TreeWAS – Variant ID: rs1318498

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability	Protective posterior probability
Chapter IX Diseases of the circulatory system	1.000	0.000	0.000
# Top node	1.000	0.000	0.000
Chapter V Mental and behavioural disorders	0.998	0.002	0.000
Chapter VI Diseases of the nervous system	0.997	0.003	0.000
I70-I79 Diseases of arteries, arterioles and capillaries	0.996	0.004	0.000
Chapter II Neoplasms	0.994	0.006	0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.993	0.007	0.000
Chapter XIV Diseases of the genitourinary system	0.989	0.011	0.000
T36-T50 Poisoning by drugs, medicaments and biological substances	0.984	0.016	0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.982	0.018	0.000
N17-N19 Renal failure	0.982	0.018	0.000
I95-I99 Other and unspecified disorders of the circulatory system	0.980	0.020	0.000
I73 Other peripheral vascular diseases	0.978	0.022	0.000
N18 Chronic renal failure	0.976	0.024	0.000
I20-I25 Ischaemic heart diseases	0.968	0.032	0.000
G90-G99 Other disorders of the nervous system	0.968	0.032	0.000
I73.9 Peripheral vascular disease, unspecified	0.968	0.032	0.000
Chapter VII Diseases of the eye and adnexa	0.967	0.033	0.000
G40-G47 Episodic and paroxysmal disorders	0.966	0.034	0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.965	0.035	0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.961	0.039	0.000
I95 Hypotension	0.958	0.042	0.000
N60-N64 Disorders of breast	0.958	0.042	0.000
D37-D48 Neoplasms of uncertain or unknown behaviour	0.956	0.044	0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue	0.955	0.045	0.000
H40-H42 Glaucoma	0.948	0.052	0.000
F30-F39 Mood [affective] disorders	0.939	0.061	0.000
F20 Schizophrenia	0.935	0.065	0.000
H40 Glaucoma	0.934	0.066	0.000
Chapter XV Pregnancy, childbirth and the puerperium	0.934	0.066	0.000
I20 Angina pectoris	0.933	0.067	0.000
I95.1 Orthostatic hypotension	0.932	0.068	0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified	0.930	0.070	0.000
I77 Other disorders of arteries and arterioles	0.927	0.073	0.000
D69 Purpura and other haemorrhagic conditions	0.924	0.076	0.000
C43-C44 Melanoma and other malignant neoplasms of skin	0.922	0.078	0.000
H40.9 Glaucoma, unspecified	0.921	0.079	0.000
G43 Migraine	0.919	0.081	0.000
N18.0 End-stage renal disease	0.919	0.081	0.000
N60 Benign mammary dysplasia	0.914	0.086	0.000
N18.9 Chronic renal failure, unspecified	0.912	0.088	0.000
I20.0 Unstable angina	0.910	0.090	0.000
D69.6 Thrombocytopenia, unspecified	0.902	0.098	0.000
C44 Other malignant neoplasms of skin	0.900	0.100	0.000
I60-I69 Cerebrovascular diseases	0.899	0.101	0.000
D00-D09 In situ neoplasms	0.899	0.101	0.000
I30-I52 Other forms of heart disease	0.898	0.102	0.000
I24 Other acute ischaemic heart diseases	0.898	0.102	0.000
F20.9 Schizophrenia, unspecified	0.893	0.107	0.000
F00-F09 Organic, including symptomatic, mental disorders	0.892	0.108	0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.892	0.108	0.000
F31 Bipolar affective disorder	0.887	0.113	0.000
G43.9 Migraine, unspecified	0.886	0.114	0.000
D45 Polycythaemia vera	0.886	0.114	0.000
H53-H54 Visual disturbances and blindness	0.885	0.115	0.000
C51-C58 Malignant neoplasms of female genital organs	0.883	0.117	0.000
C15-C26 Malignant neoplasms of digestive organs	0.882	0.118	0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.874	0.126	0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.870	0.130	0.000
N00-N08 Glomerular diseases	0.869	0.131	0.000
G93 Other disorders of brain	0.869	0.131	0.000
I50 Heart failure	0.866	0.134	0.000
N60.1 Diffuse cystic mastopathy	0.862	0.138	0.000
M05-M14 Inflammatory polyarthropathies	0.861	0.139	0.000
G40 Epilepsy	0.860	0.140	0.000
Z72.1 Alcohol use	0.858	0.142	0.000
N10-N16 Renal tubulo-interstitial diseases	0.857	0.143	0.000
G99 Other disorders of nervous system in diseases classified elsewhere	0.855	0.145	0.000
Chapter XXI Factors influencing health status and contact with health services	0.852	0.148	0.000
Z70-Z76 Persons encountering health services in other circumstances	0.851	0.149	0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs	0.851	0.149	0.000
Z72 Problems related to lifestyle	0.850	0.150	0.000
N62 Hypertrophy of breast	0.850	0.150	0.000
N19 Unspecified renal failure	0.849	0.151	0.000
C44.2 Skin of ear and external auricular canal	0.849	0.151	0.000
N18.3 Chronic kidney disease, stage 3	0.846	0.154	0.000
D68 Other coagulation defects	0.846	0.154	0.000
G80-G83 Cerebral palsy and other paralytic syndromes	0.846	0.154	0.000
I77.1 Stricture of artery	0.844	0.156	0.000
Chapter XX External causes of morbidity and mortality	0.843	0.157	0.000
Chapter X Diseases of the respiratory system	0.843	0.157	0.000
I24.8 Other forms of acute ischaemic heart disease	0.839	0.161	0.000
M65-M68 Disorders of synovium and tendon	0.838	0.162	0.000
D50-D53 Nutritional anaemias	0.834	0.166	0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]	0.834	0.166	0.000
M06 Other rheumatoid arthritis	0.831	0.169	0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.830	0.170	0.000
N18.5 Chronic kidney disease, stage 5	0.827	0.173	0.000
H53 Visual disturbances	0.825	0.175	0.000
O00-O08 Pregnancy with abortive outcome	0.824	0.176	0.000
I27 Other pulmonary heart diseases	0.824	0.176	0.000
T43.2 Other and unspecified antidepressants	0.821	0.179	0.000
C19 Malignant neoplasm of rectosigmoid junction	0.820	0.180	0.000
G91 Hydrocephalus	0.819	0.181	0.000
H55-H59 Other disorders of eye and adnexa	0.819	0.181	0.000
F60-F69 Disorders of adult personality and behaviour	0.817	0.183	0.000
C56 Malignant neoplasm of ovary	0.815	0.185	0.000
O20-O29 Other maternal disorders predominantly related to pregnancy	0.812	0.188	0.000
I99 Other and unspecified disorders of circulatory system	0.812	0.188	0.000
I95.9 Hypotension, unspecified	0.811	0.189	0.000
M45-M49 Spondylopathies	0.809	0.191	0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics	0.808	0.192	0.000
M50-M54 Other dorsopathies	0.808	0.192	0.000
I69 Sequelae of cerebrovascular disease	0.806	0.194	0.000
G40.9 Epilepsy, unspecified	0.806	0.194	0.000
M06.9 Rheumatoid arthritis, unspecified	0.806	0.194	0.000
I70 Atherosclerosis	0.804	0.196	0.000
O60-O75 Complications of labour and delivery	0.801	0.199	0.000
I50.9 Heart failure, unspecified	0.801	0.199	0.000
N61 Inflammatory disorders of breast	0.801	0.199	0.000
F31.9 Bipolar affective disorder, unspecified	0.799	0.201	0.000
F20.0 Paranoid schizophrenia	0.797	0.203	0.000
I63 Cerebral infarction	0.796	0.204	0.000
C44.6 Skin of upper limb, including shoulder	0.796	0.204	0.000
I50.1 Left ventricular failure	0.795	0.205	0.000
N60.4 Mammary duct ectasia	0.791	0.209	0.000
M80-M85 Disorders of bone density and structure	0.790	0.210	0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.787	0.213	0.000
T43.0 Tricyclic and tetracyclic antidepressants	0.786	0.214	0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system	0.785	0.215	0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere	0.784	0.216	0.000
N13 Obstructive and reflux uropathy	0.781	0.219	0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.781	0.219	0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.779	0.221	0.000
I27.2 Other secondary pulmonary hypertension	0.778	0.222	0.000
G47 Sleep disorders	0.778	0.222	0.000
J00-J06 Acute upper respiratory infections	0.776	0.224	0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue	0.774	0.226	0.000
D04 Carcinoma in situ of skin	0.774	0.226	0.000
G99.2 Myelopathy in diseases classified elsewhere	0.774	0.226	0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.772	0.228	0.000
S10-S19 Injuries to the neck	0.768	0.232	0.000
M70-M79 Other soft tissue disorders	0.767	0.233	0.000
I20.9 Angina pectoris, unspecified	0.767	0.233	0.000
C44.7 Skin of lower limb, including hip	0.766	0.233	0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances	0.764	0.236	0.000
Chapter IV Endocrine, nutritional and metabolic diseases	0.764	0.236	0.000
S40-S49 Injuries to the shoulder and upper arm	0.762	0.238	0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.757	0.243	0.000
N25-N29 Other disorders of kidney and ureter	0.755	0.245	0.000
N99-N99 Other disorders of the genitourinary system	0.754	0.246	0.000
F10 Mental and behavioural disorders due to use of alcohol	0.754	0.246	0.000
F03 Unspecified dementia	0.753	0.247	0.000
S70-S79 Injuries to the hip and thigh	0.753	0.247	0.000
G93.8 Other specified disorders of brain	0.753	0.247	0.000
D70-D77 Other diseases of blood and blood-forming organs	0.752	0.248	0.000
I78 Diseases of capillaries	0.751	0.249	0.000
I42 Cardiomyopathy	0.751	0.249	0.000
S00-S09 Injuries to the head	0.749	0.251	0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.747	0.253	0.000
Q60-Q64 Congenital malformations of the urinary system	0.747	0.253	0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.746	0.254	0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.746	0.254	0.000
I77.9 Disorder of arteries and arterioles, unspecified	0.746	0.254	0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system	0.743	0.257	0.000
I60 Subarachnoid haemorrhage	0.742	0.258	0.000
T79-T79 Certain early complications of trauma	0.742	0.258	0.000
Chapter XII Diseases of the skin and subcutaneous tissue	0.742	0.258	0.000
Chapter XXII Codes for special purposes	0.741	0.259	0.000
O94-O99 Other obstetric conditions, not elsewhere classified	0.741	0.259	0.000
C44.9 Malignant neoplasm of skin, unspecified	0.740	0.260	0.000
C15 Malignant neoplasm of oesophagus	0.738	0.262	0.000
G81 Hemiplegia	0.737	0.263	0.000
S80-S89 Injuries to the knee and lower leg	0.734	0.266	0.000
F01 Vascular dementia	0.734	0.266	0.000
I38 Endocarditis, valve unspecified	0.734	0.266	0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms	0.733	0.267	0.000
T42.4 Benzodiazepines	0.733	0.267	0.000
C44.4 Skin of scalp and neck	0.732	0.268	0.000
F33 Recurrent depressive disorder	0.732	0.268	0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.731	0.269	0.000
I45 Other conduction disorders	0.731	0.269	0.000
M65 Synovitis and tenosynovitis	0.730	0.270	0.000
F80-F89 Disorders of psychological development	0.729	0.271	0.000
N03 Chronic nephritic syndrome	0.727	0.273	0.000
D80-D89 Certain disorders involving the immune mechanism	0.727	0.273	0.000
T40.2 Other opioids	0.726	0.274	0.000
F22 Persistent delusional disorders	0.726	0.274	0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.725	0.275	0.000
G70-G73 Diseases of myoneural junction and muscle	0.725	0.275	0.000
F29 Unspecified nonorganic psychosis	0.723	0.277	0.000
G93.6 Cerebral oedema	0.723	0.277	0.000
I44 Atrioventricular and left bundle-branch block	0.722	0.278	0.000
H53.8 Other visual disturbances	0.721	0.279	0.000
T43.5 Other and unspecified antipsychotics and neuroleptics	0.721	0.279	0.000
J02 Acute pharyngitis	0.720	0.280	0.000
S50-S59 Injuries to the elbow and forearm	0.719	0.281	0.000
T93 Sequelae of injuries of lower limb	0.717	0.283	0.000
I00-I02 Acute rheumatic fever	0.717	0.283	0.000
Chapter XVI Certain conditions originating in the perinatal period	0.717	0.283	0.000
G95 Other diseases of spinal cord	0.716	0.283	0.000
H40.0 Glaucoma suspect	0.716	0.284	0.000
T43.3 Phenothiazine antipsychotics and neuroleptics	0.716	0.284	0.000
F99-F99 Unspecified mental disorder	0.716	0.284	0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.716	0.284	0.000
F70-F79 Mental retardation	0.716	0.284	0.000
D68.8 Other specified coagulation defects	0.715	0.285	0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.715	0.285	0.000
G00-G09 Inflammatory diseases of the central nervous system	0.715	0.285	0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)	0.715	0.285	0.000
I72 Other aneurysm	0.714	0.286	0.000
S90-S99 Injuries to the ankle and foot	0.714	0.286	0.000
I71 Aortic aneurysm and dissection	0.713	0.287	0.000
F31.0 Bipolar affective disorder, current episode hypomanic	0.713	0.287	0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.713	0.287	0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.713	0.287	0.000
C40-C41 Malignant neoplasms of bone and articular cartilage	0.713	0.287	0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.713	0.287	0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries	0.713	0.287	0.000
T33-T35 Frostbite	0.712	0.288	0.000
T26-T28 Burns and corrosions confined to eye and internal organs	0.712	0.288	0.000
T20-T25 Burns and corrosions of external body surface, specified by site	0.712	0.288	0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.712	0.288	0.000
T00-T07 Injuries involving multiple body regions	0.712	0.288	0.000
I36 Nonrheumatic tricuspid valve disorders	0.712	0.288	0.000
G91.9 Hydrocephalus, unspecified	0.712	0.288	0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified	0.710	0.290	0.000
T15-T19 Effects of foreign body entering through natural orifice	0.709	0.291	0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs	0.705	0.295	0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system	0.705	0.295	0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system	0.705	0.295	0.000
T46 Poisoning by agents primarily affecting the cardiovascular system	0.705	0.295	0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified	0.705	0.295	0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system	0.705	0.295	0.000
T41 Poisoning by anaesthetics and therapeutic gases	0.705	0.295	0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.705	0.295	0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics	0.705	0.295	0.000
T36 Poisoning by systemic antibiotics	0.705	0.295	0.000
O72 Postpartum haemorrhage	0.705	0.295	0.000
D46 Myelodysplastic syndromes	0.704	0.295	0.000
D55-D59 Haemolytic anaemias	0.704	0.296	0.000
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.703	0.297	0.000
T39.1 4-Aminophenol derivatives	0.703	0.297	0.000
D50 Iron deficiency anaemia	0.702	0.298	0.000
C53 Malignant neoplasm of cervix uteri	0.702	0.298	0.000
I73.8 Other specified peripheral vascular diseases	0.701	0.299	0.000
I73.1 Thromboangiitis obliterans [Buerger]	0.701	0.299	0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction	0.701	0.299	0.000
F10.1 Harmful use	0.700	0.300	0.000
I77.6 Arteritis, unspecified	0.700	0.300	0.000
N18.8 Other chronic renal failure	0.700	0.300	0.000
N18.2 Chronic kidney disease, stage 2	0.700	0.300	0.000
N18.1 Chronic kidney disease, stage 1	0.700	0.300	0.000
N08 Glomerular disorders in diseases classified elsewhere	0.699	0.301	0.000
M51 Other intervertebral disk disorders	0.699	0.301	0.000
G93.9 Disorder of brain, unspecified	0.697	0.303	0.000
D06 Carcinoma in situ of cervix uteri	0.697	0.303	0.000
H53.9 Visual disturbance, unspecified	0.696	0.304	0.000
D68.2 Hereditary deficiency of other clotting factors	0.695	0.305	0.000
X60-X84 Intentional self-harm	0.695	0.305	0.000
I23 Certain current complications following acute myocardial infarction	0.694	0.306	0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified	0.694	0.306	0.000
G96 Other disorders of central nervous system	0.694	0.306	0.000
G94 Other disorders of brain in diseases classified elsewhere	0.694	0.306	0.000
G90 Disorders of autonomic nervous system	0.694	0.306	0.000
G98 Other disorders of nervous system, not elsewhere classified	0.694	0.306	0.000
G92 Toxic encephalopathy	0.694	0.306	0.000
X58-X59 Accidental exposure to other and unspecified factors	0.694	0.306	0.000
H46-H48 Disorders of optic nerve and visual pathways	0.693	0.307	0.000
H10-H13 Disorders of conjunctiva	0.693	0.307	0.000
G46 Vascular syndromes of brain in cerebrovascular diseases	0.693	0.307	0.000
G41 Status epilepticus	0.693	0.307	0.000
F25 Schizoaffective disorders	0.692	0.308	0.000
F23 Acute and transient psychotic disorders	0.692	0.308	0.000
F28 Other nonorganic psychotic disorders	0.692	0.308	0.000
F24 Induced delusional disorder	0.692	0.308	0.000
F21 Schizotypal disorder	0.692	0.308	0.000
I98 Other disorders of circulatory system in diseases classified elsewhere	0.692	0.308	0.000
C44.0 Skin of lip	0.691	0.308	0.000
D03 Melanoma in situ	0.691	0.309	0.000
F17 Mental and behavioural disorders due to use of tobacco	0.691	0.309	0.000
H40.2 Primary angle-closure glaucoma	0.691	0.309	0.000
M86-M90 Other osteopathies	0.690	0.310	0.000
D67 Hereditary factor IX deficiency	0.689	0.311	0.000
D66 Hereditary factor VIII deficiency	0.689	0.311	0.000
D65 Disseminated intravascular coagulation [defibrination syndrome]	0.689	0.311	0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.688	0.311	0.000
Q00-Q07 Congenital malformations of the nervous system	0.688	0.312	0.000
C79 Secondary malignant neoplasm of other sites	0.688	0.312	0.000
F60 Specific personality disorders	0.688	0.312	0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)	0.687	0.313	0.000
I95.8 Other hypotension	0.687	0.313	0.000
I95.0 Idiopathic hypotension	0.687	0.313	0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.687	0.313	0.000
O02 Other abnormal products of conception	0.687	0.313	0.000
C16 Malignant neoplasm of stomach	0.686	0.314	0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.685	0.314	0.000
S20-S29 Injuries to the thorax	0.685	0.314	0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.685	0.315	0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.685	0.315	0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.685	0.315	0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.685	0.315	0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.685	0.315	0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.685	0.315	0.000
M91-M94 Chondropathies	0.685	0.315	0.000
M60-M63 Disorders of muscles	0.685	0.315	0.000
M00-M03 Infectious arthropathies	0.685	0.315	0.000
D52 Folate deficiency anaemia	0.684	0.316	0.000
I05-I09 Chronic rheumatic heart diseases	0.684	0.316	0.000
G30-G32 Other degenerative diseases of the nervous system	0.683	0.316	0.000
Z76 Persons encountering health services in other circumstances	0.683	0.316	0.000
N60.3 Fibrosclerosis of breast	0.683	0.317	0.000
T88 Other complications of surgical and medical care, not elsewhere classified	0.682	0.318	0.000
X40-X49 Accidental poisoning by and exposure to noxious substances	0.680	0.320	0.000
H40.1 Primary open-angle glaucoma	0.680	0.320	0.000
J02.9 Acute pharyngitis, unspecified	0.680	0.320	0.000
H42 Glaucoma in diseases classified elsewhere	0.679	0.320	0.000
F05 Delirium, not induced by alcohol and other psychoactive substances	0.679	0.321	0.000
N11 Chronic tubulo-interstitial nephritis	0.678	0.322	0.000
J90-J94 Other diseases of pleura	0.677	0.323	0.000
O26 Maternal care for other conditions predominantly related to pregnancy	0.677	0.323	0.000
H43-H45 Disorders of vitreous body and globe	0.675	0.324	0.000
M79 Other soft tissue disorders, not elsewhere classified	0.675	0.325	0.000
O70 Perineal laceration during delivery	0.674	0.326	0.000
F38 Other mood [affective] disorders	0.673	0.327	0.000
F34 Persistent mood [affective] disorders	0.673	0.327	0.000
F30 Manic episode	0.673	0.327	0.000
F39 Unspecified mood [affective] disorder	0.673	0.327	0.000
D50.8 Other iron deficiency anaemias	0.672	0.328	0.000
F20.8 Other schizophrenia	0.670	0.330	0.000
F20.6 Simple schizophrenia	0.670	0.330	0.000
F20.5 Residual schizophrenia	0.670	0.330	0.000
F20.4 Postschizophrenic depression	0.670	0.330	0.000
F20.3 Undifferentiated schizophrenia	0.670	0.330	0.000
F20.2 Catatonic schizophrenia	0.670	0.330	0.000
F20.1 Hebephrenic schizophrenia	0.670	0.330	0.000
H40.8 Other glaucoma	0.670	0.330	0.000
H40.6 Glaucoma secondary to drugs	0.670	0.330	0.000
H40.5 Glaucoma secondary to other eye disorders	0.670	0.330	0.000
H40.4 Glaucoma secondary to eye inflammation	0.670	0.330	0.000
H40.3 Glaucoma secondary to eye trauma	0.670	0.330	0.000
O85-O92 Complications predominantly related to the puerperium	0.670	0.330	0.000
G20-G26 Extrapyramidal and movement disorders	0.669	0.331	0.000
M65.9 Synovitis and tenosynovitis, unspecified	0.668	0.332	0.000
D07 Carcinoma in situ of other and unspecified genital organs	0.668	0.332	0.000
T43.9 Psychotropic drug, unspecified	0.667	0.333	0.000
T43.8 Other psychotropic drugs, not elsewhere classified	0.667	0.333	0.000
T43.6 Psychostimulants with abuse potential	0.667	0.333	0.000
T43.4 Butyrophenone and thioxanthene neuroleptics	0.667	0.333	0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants	0.667	0.333	0.000
I33 Acute and subacute endocarditis	0.666	0.334	0.000
I70.2 Atherosclerosis of arteries of the extremities	0.665	0.334	0.000
I77.8 Other specified disorders of arteries and arterioles	0.664	0.335	0.000
I77.5 Necrosis of artery	0.664	0.335	0.000
I77.4 Coeliac artery compression syndrome	0.664	0.335	0.000
I77.3 Arterial fibromuscular dysplasia	0.664	0.335	0.000
I77.2 Rupture of artery	0.664	0.335	0.000
I77.0 Arteriovenous fistula, acquired	0.664	0.335	0.000
O04 Medical abortion	0.664	0.336	0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)	0.663	0.337	0.000
I95.2 Hypotension due to drugs	0.663	0.337	0.000
D69.9 Haemorrhagic condition, unspecified	0.662	0.338	0.000
D69.8 Other specified haemorrhagic conditions	0.662	0.338	0.000
D69.5 Secondary thrombocytopenia	0.662	0.338	0.000
D69.4 Other primary thrombocytopenia	0.662	0.338	0.000
D69.2 Other nonthrombocytopenic purpura	0.662	0.338	0.000
D69.1 Qualitative platelet defects	0.662	0.338	0.000
D69.0 Allergic purpura	0.662	0.338	0.000
G35-G37 Demyelinating diseases of the central nervous system	0.661	0.339	0.000
D05 Carcinoma in situ of breast	0.661	0.339	0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.661	0.339	0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)	0.660	0.340	0.000
G81.9 Hemiplegia, unspecified	0.660	0.340	0.000
F32 Depressive episode	0.659	0.341	0.000
G43.8 Other migraine	0.659	0.341	0.000
G43.3 Complicated migraine	0.659	0.341	0.000
G43.2 Status migrainosus	0.659	0.341	0.000
G43.0 Migraine without aura [common migraine]	0.659	0.341	0.000
Q61 Cystic kidney disease	0.658	0.342	0.000
N13.3 Other and unspecified hydronephrosis	0.658	0.342	0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures	0.657	0.343	0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.657	0.343	0.000
N02 Recurrent and persistent haematuria	0.656	0.343	0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs	0.656	0.344	0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.656	0.344	0.000
M81 Osteoporosis without pathological fracture	0.655	0.345	0.000
N60.9 Benign mammary dysplasia, unspecified	0.655	0.345	0.000
T66-T78 Other and unspecified effects of external causes	0.654	0.345	0.000
M46 Other inflammatory spondylopathies	0.654	0.346	0.000
M67 Other disorders of synovium and tendon	0.654	0.346	0.000
S06 Intracranial injury	0.653	0.347	0.000
H57 Other disorders of eye and adnexa	0.652	0.348	0.000
O24 Diabetes mellitus in pregnancy	0.652	0.348	0.000
I21 Acute myocardial infarction	0.651	0.349	0.001
G50-G59 Nerve, nerve root and plexus disorders	0.651	0.349	0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow	0.650	0.350	0.000
H55 Nystagmus and other irregular eye movements	0.650	0.350	0.000
M50 Cervical disk disorders	0.649	0.351	0.000
G63 Polyneuropathy in diseases classified elsewhere	0.648	0.352	0.000
Q50-Q56 Congenital malformations of genital organs	0.648	0.352	0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified	0.648	0.352	0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction	0.647	0.353	0.000
I31 Other diseases of pericardium	0.647	0.353	0.000
I44.1 Atrioventricular block, second degree	0.647	0.353	0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.646	0.354	0.000
C44.8 Overlapping lesion of skin	0.645	0.355	0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.645	0.355	0.000
G43.1 Migraine with aura [classical migraine]	0.645	0.355	0.000
I68 Cerebrovascular disorders in diseases classified elsewhere	0.644	0.355	0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.644	0.355	0.000
I62 Other nontraumatic intracranial haemorrhage	0.644	0.355	0.000
D09 Carcinoma in situ of other and unspecified sites	0.644	0.356	0.000
D02 Carcinoma in situ of middle ear and respiratory system	0.644	0.356	0.000
D01 Carcinoma in situ of other and unspecified digestive organs	0.644	0.356	0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.644	0.356	0.000
I20.1 Angina pectoris with documented spasm	0.644	0.356	0.000
I52 Other heart disorders in diseases classified elsewhere	0.644	0.356	0.000
I48 Atrial fibrillation and flutter	0.644	0.356	0.000
I43 Cardiomyopathy in diseases classified elsewhere	0.644	0.356	0.000
I41 Myocarditis in diseases classified elsewhere	0.644	0.356	0.000
I40 Acute myocarditis	0.644	0.356	0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.644	0.356	0.000
I37 Pulmonary valve disorders	0.644	0.356	0.000
I32 Pericarditis in diseases classified elsewhere	0.644	0.356	0.000
I30 Acute pericarditis	0.644	0.356	0.000
H53.2 Diplopia	0.644	0.356	0.000
I24.1 Dressler's syndrome	0.644	0.356	0.000
S40 Superficial injury of shoulder and upper arm	0.644	0.356	0.000
H54 Blindness and low vision	0.642	0.358	0.000
C50-C50 Malignant neoplasm of breast	0.642	0.358	0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.641	0.359	0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction	0.640	0.360	0.000
F02 Dementia in other diseases classified elsewhere	0.640	0.360	0.000
F00 Dementia in Alzheimer's disease	0.640	0.360	0.000
F09 Unspecified organic or symptomatic mental disorder	0.640	0.360	0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances	0.640	0.360	0.000
I28 Other diseases of pulmonary vessels	0.640	0.360	0.000
Q38-Q45 Other congenital malformations of the digestive system	0.639	0.360	0.000
M47 Spondylosis	0.639	0.361	0.000
I69.3 Sequelae of cerebral infarction	0.639	0.361	0.000
N60.2 Fibroadenosis of breast	0.638	0.362	0.000
C71 Malignant neoplasm of brain	0.638	0.362	0.000
Y60-Y69 Misadventures to patients during surgical and medical care	0.638	0.362	0.000
Chapter VIII Diseases of the ear and mastoid process	0.636	0.364	0.000
F31.8 Other bipolar affective disorders	0.636	0.364	0.000
F31.7 Bipolar affective disorder, currently in remission	0.636	0.364	0.000
F31.6 Bipolar affective disorder, current episode mixed	0.636	0.364	0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms	0.636	0.364	0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms	0.636	0.364	0.000
F31.3 Bipolar affective disorder, current episode mild or moderate depression	0.636	0.364	0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms	0.636	0.364	0.000
D04.3 Skin of other and unspecified parts of face	0.636	0.364	0.000
J80-J84 Other respiratory diseases principally affecting the interstitium	0.634	0.366	0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)	0.634	0.366	0.000
C57 Malignant neoplasm of other and unspecified female genital organs	0.633	0.367	0.000
C51 Malignant neoplasm of vulva	0.633	0.367	0.000
C58 Malignant neoplasm of placenta	0.633	0.367	0.000
C55 Malignant neoplasm of uterus, part unspecified	0.633	0.367	0.000
C52 Malignant neoplasm of vagina	0.633	0.367	0.000
I73.0 Raynaud's syndrome	0.633	0.367	0.000
H53.1 Subjective visual disturbances	0.632	0.367	0.000
I61 Intracerebral haemorrhage	0.632	0.367	0.000
M11 Other crystal arthropathies	0.632	0.367	0.000
C26 Malignant neoplasm of other and ill-defined digestive organs	0.632	0.368	0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.632	0.368	0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.632	0.368	0.000
C21 Malignant neoplasm of anus and anal canal	0.632	0.368	0.000
C17 Malignant neoplasm of small intestine	0.632	0.368	0.000
C23 Malignant neoplasm of gallbladder	0.632	0.368	0.000
I79.2 Peripheral angiopathy in diseases classified elsewhere	0.632	0.368	0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.632	0.368	0.000
O66 Other obstructed labour	0.631	0.369	0.000
J09-J18 Influenza and pneumonia	0.631	0.369	0.000
C44.1 Skin of eyelid, including canthus	0.630	0.369	0.000
I60.9 Subarachnoid haemorrhage, unspecified	0.630	0.370	0.000
G44 Other headache syndromes	0.629	0.370	0.000
D04.5 Skin of trunk	0.629	0.371	0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified	0.629	0.371	0.000
M06.0 Seronegative rheumatoid arthritis	0.629	0.371	0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.628	0.372	0.000
J40-J47 Chronic lower respiratory diseases	0.628	0.372	0.000
D47.2 Monoclonal gammopathy	0.627	0.372	0.000
O03 Spontaneous abortion	0.627	0.373	0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.627	0.373	0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.627	0.373	0.000
F18 Mental and behavioural disorders due to use of volatile solvents	0.627	0.373	0.000
F16 Mental and behavioural disorders due to use of hallucinogens	0.627	0.373	0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.627	0.373	0.000
F14 Mental and behavioural disorders due to use of cocaine	0.627	0.373	0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.627	0.373	0.000
F12 Mental and behavioural disorders due to use of cannabinoids	0.627	0.373	0.000
F11 Mental and behavioural disorders due to use of opioids	0.627	0.373	0.000
H30-H36 Disorders of choroid and retina	0.626	0.374	0.000
N60.8 Other benign mammary dysplasias	0.626	0.374	0.000
J95-J99 Other diseases of the respiratory system	0.626	0.374	0.000
G47.9 Sleep disorder, unspecified	0.625	0.375	0.000
N03.9 Unspecified	0.625	0.375	0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified	0.624	0.376	0.000
Q80-Q89 Other congenital malformations	0.624	0.376	0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system	0.624	0.376	0.000
Q35-Q37 Cleft lip and cleft palate	0.624	0.376	0.000
Q30-Q34 Congenital malformations of the respiratory system	0.624	0.376	0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck	0.624	0.376	0.000
C34 Malignant neoplasm of bronchus and lung	0.624	0.376	0.000
N07 Hereditary nephropathy, not elsewhere classified	0.623	0.376	0.000
N06 Isolated proteinuria with specified morphological lesion	0.623	0.376	0.000
N05 Unspecified nephritic syndrome	0.623	0.376	0.000
N04 Nephrotic syndrome	0.623	0.376	0.000
N01 Rapidly progressive nephritic syndrome	0.623	0.376	0.000
N00 Acute nephritic syndrome	0.623	0.376	0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations