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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12231974
log Bayes Factor = 6.07834
Chromosome 12   position 67,095,378  (GRCh37) Explore rs12231974 on Ensembl!
Variant rs12231974 is part of Cluster X0125

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
1.000 0.000 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
1.000 0.000 0.000
Chapter XX External causes of morbidity and mortality
1.000 0.000 0.000
Chapter II Neoplasms
0.999 0.001 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.995 0.005 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.992 0.008 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.992 0.008 0.000
E83 Disorders of mineral metabolism
0.991 0.009 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.991 0.009 0.000
Y52 Agents primarily affecting the cardiovascular system
0.989 0.011 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.985 0.015 0.000
H53-H54 Visual disturbances and blindness
0.980 0.020 0.000
Chapter VII Diseases of the eye and adnexa
0.980 0.020 0.000
H53 Visual disturbances
0.979 0.021 0.000
D00-D09 In situ neoplasms
0.978 0.022 0.000
C90.0 Multiple myeloma
0.976 0.024 0.000
Chapter VI Diseases of the nervous system
0.975 0.025 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.972 0.028 0.000
C85.9 Non-Hodgkin's lymphoma, unspecified type
0.968 0.032 0.000
O48 Prolonged pregnancy
0.967 0.033 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.966 0.034 0.000
G40-G47 Episodic and paroxysmal disorders
0.966 0.034 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.964 0.036 0.000
H53.1 Subjective visual disturbances
0.959 0.041 0.000
E87.5 Hyperkalaemia
0.957 0.043 0.000
H53.0 Amblyopia ex anopsia
0.955 0.045 0.000
G40 Epilepsy
0.954 0.046 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.949 0.051 0.000
E83.3 Disorders of phosphorus metabolism
0.947 0.053 0.000
C91 Lymphoid leukaemia
0.946 0.054 0.000
E83.4 Disorders of magnesium metabolism
0.944 0.056 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.941 0.059 0.000
E87.6 Hypokalaemia
0.940 0.060 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.940 0.060 0.000
Y40 Systemic antibiotics
0.937 0.063 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.933 0.067 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.932 0.068 0.000
G43 Migraine
0.926 0.074 0.000
D06 Carcinoma in situ of cervix uteri
0.926 0.074 0.000
Chapter V Mental and behavioural disorders
0.925 0.075 0.000
E80.4 Gilbert's syndrome
0.916 0.084 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.911 0.089 0.000
C91.1 Chronic lymphocytic leukaemia
0.907 0.093 0.000
G40.9 Epilepsy, unspecified
0.906 0.094 0.000
E83.1 Disorders of iron metabolism
0.903 0.097 0.000
X60-X84 Intentional self-harm
0.903 0.097 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.896 0.104 0.000
D09 Carcinoma in situ of other and unspecified sites
0.894 0.106 0.000
G70-G73 Diseases of myoneural junction and muscle
0.891 0.108 0.000
H54 Blindness and low vision
0.891 0.109 0.000
D06.9 Cervix, unspecified
0.889 0.111 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.888 0.112 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.888 0.112 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.880 0.120 0.000
C88 Malignant immunoproliferative diseases
0.880 0.120 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.877 0.123 0.000
Q60-Q64 Congenital malformations of the urinary system
0.874 0.126 0.000
X20-X29 Contact with venomous animals and plants
0.869 0.131 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.857 0.143 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.856 0.144 0.000
C83.3 Large cell (diffuse)
0.853 0.147 0.000
Y40.0 Penicillins
0.852 0.148 0.000
Y52.9 Other and unspecified agents primarily affecting the cardiovascular system
0.852 0.148 0.000
G43.9 Migraine, unspecified
0.850 0.150 0.000
C50-C50 Malignant neoplasm of breast
0.849 0.151 0.000
C90.2 Plasmacytoma, extramedullary
0.849 0.151 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.848 0.152 0.000
F20 Schizophrenia
0.842 0.158 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.841 0.159 0.000
G43.1 Migraine with aura [classical migraine]
0.835 0.165 0.000
H00 Hordeolum and chalazion
0.835 0.165 0.000
C85.1 B-cell lymphoma, unspecified
0.834 0.166 0.000
D09.0 Bladder
0.834 0.166 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.833 0.167 0.000
E87.0 Hyperosmolality and hypernatraemia
0.829 0.171 0.000
Q00-Q07 Congenital malformations of the nervous system
0.822 0.178 0.000
Q80-Q89 Other congenital malformations
0.820 0.180 0.000
H00.1 Chalazion
0.820 0.180 0.000
Y52.7 Peripheral vasodilators
0.820 0.180 0.000
Y59 Other and unspecified vaccines and biological substances
0.817 0.183 0.000
H53.8 Other visual disturbances
0.814 0.186 0.000
Chapter XXII Codes for special purposes
0.813 0.186 0.000
E87.7 Fluid overload
0.812 0.188 0.000
Y40.1 Cefalosporins and other -lactam antibiotics
0.810 0.190 0.000
O41 Other disorders of amniotic fluid and membranes
0.810 0.190 0.000
C90.1 Plasma cell leukaemia
0.805 0.195 0.000
D05 Carcinoma in situ of breast
0.803 0.197 0.000
F20.9 Schizophrenia, unspecified
0.802 0.198 0.000
H54.7 Unspecified visual loss
0.800 0.199 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.800 0.200 0.000
V10-V19 Pedal cyclist injured in transport accident
0.799 0.200 0.000
Y51.5 Predominantly Beta-adrenoreceptor agonists, not elsewhere classified
0.799 0.201 0.000
Y42.7 Androgens and anabolic congeners
0.799 0.201 0.000
W00-W19 Falls
0.797 0.203 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.793 0.207 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.793 0.207 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.791 0.209 0.000
H54.9 Unspecified visual impairment (binocular)
0.788 0.212 0.000
C82.4 Follicular lymphoma grade IIIb
0.788 0.212 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.787 0.213 0.000
Y48 Anaesthetics and therapeutic gases
0.787 0.213 0.000
G72 Other myopathies
0.787 0.213 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.785 0.215 0.000
Q27 Other congenital malformations of peripheral vascular system
0.783 0.217 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.780 0.220 0.000
G71 Primary disorders of muscles
0.779 0.221 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.778 0.222 0.000
F60-F69 Disorders of adult personality and behaviour
0.778 0.222 0.000
Q63 Other congenital malformations of kidney
0.777 0.223 0.000
X23 Contact with hornets, wasps and bees
0.775 0.225 0.000
X60 Intentional self-poisoning by and exposure to nonopioid analgesics, antipyretics and antirheumatics
0.775 0.225 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.775 0.225 0.000
H01 Other inflammation of eyelid
0.773 0.227 0.000
E87.3 Alkalosis
0.773 0.227 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.772 0.228 0.000
Y40.9 Systemic antibiotic, unspecified
0.771 0.229 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.771 0.229 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.770 0.230 0.000
C93 Monocytic leukaemia
0.768 0.232 0.000
Q25 Congenital malformations of great arteries
0.767 0.232 0.000
V40-V49 Car occupant injured in transport accident
0.767 0.233 0.000
O47 False labour
0.766 0.234 0.000
Y57 Other and unspecified drugs and medicaments
0.766 0.234 0.000
O32.1 Maternal care for breech presentation
0.765 0.235 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.764 0.236 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.760 0.240 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.755 0.245 0.000
Q24 Other congenital malformations of heart
0.750 0.250 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.749 0.251 0.000
G40.8 Other epilepsy
0.748 0.251 0.000
H10-H13 Disorders of conjunctiva
0.748 0.252 0.000
H53.2 Diplopia
0.748 0.252 0.000
Chapter I Certain infectious and parasitic diseases
0.748 0.252 0.000
O32.2 Maternal care for transverse and oblique lie
0.748 0.252 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.746 0.254 0.000
C50 Malignant neoplasm of breast
0.742 0.258 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.741 0.259 0.000
E83.5 Disorders of calcium metabolism
0.741 0.259 0.000
G90-G99 Other disorders of the nervous system
0.738 0.262 0.000
V80-V89 Other land transport accidents
0.738 0.262 0.000
C91.9 Lymphoid leukaemia, unspecified
0.737 0.263 0.000
Y00-Y09 Assault
0.735 0.265 0.000
X65 Intentional self-poisoning by and exposure to alcohol
0.734 0.266 0.000
O30 Multiple gestation
0.732 0.268 0.000
Q50-Q56 Congenital malformations of genital organs
0.731 0.269 0.000
H53.4 Visual field defects
0.728 0.272 0.000
W50-W64 Exposure to animate mechanical forces
0.727 0.272 0.000
A30-A49 Other bacterial diseases
0.727 0.273 0.000
Q64 Other congenital malformations of urinary system
0.725 0.275 0.000
G47 Sleep disorders
0.724 0.276 0.000
E87.2 Acidosis
0.724 0.276 0.000
C82.3 Follicular lymphoma grade IIIa
0.722 0.278 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.721 0.279 0.000
Q38 Other congenital malformations of tongue, mouth and pharynx
0.720 0.280 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.720 0.280 0.000
G30-G32 Other degenerative diseases of the nervous system
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.717 0.283 0.000
C95 Leukaemia of unspecified cell type
0.717 0.283 0.000
C94 Other leukaemias of specified cell type
0.717 0.283 0.000
C86 Other specified types of T/NK-cell lymphoma
0.717 0.283 0.000
Y58 Bacterial vaccines
0.717 0.283 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.717 0.283 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.717 0.283 0.000
Y35-Y36 Legal intervention and operations of war
0.717 0.283 0.000
Y10-Y34 Event of undetermined intent
0.717 0.283 0.000
X85-X99 Assault
0.717 0.283 0.000
X30-X39 Exposure to forces of nature
0.717 0.283 0.000
X10-X19 Contact with heat and hot substances
0.717 0.283 0.000
X00-X09 Exposure to smoke, fire and flames
0.717 0.283 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.717 0.283 0.000
W75-W84 Other accidental threats to breathing
0.717 0.283 0.000
W65-W74 Accidental drowning and submersion
0.717 0.283 0.000
V98-V99 Other and unspecified transport accidents
0.717 0.283 0.000
V95-V97 Air and space transport accidents
0.717 0.283 0.000
V90-V94 Water transport accidents
0.717 0.283 0.000
V70-V79 Bus occupant injured in transport accident
0.717 0.283 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.717 0.283 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.717 0.283 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.717 0.283 0.000
V01-V09 Pedestrian injured in transport accident
0.717 0.283 0.000
X50-X57 Overexertion, travel and privation
0.716 0.284 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.715 0.285 0.000
Q35-Q37 Cleft lip and cleft palate
0.714 0.286 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.714 0.286 0.000
C83.0 Small cell (diffuse)
0.714 0.286 0.000
O32.8 Maternal care for other malpresentation of foetus
0.713 0.287 0.000
O32.9 Maternal care for malpresentation of foetus, unspecified
0.713 0.287 0.000
E84 Cystic fibrosis
0.713 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.713 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.713 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.713 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.713 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.713 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.713 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.713 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.713 0.287 0.000
G72.9 Myopathy, unspecified
0.712 0.288 0.000
Q21 Congenital malformations of cardiac septa
0.712 0.288 0.000
C90.3 Solitary plasmacytoma
0.711 0.289 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.711 0.289 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.711 0.289 0.000
E83.8 Other disorders of mineral metabolism
0.711 0.289 0.000
E83.2 Disorders of zinc metabolism
0.711 0.289 0.000
E83.0 Disorders of copper metabolism
0.711 0.289 0.000
E87.4 Mixed disorder of acid-base balance
0.711 0.289 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.710 0.290 0.000
O33 Maternal care for known or suspected disproportion
0.710 0.290 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.710 0.290 0.000
Q23 Congenital malformations of aortic and mitral valves
0.710 0.290 0.000
Y52.8 Antivaricose drugs, including sclerosing agents
0.709 0.291 0.000
Y52.6 Antihyperlipidaemic and antiarteriosclerotic drugs
0.709 0.291 0.000
Y52.0 Cardiac-stimulant glycosides and drugs of similar action
0.709 0.291 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.709 0.291 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.709 0.291 0.000
X23.9 Unspecified place
0.708 0.292 0.000
A41 Other septicaemia
0.706 0.294 0.000
C85.2 Mediastinal (thymic) large B-cell lymphoma
0.706 0.294 0.000
C85.0 Lymphosarcoma
0.706 0.294 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.706 0.294 0.000
H53.6 Night blindness
0.702 0.298 0.000
H53.5 Colour vision deficiencies
0.702 0.298 0.000
H53.3 Other disorders of binocular vision
0.702 0.298 0.000
D05.1 Intraductal carcinoma in situ
0.702 0.298 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.701 0.299 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.701 0.299 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.699 0.300 0.000
Q05 Spina bifida
0.698 0.302 0.000
E73 Lactose intolerance
0.698 0.302 0.000
Y51.9 Other and unspecified drugs primarily affecting the autonomic nervous system
0.697 0.303 0.000
Y51.8 Centrally acting and adrenergic-neuron-blocking agents, not elsewhere classified
0.697 0.303 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.697 0.303 0.000
Y51.4 Predominantly Alpha-adrenoreceptor agonists, not elsewhere classified
0.697 0.303 0.000
Y51.3 Other parasympatholytics [anticholinergics and antimuscarinics] and spasmolytics, not elsewhere classified
0.697 0.303 0.000
Y51.2 Ganglionic blocking drugs, not elsewhere classified
0.697 0.303 0.000
Y51.1 Other parasympathomimetics [cholinergics]
0.697 0.303 0.000
Y51.0 Anticholinesterase agents
0.697 0.303 0.000
Y46.2 Hydantoin derivatives
0.696 0.304 0.000
E85 Amyloidosis
0.695 0.305 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.694 0.306 0.000
C82.2 Large cell, follicular
0.694 0.306 0.000
A41.9 Septicaemia, unspecified
0.694 0.306 0.000
O45 Premature separation of placenta [abruptio placentae]
0.693 0.307 0.000
O31 Complications specific to multiple gestation
0.693 0.307 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.692 0.307 0.000
E74 Other disorders of carbohydrate metabolism
0.692 0.308 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.692 0.308 0.000
D37.1 Stomach
0.692 0.308 0.000
D37.9 Digestive organ, unspecified
0.691 0.309 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.691 0.309 0.000
Q63.1 Lobulated, fused and horseshoe kidney
0.689 0.311 0.000
C50.2 Upper-inner quadrant of breast
0.688 0.312 0.000
O47.1 False labour at or after 37 completed weeks of gestation
0.687 0.313 0.000
V20-V29 Motorcycle rider injured in transport accident
0.687 0.313 0.000
F20.0 Paranoid schizophrenia
0.686 0.314 0.000
O85-O92 Complications predominantly related to the puerperium
0.686 0.314 0.000
Y59.3 Immunoglobulin
0.685 0.314 0.000
O42 Premature rupture of membranes
0.685 0.315 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.684 0.316 0.000
G40.5 Special epileptic syndromes
0.684 0.316 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.684 0.316 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.684 0.316 0.000
Q89 Other congenital malformations, not elsewhere classified
0.684 0.316 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.683 0.317 0.000
X60.8 Other specified place
0.683 0.317 0.000
H54.0 Blindness, both eyes
0.683 0.317 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.682 0.317 0.000
F29 Unspecified nonorganic psychosis
0.682 0.318 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.682 0.318 0.000
G71.0 Muscular dystrophy
0.682 0.318 0.000
E80.7 Disorder of bilirubin metabolism, unspecified
0.680 0.320 0.000
E80.6 Other disorders of bilirubin metabolism
0.680 0.320 0.000
E80.5 Crigler-Najjar syndrome
0.680 0.320 0.000
E80.3 Defects of catalase and peroxydase
0.680 0.320 0.000
E80.2 Other porphyria
0.680 0.320 0.000
E80.1 Porphyria cutanea tarda
0.680 0.320 0.000
E80.0 Hereditary erythropoietic porphyria
0.680 0.320 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.679 0.321 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.678 0.322 0.000
C91.7 Other lymphoid leukaemia
0.678 0.322 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.678 0.322 0.000
C91.5 Adult T-cell leukaemia
0.678 0.322 0.000
C91.3 Prolymphocytic leukaemia
0.678 0.322 0.000
C91.2 Subacute lymphocytic leukaemia
0.678 0.322 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.678 0.322 0.000
Y46.4 Iminostilbenes
0.677 0.323 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.677 0.323 0.000
H01.8 Other specified inflammation of eyelid
0.677 0.323 0.000
C91.0 Acute lymphoblastic leukaemia
0.676 0.324 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.672 0.328 0.000
Q28 Other congenital malformations of circulatory system
0.672 0.328 0.000
Y40.7 Antifungal antibiotics, systemically used
0.672 0.328 0.000
Y40.6 Rifamycins
0.672 0.328 0.000
Y40.5 Aminoglycosides
0.672 0.328 0.000
Y40.4 Tetracyclines
0.672 0.328 0.000
Y40.2 Chloramphenicol group
0.672 0.328 0.000
C83.7 Burkitt's tumour
0.669 0.331 0.000
C83.6 Undifferentiated (diffuse)
0.669 0.331 0.000
C83.5 Lymphoblastic (diffuse)
0.669 0.331 0.000
C83.4 Immunoblastic (diffuse)
0.669 0.331 0.000
C83.2 Mixed small and large cell (diffuse)
0.669 0.331 0.000
C82.7 Other types of follicular non-Hodgkin's lymphoma
0.669 0.331 0.000
Q26 Congenital malformations of great veins
0.669 0.331 0.000
Q22 Congenital malformations of pulmonary and tricuspid valves
0.669 0.331 0.000
Q20 Congenital malformations of cardiac chambers and connexions
0.669 0.331 0.000
C82.9 Follicular non-Hodgkin's lymphoma, unspecified
0.668 0.332 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.667 0.333 0.000
C82.1 Mixed small cleaved and large cell, follicular
0.667 0.333 0.000
Y40.3 Macrolides
0.666 0.334 0.000
G00 Bacterial meningitis, not elsewhere classified
0.665 0.335 0.000
G43.3 Complicated migraine
0.664 0.336 0.000
G43.2 Status migrainosus
0.664 0.336 0.000
G43.0 Migraine without aura [common migraine]
0.664 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.664 0.336 0.000
D06.7 Other parts of cervix
0.664 0.336 0.000
D06.1 Exocervix
0.664 0.336 0.000
D06.0 Endocervix
0.664 0.336 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.663 0.337 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.663 0.337 0.000
F70-F79 Mental retardation
0.663 0.337 0.000
W17 Other fall from one level to another
0.663 0.337 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.662 0.338 0.000
Y52.1 Calcium-channel blockers
0.662 0.338 0.000
D03 Melanoma in situ
0.661 0.338 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.660 0.340 0.000
Q27.9 Congenital malformation of peripheral vascular system, unspecified
0.659 0.341 0.000
O41.0 Oligohydramnios
0.659 0.341 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.659 0.341 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.658 0.342 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.658 0.342 0.000
C85.7 Other specified types of non-Hodgkin's lymphoma
0.657 0.343 0.000
O32.3 Maternal care for face, brow and chin presentation
0.657 0.343 0.000
X62.9 Unspecified place
0.657 0.343 0.000
C50.9 Breast, unspecified
0.656 0.344 0.000
W07 Fall involving chair
0.654 0.346 0.000
C82.6 Cutaneous follicle centre lymphoma
0.653 0.347 0.000
C82.5 Diffuse follicle centre lymphoma
0.653 0.347 0.000
C82.0 Small cleaved cell, follicular
0.653 0.347 0.000
D37.7 Other digestive organs
0.653 0.347 0.000
C12 Malignant neoplasm of pyriform sinus
0.653 0.347 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.652 0.348 0.000
F25 Schizoaffective disorders
0.651 0.349 0.000
E40-E46 Malnutrition
0.650 0.349 0.000
D00.1 Oesophagus
0.650 0.350 0.000
F80-F89 Disorders of psychological development
0.650 0.350 0.000
E88 Other metabolic disorders
0.649 0.350 0.000
X84 Intentional self-harm by unspecified means
0.647 0.352 0.000
X83 Intentional self-harm by other specified means
0.647 0.352 0.000
X82 Intentional self-harm by crashing of motor vehicle
0.647 0.352 0.000
X81 Intentional self-harm by jumping or lying before moving object
0.647 0.352 0.000
X80 Intentional self-harm by jumping from a high place
0.647 0.352 0.000
X79 Intentional self-harm by blunt object
0.647 0.352 0.000
X77 Intentional self-harm by steam, hot vapours and hot objects
0.647 0.352 0.000
X76 Intentional self-harm by smoke, fire and flames
0.647 0.352 0.000
X75 Intentional self-harm by explosive material
0.647 0.352 0.000
X74 Intentional self-harm by other and unspecified firearm discharge
0.647 0.352 0.000
X73 Intentional self-harm by rifle, shotgun and larger firearm discharge
0.647 0.352 0.000
X72 Intentional self-harm by handgun discharge
0.647 0.352 0.000
X71 Intentional self-harm by drowning and submersion
0.647 0.352 0.000
X70 Intentional self-harm by hanging, strangulation and suffocation
0.647 0.352 0.000
X69 Intentional self-poisoning by and exposure to other and unspecified chemicals and noxious substances
0.647 0.352 0.000
X67 Intentional self-poisoning by and exposure to other gases and vapours
0.647 0.352 0.000
X66 Intentional self-poisoning by and exposure to organic solvents and halogenated hydrocarbons and their vapours
0.647 0.352 0.000
X64 Intentional self-poisoning by and exposure to other and unspecified drugs, medicaments and biological substances
0.647 0.352 0.000
X61 Intentional self-poisoning by and exposure to antiepileptic, sedative-hypnotic, anti-Parkinsonism and psychotropic drugs, not elsewhere classified
0.647 0.352 0.000
F43 Reaction to severe stress, and adjustment disorders
0.647 0.353 0.000
G43.8 Other migraine
0.646 0.354 0.000
A46 Erysipelas
0.645 0.355 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.644 0.356 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.644 0.356 0.000
Q85 Phakomatoses, not elsewhere classified
0.643 0.356 0.000
Y44 Agents primarily affecting blood constituents
0.642 0.358 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.642 0.358 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.641 0.359 0.000
D09.9 Carcinoma in situ, unspecified
0.641 0.359 0.000
D09.7 Carcinoma in situ of other specified sites
0.641 0.359 0.000
D09.3 Thyroid and other endocrine glands
0.641 0.359 0.000
D09.2 Eye
0.641 0.359 0.000
D09.1 Other and unspecified urinary organs
0.641 0.359 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.640 0.360 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.639 0.361 0.000
G73 Disorders of myoneural junction and muscle in diseases classified elsewhere
0.639 0.361 0.000
D46 Myelodysplastic syndromes
0.639 0.361 0.000
H54.6 Unqualified visual loss, one eye
0.639 0.361 0.000
H54.5 Low vision, one eye
0.639 0.361 0.000
H54.3 Unqualified visual loss, both eyes
0.639 0.361 0.000
H54.2 Low vision, both eyes
0.639 0.361 0.000
H54.1 Blindness, one eye, low vision, other eye
0.639 0.361 0.000
F10.2 Dependence syndrome
0.639 0.361 0.000
E50-E64 Other nutritional deficiencies
0.638 0.362 0.000
Y42.5 Other oestrogens and progestogens
0.637 0.362 0.000
O32.6 Maternal care for compound presentation
0.637 0.363 0.000
O32.4 Maternal care for high head at term
0.637 0.363 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.637 0.363 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.637 0.363 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.637 0.363 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.637 0.363 0.000
F64 Gender identity disorders
0.636 0.364 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.636 0.364 0.000
Y48.4 Anaesthetic, unspecified
0.634 0.365 0.000
Q96 Turner's syndrome
0.634 0.365 0.000
Y49.0 Tricyclic and tetracyclic antidepressants
0.634 0.366 0.000
H43-H45 Disorders of vitreous body and globe
0.634 0.366 0.000
C50.8 Overlapping lesion of breast
0.633 0.367 0.000
H01.0 Blepharitis
0.633 0.367 0.000
G04.8 Other encephalitis, myelitis and encephalomyelitis
0.633 0.367 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.633 0.367 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.633 0.367 0.000
F28 Other nonorganic psychotic disorders
0.631 0.369 0.000
F24 Induced delusional disorder
0.631 0.369 0.000
F21 Schizotypal disorder
0.631 0.369 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.631 0.369 0.000
C88.9 Malignant immunoproliferative disease, unspecified
0.631 0.369 0.000
C88.7 Other malignant immunoproliferative diseases
0.631 0.369 0.000
C88.4 Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue [MALT-lymphoma]
0.631 0.369 0.000
C88.3 Immunoproliferative small intestinal disease
0.631 0.369 0.000
C88.2 Gamma heavy chain disease
0.631 0.369 0.000
C88.1 Alpha heavy chain disease
0.631 0.369 0.000
O40 Polyhydramnios
0.630 0.370 0.000
Y45.1 Salicylates
0.630 0.370 0.000
D37.4 Colon
0.630 0.370 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.629 0.371 0.000
Y42.9 Other and unspecified hormone antagonists
0.629 0.371 0.000
Y42.4 Oral contraceptives
0.629 0.371 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.629 0.371 0.000
Y42.2 Antithyroid drugs
0.629 0.371 0.000
Y42.1 Thyroid hormones and substitutes
0.629 0.371 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.628 0.372 0.000
F23 Acute and transient psychotic disorders
0.628 0.372 0.000
C83.1 Small cleaved cell (diffuse)
0.628 0.372 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.627 0.373 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.627 0.373 0.000
H55-H59 Other disorders of eye and adnexa
0.627 0.373 0.000
Q25.0 Patent ductus arteriosus
0.626 0.374 0.000
G90 Disorders of autonomic nervous system
0.625 0.375 0.000
Q38.7 Pharyngeal pouch
0.623 0.376 0.000
X29 Contact with unspecified venomous animal or plant
0.623 0.377 0.000
X28 Contact with other specified venomous plants
0.623 0.377 0.000
X27 Contact with other specified venomous animals
0.623 0.377 0.000
X26 Contact with venomous marine animals and plants
0.623 0.377 0.000
X25 Contact with other specified venomous arthropods
0.623 0.377 0.000
X24 Contact with centipedes and venomous millipedes (tropical)
0.623 0.377 0.000
X22 Contact with scorpions
0.623 0.377 0.000
X21 Contact with venomous spiders
0.623 0.377 0.000
X20 Contact with venomous snakes and lizards
0.623 0.377 0.000
C51-C58 Malignant neoplasms of female genital organs
0.623 0.377 0.000
Q39 Congenital malformations of oesophagus
0.623 0.377 0.000
Q24.9 Congenital malformation of the heart, unspecified
0.620 0.380 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.619 0.381 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.619 0.381 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.618 0.382 0.000
Q64.3 Other atresia and stenosis of urethra and bladder neck
0.617 0.383 0.000
G41 Status epilepticus
0.617 0.383 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.616 0.384 0.000
Q79 Congenital malformations of musculoskeletal system, not elsewhere classified
0.616 0.384 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.616 0.384 0.000
C91.4 Hairy-cell leukaemia
0.614 0.386 0.000
F60 Specific personality disorders
0.614 0.386 0.000
Q45 Other congenital malformations of digestive system
0.614 0.386 0.000
Q42 Congenital absence, atresia and stenosis of large intestine
0.614 0.386 0.000
Q41 Congenital absence, atresia and stenosis of small intestine
0.614 0.386 0.000
Q40 Other congenital malformations of upper alimentary tract
0.614 0.386 0.000
X65.8 Other specified place
0.612 0.388 0.000
Y45.5 4-Aminophenol derivatives
0.610 0.390 0.000
Q05.9 Spina bifida, unspecified
0.610 0.390 0.000
Y46.8 Antispasticity drugs
0.608 0.392 0.000
Y46.7 Anti-Parkinsonism drugs
0.608 0.392 0.000
Y46.6 Other and unspecified antiepileptics
0.608 0.392 0.000
Y46.5 Valproic acid
0.608 0.392 0.000
Y46.3 Deoxybarbiturates
0.608 0.392 0.000
Y46.1 Oxazolidinediones
0.608 0.392 0.000
Y46.0 Succinimides
0.608 0.392 0.000
C84.5 Other and unspecified T-cell lymphomas
0.608 0.392 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.608 0.392 0.000
G91 Hydrocephalus
0.608 0.392 0.000
C41 Malignant neoplasm of bone and articular cartilage of other and unspecified sites
0.607 0.393 0.000
O44 Placenta praevia
0.606 0.394 0.000
W10 Fall on and from stairs and steps
0.605 0.395 0.000
F20.8 Other schizophrenia
0.604 0.396 0.000
F20.6 Simple schizophrenia
0.604 0.396 0.000
F20.5 Residual schizophrenia
0.604 0.396 0.000
F20.4 Postschizophrenic depression
0.604 0.396 0.000
F20.3 Undifferentiated schizophrenia
0.604 0.396 0.000
F20.2 Catatonic schizophrenia
0.604 0.396 0.000
F20.1 Hebephrenic schizophrenia
0.604 0.396 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.603 0.396 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.603 0.397 0.000
C92 Myeloid leukaemia
0.603 0.397 0.000
Q63.0 Accessory kidney
0.602 0.398 0.000
C93.1 Chronic monocytic leukaemia
0.601 0.399 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.601 0.399 0.000
Y45.2 Propionic acid derivatives
0.600 0.400 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.600 0.400 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.600 0.400 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.598 0.402 0.000
O34.7 Maternal care for abnormality of vulva and perineum
0.597 0.402 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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