TreeWAS – Variant ID: rs12252129

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
R31 Unspecified haematuria	0.002	0.998
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.002	0.998
R30-R39 Symptoms and signs involving the urinary system	0.002	0.998
# Top node	0.002	0.998
Z72.1 Alcohol use	0.001	0.998
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.001	0.998
Chapter XXI Factors influencing health status and contact with health services	0.001	0.998
Z72 Problems related to lifestyle	0.001	0.998
Z70-Z76 Persons encountering health services in other circumstances	0.001	0.998
Z51.2 Other chemotherapy	0.001	0.998
R10 Abdominal and pelvic pain	0.001	0.998
Z40-Z54 Persons encountering health services for specific procedures and health care	0.001	0.998
Chapter XIV Diseases of the genitourinary system	0.001	0.998
Z51 Other medical care	0.001	0.998
R50-R69 General symptoms and signs	0.001	0.998
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.001	0.998
R95-R99 Ill-defined and unknown causes of mortality	0.001	0.998
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.001	0.998
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis	0.001	0.998
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.001	0.998
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.001	0.998
R47-R49 Symptoms and signs involving speech and voice	0.001	0.998
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.001	0.998
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.998
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue	0.001	0.998
Chapter V Mental and behavioural disorders	0.001	0.998
R10.1 Pain localised to upper abdomen	0.001	0.999
R39 Other symptoms and signs involving the urinary system	0.001	0.999
R30 Pain associated with micturition	0.001	0.999
R36 Urethral discharge	0.001	0.999
R35 Polyuria	0.001	0.999
R34 Anuria and oliguria	0.001	0.999
R33 Retention of urine	0.001	0.999
R32 Unspecified urinary incontinence	0.001	0.999
N40-N51 Diseases of male genital organs	0.001	0.999
R00-R09 Symptoms and signs involving the circulatory and respiratory systems	0.001	0.999
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.001	0.999
R10.4 Other and unspecified abdominal pain	0.001	0.999
D60-D64 Aplastic and other anaemias	0.001	0.999
Chapter XXII Codes for special purposes	0.001	0.999
Chapter XX External causes of morbidity and mortality	0.001	0.999
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.001	0.999
Chapter XVI Certain conditions originating in the perinatal period	0.001	0.999
Chapter XV Pregnancy, childbirth and the puerperium	0.001	0.999
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.001	0.999
Chapter XII Diseases of the skin and subcutaneous tissue	0.001	0.999
Chapter VIII Diseases of the ear and mastoid process	0.001	0.999
Chapter VII Diseases of the eye and adnexa	0.001	0.999
Chapter VI Diseases of the nervous system	0.001	0.999
Chapter II Neoplasms	0.001	0.999
Chapter I Certain infectious and parasitic diseases	0.001	0.999
R19 Other symptoms and signs involving the digestive system and abdomen	0.001	0.999
R16 Hepatomegaly and splenomegaly, not elsewhere classified	0.001	0.999
R18 Ascites	0.001	0.999
R17 Unspecified jaundice	0.001	0.999
R15 Faecal incontinence	0.001	0.999
R14 Flatulence and related conditions	0.001	0.999
R13 Dysphagia	0.001	0.999
R12 Heartburn	0.001	0.999
R11 Nausea and vomiting	0.001	0.999
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.001	0.999
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.001	0.999
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.001	0.999
Z00-Z13 Persons encountering health services for examination and investigation	0.001	0.999
Z72.9 Problem related to lifestyle, unspecified	0.001	0.999
Z72.8 Other problems related to lifestyle	0.001	0.999
Z72.6 Gambling and betting	0.001	0.999
Z72.5 High-risk sexual behaviour	0.001	0.999
Z72.4 Inappropriate diet and eating habits	0.001	0.999
Z72.3 Lack of physical exercise	0.001	0.999
Z72.2 Drug use	0.001	0.999
Z72.0 Tobacco use	0.001	0.999
Z76 Persons encountering health services in other circumstances	0.001	0.999
Z75 Problems related to medical facilities and other health care	0.001	0.999
Z74 Problems related to care-provider dependency	0.001	0.999
Z73 Problems related to life-management difficulty	0.001	0.999
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.001	0.999
Z70 Counselling related to sexual attitude, behaviour and orientation	0.001	0.999
Chapter X Diseases of the respiratory system	0.001	0.999
Chapter IV Endocrine, nutritional and metabolic diseases	0.001	0.999
R10.3 Pain localised to other parts of lower abdomen	0.001	0.999
R10.2 Pelvic and perineal pain	0.001	0.999
R10.0 Acute abdomen	0.001	0.999
D64 Other anaemias	0.001	0.999
N40 Hyperplasia of prostate	0.001	0.999
R69 Unknown and unspecified causes of morbidity	0.001	0.999
F30-F39 Mood [affective] disorders	0.001	0.999
Chapter XI Diseases of the digestive system	0.001	0.999
D64.9 Anaemia, unspecified	0.001	0.999
Z54 Convalescence	0.001	0.999
Z52 Donors of organs and tissues	0.001	0.999
Z50 Care involving use of rehabilitation procedures	0.001	0.999
Z49 Care involving dialysis	0.001	0.999
Z48 Other surgical follow-up care	0.001	0.999
Z47 Other orthopaedic follow-up care	0.001	0.999
Z46 Fitting and adjustment of other devices	0.001	0.999
Z45 Adjustment and management of implanted device	0.001	0.999
Z44 Fitting and adjustment of external prosthetic device	0.001	0.999
Z43 Attention to artificial openings	0.001	0.999
Z42 Follow-up care involving plastic surgery	0.001	0.999
Z41 Procedures for purposes other than remedying health state	0.001	0.999
Z40 Prophylactic surgery	0.001	0.999
N99-N99 Other disorders of the genitourinary system	0.001	0.999
N80-N98 Noninflammatory disorders of female genital tract	0.001	0.999
N70-N77 Inflammatory diseases of female pelvic organs	0.001	0.999
N60-N64 Disorders of breast	0.001	0.999
N30-N39 Other diseases of urinary system	0.001	0.999
N25-N29 Other disorders of kidney and ureter	0.001	0.999
N20-N23 Urolithiasis	0.001	0.999
N17-N19 Renal failure	0.001	0.999
N10-N16 Renal tubulo-interstitial diseases	0.001	0.999
N00-N08 Glomerular diseases	0.001	0.999
Z51.9 Medical care, unspecified	0.001	0.999
Z51.8 Other specified medical care	0.001	0.999
Z51.6 Desensitisation to allergens	0.001	0.999
Z51.5 Palliative care	0.001	0.999
Z51.4 Preparatory care for treatment, not elsewhere classified	0.001	0.999
Z51.3 Blood transfusion without reported diagnosis	0.001	0.999
Z51.1 Chemotherapy session for neoplasm	0.001	0.999
Z51.0 Radiotherapy session	0.001	0.999
R68 Other general symptoms and signs	0.001	0.999
R65 Systemic Inflammatory Response Syndrome [SIRS]	0.001	0.999
R63 Symptoms and signs concerning food and fluid intake	0.001	0.999
R62 Lack of expected normal physiological development	0.001	0.999
R61 Hyperhidrosis	0.001	0.999
R60 Oedema, not elsewhere classified	0.001	0.999
R59 Enlarged lymph nodes	0.001	0.999
R57 Shock, not elsewhere classified	0.001	0.999
R56 Convulsions, not elsewhere classified	0.001	0.999
R52 Pain, not elsewhere classified	0.001	0.999
R50 Fever of unknown origin	0.001	0.999
R64 Cachexia	0.001	0.999
R58 Haemorrhage, not elsewhere classified	0.001	0.999
R55 Syncope and collapse	0.001	0.999
R54 Senility	0.001	0.999
R53 Malaise and fatigue	0.001	0.999
R51 Headache	0.001	0.999
Z53 Persons encountering health services for specifie procedures, not carried out	0.001	0.999
D80-D89 Certain disorders involving the immune mechanism	0.001	0.999
D70-D77 Other diseases of blood and blood-forming organs	0.001	0.999
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.001	0.999
D55-D59 Haemolytic anaemias	0.001	0.999
D50-D53 Nutritional anaemias	0.001	0.999
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.001	0.999
R23 Other skin changes	0.001	0.999
R22 Localised swelling, mass and lump of skin and subcutaneous tissue	0.001	0.999
R20 Disturbances of skin sensation	0.001	0.999
R21 Rash and other nonspecific skin eruption	0.001	0.999
R29 Other symptoms and signs involving the nervous and musculoskeletal systems	0.001	0.999
R27 Other lack of coordination	0.001	0.999
R26 Abnormalities of gait and mobility	0.001	0.999
R25 Abnormal involuntary movements	0.001	0.999
R46 Symptoms and signs involving appearance and behaviour	0.001	0.999
R45 Symptoms and signs involving emotional state	0.001	0.999
R44 Other symptoms and signs involving general sensations and perceptions	0.001	0.999
R43 Disturbances of smell and taste	0.001	0.999
R41 Other symptoms and signs involving cognitive functions and awareness	0.001	0.999
R40 Somnolence, stupor and coma	0.001	0.999
R42 Dizziness and giddiness	0.001	0.999
R49 Voice disturbances	0.001	0.999
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.001	0.999
R47 Speech disturbances, not elsewhere classified	0.001	0.999
R79 Other abnormal findings of blood chemistry	0.001	0.999
R78 Findings of drugs and other substances, not normally found in blood	0.001	0.999
R77 Other abnormalities of plasma proteins	0.001	0.999
R76 Other abnormal immunological findings in serum	0.001	0.999
R74 Abnormal serum enzyme levels	0.001	0.999
R73 Elevated blood glucose level	0.001	0.999
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity	0.001	0.999
R75 Laboratory evidence of human immunodeficiency virus [HIV]	0.001	0.999
R72 Abnormality of white blood cells, not elsewhere classified	0.001	0.999
R71 Abnormality of red blood cells	0.001	0.999
R82 Other abnormal findings in urine	0.001	0.999
R81 Glycosuria	0.001	0.999
R80 Isolated proteinuria	0.001	0.999
R89 Abnormal findings in specimens from other organs, systems and tissues	0.001	0.999
R87 Abnormal findings in specimens from female genital organs	0.001	0.999
R86 Abnormal findings in specimens from male genital organs	0.001	0.999
R85 Abnormal findings in specimens from digestive organs and abdominal cavity	0.001	0.999
R84 Abnormal findings in specimens from respiratory organs and thorax	0.001	0.999
R83 Abnormal findings in cerebrospinal fluid	0.001	0.999
R94 Abnormal results of function studies	0.001	0.999
R93 Abnormal findings on diagnostic imaging of other body structures	0.001	0.999
R90 Abnormal findings on diagnostic imaging of central nervous system	0.001	0.999
R92 Abnormal findings on diagnostic imaging of breast	0.001	0.999
R91 Abnormal findings on diagnostic imaging of lung	0.001	0.999
R96 Other sudden death, cause unknown	0.001	0.999
R95 Sudden infant death syndrome	0.001	0.999
R99 Other ill-defined and unspecified causes of mortality	0.001	0.999
R98 Unattended death	0.001	0.999
F99-F99 Unspecified mental disorder	0.001	0.999
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.001	0.999
F80-F89 Disorders of psychological development	0.001	0.999
F70-F79 Mental retardation	0.001	0.999
F60-F69 Disorders of adult personality and behaviour	0.001	0.999
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.001	0.999
F40-F48 Neurotic, stress-related and somatoform disorders	0.001	0.999
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.001	0.999
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.001	0.999
F00-F09 Organic, including symptomatic, mental disorders	0.001	0.999
R30.9 Painful micturition, unspecified	0.001	0.999
R30.1 Vesical tenesmus	0.001	0.999
R30.0 Dysuria	0.001	0.999
R39.8 Other and unspecified symptoms and signs involving the urinary system	0.001	0.999
R39.2 Extrarenal uraemia	0.001	0.999
R39.1 Other difficulties with micturition	0.001	0.999
R39.0 Extravasation of urine	0.001	0.999
Chapter IX Diseases of the circulatory system	0.001	0.999
F32 Depressive episode	0.001	0.999
N51 Disorders of male genital organs in diseases classified elsewhere	0.001	0.999
N50 Other disorders of male genital organs	0.001	0.999
N49 Inflammatory disorders of male genital organs, not elsewhere classified	0.001	0.999
N48 Other disorders of penis	0.001	0.999
N45 Orchitis and epididymitis	0.001	0.999
N43 Hydrocele and spermatocele	0.001	0.999
N42 Other disorders of prostate	0.001	0.999
N41 Inflammatory diseases of prostate	0.001	0.999
N47 Redundant prepuce, phimosis and paraphimosis	0.001	0.999
N46 Male infertility	0.001	0.999
N44 Torsion of testis	0.001	0.999
R09 Other symptoms and signs involving the circulatory and respiratory systems	0.001	0.999
R06 Abnormalities of breathing	0.001	0.999
