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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12310380
log Bayes Factor = 8.99711
Chromosome 12   position 104,478,790  (GRCh37) Explore rs12310380 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
M45-M49 Spondylopathies
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
M47.9 Spondylosis, unspecified
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
M47 Spondylosis
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.998 0.002 0.000
I20-I25 Ischaemic heart diseases
0.997 0.003 0.000
I25 Chronic ischaemic heart disease
0.997 0.003 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.997 0.003 0.000
E78.0 Pure hypercholesterolaemia
0.994 0.006 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.994 0.006 0.000
E70-E90 Metabolic disorders
0.994 0.006 0.000
Chapter XX External causes of morbidity and mortality
0.990 0.010 0.000
M47.90 Spondylosis, unspecified (Multiple sites in spine)
0.984 0.016 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.980 0.020 0.000
G40-G47 Episodic and paroxysmal disorders
0.977 0.023 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.974 0.026 0.000
G90-G99 Other disorders of the nervous system
0.974 0.026 0.000
M45 Ankylosing spondylitis
0.971 0.029 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.965 0.035 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.964 0.036 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.947 0.053 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.946 0.054 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.943 0.057 0.000
L60-L75 Disorders of skin appendages
0.942 0.058 0.000
L72 Follicular cysts of skin and subcutaneous tissue
0.936 0.064 0.000
L72.1 Trichilemmal cyst
0.936 0.064 0.000
Q60-Q64 Congenital malformations of the urinary system
0.936 0.064 0.000
E50-E64 Other nutritional deficiencies
0.932 0.068 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.930 0.070 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.917 0.083 0.000
L50-L54 Urticaria and erythema
0.916 0.084 0.000
Q61 Cystic kidney disease
0.915 0.085 0.000
O42 Premature rupture of membranes
0.911 0.089 0.000
M05-M14 Inflammatory polyarthropathies
0.909 0.091 0.000
I10-I15 Hypertensive diseases
0.908 0.092 0.000
M80-M85 Disorders of bone density and structure
0.905 0.095 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.898 0.102 0.000
E00-E07 Disorders of thyroid gland
0.894 0.106 0.000
M13 Other arthritis
0.894 0.106 0.000
I22 Subsequent myocardial infarction
0.893 0.107 0.000
G44 Other headache syndromes
0.887 0.113 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.887 0.113 0.000
I12 Hypertensive renal disease
0.881 0.119 0.000
L53 Other erythematous conditions
0.879 0.121 0.000
G47 Sleep disorders
0.878 0.122 0.000
M13.9 Arthritis, unspecified
0.875 0.125 0.000
G30-G32 Other degenerative diseases of the nervous system
0.874 0.126 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.872 0.128 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.869 0.131 0.000
Chapter I Certain infectious and parasitic diseases
0.869 0.131 0.000
Y43 Primarily systemic agents
0.868 0.132 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.865 0.135 0.000
M86-M90 Other osteopathies
0.863 0.137 0.000
G91 Hydrocephalus
0.863 0.137 0.000
O42.9 Premature rupture of membranes, unspecified
0.861 0.139 0.000
I25.1 Atherosclerotic heart disease
0.861 0.139 0.000
I25.2 Old myocardial infarction
0.859 0.141 0.000
L53.9 Erythematous condition, unspecified
0.855 0.145 0.000
I12.0 Hypertensive renal disease with renal failure
0.854 0.146 0.000
G44.2 Tension-type headache
0.852 0.148 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.848 0.152 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.846 0.154 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.845 0.155 0.000
G95 Other diseases of spinal cord
0.842 0.158 0.000
G90 Disorders of autonomic nervous system
0.840 0.160 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.839 0.161 0.000
Q61.3 Polycystic kidney, unspecified
0.835 0.165 0.000
E10-E14 Diabetes mellitus
0.826 0.174 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.826 0.174 0.000
M84 Disorders of continuity of bone
0.823 0.177 0.000
E78.6 Lipoprotein deficiency
0.821 0.179 0.000
O60-O75 Complications of labour and delivery
0.821 0.179 0.000
O36 Maternal care for other known or suspected foetal problems
0.820 0.180 0.000
G06 Intracranial and intraspinal abscess and granuloma
0.820 0.180 0.000
Q61.0 Congenital single renal cyst
0.820 0.180 0.000
G99.2 Myelopathy in diseases classified elsewhere
0.820 0.180 0.000
I25.4 Coronary artery aneurysm
0.819 0.181 0.000
E78.8 Other disorders of lipoprotein metabolism
0.814 0.186 0.000
E04 Other non-toxic goitre
0.813 0.187 0.000
M45.X2 Ankylosing spondylitis (Cervical region)
0.812 0.188 0.000
E53 Deficiency of other B group vitamins
0.812 0.188 0.000
V80-V89 Other land transport accidents
0.810 0.190 0.000
M46 Other inflammatory spondylopathies
0.809 0.191 0.000
Chapter VIII Diseases of the ear and mastoid process
0.808 0.192 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.808 0.192 0.000
M91-M94 Chondropathies
0.807 0.193 0.000
M47.98 Spondylosis, unspecified (Sacral and sacrococcygeal region)
0.806 0.194 0.000
Q50-Q56 Congenital malformations of genital organs
0.805 0.195 0.000
O42.0 Premature rupture of membranes, onset of labour within 24 hours
0.803 0.197 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.800 0.200 0.000
Y43.3 Other antineoplastic drugs
0.797 0.203 0.000
Y44 Agents primarily affecting blood constituents
0.796 0.204 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.795 0.205 0.000
E85 Amyloidosis
0.793 0.207 0.000
G91.9 Hydrocephalus, unspecified
0.793 0.207 0.000
O48 Prolonged pregnancy
0.793 0.207 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.792 0.208 0.000
M81 Osteoporosis without pathological fracture
0.792 0.208 0.000
M45.X0 Ankylosing spondylitis (Multiple sites in spine)
0.792 0.208 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.792 0.208 0.000
I70 Atherosclerosis
0.788 0.212 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.787 0.213 0.000
M47.1 Other spondylosis with myelopathy
0.785 0.215 0.000
H60-H62 Diseases of external ear
0.784 0.216 0.000
W00-W19 Falls
0.784 0.216 0.000
G08 Intracranial and intraspinal phlebitis and thrombophlebitis
0.783 0.217 0.000
O36.9 Maternal care for foetal problem, unspecified
0.782 0.218 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.782 0.218 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.782 0.218 0.000
G96 Other disorders of central nervous system
0.782 0.218 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.781 0.219 0.000
E61 Deficiency of other nutrient elements
0.779 0.221 0.000
I11 Hypertensive heart disease
0.776 0.224 0.000
M00-M03 Infectious arthropathies
0.775 0.224 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.772 0.228 0.000
D60-D64 Aplastic and other anaemias
0.768 0.232 0.000
H61 Other disorders of external ear
0.767 0.233 0.000
G04 Encephalitis, myelitis and encephalomyelitis
0.761 0.239 0.000
Q61.2 Polycystic kidney, adult type
0.761 0.239 0.000
X10-X19 Contact with heat and hot substances
0.760 0.239 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.760 0.240 0.000
S00-S09 Injuries to the head
0.759 0.241 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.759 0.241 0.000
B35-B49 Mycoses
0.758 0.242 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.758 0.242 0.000
W50-W64 Exposure to animate mechanical forces
0.758 0.242 0.000
Q00-Q07 Congenital malformations of the nervous system
0.757 0.243 0.000
E78.2 Mixed hyperlipidaemia
0.755 0.245 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.754 0.246 0.000
E55 Vitamin D deficiency
0.753 0.247 0.000
O85-O92 Complications predominantly related to the puerperium
0.752 0.248 0.000
O43 Placental disorders
0.751 0.248 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.751 0.249 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.751 0.249 0.000
G47.8 Other sleep disorders
0.749 0.251 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.749 0.251 0.000
G20-G26 Extrapyramidal and movement disorders
0.748 0.252 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.745 0.255 0.000
E04.9 Non-toxic goitre, unspecified
0.743 0.257 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.743 0.257 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.740 0.260 0.000
I25.5 Ischaemic cardiomyopathy
0.740 0.260 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.739 0.261 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.739 0.261 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.739 0.261 0.000
V20-V29 Motorcycle rider injured in transport accident
0.738 0.262 0.000
G06.1 Intraspinal abscess and granuloma
0.738 0.262 0.000
I71 Aortic aneurysm and dissection
0.737 0.263 0.000
I73 Other peripheral vascular diseases
0.737 0.263 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.736 0.264 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.734 0.266 0.000
G41 Status epilepticus
0.734 0.266 0.000
O40 Polyhydramnios
0.734 0.266 0.000
G95.1 Vascular myelopathies
0.733 0.267 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.733 0.267 0.000
O41 Other disorders of amniotic fluid and membranes
0.732 0.268 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.732 0.268 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.732 0.268 0.000
Y86 Sequelae of other accidents
0.731 0.269 0.000
I20 Angina pectoris
0.729 0.271 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.728 0.272 0.000
M13.93 Arthritis, unspecified (Forearm)
0.726 0.274 0.000
O61 Failed induction of labour
0.725 0.275 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.725 0.275 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.724 0.276 0.000
S00 Superficial injury of head
0.723 0.277 0.000
B15-B19 Viral hepatitis
0.722 0.278 0.000
E74 Other disorders of carbohydrate metabolism
0.722 0.278 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.722 0.278 0.000
G02 Meningitis in other infectious and parasitic diseases classified elsewhere
0.720 0.280 0.000
I70.2 Atherosclerosis of arteries of the extremities
0.720 0.280 0.000
G70-G73 Diseases of myoneural junction and muscle
0.719 0.281 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.719 0.281 0.000
E86 Volume depletion
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.717 0.283 0.000
M47.95 Spondylosis, unspecified (Thoracolumbar region)
0.717 0.283 0.000
M47.94 Spondylosis, unspecified (Thoracic region)
0.717 0.283 0.000
M47.93 Spondylosis, unspecified (Cervicothoracic region)
0.717 0.283 0.000
M47.91 Spondylosis, unspecified (Occipito-atlanto-axial region)
0.717 0.283 0.000
D55-D59 Haemolytic anaemias
0.717 0.283 0.000
M47.0 Anterior spinal and vertebral artery compression syndromes
0.716 0.283 0.000
X60-X84 Intentional self-harm
0.716 0.283 0.000
M88 Paget's disease of bone [osteitis deformans]
0.716 0.284 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
I25.6 Silent myocardial ischaemia
0.715 0.285 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.715 0.285 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.715 0.285 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.715 0.285 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.714 0.286 0.000
M81.9 Osteoporosis, unspecified
0.714 0.286 0.000
G63 Polyneuropathy in diseases classified elsewhere
0.713 0.287 0.000
E78.3 Hyperchylomicronaemia
0.713 0.287 0.000
E78.1 Pure hyperglyceridaemia
0.713 0.287 0.000
Y48 Anaesthetics and therapeutic gases
0.712 0.287 0.000
E84 Cystic fibrosis
0.712 0.287 0.000
E79 Disorders of purine and pyrimidine metabolism
0.712 0.287 0.000
E77 Disorders of glycoprotein metabolism
0.712 0.287 0.000
E76 Disorders of glycosaminoglycan metabolism
0.712 0.287 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.712 0.287 0.000
E72 Other disorders of amino-acid metabolism
0.712 0.287 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.712 0.287 0.000
E70 Disorders of aromatic amino-acid metabolism
0.712 0.287 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.712 0.287 0.000
L65 Other nonscarring hair loss
0.711 0.289 0.000
I22.8 Subsequent myocardial infarction of other sites
0.711 0.289 0.000
E14 Unspecified diabetes mellitus
0.710 0.290 0.000
Y35-Y36 Legal intervention and operations of war
0.710 0.290 0.000
Y10-Y34 Event of undetermined intent
0.710 0.290 0.000
X85-X99 Assault
0.710 0.290 0.000
X30-X39 Exposure to forces of nature
0.710 0.290 0.000
X00-X09 Exposure to smoke, fire and flames
0.710 0.290 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.710 0.290 0.000
W75-W84 Other accidental threats to breathing
0.710 0.290 0.000
W65-W74 Accidental drowning and submersion
0.710 0.290 0.000
V98-V99 Other and unspecified transport accidents
0.710 0.290 0.000
V95-V97 Air and space transport accidents
0.710 0.290 0.000
V90-V94 Water transport accidents
0.710 0.290 0.000
V70-V79 Bus occupant injured in transport accident
0.710 0.290 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.710 0.290 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.710 0.290 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.710 0.290 0.000
S09 Other and unspecified injuries of head
0.709 0.291 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.709 0.291 0.000
A30-A49 Other bacterial diseases
0.708 0.292 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.708 0.292 0.000
E13 Other specified diabetes mellitus
0.708 0.292 0.000
G95.8 Other specified diseases of spinal cord
0.707 0.292 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.707 0.293 0.000
M87 Osteonecrosis
0.707 0.293 0.000
Y40 Systemic antibiotics
0.706 0.294 0.000
O00-O08 Pregnancy with abortive outcome
0.706 0.294 0.000
M49 Spondylopathies in diseases classified elsewhere
0.706 0.294 0.000
E53.8 Deficiency of other specified B group vitamins
0.706 0.294 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
M13.0 Polyarthritis, unspecified
0.705 0.295 0.000
M13.8 Other specified arthritis
0.703 0.297 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
Y54.5 Other diuretics
0.702 0.298 0.000
Y54.4 Loop [high-ceiling] diuretics
0.702 0.298 0.000
M86 Osteomyelitis
0.701 0.299 0.000
Y43.1 Antineoplastic antimetabolites
0.701 0.299 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.701 0.299 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.701 0.299 0.000
I12.9 Hypertensive renal disease without renal failure
0.701 0.299 0.000
B37 Candidiasis
0.700 0.300 0.000
E06 Thyroiditis
0.700 0.300 0.000
O46.9 Antepartum haemorrhage, unspecified
0.699 0.301 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.699 0.301 0.000
Q35-Q37 Cleft lip and cleft palate
0.699 0.301 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.699 0.301 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.698 0.302 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.698 0.302 0.000
G92 Toxic encephalopathy
0.698 0.302 0.000
E88 Other metabolic disorders
0.698 0.302 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.697 0.303 0.000
M45.X8 Ankylosing spondylitis (Sacral and sacrococcygeal region)
0.696 0.304 0.000
M45.X7 Ankylosing spondylitis (Lumbosacral region)
0.696 0.304 0.000
M45.X6 Ankylosing spondylitis (Lumbar region)
0.696 0.304 0.000
M45.X5 Ankylosing spondylitis (Thoracolumbar region)
0.696 0.304 0.000
M45.X4 Ankylosing spondylitis (Thoracic region)
0.696 0.304 0.000
M45.X3 Ankylosing spondylitis (Cervicothoracic region)
0.696 0.304 0.000
M45.X1 Ankylosing spondylitis (Occipito-atlanto-axial region)
0.696 0.304 0.000
I26 Pulmonary embolism
0.694 0.305 0.000
Y00-Y09 Assault
0.694 0.306 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.693 0.307 0.000
L10-L14 Bullous disorders
0.692 0.308 0.000
G12 Spinal muscular atrophy and related syndromes
0.692 0.308 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.691 0.309 0.000
G47.4 Narcolepsy and cataplexy
0.690 0.310 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.310 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.690 0.310 0.000
I73.0 Raynaud's syndrome
0.689 0.311 0.000
H61.8 Other specified disorders of external ear
0.689 0.311 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.689 0.311 0.000
M14 Arthropathies in other diseases classified elsewhere
0.687 0.313 0.000
Q50 Congenital malformations of ovaries, Fallopian tubes and broad ligaments
0.686 0.314 0.000
Q61.5 Medullary cystic kidney
0.684 0.315 0.000
M10 Gout
0.683 0.317 0.000
O70 Perineal laceration during delivery
0.683 0.317 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.683 0.317 0.000
I05-I09 Chronic rheumatic heart diseases
0.679 0.321 0.000
G03 Meningitis due to other and unspecified causes
0.679 0.321 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.679 0.321 0.000
Y59 Other and unspecified vaccines and biological substances
0.679 0.321 0.000
Y58 Bacterial vaccines
0.679 0.321 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.679 0.321 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.679 0.321 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.679 0.321 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.679 0.321 0.000
O62 Abnormalities of forces of labour
0.679 0.321 0.000
M84.15 Nonunion of fracture [pseudarthrosis] (Pelvic region and thigh)
0.678 0.322 0.000
Q80-Q89 Other congenital malformations
0.678 0.322 0.000
G01 Meningitis in bacterial diseases classified elsewhere
0.677 0.322 0.000
M46.4 Discitis, unspecified
0.677 0.323 0.000
H61.0 Perichondritis of external ear
0.676 0.324 0.000
V89 Motor- or nonmotor-vehicle accident, type of vehicle unspecified
0.676 0.324 0.000
G05 Encephalitis, myelitis and encephalomyelitis in diseases classified elsewhere
0.676 0.324 0.000
G00 Bacterial meningitis, not elsewhere classified
0.676 0.324 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.676 0.324 0.000
G07 Intracranial and intraspinal abscess and granuloma in diseases classified elsewhere
0.676 0.324 0.000
L75 Apocrine sweat disorders
0.675 0.324 0.000
L74 Eccrine sweat disorders
0.675 0.324 0.000
L70 Acne
0.675 0.324 0.000
L68 Hypertrichosis
0.675 0.324 0.000
L67 Hair colour and hair shaft abnormalities
0.675 0.324 0.000
L66 Cicatricial alopecia [scarring hair loss]
0.675 0.324 0.000
L64 Androgenic alopecia
0.675 0.324 0.000
L63 Alopecia areata
0.675 0.324 0.000
L62 Nail disorders in diseases classified elsewhere
0.675 0.324 0.000
L72.8 Other follicular cysts of skin and subcutaneous tissue
0.675 0.325 0.000
E78.4 Other hyperlipidaemia
0.675 0.325 0.000
L50 Urticaria
0.674 0.326 0.000
A49 Bacterial infection of unspecified site
0.672 0.328 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.671 0.328 0.000
L72.2 Steatocystoma multiplex
0.671 0.329 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.671 0.329 0.000
Q64 Other congenital malformations of urinary system
0.671 0.329 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.671 0.329 0.000
I70.20 Atherosclerosis of arteries of extremities (without gangrene)
0.671 0.329 0.000
E61.1 Iron deficiency
0.670 0.330 0.000
Y85 Sequelae of transport accidents
0.669 0.330 0.000
D63.0 Anaemia in neoplastic disease
0.669 0.331 0.000
S09.9 Unspecified injury of head
0.669 0.331 0.000
E78.5 Hyperlipidaemia, unspecified
0.668 0.332 0.000
E64 Sequelae of malnutrition and other nutritional deficiencies
0.668 0.332 0.000
E63 Other nutritional deficiencies
0.668 0.332 0.000
E56 Other vitamin deficiencies
0.668 0.332 0.000
E51 Thiamine deficiency
0.668 0.332 0.000
E50 Vitamin A deficiency
0.668 0.332 0.000
E60 Dietary zinc deficiency
0.668 0.332 0.000
E59 Dietary selenium deficiency
0.668 0.332 0.000
E58 Dietary calcium deficiency
0.668 0.332 0.000
E54 Ascorbic acid deficiency
0.668 0.332 0.000
E52 Niacin deficiency [pellagra]
0.668 0.332 0.000
L73 Other follicular disorders
0.668 0.332 0.000
G90.3 Multisystem degeneration
0.667 0.333 0.000
O03 Spontaneous abortion
0.667 0.333 0.000
O33 Maternal care for known or suspected disproportion
0.667 0.333 0.000
O31 Complications specific to multiple gestation
0.667 0.333 0.000
E73 Lactose intolerance
0.665 0.335 0.000
M82 Osteoporosis in diseases classified elsewhere
0.664 0.336 0.000
G63.2 Diabetic polyneuropathy
0.664 0.336 0.000
O36.4 Maternal care for intra-uterine death
0.664 0.336 0.000
E04.1 Non-toxic single thyroid nodule
0.663 0.337 0.000
W06 Fall involving bed
0.662 0.338 0.000
I11.9 Hypertensive heart disease without (congestive) heart failure
0.662 0.338 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.662 0.338 0.000
B50-B64 Protozoal diseases
0.659 0.340 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.659 0.341 0.000
O45 Premature separation of placenta [abruptio placentae]
0.659 0.341 0.000
B37.0 Candidal stomatitis
0.659 0.341 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.658 0.341 0.000
D72 Other disorders of white blood cells
0.658 0.342 0.000
M84.17 Nonunion of fracture [pseudarthrosis] (Ankle and foot)
0.658 0.342 0.000
O61.0 Failed medical induction of labour
0.657 0.343 0.000
L54 Erythema in diseases classified elsewhere
0.657 0.343 0.000
L51 Erythema multiforme
0.657 0.343 0.000
M13.98 Arthritis, unspecified (Other)
0.656 0.344 0.000
M94 Other disorders of cartilage
0.656 0.344 0.000
Q61.9 Cystic kidney disease, unspecified
0.656 0.344 0.000
Q61.8 Other cystic kidney diseases
0.656 0.344 0.000
Q61.4 Renal dysplasia
0.656 0.344 0.000
Q61.1 Polycystic kidney, infantile type
0.656 0.344 0.000
W08 Fall involving other furniture
0.655 0.345 0.000
H61.9 Disorder of external ear, unspecified
0.655 0.345 0.000
X20-X29 Contact with venomous animals and plants
0.655 0.345 0.000
B07 Viral warts
0.655 0.345 0.000
S00.3 Superficial injury of nose
0.655 0.345 0.000
G11 Hereditary ataxia
0.654 0.346 0.000
I60-I69 Cerebrovascular diseases
0.654 0.346 0.000
O42.2 Premature rupture of membranes, labour delayed by therapy
0.653 0.347 0.000
L52 Erythema nodosum
0.653 0.347 0.000
W20-W49 Exposure to inanimate mechanical forces
0.653 0.347 0.000
A15-A19 Tuberculosis
0.652 0.347 0.000
S10-S19 Injuries to the neck
0.652 0.348 0.000
G90.0 Idiopathic peripheral autonomic neuropathy
0.652 0.348 0.000
M12 Other specific arthropathies
0.652 0.348 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.652 0.348 0.000
M08 Juvenile arthritis
0.652 0.348 0.000
I13 Hypertensive heart and renal disease
0.651 0.349 0.000
M11 Other crystal arthropathies
0.650 0.350 0.000
E85.4 Organ-limited amyloidosis
0.649 0.351 0.000
L03 Cellulitis
0.649 0.351 0.000
M83 Adult osteomalacia
0.649 0.351 0.000
G90.2 Horner's syndrome
0.648 0.351 0.000
Y44.2 Anticoagulants
0.648 0.352 0.000
B25-B34 Other viral diseases
0.648 0.352 0.000
Y54.3 Benzothiadiazine derivatives
0.648 0.352 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.647 0.353 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.647 0.353 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.647 0.353 0.000
O70.1 Second degree perineal laceration during delivery
0.645 0.355 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.644 0.356 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.644 0.356 0.000
G99.8 Other specified disorders of nervous system in diseases classified elsewhere
0.643 0.356 0.000
G99.1 Other disorders of autonomic nervous system in other diseases classified elsewhere
0.643 0.356 0.000
G31.2 Degeneration of nervous system due to alcohol
0.644 0.356 0.000
M81.98 Osteoporosis, unspecified (Other)
0.642 0.358 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.641 0.359 0.000
E00 Congenital iodine-deficiency syndrome
0.641 0.359 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.641 0.359 0.000
M13.1 Monoarthritis, not elsewhere classified
0.641 0.359 0.000
G25 Other extrapyramidal and movement disorders
0.640 0.360 0.000
B65-B83 Helminthiases
0.640 0.360 0.000
G47.9 Sleep disorder, unspecified
0.637 0.363 0.000
M84.0 Malunion of fracture
0.637 0.363 0.000
S00.9 Superficial injury of head, part unspecified
0.637 0.363 0.000
G44.3 Chronic posttraumatic headache
0.636 0.364 0.000
G44.1 Vascular headache, not elsewhere classified
0.636 0.364 0.000
T92 Sequelae of injuries of upper limb
0.636 0.364 0.000
E07 Other disorders of thyroid
0.635 0.365 0.000
G90.9 Disorder of autonomic nervous system, unspecified
0.635 0.365 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.634 0.366 0.000
E05.9 Thyrotoxicosis, unspecified
0.633 0.367 0.000
E14.9 Without complications
0.632 0.368 0.000
G95.9 Disease of spinal cord, unspecified
0.631 0.369 0.000
M47.12 Other spondylosis with myelopathy (Cervical region)
0.631 0.369 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.631 0.369 0.000
Y43.4 Immunosuppressive agents
0.631 0.369 0.000
Y44.5 Thrombolytic drugs
0.631 0.369 0.000
G43 Migraine
0.631 0.369 0.000
L53.3 Other chronic figurate erythema
0.630 0.370 0.000
L53.2 Erythema marginatum
0.630 0.370 0.000
L53.1 Erythema annulare centrifugum
0.630 0.370 0.000
L53.0 Toxic erythema
0.630 0.370 0.000
M85 Other disorders of bone density and structure
0.630 0.370 0.000
G47.2 Disorders of the sleep-wake schedule
0.629 0.371 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.629 0.371 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.627 0.372 0.000
I24 Other acute ischaemic heart diseases
0.627 0.373 0.000
G96.0 Cerebrospinal fluid leak
0.627 0.373 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.626 0.373 0.000
O03.4 Incomplete, without complication
0.626 0.374 0.000
O36.6 Maternal care for excessive foetal growth
0.626 0.374 0.000
I70.0 Atherosclerosis of aorta
0.626 0.374 0.000
M99 Biomechanical lesions, not elsewhere classified
0.625 0.374 0.000
E53.9 Vitamin B deficiency, unspecified
0.625 0.375 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.625 0.375 0.000
E55.9 Vitamin D deficiency, unspecified
0.624 0.376 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.623 0.377 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.623 0.377 0.000
A75-A79 Rickettsioses
0.623 0.377 0.000
A70-A74 Other diseases caused by chlamydiae
0.623 0.377 0.000
A65-A69 Other spirochaetal diseases
0.623 0.377 0.000
A20-A28 Certain zoonotic bacterial diseases
0.623 0.377 0.000
E13.9 Without complications
0.623 0.377 0.000
T17 Foreign body in respiratory tract
0.622 0.378 0.000
Y43.9 Primarily systemic agent, unspecified
0.622 0.378 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.622 0.378 0.000
Y43.6 Enzymes, not elsewhere classified
0.622 0.378 0.000
Y43.5 Acidifying and alkalising agents
0.622 0.378 0.000
Y43.2 Antineoplastic natural products
0.622 0.378 0.000
M93 Other osteochondropathies
0.621 0.379 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.620 0.380 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.620 0.380 0.000
G45.0 Vertebro-basilar artery syndrome
0.620 0.380 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.619 0.380 0.000
Y89 Sequelae of other external causes
0.619 0.381 0.000
G91.8 Other hydrocephalus
0.619 0.381 0.000
G91.3 Posttraumatic hydrocephalus, unspecified
0.619 0.381 0.000
G91.2 Normal-pressure hydrocephalus
0.619 0.381 0.000
G91.0 Communicating hydrocephalus
0.619 0.381 0.000
H61.3 Acquired stenosis of external ear canal
0.616 0.384 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.616 0.384 0.000
O21 Excessive vomiting in pregnancy
0.615 0.385 0.000
I69 Sequelae of cerebrovascular disease
0.615 0.385 0.000
M48 Other spondylopathies
0.615 0.385 0.000
M00 Pyogenic arthritis
0.615 0.385 0.000
W07 Fall involving chair
0.615 0.385 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.615 0.385 0.000
I20.8 Other forms of angina pectoris
0.614 0.386 0.000
D63.8 Anaemia in other chronic diseases classified elsewhere
0.614 0.386 0.000
B37.9 Candidiasis, unspecified
0.613 0.387 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.612 0.387 0.000
X50-X57 Overexertion, travel and privation
0.612 0.388 0.000
T00-T07 Injuries involving multiple body regions
0.612 0.388 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.612 0.388 0.000
D75 Other diseases of blood and blood-forming organs
0.612 0.388 0.000
M88.9 Paget's disease of bone, unspecified
0.611 0.389 0.000
G04.9 Encephalitis, myelitis and encephalomyelitis, unspecified
0.611 0.389 0.000
Y84.1 Kidney dialysis
0.610 0.389 0.000
M81.90 Osteoporosis, unspecified (Multiple sites)
0.610 0.390 0.000
Y46.6 Other and unspecified antiepileptics
0.610 0.390 0.000
O43.1 Malformation of placenta
0.609 0.391 0.000
Q65 Congenital deformities of hip
0.609 0.391 0.000
B08.1 Molluscum contagiosum
0.609 0.391 0.000
G83 Other paralytic syndromes
0.609 0.391 0.000
W17 Other fall from one level to another
0.608 0.391 0.000
Q04 Other congenital malformations of brain
0.608 0.392 0.000
G95.0 Syringomyelia and syringobulbia
0.607 0.393 0.000
Y51.6 @-Adrenoreceptor antagonists, not elsewhere classified
0.607 0.393 0.000
Q53 Undescended testicle
0.607 0.393 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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