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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1291621
log Bayes Factor = 15.6995
Chromosome 12   position 46,340,821  (GRCh37) Explore rs1291621 on Ensembl!
Variant rs1291621 is part of Cluster X0126

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
I20-I25 Ischaemic heart diseases
0.998 0.002 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.995 0.005 0.000
Chapter VI Diseases of the nervous system
0.994 0.006 0.000
Chapter VII Diseases of the eye and adnexa
0.992 0.008 0.000
I25 Chronic ischaemic heart disease
0.988 0.012 0.000
S00-S09 Injuries to the head
0.988 0.012 0.000
F30-F39 Mood [affective] disorders
0.982 0.018 0.000
M50-M54 Other dorsopathies
0.973 0.027 0.000
S01 Open wound of head
0.973 0.027 0.000
M20-M25 Other joint disorders
0.972 0.028 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.971 0.029 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.970 0.030 0.000
T81 Complications of procedures, not elsewhere classified
0.967 0.033 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.967 0.033 0.000
I30-I52 Other forms of heart disease
0.964 0.036 0.000
S80-S89 Injuries to the knee and lower leg
0.962 0.038 0.000
F17.1 Harmful use
0.958 0.042 0.000
Chapter XX External causes of morbidity and mortality
0.954 0.046 0.000
I25.1 Atherosclerotic heart disease
0.954 0.046 0.000
F10.1 Harmful use
0.951 0.049 0.000
F31 Bipolar affective disorder
0.950 0.050 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.948 0.052 0.000
M54 Dorsalgia
0.938 0.062 0.000
S82 Fracture of lower leg, including ankle
0.936 0.064 0.000
S70-S79 Injuries to the hip and thigh
0.936 0.064 0.000
H25-H28 Disorders of lens
0.934 0.066 0.000
G20-G26 Extrapyramidal and movement disorders
0.930 0.070 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.927 0.073 0.000
M45-M49 Spondylopathies
0.925 0.075 0.000
Chapter XIV Diseases of the genitourinary system
0.919 0.081 0.000
T81.4 Infection following a procedure, not elsewhere classified
0.919 0.081 0.000
H30-H36 Disorders of choroid and retina
0.917 0.083 0.000
M80-M85 Disorders of bone density and structure
0.916 0.084 0.000
I20 Angina pectoris
0.914 0.086 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.909 0.091 0.000
I21 Acute myocardial infarction
0.909 0.091 0.000
M65-M68 Disorders of synovium and tendon
0.908 0.092 0.000
I46 Cardiac arrest
0.906 0.094 0.000
I25.2 Old myocardial infarction
0.903 0.097 0.000
I44 Atrioventricular and left bundle-branch block
0.902 0.098 0.000
O60-O75 Complications of labour and delivery
0.900 0.100 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.898 0.102 0.000
M05-M14 Inflammatory polyarthropathies
0.893 0.107 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.890 0.110 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.884 0.116 0.000
G20 Parkinson's disease
0.882 0.118 0.000
M47 Spondylosis
0.881 0.119 0.000
S82.3 Fracture of lower end of tibia
0.881 0.119 0.000
S90-S99 Injuries to the ankle and foot
0.877 0.123 0.000
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified
0.873 0.127 0.000
F31.9 Bipolar affective disorder, unspecified
0.870 0.130 0.000
G90-G99 Other disorders of the nervous system
0.870 0.130 0.000
N60-N64 Disorders of breast
0.870 0.130 0.000
I42 Cardiomyopathy
0.869 0.131 0.000
H35 Other retinal disorders
0.868 0.132 0.000
G70-G73 Diseases of myoneural junction and muscle
0.868 0.132 0.000
M24 Other specific joint derangements
0.867 0.133 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.865 0.135 0.000
S10-S19 Injuries to the neck
0.864 0.136 0.000
S01.0 Open wound of scalp
0.863 0.137 0.000
S01.9 Open wound of head, part unspecified
0.862 0.138 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.862 0.138 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.861 0.139 0.000
S06 Intracranial injury
0.861 0.139 0.000
M06 Other rheumatoid arthritis
0.858 0.142 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.857 0.143 0.000
S01.8 Open wound of other parts of head
0.856 0.144 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.853 0.147 0.000
M65 Synovitis and tenosynovitis
0.852 0.148 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.846 0.154 0.000
M20 Acquired deformities of fingers and toes
0.845 0.155 0.000
M40-M43 Deforming dorsopathies
0.845 0.155 0.000
M47.9 Spondylosis, unspecified
0.844 0.156 0.000
H25 Senile cataract
0.841 0.159 0.000
S82.30 Fracture of lower end of tibia (closed)
0.841 0.159 0.000
I20.0 Unstable angina
0.839 0.161 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.839 0.161 0.000
M54.9 Dorsalgia, unspecified
0.837 0.163 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.834 0.166 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.834 0.166 0.000
X60-X84 Intentional self-harm
0.833 0.167 0.000
M81 Osteoporosis without pathological fracture
0.832 0.168 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.832 0.168 0.000
O70 Perineal laceration during delivery
0.832 0.168 0.000
I44.2 Atrioventricular block, complete
0.829 0.171 0.000
I46.9 Cardiac arrest, unspecified
0.826 0.174 0.000
M23 Internal derangement of knee
0.826 0.174 0.000
Chapter XXII Codes for special purposes
0.825 0.175 0.000
I21.9 Acute myocardial infarction, unspecified
0.824 0.176 0.000
F29 Unspecified nonorganic psychosis
0.823 0.177 0.000
O48 Prolonged pregnancy
0.822 0.178 0.000
M06.9 Rheumatoid arthritis, unspecified
0.822 0.178 0.000
S02 Fracture of skull and facial bones
0.815 0.185 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.814 0.186 0.000
F33 Recurrent depressive disorder
0.813 0.187 0.000
S82.8 Fractures of other parts of lower leg
0.810 0.190 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.810 0.190 0.000
S79 Other and unspecified injuries of hip and thigh
0.809 0.191 0.000
S01.4 Open wound of cheek and temporomandibular area
0.807 0.193 0.000
S01.7 Multiple open wounds of head
0.807 0.193 0.000
S72 Fracture of femur
0.806 0.194 0.000
H55-H59 Other disorders of eye and adnexa
0.806 0.194 0.000
T87 Complications peculiar to reattachment and amputation
0.806 0.194 0.000
F22 Persistent delusional disorders
0.805 0.195 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.804 0.196 0.000
I22 Subsequent myocardial infarction
0.803 0.197 0.000
N99-N99 Other disorders of the genitourinary system
0.802 0.198 0.000
H35.8 Other specified retinal disorders
0.802 0.198 0.000
F32 Depressive episode
0.801 0.199 0.000
F10.3 Withdrawal state
0.800 0.200 0.000
M54.5 Low back pain
0.799 0.201 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.797 0.203 0.000
M51 Other intervertebral disk disorders
0.796 0.204 0.000
H26 Other cataract
0.795 0.205 0.000
H43-H45 Disorders of vitreous body and globe
0.795 0.205 0.000
I25.4 Coronary artery aneurysm
0.792 0.208 0.000
O70.0 First degree perineal laceration during delivery
0.787 0.213 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.785 0.215 0.000
N61 Inflammatory disorders of breast
0.785 0.215 0.000
V10-V19 Pedal cyclist injured in transport accident
0.784 0.216 0.000
G40-G47 Episodic and paroxysmal disorders
0.784 0.216 0.000
F10.9 Unspecified mental and behavioural disorder
0.781 0.219 0.000
I47 Paroxysmal tachycardia
0.779 0.221 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.778 0.222 0.000
H53-H54 Visual disturbances and blindness
0.777 0.223 0.000
T40.2 Other opioids
0.776 0.224 0.000
T81.3 Disruption of operation wound, not elsewhere classified
0.776 0.224 0.000
M81.9 Osteoporosis, unspecified
0.775 0.225 0.000
I46.0 Cardiac arrest with successful resuscitation
0.774 0.226 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.774 0.226 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.769 0.231 0.000
M25 Other joint disorders, not elsewhere classified
0.769 0.231 0.000
I36 Nonrheumatic tricuspid valve disorders
0.768 0.232 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.767 0.233 0.000
T88.4 Failed or difficult intubation
0.767 0.233 0.000
S80 Superficial injury of lower leg
0.766 0.234 0.000
M23.3 Other meniscus derangements
0.765 0.235 0.000
H25.1 Senile nuclear cataract
0.765 0.235 0.000
M34 Systemic sclerosis
0.765 0.235 0.000
M53 Other dorsopathies, not elsewhere classified
0.763 0.237 0.000
N72 Inflammatory disease of cervix uteri
0.763 0.237 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.762 0.238 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.761 0.239 0.000
N70 Salpingitis and oophoritis
0.761 0.239 0.000
S90 Superficial injury of ankle and foot
0.761 0.239 0.000
M54.6 Pain in thoracic spine
0.760 0.240 0.000
S20-S29 Injuries to the thorax
0.760 0.240 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.758 0.242 0.000
M86-M90 Other osteopathies
0.757 0.243 0.000
M54.1 Radiculopathy
0.756 0.244 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.756 0.244 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.756 0.244 0.000
O64 Obstructed labour due to malposition and malpresentation of foetus
0.756 0.244 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.755 0.245 0.000
I95 Hypotension
0.755 0.245 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.754 0.246 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.754 0.246 0.000
M43 Other deforming dorsopathies
0.752 0.247 0.000
N64 Other disorders of breast
0.752 0.248 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.752 0.248 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.749 0.251 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.749 0.251 0.000
F20 Schizophrenia
0.747 0.253 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.747 0.253 0.000
M47.92 Spondylosis, unspecified (Cervical region)
0.747 0.253 0.000
S40-S49 Injuries to the shoulder and upper arm
0.745 0.255 0.000
F23 Acute and transient psychotic disorders
0.745 0.255 0.000
W00-W19 Falls
0.744 0.256 0.000
M24.1 Other articular cartilage disorders
0.744 0.256 0.000
F41 Other anxiety disorders
0.741 0.259 0.000
M54.4 Lumbago with sciatica
0.740 0.260 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.739 0.261 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.738 0.262 0.000
M47.99 Spondylosis, unspecified (Site unspecified)
0.738 0.262 0.000
S70 Superficial injury of hip and thigh
0.738 0.262 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.737 0.263 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.737 0.263 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.736 0.264 0.000
H10-H13 Disorders of conjunctiva
0.735 0.265 0.000
N80 Endometriosis
0.735 0.265 0.000
S06.5 Traumatic subdural haemorrhage
0.732 0.268 0.000
I25.3 Aneurysm of heart
0.732 0.268 0.000
I44.0 Atrioventricular block, first degree
0.732 0.268 0.000
I49 Other cardiac arrhythmias
0.732 0.268 0.000
I20.9 Angina pectoris, unspecified
0.731 0.269 0.000
G24 Dystonia
0.731 0.269 0.000
H18 Other disorders of cornea
0.730 0.270 0.000
T81.9 Unspecified complication of procedure
0.730 0.270 0.000
Chapter X Diseases of the respiratory system
0.729 0.271 0.000
S72.0 Fracture of neck of femur
0.729 0.271 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.728 0.272 0.000
F80-F89 Disorders of psychological development
0.728 0.272 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.727 0.273 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.727 0.273 0.000
G30-G32 Other degenerative diseases of the nervous system
0.726 0.273 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.725 0.275 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.725 0.275 0.000
M21 Other acquired deformities of limbs
0.724 0.276 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.724 0.276 0.000
G82 Paraplegia and tetraplegia
0.723 0.276 0.000
S82.1 Fracture of upper end of tibia
0.723 0.277 0.000
I95.1 Orthostatic hypotension
0.723 0.277 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.721 0.279 0.000
S01.3 Open wound of ear
0.719 0.281 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.719 0.281 0.000
N99 Postprocedural disorders of genito-urinary system, not elsewhere classified
0.719 0.281 0.000
S79.9 Unspecified injury of hip and thigh
0.718 0.282 0.000
H33 Retinal detachments and breaks
0.718 0.282 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.717 0.283 0.000
F70-F79 Mental retardation
0.717 0.283 0.000
F60-F69 Disorders of adult personality and behaviour
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
W20-W49 Exposure to inanimate mechanical forces
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.284 0.000
I23 Certain current complications following acute myocardial infarction
0.715 0.285 0.000
G70 Myasthenia gravis and other myoneural disorders
0.715 0.285 0.000
F99-F99 Unspecified mental disorder
0.715 0.285 0.000
T66-T78 Other and unspecified effects of external causes
0.715 0.285 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.715 0.285 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.715 0.285 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.715 0.285 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.715 0.285 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.715 0.285 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.715 0.285 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.715 0.285 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.715 0.285 0.000
F11 Mental and behavioural disorders due to use of opioids
0.715 0.285 0.000
H25.0 Senile incipient cataract
0.714 0.286 0.000
H27 Other disorders of lens
0.713 0.287 0.000
O00-O08 Pregnancy with abortive outcome
0.713 0.287 0.000
M20.2 Hallux rigidus
0.713 0.287 0.000
S82.4 Fracture of fibula alone
0.712 0.288 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.712 0.288 0.000
M20.5 Other deformities of toe(s) (acquired)
0.712 0.288 0.000
G93 Other disorders of brain
0.710 0.290 0.000
T88.5 Other complications of anaesthesia
0.710 0.290 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.710 0.290 0.000
M82 Osteoporosis in diseases classified elsewhere
0.709 0.291 0.000
I25.6 Silent myocardial ischaemia
0.708 0.292 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.708 0.292 0.000
S08 Traumatic amputation of part of head
0.708 0.292 0.000
S07 Crushing injury of head
0.708 0.292 0.000
S05 Injury of eye and orbit
0.708 0.292 0.000
S04 Injury of cranial nerves
0.708 0.292 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.708 0.292 0.000
S82.2 Fracture of shaft of tibia
0.708 0.292 0.000
S12 Fracture of neck
0.708 0.292 0.000
M65.3 Trigger finger
0.706 0.294 0.000
O71 Other obstetric trauma
0.706 0.294 0.000
O73 Retained placenta and membranes, without haemorrhage
0.706 0.294 0.000
T81.8 Other complications of procedures, not elsewhere classified
0.706 0.294 0.000
M85 Other disorders of bone density and structure
0.705 0.294 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.705 0.295 0.000
F38 Other mood [affective] disorders
0.704 0.296 0.000
F34 Persistent mood [affective] disorders
0.704 0.296 0.000
F30 Manic episode
0.704 0.296 0.000
F39 Unspecified mood [affective] disorder
0.704 0.296 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.704 0.296 0.000
H35.3 Degeneration of macula and posterior pole
0.704 0.296 0.000
F22.0 Delusional disorder
0.703 0.297 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.703 0.297 0.000
N94.6 Dysmenorrhoea, unspecified
0.702 0.298 0.000
F10.4 Withdrawal state with delirium
0.702 0.298 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.701 0.299 0.000
H16 Keratitis
0.701 0.299 0.000
N00-N08 Glomerular diseases
0.701 0.299 0.000
T86 Failure and rejection of transplanted organs and tissues
0.701 0.299 0.000
N73 Other female pelvic inflammatory diseases
0.699 0.301 0.000
N87 Dysplasia of cervix uteri
0.699 0.301 0.000
S82.0 Fracture of patella
0.698 0.301 0.000
I44.7 Left bundle-branch block, unspecified
0.698 0.302 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.698 0.302 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.698 0.302 0.000
S81 Open wound of lower leg
0.697 0.303 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.697 0.303 0.000
M33 Dermatopolymyositis
0.697 0.303 0.000
M32 Systemic lupus erythematosus
0.697 0.303 0.000
M30 Polyarteritis nodosa and related conditions
0.697 0.303 0.000
T88.8 Other specified complications of surgical and medical care, not elsewhere classified
0.697 0.303 0.000
F10.8 Other mental and behavioural disorders
0.696 0.303 0.000
F10.7 Residual and late-onset psychotic disorder
0.696 0.303 0.000
F10.6 Amnesic syndrome
0.696 0.303 0.000
F10.5 Psychotic disorder
0.696 0.303 0.000
F17.9 Unspecified mental and behavioural disorder
0.696 0.304 0.000
F17.8 Other mental and behavioural disorders
0.696 0.304 0.000
F17.7 Residual and late-onset psychotic disorder
0.696 0.304 0.000
F17.6 Amnesic syndrome
0.696 0.304 0.000
F17.5 Psychotic disorder
0.696 0.304 0.000
F17.4 Withdrawal state with delirium
0.696 0.304 0.000
F17.3 Withdrawal state
0.696 0.304 0.000
F17.0 Acute intoxication
0.696 0.304 0.000
I42.0 Dilated cardiomyopathy
0.695 0.305 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.695 0.305 0.000
G71 Primary disorders of muscles
0.694 0.306 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.694 0.306 0.000
S01.2 Open wound of nose
0.694 0.306 0.000
F41.2 Mixed anxiety and depressive disorder
0.693 0.307 0.000
T81.7 Vascular complications following a procedure, not elsewhere classified
0.693 0.307 0.000
T81.6 Acute reaction to foreign substance accidentally left during a procedure
0.693 0.307 0.000
T81.1 Shock during or resulting from a procedure, not elsewhere classified
0.693 0.307 0.000
O85-O92 Complications predominantly related to the puerperium
0.693 0.307 0.000
I30 Acute pericarditis
0.692 0.308 0.000
S02.2 Fracture of nasal bones
0.692 0.308 0.000
H35.7 Separation of retinal layers
0.692 0.308 0.000
O62 Abnormalities of forces of labour
0.691 0.309 0.000
I52 Other heart disorders in diseases classified elsewhere
0.691 0.309 0.000
I48 Atrial fibrillation and flutter
0.691 0.309 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.691 0.309 0.000
I41 Myocarditis in diseases classified elsewhere
0.691 0.309 0.000
I40 Acute myocarditis
0.691 0.309 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.691 0.309 0.000
I37 Pulmonary valve disorders
0.691 0.309 0.000
I32 Pericarditis in diseases classified elsewhere
0.691 0.309 0.000
S88 Traumatic amputation of lower leg
0.690 0.310 0.000
S87 Crushing injury of lower leg
0.690 0.310 0.000
S86 Injury of muscle and tendon at lower leg level
0.690 0.310 0.000
S85 Injury of blood vessels at lower leg level
0.690 0.310 0.000
S84 Injury of nerves at lower leg level
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
S01.5 Open wound of lip and oral cavity
0.689 0.310 0.000
T79-T79 Certain early complications of trauma
0.689 0.311 0.000
I70 Atherosclerosis
0.688 0.311 0.000
N62 Hypertrophy of breast
0.688 0.312 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.688 0.312 0.000
M24.0 Loose body in joint
0.688 0.312 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.687 0.313 0.000
G95 Other diseases of spinal cord
0.687 0.313 0.000
M43.1 Spondylolisthesis
0.686 0.314 0.000
N83.1 Corpus luteum cyst
0.685 0.315 0.000
I20.8 Other forms of angina pectoris
0.685 0.315 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.684 0.316 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.684 0.316 0.000
Y35-Y36 Legal intervention and operations of war
0.684 0.316 0.000
Y10-Y34 Event of undetermined intent
0.684 0.316 0.000
Y00-Y09 Assault
0.684 0.316 0.000
X85-X99 Assault
0.684 0.316 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.684 0.316 0.000
X30-X39 Exposure to forces of nature
0.684 0.316 0.000
X20-X29 Contact with venomous animals and plants
0.684 0.316 0.000
X10-X19 Contact with heat and hot substances
0.684 0.316 0.000
X00-X09 Exposure to smoke, fire and flames
0.684 0.316 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.684 0.316 0.000
W75-W84 Other accidental threats to breathing
0.684 0.316 0.000
W65-W74 Accidental drowning and submersion
0.684 0.316 0.000
W50-W64 Exposure to animate mechanical forces
0.684 0.316 0.000
V98-V99 Other and unspecified transport accidents
0.684 0.316 0.000
V95-V97 Air and space transport accidents
0.684 0.316 0.000
V90-V94 Water transport accidents
0.684 0.316 0.000
V70-V79 Bus occupant injured in transport accident
0.684 0.316 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.684 0.316 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.684 0.316 0.000
V40-V49 Car occupant injured in transport accident
0.684 0.316 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.684 0.316 0.000
V01-V09 Pedestrian injured in transport accident
0.684 0.316 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.684 0.316 0.000
I47.2 Ventricular tachycardia
0.682 0.318 0.000
F31.8 Other bipolar affective disorders
0.681 0.319 0.000
F31.7 Bipolar affective disorder, currently in remission
0.681 0.319 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.681 0.319 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.681 0.319 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.681 0.319 0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression
0.681 0.319 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.679 0.320 0.000
F25 Schizoaffective disorders
0.679 0.321 0.000
F28 Other nonorganic psychotic disorders
0.679 0.321 0.000
F24 Induced delusional disorder
0.679 0.321 0.000
F21 Schizotypal disorder
0.679 0.321 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.679 0.321 0.000
N70.1 Chronic salpingitis and oophoritis
0.679 0.321 0.000
M22 Disorders of patella
0.679 0.321 0.000
N60 Benign mammary dysplasia
0.678 0.322 0.000
H26.0 Infantile, juvenile and presenile cataract
0.678 0.322 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.678 0.322 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.677 0.323 0.000
S89 Other and unspecified injuries of lower leg
0.676 0.324 0.000
M24.2 Disorder of ligament
0.676 0.324 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.676 0.324 0.000
S10 Superficial injury of neck
0.675 0.325 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.673 0.326 0.000
I49.0 Ventricular fibrillation and flutter
0.673 0.327 0.000
S72.00 Fracture of neck of femur (closed)
0.673 0.327 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.673 0.327 0.000
M54.8 Other dorsalgia
0.673 0.327 0.000
M54.0 Panniculitis affecting regions of neck and back
0.673 0.327 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.672 0.328 0.000
O44 Placenta praevia
0.672 0.328 0.000
I24 Other acute ischaemic heart diseases
0.671 0.329 0.000
S82.9 Fracture of lower leg, part unspecified
0.671 0.329 0.000
S82.7 Multiple fractures of lower leg
0.671 0.329 0.000
S82.5 Fracture of medial malleolus
0.671 0.329 0.000
S78 Traumatic amputation of hip and thigh
0.671 0.329 0.000
S77 Crushing injury of hip and thigh
0.671 0.329 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.671 0.329 0.000
S75 Injury of blood vessels at hip and thigh level
0.671 0.329 0.000
S74 Injury of nerves at hip and thigh level
0.671 0.329 0.000
S73 Dislocation, sprain and strain of joint and ligaments of hip
0.671 0.329 0.000
S71 Open wound of hip and thigh
0.671 0.329 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.670 0.330 0.000
T87.6 Other and unspecified complications of amputation stump
0.670 0.330 0.000
G80 Infantile cerebral palsy
0.669 0.331 0.000
G83 Other paralytic syndromes
0.669 0.331 0.000
S06.8 Other intracranial injuries
0.669 0.331 0.000
M50 Cervical disk disorders
0.669 0.331 0.000
S92 Fracture of foot, except ankle
0.668 0.332 0.000
M47.2 Other spondylosis with radiculopathy
0.668 0.332 0.000
M47.96 Spondylosis, unspecified (Lumbar region)
0.668 0.332 0.000
G23 Other degenerative diseases of basal ganglia
0.666 0.333 0.000
G21 Secondary Parkinsonism
0.666 0.333 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.666 0.333 0.000
G22 Parkinsonism in diseases classified elsewhere
0.666 0.333 0.000
S19 Other and unspecified injuries of neck
0.666 0.334 0.000
F32.9 Depressive episode, unspecified
0.666 0.334 0.000
S30.9 Superficial injury of abdomen, lower back and pelvis, part unspecified
0.666 0.334 0.000
H35.5 Hereditary retinal dystrophy
0.666 0.334 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.665 0.335 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.665 0.335 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.665 0.335 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.665 0.335 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.665 0.335 0.000
T36 Poisoning by systemic antibiotics
0.665 0.335 0.000
O66 Other obstructed labour
0.665 0.335 0.000
M49 Spondylopathies in diseases classified elsewhere
0.663 0.337 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.663 0.337 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.663 0.337 0.000
G72 Other myopathies
0.662 0.338 0.000
S06.0 Concussion
0.662 0.338 0.000
N99.8 Other postprocedural disorders of genito-urinary system
0.661 0.339 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.661 0.339 0.000
S32 Fracture of lumbar spine and pelvis
0.661 0.339 0.000
M48 Other spondylopathies
0.661 0.339 0.000
H33.0 Retinal detachment with retinal break
0.661 0.339 0.000
M06.3 Rheumatoid nodule
0.661 0.339 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.661 0.339 0.000
J30-J39 Other diseases of upper respiratory tract
0.660 0.340 0.000
S90.8 Other superficial injuries of ankle and foot
0.660 0.340 0.000
I31 Other diseases of pericardium
0.659 0.340 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.659 0.341 0.000
S39.9 Unspecified injury of abdomen, lower back and pelvis
0.658 0.341 0.000
S60-S69 Injuries to the wrist and hand
0.658 0.342 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.658 0.342 0.000
H31 Other disorders of choroid
0.658 0.342 0.000
H30 Chorioretinal inflammation
0.658 0.342 0.000
M31 Other necrotising vasculopathies
0.657 0.342 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.657 0.343 0.000
I77 Other disorders of arteries and arterioles
0.657 0.343 0.000
M83 Adult osteomalacia
0.656 0.343 0.000
S00 Superficial injury of head
0.656 0.344 0.000
V20-V29 Motorcycle rider injured in transport accident
0.656 0.344 0.000
T82.1 Mechanical complication of cardiac electronic device
0.655 0.345 0.000
I74 Arterial embolism and thrombosis
0.655 0.345 0.000
O72 Postpartum haemorrhage
0.655 0.345 0.000
X62.9 Unspecified place
0.654 0.346 0.000
M47.1 Other spondylosis with myelopathy
0.653 0.347 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.652 0.348 0.000
S99 Other and unspecified injuries of ankle and foot
0.652 0.348 0.000
Chapter VIII Diseases of the ear and mastoid process
0.652 0.348 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.652 0.348 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.652 0.348 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.652 0.348 0.000
M54.56 Low back pain (Lumbar region)
0.651 0.349 0.000
G47 Sleep disorders
0.651 0.349 0.000
M24.15 Other articular cartilage disorders (Pelvic region and thigh)
0.651 0.349 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.651 0.349 0.000
M66 Spontaneous rupture of synovium and tendon
0.651 0.349 0.000
J33 Nasal polyp
0.651 0.349 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.650 0.350 0.000
M20.3 Other deformity of hallux (acquired)
0.650 0.350 0.000
I46.1 Sudden cardiac death, so described
0.650 0.350 0.000
H35.6 Retinal haemorrhage
0.649 0.351 0.000
M84 Disorders of continuity of bone
0.648 0.352 0.000
M47.97 Spondylosis, unspecified (Lumbosacral region)
0.648 0.352 0.000
N76 Other inflammation of vagina and vulva
0.648 0.352 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.648 0.352 0.000
I44.6 Other and unspecified fascicular block
0.647 0.353 0.000
I44.5 Left posterior fascicular block
0.647 0.353 0.000
I44.4 Left anterior fascicular block
0.647 0.353 0.000
I44.3 Other and unspecified atrioventricular block
0.647 0.353 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.647 0.353 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.646 0.354 0.000
M06.0 Seronegative rheumatoid arthritis
0.646 0.354 0.000
O74 Complications of anaesthesia during labour and delivery
0.645 0.354 0.000
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified
0.645 0.354 0.000
O65 Obstructed labour due to maternal pelvic abnormality
0.645 0.354 0.000
O61 Failed induction of labour
0.645 0.354 0.000
O60 Preterm delivery
0.645 0.354 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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