R04 Haemorrhage from respiratory passages	0.001	0.999
R03 Abnormal blood-pressure reading, without diagnosis	0.001	0.999
R01 Cardiac murmurs and other cardiac sounds	0.001	0.999
R00 Abnormalities of heart beat	0.001	0.999
R05 Cough	0.001	0.999
R02 Gangrene, not elsewhere classified	0.001	0.999
B99-B99 Other infectious diseases	0.001	0.999
B95-B98 Bacterial, viral and other infectious agents	0.001	0.999
B90-B94 Sequelae of infectious and parasitic diseases	0.001	0.999
B85-B89 Pediculosis, acariasis and other infestations	0.001	0.999
B65-B83 Helminthiases	0.001	0.999
B50-B64 Protozoal diseases	0.001	0.999
B35-B49 Mycoses	0.001	0.999
B25-B34 Other viral diseases	0.001	0.999
B20-B24 Human immunodeficiency virus [HIV] disease	0.001	0.999
B15-B19 Viral hepatitis	0.001	0.999
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.001	0.999
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.001	0.999
A80-A89 Viral infections of the central nervous system	0.001	0.999
A75-A79 Rickettsioses	0.001	0.999
A70-A74 Other diseases caused by chlamydiae	0.001	0.999
A65-A69 Other spirochaetal diseases	0.001	0.999
A50-A64 Infections with a predominantly sexual mode of transmission	0.001	0.999
A30-A49 Other bacterial diseases	0.001	0.999
A20-A28 Certain zoonotic bacterial diseases	0.001	0.999
A15-A19 Tuberculosis	0.001	0.999
A00-A09 Intestinal infectious diseases	0.001	0.999
D37-D48 Neoplasms of uncertain or unknown behaviour	0.001	0.999
D10-D36 Benign neoplasms	0.001	0.999
D00-D09 In situ neoplasms	0.001	0.999
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.001	0.999
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.001	0.999
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.001	0.999
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.001	0.999
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.001	0.999
C64-C68 Malignant neoplasms of urinary tract	0.001	0.999
C60-C63 Malignant neoplasms of male genital organs	0.001	0.999
C51-C58 Malignant neoplasms of female genital organs	0.001	0.999
C50-C50 Malignant neoplasm of breast	0.001	0.999
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.001	0.999
C43-C44 Melanoma and other malignant neoplasms of skin	0.001	0.999
C40-C41 Malignant neoplasms of bone and articular cartilage	0.001	0.999
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.001	0.999
C15-C26 Malignant neoplasms of digestive organs	0.001	0.999
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.001	0.999
G90-G99 Other disorders of the nervous system	0.001	0.999
G80-G83 Cerebral palsy and other paralytic syndromes	0.001	0.999
G70-G73 Diseases of myoneural junction and muscle	0.001	0.999
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.001	0.999
G50-G59 Nerve, nerve root and plexus disorders	0.001	0.999
G40-G47 Episodic and paroxysmal disorders	0.001	0.999
G35-G37 Demyelinating diseases of the central nervous system	0.001	0.999
G30-G32 Other degenerative diseases of the nervous system	0.001	0.999
G20-G26 Extrapyramidal and movement disorders	0.001	0.999
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.001	0.999
G00-G09 Inflammatory diseases of the central nervous system	0.001	0.999
H55-H59 Other disorders of eye and adnexa	0.001	0.999
H53-H54 Visual disturbances and blindness	0.001	0.999
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.001	0.999
H46-H48 Disorders of optic nerve and visual pathways	0.001	0.999
H43-H45 Disorders of vitreous body and globe	0.001	0.999
H40-H42 Glaucoma	0.001	0.999
H30-H36 Disorders of choroid and retina	0.001	0.999
H25-H28 Disorders of lens	0.001	0.999
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.001	0.999
H10-H13 Disorders of conjunctiva	0.001	0.999
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.001	0.999
H90-H95 Other disorders of ear	0.001	0.999
H80-H83 Diseases of inner ear	0.001	0.999
H65-H75 Diseases of middle ear and mastoid	0.001	0.999
H60-H62 Diseases of external ear	0.001	0.999
L80-L99 Other disorders of the skin and subcutaneous tissue	0.001	0.999
L60-L75 Disorders of skin appendages	0.001	0.999
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.001	0.999
L50-L54 Urticaria and erythema	0.001	0.999
L40-L45 Papulosquamous disorders	0.001	0.999
L20-L30 Dermatitis and eczema	0.001	0.999
L10-L14 Bullous disorders	0.001	0.999
L00-L08 Infections of the skin and subcutaneous tissue	0.001	0.999
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.001	0.999
M91-M94 Chondropathies	0.001	0.999
M86-M90 Other osteopathies	0.001	0.999
M80-M85 Disorders of bone density and structure	0.001	0.999
M70-M79 Other soft tissue disorders	0.001	0.999
M65-M68 Disorders of synovium and tendon	0.001	0.999
M60-M63 Disorders of muscles	0.001	0.999
M50-M54 Other dorsopathies	0.001	0.999
M45-M49 Spondylopathies	0.001	0.999
M40-M43 Deforming dorsopathies	0.001	0.999
M20-M25 Other joint disorders	0.001	0.999
M15-M19 Arthrosis	0.001	0.999
M05-M14 Inflammatory polyarthropathies	0.001	0.999
M00-M03 Infectious arthropathies	0.001	0.999
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.001	0.999
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.001	0.999
T79-T79 Certain early complications of trauma	0.001	0.999
T66-T78 Other and unspecified effects of external causes	0.001	0.999
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.001	0.999
T36-T50 Poisoning by drugs, medicaments and biological substances	0.001	0.999
T33-T35 Frostbite	0.001	0.999
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.001	0.999
T26-T28 Burns and corrosions confined to eye and internal organs	0.001	0.999
T20-T25 Burns and corrosions of external body surface, specified by site	0.001	0.999
T15-T19 Effects of foreign body entering through natural orifice	0.001	0.999
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.001	0.999
T00-T07 Injuries involving multiple body regions	0.001	0.999
S90-S99 Injuries to the ankle and foot	0.001	0.999
S80-S89 Injuries to the knee and lower leg	0.001	0.999
S70-S79 Injuries to the hip and thigh	0.001	0.999
S60-S69 Injuries to the wrist and hand	0.001	0.999
S50-S59 Injuries to the elbow and forearm	0.001	0.999
S40-S49 Injuries to the shoulder and upper arm	0.001	0.999
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.001	0.999
S20-S29 Injuries to the thorax	0.001	0.999
S10-S19 Injuries to the neck	0.001	0.999
S00-S09 Injuries to the head	0.001	0.999
O94-O99 Other obstetric conditions, not elsewhere classified	0.001	0.999
O85-O92 Complications predominantly related to the puerperium	0.001	0.999
O80-O84 Delivery	0.001	0.999
O60-O75 Complications of labour and delivery	0.001	0.999
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.001	0.999
O20-O29 Other maternal disorders predominantly related to pregnancy	0.001	0.999
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.001	0.999
O00-O08 Pregnancy with abortive outcome	0.001	0.999
P90-P96 Other disorders originating in the perinatal period	0.001	0.999
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn	0.001	0.999
P75-P78 Digestive system disorders of fetus and newborn	0.001	0.999
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn	0.001	0.999
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn	0.001	0.999
P35-P39 Infections specific to the perinatal period	0.001	0.999
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period	0.001	0.999
P10-P15 Birth trauma	0.001	0.999
P05-P08 Disorders related to length of gestation and fetal growth	0.001	0.999
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery	0.001	0.999
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.001	0.999
Q80-Q89 Other congenital malformations	0.001	0.999
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.001	0.999
Q60-Q64 Congenital malformations of the urinary system	0.001	0.999
Q50-Q56 Congenital malformations of genital organs	0.001	0.999
Q38-Q45 Other congenital malformations of the digestive system	0.001	0.999
Q35-Q37 Cleft lip and cleft palate	0.001	0.999
Q30-Q34 Congenital malformations of the respiratory system	0.001	0.999
Q20-Q28 Congenital malformations of the circulatory system	0.001	0.999
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.001	0.999
Q00-Q07 Congenital malformations of the nervous system	0.001	0.999
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.001	0.999
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.001	0.999
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.001	0.999
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.001	0.999
Y60-Y69 Misadventures to patients during surgical and medical care	0.001	0.999
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.001	0.999
Y35-Y36 Legal intervention and operations of war	0.001	0.999
Y10-Y34 Event of undetermined intent	0.001	0.999
Y00-Y09 Assault	0.001	0.999
X85-X99 Assault	0.001	0.999
X60-X84 Intentional self-harm	0.001	0.999
X58-X59 Accidental exposure to other and unspecified factors	0.001	0.999
X50-X57 Overexertion, travel and privation	0.001	0.999
X40-X49 Accidental poisoning by and exposure to noxious substances	0.001	0.999
X30-X39 Exposure to forces of nature	0.001	0.999
X20-X29 Contact with venomous animals and plants	0.001	0.999
X10-X19 Contact with heat and hot substances	0.001	0.999
X00-X09 Exposure to smoke, fire and flames	0.001	0.999
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.001	0.999
W75-W84 Other accidental threats to breathing	0.001	0.999
W65-W74 Accidental drowning and submersion	0.001	0.999
W50-W64 Exposure to animate mechanical forces	0.001	0.999
W20-W49 Exposure to inanimate mechanical forces	0.001	0.999
W00-W19 Falls	0.001	0.999
V98-V99 Other and unspecified transport accidents	0.001	0.999
V95-V97 Air and space transport accidents	0.001	0.999
V90-V94 Water transport accidents	0.001	0.999
V80-V89 Other land transport accidents	0.001	0.999
V70-V79 Bus occupant injured in transport accident	0.001	0.999
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.001	0.999
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.001	0.999
V40-V49 Car occupant injured in transport accident	0.001	0.999
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.001	0.999
V20-V29 Motorcycle rider injured in transport accident	0.001	0.999
V10-V19 Pedal cyclist injured in transport accident	0.001	0.999
V01-V09 Pedestrian injured in transport accident	0.001	0.999
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.001	0.999
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.001	0.999
R16.2 Hepatomegaly with splenomegaly, not elsewhere classified	0.001	0.999
R16.1 Splenomegaly, not elsewhere classified	0.001	0.999
R16.0 Hepatomegaly, not elsewhere classified	0.001	0.999
R19.8 Other specified symptoms and signs involving the digestive system and abdomen	0.001	0.999
R19.6 Halitosis	0.001	0.999
R19.5 Other fecal abnormalities	0.001	0.999
R19.4 Change in bowel habit	0.001	0.999
R19.3 Abdominal rigidity	0.001	0.999
R19.2 Visible peristalsis	0.001	0.999
R19.1 Abnormal bowel sounds	0.001	0.999
R19.0 Intra-abdominal and pelvic swelling, mass and lump	0.001	0.999
D63 Anaemia in chronic diseases classified elsewhere	0.001	0.999
D61 Other aplastic anaemias	0.001	0.999
D60 Acquired pure red cell aplasia [erythroblastopenia]	0.001	0.999
D62 Acute posthaemorrhagic anaemia	0.001	0.999
Z13 Special screening examination for other diseases and disorders	0.001	0.999
Z12 Special screening examination for neoplasms	0.001	0.999
Z11 Special screening examination for infectious and parasitic diseases	0.001	0.999
Z10 Routine general health check-up of defined subpopulation	0.001	0.999
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms	0.001	0.999
Z08 Follow-up examination after treatment for malignant neoplasm	0.001	0.999
Z04 Examination and observation for other reasons	0.001	0.999
Z03 Medical observation and evaluation for suspected diseases and conditions	0.001	0.999
Z02 Examination and encounter for administrative purposes	0.001	0.999
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis	0.001	0.999
Z00 General examination and investigation of persons without complaint or reported diagnosis	0.001	0.999
Z29 Need for other prophylactic measures	0.001	0.999
Z28 Immunisation not carried out	0.001	0.999
Z27 Need for immunisation against combinations of infectious diseases	0.001	0.999
Z26 Need for immunisation against other single infectious diseases	0.001	0.999
Z25 Need for immunisation against other single viral diseases	0.001	0.999
Z24 Need for immunisation against certain single viral diseases	0.001	0.999
Z23 Need for immunisation against single bacterial diseases	0.001	0.999
Z22 Carrier of infectious disease	0.001	0.999
Z20 Contact with and exposure to communicable diseases	0.001	0.999
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status	0.001	0.999
Z39 Postpartum care and examination	0.001	0.999
Z38 Liveborn infants according to place of birth	0.001	0.999
Z37 Outcome of delivery	0.001	0.999
Z36 Antenatal screening	0.001	0.999
Z35 Supervision of high-risk pregnancy	0.001	0.999
Z34 Supervision of normal pregnancy	0.001	0.999
Z32 Pregnancy examination and test	0.001	0.999
Z31 Procreative management	0.001	0.999
Z30 Contraceptive management	0.001	0.999
Z33 Pregnant state, incidental	0.001	0.999
Z65 Problems related to other psychosocial circumstances	0.001	0.999
Z64 Problems related to certain psychosocial circumstances	0.001	0.999
Z63 Other problems related to primary support group, including family circumstances	0.001	0.999
Z62 Other problems related to upbringing	0.001	0.999
Z61 Problems related to negative life events in childhood	0.001	0.999
Z60 Problems related to social environment	0.001	0.999
Z59 Problems related to housing and economic circumstances	0.001	0.999
Z58 Problems related to physical environment	0.001	0.999
Z57 Occupational exposure to risk-factors	0.001	0.999
Z56 Problems related to employment and unemployment	0.001	0.999
Z55 Problems related to education and literacy	0.001	0.999
F32.9 Depressive episode, unspecified	0.001	0.999
Z70.9 Sex counselling, unspecified	0.001	0.999
Z70.8 Other sex counselling	0.001	0.999
Z70.3 Counselling related to combined concerns regarding sexual attitude, behaviour and orientation	0.001	0.999
Z70.2 Counselling related to sexual behaviour and orientation of third party	0.001	0.999
Z70.1 Counselling related to patient's sexual behaviour and orientation	0.001	0.999
Z70.0 Counselling related to sexual attitude	0.001	0.999
Z71.9 Counselling, unspecified	0.001	0.999
Z71.8 Other specified counselling	0.001	0.999
Z71.7 Human immunodeficiency virus [HIV] counselling	0.001	0.999
Z71.6 Tobacco abuse counselling	0.001	0.999
Z71.5 Drug abuse counselling and surveillance	0.001	0.999
Z71.4 Alcohol abuse counselling and surveillance	0.001	0.999
Z71.3 Dietary counselling and surveillance	0.001	0.999
Z71.2 Person consulting for explanation of investigation findings	0.001	0.999
Z71.1 Person with feared complaint in whom no diagnosis is made	0.001	0.999
Z71.0 Person consulting on behalf of another person	0.001	0.999
Z73.9 Problem related to life-management difficulty, unspecified	0.001	0.999
Z73.8 Other problems related to life-management difficulty	0.001	0.999
Z73.6 Limitation of activities due to disability	0.001	0.999
Z73.5 Social role conflict, not elsewhere classified	0.001	0.999
Z73.4 Inadequate social skills, not elsewhere classified	0.001	0.999
Z73.3 Stress, not elsewhere classified	0.001	0.999
Z73.2 Lack of relaxation and leisure	0.001	0.999
Z73.1 Accentuation of personality traits	0.001	0.999
Z73.0 Burn-out	0.001	0.999
Z74.9 Problem related to care-provider dependency, unspecified	0.001	0.999
Z74.8 Other problems related to care-provider dependency	0.001	0.999
Z74.3 Need for continuous supervision	0.001	0.999
Z74.2 Need for assistance at home and no other household member able to render care	0.001	0.999
Z74.1 Need for assistance with personal care	0.001	0.999
Z74.0 Reduced mobility	0.001	0.999
Z75.9 Unspecified problem related to medical facilities and other health care	0.001	0.999
Z75.8 Other problems related to medical facilities and other health care	0.001	0.999
Z75.5 Holiday relief care	0.001	0.999
Z75.4 Unavailability and inaccessibility of other helping agencies	0.001	0.999
Z75.3 Unavailability and inaccessibility of health-care facilities	0.001	0.999
Z75.2 Other waiting period for investigation and treatment	0.001	0.999

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations