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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs12772609
log Bayes Factor = 14.1883
Chromosome 10   position 126,378,406  (GRCh37) Explore rs12772609 on Ensembl!
Variant rs12772609 is part of Cluster X0204

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I30-I52 Other forms of heart disease
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
Chapter XIV Diseases of the genitourinary system
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.992 0.008 0.000
I50 Heart failure
0.991 0.009 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.985 0.015 0.000
Chapter V Mental and behavioural disorders
0.982 0.018 0.000
G40-G47 Episodic and paroxysmal disorders
0.980 0.020 0.000
I50.1 Left ventricular failure
0.976 0.024 0.000
N17-N19 Renal failure
0.976 0.024 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.975 0.025 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.970 0.030 0.000
I49 Other cardiac arrhythmias
0.964 0.036 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.964 0.036 0.000
Chapter XX External causes of morbidity and mortality
0.964 0.036 0.000
N18 Chronic renal failure
0.963 0.037 0.000
I45 Other conduction disorders
0.955 0.045 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.955 0.045 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.953 0.047 0.000
S80-S89 Injuries to the knee and lower leg
0.952 0.048 0.000
I51 Complications and ill-defined descriptions of heart disease
0.947 0.053 0.000
S00-S09 Injuries to the head
0.946 0.054 0.000
I47 Paroxysmal tachycardia
0.945 0.055 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.928 0.072 0.000
G40 Epilepsy
0.927 0.073 0.000
I51.8 Other ill-defined heart diseases
0.925 0.075 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.922 0.078 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.921 0.079 0.000
Q60-Q64 Congenital malformations of the urinary system
0.914 0.086 0.000
N18.9 Chronic renal failure, unspecified
0.913 0.087 0.000
Chapter II Neoplasms
0.911 0.089 0.000
L40-L45 Papulosquamous disorders
0.910 0.090 0.000
I21 Acute myocardial infarction
0.910 0.090 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.909 0.091 0.000
G20-G26 Extrapyramidal and movement disorders
0.909 0.091 0.000
I47.2 Ventricular tachycardia
0.908 0.092 0.000
I20 Angina pectoris
0.908 0.092 0.000
G30-G32 Other degenerative diseases of the nervous system
0.905 0.095 0.000
G90-G99 Other disorders of the nervous system
0.897 0.103 0.000
S00 Superficial injury of head
0.895 0.105 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.890 0.110 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.887 0.113 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.885 0.115 0.000
N18.0 End-stage renal disease
0.879 0.121 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.878 0.122 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.877 0.123 0.000
N00-N08 Glomerular diseases
0.875 0.125 0.000
Q61 Cystic kidney disease
0.873 0.127 0.000
Chapter XXII Codes for special purposes
0.862 0.138 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.857 0.143 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.856 0.144 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.856 0.144 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.854 0.146 0.000
I35 Nonrheumatic aortic valve disorders
0.852 0.148 0.000
T86 Failure and rejection of transplanted organs and tissues
0.850 0.150 0.000
I49.8 Other specified cardiac arrhythmias
0.850 0.150 0.000
I45.6 Preexcitation syndrome
0.850 0.150 0.000
I49.4 Other and unspecified premature depolarisation
0.849 0.151 0.000
S82 Fracture of lower leg, including ankle
0.846 0.154 0.000
L20-L30 Dermatitis and eczema
0.842 0.158 0.000
F22 Persistent delusional disorders
0.842 0.158 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.840 0.160 0.000
R47-R49 Symptoms and signs involving speech and voice
0.837 0.163 0.000
I31 Other diseases of pericardium
0.837 0.163 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.836 0.164 0.000
N25-N29 Other disorders of kidney and ureter
0.835 0.165 0.000
N10-N16 Renal tubulo-interstitial diseases
0.833 0.167 0.000
S50-S59 Injuries to the elbow and forearm
0.832 0.168 0.000
I45.8 Other specified conduction disorders
0.831 0.169 0.000
I42 Cardiomyopathy
0.829 0.171 0.000
F29 Unspecified nonorganic psychosis
0.828 0.172 0.000
F20 Schizophrenia
0.827 0.173 0.000
I25.5 Ischaemic cardiomyopathy
0.826 0.174 0.000
X60-X84 Intentional self-harm
0.826 0.174 0.000
I49.5 Sick sinus syndrome
0.823 0.177 0.000
N40-N51 Diseases of male genital organs
0.822 0.178 0.000
R41.0 Disorientation, unspecified
0.821 0.179 0.000
L40 Psoriasis
0.820 0.180 0.000
S80 Superficial injury of lower leg
0.817 0.183 0.000
F10.1 Harmful use
0.816 0.184 0.000
I34 Nonrheumatic mitral valve disorders
0.814 0.186 0.000
C15-C26 Malignant neoplasms of digestive organs
0.813 0.187 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.809 0.191 0.000
G40.9 Epilepsy, unspecified
0.808 0.192 0.000
I50.9 Heart failure, unspecified
0.808 0.192 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.805 0.195 0.000
S32 Fracture of lumbar spine and pelvis
0.802 0.198 0.000
G25 Other extrapyramidal and movement disorders
0.802 0.198 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.800 0.200 0.000
S00.8 Superficial injury of other parts of head
0.800 0.200 0.000
I50.0 Congestive heart failure
0.798 0.202 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.795 0.205 0.000
I45.9 Conduction disorder, unspecified
0.794 0.205 0.000
O00-O08 Pregnancy with abortive outcome
0.794 0.206 0.000
N48 Other disorders of penis
0.793 0.207 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.792 0.208 0.000
S00.1 Contusion of eyelid and periocular area
0.792 0.208 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.791 0.209 0.000
Y40 Systemic antibiotics
0.790 0.210 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.787 0.213 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.787 0.213 0.000
V98-V99 Other and unspecified transport accidents
0.787 0.213 0.000
Q61.3 Polycystic kidney, unspecified
0.786 0.214 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.785 0.215 0.000
S70-S79 Injuries to the hip and thigh
0.782 0.218 0.000
I44 Atrioventricular and left bundle-branch block
0.781 0.219 0.000
L43 Lichen planus
0.779 0.221 0.000
S81 Open wound of lower leg
0.779 0.221 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.777 0.223 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.775 0.225 0.000
N18.3 Chronic kidney disease, stage 3
0.773 0.227 0.000
I20.1 Angina pectoris with documented spasm
0.773 0.227 0.000
N48.4 Impotence of organic origin
0.771 0.229 0.000
R45 Symptoms and signs involving emotional state
0.771 0.229 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.769 0.231 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.769 0.231 0.000
F60-F69 Disorders of adult personality and behaviour
0.768 0.232 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.767 0.233 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.767 0.233 0.000
F99-F99 Unspecified mental disorder
0.767 0.233 0.000
I36 Nonrheumatic tricuspid valve disorders
0.767 0.233 0.000
N99-N99 Other disorders of the genitourinary system
0.766 0.234 0.000
S01 Open wound of head
0.765 0.235 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.764 0.236 0.000
Y52 Agents primarily affecting the cardiovascular system
0.763 0.237 0.000
F22.0 Delusional disorder
0.763 0.237 0.000
C51-C58 Malignant neoplasms of female genital organs
0.763 0.237 0.000
N19 Unspecified renal failure
0.762 0.238 0.000
I45.5 Other specified heart block
0.762 0.238 0.000
S82.8 Fractures of other parts of lower leg
0.761 0.239 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.761 0.239 0.000
I30 Acute pericarditis
0.758 0.241 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.758 0.242 0.000
N18.5 Chronic kidney disease, stage 5
0.757 0.243 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.757 0.243 0.000
F80-F89 Disorders of psychological development
0.756 0.244 0.000
G40.5 Special epileptic syndromes
0.754 0.246 0.000
L27 Dermatitis due to substances taken internally
0.754 0.246 0.000
I25.3 Aneurysm of heart
0.753 0.247 0.000
G20 Parkinson's disease
0.753 0.247 0.000
R47 Speech disturbances, not elsewhere classified
0.753 0.247 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.752 0.248 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.752 0.248 0.000
T82.1 Mechanical complication of cardiac electronic device
0.750 0.249 0.000
I33 Acute and subacute endocarditis
0.748 0.252 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.748 0.252 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.744 0.255 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.744 0.256 0.000
G70-G73 Diseases of myoneural junction and muscle
0.743 0.257 0.000
S06 Intracranial injury
0.743 0.257 0.000
N02 Recurrent and persistent haematuria
0.743 0.257 0.000
G45.4 Transient global amnesia
0.743 0.257 0.000
O60-O75 Complications of labour and delivery
0.742 0.258 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.742 0.258 0.000
I34.0 Mitral (valve) insufficiency
0.741 0.259 0.000
G93 Other disorders of brain
0.741 0.259 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.740 0.260 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.739 0.261 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.739 0.261 0.000
R20 Disturbances of skin sensation
0.737 0.263 0.000
L57 Skin changes due to chronic exposure to nonionising radiation
0.736 0.264 0.000
Q61.9 Cystic kidney disease, unspecified
0.735 0.265 0.000
C15 Malignant neoplasm of oesophagus
0.735 0.265 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.735 0.265 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.735 0.265 0.000
O02 Other abnormal products of conception
0.734 0.266 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.734 0.266 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.733 0.267 0.000
G41 Status epilepticus
0.733 0.267 0.000
I20.8 Other forms of angina pectoris
0.733 0.267 0.000
N20-N23 Urolithiasis
0.732 0.268 0.000
G30 Alzheimer's disease
0.732 0.268 0.000
Q50-Q56 Congenital malformations of genital organs
0.731 0.269 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.730 0.270 0.000
C18 Malignant neoplasm of colon
0.729 0.271 0.000
W50-W64 Exposure to animate mechanical forces
0.729 0.271 0.000
T79-T79 Certain early complications of trauma
0.727 0.273 0.000
T86.1 Kidney transplant failure and rejection
0.727 0.273 0.000
I49.9 Cardiac arrhythmia, unspecified
0.727 0.273 0.000
Q61.2 Polycystic kidney, adult type
0.726 0.274 0.000
I35.1 Aortic (valve) insufficiency
0.726 0.274 0.000
W20-W49 Exposure to inanimate mechanical forces
0.726 0.274 0.000
S05 Injury of eye and orbit
0.725 0.275 0.000
T87 Complications peculiar to reattachment and amputation
0.724 0.276 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.724 0.276 0.000
I10-I15 Hypertensive diseases
0.724 0.276 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.721 0.279 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.721 0.279 0.000
G91 Hydrocephalus
0.720 0.280 0.000
X20-X29 Contact with venomous animals and plants
0.719 0.281 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.719 0.281 0.000
F23 Acute and transient psychotic disorders
0.718 0.281 0.000
L40.9 Psoriasis, unspecified
0.718 0.282 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.717 0.283 0.000
I52 Other heart disorders in diseases classified elsewhere
0.717 0.283 0.000
I48 Atrial fibrillation and flutter
0.717 0.283 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.717 0.283 0.000
I41 Myocarditis in diseases classified elsewhere
0.717 0.283 0.000
I40 Acute myocarditis
0.717 0.283 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.717 0.283 0.000
I37 Pulmonary valve disorders
0.717 0.283 0.000
I32 Pericarditis in diseases classified elsewhere
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.717 0.283 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.716 0.284 0.000
R30-R39 Symptoms and signs involving the urinary system
0.715 0.285 0.000
L60-L75 Disorders of skin appendages
0.715 0.285 0.000
S00.0 Superficial injury of scalp
0.715 0.285 0.000
Y40.0 Penicillins
0.713 0.287 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.713 0.287 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.712 0.288 0.000
I49.0 Ventricular fibrillation and flutter
0.712 0.288 0.000
I25.6 Silent myocardial ischaemia
0.711 0.289 0.000
I25.4 Coronary artery aneurysm
0.711 0.289 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.711 0.289 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.711 0.289 0.000
O42 Premature rupture of membranes
0.711 0.289 0.000
R42 Dizziness and giddiness
0.710 0.290 0.000
N03 Chronic nephritic syndrome
0.709 0.291 0.000
V80-V89 Other land transport accidents
0.708 0.292 0.000
V20-V29 Motorcycle rider injured in transport accident
0.708 0.292 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.706 0.294 0.000
G43 Migraine
0.705 0.295 0.000
D10-D36 Benign neoplasms
0.704 0.296 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.704 0.296 0.000
F70-F79 Mental retardation
0.704 0.296 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.703 0.297 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.703 0.297 0.000
I20.9 Angina pectoris, unspecified
0.702 0.298 0.000
N41 Inflammatory diseases of prostate
0.701 0.298 0.000
S90-S99 Injuries to the ankle and foot
0.701 0.299 0.000
N42 Other disorders of prostate
0.700 0.300 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.700 0.300 0.000
S00.3 Superficial injury of nose
0.699 0.301 0.000
L10-L14 Bullous disorders
0.699 0.301 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.699 0.301 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.697 0.303 0.000
N18.4 Chronic kidney disease, stage 4
0.696 0.304 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.695 0.304 0.000
Q80-Q89 Other congenital malformations
0.695 0.304 0.000
Q35-Q37 Cleft lip and cleft palate
0.695 0.304 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.695 0.304 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.695 0.304 0.000
N10 Acute tubulo-interstitial nephritis
0.694 0.306 0.000
N48.9 Disorder of penis, unspecified
0.693 0.307 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.693 0.307 0.000
F20.0 Paranoid schizophrenia
0.693 0.307 0.000
O02.1 Missed abortion
0.691 0.309 0.000
I49.2 Junctional premature depolarisation
0.691 0.309 0.000
I49.1 Atrial premature depolarisation
0.691 0.309 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.691 0.309 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.691 0.309 0.000
Y35-Y36 Legal intervention and operations of war
0.691 0.309 0.000
Y10-Y34 Event of undetermined intent
0.691 0.309 0.000
Y00-Y09 Assault
0.691 0.309 0.000
X85-X99 Assault
0.691 0.309 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.691 0.309 0.000
X50-X57 Overexertion, travel and privation
0.691 0.309 0.000
X30-X39 Exposure to forces of nature
0.691 0.309 0.000
X10-X19 Contact with heat and hot substances
0.691 0.309 0.000
X00-X09 Exposure to smoke, fire and flames
0.691 0.309 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.691 0.309 0.000
W75-W84 Other accidental threats to breathing
0.691 0.309 0.000
W65-W74 Accidental drowning and submersion
0.691 0.309 0.000
V95-V97 Air and space transport accidents
0.691 0.309 0.000
V90-V94 Water transport accidents
0.691 0.309 0.000
V70-V79 Bus occupant injured in transport accident
0.691 0.309 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.691 0.309 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.691 0.309 0.000
V40-V49 Car occupant injured in transport accident
0.691 0.309 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.691 0.309 0.000
V01-V09 Pedestrian injured in transport accident
0.691 0.309 0.000
N18.8 Other chronic renal failure
0.691 0.309 0.000
N18.1 Chronic kidney disease, stage 1
0.691 0.309 0.000
Q00-Q07 Congenital malformations of the nervous system
0.690 0.310 0.000
S89 Other and unspecified injuries of lower leg
0.690 0.310 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.688 0.312 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.688 0.312 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.687 0.313 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.687 0.313 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.687 0.313 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.686 0.314 0.000
R32 Unspecified urinary incontinence
0.685 0.315 0.000
T86.0 Bone-marrow transplant rejection
0.685 0.315 0.000
I45.4 Nonspecific intraventricular block
0.685 0.315 0.000
I45.3 Trifascicular block
0.685 0.315 0.000
I45.2 Bifascicular block
0.685 0.315 0.000
I45.0 Right fascicular block
0.685 0.315 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.685 0.315 0.000
L43.9 Lichen planus, unspecified
0.684 0.316 0.000
Y57 Other and unspecified drugs and medicaments
0.684 0.316 0.000
F25 Schizoaffective disorders
0.683 0.317 0.000
F28 Other nonorganic psychotic disorders
0.683 0.317 0.000
F24 Induced delusional disorder
0.683 0.317 0.000
F21 Schizotypal disorder
0.683 0.317 0.000
S88 Traumatic amputation of lower leg
0.683 0.317 0.000
S87 Crushing injury of lower leg
0.683 0.317 0.000
S86 Injury of muscle and tendon at lower leg level
0.683 0.317 0.000
S85 Injury of blood vessels at lower leg level
0.683 0.317 0.000
S84 Injury of nerves at lower leg level
0.683 0.317 0.000
I20.0 Unstable angina
0.682 0.318 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.681 0.318 0.000
F10.4 Withdrawal state with delirium
0.681 0.319 0.000
I31.9 Disease of pericardium, unspecified
0.680 0.320 0.000
I51.6 Cardiovascular disease, unspecified
0.679 0.321 0.000
I51.5 Myocardial degeneration
0.679 0.321 0.000
I51.4 Myocarditis, unspecified
0.679 0.321 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.679 0.321 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.679 0.321 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.679 0.321 0.000
I51.0 Cardiac septal defect, acquired
0.679 0.321 0.000
G83 Other paralytic syndromes
0.679 0.321 0.000
S08 Traumatic amputation of part of head
0.678 0.322 0.000
S07 Crushing injury of head
0.678 0.322 0.000
S04 Injury of cranial nerves
0.678 0.322 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.678 0.322 0.000
Y43 Primarily systemic agents
0.678 0.322 0.000
I47.0 Reentry ventricular arrhythmia
0.677 0.322 0.000
S80.8 Other superficial injuries of lower leg
0.677 0.322 0.000
I51.9 Heart disease, unspecified
0.677 0.323 0.000
G45.3 Amaurosis fugax
0.677 0.323 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.675 0.325 0.000
S02 Fracture of skull and facial bones
0.675 0.325 0.000
S52 Fracture of forearm
0.674 0.326 0.000
G96 Other disorders of central nervous system
0.674 0.326 0.000
G44 Other headache syndromes
0.673 0.327 0.000
T66-T78 Other and unspecified effects of external causes
0.672 0.327 0.000
R94 Abnormal results of function studies
0.672 0.328 0.000
G82 Paraplegia and tetraplegia
0.672 0.328 0.000
R47.8 Other and unspecified speech disturbances
0.671 0.329 0.000
R20.2 Paraesthesia of skin
0.670 0.330 0.000
F20.9 Schizophrenia, unspecified
0.669 0.331 0.000
R45.1 Restlessness and agitation
0.669 0.331 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.668 0.332 0.000
N20 Calculus of kidney and ureter
0.667 0.333 0.000
S82.2 Fracture of shaft of tibia
0.666 0.334 0.000
R23 Other skin changes
0.666 0.334 0.000
I44.7 Left bundle-branch block, unspecified
0.666 0.334 0.000
G40.8 Other epilepsy
0.665 0.335 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.665 0.335 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.665 0.335 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.665 0.335 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.665 0.335 0.000
F10.3 Withdrawal state
0.664 0.336 0.000
Q21 Congenital malformations of cardiac septa
0.664 0.336 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.663 0.336 0.000
S32.5 Fracture of pubis
0.663 0.337 0.000
Chapter I Certain infectious and parasitic diseases
0.663 0.337 0.000
L50-L54 Urticaria and erythema
0.662 0.338 0.000
N73 Other female pelvic inflammatory diseases
0.661 0.339 0.000
I42.0 Dilated cardiomyopathy
0.661 0.339 0.000
Y44 Agents primarily affecting blood constituents
0.661 0.339 0.000
R46 Symptoms and signs involving appearance and behaviour
0.661 0.339 0.000
R43 Disturbances of smell and taste
0.661 0.339 0.000
U80 Agent resistant to penicillin and related antibiotics
0.661 0.339 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.660 0.339 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.660 0.339 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.660 0.339 0.000
G45.0 Vertebro-basilar artery syndrome
0.660 0.339 0.000
G03 Meningitis due to other and unspecified causes
0.660 0.339 0.000
V99 Unspecified transport accident
0.660 0.340 0.000
L57.0 Actinic keratosis
0.660 0.340 0.000
I31.3 Pericardial effusion (noninflammatory)
0.660 0.340 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.659 0.341 0.000
I60-I69 Cerebrovascular diseases
0.658 0.342 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.657 0.343 0.000
S51 Open wound of forearm
0.657 0.343 0.000
G35 Multiple sclerosis
0.656 0.344 0.000
N76 Other inflammation of vagina and vulva
0.656 0.344 0.000
I35.9 Aortic valve disorder, unspecified
0.656 0.344 0.000
G80 Infantile cerebral palsy
0.655 0.345 0.000
Q64 Other congenital malformations of urinary system
0.655 0.345 0.000
Q63 Other congenital malformations of kidney
0.655 0.345 0.000
Q62 Congenital obstructive defects of renal pelvis and congenital malformations of ureter
0.655 0.345 0.000
Q60 Renal agenesis and other reduction defects of kidney
0.655 0.345 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.654 0.346 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.653 0.347 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.653 0.347 0.000
L44 Other papulosquamous disorders
0.653 0.347 0.000
L41 Parapsoriasis
0.653 0.347 0.000
L45 Papulosquamous disorders in diseases classified elsewhere
0.653 0.347 0.000
L42 Pityriasis rosea
0.653 0.347 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.652 0.347 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.652 0.347 0.000
O85-O92 Complications predominantly related to the puerperium
0.652 0.348 0.000
G24 Dystonia
0.652 0.348 0.000
G23 Other degenerative diseases of basal ganglia
0.652 0.348 0.000
G21 Secondary Parkinsonism
0.652 0.348 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.652 0.348 0.000
G22 Parkinsonism in diseases classified elsewhere
0.652 0.348 0.000
V10-V19 Pedal cyclist injured in transport accident
0.651 0.348 0.000
S81.8 Open wound of other parts of lower leg
0.651 0.349 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.651 0.349 0.000
C56 Malignant neoplasm of ovary
0.651 0.349 0.000
N17 Acute renal failure
0.651 0.349 0.000
L27.0 Generalised skin eruption due to drugs and medicaments
0.650 0.350 0.000
S32.1 Fracture of sacrum
0.650 0.350 0.000
G93.3 Postviral fatigue syndrome
0.650 0.350 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.650 0.350 0.000
O72 Postpartum haemorrhage
0.649 0.351 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.649 0.351 0.000
R50-R69 General symptoms and signs
0.649 0.351 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.648 0.352 0.000
I21.9 Acute myocardial infarction, unspecified
0.647 0.353 0.000
C15.9 Oesophagus, unspecified
0.645 0.355 0.000
I21.4 Acute subendocardial myocardial infarction
0.645 0.355 0.000
N18.2 Chronic kidney disease, stage 2
0.645 0.355 0.000
Y85 Sequelae of transport accidents
0.644 0.356 0.000
L40.5 Arthropathic psoriasis
0.644 0.356 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.643 0.357 0.000
G90 Disorders of autonomic nervous system
0.643 0.357 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.643 0.357 0.000
G92 Toxic encephalopathy
0.643 0.357 0.000
R40 Somnolence, stupor and coma
0.642 0.358 0.000
I42.8 Other cardiomyopathies
0.642 0.358 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.642 0.358 0.000
S00.7 Multiple superficial injuries of head
0.641 0.359 0.000
S00.5 Superficial injury of lip and oral cavity
0.641 0.359 0.000
S00.4 Superficial injury of ear
0.641 0.359 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.641 0.359 0.000
C81 Hodgkin's disease
0.641 0.359 0.000
N26 Unspecified contracted kidney
0.641 0.359 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.641 0.359 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.641 0.359 0.000
R21 Rash and other nonspecific skin eruption
0.640 0.360 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.640 0.360 0.000
S82.0 Fracture of patella
0.639 0.361 0.000
X63 Intentional self-poisoning by and exposure to other drugs acting on the autonomic nervous system
0.638 0.362 0.000
O00 Ectopic pregnancy
0.638 0.362 0.000
Y59 Other and unspecified vaccines and biological substances
0.638 0.362 0.000
Y58 Bacterial vaccines
0.638 0.362 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.638 0.362 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.638 0.362 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.638 0.362 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.638 0.362 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.638 0.362 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.638 0.362 0.000
Y48 Anaesthetics and therapeutic gases
0.638 0.362 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.638 0.362 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.638 0.362 0.000
O80-O84 Delivery
0.637 0.363 0.000
S82.1 Fracture of upper end of tibia
0.636 0.364 0.000
T86.8 Failure and rejection of other transplanted organs and tissues
0.636 0.364 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.636 0.364 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.636 0.364 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.636 0.364 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.636 0.364 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.636 0.364 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.636 0.364 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.636 0.364 0.000
F11 Mental and behavioural disorders due to use of opioids
0.636 0.364 0.000
F10.2 Dependence syndrome
0.636 0.364 0.000
I35.0 Aortic (valve) stenosis
0.635 0.365 0.000
G47 Sleep disorders
0.635 0.365 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.634 0.366 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.634 0.366 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.634 0.366 0.000
T82.3 Mechanical complication of other vascular grafts
0.634 0.366 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.634 0.366 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.634 0.366 0.000
S80.0 Contusion of knee
0.634 0.366 0.000
N45 Orchitis and epididymitis
0.633 0.367 0.000
D00-D09 In situ neoplasms
0.633 0.367 0.000
O42.9 Premature rupture of membranes, unspecified
0.632 0.368 0.000
S01.0 Open wound of scalp
0.632 0.368 0.000
S01.8 Open wound of other parts of head
0.632 0.368 0.000
C25 Malignant neoplasm of pancreas
0.632 0.368 0.000
S32.3 Fracture of ilium
0.632 0.368 0.000
I86 Varicose veins of other sites
0.631 0.369 0.000
R73 Elevated blood glucose level
0.631 0.369 0.000
L29 Pruritus
0.630 0.370 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.630 0.370 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.629 0.370 0.000
S37 Injury of urinary and pelvic organs
0.629 0.370 0.000
S36 Injury of intra-abdominal organs
0.629 0.370 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.629 0.370 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.629 0.370 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.629 0.370 0.000
S31 Open wound of abdomen, lower back and pelvis
0.629 0.370 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.629 0.370 0.000
W00-W19 Falls
0.629 0.370 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.629 0.371 0.000
N04 Nephrotic syndrome
0.629 0.371 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.629 0.371 0.000
N07 Hereditary nephropathy, not elsewhere classified
0.627 0.372 0.000
N06 Isolated proteinuria with specified morphological lesion
0.627 0.372 0.000
N01 Rapidly progressive nephritic syndrome
0.627 0.372 0.000
N00 Acute nephritic syndrome
0.627 0.372 0.000
L40.0 Psoriasis vulgaris
0.627 0.373 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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