TreeWAS – Variant ID: rs1370967

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
Chapter I Certain infectious and parasitic diseases	0.992	0.008
# Top node	0.991	0.009
Chapter II Neoplasms	0.989	0.011
A30-A49 Other bacterial diseases	0.989	0.011
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.989	0.011
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.988	0.012
A41 Other septicaemia	0.981	0.019
C78.0 Secondary malignant neoplasm of lung	0.976	0.024
S00-S09 Injuries to the head	0.966	0.034
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.965	0.035
A41.9 Septicaemia, unspecified	0.962	0.038
S00 Superficial injury of head	0.957	0.043
I60-I69 Cerebrovascular diseases	0.951	0.049
Chapter IX Diseases of the circulatory system	0.950	0.050
B35-B49 Mycoses	0.949	0.051
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum	0.949	0.051
D37-D48 Neoplasms of uncertain or unknown behaviour	0.947	0.053
Chapter XX External causes of morbidity and mortality	0.930	0.070
I69 Sequelae of cerebrovascular disease	0.924	0.076
B37 Candidiasis	0.920	0.080
I67 Other cerebrovascular diseases	0.908	0.092
S00.8 Superficial injury of other parts of head	0.901	0.099
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.901	0.099
Chapter VIII Diseases of the ear and mastoid process	0.897	0.103
A41.5 Septicaemia due to other Gram-negative organisms	0.893	0.107
B37.8 Candidiasis of other sites	0.892	0.108
I67.8 Other specified cerebrovascular diseases	0.888	0.112
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction	0.884	0.116
I63 Cerebral infarction	0.883	0.117
S00.9 Superficial injury of head, part unspecified	0.874	0.126
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.872	0.128
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.870	0.130
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs	0.869	0.131
S00.0 Superficial injury of scalp	0.869	0.131
Y40 Systemic antibiotics	0.862	0.138
S01 Open wound of head	0.861	0.139
Chapter V Mental and behavioural disorders	0.860	0.140
Chapter XXII Codes for special purposes	0.852	0.148
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.851	0.149
H90-H95 Other disorders of ear	0.841	0.159
I26 Pulmonary embolism	0.834	0.166
A46 Erysipelas	0.833	0.166
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour	0.831	0.169
C78.7 Secondary malignant neoplasm of liver	0.829	0.171
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis	0.818	0.182
B90-B94 Sequelae of infectious and parasitic diseases	0.818	0.182
C78.2 Secondary malignant neoplasm of pleura	0.813	0.187
I63.9 Cerebral infarction, unspecified	0.812	0.188
S06 Intracranial injury	0.812	0.188
R47-R49 Symptoms and signs involving speech and voice	0.807	0.193
D41 Neoplasm of uncertain or unknown behaviour of urinary organs	0.807	0.193
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.807	0.193
A41.1 Septicaemia due to other specified staphylococcus	0.806	0.194
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.805	0.195
A15-A19 Tuberculosis	0.801	0.199
Y57 Other and unspecified drugs and medicaments	0.799	0.201
S01.5 Open wound of lip and oral cavity	0.794	0.206
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.794	0.206
H65-H75 Diseases of middle ear and mastoid	0.792	0.208
C80 Malignant neoplasm without specification of site	0.791	0.209
Y40.9 Systemic antibiotic, unspecified	0.789	0.211
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.786	0.214
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.785	0.215
D00-D09 In situ neoplasms	0.784	0.216
T15-T19 Effects of foreign body entering through natural orifice	0.780	0.220
C51-C58 Malignant neoplasms of female genital organs	0.775	0.225
A40 Streptococcal septicaemia	0.774	0.226
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.773	0.226
S09 Other and unspecified injuries of head	0.772	0.228
I64 Stroke, not specified as haemorrhage or infarction	0.771	0.229
A48 Other bacterial diseases, not elsewhere classified	0.771	0.229
F00-F09 Organic, including symptomatic, mental disorders	0.769	0.231
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system	0.768	0.232
B99-B99 Other infectious diseases	0.768	0.232
Chapter VI Diseases of the nervous system	0.768	0.232
Y40.0 Penicillins	0.768	0.232
R91 Abnormal findings on diagnostic imaging of lung	0.768	0.232
B37.0 Candidal stomatitis	0.764	0.236
R41 Other symptoms and signs involving cognitive functions and awareness	0.758	0.242
B15-B19 Viral hepatitis	0.758	0.242
S00.5 Superficial injury of lip and oral cavity	0.756	0.244
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified	0.755	0.245
S05 Injury of eye and orbit	0.751	0.249
D37.7 Other digestive organs	0.750	0.250
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use	0.750	0.250
B00 Herpesviral [herpes simplex] infections	0.749	0.251
T20-T25 Burns and corrosions of external body surface, specified by site	0.747	0.253
S02 Fracture of skull and facial bones	0.747	0.253
C78.5 Secondary malignant neoplasm of large intestine and rectum	0.747	0.253
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.746	0.254
I69.1 Sequelae of intracerebral haemorrhage	0.746	0.254
G35-G37 Demyelinating diseases of the central nervous system	0.745	0.255
I61 Intracerebral haemorrhage	0.743	0.257
I67.0 Dissection of cerebral arteries, nonruptured	0.743	0.257
R47 Speech disturbances, not elsewhere classified	0.742	0.258
Y51 Drugs primarily affecting the autonomic nervous system	0.741	0.259
F10 Mental and behavioural disorders due to use of alcohol	0.740	0.260
I69.3 Sequelae of cerebral infarction	0.739	0.261
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs	0.734	0.266
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.733	0.267
H90 Conductive and sensorineural hearing loss	0.733	0.267
G35 Multiple sclerosis	0.733	0.267
C78.1 Secondary malignant neoplasm of mediastinum	0.729	0.271
R80-R82 Abnormal findings on examination of urine, without diagnosis	0.728	0.272
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries	0.727	0.273
V01-V09 Pedestrian injured in transport accident	0.726	0.274
B65-B83 Helminthiases	0.725	0.275
S10-S19 Injuries to the neck	0.724	0.276
S00.2 Other superficial injuries of eyelid and periocular area	0.723	0.277
V40-V49 Car occupant injured in transport accident	0.716	0.284
Y00-Y09 Assault	0.714	0.286
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.714	0.286
A49 Bacterial infection of unspecified site	0.714	0.286
B85-B89 Pediculosis, acariasis and other infestations	0.711	0.288
B50-B64 Protozoal diseases	0.711	0.288
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.711	0.288
A75-A79 Rickettsioses	0.711	0.288
A70-A74 Other diseases caused by chlamydiae	0.711	0.288
A65-A69 Other spirochaetal diseases	0.711	0.288
A20-A28 Certain zoonotic bacterial diseases	0.711	0.288
D37.4 Colon	0.711	0.289
Chapter XVI Certain conditions originating in the perinatal period	0.711	0.289
H66 Suppurative and unspecified otitis media	0.711	0.289
R41.0 Disorientation, unspecified	0.710	0.290
C40-C41 Malignant neoplasms of bone and articular cartilage	0.709	0.291
A44 Bartonellosis	0.709	0.291
A43 Nocardiosis	0.709	0.291
A42 Actinomycosis	0.709	0.291
A39 Meningococcal infection	0.709	0.291
A37 Whooping cough	0.709	0.291
A36 Diphtheria	0.709	0.291
A32 Listeriosis	0.709	0.291
A31 Infection due to other mycobacteria	0.709	0.291
A30 Leprosy [Hansen's disease]	0.709	0.291
A38 Scarlet fever	0.709	0.291
A35 Other tetanus	0.709	0.291
A34 Obstetrical tetanus	0.709	0.291
A33 Tetanus neonatorum	0.709	0.291
C78.4 Secondary malignant neoplasm of small intestine	0.709	0.291
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs	0.709	0.291
C76 Malignant neoplasm of other and ill-defined sites	0.709	0.291
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.708	0.292
C15-C26 Malignant neoplasms of digestive organs	0.707	0.293
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.706	0.294
R40 Somnolence, stupor and coma	0.706	0.294
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.706	0.294
V80-V89 Other land transport accidents	0.705	0.295
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.704	0.296
A41.4 Septicaemia due to anaerobes	0.703	0.297
A41.3 Septicaemia due to Haemophilus influenzae	0.703	0.297
A41.2 Septicaemia due to unspecified staphylococcus	0.703	0.297
X40-X49 Accidental poisoning by and exposure to noxious substances	0.703	0.297
Y60-Y69 Misadventures to patients during surgical and medical care	0.701	0.299
D39 Neoplasm of uncertain or unknown behaviour of female genital organs	0.700	0.300
S90-S99 Injuries to the ankle and foot	0.700	0.300
F10.0 Acute intoxication	0.698	0.302
X60-X84 Intentional self-harm	0.698	0.302
R49 Voice disturbances	0.697	0.303
D45 Polycythaemia vera	0.697	0.303
B20-B24 Human immunodeficiency virus [HIV] disease	0.694	0.306
I63.4 Cerebral infarction due to embolism of cerebral arteries	0.694	0.306
B91 Sequelae of poliomyelitis	0.693	0.307
A50-A64 Infections with a predominantly sexual mode of transmission	0.692	0.307
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites	0.692	0.307
S08 Traumatic amputation of part of head	0.692	0.307
S07 Crushing injury of head	0.692	0.307
S04 Injury of cranial nerves	0.692	0.307
S03 Dislocation, sprain and strain of joints and ligaments of head	0.692	0.307
T33-T35 Frostbite	0.692	0.308
T26-T28 Burns and corrosions confined to eye and internal organs	0.692	0.308
T00-T07 Injuries involving multiple body regions	0.692	0.308
S40-S49 Injuries to the shoulder and upper arm	0.691	0.309
H92 Otalgia and effusion of ear	0.690	0.310
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue	0.689	0.310
A41.0 Septicaemia due to Staphylococcus aureus	0.689	0.311
Y57.9 Drug or medicament, unspecified	0.687	0.313
S00.4 Superficial injury of ear	0.686	0.314
R45 Symptoms and signs involving emotional state	0.685	0.315
X58-X59 Accidental exposure to other and unspecified factors	0.685	0.315
S01.2 Open wound of nose	0.683	0.317
R47.0 Dysphasia and aphasia	0.683	0.317
C77.3 Axillary and upper limb lymph nodes	0.682	0.318
I68 Cerebrovascular disorders in diseases classified elsewhere	0.682	0.318
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction	0.682	0.318
I60 Subarachnoid haemorrhage	0.682	0.318
I00-I02 Acute rheumatic fever	0.681	0.319
B48 Other mycoses, not elsewhere classified	0.681	0.319
B47 Mycetoma	0.681	0.319
B46 Zygomycosis	0.681	0.319
B45 Cryptococcosis	0.681	0.319
B44 Aspergillosis	0.681	0.319
B43 Chromomycosis and phaeomycotic abscess	0.681	0.319
B42 Sporotrichosis	0.681	0.319
B41 Paracoccidioidomycosis	0.681	0.319
B40 Blastomycosis	0.681	0.319
B39 Histoplasmosis	0.681	0.319
B38 Coccidioidomycosis	0.681	0.319
B36 Other superficial mycoses	0.681	0.319
B49 Unspecified mycosis	0.681	0.319
G30-G32 Other degenerative diseases of the nervous system	0.680	0.320
S06.6 Traumatic subarachnoid haemorrhage	0.679	0.321
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands	0.679	0.321
D42 Neoplasm of uncertain or unknown behaviour of meninges	0.679	0.321
D40 Neoplasm of uncertain or unknown behaviour of male genital organs	0.679	0.321
D37.2 Small intestine	0.679	0.321
X50-X57 Overexertion, travel and privation	0.679	0.321
U80 Agent resistant to penicillin and related antibiotics	0.679	0.321
D41.4 Bladder	0.678	0.322
W20-W49 Exposure to inanimate mechanical forces	0.677	0.323
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.676	0.324
F99-F99 Unspecified mental disorder	0.674	0.326
V20-V29 Motorcycle rider injured in transport accident	0.672	0.328
R94 Abnormal results of function studies	0.672	0.328
C43-C44 Melanoma and other malignant neoplasms of skin	0.672	0.328
S01.0 Open wound of scalp	0.671	0.328
A00-A09 Intestinal infectious diseases	0.671	0.329
D04 Carcinoma in situ of skin	0.671	0.329
S00.7 Multiple superficial injuries of head	0.671	0.329
T31 Burns classified according to extent of body surface involved	0.671	0.329
F10.1 Harmful use	0.670	0.330
R92 Abnormal findings on diagnostic imaging of breast	0.670	0.330
D80-D89 Certain disorders involving the immune mechanism	0.669	0.331
B35 Dermatophytosis	0.669	0.331
F06 Other mental disorders due to brain damage and dysfunction and to physical disease	0.668	0.332
T66-T78 Other and unspecified effects of external causes	0.668	0.332
F00 Dementia in Alzheimer's disease	0.667	0.333
Y35-Y36 Legal intervention and operations of war	0.667	0.333
Y10-Y34 Event of undetermined intent	0.667	0.333
X85-X99 Assault	0.667	0.333
X30-X39 Exposure to forces of nature	0.667	0.333
X20-X29 Contact with venomous animals and plants	0.667	0.333
X10-X19 Contact with heat and hot substances	0.667	0.333
X00-X09 Exposure to smoke, fire and flames	0.667	0.333
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.667	0.333
W75-W84 Other accidental threats to breathing	0.667	0.333
W65-W74 Accidental drowning and submersion	0.667	0.333
W50-W64 Exposure to animate mechanical forces	0.667	0.333
V98-V99 Other and unspecified transport accidents	0.667	0.333
V95-V97 Air and space transport accidents	0.667	0.333
V90-V94 Water transport accidents	0.667	0.333
V70-V79 Bus occupant injured in transport accident	0.667	0.333
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.667	0.333
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.667	0.333
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.667	0.333
C60-C63 Malignant neoplasms of male genital organs	0.665	0.335
V10-V19 Pedal cyclist injured in transport accident	0.664	0.336
A16 Respiratory tuberculosis, not confirmed bacteriologically or histologically	0.664	0.336
I69.8 Sequelae of other and unspecified cerebrovascular diseases	0.662	0.337
I69.2 Sequelae of other nontraumatic intracranial haemorrhage	0.662	0.337
I69.0 Sequelae of subarachnoid haemorrhage	0.662	0.337
S01.4 Open wound of cheek and temporomandibular area	0.662	0.338
R44 Other symptoms and signs involving general sensations and perceptions	0.661	0.339
T58 Toxic effect of carbon monoxide	0.661	0.339
Y52 Agents primarily affecting the cardiovascular system	0.661	0.339
B37.7 Candidal septicaemia	0.660	0.340
B37.6 Candidal endocarditis	0.660	0.340
B37.5 Candidal meningitis	0.660	0.340
B37.4 Candidiasis of other urogenital sites	0.660	0.340
B37.2 Candidiasis of skin and nail	0.660	0.340
B37.1 Pulmonary candidiasis	0.660	0.340
B37.3 Candidiasis of vulva and vagina	0.660	0.340
H74 Other disorders of middle ear and mastoid	0.659	0.341
B07 Viral warts	0.658	0.342
A80-A89 Viral infections of the central nervous system	0.657	0.342
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified	0.657	0.343
D37.1 Stomach	0.656	0.344
I62 Other nontraumatic intracranial haemorrhage	0.655	0.345
H91 Other hearing loss	0.655	0.345
I63.3 Cerebral infarction due to thrombosis of cerebral arteries	0.655	0.345
Y57.5 X-ray contrast media	0.651	0.349
I67.7 Cerebral arteritis, not elsewhere classified	0.651	0.349
I67.6 Nonpyogenic thrombosis of intracranial venous system	0.651	0.349
I67.5 Moyamoya disease	0.651	0.349
I67.4 Hypertensive encephalopathy	0.651	0.349
I67.3 Progressive vascular leukoencephalopathy	0.651	0.349
S01.9 Open wound of head, part unspecified	0.650	0.350
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.649	0.350
B02 Zoster [herpes zoster]	0.649	0.351
S00.3 Superficial injury of nose	0.648	0.352
R80 Isolated proteinuria	0.648	0.352
I05-I09 Chronic rheumatic heart diseases	0.647	0.353
C45 Mesothelioma	0.646	0.354
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs	0.646	0.354
Y59 Other and unspecified vaccines and biological substances	0.646	0.354
Y58 Bacterial vaccines	0.646	0.354
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs	0.646	0.354
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system	0.646	0.354
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism	0.646	0.354
Y53 Agents primarily affecting the gastro-intestinal system	0.646	0.354
Y50 Central nervous system stimulants, not elsewhere classified	0.646	0.354
Y49 Psychotropic drugs, not elsewhere classified	0.646	0.354
Y48 Anaesthetics and therapeutic gases	0.646	0.354
Y47 Sedatives, hypnotics and antianxiety drugs	0.646	0.354
Y46 Antiepileptics and anti-Parkinsonism drugs	0.646	0.354
Y41 Other systemic anti-infectives and antiparasitics	0.646	0.354
Chapter VII Diseases of the eye and adnexa	0.644	0.356
C80.0 Malignant neoplasm, primary site unknown, so stated	0.642	0.358
R42 Dizziness and giddiness	0.641	0.359
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.641	0.359
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified	0.641	0.359
T79-T79 Certain early complications of trauma	0.640	0.360
D43.2 Brain, unspecified	0.640	0.360
B25-B34 Other viral diseases	0.640	0.360
R40.0 Somnolence	0.637	0.363
R47.1 Dysarthria and anarthria	0.637	0.363
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic	0.633	0.367
I63.1 Cerebral infarction due to embolism of precerebral arteries	0.633	0.367
I63.0 Cerebral infarction due to thrombosis of precerebral arteries	0.633	0.367
I63.8 Other cerebral infarction	0.632	0.368
B00.1 Herpesviral vesicular dermatitis	0.631	0.369
D41.0 Kidney	0.631	0.369
F80-F89 Disorders of psychological development	0.629	0.371
H90.3 Sensorineural hearing loss, bilateral	0.629	0.371
C49 Malignant neoplasm of other connective and soft tissue	0.627	0.373
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified	0.627	0.373
S06.2 Diffuse brain injury	0.627	0.373
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs	0.626	0.374
T59 Toxic effect of other gases, fumes and vapours	0.626	0.374
I28 Other diseases of pulmonary vessels	0.625	0.374
C56 Malignant neoplasm of ovary	0.625	0.375
I61.4 Intracerebral haemorrhage in cerebellum	0.624	0.376
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness	0.624	0.376
B06 Rubella [German measles]	0.624	0.376
B05 Measles	0.624	0.376
B01 Varicella [chickenpox]	0.624	0.376
B09 Unspecified viral infection characterised by skin and mucous membrane lesions	0.624	0.376
B04 Monkeypox	0.624	0.376
B03 Smallpox	0.624	0.376
C53 Malignant neoplasm of cervix uteri	0.624	0.376
D37.9 Digestive organ, unspecified	0.623	0.377
D37.6 Liver, gallbladder and bile ducts	0.623	0.377
D37.3 Appendix	0.623	0.377
D37.0 Lip, oral cavity and pharynx	0.623	0.377
S06.4 Epidural haemorrhage	0.622	0.378
G80-G83 Cerebral palsy and other paralytic syndromes	0.621	0.378
T16 Foreign body in ear	0.620	0.380
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.620	0.380
S09.8 Other specified injuries of head	0.620	0.380
C71 Malignant neoplasm of brain	0.619	0.381
R70-R79 Abnormal findings on examination of blood, without diagnosis	0.619	0.381
R49.0 Dysphonia	0.618	0.382
C19 Malignant neoplasm of rectosigmoid junction	0.618	0.382
Y40.8 Other systemic antibiotics	0.618	0.382
Y40.7 Antifungal antibiotics, systemically used	0.618	0.382
Y40.6 Rifamycins	0.618	0.382
Y40.5 Aminoglycosides	0.618	0.382
Y40.4 Tetracyclines	0.618	0.382
Y40.3 Macrolides	0.618	0.382
Y40.2 Chloramphenicol group	0.618	0.382
Y40.1 Cefalosporins and other -lactam antibiotics	0.618	0.382
S01.7 Multiple open wounds of head	0.617	0.382
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.617	0.383
F70-F79 Mental retardation	0.617	0.383
U82-U85 Resistance to antimicrobial and antineoplastic drugs	0.617	0.383
D50-D53 Nutritional anaemias	0.615	0.385
A48.1 Legionnaires' disease	0.614	0.386
H66.3 Other chronic suppurative otitis media	0.613	0.387
H93 Other disorders of ear, not elsewhere classified	0.613	0.387
W00-W19 Falls	0.611	0.389
F60-F69 Disorders of adult personality and behaviour	0.611	0.389
R95-R99 Ill-defined and unknown causes of mortality	0.610	0.390
H30-H36 Disorders of choroid and retina	0.610	0.390
D07 Carcinoma in situ of other and unspecified genital organs	0.608	0.391
T17 Foreign body in respiratory tract	0.608	0.392
B99 Other and unspecified infectious diseases	0.608	0.392
H92.1 Otorrhoea	0.607	0.393
S01.3 Open wound of ear	0.606	0.394
D46 Myelodysplastic syndromes	0.605	0.394
A41.8 Other specified septicaemia	0.604	0.396
D86 Sarcoidosis	0.604	0.396
H94 Other disorders of ear in diseases classified elsewhere	0.603	0.397
A49.0 Staphylococcal infection, unspecified	0.602	0.398
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction	0.601	0.399
I67.2 Cerebral atherosclerosis	0.601	0.399
D37.5 Rectum	0.600	0.400
S70-S79 Injuries to the hip and thigh	0.599	0.401
I26.0 Pulmonary embolism with mention of acute cor pulmonale	0.598	0.402
C77.9 Lymph node, unspecified	0.598	0.402
A40.9 Streptococcal septicaemia, unspecified	0.597	0.403
S05.9 Injury of eye and orbit, part unspecified	0.597	0.403
R90 Abnormal findings on diagnostic imaging of central nervous system	0.596	0.404
R46 Symptoms and signs involving appearance and behaviour	0.596	0.404
R43 Disturbances of smell and taste	0.596	0.404
F06.7 Mild cognitive disorder	0.596	0.404
B00.9 Herpesviral infection, unspecified	0.594	0.406
H70 Mastoiditis and related conditions	0.592	0.408
D09 Carcinoma in situ of other and unspecified sites	0.591	0.409
B37.9 Candidiasis, unspecified	0.591	0.409
H90.1 Conductive hearing loss, unilateral with unrestricted hearing on the contralateral side	0.591	0.409
U80.1 Methicillin resistant agent	0.591	0.409
T20 Burn and corrosion of head and neck	0.591	0.409
Y42.0 Glucocorticoids and synthetic analogs	0.590	0.410
H66.9 Otitis media, unspecified	0.590	0.410
C26 Malignant neoplasm of other and ill-defined digestive organs	0.589	0.411
S20-S29 Injuries to the thorax	0.588	0.412
B94 Sequelae of other and unspecified infectious and parasitic diseases	0.586	0.414
B90 Sequelae of tuberculosis	0.586	0.414
B92 Sequelae of leprosy	0.586	0.414
S80-S89 Injuries to the knee and lower leg	0.585	0.415
S06.60 Traumatic subarachnoid haemorrhage (without open intracranial wound)	0.584	0.416
G30 Alzheimer's disease	0.583	0.417
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.583	0.417
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.583	0.417
T31.0 Burns involving less than 10% of body surface	0.583	0.417
S06.8 Other intracranial injuries	0.583	0.417
A40.8 Other streptococcal septicaemia	0.582	0.418
S06.9 Intracranial injury, unspecified	0.582	0.418
S06.7 Intracranial injury with prolonged coma	0.582	0.418
S06.1 Traumatic cerebral oedema	0.582	0.418
H73 Other disorders of tympanic membrane	0.581	0.418
C24 Malignant neoplasm of other and unspecified parts of biliary tract	0.580	0.420
V04 Pedestrian injured in collision with heavy transport vehicle or bus	0.579	0.421
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified	0.579	0.421
D41.9 Urinary organ, unspecified	0.579	0.421
D41.7 Other urinary organs	0.579	0.421
D41.3 Urethra	0.579	0.421
D41.2 Ureter	0.579	0.421
D41.1 Renal pelvis	0.579	0.421
C80.9 Malignant neoplasm, unspecified	0.578	0.422
Chapter XII Diseases of the skin and subcutaneous tissue	0.578	0.422
B18 Chronic viral hepatitis	0.577	0.423
S06.3 Focal brain injury	0.577	0.423
C47 Malignant neoplasm of peripheral nerves and autonomic nervous system	0.577	0.423
C46 Kaposi's sarcoma	0.577	0.423
R45.1 Restlessness and agitation	0.577	0.423
A04 Other bacterial intestinal infections	0.576	0.424
D51 Vitamin B12 deficiency anaemia	0.576	0.424
A19 Miliary tuberculosis	0.574	0.426
A18 Tuberculosis of other organs	0.574	0.426
A17 Tuberculosis of nervous system	0.574	0.426
A15 Respiratory tuberculosis, bacteriologically and histologically confirmed	0.574	0.426
S02.8 Fractures of other skull and facial bones	0.574	0.426
C05 Malignant neoplasm of palate	0.573	0.426
Y57.8 Other drugs and medicaments	0.573	0.427
Y57.7 Vitamins, not elsewhere classified	0.573	0.427
Y57.6 Other diagnostic agents	0.573	0.427
Y57.4 Pharmaceutical excipients	0.573	0.427
Y57.3 Alcohol deterrents	0.573	0.427
Y57.2 Antidotes and chelating agents, not elsewhere classified	0.573	0.427
Y57.1 Lipotropic drugs	0.573	0.427
Y57.0 Appetite depressants [anorectics]	0.573	0.427
C77.8 Lymph nodes of multiple regions	0.572	0.428
S09.9 Unspecified injury of head	0.571	0.429
D04.3 Skin of other and unspecified parts of face	0.571	0.429
H71 Cholesteatoma of middle ear	0.570	0.430
T32 Corrosions classified according to extent of body surface involved	0.569	0.431
T30 Burn and corrosion, body region unspecified	0.569	0.431
T29 Burns and corrosions of multiple body regions	0.569	0.431
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere	0.568	0.432
H69 Other disorders of Eustachian tube	0.568	0.432
H68 Eustachian salpingitis and obstruction	0.568	0.432
H67 Otitis media in diseases classified elsewhere	0.568	0.432
F05 Delirium, not induced by alcohol and other psychoactive substances	0.566	0.434
Y42.8 Other and unspecified hormones and their synthetic substitutes	0.566	0.434
A16.2 Tuberculosis of lung, without mention of bacteriological or histological confirmation	0.566	0.434
H35 Other retinal disorders	0.564	0.436
F01 Vascular dementia	0.564	0.436
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.564	0.436
F18 Mental and behavioural disorders due to use of volatile solvents	0.564	0.436
F16 Mental and behavioural disorders due to use of hallucinogens	0.564	0.436
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.564	0.436
F14 Mental and behavioural disorders due to use of cocaine	0.564	0.436
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.564	0.436
F12 Mental and behavioural disorders due to use of cannabinoids	0.564	0.436
F11 Mental and behavioural disorders due to use of opioids	0.564	0.436
S02.6 Fracture of mandible	0.563	0.437
S01.1 Open wound of eyelid and periocular area	0.563	0.437
T65 Toxic effect of other and unspecified substances	0.563	0.437
T63 Toxic effect of contact with venomous animals	0.563	0.437
T62 Toxic effect of other noxious substances eaten as food	0.563	0.437
T61 Toxic effect of noxious substances eaten as seafood	0.563	0.437
T60 Toxic effect of pesticides	0.563	0.437
T57 Toxic effect of other inorganic substances	0.563	0.437
T56 Toxic effect of metals	0.563	0.437
T54 Toxic effect of corrosive substances	0.563	0.437
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone	0.563	0.437
T52 Toxic effect of organic solvents	0.563	0.437
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants	0.563	0.437
T55 Toxic effect of soaps and detergents	0.563	0.437
C48 Malignant neoplasm of retroperitoneum and peritoneum	0.562	0.438
D02 Carcinoma in situ of middle ear and respiratory system	0.562	0.438
D01 Carcinoma in situ of other and unspecified digestive organs	0.562	0.438
D00 Carcinoma in situ of oral cavity, oesophagus and stomach	0.562	0.438
C22 Malignant neoplasm of liver and intrahepatic bile ducts	0.562	0.438
I67.9 Cerebrovascular disease, unspecified	0.561	0.439
D48.6 Breast	0.561	0.439
F00.0 Dementia in Alzheimer's disease with early onset	0.560	0.440
Y44 Agents primarily affecting blood constituents	0.560	0.440
Y00 Assault by blunt object	0.560	0.440
T19 Foreign body in genito-urinary tract	0.559	0.440
T15 Foreign body on external eye	0.559	0.440
R41.2 Retrograde amnesia	0.558	0.442
C44 Other malignant neoplasms of skin	0.558	0.442
Q80-Q89 Other congenital malformations	0.558	0.442
B17 Other acute viral hepatitis	0.558	0.442
S06.0 Concussion	0.557	0.443
C57 Malignant neoplasm of other and unspecified female genital organs	0.556	0.444
C51 Malignant neoplasm of vulva	0.556	0.444
C58 Malignant neoplasm of placenta	0.556	0.444
C52 Malignant neoplasm of vagina	0.556	0.444

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations