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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12257323
log Bayes Factor = 0.971239
Chromosome 10   position 22,494,143  (GRCh37) Explore rs12257323 on Ensembl!
Variant rs12257323 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter VII Diseases of the eye and adnexa
0.885 0.115 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.880 0.120 0.000
# Top node
0.877 0.123 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.873 0.127 0.000
O60-O75 Complications of labour and delivery
0.871 0.129 0.000
H30-H36 Disorders of choroid and retina
0.865 0.135 0.000
S00-S09 Injuries to the head
0.865 0.135 0.000
H33 Retinal detachments and breaks
0.856 0.144 0.000
H40-H42 Glaucoma
0.845 0.155 0.000
H33.0 Retinal detachment with retinal break
0.842 0.158 0.000
S40-S49 Injuries to the shoulder and upper arm
0.832 0.168 0.000
Chapter I Certain infectious and parasitic diseases
0.825 0.175 0.000
O70 Perineal laceration during delivery
0.817 0.183 0.000
Chapter VI Diseases of the nervous system
0.816 0.184 0.000
H40 Glaucoma
0.816 0.184 0.000
H25-H28 Disorders of lens
0.815 0.185 0.000
O72 Postpartum haemorrhage
0.809 0.190 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
S01 Open wound of head
0.799 0.201 0.000
Chapter XX External causes of morbidity and mortality
0.794 0.206 0.000
O70.0 First degree perineal laceration during delivery
0.787 0.213 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.782 0.218 0.000
S06 Intracranial injury
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.770 0.230 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.765 0.235 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.760 0.240 0.000
T78 Adverse effects, not elsewhere classified
0.755 0.245 0.000
B95-B98 Bacterial, viral and other infectious agents
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.745 0.255 0.000
H33.2 Serous retinal detachment
0.741 0.259 0.000
H26 Other cataract
0.733 0.267 0.000
S42 Fracture of shoulder and upper arm
0.731 0.269 0.000
H40.9 Glaucoma, unspecified
0.730 0.270 0.000
H40.2 Primary angle-closure glaucoma
0.722 0.278 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.719 0.281 0.000
Chapter V Mental and behavioural disorders
0.718 0.282 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.713 0.287 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.711 0.289 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.710 0.289 0.000
H55-H59 Other disorders of eye and adnexa
0.709 0.291 0.000
S20-S29 Injuries to the thorax
0.708 0.292 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.708 0.292 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.705 0.295 0.000
H26.9 Cataract, unspecified
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
Chapter XXII Codes for special purposes
0.697 0.303 0.000
O72.0 Third-stage haemorrhage
0.696 0.304 0.000
O72.1 Other immediate postpartum haemorrhage
0.694 0.306 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.688 0.312 0.000
S02 Fracture of skull and facial bones
0.687 0.313 0.000
G91 Hydrocephalus
0.685 0.315 0.000
S61 Open wound of wrist and hand
0.682 0.318 0.000
O63 Long labour
0.680 0.320 0.000
S40 Superficial injury of shoulder and upper arm
0.679 0.321 0.000
H10-H13 Disorders of conjunctiva
0.678 0.322 0.000
S42.2 Fracture of upper end of humerus
0.676 0.324 0.000
H25 Senile cataract
0.676 0.324 0.000
S05 Injury of eye and orbit
0.675 0.325 0.000
S01.9 Open wound of head, part unspecified
0.672 0.328 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.670 0.329 0.000
S09 Other and unspecified injuries of head
0.670 0.330 0.000
A00-A09 Intestinal infectious diseases
0.668 0.332 0.000
S90-S99 Injuries to the ankle and foot
0.667 0.333 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.666 0.334 0.000
V10-V19 Pedal cyclist injured in transport accident
0.662 0.338 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.661 0.339 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.661 0.339 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.660 0.340 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
S01.1 Open wound of eyelid and periocular area
0.659 0.341 0.000
S61.0 Open wound of finger(s) without damage to nail
0.659 0.341 0.000
S01.8 Open wound of other parts of head
0.656 0.344 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.655 0.345 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.653 0.347 0.000
O70.2 Third degree perineal laceration during delivery
0.651 0.349 0.000
H02 Other disorders of eyelid
0.646 0.354 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.645 0.354 0.000
Y40 Systemic antibiotics
0.645 0.355 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.645 0.355 0.000
O41 Other disorders of amniotic fluid and membranes
0.643 0.356 0.000
S80-S89 Injuries to the knee and lower leg
0.643 0.357 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.639 0.361 0.000
S01.2 Open wound of nose
0.639 0.361 0.000
T78.4 Allergy, unspecified
0.638 0.362 0.000
O66 Other obstructed labour
0.638 0.362 0.000
S42.20 Fracture of upper end of humerus (closed)
0.637 0.363 0.000
S06.3 Focal brain injury
0.635 0.365 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.635 0.365 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.633 0.367 0.000
O62 Abnormalities of forces of labour
0.631 0.369 0.000
T79-T79 Certain early complications of trauma
0.631 0.369 0.000
T33-T35 Frostbite
0.631 0.369 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.631 0.369 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.631 0.369 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.631 0.369 0.000
T00-T07 Injuries involving multiple body regions
0.631 0.369 0.000
S10-S19 Injuries to the neck
0.631 0.369 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.629 0.371 0.000
O36 Maternal care for other known or suspected foetal problems
0.629 0.371 0.000
H40.5 Glaucoma secondary to other eye disorders
0.628 0.372 0.000
B15-B19 Viral hepatitis
0.627 0.373 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.627 0.373 0.000
O85-O92 Complications predominantly related to the puerperium
0.626 0.374 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.626 0.374 0.000
O74 Complications of anaesthesia during labour and delivery
0.625 0.375 0.000
O73 Retained placenta and membranes, without haemorrhage
0.625 0.375 0.000
O71 Other obstetric trauma
0.625 0.375 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.625 0.375 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.625 0.375 0.000
O61 Failed induction of labour
0.625 0.375 0.000
O60 Preterm delivery
0.625 0.375 0.000
Y52 Agents primarily affecting the cardiovascular system
0.624 0.376 0.000
B35-B49 Mycoses
0.623 0.377 0.000
G20-G26 Extrapyramidal and movement disorders
0.623 0.377 0.000
S43.0 Dislocation of shoulder joint
0.623 0.377 0.000
G70-G73 Diseases of myoneural junction and muscle
0.623 0.377 0.000
Y43 Primarily systemic agents
0.621 0.379 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.620 0.380 0.000
H31 Other disorders of choroid
0.620 0.380 0.000
H30 Chorioretinal inflammation
0.620 0.380 0.000
S08 Traumatic amputation of part of head
0.620 0.380 0.000
S07 Crushing injury of head
0.620 0.380 0.000
S04 Injury of cranial nerves
0.620 0.380 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.620 0.380 0.000
H33.3 Retinal breaks without detachment
0.619 0.381 0.000
H40.0 Glaucoma suspect
0.619 0.381 0.000
H40.1 Primary open-angle glaucoma
0.616 0.384 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.615 0.385 0.000
H33.5 Other retinal detachments
0.614 0.386 0.000
H33.4 Traction detachment of retina
0.614 0.386 0.000
H33.1 Retinoschisis and retinal cysts
0.614 0.386 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.614 0.386 0.000
S06.2 Diffuse brain injury
0.613 0.387 0.000
S06.6 Traumatic subarachnoid haemorrhage
0.613 0.387 0.000
H34 Retinal vascular occlusions
0.611 0.389 0.000
H35 Other retinal disorders
0.610 0.390 0.000
S00 Superficial injury of head
0.610 0.390 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.608 0.392 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.606 0.394 0.000
H42 Glaucoma in diseases classified elsewhere
0.605 0.394 0.000
T78.3 Angioneurotic oedema
0.604 0.395 0.000
S50-S59 Injuries to the elbow and forearm
0.601 0.399 0.000
W20-W49 Exposure to inanimate mechanical forces
0.598 0.402 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.597 0.403 0.000
S48 Traumatic amputation of shoulder and upper arm
0.597 0.403 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.597 0.403 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.597 0.403 0.000
S44 Injury of nerves at shoulder and upper arm level
0.597 0.403 0.000
S41 Open wound of shoulder and upper arm
0.597 0.403 0.000
S47 Crushing injury of shoulder and upper arm
0.597 0.403 0.000
T78.2 Anaphylactic shock, unspecified
0.595 0.405 0.000
H43-H45 Disorders of vitreous body and globe
0.595 0.405 0.000
O47 False labour
0.593 0.407 0.000
Y57 Other and unspecified drugs and medicaments
0.593 0.407 0.000
H01 Other inflammation of eyelid
0.592 0.408 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.592 0.408 0.000
B99-B99 Other infectious diseases
0.591 0.409 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.591 0.409 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.591 0.409 0.000
B65-B83 Helminthiases
0.591 0.409 0.000
B50-B64 Protozoal diseases
0.591 0.409 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.591 0.409 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.591 0.409 0.000
A80-A89 Viral infections of the central nervous system
0.591 0.409 0.000
A75-A79 Rickettsioses
0.591 0.409 0.000
A70-A74 Other diseases caused by chlamydiae
0.591 0.409 0.000
A65-A69 Other spirochaetal diseases
0.591 0.409 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.591 0.409 0.000
A20-A28 Certain zoonotic bacterial diseases
0.591 0.409 0.000
A15-A19 Tuberculosis
0.591 0.409 0.000
O64.1 Obstructed labour due to breech presentation
0.591 0.409 0.000
S70-S79 Injuries to the hip and thigh
0.590 0.410 0.000
S06.5 Traumatic subdural haemorrhage
0.590 0.410 0.000
G93 Other disorders of brain
0.586 0.414 0.000
O70.9 Perineal laceration during delivery, unspecified
0.586 0.414 0.000
O70.3 Fourth degree perineal laceration during delivery
0.586 0.414 0.000
G91.9 Hydrocephalus, unspecified
0.585 0.415 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.585 0.415 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.585 0.415 0.000
H40.8 Other glaucoma
0.585 0.415 0.000
H40.6 Glaucoma secondary to drugs
0.585 0.415 0.000
H40.4 Glaucoma secondary to eye inflammation
0.585 0.415 0.000
H40.3 Glaucoma secondary to eye trauma
0.585 0.415 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.585 0.415 0.000
H27 Other disorders of lens
0.585 0.415 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.583 0.417 0.000
H57 Other disorders of eye and adnexa
0.582 0.418 0.000
G30-G32 Other degenerative diseases of the nervous system
0.581 0.419 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.581 0.419 0.000
O72.3 Postpartum coagulation defects
0.580 0.419 0.000
T18 Foreign body in alimentary tract
0.579 0.421 0.000
T75 Effects of other external causes
0.579 0.421 0.000
T74 Maltreatment syndromes
0.579 0.421 0.000
T73 Effects of other deprivation
0.579 0.421 0.000
T70 Effects of air pressure and water pressure
0.579 0.421 0.000
T69 Other effects of reduced temperature
0.579 0.421 0.000
T67 Effects of heat and light
0.579 0.421 0.000
T71 Asphyxiation
0.579 0.421 0.000
T68 Hypothermia
0.579 0.421 0.000
T66 Unspecified effects of radiation
0.579 0.421 0.000
V20-V29 Motorcycle rider injured in transport accident
0.578 0.421 0.000
H04 Disorders of lachrymal system
0.578 0.422 0.000
S01.3 Open wound of ear
0.578 0.422 0.000
B25-B34 Other viral diseases
0.576 0.424 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.576 0.424 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.575 0.425 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.574 0.426 0.000
H25.0 Senile incipient cataract
0.574 0.426 0.000
G95 Other diseases of spinal cord
0.573 0.427 0.000
S01.7 Multiple open wounds of head
0.573 0.427 0.000
S01.4 Open wound of cheek and temporomandibular area
0.573 0.427 0.000
F80-F89 Disorders of psychological development
0.573 0.427 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.572 0.428 0.000
O75.2 Pyrexia during labour, not elsewhere classified
0.570 0.430 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.570 0.430 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.569 0.430 0.000
Y35-Y36 Legal intervention and operations of war
0.569 0.430 0.000
Y10-Y34 Event of undetermined intent
0.569 0.430 0.000
Y00-Y09 Assault
0.569 0.430 0.000
X85-X99 Assault
0.569 0.430 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.569 0.430 0.000
X50-X57 Overexertion, travel and privation
0.569 0.430 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.569 0.430 0.000
X30-X39 Exposure to forces of nature
0.569 0.430 0.000
X20-X29 Contact with venomous animals and plants
0.569 0.430 0.000
X10-X19 Contact with heat and hot substances
0.569 0.430 0.000
X00-X09 Exposure to smoke, fire and flames
0.569 0.430 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.569 0.430 0.000
W75-W84 Other accidental threats to breathing
0.569 0.430 0.000
W65-W74 Accidental drowning and submersion
0.569 0.430 0.000
W50-W64 Exposure to animate mechanical forces
0.569 0.430 0.000
V98-V99 Other and unspecified transport accidents
0.569 0.430 0.000
V95-V97 Air and space transport accidents
0.569 0.430 0.000
V90-V94 Water transport accidents
0.569 0.430 0.000
V80-V89 Other land transport accidents
0.569 0.430 0.000
V70-V79 Bus occupant injured in transport accident
0.569 0.430 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.569 0.430 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.569 0.430 0.000
V40-V49 Car occupant injured in transport accident
0.569 0.430 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.569 0.430 0.000
V01-V09 Pedestrian injured in transport accident
0.569 0.430 0.000
A04 Other bacterial intestinal infections
0.568 0.432 0.000
S27 Injury of other and unspecified intrathoracic organs
0.568 0.432 0.000
Chapter X Diseases of the respiratory system
0.567 0.433 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.567 0.433 0.000
G35 Multiple sclerosis
0.566 0.434 0.000
G91.1 Obstructive hydrocephalus
0.566 0.434 0.000
O32.1 Maternal care for breech presentation
0.564 0.436 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.564 0.436 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.562 0.438 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.562 0.438 0.000
Y40.0 Penicillins
0.562 0.438 0.000
O45 Premature separation of placenta [abruptio placentae]
0.561 0.439 0.000
O44 Placenta praevia
0.561 0.439 0.000
O43 Placental disorders
0.561 0.439 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.561 0.439 0.000
O33 Maternal care for known or suspected disproportion
0.561 0.439 0.000
O31 Complications specific to multiple gestation
0.561 0.439 0.000
O40 Polyhydramnios
0.561 0.439 0.000
H02.9 Disorder of eyelid, unspecified
0.560 0.440 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.560 0.440 0.000
O63.9 Long labour, unspecified
0.559 0.441 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.557 0.443 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.556 0.444 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.556 0.444 0.000
S06.9 Intracranial injury, unspecified
0.555 0.444 0.000
S06.8 Other intracranial injuries
0.555 0.444 0.000
S06.7 Intracranial injury with prolonged coma
0.555 0.444 0.000
S06.4 Epidural haemorrhage
0.555 0.444 0.000
S06.1 Traumatic cerebral oedema
0.555 0.444 0.000
S06.0 Concussion
0.555 0.444 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.555 0.445 0.000
S02.4 Fracture of malar and maxillary bones
0.554 0.446 0.000
O75.6 Delayed delivery after spontaneous or unspecified rupture of membranes
0.554 0.446 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.553 0.446 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.552 0.448 0.000
G96 Other disorders of central nervous system
0.552 0.448 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.552 0.448 0.000
G90 Disorders of autonomic nervous system
0.552 0.448 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.552 0.448 0.000
G92 Toxic encephalopathy
0.552 0.448 0.000
X60-X84 Intentional self-harm
0.551 0.449 0.000
S01.5 Open wound of lip and oral cavity
0.549 0.451 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.549 0.451 0.000
H05 Disorders of orbit
0.549 0.451 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.549 0.451 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.547 0.453 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.546 0.454 0.000
Y59 Other and unspecified vaccines and biological substances
0.545 0.455 0.000
Y58 Bacterial vaccines
0.545 0.455 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.545 0.455 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.545 0.455 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.545 0.455 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.545 0.455 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.545 0.455 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.545 0.455 0.000
Y48 Anaesthetics and therapeutic gases
0.545 0.455 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.545 0.455 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.545 0.455 0.000
Y44 Agents primarily affecting blood constituents
0.545 0.455 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.545 0.455 0.000
O30 Multiple gestation
0.545 0.455 0.000
Q60-Q64 Congenital malformations of the urinary system
0.544 0.456 0.000
T78.9 Adverse effect, unspecified
0.541 0.458 0.000
T78.8 Other adverse effects, not elsewhere classified
0.541 0.458 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.541 0.458 0.000
H00 Hordeolum and chalazion
0.539 0.461 0.000
S05.1 Contusion of eyeball and orbital tissues
0.539 0.461 0.000
S60 Superficial injury of wrist and hand
0.538 0.462 0.000
S62 Fracture at wrist and hand level
0.537 0.463 0.000
O46.9 Antepartum haemorrhage, unspecified
0.536 0.464 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.536 0.464 0.000
G83 Other paralytic syndromes
0.535 0.465 0.000
O63.1 Prolonged second stage (of labour)
0.535 0.465 0.000
S06.30 Focal brain injury (without open intracranial wound)
0.534 0.466 0.000
S69 Other and unspecified injuries of wrist and hand
0.534 0.466 0.000
S67 Crushing injury of wrist and hand
0.534 0.466 0.000
S65 Injury of blood vessels at wrist and hand level
0.534 0.466 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.534 0.466 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.532 0.468 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.532 0.468 0.000
S09.9 Unspecified injury of head
0.531 0.469 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.529 0.471 0.000
H11 Other disorders of conjunctiva
0.529 0.471 0.000
S91 Open wound of ankle and foot
0.528 0.472 0.000
S61.8 Open wound of other parts of wrist and hand
0.528 0.472 0.000
H02.5 Other disorders affecting eyelid function
0.528 0.472 0.000
Y42.5 Other oestrogens and progestogens
0.527 0.473 0.000
F03 Unspecified dementia
0.527 0.473 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.527 0.473 0.000
O41.8 Other specified disorders of amniotic fluid and membranes
0.527 0.473 0.000
S64 Injury of nerves at wrist and hand level
0.526 0.474 0.000
H26.3 Drug-induced cataract
0.525 0.474 0.000
H26.2 Complicated cataract
0.525 0.474 0.000
H26.1 Traumatic cataract
0.525 0.474 0.000
H26.0 Infantile, juvenile and presenile cataract
0.525 0.474 0.000
S42.9 Fracture of shoulder girdle, part unspecified
0.524 0.476 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.524 0.476 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.524 0.476 0.000
S42.4 Fracture of lower end of humerus
0.524 0.476 0.000
S42.3 Fracture of shaft of humerus
0.524 0.476 0.000
S42.1 Fracture of scapula
0.524 0.476 0.000
Y43.3 Other antineoplastic drugs
0.521 0.479 0.000
S01.0 Open wound of scalp
0.519 0.481 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.516 0.484 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.515 0.484 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.515 0.485 0.000
F70-F79 Mental retardation
0.515 0.485 0.000
F60-F69 Disorders of adult personality and behaviour
0.515 0.485 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.515 0.485 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.515 0.485 0.000
B02 Zoster [herpes zoster]
0.514 0.486 0.000
H36 Retinal disorders in diseases classified elsewhere
0.514 0.486 0.000
O75.9 Complication of labour and delivery, unspecified
0.511 0.488 0.000
O75.8 Other specified complications of labour and delivery
0.511 0.488 0.000
O75.7 Vaginal delivery following previous Caesarean section
0.511 0.488 0.000
O75.5 Delayed delivery after artificial rupture of membranes
0.511 0.488 0.000
O75.4 Other complications of obstetric surgery and procedures
0.511 0.488 0.000
O75.3 Other infection during labour
0.511 0.488 0.000
O75.1 Shock during or following labour and delivery
0.511 0.488 0.000
O75.0 Maternal distress during labour and delivery
0.511 0.488 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.511 0.489 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.509 0.490 0.000
Q80-Q89 Other congenital malformations
0.509 0.490 0.000
Q50-Q56 Congenital malformations of genital organs
0.509 0.490 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.509 0.490 0.000
Q35-Q37 Cleft lip and cleft palate
0.509 0.490 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.509 0.490 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.509 0.490 0.000
Q00-Q07 Congenital malformations of the nervous system
0.509 0.490 0.000
S43.7 Sprain and strain of other and unspecified parts of shoulder girdle
0.509 0.490 0.000
S43.6 Sprain and strain of sternoclavicular joint
0.509 0.490 0.000
S43.5 Sprain and strain of acromioclavicular joint
0.509 0.490 0.000
S43.4 Sprain and strain of shoulder joint
0.509 0.490 0.000
S43.3 Dislocation of other and unspecified parts of shoulder girdle
0.509 0.490 0.000
S43.2 Dislocation of sternoclavicular joint
0.509 0.490 0.000
S43.1 Dislocation of acromioclavicular joint
0.509 0.490 0.000
F99-F99 Unspecified mental disorder
0.509 0.491 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.509 0.491 0.000
B07 Viral warts
0.509 0.491 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.508 0.492 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.508 0.492 0.000
H55 Nystagmus and other irregular eye movements
0.508 0.492 0.000
S29 Other and unspecified injuries of thorax
0.508 0.492 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.508 0.492 0.000
S26 Injury of heart
0.508 0.492 0.000
S25 Injury of blood vessels of thorax
0.508 0.492 0.000
S24 Injury of nerves and spinal cord at thorax level
0.508 0.492 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.508 0.492 0.000
S21 Open wound of thorax
0.508 0.492 0.000
S20 Superficial injury of thorax
0.508 0.492 0.000
O64.9 Obstructed labour due to malposition and malpresentation, unspecified
0.508 0.492 0.000
O64.8 Obstructed labour due to other malposition and malpresentation
0.508 0.492 0.000
O64.5 Obstructed labour due to compound presentation
0.508 0.492 0.000
O64.4 Obstructed labour due to shoulder presentation
0.508 0.492 0.000
O64.3 Obstructed labour due to brow presentation
0.508 0.492 0.000
O64.2 Obstructed labour due to face presentation
0.508 0.492 0.000
O64.0 Obstructed labour due to incomplete rotation of foetal head
0.508 0.492 0.000
G80 Infantile cerebral palsy
0.506 0.494 0.000
T19 Foreign body in genito-urinary tract
0.505 0.495 0.000
T17 Foreign body in respiratory tract
0.505 0.495 0.000
T15 Foreign body on external eye
0.505 0.495 0.000
T16 Foreign body in ear
0.505 0.495 0.000
A30-A49 Other bacterial diseases
0.505 0.495 0.000
O48 Prolonged pregnancy
0.505 0.495 0.000
H48 Disorders of optic [2nd] nerve and visual pathways in diseases classified elsewhere
0.505 0.495 0.000
H46 Optic neuritis
0.505 0.495 0.000
H53-H54 Visual disturbances and blindness
0.504 0.496 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.503 0.497 0.000
T92 Sequelae of injuries of upper limb
0.503 0.497 0.000
S02.1 Fracture of base of skull
0.502 0.498 0.000
F00 Dementia in Alzheimer's disease
0.502 0.498 0.000
J09-J18 Influenza and pneumonia
0.501 0.499 0.000
S89 Other and unspecified injuries of lower leg
0.501 0.499 0.000
S02.2 Fracture of nasal bones
0.499 0.500 0.000
H25.9 Senile cataract, unspecified
0.499 0.501 0.000
V18.0 Driver injured in nontraffic accident
0.499 0.501 0.000
S06.20 Diffuse brain injury (without open intracranial wound)
0.498 0.502 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.497 0.503 0.000
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)
0.496 0.503 0.000
Y52.3 Coronary vasodilators, not elsewhere classified
0.496 0.504 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.495 0.505 0.000
O80-O84 Delivery
0.494 0.506 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.493 0.506 0.000
O97 Death from sequelae of direct obstetric causes
0.493 0.506 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.493 0.506 0.000
O95 Obstetric death of unspecified cause
0.493 0.506 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.493 0.506 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.493 0.507 0.000
S02.8 Fractures of other skull and facial bones
0.493 0.507 0.000
S02.7 Multiple fractures involving skull and facial bones
0.493 0.507 0.000
S02.5 Fracture of tooth
0.493 0.507 0.000
S02.3 Fracture of orbital floor
0.493 0.507 0.000
S02.0 Fracture of vault of skull
0.493 0.507 0.000
J00-J06 Acute upper respiratory infections
0.492 0.508 0.000
G91.8 Other hydrocephalus
0.491 0.509 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.491 0.509 0.000
G91.2 Normal-pressure hydrocephalus
0.491 0.509 0.000
G91.0 Communicating hydrocephalus
0.491 0.509 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.491 0.509 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.491 0.509 0.000
O36.8 Maternal care for other specified foetal problems
0.490 0.510 0.000
T18.1 Foreign body in oesophagus
0.489 0.511 0.000
W00-W19 Falls
0.489 0.511 0.000
H35.4 Peripheral retinal degeneration
0.489 0.511 0.000
O41.0 Oligohydramnios
0.489 0.511 0.000
S61.7 Multiple open wounds of wrist and hand
0.489 0.511 0.000
Y52.5 Other antihypertensive drugs, not elsewhere classified
0.489 0.511 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.489 0.511 0.000
H57.0 Anomalies of pupillary function
0.488 0.512 0.000
O63.2 Delayed delivery of second twin, triplet, etc.
0.487 0.512 0.000
S81 Open wound of lower leg
0.487 0.512 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.487 0.513 0.000
S40.8 Other superficial injuries of shoulder and upper arm
0.487 0.513 0.000
S40.7 Multiple superficial injuries of shoulder and upper arm
0.487 0.513 0.000
S40.0 Contusion of shoulder and upper arm
0.487 0.513 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.487 0.513 0.000
B18 Chronic viral hepatitis
0.486 0.514 0.000
H13 Disorders of conjunctiva in diseases classified elsewhere
0.486 0.514 0.000
H10 Conjunctivitis
0.486 0.514 0.000
S02.6 Fracture of mandible
0.485 0.515 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.485 0.515 0.000
S42.21 Fracture of upper end of humerus (open)
0.485 0.515 0.000
G72 Other myopathies
0.484 0.515 0.000
H25.2 Senile cataract, morgagnian type
0.484 0.516 0.000
S05.9 Injury of eye and orbit, part unspecified
0.484 0.516 0.000
S05.8 Other injuries of eye and orbit
0.484 0.516 0.000
S05.7 Avulsion of eye
0.484 0.516 0.000
S05.6 Penetrating wound of eyeball without foreign body
0.484 0.516 0.000
S05.5 Penetrating wound of eyeball with foreign body
0.484 0.516 0.000
S05.4 Penetrating wound of orbit with or without foreign body
0.484 0.516 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.484 0.516 0.000
S05.2 Ocular laceration and rupture with prolapse or loss of intraocular tissue
0.484 0.516 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.484 0.516 0.000
H25.1 Senile nuclear cataract
0.484 0.516 0.000
O36.5 Maternal care for poor foetal growth
0.483 0.516 0.000
G81 Hemiplegia
0.483 0.517 0.000
A04.8 Other specified bacterial intestinal infections
0.483 0.517 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.482 0.517 0.000
S68 Traumatic amputation of wrist and hand
0.482 0.518 0.000
H47.1 Papilloedema, unspecified
0.481 0.518 0.000
G37 Other demyelinating diseases of central nervous system
0.481 0.519 0.000
G36 Other acute disseminated demyelination
0.481 0.519 0.000
S09.8 Other specified injuries of head
0.481 0.519 0.000
S09.7 Multiple injuries of head
0.481 0.519 0.000
S09.2 Traumatic rupture of ear drum
0.481 0.519 0.000
S09.1 Injury of muscle and tendon of head
0.481 0.519 0.000
S09.0 Injury of blood vessels of head, not elsewhere classified
0.481 0.519 0.000
H02.4 Ptosis of eyelid
0.480 0.520 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.480 0.520 0.000
A07 Other protozoal intestinal diseases
0.479 0.521 0.000
A06 Amoebiasis
0.479 0.521 0.000
A05 Other bacterial foodborne intoxications
0.479 0.521 0.000
A03 Shigellosis
0.479 0.521 0.000
A02 Other Salmonella infections
0.479 0.521 0.000
A01 Typhoid and paratyphoid fevers
0.479 0.521 0.000
A00 Cholera
0.479 0.521 0.000
B37 Candidiasis
0.479 0.521 0.000
S99 Other and unspecified injuries of ankle and foot
0.478 0.522 0.000
S98 Traumatic amputation of ankle and foot
0.478 0.522 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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