TreeWAS – Variant ID: rs12154761

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

Hierarchical visualisation How to interpret this figure?

Click here to show this figure without filtering.

Click on a node to zoom (except terminal nodes).

Download this figure in format

Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	1.000	0.000	0.000
Chapter VI Diseases of the nervous system	1.000	0.000	0.000
Chapter II Neoplasms	1.000	0.000	0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.999	0.001	0.000
# Top node	0.999	0.001	0.000
G90-G99 Other disorders of the nervous system	0.999	0.001	0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type	0.996	0.004	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.995	0.005	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.992	0.008	0.000
Chapter XX External causes of morbidity and mortality	0.986	0.014	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.984	0.016	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.983	0.017	0.000
G95 Other diseases of spinal cord	0.981	0.019	0.000
G62 Other polyneuropathies	0.975	0.025	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.975	0.025	0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.974	0.026	0.000
C92 Myeloid leukaemia	0.951	0.049	0.000
G62.9 Polyneuropathy, unspecified	0.948	0.052	0.000
G81 Hemiplegia	0.947	0.053	0.000
C85.1 B-cell lymphoma, unspecified	0.946	0.054	0.000
G95.8 Other specified diseases of spinal cord	0.944	0.056	0.000
S40-S49 Injuries to the shoulder and upper arm	0.941	0.059	0.000
G93 Other disorders of brain	0.940	0.060	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.938	0.062	0.000
C64-C68 Malignant neoplasms of urinary tract	0.937	0.063	0.000
S10-S19 Injuries to the neck	0.926	0.074	0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts	0.917	0.083	0.000
D00-D09 In situ neoplasms	0.917	0.083	0.000
G81.9 Hemiplegia, unspecified	0.910	0.090	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.909	0.091	0.000
C83 Diffuse non-Hodgkin's lymphoma	0.907	0.093	0.000
C67 Malignant neoplasm of bladder	0.905	0.095	0.000
D41.4 Bladder	0.905	0.095	0.000
S50-S59 Injuries to the elbow and forearm	0.904	0.096	0.000
G30-G32 Other degenerative diseases of the nervous system	0.903	0.097	0.000
Chapter VIII Diseases of the ear and mastoid process	0.903	0.097	0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.896	0.104	0.000
C92.0 Acute myeloid leukaemia	0.895	0.105	0.000
G40-G47 Episodic and paroxysmal disorders	0.885	0.115	0.000
G61 Inflammatory polyneuropathy	0.877	0.123	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.876	0.124	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.876	0.124	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.869	0.131	0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.869	0.131	0.000
G82 Paraplegia and tetraplegia	0.868	0.132	0.000
S40 Superficial injury of shoulder and upper arm	0.867	0.133	0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts	0.865	0.135	0.000
G40 Epilepsy	0.865	0.135	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.863	0.137	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.862	0.138	0.000
C67.9 Bladder, unspecified	0.858	0.142	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.853	0.147	0.000
C84 Peripheral and cutaneous T-cell lymphomas	0.849	0.151	0.000
C71 Malignant neoplasm of brain	0.846	0.154	0.000
T82.1 Mechanical complication of cardiac electronic device	0.845	0.155	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.845	0.155	0.000
T66-T78 Other and unspecified effects of external causes	0.844	0.156	0.000
C83.3 Large cell (diffuse)	0.843	0.157	0.000
G95.2 Cord compression, unspecified	0.843	0.157	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.838	0.162	0.000
G62.8 Other specified polyneuropathies	0.837	0.163	0.000
G40.9 Epilepsy, unspecified	0.831	0.169	0.000
Chapter X Diseases of the respiratory system	0.828	0.171	0.001
T86 Failure and rejection of transplanted organs and tissues	0.828	0.172	0.000
G93.0 Cerebral cysts	0.828	0.172	0.000
W50-W64 Exposure to animate mechanical forces	0.823	0.177	0.000
W00-W19 Falls	0.823	0.177	0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified	0.822	0.178	0.000
J30-J39 Other diseases of upper respiratory tract	0.822	0.178	0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants	0.821	0.179	0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.819	0.181	0.000
D46 Myelodysplastic syndromes	0.817	0.183	0.000
G30 Alzheimer's disease	0.816	0.184	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.816	0.184	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.815	0.185	0.000
G95.0 Syringomyelia and syringobulbia	0.814	0.186	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.812	0.188	0.000
J33 Nasal polyp	0.812	0.188	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.803	0.197	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.796	0.204	0.000
G83 Other paralytic syndromes	0.794	0.206	0.000
G61.0 Guillain-Barre syndrome	0.793	0.207	0.000
J32 Chronic sinusitis	0.792	0.208	0.000
S41 Open wound of shoulder and upper arm	0.792	0.208	0.000
G63.2 Diabetic polyneuropathy	0.791	0.209	0.000
W20-W49 Exposure to inanimate mechanical forces	0.791	0.209	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.790	0.210	0.000
S52 Fracture of forearm	0.789	0.211	0.000
D06 Carcinoma in situ of cervix uteri	0.788	0.212	0.000
Y95 Nosocomial condition	0.786	0.214	0.000
C71.9 Brain, unspecified	0.786	0.214	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.785	0.215	0.000
C92.1 Chronic myeloid leukaemia	0.783	0.217	0.000
J33.8 Other polyp of sinus	0.783	0.217	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.781	0.219	0.000
G93.6 Cerebral oedema	0.779	0.221	0.000
D05 Carcinoma in situ of breast	0.779	0.221	0.000
C85.7 Other specified types of non-Hodgkin's lymphoma	0.778	0.222	0.000
J00-J06 Acute upper respiratory infections	0.773	0.227	0.000
H60-H62 Diseases of external ear	0.771	0.229	0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.771	0.229	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.771	0.229	0.000
C90 Multiple myeloma and malignant plasma cell neoplasms	0.765	0.235	0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures	0.764	0.236	0.000
G90 Disorders of autonomic nervous system	0.764	0.236	0.000
T82.4 Mechanical complication of vascular dialysis catheter	0.762	0.238	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.760	0.240	0.000
S19 Other and unspecified injuries of neck	0.758	0.242	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.758	0.242	0.000
G81.1 Spastic hemiplegia	0.757	0.242	0.000
S51 Open wound of forearm	0.757	0.243	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.757	0.243	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.756	0.244	0.000
S11 Open wound of neck	0.756	0.244	0.000
S13 Dislocation, sprain and strain of joints and ligaments at neck level	0.754	0.246	0.000
G30.9 Alzheimer's disease, unspecified	0.754	0.246	0.000
V40-V49 Car occupant injured in transport accident	0.753	0.247	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.753	0.247	0.000
C81 Hodgkin's disease	0.751	0.249	0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified	0.748	0.252	0.000
C32 Malignant neoplasm of larynx	0.746	0.254	0.000
J33.9 Nasal polyp, unspecified	0.745	0.255	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.744	0.256	0.000
S14 Injury of nerves and spinal cord at neck level	0.742	0.258	0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft	0.742	0.258	0.000
C84.4 Peripheral T-cell lymphoma	0.742	0.258	0.000
Y00-Y09 Assault	0.741	0.259	0.000
G93.5 Compression of brain	0.738	0.262	0.000
J35 Chronic diseases of tonsils and adenoids	0.736	0.264	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.735	0.265	0.000
W19 Unspecified fall	0.733	0.267	0.000
G04 Encephalitis, myelitis and encephalomyelitis	0.732	0.268	0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.731	0.269	0.000
H65-H75 Diseases of middle ear and mastoid	0.728	0.272	0.000
L50-L54 Urticaria and erythema	0.728	0.272	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.726	0.274	0.000
G82.2 Paraplegia, unspecified	0.726	0.274	0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified	0.725	0.275	0.000
G93.2 Benign intracranial hypertension	0.725	0.275	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.725	0.275	0.000
C67.6 Ureteric orifice	0.724	0.276	0.000
X50-X57 Overexertion, travel and privation	0.724	0.276	0.000
S90-S99 Injuries to the ankle and foot	0.723	0.277	0.000
G94.2 Hydrocephalus in other diseases classified elsewhere	0.722	0.278	0.000
T98 Sequelae of other and unspecified effects of external causes	0.722	0.278	0.000
G93.3 Postviral fatigue syndrome	0.722	0.278	0.000
C82.2 Large cell, follicular	0.721	0.279	0.000
G93.9 Disorder of brain, unspecified	0.720	0.280	0.000
G97.1 Other reaction to spinal and lumbar puncture	0.719	0.281	0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue	0.717	0.283	0.000
C95 Leukaemia of unspecified cell type	0.717	0.283	0.000
C94 Other leukaemias of specified cell type	0.717	0.283	0.000
C93 Monocytic leukaemia	0.717	0.283	0.000
C88 Malignant immunoproliferative diseases	0.717	0.283	0.000
C86 Other specified types of T/NK-cell lymphoma	0.717	0.283	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.717	0.283	0.000
T91 Sequelae of injuries of neck and trunk	0.717	0.283	0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma	0.716	0.283	0.000
C85.0 Lymphosarcoma	0.716	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.716	0.284	0.000
G92 Toxic encephalopathy	0.716	0.284	0.000
J32.0 Chronic maxillary sinusitis	0.716	0.284	0.000
D44.0 Thyroid gland	0.716	0.284	0.000
Q60-Q64 Congenital malformations of the urinary system	0.714	0.286	0.000
H80-H83 Diseases of inner ear	0.713	0.286	0.000
G64 Other disorders of peripheral nervous system	0.713	0.287	0.000
G91 Hydrocephalus	0.713	0.287	0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.712	0.288	0.000
T33-T35 Frostbite	0.711	0.289	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.711	0.289	0.000
T00-T07 Injuries involving multiple body regions	0.711	0.289	0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma	0.709	0.291	0.000
T68 Hypothermia	0.709	0.291	0.000
L53 Other erythematous conditions	0.708	0.292	0.000
Y35-Y36 Legal intervention and operations of war	0.707	0.293	0.000
Y10-Y34 Event of undetermined intent	0.707	0.293	0.000
X85-X99 Assault	0.707	0.293	0.000
X30-X39 Exposure to forces of nature	0.707	0.293	0.000
X20-X29 Contact with venomous animals and plants	0.707	0.293	0.000
X10-X19 Contact with heat and hot substances	0.707	0.293	0.000
X00-X09 Exposure to smoke, fire and flames	0.707	0.293	0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.707	0.293	0.000
W75-W84 Other accidental threats to breathing	0.707	0.293	0.000
W65-W74 Accidental drowning and submersion	0.707	0.293	0.000
V98-V99 Other and unspecified transport accidents	0.707	0.293	0.000
V95-V97 Air and space transport accidents	0.707	0.293	0.000
V90-V94 Water transport accidents	0.707	0.293	0.000
V70-V79 Bus occupant injured in transport accident	0.707	0.293	0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.707	0.293	0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.707	0.293	0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.707	0.293	0.000
V01-V09 Pedestrian injured in transport accident	0.707	0.293	0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.706	0.294	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.706	0.294	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.704	0.295	0.000
G95.1 Vascular myelopathies	0.703	0.297	0.000
Q50-Q56 Congenital malformations of genital organs	0.703	0.297	0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.703	0.297	0.000
G82.5 Tetraplegia, unspecified	0.700	0.300	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.700	0.300	0.000
G62.2 Polyneuropathy due to other toxic agents	0.699	0.301	0.000
G62.1 Alcoholic polyneuropathy	0.699	0.301	0.000
G62.0 Drug-induced polyneuropathy	0.699	0.301	0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified	0.699	0.301	0.000
D46.9 Myelodysplastic syndrome, unspecified	0.699	0.301	0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis	0.698	0.302	0.000
T82.3 Mechanical complication of other vascular grafts	0.698	0.302	0.000
T82.0 Mechanical complication of heart valve prosthesis	0.698	0.302	0.000
D05.9 Carcinoma in situ of breast, unspecified	0.698	0.302	0.000
T80 Complications following infusion, transfusion and therapeutic injection	0.697	0.303	0.000
T83.5 Infection and inflammatory reaction due to prosthetic device, implant and graft in urinary system	0.696	0.303	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.696	0.304	0.000
D06.9 Cervix, unspecified	0.696	0.304	0.000
G60 Hereditary and idiopathic neuropathy	0.695	0.305	0.000
C66 Malignant neoplasm of ureter	0.695	0.305	0.000
C67.1 Dome of bladder	0.694	0.306	0.000
G97.8 Other postprocedural disorders of nervous system	0.693	0.307	0.000
W44 Foreign body entering into or through eye or natural orifice	0.692	0.308	0.000
T87 Complications peculiar to reattachment and amputation	0.691	0.309	0.000
G93.8 Other specified disorders of brain	0.690	0.310	0.000
L53.9 Erythematous condition, unspecified	0.690	0.310	0.000
Q80-Q89 Other congenital malformations	0.690	0.310	0.000
C67.0 Trigone of bladder	0.689	0.311	0.000
T86.1 Kidney transplant failure and rejection	0.689	0.311	0.000
Y85 Sequelae of transport accidents	0.688	0.311	0.000
H73 Other disorders of tympanic membrane	0.688	0.312	0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.687	0.313	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.687	0.313	0.000
C91 Lymphoid leukaemia	0.686	0.314	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.686	0.314	0.000
S41.1 Open wound of upper arm	0.685	0.315	0.000
J00 Acute nasopharyngitis [common cold]	0.685	0.315	0.000
S42 Fracture of shoulder and upper arm	0.684	0.316	0.000
C92.9 Myeloid leukaemia, unspecified	0.682	0.318	0.000
C92.8 Acute myeloid leukaemia with multilineage dysplasia	0.682	0.318	0.000
C92.7 Other myeloid leukaemia	0.682	0.318	0.000
C92.6 Acute myeloid leukaemia with 11q23-abnormality	0.682	0.318	0.000
C92.5 Acute myelomonocytic leukaemia	0.682	0.318	0.000
C92.4 Acute promyelocytic leukaemia	0.682	0.318	0.000
C92.3 Myeloid sarcoma	0.682	0.318	0.000
C92.2 Subacute myeloid leukaemia	0.682	0.318	0.000
C71.3 Parietal lobe	0.682	0.318	0.000
G81.0 Flaccid hemiplegia	0.679	0.321	0.000
D07.5 Prostate	0.679	0.321	0.000
D41.0 Kidney	0.677	0.323	0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere	0.676	0.324	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.676	0.324	0.000
C32.1 Supraglottis	0.675	0.325	0.000
S48 Traumatic amputation of shoulder and upper arm	0.675	0.325	0.000
S46 Injury of muscle and tendon at shoulder and upper arm level	0.675	0.325	0.000
S45 Injury of blood vessels at shoulder and upper arm level	0.675	0.325	0.000
S44 Injury of nerves at shoulder and upper arm level	0.675	0.325	0.000
S47 Crushing injury of shoulder and upper arm	0.675	0.325	0.000
X60-X84 Intentional self-harm	0.675	0.325	0.000
D39.1 Ovary	0.675	0.325	0.000
C67.4 Posterior wall of bladder	0.674	0.326	0.000
G93.7 Reye's syndrome	0.674	0.326	0.000
S10 Superficial injury of neck	0.674	0.326	0.000
G70-G73 Diseases of myoneural junction and muscle	0.674	0.326	0.000
G40.7 Petit mal, unspecified, without grand mal seizures	0.672	0.327	0.000
H61 Other disorders of external ear	0.672	0.328	0.000
D41.9 Urinary organ, unspecified	0.672	0.328	0.000
D41.7 Other urinary organs	0.672	0.328	0.000
D41.3 Urethra	0.672	0.328	0.000
D41.2 Ureter	0.672	0.328	0.000
D41.1 Renal pelvis	0.672	0.328	0.000
C68 Malignant neoplasm of other and unspecified urinary organs	0.672	0.328	0.000
C65 Malignant neoplasm of renal pelvis	0.672	0.328	0.000
C67.2 Lateral wall of bladder	0.671	0.329	0.000
G80 Infantile cerebral palsy	0.669	0.331	0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.669	0.331	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.667	0.332	0.000
J32.8 Other chronic sinusitis	0.667	0.333	0.000
T86.8 Failure and rejection of other transplanted organs and tissues	0.665	0.335	0.000
V80-V89 Other land transport accidents	0.664	0.336	0.000
S17 Crushing injury of neck	0.664	0.336	0.000
S15 Injury of blood vessels at neck level	0.664	0.336	0.000
S18 Traumatic amputation at neck level	0.664	0.336	0.000
S16 Injury of muscle and tendon at neck level	0.664	0.336	0.000
W55 Bitten or struck by other mammals	0.663	0.337	0.000
D44.3 Pituitary gland	0.663	0.337	0.000
S12 Fracture of neck	0.663	0.337	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.661	0.339	0.000
S52.0 Fracture of upper end of ulna	0.660	0.340	0.000
W19.9 Unspecified place	0.660	0.340	0.000
T79-T79 Certain early complications of trauma	0.659	0.340	0.000
S20-S29 Injuries to the thorax	0.660	0.340	0.000
J90-J94 Other diseases of pleura	0.659	0.341	0.000
G82.1 Spastic paraplegia	0.659	0.341	0.000
H73.8 Other specified disorders of tympanic membrane	0.659	0.341	0.000
G83.4 Cauda equina syndrome	0.659	0.341	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.658	0.342	0.000
T90 Sequelae of injuries of head	0.658	0.342	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.657	0.343	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.657	0.343	0.000
S49 Other and unspecified injuries of shoulder and upper arm	0.657	0.343	0.000
V20-V29 Motorcycle rider injured in transport accident	0.657	0.343	0.000
S50 Superficial injury of forearm	0.657	0.343	0.000
D45 Polycythaemia vera	0.657	0.343	0.000
T78 Adverse effects, not elsewhere classified	0.656	0.344	0.000
G00 Bacterial meningitis, not elsewhere classified	0.654	0.346	0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care	0.654	0.346	0.000
G95.9 Disease of spinal cord, unspecified	0.653	0.347	0.000
W60 Contact with plant thorns and spines and sharp leaves	0.653	0.347	0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system	0.652	0.348	0.000
C70 Malignant neoplasm of meninges	0.652	0.348	0.000
C83.7 Burkitt's tumour	0.650	0.349	0.000
C83.6 Undifferentiated (diffuse)	0.650	0.349	0.000
C83.5 Lymphoblastic (diffuse)	0.650	0.349	0.000
C83.4 Immunoblastic (diffuse)	0.650	0.349	0.000
C83.2 Mixed small and large cell (diffuse)	0.650	0.349	0.000
C83.1 Small cleaved cell (diffuse)	0.650	0.349	0.000
D09 Carcinoma in situ of other and unspecified sites	0.649	0.351	0.000
G50-G59 Nerve, nerve root and plexus disorders	0.649	0.351	0.000
Q00-Q07 Congenital malformations of the nervous system	0.649	0.351	0.000
C67.8 Overlapping lesion of bladder	0.649	0.351	0.000
C67.7 Urachus	0.649	0.351	0.000
C67.3 Anterior wall of bladder	0.649	0.351	0.000
S52.1 Fracture of upper end of radius	0.648	0.351	0.000
S59 Other and unspecified injuries of forearm	0.648	0.352	0.000
S58 Traumatic amputation of forearm	0.648	0.352	0.000
S57 Crushing injury of forearm	0.648	0.352	0.000
S56 Injury of muscle and tendon at forearm level	0.648	0.352	0.000
S55 Injury of blood vessels at forearm level	0.648	0.352	0.000
S54 Injury of nerves at forearm level	0.648	0.352	0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow	0.648	0.352	0.000
C69 Malignant neoplasm of eye and adnexa	0.648	0.352	0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere	0.647	0.352	0.000
C60-C63 Malignant neoplasms of male genital organs	0.647	0.353	0.000
C49 Malignant neoplasm of other connective and soft tissue	0.647	0.353	0.000
H81 Disorders of vestibular function	0.645	0.355	0.000
C71.0 Cerebrum, except lobes and ventricles	0.644	0.355	0.000
G96 Other disorders of central nervous system	0.644	0.356	0.000
C82.6 Cutaneous follicle centre lymphoma	0.642	0.358	0.000
C82.5 Diffuse follicle centre lymphoma	0.642	0.358	0.000
C82.4 Follicular lymphoma grade IIIb	0.642	0.358	0.000
C82.3 Follicular lymphoma grade IIIa	0.642	0.358	0.000
C82.1 Mixed small cleaved and large cell, follicular	0.642	0.358	0.000
C82.0 Small cleaved cell, follicular	0.642	0.358	0.000
D40.1 Testis	0.641	0.359	0.000
Y65 Other misadventures during surgical and medical care	0.639	0.361	0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified	0.639	0.361	0.000
S19.9 Unspecified injury of neck	0.639	0.361	0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.638	0.362	0.000
H90-H95 Other disorders of ear	0.638	0.362	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.637	0.363	0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes	0.636	0.364	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.635	0.365	0.000
S11.8 Open wound of other parts of neck	0.635	0.365	0.000
W18 Other fall on same level	0.631	0.369	0.000
J32.9 Chronic sinusitis, unspecified	0.631	0.369	0.000
T23 Burn and corrosion of wrist and hand	0.630	0.370	0.000
Q60 Renal agenesis and other reduction defects of kidney	0.629	0.371	0.000
G61.9 Inflammatory polyneuropathy, unspecified	0.629	0.371	0.000
G61.8 Other inflammatory polyneuropathies	0.629	0.371	0.000
G61.1 Serum neuropathy	0.629	0.371	0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma	0.629	0.371	0.000
G63.8 Polyneuropathy in other diseases classified elsewhere	0.628	0.372	0.000
G63.6 Polyneuropathy in other musculoskeletal disorders	0.628	0.372	0.000
G63.5 Polyneuropathy in systemic connective tissue disorders	0.628	0.372	0.000
G63.4 Polyneuropathy in nutritional deficiency	0.628	0.372	0.000
G63.3 Polyneuropathy in other endocrine and metabolic diseases	0.628	0.372	0.000
G63.1 Polyneuropathy in neoplastic disease	0.628	0.372	0.000
G63.0 Polyneuropathy in infectious and parasitic diseases classified elsewhere	0.628	0.372	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.628	0.372	0.000
Q35-Q37 Cleft lip and cleft palate	0.628	0.372	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.628	0.372	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.628	0.372	0.000
S13.6 Sprain and strain of joints and ligaments of other and unspecified parts of neck	0.628	0.372	0.000
T98.3 Sequelae of complications of surgical and medical care, not elsewhere classified	0.628	0.372	0.000
W49 Exposure to other and unspecified inanimate mechanical forces	0.625	0.375	0.000
J38.2 Nodules of vocal cords	0.625	0.375	0.000
Y91 Evidence of alcohol involvement determined by level of intoxication	0.623	0.377	0.000
Y90 Evidence of alcohol involvement determined by blood alcohol level	0.623	0.377	0.000
Y98 Lifestyle-related condition	0.623	0.377	0.000
Y97 Environmental-pollution-related condition	0.623	0.377	0.000
Y96 Work-related condition	0.623	0.377	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.623	0.377	0.000
T83.1 Mechanical complication of other urinary devices and implants	0.623	0.377	0.000
G82.4 Spastic tetraplegia	0.622	0.378	0.000
G82.3 Flaccid tetraplegia	0.622	0.378	0.000
G82.0 Flaccid paraplegia	0.622	0.378	0.000
S40.8 Other superficial injuries of shoulder and upper arm	0.622	0.378	0.000
S40.7 Multiple superficial injuries of shoulder and upper arm	0.622	0.378	0.000
W44.0 Home	0.621	0.379	0.000
G40.5 Special epileptic syndromes	0.620	0.380	0.000
G40.4 Other generalised epilepsy and epileptic syndromes	0.620	0.380	0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset	0.620	0.380	0.000
H61.2 Impacted cerumen	0.620	0.380	0.000
D80-D89 Certain disorders involving the immune mechanism	0.619	0.381	0.000
G45 Transient cerebral ischaemic attacks and related syndromes	0.619	0.381	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.619	0.381	0.000
G06 Intracranial and intraspinal abscess and granuloma	0.618	0.381	0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere	0.618	0.381	0.000
G09 Sequelae of inflammatory diseases of central nervous system	0.618	0.381	0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis	0.618	0.381	0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere	0.618	0.381	0.000
G01 Meningitis in bacterial diseases classified elsewhere	0.618	0.381	0.000
X49 Accidental poisoning by and exposure to other and unspecified chemicals and noxious substances	0.619	0.381	0.000
J32.4 Chronic pansinusitis	0.618	0.382	0.000
G97.9 Postprocedural disorder of nervous system, unspecified	0.618	0.382	0.000
G97.2 Intracranial hypotension following ventricular shunting	0.618	0.382	0.000
G97.0 Cerebrospinal fluid leak from spinal puncture	0.618	0.382	0.000
T91.3 Sequelae of injury of spinal cord	0.617	0.383	0.000
J03 Acute tonsillitis	0.616	0.384	0.000
G40.8 Other epilepsy	0.616	0.384	0.000
X45 Accidental poisoning by and exposure to alcohol	0.615	0.385	0.000
J35.1 Hypertrophy of tonsils	0.615	0.385	0.000
G93.1 Anoxic brain damage, not elsewhere classified	0.615	0.385	0.000
S52.5 Fracture of lower end of radius	0.614	0.386	0.000
S51.7 Multiple open wounds of forearm	0.613	0.387	0.000
G90.0 Idiopathic peripheral autonomic neuropathy	0.613	0.387	0.000
S70-S79 Injuries to the hip and thigh	0.612	0.388	0.000
C02 Malignant neoplasm of other and unspecified parts of tongue	0.612	0.388	0.000
G31.9 Degenerative disease of nervous system, unspecified	0.612	0.388	0.000
T95 Sequelae of burns, corrosions and frostbite	0.611	0.388	0.000
T94 Sequelae of injuries involving multiple and unspecified body regions	0.611	0.388	0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.611	0.388	0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.611	0.388	0.000
H81.1 Benign paroxysmal vertigo	0.611	0.388	0.000
L40-L45 Papulosquamous disorders	0.611	0.389	0.000
S14.1 Other and unspecified injuries of cervical spinal cord	0.611	0.389	0.000
W08 Fall involving other furniture	0.610	0.390	0.000
C84.9 Mature T/NK-cell lymphoma, unspecified	0.609	0.391	0.000
C84.8 Cutaneous T-cell lymphoma, unspecified	0.609	0.391	0.000
C84.7 Anaplastic large cell lymphoma, ALK-negative	0.609	0.391	0.000
C84.6 Anaplastic large cell lymphoma, ALK-positive	0.609	0.391	0.000
C84.5 Other and unspecified T-cell lymphomas	0.609	0.391	0.000
C84.3 Lymphoepithelioid lymphoma	0.609	0.391	0.000
C84.2 T-zone lymphoma	0.609	0.391	0.000
C84.1 Sezary's diease	0.609	0.391	0.000
C84.0 Mycosis fungoides	0.609	0.391	0.000
S52.8 Fracture of other parts of forearm	0.609	0.391	0.000
W17 Other fall from one level to another	0.608	0.392	0.000
C71.8 Overlapping lesion of brain	0.606	0.394	0.000
C71.7 Brain stem	0.606	0.394	0.000
C71.6 Cerebellum	0.606	0.394	0.000
C71.5 Cerebral ventricle	0.606	0.394	0.000
C71.4 Occipital lobe	0.606	0.394	0.000
D44.9 Endocrine gland, unspecified	0.606	0.394	0.000
D44.8 Pluriglandular involvement	0.606	0.394	0.000
D44.7 Aortic body and other paraganglia	0.606	0.394	0.000
D44.6 Carotid body	0.606	0.394	0.000
D44.5 Pineal gland	0.606	0.394	0.000
D44.4 Craniopharyngeal duct	0.606	0.394	0.000
D44.2 Parathyroid gland	0.606	0.394	0.000
D44.1 Adrenal gland	0.606	0.394	0.000
T75 Effects of other external causes	0.605	0.395	0.000
T74 Maltreatment syndromes	0.605	0.395	0.000
T73 Effects of other deprivation	0.605	0.395	0.000
T70 Effects of air pressure and water pressure	0.605	0.395	0.000
T69 Other effects of reduced temperature	0.605	0.395	0.000
T67 Effects of heat and light	0.605	0.395	0.000
T71 Asphyxiation	0.605	0.395	0.000
T66 Unspecified effects of radiation	0.605	0.395	0.000
Y54.5 Other diuretics	0.605	0.395	0.000
Y49 Psychotropic drugs, not elsewhere classified	0.605	0.395	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.603	0.397	0.000
D40.0 Prostate	0.601	0.399	0.000
S51.0 Open wound of elbow	0.601	0.399	0.000
G44 Other headache syndromes	0.601	0.399	0.000
G94.8 Other specified disorders of brain in diseases classified elsewhere	0.601	0.399	0.000
G94.1 Hydrocephalus in neoplastic disease	0.601	0.399	0.000
G94.0 Hydrocephalus in infectious and parasitic diseases classified elsewhere	0.601	0.399	0.000
Y85.9 Sequelae of other and unspecified transport accidents	0.601	0.399	0.000
C67.5 Bladder neck	0.600	0.400	0.000
D48.1 Connective and other soft tissue	0.599	0.401	0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases	0.599	0.401	0.000
J33.0 Polyp of nasal cavity	0.597	0.403	0.000
C90.0 Multiple myeloma	0.597	0.403	0.000
Y48 Anaesthetics and therapeutic gases	0.597	0.403	0.000
T86.9 Failure and rejection of unspecified transplanted organ and tissue	0.594	0.406	0.000
T86.4 Liver transplant failure and rejection	0.594	0.406	0.000
T86.3 Heart-lung transplant failure and rejection	0.594	0.406	0.000
T86.2 Heart transplant failure and rejection	0.594	0.406	0.000
C71.1 Frontal lobe	0.593	0.407	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.593	0.407	0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis	0.593	0.407	0.000
J91 Pleural effusion in conditions classified elsewhere	0.593	0.407	0.000
S96 Injury of muscle and tendon at ankle and foot level	0.592	0.408	0.000
D05.0 Lobular carcinoma in situ	0.591	0.409	0.000
G93.4 Encephalopathy, unspecified	0.591	0.409	0.000
T93 Sequelae of injuries of lower limb	0.591	0.409	0.000
W19.4 Street and highway	0.590	0.410	0.000
W16 Diving or jumping into water causing injury other than drowning or submersion	0.590	0.410	0.000
W15 Fall from cliff	0.590	0.410	0.000
W14 Fall from tree	0.590	0.410	0.000
W12 Fall on and from scaffolding	0.590	0.410	0.000
W11 Fall on and from ladder	0.590	0.410	0.000
W09 Fall involving playground equipment	0.590	0.410	0.000
W05 Fall involving wheelchair	0.590	0.410	0.000
W04 Fall while being carried or supported by other persons	0.590	0.410	0.000
W03 Other fall on same level due to collision with, or pushing by, another person	0.590	0.410	0.000
W01 Fall on same level from slipping, tripping and stumbling	0.590	0.410	0.000
W00 Fall on same level involving ice and snow	0.590	0.410	0.000
W64 Exposure to other and unspecified animate mechanical forces	0.590	0.410	0.000
W59 Bitten or crushed by other reptiles	0.590	0.410	0.000
W58 Bitten or struck by crocodile or alligator	0.590	0.410	0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods	0.590	0.410	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations