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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12025684
log Bayes Factor = 9.25873
Chromosome 1   position 41,748,642  (GRCh37) Explore rs12025684 on Ensembl!
Variant rs12025684 is part of Cluster X0041

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
1.000 0.000 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.996 0.004 0.000
C44.6 Skin of upper limb, including shoulder
0.994 0.006 0.000
D00-D09 In situ neoplasms
0.991 0.009 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
Chapter V Mental and behavioural disorders
0.985 0.015 0.000
Chapter XX External causes of morbidity and mortality
0.985 0.015 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.980 0.020 0.000
D05 Carcinoma in situ of breast
0.977 0.023 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.977 0.023 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.977 0.023 0.000
C44.3 Skin of other and unspecified parts of face
0.976 0.024 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.972 0.028 0.000
F30-F39 Mood [affective] disorders
0.956 0.044 0.000
T66-T78 Other and unspecified effects of external causes
0.955 0.045 0.000
F31 Bipolar affective disorder
0.949 0.051 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.947 0.053 0.000
C77.1 Intrathoracic lymph nodes
0.938 0.062 0.000
D05.9 Carcinoma in situ of breast, unspecified
0.934 0.066 0.000
D05.1 Intraductal carcinoma in situ
0.932 0.068 0.000
S60-S69 Injuries to the wrist and hand
0.927 0.073 0.000
T78 Adverse effects, not elsewhere classified
0.925 0.075 0.000
S01 Open wound of head
0.923 0.077 0.000
Chapter VII Diseases of the eye and adnexa
0.916 0.084 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.914 0.086 0.000
D04 Carcinoma in situ of skin
0.913 0.087 0.000
T42.4 Benzodiazepines
0.909 0.091 0.000
Q60-Q64 Congenital malformations of the urinary system
0.907 0.093 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.907 0.093 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.903 0.097 0.000
Chapter X Diseases of the respiratory system
0.899 0.101 0.000
S70-S79 Injuries to the hip and thigh
0.895 0.105 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.893 0.107 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.889 0.111 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.888 0.112 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.881 0.119 0.000
S06 Intracranial injury
0.881 0.119 0.000
W20-W49 Exposure to inanimate mechanical forces
0.880 0.120 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.877 0.123 0.000
R30-R39 Symptoms and signs involving the urinary system
0.877 0.123 0.000
S00 Superficial injury of head
0.876 0.124 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.875 0.125 0.000
F60-F69 Disorders of adult personality and behaviour
0.873 0.127 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.872 0.128 0.000
J30-J39 Other diseases of upper respiratory tract
0.872 0.128 0.000
C64-C68 Malignant neoplasms of urinary tract
0.871 0.129 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.871 0.129 0.000
T78.4 Allergy, unspecified
0.870 0.130 0.000
T79-T79 Certain early complications of trauma
0.867 0.133 0.000
F31.9 Bipolar affective disorder, unspecified
0.867 0.133 0.000
J90-J94 Other diseases of pleura
0.866 0.134 0.000
Chapter XXII Codes for special purposes
0.866 0.134 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.864 0.136 0.000
J34 Other disorders of nose and nasal sinuses
0.862 0.138 0.000
S40-S49 Injuries to the shoulder and upper arm
0.862 0.138 0.000
H10-H13 Disorders of conjunctiva
0.859 0.141 0.000
C77.5 Intrapelvic lymph nodes
0.852 0.148 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.850 0.150 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.849 0.151 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.844 0.156 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.843 0.157 0.000
Q61 Cystic kidney disease
0.842 0.158 0.000
S10-S19 Injuries to the neck
0.840 0.159 0.000
S01.8 Open wound of other parts of head
0.840 0.160 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.839 0.161 0.000
C44.2 Skin of ear and external auricular canal
0.837 0.163 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.837 0.163 0.000
R35 Polyuria
0.834 0.166 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.833 0.167 0.000
C79 Secondary malignant neoplasm of other sites
0.831 0.169 0.000
C80 Malignant neoplasm without specification of site
0.829 0.171 0.000
M70-M79 Other soft tissue disorders
0.829 0.171 0.000
F40 Phobic anxiety disorders
0.828 0.172 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.828 0.172 0.000
J34.3 Hypertrophy of nasal turbinates
0.825 0.175 0.000
S00.0 Superficial injury of scalp
0.825 0.175 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.823 0.177 0.000
T42.1 Iminostilbenes
0.822 0.178 0.000
D03 Melanoma in situ
0.822 0.178 0.000
S01.9 Open wound of head, part unspecified
0.815 0.185 0.000
T39.1 4-Aminophenol derivatives
0.813 0.187 0.000
D04.6 Skin of upper limb, including shoulder
0.812 0.188 0.000
R31 Unspecified haematuria
0.809 0.191 0.000
H11 Other disorders of conjunctiva
0.809 0.191 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.808 0.192 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.807 0.192 0.000
M65-M68 Disorders of synovium and tendon
0.807 0.193 0.000
J92 Pleural plaque
0.805 0.195 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.804 0.196 0.000
M45-M49 Spondylopathies
0.804 0.196 0.000
T91 Sequelae of injuries of neck and trunk
0.803 0.197 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.802 0.198 0.000
S05 Injury of eye and orbit
0.802 0.198 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.802 0.198 0.000
S68 Traumatic amputation of wrist and hand
0.800 0.200 0.000
J93 Pneumothorax
0.798 0.202 0.000
R25 Abnormal involuntary movements
0.797 0.203 0.000
V98-V99 Other and unspecified transport accidents
0.796 0.204 0.000
C92 Myeloid leukaemia
0.795 0.205 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.795 0.205 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.794 0.206 0.000
F60 Specific personality disorders
0.793 0.207 0.000
S62 Fracture at wrist and hand level
0.792 0.208 0.000
F40.2 Specific (isolated) phobias
0.790 0.210 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.789 0.210 0.000
V80-V89 Other land transport accidents
0.789 0.211 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.788 0.212 0.000
S06.5 Traumatic subdural haemorrhage
0.784 0.216 0.000
Q65 Congenital deformities of hip
0.783 0.217 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.782 0.218 0.000
C77.4 Inguinal and lower limb lymph nodes
0.780 0.220 0.000
S01.0 Open wound of scalp
0.780 0.220 0.000
H11.0 Pterygium
0.772 0.228 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.772 0.228 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.772 0.228 0.000
J30 Vasomotor and allergic rhinitis
0.769 0.231 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.769 0.231 0.000
W20 Struck by thrown, projected or falling object
0.768 0.232 0.000
X60-X84 Intentional self-harm
0.768 0.232 0.000
F70-F79 Mental retardation
0.767 0.233 0.000
R39 Other symptoms and signs involving the urinary system
0.767 0.233 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.766 0.234 0.000
Q74 Other congenital malformations of limb(s)
0.766 0.234 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.765 0.235 0.000
X10-X19 Contact with heat and hot substances
0.763 0.237 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.763 0.237 0.000
X20-X29 Contact with venomous animals and plants
0.762 0.238 0.000
C91 Lymphoid leukaemia
0.762 0.238 0.000
C67 Malignant neoplasm of bladder
0.761 0.239 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.761 0.239 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.760 0.240 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.759 0.241 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.758 0.242 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.758 0.242 0.000
S79 Other and unspecified injuries of hip and thigh
0.757 0.243 0.000
F34 Persistent mood [affective] disorders
0.756 0.244 0.000
C44.1 Skin of eyelid, including canthus
0.753 0.247 0.000
M67 Other disorders of synovium and tendon
0.752 0.248 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.751 0.249 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.750 0.249 0.000
H53-H54 Visual disturbances and blindness
0.750 0.250 0.000
M77 Other enthesopathies
0.750 0.250 0.000
T78.2 Anaphylactic shock, unspecified
0.749 0.251 0.000
C85.1 B-cell lymphoma, unspecified
0.744 0.256 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.744 0.256 0.000
W50-W64 Exposure to animate mechanical forces
0.744 0.256 0.000
S40 Superficial injury of shoulder and upper arm
0.742 0.258 0.000
J35 Chronic diseases of tonsils and adenoids
0.742 0.258 0.000
S60 Superficial injury of wrist and hand
0.741 0.259 0.000
R32 Unspecified urinary incontinence
0.741 0.259 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.740 0.260 0.000
C44.5 Skin of trunk
0.740 0.260 0.000
S64 Injury of nerves at wrist and hand level
0.739 0.261 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.739 0.261 0.000
M60-M63 Disorders of muscles
0.738 0.262 0.000
C44.0 Skin of lip
0.737 0.263 0.000
W00-W19 Falls
0.736 0.264 0.000
J93.9 Pneumothorax, unspecified
0.735 0.265 0.000
C92.1 Chronic myeloid leukaemia
0.733 0.267 0.000
R25.1 Tremor, unspecified
0.732 0.268 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.732 0.268 0.000
D03.5 Melanoma in situ of trunk
0.731 0.269 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.730 0.270 0.000
J92.9 Pleural plaque without asbestos
0.730 0.270 0.000
C44.4 Skin of scalp and neck
0.728 0.272 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.727 0.273 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.727 0.273 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.727 0.273 0.000
S06.4 Epidural haemorrhage
0.726 0.274 0.000
S70 Superficial injury of hip and thigh
0.724 0.276 0.000
Q80-Q89 Other congenital malformations
0.724 0.276 0.000
Q61.3 Polycystic kidney, unspecified
0.723 0.277 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.722 0.278 0.000
D04.7 Skin of lower limb, including hip
0.722 0.278 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.721 0.279 0.000
F99-F99 Unspecified mental disorder
0.721 0.279 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.720 0.280 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.720 0.280 0.000
R26 Abnormalities of gait and mobility
0.720 0.280 0.000
C81 Hodgkin's disease
0.719 0.281 0.000
F60.9 Personality disorder, unspecified
0.718 0.282 0.000
T91.1 Sequelae of fracture of spine
0.717 0.282 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
S20-S29 Injuries to the thorax
0.716 0.283 0.000
S06.50 Traumatic subdural haemorrhage (without open intracranial wound)
0.715 0.285 0.000
D04.4 Skin of scalp and neck
0.714 0.286 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.714 0.286 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.714 0.286 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.714 0.286 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.714 0.286 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.714 0.286 0.000
T36 Poisoning by systemic antibiotics
0.714 0.286 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.711 0.289 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.711 0.289 0.000
S19 Other and unspecified injuries of neck
0.710 0.290 0.000
D04.3 Skin of other and unspecified parts of face
0.710 0.290 0.000
S01.2 Open wound of nose
0.709 0.291 0.000
S68.1 Traumatic amputation of other single finger (complete)(partial)
0.709 0.291 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
H50 Other strabismus
0.707 0.293 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.706 0.294 0.000
Y35-Y36 Legal intervention and operations of war
0.706 0.294 0.000
Y10-Y34 Event of undetermined intent
0.706 0.294 0.000
Y00-Y09 Assault
0.706 0.294 0.000
X85-X99 Assault
0.706 0.294 0.000
X30-X39 Exposure to forces of nature
0.706 0.294 0.000
X00-X09 Exposure to smoke, fire and flames
0.706 0.294 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.706 0.294 0.000
W75-W84 Other accidental threats to breathing
0.706 0.294 0.000
W65-W74 Accidental drowning and submersion
0.706 0.294 0.000
V95-V97 Air and space transport accidents
0.706 0.294 0.000
V90-V94 Water transport accidents
0.706 0.294 0.000
V70-V79 Bus occupant injured in transport accident
0.706 0.294 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.706 0.294 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.706 0.294 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.706 0.294 0.000
V01-V09 Pedestrian injured in transport accident
0.706 0.294 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.705 0.295 0.000
S65 Injury of blood vessels at wrist and hand level
0.705 0.295 0.000
Q61.2 Polycystic kidney, adult type
0.704 0.296 0.000
F43 Reaction to severe stress, and adjustment disorders
0.704 0.296 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.703 0.297 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.703 0.297 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.703 0.297 0.000
T42.3 Barbiturates
0.703 0.297 0.000
T42.2 Succinimides and oxazolidinediones
0.703 0.297 0.000
T42.0 Hydantoin derivatives
0.703 0.297 0.000
Q66 Congenital deformities of feet
0.702 0.298 0.000
V40-V49 Car occupant injured in transport accident
0.701 0.299 0.000
D05.7 Other carcinoma in situ of breast
0.701 0.299 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.700 0.299 0.000
Q35-Q37 Cleft lip and cleft palate
0.700 0.299 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.700 0.299 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.700 0.300 0.000
T23 Burn and corrosion of wrist and hand
0.700 0.300 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.700 0.300 0.000
Q00-Q07 Congenital malformations of the nervous system
0.698 0.301 0.000
X50-X57 Overexertion, travel and privation
0.698 0.301 0.000
R40 Somnolence, stupor and coma
0.698 0.302 0.000
J30.1 Allergic rhinitis due to pollen
0.697 0.303 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.697 0.303 0.000
C95 Leukaemia of unspecified cell type
0.697 0.303 0.000
C94 Other leukaemias of specified cell type
0.697 0.303 0.000
C93 Monocytic leukaemia
0.697 0.303 0.000
C88 Malignant immunoproliferative diseases
0.697 0.303 0.000
C86 Other specified types of T/NK-cell lymphoma
0.697 0.303 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.697 0.303 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.696 0.303 0.000
T92 Sequelae of injuries of upper limb
0.696 0.304 0.000
Y40 Systemic antibiotics
0.696 0.304 0.000
F20 Schizophrenia
0.696 0.304 0.000
T39.0 Salicylates
0.695 0.305 0.000
Q50-Q56 Congenital malformations of genital organs
0.695 0.305 0.000
Q65.8 Other congenital deformities of hip
0.694 0.306 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.693 0.307 0.000
H43-H45 Disorders of vitreous body and globe
0.692 0.308 0.000
S80-S89 Injuries to the knee and lower leg
0.691 0.309 0.000
W23 Caught, crushed, jammed or pinched in or between objects
0.689 0.311 0.000
S00.7 Multiple superficial injuries of head
0.689 0.311 0.000
S72 Fracture of femur
0.689 0.311 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.689 0.311 0.000
H54 Blindness and low vision
0.688 0.312 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.687 0.313 0.000
S90-S99 Injuries to the ankle and foot
0.685 0.315 0.000
F38 Other mood [affective] disorders
0.685 0.315 0.000
F39 Unspecified mood [affective] disorder
0.685 0.315 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
T75 Effects of other external causes
0.684 0.316 0.000
T74 Maltreatment syndromes
0.684 0.316 0.000
T73 Effects of other deprivation
0.684 0.316 0.000
T70 Effects of air pressure and water pressure
0.684 0.316 0.000
T69 Other effects of reduced temperature
0.684 0.316 0.000
T67 Effects of heat and light
0.684 0.316 0.000
T71 Asphyxiation
0.684 0.316 0.000
T66 Unspecified effects of radiation
0.684 0.316 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.684 0.316 0.000
C44.7 Skin of lower limb, including hip
0.684 0.316 0.000
T20 Burn and corrosion of head and neck
0.684 0.316 0.000
W29 Contact with other powered hand tools and household machinery
0.683 0.317 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.683 0.317 0.000
C43 Malignant melanoma of skin
0.683 0.317 0.000
R27 Other lack of coordination
0.682 0.318 0.000
Y60.0 During surgical operation
0.681 0.319 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.681 0.319 0.000
F30 Manic episode
0.681 0.319 0.000
F31.8 Other bipolar affective disorders
0.681 0.319 0.000
F31.7 Bipolar affective disorder, currently in remission
0.681 0.319 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.681 0.319 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.681 0.319 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.681 0.319 0.000
U80 Agent resistant to penicillin and related antibiotics
0.680 0.320 0.000
W49 Exposure to other and unspecified inanimate mechanical forces
0.680 0.320 0.000
F80-F89 Disorders of psychological development
0.680 0.320 0.000
F42 Obsessive-compulsive disorder
0.680 0.320 0.000
Q61.0 Congenital single renal cyst
0.680 0.320 0.000
M67.8 Other specified disorders of synovium and tendon
0.676 0.324 0.000
S32 Fracture of lumbar spine and pelvis
0.676 0.324 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.675 0.324 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.674 0.326 0.000
Q76 Congenital malformations of spine and bony thorax
0.674 0.326 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.672 0.328 0.000
H49 Paralytic strabismus
0.671 0.329 0.000
J92.0 Pleural plaque with presence of asbestos
0.670 0.330 0.000
T93 Sequelae of injuries of lower limb
0.668 0.332 0.000
S02 Fracture of skull and facial bones
0.667 0.333 0.000
T21 Burn and corrosion of trunk
0.667 0.333 0.000
T51 Toxic effect of alcohol
0.666 0.334 0.000
H10 Conjunctivitis
0.665 0.334 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.665 0.335 0.000
T78.3 Angioneurotic oedema
0.664 0.335 0.000
Q74.2 Other congenital malformations of lower limb(s), including pelvic girdle
0.664 0.336 0.000
S00.3 Superficial injury of nose
0.663 0.336 0.000
T78.9 Adverse effect, unspecified
0.663 0.337 0.000
T78.8 Other adverse effects, not elsewhere classified
0.663 0.337 0.000
R26.2 Difficulty in walking, not elsewhere classified
0.663 0.337 0.000
T68 Hypothermia
0.661 0.339 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
V99 Unspecified transport accident
0.661 0.339 0.000
T31 Burns classified according to extent of body surface involved
0.661 0.339 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.661 0.339 0.000
V10-V19 Pedal cyclist injured in transport accident
0.661 0.339 0.000
T79.3 Post-traumatic wound infection, not elsewhere classified
0.660 0.340 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.659 0.341 0.000
T65 Toxic effect of other and unspecified substances
0.658 0.341 0.000
S79.9 Unspecified injury of hip and thigh
0.658 0.341 0.000
H18 Other disorders of cornea
0.658 0.342 0.000
M47 Spondylosis
0.658 0.342 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.658 0.342 0.000
M80-M85 Disorders of bone density and structure
0.657 0.343 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.655 0.345 0.000
C82.6 Cutaneous follicle centre lymphoma
0.655 0.345 0.000
C82.5 Diffuse follicle centre lymphoma
0.655 0.345 0.000
C82.4 Follicular lymphoma grade IIIb
0.655 0.345 0.000
C82.3 Follicular lymphoma grade IIIa
0.655 0.345 0.000
C82.2 Large cell, follicular
0.655 0.345 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.655 0.345 0.000
C82.0 Small cleaved cell, follicular
0.655 0.345 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.655 0.345 0.000
F23 Acute and transient psychotic disorders
0.655 0.345 0.000
D04.9 Skin, unspecified
0.654 0.346 0.000
D04.8 Skin of other sites
0.654 0.346 0.000
D04.2 Skin of ear and external auricular canal
0.654 0.346 0.000
D04.1 Skin of eyelid, including canthus
0.654 0.346 0.000
D04.0 Skin of lip
0.654 0.346 0.000
D03.6 Melanoma in situ of upper limb, including shoulder
0.654 0.346 0.000
S09 Other and unspecified injuries of head
0.653 0.347 0.000
M45 Ankylosing spondylitis
0.653 0.347 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.653 0.347 0.000
M66 Spontaneous rupture of synovium and tendon
0.651 0.349 0.000
S05.8 Other injuries of eye and orbit
0.651 0.349 0.000
Q64 Other congenital malformations of urinary system
0.651 0.349 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.651 0.349 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.650 0.349 0.000
Q78 Other osteochondrodysplasias
0.650 0.349 0.000
Q77 Osteochondrodysplasia with defects of growth of tubular bones and spine
0.650 0.349 0.000
Q75 Other congenital malformations of skull and face bones
0.650 0.349 0.000
Q73 Reduction defects of unspecified limb
0.650 0.349 0.000
Q72 Reduction defects of lower limb
0.650 0.349 0.000
Q71 Reduction defects of upper limb
0.650 0.349 0.000
Q70 Syndactyly
0.650 0.349 0.000
Q69 Polydactyly
0.650 0.349 0.000
Q68 Other congenital musculoskeletal deformities
0.650 0.349 0.000
Q67 Congenital musculoskeletal deformities of head, face, spine and chest
0.650 0.349 0.000
S10 Superficial injury of neck
0.651 0.349 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.650 0.349 0.000
H11.4 Other conjunctival vascular disorders and cysts
0.650 0.350 0.000
R25.8 Other and unspecified abnormal involuntary movements
0.650 0.350 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.649 0.351 0.000
S62.5 Fracture of thumb
0.649 0.351 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.648 0.351 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.648 0.352 0.000
C67.6 Ureteric orifice
0.648 0.352 0.000
R39.1 Other difficulties with micturition
0.648 0.352 0.000
M77.9 Enthesopathy, unspecified
0.648 0.352 0.000
J91 Pleural effusion in conditions classified elsewhere
0.647 0.352 0.000
S01.1 Open wound of eyelid and periocular area
0.647 0.353 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.647 0.353 0.000
W20.8 Other specified place
0.645 0.355 0.000
R80 Isolated proteinuria
0.644 0.356 0.000
S06.8 Other intracranial injuries
0.643 0.357 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.643 0.357 0.000
S78 Traumatic amputation of hip and thigh
0.642 0.358 0.000
S77 Crushing injury of hip and thigh
0.642 0.358 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.642 0.358 0.000
S75 Injury of blood vessels at hip and thigh level
0.642 0.358 0.000
S74 Injury of nerves at hip and thigh level
0.642 0.358 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.642 0.358 0.000
S71 Open wound of hip and thigh
0.642 0.358 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.641 0.359 0.000
D09 Carcinoma in situ of other and unspecified sites
0.640 0.359 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.640 0.360 0.000
T39.8 Other nonopioid analgesics and antipyretics, not elsewhere classified
0.640 0.360 0.000
T39.4 Antirheumatics, not elsewhere classified
0.640 0.360 0.000
T39.2 Pyrazolone derivatives
0.640 0.360 0.000
S67 Crushing injury of wrist and hand
0.639 0.361 0.000
M62 Other disorders of muscle
0.639 0.361 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.637 0.362 0.000
T95 Sequelae of burns, corrosions and frostbite
0.637 0.363 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.637 0.363 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.637 0.363 0.000
M46 Other inflammatory spondylopathies
0.636 0.364 0.000
S62.6 Fracture of other finger
0.636 0.364 0.000
X41 Accidental poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.635 0.365 0.000
C77.9 Lymph node, unspecified
0.634 0.366 0.000
J35.0 Chronic tonsillitis
0.634 0.366 0.000
M48 Other spondylopathies
0.633 0.367 0.000
C67.2 Lateral wall of bladder
0.633 0.367 0.000
F48 Other neurotic disorders
0.632 0.368 0.000
F44 Dissociative [conversion] disorders
0.632 0.368 0.000
S06.9 Intracranial injury, unspecified
0.632 0.368 0.000
S06.7 Intracranial injury with prolonged coma
0.632 0.368 0.000
S06.1 Traumatic cerebral oedema
0.632 0.368 0.000
S64.4 Injury of digital nerve of other finger
0.631 0.369 0.000
W46 Contact with hypodermic needle
0.631 0.369 0.000
W45 Foreign body or object entering through skin
0.631 0.369 0.000
W43 Exposure to vibration
0.631 0.369 0.000
W42 Exposure to noise
0.631 0.369 0.000
W41 Exposure to high-pressure jet
0.631 0.369 0.000
W40 Explosion of other materials
0.631 0.369 0.000
W39 Discharge of firework
0.631 0.369 0.000
W38 Explosion and rupture of other specified pressurised devices
0.631 0.369 0.000
W37 Explosion and rupture of pressurised tyre, pipe or hose
0.631 0.369 0.000
W36 Explosion and rupture of gas cylinder
0.631 0.369 0.000
W35 Explosion and rupture of boiler
0.631 0.369 0.000
W34 Discharge from other and unspecified firearms
0.631 0.369 0.000
W33 Rifle, shotgun and larger firearm discharge
0.631 0.369 0.000
W32 Handgun discharge
0.631 0.369 0.000
W31 Contact with other and unspecified machinery
0.631 0.369 0.000
W30 Contact with agricultural machinery
0.631 0.369 0.000
W28 Contact with powered lawn mower
0.631 0.369 0.000
W27 Contact with nonpowered hand tool
0.631 0.369 0.000
W26 Contact with knife, sword or dagger
0.631 0.369 0.000
W24 Contact with lifting and transmission devices, not elsewhere classified
0.631 0.369 0.000
W21 Striking against or struck by sports equipment
0.631 0.369 0.000
C02 Malignant neoplasm of other and unspecified parts of tongue
0.630 0.370 0.000
H54.9 Unspecified visual impairment (binocular)
0.630 0.370 0.000
M00-M03 Infectious arthropathies
0.629 0.371 0.000
R36 Urethral discharge
0.629 0.371 0.000
S00.5 Superficial injury of lip and oral cavity
0.628 0.372 0.000
S00.4 Superficial injury of ear
0.628 0.372 0.000
Q63 Other congenital malformations of kidney
0.628 0.372 0.000
W20.0 Home
0.628 0.372 0.000
T50.8 Diagnostic agents
0.627 0.373 0.000
T50.7 Analeptics and opioid receptor antagonists
0.627 0.373 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.627 0.373 0.000
T50.5 Appetite depressants
0.627 0.373 0.000
T50.4 Drugs affecting uric acid metabolism
0.627 0.373 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.627 0.373 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.627 0.373 0.000
T50.1 Loop [high-ceiling] diuretics
0.627 0.373 0.000
T50.0 Mineralocorticoids and their antagonists
0.627 0.373 0.000
J86 Pyothorax
0.627 0.373 0.000
F68 Other disorders of adult personality and behaviour
0.626 0.374 0.000
F66 Psychological and behavioural disorders associated with sexual development and orientation
0.626 0.374 0.000
F65 Disorders of sexual preference
0.626 0.374 0.000
F64 Gender identity disorders
0.626 0.374 0.000
F63 Habit and impulse disorders
0.626 0.374 0.000
F62 Enduring personality changes, not attributable to brain damage and disease
0.626 0.374 0.000
F69 Unspecified disorder of adult personality and behaviour
0.626 0.374 0.000
F61 Mixed and other personality disorders
0.626 0.374 0.000
H50.1 Divergent concomitant strabismus
0.626 0.374 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.625 0.375 0.000
C66 Malignant neoplasm of ureter
0.625 0.375 0.000
C65 Malignant neoplasm of renal pelvis
0.625 0.375 0.000
R40.2 Coma, unspecified
0.624 0.375 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.623 0.377 0.000
T91.2 Sequelae of other fracture of thorax and pelvis
0.623 0.377 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.623 0.377 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.622 0.378 0.000
J93.1 Other spontaneous pneumothorax
0.622 0.378 0.000
M86-M90 Other osteopathies
0.621 0.379 0.000
S01.7 Multiple open wounds of head
0.620 0.380 0.000
F60.3 Emotionally unstable personality disorder
0.620 0.380 0.000
T25 Burn and corrosion of ankle and foot
0.619 0.380 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.619 0.380 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.619 0.380 0.000
Y79 Orthopaedic devices associated with adverse incidents
0.619 0.381 0.000
C77.0 Lymph nodes of head, face and neck
0.618 0.382 0.000
S48 Traumatic amputation of shoulder and upper arm
0.618 0.382 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.618 0.382 0.000
S44 Injury of nerves at shoulder and upper arm level
0.618 0.382 0.000
S41 Open wound of shoulder and upper arm
0.618 0.382 0.000
S47 Crushing injury of shoulder and upper arm
0.618 0.382 0.000
S69 Other and unspecified injuries of wrist and hand
0.618 0.382 0.000
T79.7 Traumatic subcutaneous emphysema
0.618 0.382 0.000
M77.1 Lateral epicondylitis
0.617 0.383 0.000
S19.9 Unspecified injury of neck
0.617 0.383 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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