K77 Liver disorders in diseases classified elsewhere
0.688 0.312 0.000
K73 Chronic hepatitis, not elsewhere classified
0.688 0.312 0.000
K71 Toxic liver disease
0.688 0.312 0.000
I89.0 Lymphoedema, not elsewhere classified
0.687 0.313 0.000
K08 Other disorders of teeth and supporting structures
0.687 0.313 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.686 0.314 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.686 0.314 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.686 0.314 0.000
Z22 Carrier of infectious disease
0.685 0.314 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.685 0.315 0.000
V10-V19 Pedal cyclist injured in transport accident
0.685 0.315 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.685 0.315 0.000
K14 Diseases of tongue
0.684 0.316 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.684 0.316 0.000
Z97 Presence of other devices
0.683 0.317 0.000
S80-S89 Injuries to the knee and lower leg
0.682 0.318 0.000
R40.0 Somnolence
0.681 0.319 0.000
H53.4 Visual field defects
0.681 0.319 0.000
K41 Femoral hernia
0.681 0.319 0.000
R23 Other skin changes
0.681 0.319 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.680 0.320 0.000
I87 Other disorders of veins
0.680 0.320 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.680 0.320 0.000
H65-H75 Diseases of middle ear and mastoid
0.679 0.320 0.000
Y40 Systemic antibiotics
0.679 0.321 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.678 0.322 0.000
E87.6 Hypokalaemia
0.678 0.322 0.000
R46 Symptoms and signs involving appearance and behaviour
0.677 0.323 0.000
R45 Symptoms and signs involving emotional state
0.677 0.323 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.677 0.323 0.000
R43 Disturbances of smell and taste
0.677 0.323 0.000
I12.0 Hypertensive renal disease with renal failure
0.677 0.323 0.000
C91.1 Chronic lymphocytic leukaemia
0.676 0.324 0.000
Z92.9 Personal history of medical treatment, unspecified
0.675 0.325 0.000
Z92.8 Personal history of other medical treatment
0.675 0.325 0.000
Z92.5 Personal history of rehabilitation measures
0.675 0.325 0.000
Z92.0 Personal history of contraception
0.675 0.325 0.000
Z60.9 Problem related to social environment, unspecified
0.675 0.325 0.000
Z60.8 Other problems related to social environment
0.675 0.325 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.675 0.325 0.000
Z60.4 Social exclusion and rejection
0.675 0.325 0.000
Z60.3 Acculturation difficulty
0.675 0.325 0.000
Z60.1 Atypical parenting situation
0.675 0.325 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.675 0.325 0.000
E87.2 Acidosis
0.674 0.326 0.000
Z93.6 Other artificial openings of urinary tract status
0.674 0.326 0.000
K11 Diseases of salivary glands
0.673 0.327 0.000
K42.0 Umbilical hernia with obstruction, without gangrene
0.672 0.328 0.000
J32 Chronic sinusitis
0.671 0.329 0.000
D55-D59 Haemolytic anaemias
0.671 0.329 0.000
L29 Pruritus
0.671 0.329 0.000
L28 Lichen simplex chronicus and prurigo
0.671 0.329 0.000
L25 Unspecified contact dermatitis
0.671 0.329 0.000
L24 Irritant contact dermatitis
0.671 0.329 0.000
L23 Allergic contact dermatitis
0.671 0.329 0.000
L21 Seborrhoeic dermatitis
0.671 0.329 0.000
L20 Atopic dermatitis
0.671 0.329 0.000
L26 Exfoliative dermatitis
0.671 0.329 0.000
L22 Diaper [napkin] dermatitis
0.671 0.329 0.000
B99-B99 Other infectious diseases
0.671 0.329 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.671 0.329 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.671 0.329 0.000
B65-B83 Helminthiases
0.671 0.329 0.000
B50-B64 Protozoal diseases
0.671 0.329 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.671 0.329 0.000
B15-B19 Viral hepatitis
0.671 0.329 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.671 0.329 0.000
A80-A89 Viral infections of the central nervous system
0.671 0.329 0.000
A75-A79 Rickettsioses
0.671 0.329 0.000
A70-A74 Other diseases caused by chlamydiae
0.671 0.329 0.000
A65-A69 Other spirochaetal diseases
0.671 0.329 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.671 0.329 0.000
A20-A28 Certain zoonotic bacterial diseases
0.671 0.329 0.000
A15-A19 Tuberculosis
0.671 0.329 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.670 0.329 0.000
K65-K67 Diseases of peritoneum
0.669 0.331 0.000
K10 Other diseases of jaws
0.669 0.331 0.000
K09 Cysts of oral region, not elsewhere classified
0.669 0.331 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.669 0.331 0.000
K03 Other diseases of hard tissues of teeth
0.669 0.331 0.000
K00 Disorders of tooth development and eruption
0.669 0.331 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.668 0.332 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.668 0.332 0.000
G40 Epilepsy
0.667 0.333 0.000
E10 Insulin-dependent diabetes mellitus
0.667 0.333 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.665 0.335 0.000
C15-C26 Malignant neoplasms of digestive organs
0.665 0.335 0.000
Z85.6 Personal history of leukaemia
0.663 0.337 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.663 0.337 0.000
K12.3 Oral mucositis (ulcerative)
0.662 0.337 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.662 0.337 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.662 0.337 0.000
E22.2 Syndrome of inappropriate secretion of antidiuretic hormone
0.661 0.339 0.000
E16 Other disorders of pancreatic internal secretion
0.661 0.339 0.000
J17 Pneumonia in diseases classified elsewhere
0.661 0.339 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.661 0.339 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.661 0.339 0.000
J12 Viral pneumonia, not elsewhere classified
0.661 0.339 0.000
J11 Influenza, virus not identified
0.661 0.339 0.000
J10 Influenza due to identified influenza virus
0.661 0.339 0.000
J14 Pneumonia due to Haemophilus influenzae
0.661 0.339 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.661 0.339 0.000
J09 Influenza due to certain identified influenza virus
0.661 0.339 0.000
R40.2 Coma, unspecified
0.660 0.340 0.000
R56 Convulsions, not elsewhere classified
0.660 0.340 0.000
K38 Other diseases of appendix
0.660 0.340 0.000
K36 Other appendicitis
0.660 0.340 0.000
Z74 Problems related to care-provider dependency
0.659 0.341 0.000
Z93.9 Artificial opening status, unspecified
0.658 0.342 0.000
Z93.8 Other artificial opening status
0.658 0.342 0.000
Z93.4 Other artificial openings of gastro-intestinal tract status
0.658 0.342 0.000
S42 Fracture of shoulder and upper arm
0.658 0.342 0.000
Z73 Problems related to life-management difficulty
0.658 0.342 0.000
Z93.1 Gastrostomy status
0.657 0.343 0.000
J43 Emphysema
0.657 0.343 0.000
K43.7 Other and unspecified ventral hernia with gangrene
0.656 0.344 0.000
K43.6 Other and unspecified ventral hernia with obstruction, without gangrene
0.656 0.344 0.000
K43.5 Parastomal hernia without obstruction or gangrene
0.656 0.344 0.000
K43.4 Parastomal hernia with gangrene
0.656 0.344 0.000
K43.3 Parastomal hernia with obstruction, without gangrene
0.656 0.344 0.000
K43.2 Incisional hernia without obstruction or gangrene
0.656 0.344 0.000
K43.1 Ventral hernia with gangrene
0.656 0.344 0.000
D80-D89 Certain disorders involving the immune mechanism
0.656 0.344 0.000
H54 Blindness and low vision
0.656 0.344 0.000
C64-C68 Malignant neoplasms of urinary tract
0.656 0.344 0.000
B35-B49 Mycoses
0.655 0.345 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.655 0.345 0.000
O60-O75 Complications of labour and delivery
0.655 0.345 0.000
Y89 Sequelae of other external causes
0.655 0.345 0.000
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent
0.655 0.345 0.000
L73 Other follicular disorders
0.654 0.346 0.000
J95-J99 Other diseases of the respiratory system
0.654 0.346 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.653 0.347 0.000
E83.8 Other disorders of mineral metabolism
0.653 0.347 0.000
E83.3 Disorders of phosphorus metabolism
0.653 0.347 0.000
E83.2 Disorders of zinc metabolism
0.653 0.347 0.000
E83.0 Disorders of copper metabolism
0.653 0.347 0.000
I83 Varicose veins of lower extremities
0.653 0.347 0.000
G70-G73 Diseases of myoneural junction and muscle
0.653 0.347 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.653 0.347 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.653 0.347 0.000
K37 Unspecified appendicitis
0.652 0.348 0.000
H61 Other disorders of external ear
0.651 0.348 0.000
I24 Other acute ischaemic heart diseases
0.651 0.349 0.000
K76.7 Hepatorenal syndrome
0.649 0.351 0.000
K76.5 Hepatic veno-occlusive disease
0.649 0.351 0.000
K76.4 Peliosis hepatis
0.649 0.351 0.000
K76.3 Infarction of liver
0.649 0.351 0.000
K76.2 Central haemorrhagic necrosis of liver
0.649 0.351 0.000
K76.1 Chronic passive congestion of liver
0.649 0.351 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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