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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12437393
log Bayes Factor = 11.2266
Chromosome 14   position 21,635,714  (GRCh37) Explore rs12437393 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.997 0.003 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.996 0.004 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.993 0.007 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.993 0.007 0.000
Chapter X Diseases of the respiratory system
0.992 0.008 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.991 0.009 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.986 0.014 0.000
S00-S09 Injuries to the head
0.970 0.030 0.000
Chapter XX External causes of morbidity and mortality
0.969 0.031 0.000
C79 Secondary malignant neoplasm of other sites
0.969 0.031 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.966 0.034 0.000
D80-D89 Certain disorders involving the immune mechanism
0.964 0.036 0.000
F10.2 Dependence syndrome
0.964 0.036 0.000
F30-F39 Mood [affective] disorders
0.960 0.040 0.000
C91 Lymphoid leukaemia
0.959 0.041 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.958 0.042 0.000
C64-C68 Malignant neoplasms of urinary tract
0.953 0.047 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.950 0.050 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
J20-J22 Other acute lower respiratory infections
0.944 0.056 0.000
F32 Depressive episode
0.943 0.057 0.000
J40-J47 Chronic lower respiratory diseases
0.940 0.060 0.000
T79-T79 Certain early complications of trauma
0.939 0.061 0.000
T66-T78 Other and unspecified effects of external causes
0.938 0.062 0.000
F41 Other anxiety disorders
0.936 0.064 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.934 0.066 0.000
F41.9 Anxiety disorder, unspecified
0.932 0.068 0.000
M70-M79 Other soft tissue disorders
0.931 0.069 0.000
C91.1 Chronic lymphocytic leukaemia
0.928 0.072 0.000
Q60-Q64 Congenital malformations of the urinary system
0.926 0.074 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.924 0.076 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.923 0.077 0.000
M50-M54 Other dorsopathies
0.917 0.083 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.916 0.084 0.000
D86 Sarcoidosis
0.915 0.085 0.000
C80 Malignant neoplasm without specification of site
0.914 0.086 0.000
J44 Other chronic obstructive pulmonary disease
0.912 0.088 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.904 0.096 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.902 0.098 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.900 0.100 0.000
S02 Fracture of skull and facial bones
0.899 0.101 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.895 0.105 0.000
T78 Adverse effects, not elsewhere classified
0.894 0.106 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.894 0.106 0.000
C71 Malignant neoplasm of brain
0.893 0.107 0.000
M79.0 Rheumatism, unspecified
0.890 0.110 0.000
M06 Other rheumatoid arthritis
0.888 0.112 0.000
Q50-Q56 Congenital malformations of genital organs
0.885 0.115 0.000
F10.1 Harmful use
0.885 0.115 0.000
T43.2 Other and unspecified antidepressants
0.880 0.120 0.000
J22 Unspecified acute lower respiratory infection
0.878 0.122 0.000
M10 Gout
0.874 0.126 0.000
D50-D53 Nutritional anaemias
0.873 0.127 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.871 0.129 0.000
Chapter VI Diseases of the nervous system
0.870 0.130 0.000
F32.9 Depressive episode, unspecified
0.868 0.132 0.000
F32.1 Moderate depressive episode
0.867 0.133 0.000
M79.09 Rheumatism, unspecified (Site unspecified)
0.867 0.133 0.000
J44.8 Other specified chronic obstructive pulmonary disease
0.865 0.135 0.000
D60-D64 Aplastic and other anaemias
0.865 0.135 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.858 0.142 0.000
J42 Unspecified chronic bronchitis
0.856 0.144 0.000
M50 Cervical disk disorders
0.855 0.145 0.000
F10.0 Acute intoxication
0.853 0.147 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.853 0.147 0.000
S02.2 Fracture of nasal bones
0.852 0.148 0.000
S00 Superficial injury of head
0.850 0.150 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.849 0.151 0.000
J60-J70 Lung diseases due to external agents
0.849 0.151 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.846 0.154 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.846 0.154 0.000
C78.7 Secondary malignant neoplasm of liver
0.844 0.156 0.000
M50.2 Other cervical disk displacement
0.842 0.158 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.842 0.158 0.000
D55-D59 Haemolytic anaemias
0.841 0.159 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.841 0.159 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.838 0.162 0.000
C88 Malignant immunoproliferative diseases
0.834 0.166 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.833 0.167 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.831 0.168 0.000
V10-V19 Pedal cyclist injured in transport accident
0.831 0.169 0.000
T78.4 Allergy, unspecified
0.827 0.173 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.827 0.173 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.825 0.174 0.000
F45 Somatoform disorders
0.825 0.175 0.000
D86.9 Sarcoidosis, unspecified
0.825 0.175 0.000
M06.9 Rheumatoid arthritis, unspecified
0.824 0.176 0.000
M10.9 Gout, unspecified
0.824 0.176 0.000
Q00-Q07 Congenital malformations of the nervous system
0.822 0.178 0.000
D84 Other immunodeficiencies
0.822 0.178 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.822 0.178 0.000
S02.20 Fracture of nasal bones (closed)
0.819 0.181 0.000
C80.9 Malignant neoplasm, unspecified
0.818 0.182 0.000
M86-M90 Other osteopathies
0.818 0.182 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.814 0.186 0.000
J84 Other interstitial pulmonary diseases
0.813 0.187 0.000
W00-W19 Falls
0.813 0.187 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.813 0.187 0.000
M40-M43 Deforming dorsopathies
0.811 0.189 0.000
T79.7 Traumatic subcutaneous emphysema
0.810 0.190 0.000
Q61 Cystic kidney disease
0.809 0.191 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.808 0.192 0.000
D62 Acute posthaemorrhagic anaemia
0.806 0.194 0.000
G90-G99 Other disorders of the nervous system
0.803 0.197 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.801 0.199 0.000
V40-V49 Car occupant injured in transport accident
0.801 0.199 0.000
F32.0 Mild depressive episode
0.799 0.201 0.000
M80-M85 Disorders of bone density and structure
0.798 0.202 0.000
M10.99 Gout, unspecified (Site unspecified)
0.798 0.202 0.000
S01 Open wound of head
0.798 0.202 0.000
G20-G26 Extrapyramidal and movement disorders
0.795 0.205 0.000
J80 Adult respiratory distress syndrome
0.794 0.206 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.792 0.208 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.792 0.208 0.000
M60-M63 Disorders of muscles
0.791 0.209 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.789 0.211 0.000
T00-T07 Injuries involving multiple body regions
0.789 0.211 0.000
S00.1 Contusion of eyelid and periocular area
0.787 0.213 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.786 0.214 0.000
C71.9 Brain, unspecified
0.786 0.214 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.783 0.217 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.778 0.222 0.000
J20 Acute bronchitis
0.777 0.223 0.000
F10.6 Amnesic syndrome
0.777 0.223 0.000
C95 Leukaemia of unspecified cell type
0.775 0.224 0.000
Q51 Congenital malformations of uterus and cervix
0.775 0.225 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.774 0.226 0.000
Chapter XI Diseases of the digestive system
0.774 0.226 0.000
O00-O08 Pregnancy with abortive outcome
0.774 0.226 0.000
C81 Hodgkin's disease
0.772 0.228 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.771 0.229 0.000
S05 Injury of eye and orbit
0.768 0.232 0.000
C85.1 B-cell lymphoma, unspecified
0.768 0.232 0.000
D52 Folate deficiency anaemia
0.768 0.232 0.000
M54 Dorsalgia
0.767 0.233 0.000
C71.1 Frontal lobe
0.767 0.233 0.000
C67 Malignant neoplasm of bladder
0.767 0.233 0.000
G25 Other extrapyramidal and movement disorders
0.765 0.235 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.765 0.235 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.763 0.237 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.760 0.240 0.000
Chapter VII Diseases of the eye and adnexa
0.757 0.243 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.757 0.243 0.000
D89 Other disorders involving the immune mechanism, not elsewhere classified
0.757 0.243 0.000
T79.6 Traumatic ischaemia of muscle
0.756 0.244 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.756 0.244 0.000
D86.0 Sarcoidosis of lung
0.756 0.244 0.000
T79.8 Other early complications of trauma
0.756 0.244 0.000
V01-V09 Pedestrian injured in transport accident
0.755 0.245 0.000
M76 Enthesopathies of lower limb, excluding foot
0.755 0.245 0.000
M65-M68 Disorders of synovium and tendon
0.755 0.245 0.000
F30 Manic episode
0.755 0.245 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.754 0.246 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.752 0.248 0.000
M79.00 Rheumatism, unspecified (Multiple sites)
0.752 0.248 0.000
X20-X29 Contact with venomous animals and plants
0.751 0.249 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.751 0.249 0.000
C91.9 Lymphoid leukaemia, unspecified
0.750 0.250 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.749 0.251 0.000
J40 Bronchitis, not specified as acute or chronic
0.749 0.251 0.000
D86.8 Sarcoidosis of other and combined sites
0.748 0.252 0.000
J09-J18 Influenza and pneumonia
0.746 0.254 0.000
S90-S99 Injuries to the ankle and foot
0.746 0.254 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.746 0.254 0.000
F03 Unspecified dementia
0.745 0.255 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.745 0.255 0.000
C65 Malignant neoplasm of renal pelvis
0.745 0.255 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.742 0.257 0.000
K90-K93 Other diseases of the digestive system
0.742 0.258 0.000
C78.0 Secondary malignant neoplasm of lung
0.742 0.258 0.000
C83.1 Small cleaved cell (diffuse)
0.741 0.259 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.740 0.260 0.000
K90 Intestinal malabsorption
0.740 0.260 0.000
M06.0 Seronegative rheumatoid arthritis
0.739 0.261 0.000
T21 Burn and corrosion of trunk
0.738 0.262 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.738 0.262 0.000
C71.3 Parietal lobe
0.738 0.262 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.737 0.263 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.737 0.263 0.000
W50-W64 Exposure to animate mechanical forces
0.736 0.264 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.736 0.264 0.000
S01.5 Open wound of lip and oral cavity
0.736 0.264 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.736 0.264 0.000
F10.3 Withdrawal state
0.735 0.265 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.735 0.265 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.734 0.265 0.000
Q43 Other congenital malformations of intestine
0.734 0.266 0.000
Q54 Hypospadias
0.733 0.267 0.000
K90.0 Coeliac disease
0.733 0.267 0.000
Q60.0 Renal agenesis, unilateral
0.733 0.267 0.000
F52 Sexual dysfunction, not caused by organic disorder or disease
0.733 0.267 0.000
T78.3 Angioneurotic oedema
0.733 0.267 0.000
D59 Acquired haemolytic anaemia
0.732 0.268 0.000
M54.3 Sciatica
0.727 0.273 0.000
T78.8 Other adverse effects, not elsewhere classified
0.726 0.274 0.000
J43 Emphysema
0.724 0.275 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.724 0.276 0.000
M43 Other deforming dorsopathies
0.724 0.276 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.723 0.277 0.000
K70-K77 Diseases of liver
0.723 0.277 0.000
Y44 Agents primarily affecting blood constituents
0.722 0.278 0.000
G93 Other disorders of brain
0.722 0.278 0.000
O80-O84 Delivery
0.722 0.278 0.000
T23 Burn and corrosion of wrist and hand
0.721 0.279 0.000
H25-H28 Disorders of lens
0.721 0.279 0.000
J21 Acute bronchiolitis
0.721 0.279 0.000
D84.9 Immunodeficiency, unspecified
0.720 0.280 0.000
F34 Persistent mood [affective] disorders
0.720 0.280 0.000
C60-C63 Malignant neoplasms of male genital organs
0.720 0.280 0.000
K50-K52 Noninfective enteritis and colitis
0.719 0.281 0.000
C79.2 Secondary malignant neoplasm of skin
0.719 0.281 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.719 0.281 0.000
C88.0 Waldenstrom's macroglobulinaemia
0.718 0.282 0.000
X10-X19 Contact with heat and hot substances
0.718 0.282 0.000
K50 Crohn's disease [regional enteritis]
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
O04 Medical abortion
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
M79.5 Residual foreign body in soft tissue
0.716 0.284 0.000
Y40 Systemic antibiotics
0.715 0.285 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.715 0.285 0.000
V80-V89 Other land transport accidents
0.715 0.285 0.000
M79.1 Myalgia
0.714 0.286 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.714 0.286 0.000
C94 Other leukaemias of specified cell type
0.714 0.286 0.000
C93 Monocytic leukaemia
0.714 0.286 0.000
C86 Other specified types of T/NK-cell lymphoma
0.714 0.286 0.000
M84 Disorders of continuity of bone
0.713 0.287 0.000
F42 Obsessive-compulsive disorder
0.712 0.288 0.000
M79.08 Rheumatism, unspecified (Other)
0.712 0.288 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.712 0.288 0.000
Q35-Q37 Cleft lip and cleft palate
0.712 0.288 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.712 0.288 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.710 0.289 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.710 0.289 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.710 0.289 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.710 0.289 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.710 0.289 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.710 0.289 0.000
M11 Other crystal arthropathies
0.709 0.291 0.000
O03 Spontaneous abortion
0.709 0.291 0.000
C71.0 Cerebrum, except lobes and ventricles
0.708 0.292 0.000
S09 Other and unspecified injuries of head
0.708 0.292 0.000
H25 Senile cataract
0.708 0.292 0.000
F50 Eating disorders
0.708 0.292 0.000
J81 Pulmonary oedema
0.708 0.292 0.000
F10.9 Unspecified mental and behavioural disorder
0.707 0.293 0.000
F10.8 Other mental and behavioural disorders
0.707 0.293 0.000
F10.7 Residual and late-onset psychotic disorder
0.707 0.293 0.000
F10.5 Psychotic disorder
0.707 0.293 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.707 0.293 0.000
O24 Diabetes mellitus in pregnancy
0.707 0.293 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.706 0.294 0.000
C83.3 Large cell (diffuse)
0.705 0.295 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.704 0.296 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.704 0.296 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.703 0.297 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.703 0.297 0.000
Chapter XXII Codes for special purposes
0.703 0.297 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.702 0.298 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.702 0.298 0.000
Y57 Other and unspecified drugs and medicaments
0.702 0.298 0.000
T36 Poisoning by systemic antibiotics
0.700 0.300 0.000
Q05 Spina bifida
0.700 0.300 0.000
S01.2 Open wound of nose
0.698 0.302 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.697 0.303 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.697 0.303 0.000
S08 Traumatic amputation of part of head
0.695 0.305 0.000
S07 Crushing injury of head
0.695 0.305 0.000
S04 Injury of cranial nerves
0.695 0.305 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.695 0.305 0.000
Y35-Y36 Legal intervention and operations of war
0.695 0.305 0.000
Y10-Y34 Event of undetermined intent
0.695 0.305 0.000
Y00-Y09 Assault
0.695 0.305 0.000
X85-X99 Assault
0.695 0.305 0.000
X30-X39 Exposure to forces of nature
0.695 0.305 0.000
X00-X09 Exposure to smoke, fire and flames
0.695 0.305 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.695 0.305 0.000
W75-W84 Other accidental threats to breathing
0.695 0.305 0.000
W65-W74 Accidental drowning and submersion
0.695 0.305 0.000
V98-V99 Other and unspecified transport accidents
0.695 0.305 0.000
V95-V97 Air and space transport accidents
0.695 0.305 0.000
V90-V94 Water transport accidents
0.695 0.305 0.000
V70-V79 Bus occupant injured in transport accident
0.695 0.305 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.695 0.305 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.695 0.305 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.695 0.305 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.695 0.305 0.000
K50.9 Crohn's disease, unspecified
0.695 0.305 0.000
F48 Other neurotic disorders
0.693 0.307 0.000
F44 Dissociative [conversion] disorders
0.693 0.307 0.000
D52.9 Folate deficiency anaemia, unspecified
0.693 0.307 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.692 0.308 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.692 0.308 0.000
H25.0 Senile incipient cataract
0.692 0.308 0.000
M91-M94 Chondropathies
0.691 0.308 0.000
D83 Common variable immunodeficiency
0.691 0.309 0.000
D82 Immunodeficiency associated with other major defects
0.691 0.309 0.000
D81 Combined immunodeficiencies
0.691 0.309 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.690 0.310 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.690 0.310 0.000
F38 Other mood [affective] disorders
0.689 0.311 0.000
F39 Unspecified mood [affective] disorder
0.689 0.311 0.000
Q61.2 Polycystic kidney, adult type
0.688 0.312 0.000
C91.8 Mature B-cell leukaemia Burkitt-type
0.688 0.312 0.000
C91.7 Other lymphoid leukaemia
0.688 0.312 0.000
C91.6 Prolymphocytic leukaemia of T-cell type
0.688 0.312 0.000
C91.5 Adult T-cell leukaemia
0.688 0.312 0.000
C91.4 Hairy-cell leukaemia
0.688 0.312 0.000
C91.3 Prolymphocytic leukaemia
0.688 0.312 0.000
C91.2 Subacute lymphocytic leukaemia
0.688 0.312 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.687 0.313 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.687 0.313 0.000
J44.1 Chronic obstructive pulmonary disease with acute exacerbation, unspecified
0.686 0.314 0.000
J90-J94 Other diseases of pleura
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
C67.2 Lateral wall of bladder
0.685 0.315 0.000
E70-E90 Metabolic disorders
0.685 0.315 0.000
D50 Iron deficiency anaemia
0.685 0.315 0.000
S20-S29 Injuries to the thorax
0.684 0.315 0.000
O03.4 Incomplete, without complication
0.684 0.316 0.000
M00-M03 Infectious arthropathies
0.684 0.316 0.000
F11 Mental and behavioural disorders due to use of opioids
0.684 0.316 0.000
C78.2 Secondary malignant neoplasm of pleura
0.684 0.316 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.683 0.317 0.000
S10-S19 Injuries to the neck
0.683 0.317 0.000
O04.9 Complete or unspecified, without complication
0.683 0.317 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.681 0.319 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.681 0.319 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.681 0.319 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.681 0.319 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.681 0.319 0.000
S02.4 Fracture of malar and maxillary bones
0.681 0.319 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.681 0.319 0.000
F45.3 Somatoform autonomic dysfunction
0.681 0.319 0.000
J84.9 Interstitial pulmonary disease, unspecified
0.681 0.319 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.680 0.320 0.000
O82 Single delivery by Caesarean section
0.680 0.320 0.000
Q63 Other congenital malformations of kidney
0.680 0.320 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.322 0.000
M12 Other specific arthropathies
0.678 0.322 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.322 0.000
M08 Juvenile arthritis
0.678 0.322 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.678 0.322 0.000
M54.4 Lumbago with sciatica
0.677 0.322 0.000
G93.9 Disorder of brain, unspecified
0.677 0.323 0.000
M79.2 Neuralgia and neuritis, unspecified
0.677 0.323 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.676 0.324 0.000
F32.8 Other depressive episodes
0.676 0.324 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.675 0.325 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.674 0.326 0.000
C71.8 Overlapping lesion of brain
0.674 0.326 0.000
K11 Diseases of salivary glands
0.674 0.326 0.000
J41 Simple and mucopurulent chronic bronchitis
0.674 0.326 0.000
T09 Other injuries of spine and trunk, level unspecified
0.674 0.326 0.000
T13 Other injuries of lower limb, level unspecified
0.674 0.326 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.673 0.327 0.000
S02.0 Fracture of vault of skull
0.673 0.327 0.000
T75 Effects of other external causes
0.672 0.328 0.000
T74 Maltreatment syndromes
0.672 0.328 0.000
T73 Effects of other deprivation
0.672 0.328 0.000
T70 Effects of air pressure and water pressure
0.672 0.328 0.000
T69 Other effects of reduced temperature
0.672 0.328 0.000
T67 Effects of heat and light
0.672 0.328 0.000
T71 Asphyxiation
0.672 0.328 0.000
T66 Unspecified effects of radiation
0.672 0.328 0.000
Q80-Q89 Other congenital malformations
0.672 0.328 0.000
F41.8 Other specified anxiety disorders
0.671 0.329 0.000
F41.3 Other mixed anxiety disorders
0.671 0.329 0.000
V49 Car occupant injured in other and unspecified transport accidents
0.670 0.330 0.000
T68 Hypothermia
0.670 0.330 0.000
G56 Mononeuropathies of upper limb
0.670 0.330 0.000
K76 Other diseases of liver
0.670 0.330 0.000
D80 Immunodeficiency with predominantly antibody defects
0.669 0.330 0.000
C72 Malignant neoplasm of spinal cord, cranial nerves and other parts of central nervous system
0.669 0.331 0.000
C70 Malignant neoplasm of meninges
0.669 0.331 0.000
S80-S89 Injuries to the knee and lower leg
0.669 0.331 0.000
Y48 Anaesthetics and therapeutic gases
0.668 0.332 0.000
F80-F89 Disorders of psychological development
0.668 0.332 0.000
Q24 Other congenital malformations of heart
0.668 0.332 0.000
O23 Infections of genito-urinary tract in pregnancy
0.668 0.332 0.000
M79.9 Soft tissue disorder, unspecified
0.667 0.332 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.667 0.333 0.000
M20-M25 Other joint disorders
0.667 0.333 0.000
M87 Osteonecrosis
0.667 0.333 0.000
S00.4 Superficial injury of ear
0.666 0.334 0.000
K50.1 Crohn's disease of large intestine
0.666 0.334 0.000
Q64 Other congenital malformations of urinary system
0.664 0.336 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.664 0.336 0.000
O82.0 Delivery by elective Caesarean section
0.664 0.336 0.000
X50-X57 Overexertion, travel and privation
0.664 0.336 0.000
M54.37 Sciatica (Lumbosacral region)
0.664 0.336 0.000
C91.0 Acute lymphoblastic leukaemia
0.663 0.337 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.663 0.337 0.000
S02.5 Fracture of tooth
0.663 0.337 0.000
S00.3 Superficial injury of nose
0.663 0.337 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.662 0.337 0.000
M89 Other disorders of bone
0.662 0.338 0.000
F45.8 Other somatoform disorders
0.662 0.338 0.000
Y59 Other and unspecified vaccines and biological substances
0.662 0.338 0.000
Y58 Bacterial vaccines
0.662 0.338 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.662 0.338 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.662 0.338 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.662 0.338 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.662 0.338 0.000
G70-G73 Diseases of myoneural junction and muscle
0.659 0.341 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.658 0.342 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.658 0.342 0.000
J20.9 Acute bronchitis, unspecified
0.658 0.342 0.000
T20 Burn and corrosion of head and neck
0.657 0.343 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.657 0.343 0.000
G56.2 Lesion of ulnar nerve
0.657 0.343 0.000
T43.9 Psychotropic drug, unspecified
0.657 0.343 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.657 0.343 0.000
T43.6 Psychostimulants with abuse potential
0.657 0.343 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.657 0.343 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.657 0.343 0.000
C92 Myeloid leukaemia
0.657 0.343 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.657 0.343 0.000
D86.3 Sarcoidosis of skin
0.656 0.344 0.000
D86.2 Sarcoidosis of lung with sarcoidosis of lymph nodes
0.656 0.344 0.000
D86.1 Sarcoidosis of lymph nodes
0.656 0.344 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.656 0.344 0.000
C48 Malignant neoplasm of retroperitoneum and peritoneum
0.656 0.344 0.000
E83 Disorders of mineral metabolism
0.655 0.345 0.000
S02.8 Fractures of other skull and facial bones
0.654 0.346 0.000
Q51.8 Other congenital malformations of uterus and cervix
0.654 0.346 0.000
D59.1 Other autoimmune haemolytic anaemias
0.654 0.346 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.653 0.346 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.653 0.347 0.000
M54.39 Sciatica (Site unspecified)
0.653 0.347 0.000
J11 Influenza, virus not identified
0.652 0.348 0.000
W20-W49 Exposure to inanimate mechanical forces
0.652 0.348 0.000
Q44 Congenital malformations of gallbladder, bile ducts and liver
0.652 0.348 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.651 0.349 0.000
W17 Other fall from one level to another
0.650 0.349 0.000
V17 Pedal cyclist injured in collision with fixed or stationary object
0.649 0.351 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.649 0.351 0.000
Q43.0 Meckel's diverticulum
0.649 0.351 0.000
T25 Burn and corrosion of ankle and foot
0.648 0.352 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.648 0.352 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.648 0.352 0.000
J95-J99 Other diseases of the respiratory system
0.648 0.352 0.000
M71 Other bursopathies
0.648 0.352 0.000
F10.4 Withdrawal state with delirium
0.647 0.353 0.000
K11.2 Sialoadenitis
0.647 0.353 0.000
G91 Hydrocephalus
0.647 0.353 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.647 0.353 0.000
M79.3 Panniculitis, unspecified
0.647 0.353 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.646 0.353 0.000
O21 Excessive vomiting in pregnancy
0.646 0.354 0.000
T14 Injury of unspecified body region
0.646 0.354 0.000
F99-F99 Unspecified mental disorder
0.645 0.355 0.000
K50.8 Other Crohn's disease
0.645 0.355 0.000
W10 Fall on and from stairs and steps
0.645 0.355 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.644 0.355 0.000
S02.7 Multiple fractures involving skull and facial bones
0.644 0.355 0.000
T24.0 Burn of unspecified degree of hip and lower limb, except ankle and foot
0.644 0.356 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.642 0.358 0.000
T90 Sequelae of injuries of head
0.642 0.358 0.000
T79.9 Unspecified early complication of trauma
0.642 0.358 0.000
T79.5 Traumatic anuria
0.642 0.358 0.000
T79.4 Traumatic shock
0.642 0.358 0.000
T79.2 Traumatic secondary and recurrent haemorrhage
0.642 0.358 0.000
T79.1 Fat embolism (traumatic)
0.642 0.358 0.000
T79.0 Air embolism (traumatic)
0.642 0.358 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.641 0.359 0.000
T78.9 Adverse effect, unspecified
0.641 0.359 0.000
Q61.3 Polycystic kidney, unspecified
0.641 0.359 0.000
C83.9 Diffuse non-Hodgkin's lymphoma, unspecified
0.641 0.359 0.000
C83.7 Burkitt's tumour
0.641 0.359 0.000
C83.6 Undifferentiated (diffuse)
0.641 0.359 0.000
C83.5 Lymphoblastic (diffuse)
0.641 0.359 0.000
C83.4 Immunoblastic (diffuse)
0.641 0.359 0.000
C83.2 Mixed small and large cell (diffuse)
0.641 0.359 0.000
M66 Spontaneous rupture of synovium and tendon
0.641 0.359 0.000
C49 Malignant neoplasm of other connective and soft tissue
0.641 0.359 0.000
J00-J06 Acute upper respiratory infections
0.641 0.359 0.000
C71.7 Brain stem
0.640 0.360 0.000
C71.6 Cerebellum
0.640 0.360 0.000
C71.5 Cerebral ventricle
0.640 0.360 0.000
C71.4 Occipital lobe
0.640 0.360 0.000
F60-F69 Disorders of adult personality and behaviour
0.640 0.360 0.000
D61 Other aplastic anaemias
0.639 0.361 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.639 0.361 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.639 0.361 0.000
M79.07 Rheumatism, unspecified (Ankle and foot)
0.638 0.362 0.000
M79.06 Rheumatism, unspecified (Lower leg)
0.638 0.362 0.000
M79.05 Rheumatism, unspecified (Pelvic region and thigh)
0.638 0.362 0.000
M79.04 Rheumatism, unspecified (Hand)
0.638 0.362 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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