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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12478336
log Bayes Factor = 13.7791
Chromosome 2   position 172,046,582  (GRCh37) Explore rs12478336 on Ensembl!
Variant rs12478336 is part of Cluster X0154

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XV Pregnancy, childbirth and the puerperium
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
O60-O75 Complications of labour and delivery
0.998 0.002 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.998 0.002 0.000
Chapter II Neoplasms
0.994 0.006 0.000
Z37 Outcome of delivery
0.985 0.015 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.971 0.029 0.000
Z37.0 Single live birth
0.970 0.030 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.968 0.032 0.000
Z30 Contraceptive management
0.967 0.033 0.000
M20-M25 Other joint disorders
0.959 0.041 0.000
S00-S09 Injuries to the head
0.948 0.052 0.000
C34 Malignant neoplasm of bronchus and lung
0.948 0.052 0.000
O48 Prolonged pregnancy
0.946 0.054 0.000
O68 Labour and delivery complicated by foetal stress [distress]
0.945 0.055 0.000
Z30.2 Sterilisation
0.944 0.056 0.000
Chapter I Certain infectious and parasitic diseases
0.941 0.059 0.000
O36 Maternal care for other known or suspected foetal problems
0.940 0.060 0.000
O70 Perineal laceration during delivery
0.937 0.063 0.000
Chapter VIII Diseases of the ear and mastoid process
0.936 0.064 0.000
M45-M49 Spondylopathies
0.935 0.065 0.000
Chapter XX External causes of morbidity and mortality
0.933 0.067 0.000
S20-S29 Injuries to the thorax
0.926 0.074 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.926 0.074 0.000
S80-S89 Injuries to the knee and lower leg
0.926 0.074 0.000
S50-S59 Injuries to the elbow and forearm
0.926 0.074 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.924 0.076 0.000
M50-M54 Other dorsopathies
0.923 0.077 0.000
Z45 Adjustment and management of implanted device
0.922 0.078 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.919 0.081 0.000
O72 Postpartum haemorrhage
0.918 0.082 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.913 0.087 0.000
O36.8 Maternal care for other specified foetal problems
0.904 0.096 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.904 0.096 0.000
M48 Other spondylopathies
0.899 0.101 0.000
Z45.8 Adjustment and management of other implanted devices
0.899 0.101 0.000
B95-B98 Bacterial, viral and other infectious agents
0.896 0.104 0.000
H90-H95 Other disorders of ear
0.896 0.104 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.895 0.105 0.000
Z53.9 Procedure not carried out, unspecified reason
0.890 0.110 0.000
C34.1 Upper lobe, bronchus or lung
0.887 0.113 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.880 0.120 0.000
M48.0 Spinal stenosis
0.874 0.126 0.000
M40-M43 Deforming dorsopathies
0.874 0.126 0.000
Z36 Antenatal screening
0.873 0.127 0.000
O68.2 Labour and delivery complicated by foetal heart rate anomaly with meconium in amniotic fluid
0.870 0.130 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.870 0.130 0.000
C51-C58 Malignant neoplasms of female genital organs
0.869 0.131 0.000
S52 Fracture of forearm
0.869 0.131 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.863 0.137 0.000
M70-M79 Other soft tissue disorders
0.859 0.141 0.000
S81 Open wound of lower leg
0.851 0.149 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.849 0.151 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.849 0.151 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.847 0.153 0.000
D00-D09 In situ neoplasms
0.845 0.154 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.845 0.155 0.000
O70.1 Second degree perineal laceration during delivery
0.840 0.160 0.000
O72.1 Other immediate postpartum haemorrhage
0.838 0.162 0.000
C34.3 Lower lobe, bronchus or lung
0.837 0.163 0.000
Z48 Other surgical follow-up care
0.834 0.166 0.000
S01 Open wound of head
0.833 0.167 0.000
C15-C26 Malignant neoplasms of digestive organs
0.833 0.167 0.000
M24 Other specific joint derangements
0.829 0.171 0.000
Z13 Special screening examination for other diseases and disorders
0.828 0.172 0.000
M31 Other necrotising vasculopathies
0.827 0.173 0.000
Z47 Other orthopaedic follow-up care
0.825 0.175 0.000
Chapter VI Diseases of the nervous system
0.825 0.175 0.000
M21 Other acquired deformities of limbs
0.824 0.176 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.824 0.176 0.000
M48.06 Spinal stenosis (Lumbar region)
0.824 0.176 0.000
Z35 Supervision of high-risk pregnancy
0.823 0.177 0.000
H92 Otalgia and effusion of ear
0.822 0.178 0.000
S20 Superficial injury of thorax
0.818 0.182 0.000
Z39 Postpartum care and examination
0.817 0.183 0.000
Chapter V Mental and behavioural disorders
0.815 0.185 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.814 0.186 0.000
M05-M14 Inflammatory polyarthropathies
0.813 0.187 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.813 0.187 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.813 0.187 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.812 0.188 0.000
D10-D36 Benign neoplasms
0.811 0.189 0.000
C56 Malignant neoplasm of ovary
0.811 0.189 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.810 0.190 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.810 0.190 0.000
H65-H75 Diseases of middle ear and mastoid
0.810 0.190 0.000
S02 Fracture of skull and facial bones
0.807 0.193 0.000
V10-V19 Pedal cyclist injured in transport accident
0.805 0.195 0.000
Z30.1 Insertion of (intra-uterine) contraceptive device
0.803 0.197 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.802 0.198 0.000
S00 Superficial injury of head
0.802 0.198 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.801 0.199 0.000
S40-S49 Injuries to the shoulder and upper arm
0.800 0.200 0.000
M25 Other joint disorders, not elsewhere classified
0.799 0.201 0.000
Z37.2 Twins, both liveborn
0.798 0.202 0.000
H91 Other hearing loss
0.797 0.203 0.000
O70.0 First degree perineal laceration during delivery
0.795 0.205 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.794 0.206 0.000
O73 Retained placenta and membranes, without haemorrhage
0.794 0.206 0.000
M54 Dorsalgia
0.793 0.207 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.790 0.210 0.000
O42 Premature rupture of membranes
0.790 0.210 0.000
C64-C68 Malignant neoplasms of urinary tract
0.786 0.214 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.784 0.216 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.780 0.220 0.000
M43 Other deforming dorsopathies
0.780 0.220 0.000
S80 Superficial injury of lower leg
0.780 0.220 0.000
S81.8 Open wound of other parts of lower leg
0.779 0.221 0.000
D05 Carcinoma in situ of breast
0.778 0.222 0.000
O68.0 Labour and delivery complicated by foetal heart rate anomaly
0.775 0.225 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.774 0.226 0.000
C34.9 Bronchus or lung, unspecified
0.773 0.227 0.000
T92 Sequelae of injuries of upper limb
0.772 0.228 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.768 0.232 0.000
G90-G99 Other disorders of the nervous system
0.765 0.235 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.764 0.236 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.763 0.237 0.000
T79-T79 Certain early complications of trauma
0.762 0.238 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.762 0.238 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.762 0.238 0.000
S10-S19 Injuries to the neck
0.761 0.239 0.000
S70-S79 Injuries to the hip and thigh
0.760 0.239 0.000
O66 Other obstructed labour
0.760 0.239 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.760 0.240 0.000
O68.9 Labour and delivery complicated by foetal stress, unspecified
0.759 0.241 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.759 0.241 0.000
M48.07 Spinal stenosis (Lumbosacral region)
0.755 0.245 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.754 0.246 0.000
Z47.8 Other specified orthopaedic follow-up care
0.754 0.246 0.000
Z42 Follow-up care involving plastic surgery
0.753 0.247 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.753 0.247 0.000
M80-M85 Disorders of bone density and structure
0.753 0.247 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.752 0.248 0.000
Z22 Carrier of infectious disease
0.748 0.252 0.000
D23 Other benign neoplasms of skin
0.748 0.252 0.000
S52.6 Fracture of lower end of both ulna and radius
0.747 0.253 0.000
S90-S99 Injuries to the ankle and foot
0.746 0.254 0.000
X60-X84 Intentional self-harm
0.746 0.254 0.000
T90 Sequelae of injuries of head
0.746 0.254 0.000
M86-M90 Other osteopathies
0.746 0.254 0.000
Z52 Donors of organs and tissues
0.745 0.255 0.000
S52.5 Fracture of lower end of radius
0.745 0.255 0.000
M53 Other dorsopathies, not elsewhere classified
0.744 0.256 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.743 0.257 0.000
M35 Other systemic involvement of connective tissue
0.742 0.258 0.000
M50 Cervical disk disorders
0.742 0.258 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.741 0.259 0.000
O99.8 Other specified diseases and conditions complicating pregnancy, childbirth and the puerperium
0.740 0.260 0.000
M79.6 Pain in limb
0.740 0.260 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.740 0.260 0.000
T43.2 Other and unspecified antidepressants
0.739 0.261 0.000
H92.0 Otalgia
0.739 0.261 0.000
Z08.0 Follow-up examination after surgery for malignant neoplasm
0.739 0.261 0.000
O34.2 Maternal care due to uterine scar from previous surgery
0.738 0.262 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.737 0.262 0.000
F30-F39 Mood [affective] disorders
0.737 0.263 0.000
W00-W19 Falls
0.735 0.265 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.735 0.265 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.734 0.266 0.000
M31.6 Other giant cell arteritis
0.732 0.268 0.000
O99.2 Endocrine, nutritional and metabolic diseases complicating pregnancy, childbirth and the puerperium
0.732 0.268 0.000
A00-A09 Intestinal infectious diseases
0.731 0.268 0.000
S20.8 Superficial injuries of other and unspecified parts of thorax
0.731 0.269 0.000
Z34 Supervision of normal pregnancy
0.730 0.270 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.730 0.270 0.000
M45 Ankylosing spondylitis
0.729 0.271 0.000
Z43 Attention to artificial openings
0.729 0.271 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.728 0.272 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.728 0.272 0.000
H91.9 Hearing loss, unspecified
0.727 0.273 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.726 0.274 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.726 0.274 0.000
T91 Sequelae of injuries of neck and trunk
0.724 0.276 0.000
S60-S69 Injuries to the wrist and hand
0.723 0.277 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.723 0.277 0.000
S01.9 Open wound of head, part unspecified
0.723 0.277 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.720 0.279 0.000
B35-B49 Mycoses
0.720 0.280 0.000
C18 Malignant neoplasm of colon
0.720 0.280 0.000
O47 False labour
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
O85-O92 Complications predominantly related to the puerperium
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z38 Liveborn infants according to place of birth
0.717 0.283 0.000
Z32 Pregnancy examination and test
0.717 0.283 0.000
Z31 Procreative management
0.717 0.283 0.000
C32 Malignant neoplasm of larynx
0.716 0.283 0.000
O63 Long labour
0.716 0.283 0.000
M91-M94 Chondropathies
0.716 0.284 0.000
M60-M63 Disorders of muscles
0.716 0.284 0.000
M00-M03 Infectious arthropathies
0.716 0.284 0.000
O74 Complications of anaesthesia during labour and delivery
0.716 0.284 0.000
O71 Other obstetric trauma
0.716 0.284 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.716 0.284 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.716 0.284 0.000
O61 Failed induction of labour
0.716 0.284 0.000
O60 Preterm delivery
0.716 0.284 0.000
Z45.1 Adjustment and management of infusion pump
0.716 0.284 0.000
O45 Premature separation of placenta [abruptio placentae]
0.715 0.285 0.000
O44 Placenta praevia
0.715 0.285 0.000
O43 Placental disorders
0.715 0.285 0.000
O41 Other disorders of amniotic fluid and membranes
0.715 0.285 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.715 0.285 0.000
O33 Maternal care for known or suspected disproportion
0.715 0.285 0.000
O31 Complications specific to multiple gestation
0.715 0.285 0.000
O40 Polyhydramnios
0.715 0.285 0.000
O72.0 Third-stage haemorrhage
0.714 0.286 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.714 0.286 0.000
S29 Other and unspecified injuries of thorax
0.713 0.287 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.713 0.287 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
M43.1 Spondylolisthesis
0.713 0.287 0.000
O00-O08 Pregnancy with abortive outcome
0.712 0.288 0.000
O70.2 Third degree perineal laceration during delivery
0.712 0.288 0.000
M13 Other arthritis
0.712 0.288 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.711 0.289 0.000
Z48.0 Attention to surgical dressings and sutures
0.710 0.290 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.709 0.290 0.000
Z37.9 Outcome of delivery unspecified
0.706 0.294 0.000
Z37.7 Other multiple births, all stillborn
0.706 0.294 0.000
Z37.6 Other multiple births, some liveborn
0.706 0.294 0.000
Z37.5 Other multiple births, all liveborn
0.706 0.294 0.000
Z37.4 Twins, both stillborn
0.706 0.294 0.000
Z37.3 Twins, one liveborn and one stillborn
0.706 0.294 0.000
Z37.1 Single stillbirth
0.706 0.294 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.706 0.294 0.000
O30 Multiple gestation
0.704 0.296 0.000
W20-W49 Exposure to inanimate mechanical forces
0.704 0.296 0.000
C34.0 Main bronchus
0.704 0.296 0.000
S06 Intracranial injury
0.703 0.297 0.000
Z36.9 Antenatal screening, unspecified
0.702 0.298 0.000
O36.6 Maternal care for excessive foetal growth
0.700 0.300 0.000
O46.9 Antepartum haemorrhage, unspecified
0.699 0.301 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.699 0.301 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.698 0.302 0.000
S32 Fracture of lumbar spine and pelvis
0.698 0.302 0.000
O62 Abnormalities of forces of labour
0.697 0.303 0.000
Z54 Convalescence
0.696 0.303 0.000
Z44 Fitting and adjustment of external prosthetic device
0.696 0.303 0.000
O42.1 Premature rupture of membranes, onset of labour after 24 hours
0.696 0.304 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.695 0.305 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.694 0.306 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.694 0.306 0.000
C31 Malignant neoplasm of accessory sinuses
0.694 0.306 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.694 0.306 0.000
C37 Malignant neoplasm of thymus
0.694 0.306 0.000
C33 Malignant neoplasm of trachea
0.694 0.306 0.000
Z30.9 Contraceptive management, unspecified
0.693 0.307 0.000
Z30.8 Other contraceptive management
0.693 0.307 0.000
Z30.4 Surveillance of contraceptive drugs
0.693 0.307 0.000
Z30.3 Menstrual extraction
0.693 0.307 0.000
Z30.0 General counselling and advice on contraception
0.693 0.307 0.000
Z53.2 Procedure not carried out because of patient's decision for other and unspecified reasons
0.693 0.307 0.000
M46 Other inflammatory spondylopathies
0.693 0.307 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.692 0.308 0.000
M65-M68 Disorders of synovium and tendon
0.691 0.309 0.000
M51 Other intervertebral disk disorders
0.690 0.310 0.000
O99.6 Diseases of the digestive system complicating pregnancy, childbirth and the puerperium
0.690 0.310 0.000
F32 Depressive episode
0.689 0.311 0.000
T66-T78 Other and unspecified effects of external causes
0.688 0.312 0.000
O99.0 Anaemia complicating pregnancy, childbirth and the puerperium
0.688 0.312 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.688 0.312 0.000
M34 Systemic sclerosis
0.688 0.312 0.000
M33 Dermatopolymyositis
0.688 0.312 0.000
M32 Systemic lupus erythematosus
0.688 0.312 0.000
M30 Polyarteritis nodosa and related conditions
0.688 0.312 0.000
S52.2 Fracture of shaft of ulna
0.686 0.314 0.000
Z39.1 Care and examination of lactating mother
0.685 0.315 0.000
Z36.8 Other antenatal screening
0.684 0.316 0.000
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm
0.684 0.316 0.000
D05.0 Lobular carcinoma in situ
0.683 0.317 0.000
A08 Viral and other specified intestinal infections
0.683 0.317 0.000
M24.8 Other specific joint derangements, not elsewhere classified
0.682 0.317 0.000
S80.8 Other superficial injuries of lower leg
0.682 0.318 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.681 0.319 0.000
O72.2 Delayed and secondary postpartum haemorrhage
0.681 0.319 0.000
Z49 Care involving dialysis
0.681 0.319 0.000
T92.0 Sequelae of open wound of upper limb
0.680 0.320 0.000
A80-A89 Viral infections of the central nervous system
0.680 0.320 0.000
Z36.3 Antenatal screening for malformations using ultrasound and other physical methods
0.680 0.320 0.000
M24.1 Other articular cartilage disorders
0.680 0.320 0.000
S08 Traumatic amputation of part of head
0.679 0.320 0.000
S07 Crushing injury of head
0.679 0.320 0.000
S05 Injury of eye and orbit
0.679 0.320 0.000
S04 Injury of cranial nerves
0.679 0.320 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.679 0.320 0.000
S01.0 Open wound of scalp
0.679 0.320 0.000
C34.8 Overlapping lesion of bronchus and lung
0.679 0.321 0.000
C34.2 Middle lobe, bronchus or lung
0.679 0.321 0.000
T31 Burns classified according to extent of body surface involved
0.679 0.321 0.000
O68.8 Labour and delivery complicated by other evidence of foetal stress
0.678 0.322 0.000
S51 Open wound of forearm
0.678 0.322 0.000
O68.3 Labour and delivery complicated by biochemical evidence of foetal stress
0.677 0.322 0.000
Z22.3 Carrier of other specified bacterial diseases
0.676 0.324 0.000
O34.1 Maternal care for tumour of corpus uteri
0.675 0.325 0.000
D23.5 Skin of trunk
0.675 0.325 0.000
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts
0.674 0.325 0.000
S27 Injury of other and unspecified intrathoracic organs
0.674 0.326 0.000
B99-B99 Other infectious diseases
0.674 0.326 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.674 0.326 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.674 0.326 0.000
B65-B83 Helminthiases
0.674 0.326 0.000
B50-B64 Protozoal diseases
0.674 0.326 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.674 0.326 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.674 0.326 0.000
A75-A79 Rickettsioses
0.674 0.326 0.000
A70-A74 Other diseases caused by chlamydiae
0.674 0.326 0.000
A65-A69 Other spirochaetal diseases
0.674 0.326 0.000
A20-A28 Certain zoonotic bacterial diseases
0.674 0.326 0.000
A15-A19 Tuberculosis
0.674 0.326 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.674 0.326 0.000
O36.9 Maternal care for foetal problem, unspecified
0.674 0.326 0.000
O36.7 Maternal care for viable foetus in abdominal pregnancy
0.674 0.326 0.000
O36.4 Maternal care for intra-uterine death
0.674 0.326 0.000
O36.3 Maternal care for signs of foetal hypoxia
0.674 0.326 0.000
O36.2 Maternal care for hydrops foetalis
0.674 0.326 0.000
O36.1 Maternal care for other isoimmunisation
0.674 0.326 0.000
D10 Benign neoplasm of mouth and pharynx
0.673 0.327 0.000
H92.1 Otorrhoea
0.673 0.327 0.000
S52.0 Fracture of upper end of ulna
0.672 0.328 0.000
O70.9 Perineal laceration during delivery, unspecified
0.672 0.328 0.000
O70.3 Fourth degree perineal laceration during delivery
0.672 0.328 0.000
B15-B19 Viral hepatitis
0.671 0.329 0.000
M21.0 Valgus deformity, not elsewhere classified
0.671 0.329 0.000
M48.09 Spinal stenosis (Site unspecified)
0.671 0.329 0.000
M49 Spondylopathies in diseases classified elsewhere
0.670 0.329 0.000
S42 Fracture of shoulder and upper arm
0.670 0.330 0.000
D16 Benign neoplasm of bone and articular cartilage
0.670 0.330 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.669 0.331 0.000
Y35-Y36 Legal intervention and operations of war
0.669 0.331 0.000
Y10-Y34 Event of undetermined intent
0.669 0.331 0.000
Y00-Y09 Assault
0.669 0.331 0.000
X85-X99 Assault
0.669 0.331 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.669 0.331 0.000
X50-X57 Overexertion, travel and privation
0.669 0.331 0.000
X30-X39 Exposure to forces of nature
0.669 0.331 0.000
X20-X29 Contact with venomous animals and plants
0.669 0.331 0.000
X10-X19 Contact with heat and hot substances
0.669 0.331 0.000
X00-X09 Exposure to smoke, fire and flames
0.669 0.331 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.669 0.331 0.000
W75-W84 Other accidental threats to breathing
0.669 0.331 0.000
W65-W74 Accidental drowning and submersion
0.669 0.331 0.000
W50-W64 Exposure to animate mechanical forces
0.669 0.331 0.000
V98-V99 Other and unspecified transport accidents
0.669 0.331 0.000
V95-V97 Air and space transport accidents
0.669 0.331 0.000
V90-V94 Water transport accidents
0.669 0.331 0.000
V80-V89 Other land transport accidents
0.669 0.331 0.000
V70-V79 Bus occupant injured in transport accident
0.669 0.331 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.669 0.331 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.669 0.331 0.000
V40-V49 Car occupant injured in transport accident
0.669 0.331 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.669 0.331 0.000
V01-V09 Pedestrian injured in transport accident
0.669 0.331 0.000
S01.3 Open wound of ear
0.668 0.332 0.000
M20 Acquired deformities of fingers and toes
0.668 0.332 0.000
C80 Malignant neoplasm without specification of site
0.667 0.333 0.000
C50-C50 Malignant neoplasm of breast
0.665 0.335 0.000
V20-V29 Motorcycle rider injured in transport accident
0.664 0.336 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.664 0.336 0.000
S26 Injury of heart
0.664 0.336 0.000
S25 Injury of blood vessels of thorax
0.664 0.336 0.000
S24 Injury of nerves and spinal cord at thorax level
0.664 0.336 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.664 0.336 0.000
S21 Open wound of thorax
0.664 0.336 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.664 0.336 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.664 0.336 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.664 0.336 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.664 0.336 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.664 0.336 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.664 0.336 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.664 0.336 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
T36 Poisoning by systemic antibiotics
0.664 0.336 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.664 0.336 0.000
S59 Other and unspecified injuries of forearm
0.664 0.336 0.000
S58 Traumatic amputation of forearm
0.664 0.336 0.000
S57 Crushing injury of forearm
0.664 0.336 0.000
S56 Injury of muscle and tendon at forearm level
0.664 0.336 0.000
S55 Injury of blood vessels at forearm level
0.664 0.336 0.000
S54 Injury of nerves at forearm level
0.664 0.336 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.664 0.336 0.000
S50 Superficial injury of forearm
0.664 0.336 0.000
S89 Other and unspecified injuries of lower leg
0.664 0.336 0.000
S88 Traumatic amputation of lower leg
0.664 0.336 0.000
S87 Crushing injury of lower leg
0.664 0.336 0.000
S86 Injury of muscle and tendon at lower leg level
0.664 0.336 0.000
S85 Injury of blood vessels at lower leg level
0.664 0.336 0.000
S84 Injury of nerves at lower leg level
0.664 0.336 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.663 0.336 0.000
C18.7 Sigmoid colon
0.663 0.337 0.000
O98 Maternal infectious and parasitic diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.662 0.337 0.000
O97 Death from sequelae of direct obstetric causes
0.662 0.337 0.000
O96 Death from any obstetric cause occurring more than 42 days but less than one year after delivery
0.662 0.337 0.000
O95 Obstetric death of unspecified cause
0.662 0.337 0.000
O94 Sequelae of complication of pregnancy, childbirth and the puerperium
0.662 0.337 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.661 0.339 0.000
Z45.3 Adjustment and management of implanted hearing device
0.661 0.339 0.000
M77 Other enthesopathies
0.660 0.340 0.000
F32.9 Depressive episode, unspecified
0.660 0.340 0.000
Z33 Pregnant state, incidental
0.660 0.340 0.000
S52.60 Fracture of lower end of both ulna and radius (closed)
0.660 0.340 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.659 0.341 0.000
M54.4 Lumbago with sciatica
0.659 0.341 0.000
T98 Sequelae of other and unspecified effects of external causes
0.659 0.341 0.000
T95 Sequelae of burns, corrosions and frostbite
0.659 0.341 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.659 0.341 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.659 0.341 0.000
O72.3 Postpartum coagulation defects
0.658 0.342 0.000
H65 Nonsuppurative otitis media
0.658 0.342 0.000
S00.8 Superficial injury of other parts of head
0.657 0.343 0.000
M76 Enthesopathies of lower limb, excluding foot
0.656 0.343 0.000
S52.50 Fracture of lower end of radius (closed)
0.656 0.344 0.000
M25.8 Other specified joint disorders
0.656 0.344 0.000
D05.1 Intraductal carcinoma in situ
0.656 0.344 0.000
Z36.0 Antenatal screening for chromosomal anomalies
0.655 0.344 0.000
M22 Disorders of patella
0.655 0.345 0.000
T87 Complications peculiar to reattachment and amputation
0.654 0.345 0.000
T86 Failure and rejection of transplanted organs and tissues
0.654 0.345 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.654 0.345 0.000
M21.1 Varus deformity, not elsewhere classified
0.654 0.346 0.000
O36.5 Maternal care for poor foetal growth
0.654 0.346 0.000
M79.66 Pain in limb (Lower leg)
0.653 0.347 0.000
G95 Other diseases of spinal cord
0.652 0.348 0.000
S81.9 Open wound of lower leg, part unspecified
0.652 0.348 0.000
M79.0 Rheumatism, unspecified
0.651 0.349 0.000
Z48.9 Surgical follow-up care, unspecified
0.650 0.350 0.000
H93 Other disorders of ear, not elsewhere classified
0.648 0.352 0.000
O73.0 Retained placenta, without haemorrhage
0.648 0.352 0.000
Z53.1 Procedure not carried out because of patient's decision for reasons of belief or group pressure
0.648 0.352 0.000
M48.02 Spinal stenosis (Cervical region)
0.647 0.352 0.000
G93 Other disorders of brain
0.645 0.355 0.000
D23.1 Skin of eyelid, including canthus
0.645 0.355 0.000
M48.9 Spondylopathy, unspecified
0.645 0.355 0.000
M48.8 Other specified spondylopathies
0.645 0.355 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.645 0.355 0.000
M48.4 Fatigue fracture of vertebra
0.645 0.355 0.000
M48.3 Traumatic spondylopathy
0.645 0.355 0.000
M48.2 Kissing spine
0.645 0.355 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.645 0.355 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.645 0.355 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.645 0.355 0.000
H72 Perforation of tympanic membrane
0.644 0.356 0.000
C45 Mesothelioma
0.644 0.356 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.643 0.357 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.642 0.358 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.642 0.358 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.642 0.358 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.641 0.359 0.000
S37 Injury of urinary and pelvic organs
0.641 0.359 0.000
S36 Injury of intra-abdominal organs
0.641 0.359 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.641 0.359 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.641 0.359 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.641 0.359 0.000
S31 Open wound of abdomen, lower back and pelvis
0.641 0.359 0.000
H69 Other disorders of Eustachian tube
0.641 0.359 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.641 0.359 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.641 0.359 0.000
M21.6 Other acquired deformities of ankle and foot
0.641 0.359 0.000
B25-B34 Other viral diseases
0.640 0.360 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.640 0.360 0.000
M54.2 Cervicalgia
0.640 0.360 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.639 0.360 0.000
Z43.6 Attention to other artificial openings of urinary tract
0.638 0.362 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.637 0.363 0.000
M41 Scoliosis
0.637 0.363 0.000
M13.9 Arthritis, unspecified
0.636 0.364 0.000
Z50 Care involving use of rehabilitation procedures
0.636 0.364 0.000
D22 Melanocytic naevi
0.634 0.366 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.634 0.366 0.000
Z42.3 Follow-up care involving plastic surgery of upper extremity
0.634 0.366 0.000
H90 Conductive and sensorineural hearing loss
0.633 0.367 0.000
O68.1 Labour and delivery complicated by meconium in amniotic fluid
0.633 0.367 0.000
S22.0 Fracture of thoracic vertebra
0.633 0.367 0.000
D11 Benign neoplasm of major salivary glands
0.633 0.367 0.000
O23 Infections of genito-urinary tract in pregnancy
0.632 0.368 0.000
S81.0 Open wound of knee
0.632 0.368 0.000
S02.8 Fractures of other skull and facial bones
0.632 0.368 0.000
O32.1 Maternal care for breech presentation
0.631 0.369 0.000
M54.9 Dorsalgia, unspecified
0.631 0.369 0.000
D04 Carcinoma in situ of skin
0.631 0.369 0.000
Z10 Routine general health check-up of defined subpopulation
0.631 0.369 0.000
M79.7 Fibromyalgia
0.631 0.369 0.000
M79.62 Pain in limb (Upper arm)
0.631 0.369 0.000
G20-G26 Extrapyramidal and movement disorders
0.631 0.369 0.000
S01.1 Open wound of eyelid and periocular area
0.630 0.369 0.000
D03 Melanoma in situ
0.630 0.370 0.000
T93 Sequelae of injuries of lower limb
0.629 0.370 0.000
S02.0 Fracture of vault of skull
0.629 0.371 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.628 0.372 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

This website was created, designed, and edited by ORCID iD iconPatrick K. Albers

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