TreeWAS – Variant ID: rs11867410

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.999	0.001
# Top node	0.998	0.002
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.995	0.005
Chapter VI Diseases of the nervous system	0.990	0.010
G40-G47 Episodic and paroxysmal disorders	0.990	0.010
S70-S79 Injuries to the hip and thigh	0.989	0.011
M70-M79 Other soft tissue disorders	0.980	0.020
S72 Fracture of femur	0.977	0.023
G43 Migraine	0.974	0.026
M80-M85 Disorders of bone density and structure	0.974	0.026
M75 Shoulder lesions	0.973	0.027
G40 Epilepsy	0.972	0.028
Chapter XX External causes of morbidity and mortality	0.970	0.030
S90-S99 Injuries to the ankle and foot	0.963	0.037
G43.9 Migraine, unspecified	0.963	0.037
S72.0 Fracture of neck of femur	0.960	0.040
Chapter VII Diseases of the eye and adnexa	0.954	0.046
S72.00 Fracture of neck of femur (closed)	0.947	0.053
Chapter XV Pregnancy, childbirth and the puerperium	0.942	0.058
S00-S09 Injuries to the head	0.940	0.060
H53-H54 Visual disturbances and blindness	0.939	0.061
S40-S49 Injuries to the shoulder and upper arm	0.937	0.063
H53 Visual disturbances	0.929	0.071
M75.0 Adhesive capsulitis of shoulder	0.929	0.071
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.926	0.074
M81 Osteoporosis without pathological fracture	0.923	0.077
M75.1 Rotator cuff syndrome	0.918	0.082
M80 Osteoporosis with pathological fracture	0.915	0.085
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.906	0.094
M45-M49 Spondylopathies	0.900	0.100
I84 Haemorrhoids	0.899	0.101
S92 Fracture of foot, except ankle	0.896	0.104
X60-X84 Intentional self-harm	0.896	0.104
I84.8 Unspecified haemorrhoids with other complications	0.888	0.112
H53.8 Other visual disturbances	0.885	0.115
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.885	0.115
I84.3 External thrombosed haemorrhoids	0.885	0.115
S42 Fracture of shoulder and upper arm	0.880	0.120
G45 Transient cerebral ischaemic attacks and related syndromes	0.879	0.121
M81.9 Osteoporosis, unspecified	0.874	0.126
M80.9 Unspecified osteoporosis with pathological fracture	0.873	0.127
H43-H45 Disorders of vitreous body and globe	0.872	0.128
V40-V49 Car occupant injured in transport accident	0.863	0.137
W00-W19 Falls	0.848	0.152
S42.2 Fracture of upper end of humerus	0.848	0.152
O20-O29 Other maternal disorders predominantly related to pregnancy	0.846	0.154
Chapter XXII Codes for special purposes	0.840	0.160
M80.90 Unspecified osteoporosis with pathological fracture (Multiple sites)	0.835	0.165
S09 Other and unspecified injuries of head	0.835	0.165
S10-S19 Injuries to the neck	0.835	0.165
M75.5 Bursitis of shoulder	0.831	0.169
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.829	0.171
S92.0 Fracture of calcaneus	0.829	0.171
M81.99 Osteoporosis, unspecified (Site unspecified)	0.829	0.171
I84.2 Internal haemorrhoids without complication	0.828	0.172
M86-M90 Other osteopathies	0.827	0.173
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.827	0.173
S42.20 Fracture of upper end of humerus (closed)	0.825	0.175
Chapter IV Endocrine, nutritional and metabolic diseases	0.824	0.176
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.822	0.178
S02 Fracture of skull and facial bones	0.816	0.184
S71 Open wound of hip and thigh	0.815	0.185
H53.4 Visual field defects	0.811	0.189
M70 Soft tissue disorders related to use, overuse and pressure	0.809	0.191
G40.5 Special epileptic syndromes	0.807	0.192
M60-M63 Disorders of muscles	0.807	0.193
M46 Other inflammatory spondylopathies	0.798	0.202
S72.2 Subtrochanteric fracture	0.798	0.202
T79-T79 Certain early complications of trauma	0.796	0.204
G44 Other headache syndromes	0.795	0.205
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.792	0.208
S05 Injury of eye and orbit	0.789	0.210
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.788	0.212
S96 Injury of muscle and tendon at ankle and foot level	0.787	0.213
E20-E35 Disorders of other endocrine glands	0.786	0.214
I84.5 External haemorrhoids without complication	0.785	0.215
S72.1 Pertrochanteric fracture	0.784	0.216
S49 Other and unspecified injuries of shoulder and upper arm	0.784	0.216
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified	0.783	0.217
S92.00 Fracture of calcaneus (closed)	0.781	0.219
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.779	0.221
O00-O08 Pregnancy with abortive outcome	0.779	0.221
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.778	0.222
S79 Other and unspecified injuries of hip and thigh	0.777	0.223
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.776	0.223
T58 Toxic effect of carbon monoxide	0.776	0.224
G45.4 Transient global amnesia	0.776	0.224
H25-H28 Disorders of lens	0.774	0.226
T15-T19 Effects of foreign body entering through natural orifice	0.772	0.228
H53.2 Diplopia	0.772	0.228
W50-W64 Exposure to animate mechanical forces	0.771	0.228
G40.8 Other epilepsy	0.771	0.229
H43 Disorders of vitreous body	0.768	0.232
V49 Car occupant injured in other and unspecified transport accidents	0.766	0.234
G40.9 Epilepsy, unspecified	0.762	0.238
I84.6 Residual haemorrhoidal skin tags	0.761	0.239
O80-O84 Delivery	0.760	0.240
Q38-Q45 Other congenital malformations of the digestive system	0.756	0.244
O21 Excessive vomiting in pregnancy	0.756	0.244
H53.0 Amblyopia ex anopsia	0.755	0.245
Chapter IX Diseases of the circulatory system	0.752	0.248
S09.9 Unspecified injury of head	0.752	0.248
Q20-Q28 Congenital malformations of the circulatory system	0.748	0.251
T59 Toxic effect of other gases, fumes and vapours	0.748	0.252
G80-G83 Cerebral palsy and other paralytic syndromes	0.748	0.252
I84.7 Unspecified thrombosed haemorrhoids	0.747	0.253
S01 Open wound of head	0.747	0.253
O85-O92 Complications predominantly related to the puerperium	0.745	0.255
T51 Toxic effect of alcohol	0.745	0.255
S99 Other and unspecified injuries of ankle and foot	0.743	0.257
G20-G26 Extrapyramidal and movement disorders	0.742	0.258
M81.90 Osteoporosis, unspecified (Multiple sites)	0.742	0.258
S72.3 Fracture of shaft of femur	0.741	0.259
S90 Superficial injury of ankle and foot	0.738	0.262
M75.4 Impingement syndrome of shoulder	0.732	0.268
H44 Disorders of globe	0.731	0.269
T63 Toxic effect of contact with venomous animals	0.730	0.270
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level	0.730	0.270
H40-H42 Glaucoma	0.730	0.270
X78 Intentional self-harm by sharp object	0.728	0.272
S80-S89 Injuries to the knee and lower leg	0.728	0.272
M77 Other enthesopathies	0.728	0.272
S39 Other and unspecified injuries of abdomen, lower back and pelvis	0.728	0.272
M46.9 Inflammatory spondylopathy, unspecified	0.726	0.274
M45 Ankylosing spondylitis	0.725	0.275
G43.1 Migraine with aura [classical migraine]	0.723	0.277
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion	0.722	0.278
Y60-Y69 Misadventures to patients during surgical and medical care	0.719	0.281
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.719	0.281
T33-T35 Frostbite	0.716	0.284
T26-T28 Burns and corrosions confined to eye and internal organs	0.716	0.284
T20-T25 Burns and corrosions of external body surface, specified by site	0.716	0.284
T00-T07 Injuries involving multiple body regions	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.715	0.285
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics	0.714	0.285
M75.2 Bicipital tendinitis	0.714	0.286
E21 Hyperparathyroidism and other disorders of parathyroid gland	0.714	0.286
X20-X29 Contact with venomous animals and plants	0.714	0.286
G62 Other polyneuropathies	0.714	0.286
M81.2 Osteoporosis of disuse	0.712	0.288
Y44 Agents primarily affecting blood constituents	0.711	0.289
X58-X59 Accidental exposure to other and unspecified factors	0.710	0.289
O60-O75 Complications of labour and delivery	0.710	0.290
G46 Vascular syndromes of brain in cerebrovascular diseases	0.709	0.290
G41 Status epilepticus	0.709	0.290
S78 Traumatic amputation of hip and thigh	0.709	0.291
S77 Crushing injury of hip and thigh	0.709	0.291
S76 Injury of muscle and tendon at hip and thigh level	0.709	0.291
S75 Injury of blood vessels at hip and thigh level	0.709	0.291
S74 Injury of nerves at hip and thigh level	0.709	0.291
S73 Dislocation, sprain and strain of joint and ligaments of hip	0.709	0.291
V10-V19 Pedal cyclist injured in transport accident	0.708	0.292
X40-X49 Accidental poisoning by and exposure to noxious substances	0.705	0.295
X62.9 Unspecified place	0.703	0.297
M76 Enthesopathies of lower limb, excluding foot	0.702	0.298
M73 Soft tissue disorders in diseases classified elsewhere	0.702	0.298
H10-H13 Disorders of conjunctiva	0.702	0.298
S92.5 Fracture of other toe	0.702	0.298
G50-G59 Nerve, nerve root and plexus disorders	0.702	0.298
M00-M03 Infectious arthropathies	0.702	0.298
S72.9 Fracture of femur, part unspecified	0.701	0.299
S72.8 Fractures of other parts of femur	0.701	0.299
S72.7 Multiple fractures of femur	0.701	0.299
G43.8 Other migraine	0.699	0.301
G43.3 Complicated migraine	0.699	0.301
G43.2 Status migrainosus	0.699	0.301
G43.0 Migraine without aura [common migraine]	0.699	0.301
M83 Adult osteomalacia	0.698	0.302
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.698	0.302
M75.8 Other shoulder lesions	0.697	0.302
M75.9 Shoulder lesion, unspecified	0.697	0.302
G40.7 Petit mal, unspecified, without grand mal seizures	0.697	0.303
G40.4 Other generalised epilepsy and epileptic syndromes	0.697	0.303
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.697	0.303
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.697	0.303
V49.4 Driver injured in collision with other and unspecified motor vehicles in traffic accident	0.697	0.303
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.696	0.304
M50-M54 Other dorsopathies	0.696	0.304
M48 Other spondylopathies	0.696	0.304
Y35-Y36 Legal intervention and operations of war	0.696	0.304
Y10-Y34 Event of undetermined intent	0.696	0.304
Y00-Y09 Assault	0.696	0.304
X85-X99 Assault	0.696	0.304
X30-X39 Exposure to forces of nature	0.696	0.304
X10-X19 Contact with heat and hot substances	0.696	0.304
X00-X09 Exposure to smoke, fire and flames	0.696	0.304
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.696	0.304
W75-W84 Other accidental threats to breathing	0.696	0.304
W65-W74 Accidental drowning and submersion	0.696	0.304
V98-V99 Other and unspecified transport accidents	0.696	0.304
V95-V97 Air and space transport accidents	0.696	0.304
V90-V94 Water transport accidents	0.696	0.304
V70-V79 Bus occupant injured in transport accident	0.696	0.304
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.696	0.304
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.696	0.304
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.696	0.304
V01-V09 Pedestrian injured in transport accident	0.696	0.304
E24 Cushing's syndrome	0.694	0.306
S06 Intracranial injury	0.693	0.307
M40-M43 Deforming dorsopathies	0.692	0.308
I84.1 Internal haemorrhoids with other complications	0.692	0.308
S46 Injury of muscle and tendon at shoulder and upper arm level	0.692	0.308
S42.1 Fracture of scapula	0.692	0.308
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.691	0.308
M84 Disorders of continuity of bone	0.691	0.309
S98 Traumatic amputation of ankle and foot	0.691	0.309
S97 Crushing injury of ankle and foot	0.691	0.309
S95 Injury of blood vessels at ankle and foot level	0.691	0.309
S94 Injury of nerves at ankle and foot level	0.691	0.309
S71.1 Open wound of thigh	0.690	0.310
S80 Superficial injury of lower leg	0.688	0.312
S72.01 Fracture of neck of femur (open)	0.688	0.312
M81.4 Drug-induced osteoporosis	0.688	0.312
M82 Osteoporosis in diseases classified elsewhere	0.687	0.313
I84.0 Internal thrombosed haemorrhoids	0.687	0.313
S91 Open wound of ankle and foot	0.686	0.314
H53.9 Visual disturbance, unspecified	0.683	0.317
X50-X57 Overexertion, travel and privation	0.683	0.317
V80-V89 Other land transport accidents	0.681	0.319
H53.1 Subjective visual disturbances	0.679	0.321
V20-V29 Motorcycle rider injured in transport accident	0.679	0.321
W13 Fall from, out of or through building or structure	0.678	0.322
M80.1 Postoophorectomy osteoporosis with pathological fracture	0.677	0.323
M80.99 Unspecified osteoporosis with pathological fracture (Site unspecified)	0.677	0.323
Y46 Antiepileptics and anti-Parkinsonism drugs	0.677	0.323
G45.9 Transient cerebral ischaemic attack, unspecified	0.676	0.324
W02 Fall involving ice-skates, skis, roller-skates or skateboards	0.674	0.326
S08 Traumatic amputation of part of head	0.674	0.326
S07 Crushing injury of head	0.674	0.326
S04 Injury of cranial nerves	0.674	0.326
S03 Dislocation, sprain and strain of joints and ligaments of head	0.674	0.326
S49.9 Unspecified injury of shoulder and upper arm	0.674	0.326
T36-T50 Poisoning by drugs, medicaments and biological substances	0.673	0.326
M62 Other disorders of muscle	0.672	0.328
S48 Traumatic amputation of shoulder and upper arm	0.672	0.328
S45 Injury of blood vessels at shoulder and upper arm level	0.672	0.328
S44 Injury of nerves at shoulder and upper arm level	0.672	0.328
S47 Crushing injury of shoulder and upper arm	0.672	0.328
H43.1 Vitreous haemorrhage	0.671	0.329
W14 Fall from tree	0.671	0.329
S72.20 Subtrochanteric fracture (closed)	0.670	0.330
M71 Other bursopathies	0.670	0.330
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.669	0.331
V48 Car occupant injured in noncollision transport accident	0.669	0.331
H25 Senile cataract	0.669	0.331
Q00-Q07 Congenital malformations of the nervous system	0.668	0.332
G62.9 Polyneuropathy, unspecified	0.668	0.332
H53.6 Night blindness	0.666	0.334
H53.5 Colour vision deficiencies	0.666	0.334
H53.3 Other disorders of binocular vision	0.666	0.334
W20-W49 Exposure to inanimate mechanical forces	0.666	0.334
Q21 Congenital malformations of cardiac septa	0.664	0.336
T65 Toxic effect of other and unspecified substances	0.664	0.336
T62 Toxic effect of other noxious substances eaten as food	0.664	0.336
T61 Toxic effect of noxious substances eaten as seafood	0.664	0.336
T60 Toxic effect of pesticides	0.664	0.336
T57 Toxic effect of other inorganic substances	0.664	0.336
T56 Toxic effect of metals	0.664	0.336
T54 Toxic effect of corrosive substances	0.664	0.336
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.664	0.336
T52 Toxic effect of organic solvents	0.664	0.336
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.664	0.336
T55 Toxic effect of soaps and detergents	0.664	0.336
G30-G32 Other degenerative diseases of the nervous system	0.663	0.337
W19 Unspecified fall	0.663	0.337
O23 Infections of genito-urinary tract in pregnancy	0.662	0.338
M81.8 Other osteoporosis	0.662	0.338
M81.6 Localised osteoporosis [Lequesne]	0.662	0.338
M81.5 Idiopathic osteoporosis	0.662	0.338
M81.3 Postsurgical malabsorption osteoporosis	0.662	0.338
M81.1 Postoophorectomy osteoporosis	0.662	0.338
M81.0 Postmenopausal osteoporosis	0.662	0.338
Y45 Analgesics, antipyretics and anti-inflammatory drugs	0.662	0.338
S02.9 Fracture of skull and facial bones, part unspecified	0.662	0.338
E22 Hyperfunction of pituitary gland	0.662	0.338
M72 Fibroblastic disorders	0.661	0.339
Y40 Systemic antibiotics	0.661	0.339
S96.1 Injury of muscle and tendon of long extensor muscle of toe at ankle and foot level	0.661	0.339
O82 Single delivery by Caesarean section	0.661	0.339
S10 Superficial injury of neck	0.659	0.340
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.658	0.342
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.658	0.342
S92.2 Fracture of other tarsal bone(s)	0.657	0.343
M80.8 Other osteoporosis with pathological fracture	0.656	0.344
M80.5 Idiopathic osteoporosis with pathological fracture	0.656	0.344
M80.4 Drug-induced osteoporosis with pathological fracture	0.656	0.344
M80.3 Postsurgical malabsorption osteoporosis with pathological fracture	0.656	0.344
M80.2 Osteoporosis of disuse with pathological fracture	0.656	0.344
E21.0 Primary hyperparathyroidism	0.656	0.344
S02.2 Fracture of nasal bones	0.656	0.344
H55-H59 Other disorders of eye and adnexa	0.656	0.344
O68 Labour and delivery complicated by foetal stress [distress]	0.656	0.344
S41 Open wound of shoulder and upper arm	0.655	0.344
M91-M94 Chondropathies	0.655	0.345
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.655	0.345
S01.9 Open wound of head, part unspecified	0.655	0.345
S01.3 Open wound of ear	0.653	0.347
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.653	0.347
M70.5 Other bursitis of knee	0.653	0.347
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.652	0.348
S79.8 Other specified injuries of hip and thigh	0.651	0.349
T79 Certain early complications of trauma, not elsewhere classified	0.651	0.349
I89 Other non-infective disorders of lymphatic vessels and lymph nodes	0.651	0.349
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.651	0.349
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid	0.650	0.350
S05.1 Contusion of eyeball and orbital tissues	0.649	0.351
E50-E64 Other nutritional deficiencies	0.648	0.352
H43.8 Other disorders of vitreous body	0.648	0.352
O28 Abnormal findings on antenatal screening of mother	0.648	0.352
E16 Other disorders of pancreatic internal secretion	0.648	0.352
M89 Other disorders of bone	0.647	0.352
G44.2 Tension-type headache	0.647	0.353
G45.3 Amaurosis fugax	0.647	0.353
H54 Blindness and low vision	0.647	0.353
O26 Maternal care for other conditions predominantly related to pregnancy	0.647	0.353
O04 Medical abortion	0.646	0.354
S92.3 Fracture of metatarsal bone	0.646	0.354
S72.10 Pertrochanteric fracture (closed)	0.646	0.354
M49 Spondylopathies in diseases classified elsewhere	0.645	0.355
G70-G73 Diseases of myoneural junction and muscle	0.644	0.355
T90 Sequelae of injuries of head	0.644	0.356
S92.9 Fracture of foot, unspecified	0.643	0.357
S92.7 Multiple fractures of foot	0.643	0.357
S92.4 Fracture of great toe	0.643	0.357
S92.1 Fracture of talus	0.643	0.357
X84 Intentional self-harm by unspecified means	0.642	0.358
X83 Intentional self-harm by other specified means	0.642	0.358
X82 Intentional self-harm by crashing of motor vehicle	0.642	0.358
X81 Intentional self-harm by jumping or lying before moving object	0.642	0.358
X80 Intentional self-harm by jumping from a high place	0.642	0.358
X79 Intentional self-harm by blunt object	0.642	0.358
X77 Intentional self-harm by steam, hot vapours and hot objects	0.642	0.358
X76 Intentional self-harm by smoke, fire and flames	0.642	0.358
X75 Intentional self-harm by explosive material	0.642	0.358
X74 Intentional self-harm by other and unspecified firearm discharge	0.642	0.358
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge	0.642	0.358
X72 Intentional self-harm by handgun discharge	0.642	0.358
X71 Intentional self-harm by drowning and submersion	0.642	0.358
X70 Intentional self-harm by hanging, strangulation and suffocation	0.642	0.358
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances	0.642	0.358
X68 Intentional self-poisoning by and exposure to pesticides	0.642	0.358
X67 Intentional self-poisoning by and exposure to other gases and vapours	0.642	0.358
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours	0.642	0.358
X65 Intentional self-poisoning by and exposure to alcohol	0.642	0.358
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances	0.642	0.358
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified	0.642	0.358
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system	0.641	0.359
S42.4 Fracture of lower end of humerus	0.641	0.359
S72.4 Fracture of lower end of femur	0.641	0.359
S02.1 Fracture of base of skull	0.641	0.359
T66-T78 Other and unspecified effects of external causes	0.640	0.360
E65-E68 Obesity and other hyperalimentation	0.639	0.361
Chapter VIII Diseases of the ear and mastoid process	0.636	0.364
E28 Ovarian dysfunction	0.636	0.364
S19 Other and unspecified injuries of neck	0.636	0.364
S01.7 Multiple open wounds of head	0.636	0.364
S31 Open wound of abdomen, lower back and pelvis	0.635	0.365
S80.8 Other superficial injuries of lower leg	0.635	0.365
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.634	0.366
Q35-Q37 Cleft lip and cleft palate	0.634	0.366
Q30-Q34 Congenital malformations of the respiratory system	0.634	0.366
M80.0 Postmenopausal osteoporosis with pathological fracture	0.634	0.366
M87 Osteonecrosis	0.634	0.366
O21.2 Late vomiting of pregnancy	0.634	0.366
S42.9 Fracture of shoulder girdle, part unspecified	0.633	0.366
G00-G09 Inflammatory diseases of the central nervous system	0.633	0.367
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.632	0.368
I84.4 External haemorrhoids with other complications	0.632	0.368
O21.0 Mild hyperemesis gravidarum	0.631	0.369
S42.8 Fracture of other parts of shoulder and upper arm	0.631	0.369
S42.7 Multiple fractures of clavicle, scapula and humerus	0.631	0.369
S12 Fracture of neck	0.631	0.369
G45.8 Other transient cerebral ischaemic attacks and related syndromes	0.630	0.370
G45.2 Multiple and bilateral precerebral artery syndromes	0.630	0.370
G45.1 Carotid artery syndrome (hemispheric)	0.630	0.370
G45.0 Vertebro-basilar artery syndrome	0.630	0.370
M70.6 Trochanteric bursitis	0.629	0.371
H25.9 Senile cataract, unspecified	0.628	0.372
Y53 Agents primarily affecting the gastro-intestinal system	0.628	0.372
S40 Superficial injury of shoulder and upper arm	0.627	0.373
M80.98 Unspecified osteoporosis with pathological fracture (Other)	0.627	0.373
S70 Superficial injury of hip and thigh	0.627	0.373
Q50-Q56 Congenital malformations of genital organs	0.627	0.373
M81.97 Osteoporosis, unspecified (Ankle and foot)	0.626	0.374
M81.96 Osteoporosis, unspecified (Lower leg)	0.626	0.374
M81.95 Osteoporosis, unspecified (Pelvic region and thigh)	0.626	0.374
M81.94 Osteoporosis, unspecified (Hand)	0.626	0.374
M81.93 Osteoporosis, unspecified (Forearm)	0.626	0.374
M81.92 Osteoporosis, unspecified (Upper arm)	0.626	0.374
M81.91 Osteoporosis, unspecified (Shoulder region)	0.626	0.374
M80.97 Unspecified osteoporosis with pathological fracture (Ankle and foot)	0.626	0.374
M80.96 Unspecified osteoporosis with pathological fracture (Lower leg)	0.626	0.374
M80.95 Unspecified osteoporosis with pathological fracture (Pelvic region and thigh)	0.626	0.374
M80.94 Unspecified osteoporosis with pathological fracture (Hand)	0.626	0.374
M80.93 Unspecified osteoporosis with pathological fracture (Forearm)	0.626	0.374
M80.92 Unspecified osteoporosis with pathological fracture (Upper arm)	0.626	0.374
M80.91 Unspecified osteoporosis with pathological fracture (Shoulder region)	0.626	0.374
Y44.2 Anticoagulants	0.626	0.374
H45 Disorders of vitreous body and globe in diseases classified elsewhere	0.625	0.375
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.625	0.375
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.625	0.375
O94-O99 Other obstetric conditions, not elsewhere classified	0.624	0.375
S39.9 Unspecified injury of abdomen, lower back and pelvis	0.623	0.377
T59.8 Other specified gases, fumes and vapours	0.621	0.379
O81 Single delivery by forceps and vacuum extractor	0.620	0.380
W06 Fall involving bed	0.620	0.380
S09.8 Other specified injuries of head	0.619	0.381
V47 Car occupant injured in collision with fixed or stationary object	0.619	0.381
V46 Car occupant injured in collision with other nonmotor vehicle	0.619	0.381
V45 Car occupant injured in collision with railway train or railway vehicle	0.619	0.381
V44 Car occupant injured in collision with heavy transport vehicle or bus	0.619	0.381
V43 Car occupant injured in collision with car, pick-up truck or van	0.619	0.381
V42 Car occupant injured in collision with two- or three-wheeled motor vehicle	0.619	0.381
V41 Car occupant injured in collision with pedal cycle	0.619	0.381
V40 Car occupant injured in collision with pedestrian or animal	0.619	0.381
Q43 Other congenital malformations of intestine	0.618	0.382
S05.8 Other injuries of eye and orbit	0.618	0.382
G50 Disorders of trigeminal nerve	0.618	0.382
S14 Injury of nerves and spinal cord at neck level	0.616	0.384
W07 Fall involving chair	0.615	0.385
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.615	0.385
M85 Other disorders of bone density and structure	0.615	0.385
M54 Dorsalgia	0.614	0.386
M46.96 Inflammatory spondylopathy, unspecified (Lumbar region)	0.614	0.386
M86 Osteomyelitis	0.614	0.386
S02.5 Fracture of tooth	0.613	0.387
G54 Nerve root and plexus disorders	0.613	0.387
I80 Phlebitis and thrombophlebitis	0.613	0.387
O03 Spontaneous abortion	0.613	0.387
M05-M14 Inflammatory polyarthropathies	0.611	0.389
S02.4 Fracture of malar and maxillary bones	0.609	0.391
M88 Paget's disease of bone [osteitis deformans]	0.609	0.391
W17 Other fall from one level to another	0.608	0.392
W16 Diving or jumping into water causing injury other than drowning or submersion	0.608	0.392
W15 Fall from cliff	0.608	0.392
W12 Fall on and from scaffolding	0.608	0.392
W11 Fall on and from ladder	0.608	0.392
W09 Fall involving playground equipment	0.608	0.392
W05 Fall involving wheelchair	0.608	0.392
W04 Fall while being carried or supported by other persons	0.608	0.392
W03 Other fall on same level due to collision with, or pushing by, another person	0.608	0.392
W01 Fall on same level from slipping, tripping and stumbling	0.608	0.392
W00 Fall on same level involving ice and snow	0.608	0.392
S42.21 Fracture of upper end of humerus (open)	0.608	0.392
M75.3 Calcific tendinitis of shoulder	0.608	0.392
Y49 Psychotropic drugs, not elsewhere classified	0.608	0.392
X78.0 Home	0.608	0.392
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.606	0.394
O29 Complications of anaesthesia during pregnancy	0.606	0.394
O22 Venous complications in pregnancy	0.606	0.394
O25 Malnutrition in pregnancy	0.606	0.394
S02.3 Fracture of orbital floor	0.606	0.394
T11 Other injuries of upper limb, level unspecified	0.606	0.394
O86 Other puerperal infections	0.606	0.394
Y57 Other and unspecified drugs and medicaments	0.606	0.394
Q39 Congenital malformations of oesophagus	0.604	0.396
Q21.1 Atrial septal defect	0.604	0.396
M90 Osteopathies in diseases classified elsewhere	0.603	0.397
M54.5 Low back pain	0.601	0.399
H25.0 Senile incipient cataract	0.601	0.399
T17 Foreign body in respiratory tract	0.600	0.400
I81 Portal vein thrombosis	0.600	0.400
M46.99 Inflammatory spondylopathy, unspecified (Site unspecified)	0.599	0.401
S09.7 Multiple injuries of head	0.598	0.401
S09.2 Traumatic rupture of ear drum	0.598	0.401
S09.1 Injury of muscle and tendon of head	0.598	0.401
S09.0 Injury of blood vessels of head, not elsewhere classified	0.598	0.401
M45.X9 Ankylosing spondylitis (Site unspecified)	0.599	0.401
S17 Crushing injury of neck	0.598	0.402
S15 Injury of blood vessels at neck level	0.598	0.402
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.598	0.402
S11 Open wound of neck	0.598	0.402
S18 Traumatic amputation at neck level	0.598	0.402
S16 Injury of muscle and tendon at neck level	0.598	0.402
W51 Striking against or bumped into by another person	0.598	0.402
E16.2 Hypoglycaemia, unspecified	0.596	0.404
Y59 Other and unspecified vaccines and biological substances	0.595	0.405
Y58 Bacterial vaccines	0.595	0.405
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.595	0.405
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.595	0.405
Y50 Central nervous system stimulants, not elsewhere classified	0.595	0.405
Y48 Anaesthetics and therapeutic gases	0.595	0.405
Y47 Sedatives, hypnotics and antianxiety drugs	0.595	0.405
S92.01 Fracture of calcaneus (open)	0.594	0.405
H27 Other disorders of lens	0.594	0.406
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis	0.593	0.407
S37 Injury of urinary and pelvic organs	0.593	0.407
S36 Injury of intra-abdominal organs	0.593	0.407
S35 Injury of blood vessels at abdomen, lower back and pelvis level	0.593	0.407
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level	0.593	0.407
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis	0.593	0.407
W55 Bitten or struck by other mammals	0.593	0.407
S42.0 Fracture of clavicle	0.592	0.408
T51.0 Ethanol	0.591	0.409
T63.4 Venom of other arthropods	0.590	0.410
H44.4 Hypotony of eye	0.590	0.410
M47 Spondylosis	0.590	0.410
W10 Fall on and from stairs and steps	0.589	0.411
O00 Ectopic pregnancy	0.588	0.411
E24.9 Cushing's syndrome, unspecified	0.588	0.412

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations