TreeWAS – Variant ID: rs12997492

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter XXI Factors influencing health status and contact with health services	1.000	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	1.000	0.000
# Top node	1.000	0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	1.000	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	1.000	0.000
Z92 Personal history of medical treatment	0.998	0.002
Chapter X Diseases of the respiratory system	0.997	0.003
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.996	0.004
Z70-Z76 Persons encountering health services in other circumstances	0.994	0.006
Z92.1 Personal history of long-term (current) use of anticoagulants	0.988	0.012
Z72 Problems related to lifestyle	0.987	0.013
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.985	0.015
Z72.0 Tobacco use	0.985	0.015
Z92.3 Personal history of irradiation	0.980	0.020
Z85 Personal history of malignant neoplasm	0.976	0.024
Chapter XX External causes of morbidity and mortality	0.976	0.024
S00-S09 Injuries to the head	0.972	0.028
T84.0 Mechanical complication of internal joint prosthesis	0.971	0.029
M05-M14 Inflammatory polyarthropathies	0.971	0.029
T81 Complications of procedures, not elsewhere classified	0.971	0.029
S60-S69 Injuries to the wrist and hand	0.970	0.030
Z96 Presence of other functional implants	0.970	0.030
Chapter II Neoplasms	0.964	0.036
M06 Other rheumatoid arthritis	0.960	0.040
S80-S89 Injuries to the knee and lower leg	0.956	0.044
Z96.6 Presence of orthopaedic joint implants	0.956	0.044
Z80 Family history of malignant neoplasm	0.953	0.047
C15-C26 Malignant neoplasms of digestive organs	0.950	0.050
M06.9 Rheumatoid arthritis, unspecified	0.948	0.052
J09-J18 Influenza and pneumonia	0.946	0.054
Z93 Artificial opening status	0.942	0.058
S66 Injury of muscle and tendon at wrist and hand level	0.941	0.059
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.935	0.065
T81.3 Disruption of operation wound, not elsewhere classified	0.934	0.066
S00 Superficial injury of head	0.930	0.070
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues	0.925	0.075
C25 Malignant neoplasm of pancreas	0.921	0.079
Z85.5 Personal history of malignant neoplasm of urinary tract	0.917	0.083
S01 Open wound of head	0.913	0.087
Z85.4 Personal history of malignant neoplasm of genital organs	0.901	0.099
T66-T78 Other and unspecified effects of external causes	0.900	0.100
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.899	0.101
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.898	0.102
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.898	0.102
C20 Malignant neoplasm of rectum	0.897	0.103
J95-J99 Other diseases of the respiratory system	0.894	0.106
Z95 Presence of cardiac and vascular implants and grafts	0.894	0.106
Z40-Z54 Persons encountering health services for specific procedures and health care	0.894	0.106
J18 Pneumonia, organism unspecified	0.893	0.107
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.892	0.108
C64-C68 Malignant neoplasms of urinary tract	0.890	0.110
M06.94 Rheumatoid arthritis, unspecified (Hand)	0.887	0.113
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts	0.884	0.116
Z80.4 Family history of malignant neoplasm of genital organs	0.882	0.118
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.880	0.120
J18.1 Lobar pneumonia, unspecified	0.877	0.123
T81.0 Haemorrhage and haematoma complicating a procedure, not elsewhere classified	0.877	0.123
Z95.2 Presence of prosthetic heart valve	0.874	0.126
M40-M43 Deforming dorsopathies	0.870	0.130
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.867	0.133
J30-J39 Other diseases of upper respiratory tract	0.861	0.139
J00-J06 Acute upper respiratory infections	0.860	0.140
Z93.6 Other artificial openings of urinary tract status	0.860	0.140
D37-D48 Neoplasms of uncertain or unknown behaviour	0.857	0.143
Z96.7 Presence of other bone and tendon implants	0.850	0.150
Z93.2 Ileostomy status	0.849	0.151
C25.0 Head of pancreas	0.849	0.151
S00.0 Superficial injury of scalp	0.847	0.153
C25.9 Pancreas, unspecified	0.847	0.153
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs	0.846	0.154
J80-J84 Other respiratory diseases principally affecting the interstitium	0.846	0.154
S40-S49 Injuries to the shoulder and upper arm	0.845	0.155
S80 Superficial injury of lower leg	0.843	0.157
D60-D64 Aplastic and other anaemias	0.840	0.160
Z92.4 Personal history of major surgery, not elsewhere classified	0.839	0.161
T81.4 Infection following a procedure, not elsewhere classified	0.834	0.166
Z80.3 Family history of malignant neoplasm of breast	0.834	0.166
Z43 Attention to artificial openings	0.833	0.167
T84.2 Mechanical complication of internal fixation device of other bones	0.831	0.169
T78 Adverse effects, not elsewhere classified	0.829	0.171
Z97 Presence of other devices	0.826	0.174
Chapter XV Pregnancy, childbirth and the puerperium	0.825	0.175
Z60 Problems related to social environment	0.824	0.176
Y85 Sequelae of transport accidents	0.824	0.176
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.823	0.177
C67 Malignant neoplasm of bladder	0.820	0.180
M80-M85 Disorders of bone density and structure	0.820	0.180
M65-M68 Disorders of synovium and tendon	0.819	0.181
S82 Fracture of lower leg, including ankle	0.816	0.184
Z49 Care involving dialysis	0.815	0.185
Z88.5 Personal history of allergy to narcotic agent	0.815	0.185
Z73 Problems related to life-management difficulty	0.814	0.186
S10-S19 Injuries to the neck	0.812	0.187
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.812	0.188
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.810	0.190
M07 Psoriatic and enteropathic arthropathies	0.808	0.192
J40-J47 Chronic lower respiratory diseases	0.808	0.192
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]	0.807	0.193
D00-D09 In situ neoplasms	0.804	0.196
S66.8 Injury of other muscles and tendons at wrist and hand level	0.803	0.197
M41 Scoliosis	0.795	0.205
Z74 Problems related to care-provider dependency	0.790	0.210
S70-S79 Injuries to the hip and thigh	0.790	0.210
S01.3 Open wound of ear	0.790	0.210
J60-J70 Lung diseases due to external agents	0.789	0.211
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.788	0.212
S66.2 Injury of extensor muscle and tendon of thumb at wrist and hand level	0.786	0.214
C21 Malignant neoplasm of anus and anal canal	0.784	0.215
Z43.2 Attention to ileostomy	0.782	0.218
S64 Injury of nerves at wrist and hand level	0.781	0.219
Z89 Acquired absence of limb	0.779	0.221
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.779	0.221
S66.7 Injury of multiple extensor muscles and tendons at wrist and hand level	0.778	0.222
T85 Complications of other internal prosthetic devices, implants and grafts	0.777	0.223
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.777	0.223
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.774	0.226
T79-T79 Certain early complications of trauma	0.774	0.226
S01.9 Open wound of head, part unspecified	0.774	0.226
S67 Crushing injury of wrist and hand	0.773	0.227
J38 Diseases of vocal cords and larynx, not elsewhere classified	0.773	0.227
Z88.6 Personal history of allergy to analgesic agent	0.771	0.229
T84.5 Infection and inflammatory reaction due to internal joint prosthesis	0.771	0.229
W20-W49 Exposure to inanimate mechanical forces	0.771	0.229
Z88.7 Personal history of allergy to serum and vaccine	0.769	0.231
S66.6 Injury of multiple flexor muscles and tendons at wrist and hand level	0.768	0.232
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts	0.768	0.232
Z53 Persons encountering health services for specifie procedures, not carried out	0.768	0.232
T20-T25 Burns and corrosions of external body surface, specified by site	0.766	0.234
S00.9 Superficial injury of head, part unspecified	0.766	0.234
S81 Open wound of lower leg	0.764	0.236
M06.0 Seronegative rheumatoid arthritis	0.760	0.240
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.760	0.240
S05 Injury of eye and orbit	0.759	0.240
V80-V89 Other land transport accidents	0.759	0.241
S50-S59 Injuries to the elbow and forearm	0.758	0.242
T80 Complications following infusion, transfusion and therapeutic injection	0.757	0.243
S01.0 Open wound of scalp	0.757	0.243
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.756	0.243
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.753	0.247
Z88.2 Personal history of allergy to sulphonamides	0.753	0.247
Z57 Occupational exposure to risk-factors	0.752	0.248
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.751	0.249
Y85.0 Sequelae of motor-vehicle accident	0.750	0.250
Z08 Follow-up examination after treatment for malignant neoplasm	0.749	0.251
Z80.9 Family history of malignant neoplasm, unspecified	0.748	0.252
J99 Respiratory disorders in diseases classified elsewhere	0.748	0.252
Z00-Z13 Persons encountering health services for examination and investigation	0.747	0.253
D64 Other anaemias	0.747	0.253
Z80.1 Family history of malignant neoplasm of trachea, bronchus and lung	0.746	0.254
T78.4 Allergy, unspecified	0.745	0.255
Z60.2 Living alone	0.745	0.255
J00 Acute nasopharyngitis [common cold]	0.743	0.257
V40-V49 Car occupant injured in transport accident	0.742	0.258
M41.9 Scoliosis, unspecified	0.741	0.259
S20-S29 Injuries to the thorax	0.740	0.260
S00.2 Other superficial injuries of eyelid and periocular area	0.739	0.261
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.738	0.262
T92 Sequelae of injuries of upper limb	0.738	0.262
J04 Acute laryngitis and tracheitis	0.737	0.263
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level	0.736	0.264
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.734	0.266
V20-V29 Motorcycle rider injured in transport accident	0.733	0.267
J13 Pneumonia due to Streptococcus pneumoniae	0.732	0.268
W00-W19 Falls	0.732	0.268
D63 Anaemia in chronic diseases classified elsewhere	0.731	0.269
Z63 Other problems related to primary support group, including family circumstances	0.731	0.269
Z80.7 Family history of malignant neoplasms of lymphoid, haematopoietic and related tissues	0.731	0.269
Z58 Problems related to physical environment	0.728	0.272
M05 Seropositive rheumatoid arthritis	0.727	0.273
S82.3 Fracture of lower end of tibia	0.726	0.274
Z08.9 Follow-up examination after unspecified treatment for malignant neoplasm	0.726	0.274
J34 Other disorders of nose and nasal sinuses	0.724	0.276
J98 Other respiratory disorders	0.723	0.277
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level	0.723	0.277
T84.1 Mechanical complication of internal fixation device of bones of limb	0.722	0.278
Z95.4 Presence of other heart-valve replacement	0.722	0.278
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level	0.720	0.280
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.720	0.280
S01.5 Open wound of lip and oral cavity	0.720	0.280
Z42 Follow-up care involving plastic surgery	0.720	0.280
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.719	0.281
S00.7 Multiple superficial injuries of head	0.718	0.282
Q60-Q64 Congenital malformations of the urinary system	0.718	0.282
T33-T35 Frostbite	0.717	0.283
T26-T28 Burns and corrosions confined to eye and internal organs	0.717	0.283
T00-T07 Injuries involving multiple body regions	0.717	0.283
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283
Z84 Family history of other conditions	0.717	0.283
Z81 Family history of mental and behavioural disorders	0.717	0.283
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.717	0.283
T87 Complications peculiar to reattachment and amputation	0.717	0.283
T91 Sequelae of injuries of neck and trunk	0.715	0.284
Z92.9 Personal history of medical treatment, unspecified	0.715	0.284
Z92.5 Personal history of rehabilitation measures	0.715	0.284
S00.3 Superficial injury of nose	0.715	0.285
J20-J22 Other acute lower respiratory infections	0.715	0.285
T93 Sequelae of injuries of lower limb	0.715	0.285
T84.9 Unspecified complication of internal orthopaedic prosthetic device, implant and graft	0.714	0.286
T84.3 Mechanical complication of other bone devices, implants and grafts	0.714	0.286
Z76 Persons encountering health services in other circumstances	0.713	0.287
Z70 Counselling related to sexual attitude, behaviour and orientation	0.713	0.287
D80-D89 Certain disorders involving the immune mechanism	0.712	0.288
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.711	0.289
Z92.8 Personal history of other medical treatment	0.711	0.289
S62 Fracture at wrist and hand level	0.711	0.289
M91-M94 Chondropathies	0.710	0.290
T81.9 Unspecified complication of procedure	0.710	0.290
D45 Polycythaemia vera	0.710	0.290
S80.9 Superficial injury of lower leg, unspecified	0.710	0.290
X60-X84 Intentional self-harm	0.709	0.291
M00-M03 Infectious arthropathies	0.709	0.291
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.708	0.292
Z72.2 Drug use	0.708	0.292
Z72.9 Problem related to lifestyle, unspecified	0.708	0.292
Z72.8 Other problems related to lifestyle	0.708	0.292
Z72.6 Gambling and betting	0.708	0.292
Z72.5 High-risk sexual behaviour	0.708	0.292
Z72.4 Inappropriate diet and eating habits	0.708	0.292
Z72.3 Lack of physical exercise	0.708	0.292
M60-M63 Disorders of muscles	0.706	0.294
J95 Postprocedural respiratory disorders, not elsewhere classified	0.706	0.294
J10 Influenza due to identified influenza virus	0.706	0.294
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts	0.706	0.294
T86 Failure and rejection of transplanted organs and tissues	0.705	0.295
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.705	0.295
X40-X49 Accidental poisoning by and exposure to noxious substances	0.704	0.296
M67 Other disorders of synovium and tendon	0.704	0.296
C92 Myeloid leukaemia	0.703	0.297
T94 Sequelae of injuries involving multiple and unspecified body regions	0.702	0.298
J81 Pulmonary oedema	0.701	0.299
S00.8 Superficial injury of other parts of head	0.701	0.299
Z97.8 Presence of other specified devices	0.700	0.300
O80-O84 Delivery	0.700	0.300
Z85.0 Personal history of malignant neoplasm of digestive organs	0.700	0.300
Z85.9 Personal history of malignant neoplasm, unspecified	0.700	0.300
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.700	0.300
Y35-Y36 Legal intervention and operations of war	0.700	0.300
Y10-Y34 Event of undetermined intent	0.700	0.300
Y00-Y09 Assault	0.700	0.300
X85-X99 Assault	0.700	0.300
X58-X59 Accidental exposure to other and unspecified factors	0.700	0.300
X50-X57 Overexertion, travel and privation	0.700	0.300
X30-X39 Exposure to forces of nature	0.700	0.300
X20-X29 Contact with venomous animals and plants	0.700	0.300
X10-X19 Contact with heat and hot substances	0.700	0.300
X00-X09 Exposure to smoke, fire and flames	0.700	0.300
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.700	0.300
W75-W84 Other accidental threats to breathing	0.700	0.300
W65-W74 Accidental drowning and submersion	0.700	0.300
W50-W64 Exposure to animate mechanical forces	0.700	0.300
V98-V99 Other and unspecified transport accidents	0.700	0.300
V95-V97 Air and space transport accidents	0.700	0.300
V90-V94 Water transport accidents	0.700	0.300
V70-V79 Bus occupant injured in transport accident	0.700	0.300
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.700	0.300
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.700	0.300
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.700	0.300
V01-V09 Pedestrian injured in transport accident	0.700	0.300
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.700	0.300
Z93.0 Tracheostomy status	0.699	0.301
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.699	0.301
J47 Bronchiectasis	0.699	0.301
J80 Adult respiratory distress syndrome	0.699	0.301
J34.8 Other specified disorders of nose and nasal sinuses	0.699	0.301
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.698	0.302
Z93.1 Gastrostomy status	0.698	0.302
Y85.9 Sequelae of other and unspecified transport accidents	0.698	0.302
Z95.3 Presence of xenogenic heart valve	0.698	0.302
C64 Malignant neoplasm of kidney, except renal pelvis	0.698	0.302
Z80.5 Family history of malignant neoplasm of urinary tract	0.697	0.302
S08 Traumatic amputation of part of head	0.697	0.303
S07 Crushing injury of head	0.697	0.303
S04 Injury of cranial nerves	0.697	0.303
S03 Dislocation, sprain and strain of joints and ligaments of head	0.697	0.303
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.696	0.303
M14 Arthropathies in other diseases classified elsewhere	0.696	0.304
M12 Other specific arthropathies	0.696	0.304
M09 Juvenile arthritis in diseases classified elsewhere	0.696	0.304
M08 Juvenile arthritis	0.696	0.304
T81.7 Vascular complications following a procedure, not elsewhere classified	0.696	0.304
T81.6 Acute reaction to foreign substance accidentally left during a procedure	0.696	0.304
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure	0.696	0.304
T81.1 Shock during or resulting from a procedure, not elsewhere classified	0.696	0.304
S69 Other and unspecified injuries of wrist and hand	0.695	0.305
S65 Injury of blood vessels at wrist and hand level	0.695	0.305
Z96.9 Presence of functional implant, unspecified	0.695	0.305
Z96.5 Presence of tooth-root and mandibular implants	0.695	0.305
Z96.4 Presence of endocrine implants	0.695	0.305
Z96.3 Presence of artificial larynx	0.695	0.305
Z96.2 Presence of otological and audiological implants	0.695	0.305
C82 Follicular [nodular] non-Hodgkin's lymphoma	0.694	0.306
J11 Influenza, virus not identified	0.692	0.308
Z49.1 Extracorporeal dialysis	0.692	0.308
M07.3 Other psoriatic arthropathies	0.692	0.308
T36-T50 Poisoning by drugs, medicaments and biological substances	0.692	0.308
C40-C41 Malignant neoplasms of bone and articular cartilage	0.691	0.309
C67.9 Bladder, unspecified	0.690	0.310
M50-M54 Other dorsopathies	0.690	0.310
S80.0 Contusion of knee	0.689	0.311
Z93.4 Other artificial openings of gastro-intestinal tract status	0.688	0.312
M06.8 Other specified rheumatoid arthritis	0.688	0.312
M06.4 Inflammatory polyarthropathy	0.688	0.312
M06.3 Rheumatoid nodule	0.688	0.312
M06.2 Rheumatoid bursitis	0.688	0.312
M06.1 Adult-onset Still's disease	0.688	0.312
Chapter XXII Codes for special purposes	0.688	0.312
Y60-Y69 Misadventures to patients during surgical and medical care	0.687	0.313
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.687	0.313
J32 Chronic sinusitis	0.686	0.314
Z53.0 Procedure not carried out because of contraindication	0.686	0.314
S89 Other and unspecified injuries of lower leg	0.686	0.314
S88 Traumatic amputation of lower leg	0.686	0.314
S87 Crushing injury of lower leg	0.686	0.314
S86 Injury of muscle and tendon at lower leg level	0.686	0.314
S85 Injury of blood vessels at lower leg level	0.686	0.314
S84 Injury of nerves at lower leg level	0.686	0.314
Z73.9 Problem related to life-management difficulty, unspecified	0.685	0.315
Q80-Q89 Other congenital malformations	0.685	0.315
M86-M90 Other osteopathies	0.683	0.317
Z80.8 Family history of malignant neoplasm of other organs or systems	0.683	0.317
Z80.6 Family history of leukaemia	0.683	0.317
Z80.2 Family history of malignant neoplasm of other respiratory and intrathoracic organs	0.683	0.317
S90-S99 Injuries to the ankle and foot	0.682	0.318
C26 Malignant neoplasm of other and ill-defined digestive organs	0.681	0.319
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.681	0.319
C17 Malignant neoplasm of small intestine	0.681	0.319
C23 Malignant neoplasm of gallbladder	0.681	0.319
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.681	0.319
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.681	0.319
T15-T19 Effects of foreign body entering through natural orifice	0.680	0.320
M06.98 Rheumatoid arthritis, unspecified (Other)	0.680	0.320
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)	0.680	0.320
M06.93 Rheumatoid arthritis, unspecified (Forearm)	0.680	0.320
M06.92 Rheumatoid arthritis, unspecified (Upper arm)	0.680	0.320
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)	0.680	0.320
Z92.0 Personal history of contraception	0.680	0.320
D64.9 Anaemia, unspecified	0.680	0.320
J17 Pneumonia in diseases classified elsewhere	0.678	0.322
J16 Pneumonia due to other infectious organisms, not elsewhere classified	0.678	0.322
J15 Bacterial pneumonia, not elsewhere classified	0.678	0.322
J12 Viral pneumonia, not elsewhere classified	0.678	0.322
J14 Pneumonia due to Haemophilus influenzae	0.678	0.322
J09 Influenza due to certain identified influenza virus	0.678	0.322
M10 Gout	0.678	0.322
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.677	0.323
Z52 Donors of organs and tissues	0.676	0.323
Z53.9 Procedure not carried out, unspecified reason	0.677	0.323
S66.1 Injury of flexor muscle and tendon of other finger at wrist and hand level	0.676	0.324
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.676	0.324
Z93.9 Artificial opening status, unspecified	0.675	0.325
Z93.8 Other artificial opening status	0.675	0.325
S66.9 Injury of unspecified muscle and tendon at wrist and hand level	0.675	0.325
S66.5 Injury of intrinsic muscle and tendon of other finger at wrist and hand level	0.675	0.325
S66.4 Injury of intrinsic muscle and tendon of thumb at wrist and hand level	0.675	0.325
S40 Superficial injury of shoulder and upper arm	0.674	0.326
Z88.4 Personal history of allergy to anaesthetic agent	0.673	0.327
S01.4 Open wound of cheek and temporomandibular area	0.673	0.327
V10-V19 Pedal cyclist injured in transport accident	0.673	0.327
S06 Intracranial injury	0.671	0.329
Z65 Problems related to other psychosocial circumstances	0.670	0.329
Z64 Problems related to certain psychosocial circumstances	0.670	0.329
Z62 Other problems related to upbringing	0.670	0.329
Z61 Problems related to negative life events in childhood	0.670	0.329
Z59 Problems related to housing and economic circumstances	0.670	0.329
Z56 Problems related to employment and unemployment	0.670	0.329
Z55 Problems related to education and literacy	0.670	0.329
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.670	0.330
Z96.8 Presence of other specified functional implants	0.669	0.331
C67.6 Ureteric orifice	0.669	0.331
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts	0.669	0.331
S82.2 Fracture of shaft of tibia	0.668	0.332
M70-M79 Other soft tissue disorders	0.668	0.332
S00.5 Superficial injury of lip and oral cavity	0.667	0.333
S00.4 Superficial injury of ear	0.667	0.333
Z08.2 Follow-up examination after chemotherapy for malignant neoplasm	0.666	0.334
O20-O29 Other maternal disorders predominantly related to pregnancy	0.663	0.337
Z49.0 Preparatory care for dialysis	0.663	0.337
T78.0 Anaphylactic shock due to adverse food reaction	0.663	0.337
J43 Emphysema	0.662	0.338
S82.30 Fracture of lower end of tibia (closed)	0.662	0.338
M81 Osteoporosis without pathological fracture	0.661	0.339
C25.8 Overlapping lesion of pancreas	0.661	0.339
C25.7 Other parts of pancreas	0.661	0.339
C25.4 Endocrine pancreas	0.661	0.339
C25.3 Pancreatic duct	0.661	0.339
C25.2 Tail of pancreas	0.661	0.339
C25.1 Body of pancreas	0.661	0.339
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances	0.659	0.341
J61 Pneumoconiosis due to asbestos and other mineral fibres	0.658	0.342
D61 Other aplastic anaemias	0.657	0.342
Z41 Procedures for purposes other than remedying health state	0.657	0.343
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.657	0.343
S46 Injury of muscle and tendon at shoulder and upper arm level	0.656	0.343
Z95.5 Presence of coronary angioplasty implant and graft	0.656	0.344
M41.99 Scoliosis, unspecified (Site unspecified)	0.655	0.345
J98.1 Pulmonary collapse	0.655	0.345
S01.7 Multiple open wounds of head	0.655	0.345
T78.2 Anaphylactic shock, unspecified	0.654	0.346
Z08.8 Follow-up examination after other treatment for malignant neoplasm	0.654	0.346
M11 Other crystal arthropathies	0.653	0.347
Chapter XI Diseases of the digestive system	0.653	0.347
D07 Carcinoma in situ of other and unspecified genital organs	0.653	0.347
Z49.2 Other dialysis	0.652	0.348
S82.0 Fracture of patella	0.650	0.350
J30 Vasomotor and allergic rhinitis	0.649	0.351
J04.0 Acute laryngitis	0.649	0.351
Y88 Sequelae of surgical and medical care as external cause	0.649	0.351
Z54 Convalescence	0.648	0.352
M84 Disorders of continuity of bone	0.647	0.353
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.646	0.354
T75 Effects of other external causes	0.646	0.354
T74 Maltreatment syndromes	0.646	0.354
T73 Effects of other deprivation	0.646	0.354
T70 Effects of air pressure and water pressure	0.646	0.354
T69 Other effects of reduced temperature	0.646	0.354
T67 Effects of heat and light	0.646	0.354
T71 Asphyxiation	0.646	0.354
T68 Hypothermia	0.646	0.354
T66 Unspecified effects of radiation	0.646	0.354
T88 Other complications of surgical and medical care, not elsewhere classified	0.645	0.354
Z42.1 Follow-up care involving plastic surgery of breast	0.645	0.355
D03 Melanoma in situ	0.644	0.356
D55-D59 Haemolytic anaemias	0.644	0.356
Z43.6 Attention to other artificial openings of urinary tract	0.644	0.356
T98 Sequelae of other and unspecified effects of external causes	0.644	0.356
T95 Sequelae of burns, corrosions and frostbite	0.644	0.356
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source	0.644	0.356
T96 Sequelae of poisoning by drugs, medicaments and biological substances	0.644	0.356
Z08.0 Follow-up examination after surgery for malignant neoplasm	0.644	0.356
Z74.0 Reduced mobility	0.644	0.356
Z97.0 Presence of artificial eye	0.643	0.356
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.643	0.357
J99.8 Respiratory disorders in other diseases classified elsewhere	0.643	0.357
Z95.8 Presence of other cardiac and vascular implants and grafts	0.642	0.358
S14 Injury of nerves and spinal cord at neck level	0.641	0.358
S61 Open wound of wrist and hand	0.642	0.358
J96 Respiratory failure, not elsewhere classified	0.641	0.359
C67.2 Lateral wall of bladder	0.641	0.359
Z44 Fitting and adjustment of external prosthetic device	0.641	0.359
Z71.2 Person consulting for explanation of investigation findings	0.640	0.359
J18.8 Other pneumonia, organism unspecified	0.640	0.360
J18.2 Hypostatic pneumonia, unspecified	0.640	0.360
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.640	0.360
J01 Acute sinusitis	0.639	0.361
Z83 Family history of other specific disorders	0.639	0.361
T83.0 Mechanical complication of urinary (indwelling) catheter	0.639	0.361
S60 Superficial injury of wrist and hand	0.639	0.361
C67.5 Bladder neck	0.639	0.361
C68 Malignant neoplasm of other and unspecified urinary organs	0.638	0.362
C66 Malignant neoplasm of ureter	0.638	0.362
C65 Malignant neoplasm of renal pelvis	0.638	0.362
J42 Unspecified chronic bronchitis	0.637	0.363
S01.8 Open wound of other parts of head	0.637	0.363
S72 Fracture of femur	0.637	0.363
C19 Malignant neoplasm of rectosigmoid junction	0.636	0.363
Chapter VII Diseases of the eye and adnexa	0.636	0.364
T31 Burns classified according to extent of body surface involved	0.636	0.364
Y44 Agents primarily affecting blood constituents	0.636	0.364
S51 Open wound of forearm	0.636	0.364
J38.1 Polyp of vocal cord and larynx	0.634	0.366
Q50-Q56 Congenital malformations of genital organs	0.634	0.366
Z48 Other surgical follow-up care	0.634	0.366
C16 Malignant neoplasm of stomach	0.634	0.366
Y51 Drugs primarily affecting the autonomic nervous system	0.633	0.367
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.633	0.367
S01.1 Open wound of eyelid and periocular area	0.632	0.368
S64.2 Injury of radial nerve at wrist and hand level	0.632	0.368
S67.0 Crushing injury of thumb and other finger(s)	0.632	0.368
Q38-Q45 Other congenital malformations of the digestive system	0.632	0.368
C85 Other and unspecified types of non-Hodgkin's lymphoma	0.631	0.368
Y89 Sequelae of other external causes	0.631	0.369
Y87 Sequelae of intentional self-harm, assault and events of undetermined intent	0.631	0.369
C71 Malignant neoplasm of brain	0.631	0.369
Z85.6 Personal history of leukaemia	0.631	0.369
D63.0 Anaemia in neoplastic disease	0.630	0.370
S80.1 Contusion of other and unspecified parts of lower leg	0.629	0.371
C21.0 Anus, unspecified	0.628	0.371
S68 Traumatic amputation of wrist and hand	0.627	0.373
M45-M49 Spondylopathies	0.626	0.374
S83.6 Sprain and strain of other and unspecified parts of knee	0.625	0.375
S81.9 Open wound of lower leg, part unspecified	0.624	0.376
M42 Spinal osteochondrosis	0.623	0.376
M40 Kyphosis and lordosis	0.623	0.376
C09 Malignant neoplasm of tonsil	0.623	0.377
C18 Malignant neoplasm of colon	0.623	0.377
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.622	0.378
Q35-Q37 Cleft lip and cleft palate	0.622	0.378
Q30-Q34 Congenital malformations of the respiratory system	0.622	0.378
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.622	0.378
M67.8 Other specified disorders of synovium and tendon	0.621	0.379
T83.8 Other complications of genito-urinary prosthetic devices, implants and grafts	0.621	0.379
M41.90 Scoliosis, unspecified (Multiple sites in spine)	0.621	0.379
Q20-Q28 Congenital malformations of the circulatory system	0.621	0.379
S50 Superficial injury of forearm	0.620	0.380
J39 Other diseases of upper respiratory tract	0.620	0.380
O13 Gestational [pregnancy-induced] hypertension without significant proteinuria	0.620	0.380
M13 Other arthritis	0.620	0.380
S10 Superficial injury of neck	0.619	0.380
Z89.4 Acquired absence of foot and ankle	0.619	0.381
M80 Osteoporosis with pathological fracture	0.618	0.382

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations