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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139479025
log Bayes Factor = 5.02873
Chromosome 10   position 71,880,301  (GRCh37) Explore rs139479025 on Ensembl!
Variant rs139479025 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
0.999 0.001 0.000
I20 Angina pectoris
0.975 0.025 0.000
Chapter VII Diseases of the eye and adnexa
0.971 0.029 0.000
I25.2 Old myocardial infarction
0.970 0.030 0.000
Chapter XIV Diseases of the genitourinary system
0.958 0.042 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.952 0.048 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.940 0.060 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.936 0.064 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.935 0.065 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.922 0.078 0.000
I20.9 Angina pectoris, unspecified
0.917 0.083 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.910 0.090 0.000
H25-H28 Disorders of lens
0.909 0.091 0.000
I25.1 Atherosclerotic heart disease
0.900 0.100 0.000
Chapter XI Diseases of the digestive system
0.894 0.106 0.000
Chapter X Diseases of the respiratory system
0.892 0.108 0.000
I20.0 Unstable angina
0.890 0.110 0.000
I60-I69 Cerebrovascular diseases
0.888 0.112 0.000
Chapter II Neoplasms
0.886 0.114 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.871 0.129 0.000
S00-S09 Injuries to the head
0.858 0.142 0.000
Chapter VI Diseases of the nervous system
0.856 0.144 0.000
H30-H36 Disorders of choroid and retina
0.853 0.147 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.844 0.156 0.000
J40-J47 Chronic lower respiratory diseases
0.834 0.166 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.832 0.168 0.000
H25 Senile cataract
0.830 0.170 0.000
E10-E14 Diabetes mellitus
0.829 0.171 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.818 0.182 0.000
R07 Pain in throat and chest
0.813 0.187 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.811 0.189 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.809 0.190 0.000
M45-M49 Spondylopathies
0.807 0.193 0.000
M65-M68 Disorders of synovium and tendon
0.798 0.202 0.000
C44 Other malignant neoplasms of skin
0.794 0.206 0.000
I21 Acute myocardial infarction
0.794 0.206 0.000
E70-E90 Metabolic disorders
0.787 0.213 0.000
I63 Cerebral infarction
0.779 0.221 0.000
N10-N16 Renal tubulo-interstitial diseases
0.779 0.221 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.777 0.223 0.000
Chapter VIII Diseases of the ear and mastoid process
0.776 0.223 0.000
R07.3 Other chest pain
0.771 0.229 0.000
M05-M14 Inflammatory polyarthropathies
0.767 0.233 0.000
H26 Other cataract
0.763 0.237 0.000
N60-N64 Disorders of breast
0.762 0.238 0.000
N93 Other abnormal uterine and vaginal bleeding
0.759 0.241 0.000
C44.3 Skin of other and unspecified parts of face
0.758 0.242 0.000
R00 Abnormalities of heart beat
0.757 0.243 0.000
M40-M43 Deforming dorsopathies
0.750 0.250 0.000
S60-S69 Injuries to the wrist and hand
0.748 0.252 0.000
R07.2 Precordial pain
0.748 0.252 0.000
N89 Other noninflammatory disorders of vagina
0.747 0.253 0.000
C15-C26 Malignant neoplasms of digestive organs
0.747 0.253 0.000
J45 Asthma
0.745 0.255 0.000
K70-K77 Diseases of liver
0.745 0.255 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.744 0.256 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.741 0.259 0.000
M15-M19 Arthrosis
0.740 0.260 0.000
K90-K93 Other diseases of the digestive system
0.740 0.260 0.000
S01 Open wound of head
0.737 0.263 0.000
I24 Other acute ischaemic heart diseases
0.736 0.264 0.000
E65-E68 Obesity and other hyperalimentation
0.734 0.265 0.000
H25.9 Senile cataract, unspecified
0.730 0.270 0.000
H25.0 Senile incipient cataract
0.728 0.272 0.000
M50-M54 Other dorsopathies
0.724 0.276 0.000
N25-N29 Other disorders of kidney and ureter
0.722 0.277 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.721 0.279 0.000
N30-N39 Other diseases of urinary system
0.719 0.281 0.000
C51-C58 Malignant neoplasms of female genital organs
0.717 0.283 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I22 Subsequent myocardial infarction
0.717 0.283 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.716 0.284 0.000
I25.5 Ischaemic cardiomyopathy
0.716 0.284 0.000
I25.4 Coronary artery aneurysm
0.716 0.284 0.000
I25.3 Aneurysm of heart
0.716 0.284 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.716 0.284 0.000
N17-N19 Renal failure
0.716 0.284 0.000
J30-J39 Other diseases of upper respiratory tract
0.715 0.285 0.000
N94.1 Dyspareunia
0.712 0.288 0.000
I30-I52 Other forms of heart disease
0.711 0.289 0.000
Chapter V Mental and behavioural disorders
0.711 0.289 0.000
S09 Other and unspecified injuries of head
0.709 0.291 0.000
M48 Other spondylopathies
0.708 0.292 0.000
S00 Superficial injury of head
0.707 0.293 0.000
G40-G47 Episodic and paroxysmal disorders
0.707 0.293 0.000
N86 Erosion and ectropion of cervix uteri
0.706 0.294 0.000
J44 Other chronic obstructive pulmonary disease
0.706 0.294 0.000
H35 Other retinal disorders
0.703 0.297 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.703 0.297 0.000
M20-M25 Other joint disorders
0.703 0.297 0.000
I63.9 Cerebral infarction, unspecified
0.701 0.299 0.000
I20.8 Other forms of angina pectoris
0.699 0.301 0.000
I20.1 Angina pectoris with documented spasm
0.699 0.301 0.000
J40 Bronchitis, not specified as acute or chronic
0.696 0.304 0.000
H55-H59 Other disorders of eye and adnexa
0.696 0.304 0.000
H53-H54 Visual disturbances and blindness
0.696 0.304 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.696 0.304 0.000
H43-H45 Disorders of vitreous body and globe
0.696 0.304 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.696 0.304 0.000
H10-H13 Disorders of conjunctiva
0.696 0.304 0.000
E00-E07 Disorders of thyroid gland
0.696 0.304 0.000
H02 Other disorders of eyelid
0.694 0.306 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.692 0.308 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.691 0.309 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.691 0.309 0.000
N99-N99 Other disorders of the genitourinary system
0.687 0.313 0.000
N00-N08 Glomerular diseases
0.687 0.313 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.687 0.313 0.000
E11 Non-insulin-dependent diabetes mellitus
0.684 0.316 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.683 0.317 0.000
M91-M94 Chondropathies
0.683 0.317 0.000
M86-M90 Other osteopathies
0.683 0.317 0.000
M60-M63 Disorders of muscles
0.683 0.317 0.000
M00-M03 Infectious arthropathies
0.683 0.317 0.000
J45.9 Asthma, unspecified
0.682 0.318 0.000
H36 Retinal disorders in diseases classified elsewhere
0.681 0.319 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.681 0.319 0.000
N80 Endometriosis
0.681 0.319 0.000
E14 Unspecified diabetes mellitus
0.677 0.323 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.676 0.324 0.000
M80-M85 Disorders of bone density and structure
0.675 0.325 0.000
E50-E64 Other nutritional deficiencies
0.674 0.326 0.000
E40-E46 Malnutrition
0.674 0.326 0.000
E20-E35 Disorders of other endocrine glands
0.674 0.326 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.674 0.326 0.000
K08 Other disorders of teeth and supporting structures
0.673 0.327 0.000
R42 Dizziness and giddiness
0.673 0.327 0.000
C44.6 Skin of upper limb, including shoulder
0.671 0.329 0.000
N93.0 Postcoital and contact bleeding
0.667 0.333 0.000
M65 Synovitis and tenosynovitis
0.666 0.334 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.664 0.336 0.000
S50-S59 Injuries to the elbow and forearm
0.663 0.337 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.663 0.337 0.000
H33 Retinal detachments and breaks
0.661 0.339 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.661 0.339 0.000
T79-T79 Certain early complications of trauma
0.661 0.339 0.000
T66-T78 Other and unspecified effects of external causes
0.661 0.339 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.661 0.339 0.000
T33-T35 Frostbite
0.661 0.339 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.661 0.339 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.661 0.339 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.661 0.339 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.661 0.339 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.661 0.339 0.000
T00-T07 Injuries involving multiple body regions
0.661 0.339 0.000
S90-S99 Injuries to the ankle and foot
0.661 0.339 0.000
S40-S49 Injuries to the shoulder and upper arm
0.661 0.339 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.661 0.339 0.000
S20-S29 Injuries to the thorax
0.661 0.339 0.000
S10-S19 Injuries to the neck
0.661 0.339 0.000
S80-S89 Injuries to the knee and lower leg
0.661 0.339 0.000
G20-G26 Extrapyramidal and movement disorders
0.660 0.340 0.000
J00-J06 Acute upper respiratory infections
0.657 0.343 0.000
M06 Other rheumatoid arthritis
0.656 0.343 0.000
K92 Other diseases of digestive system
0.656 0.344 0.000
D00-D09 In situ neoplasms
0.656 0.344 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.654 0.346 0.000
N98 Complications associated with artificial fertilisation
0.653 0.347 0.000
N97 Female infertility
0.653 0.347 0.000
N91 Absent, scanty and rare menstruation
0.653 0.347 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.653 0.347 0.000
N88 Other noninflammatory disorders of cervix uteri
0.653 0.347 0.000
N87 Dysplasia of cervix uteri
0.653 0.347 0.000
N82 Fistulae involving female genital tract
0.653 0.347 0.000
N96 Habitual aborter
0.653 0.347 0.000
H40-H42 Glaucoma
0.652 0.348 0.000
H28 Cataract and other disorders of lens in diseases classified elsewhere
0.652 0.348 0.000
H27 Other disorders of lens
0.652 0.348 0.000
N13 Obstructive and reflux uropathy
0.651 0.349 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.650 0.350 0.000
H26.9 Cataract, unspecified
0.649 0.351 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.649 0.351 0.000
G47 Sleep disorders
0.649 0.351 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.646 0.354 0.000
N35 Urethral stricture
0.645 0.355 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.644 0.355 0.000
E87.5 Hyperkalaemia
0.644 0.356 0.000
R47-R49 Symptoms and signs involving speech and voice
0.642 0.358 0.000
N95 Menopausal and other perimenopausal disorders
0.641 0.359 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.640 0.360 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.640 0.360 0.000
J60-J70 Lung diseases due to external agents
0.640 0.360 0.000
K76 Other diseases of liver
0.638 0.361 0.000
M48.0 Spinal stenosis
0.638 0.362 0.000
N40-N51 Diseases of male genital organs
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.637 0.362 0.000
I69 Sequelae of cerebrovascular disease
0.637 0.363 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.637 0.363 0.000
I67 Other cerebrovascular diseases
0.637 0.363 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.637 0.363 0.000
I62 Other nontraumatic intracranial haemorrhage
0.637 0.363 0.000
I61 Intracerebral haemorrhage
0.637 0.363 0.000
I60 Subarachnoid haemorrhage
0.637 0.363 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.637 0.363 0.000
R00.2 Palpitations
0.636 0.364 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.635 0.365 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.635 0.365 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.635 0.365 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.635 0.365 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.635 0.365 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.635 0.365 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.635 0.365 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.635 0.365 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.635 0.365 0.000
J90-J94 Other diseases of pleura
0.634 0.366 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.634 0.366 0.000
M17 Gonarthrosis [arthrosis of knee]
0.633 0.367 0.000
S01.0 Open wound of scalp
0.632 0.368 0.000
Chapter I Certain infectious and parasitic diseases
0.632 0.368 0.000
K35-K38 Diseases of appendix
0.632 0.368 0.000
J09-J18 Influenza and pneumonia
0.630 0.369 0.000
E10 Insulin-dependent diabetes mellitus
0.630 0.370 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.630 0.370 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.630 0.370 0.000
R00.1 Bradycardia, unspecified
0.629 0.371 0.000
K05 Gingivitis and periodontal diseases
0.627 0.373 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.625 0.375 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.624 0.375 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.624 0.375 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.623 0.377 0.000
N63 Unspecified lump in breast
0.622 0.378 0.000
I73 Other peripheral vascular diseases
0.621 0.379 0.000
I74 Arterial embolism and thrombosis
0.619 0.381 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.619 0.381 0.000
N81 Female genital prolapse
0.617 0.383 0.000
N94.6 Dysmenorrhoea, unspecified
0.617 0.383 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.617 0.383 0.000
I77 Other disorders of arteries and arterioles
0.615 0.384 0.000
S08 Traumatic amputation of part of head
0.615 0.385 0.000
S07 Crushing injury of head
0.615 0.385 0.000
S06 Intracranial injury
0.615 0.385 0.000
S05 Injury of eye and orbit
0.615 0.385 0.000
S04 Injury of cranial nerves
0.615 0.385 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.615 0.385 0.000
S02 Fracture of skull and facial bones
0.615 0.385 0.000
G90-G99 Other disorders of the nervous system
0.614 0.386 0.000
G70-G73 Diseases of myoneural junction and muscle
0.614 0.386 0.000
G30-G32 Other degenerative diseases of the nervous system
0.614 0.386 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.614 0.386 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.614 0.386 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.612 0.388 0.000
M70-M79 Other soft tissue disorders
0.612 0.388 0.000
H34 Retinal vascular occlusions
0.612 0.388 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.612 0.388 0.000
H31 Other disorders of choroid
0.612 0.388 0.000
H30 Chorioretinal inflammation
0.612 0.388 0.000
K55-K64 Other diseases of intestines
0.611 0.389 0.000
C20 Malignant neoplasm of rectum
0.610 0.390 0.000
Chapter XX External causes of morbidity and mortality
0.610 0.390 0.000
M67 Other disorders of synovium and tendon
0.609 0.391 0.000
H65-H75 Diseases of middle ear and mastoid
0.607 0.393 0.000
J95-J99 Other diseases of the respiratory system
0.606 0.394 0.000
R06 Abnormalities of breathing
0.605 0.394 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.605 0.395 0.000
R01 Cardiac murmurs and other cardiac sounds
0.605 0.395 0.000
R02 Gangrene, not elsewhere classified
0.605 0.395 0.000
K22 Other diseases of oesophagus
0.604 0.396 0.000
D10-D36 Benign neoplasms
0.604 0.396 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.604 0.396 0.000
H02.8 Other specified disorders of eyelid
0.603 0.397 0.000
S09.9 Unspecified injury of head
0.603 0.397 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.602 0.398 0.000
H25.8 Other senile cataract
0.601 0.399 0.000
S61 Open wound of wrist and hand
0.598 0.402 0.000
J41 Simple and mucopurulent chronic bronchitis
0.598 0.402 0.000
J46 Status asthmaticus
0.598 0.402 0.000
J42 Unspecified chronic bronchitis
0.598 0.402 0.000
K13 Other diseases of lip and oral mucosa
0.597 0.403 0.000
C43 Malignant melanoma of skin
0.597 0.403 0.000
C54 Malignant neoplasm of corpus uteri
0.596 0.404 0.000
H25.2 Senile cataract, morgagnian type
0.595 0.405 0.000
E13 Other specified diabetes mellitus
0.594 0.406 0.000
E12 Malnutrition-related diabetes mellitus
0.594 0.406 0.000
K08.3 Retained dental root
0.593 0.407 0.000
N35.9 Urethral stricture, unspecified
0.592 0.408 0.000
K65-K67 Diseases of peritoneum
0.591 0.408 0.000
M17.1 Other primary gonarthrosis
0.591 0.409 0.000
J43 Emphysema
0.590 0.410 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.589 0.411 0.000
C44.2 Skin of ear and external auricular canal
0.589 0.411 0.000
M48.06 Spinal stenosis (Lumbar region)
0.587 0.412 0.000
E66 Obesity
0.587 0.413 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.586 0.413 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.586 0.414 0.000
N94.9 Unspecified condition associated with female genital organs and menstrual cycle
0.586 0.414 0.000
N94.5 Secondary dysmenorrhoea
0.586 0.414 0.000
N94.4 Primary dysmenorrhoea
0.586 0.414 0.000
N94.3 Premenstrual tension syndrome
0.586 0.414 0.000
N94.2 Vaginismus
0.586 0.414 0.000
N94.0 Mittelschmerz
0.586 0.414 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.584 0.416 0.000
M41 Scoliosis
0.584 0.416 0.000
H35.8 Other specified retinal disorders
0.583 0.417 0.000
R07.1 Chest pain on breathing
0.583 0.417 0.000
R07.0 Pain in throat
0.583 0.417 0.000
C44.7 Skin of lower limb, including hip
0.582 0.417 0.000
N85.4 Malposition of uterus
0.582 0.418 0.000
C64-C68 Malignant neoplasms of urinary tract
0.582 0.418 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.581 0.418 0.000
I78 Diseases of capillaries
0.581 0.418 0.000
I72 Other aneurysm
0.581 0.418 0.000
I71 Aortic aneurysm and dissection
0.581 0.418 0.000
I70 Atherosclerosis
0.581 0.418 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.580 0.419 0.000
H05 Disorders of orbit
0.580 0.419 0.000
H04 Disorders of lachrymal system
0.580 0.419 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.580 0.419 0.000
H01 Other inflammation of eyelid
0.580 0.419 0.000
K50-K52 Noninfective enteritis and colitis
0.580 0.420 0.000
H00 Hordeolum and chalazion
0.580 0.420 0.000
N85.0 Endometrial glandular hyperplasia
0.579 0.421 0.000
M49 Spondylopathies in diseases classified elsewhere
0.578 0.421 0.000
M46 Other inflammatory spondylopathies
0.578 0.421 0.000
M45 Ankylosing spondylitis
0.578 0.421 0.000
K22.2 Oesophageal obstruction
0.578 0.422 0.000
M06.9 Rheumatoid arthritis, unspecified
0.577 0.423 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.576 0.424 0.000
S00.0 Superficial injury of scalp
0.576 0.424 0.000
I10-I15 Hypertensive diseases
0.575 0.424 0.000
R00.0 Tachycardia, unspecified
0.575 0.425 0.000
S62 Fracture at wrist and hand level
0.573 0.427 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.572 0.428 0.000
M66 Spontaneous rupture of synovium and tendon
0.572 0.428 0.000
K40-K46 Hernia
0.571 0.429 0.000
C15 Malignant neoplasm of oesophagus
0.571 0.429 0.000
I65.2 Occlusion and stenosis of carotid artery
0.571 0.429 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.570 0.430 0.000
C44.8 Overlapping lesion of skin
0.570 0.430 0.000
C44.4 Skin of scalp and neck
0.570 0.430 0.000
C44.0 Skin of lip
0.570 0.430 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.569 0.431 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.569 0.431 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.569 0.431 0.000
E14.9 Without complications
0.568 0.432 0.000
G47.3 Sleep apnoea
0.567 0.433 0.000
I21.4 Acute subendocardial myocardial infarction
0.567 0.433 0.000
H80-H83 Diseases of inner ear
0.566 0.434 0.000
S01.8 Open wound of other parts of head
0.565 0.434 0.000
E11.9 Without complications
0.565 0.435 0.000
H26.4 After-cataract
0.565 0.435 0.000
M47 Spondylosis
0.565 0.435 0.000
M43 Other deforming dorsopathies
0.565 0.435 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.564 0.436 0.000
E88 Other metabolic disorders
0.564 0.436 0.000
E85 Amyloidosis
0.564 0.436 0.000
E84 Cystic fibrosis
0.564 0.436 0.000
E83 Disorders of mineral metabolism
0.564 0.436 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.564 0.436 0.000
E79 Disorders of purine and pyrimidine metabolism
0.564 0.436 0.000
E77 Disorders of glycoprotein metabolism
0.564 0.436 0.000
E76 Disorders of glycosaminoglycan metabolism
0.564 0.436 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.564 0.436 0.000
E74 Other disorders of carbohydrate metabolism
0.564 0.436 0.000
E73 Lactose intolerance
0.564 0.436 0.000
E72 Other disorders of amino-acid metabolism
0.564 0.436 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.564 0.436 0.000
E70 Disorders of aromatic amino-acid metabolism
0.564 0.436 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.564 0.436 0.000
R04 Haemorrhage from respiratory passages
0.564 0.436 0.000
K63 Other diseases of intestine
0.564 0.436 0.000
C50-C50 Malignant neoplasm of breast
0.563 0.436 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.561 0.439 0.000
H90-H95 Other disorders of ear
0.561 0.439 0.000
K04 Diseases of pulp and periapical tissues
0.559 0.441 0.000
I63.8 Other cerebral infarction
0.559 0.441 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.559 0.441 0.000
I63.5 Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteries
0.559 0.441 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.559 0.441 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.559 0.441 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.559 0.441 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.559 0.441 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.559 0.441 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.558 0.441 0.000
N15 Other renal tubulo-interstitial diseases
0.558 0.441 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.558 0.441 0.000
N11 Chronic tubulo-interstitial nephritis
0.558 0.441 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.558 0.441 0.000
N10 Acute tubulo-interstitial nephritis
0.558 0.441 0.000
H36.0 Diabetic retinopathy
0.558 0.442 0.000
M65.3 Trigger finger
0.557 0.443 0.000
K14 Diseases of tongue
0.557 0.443 0.000
K12 Stomatitis and related lesions
0.557 0.443 0.000
K11 Diseases of salivary glands
0.557 0.443 0.000
K10 Other diseases of jaws
0.557 0.443 0.000
K09 Cysts of oral region, not elsewhere classified
0.557 0.443 0.000
K07 Dentofacial anomalies [including malocclusion]
0.557 0.443 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.557 0.443 0.000
K03 Other diseases of hard tissues of teeth
0.557 0.443 0.000
K00 Disorders of tooth development and eruption
0.557 0.443 0.000
H60-H62 Diseases of external ear
0.557 0.443 0.000
C44.1 Skin of eyelid, including canthus
0.556 0.444 0.000
G47.9 Sleep disorder, unspecified
0.555 0.445 0.000
S00.9 Superficial injury of head, part unspecified
0.555 0.445 0.000
M16 Coxarthrosis [arthrosis of hip]
0.554 0.446 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.554 0.446 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.553 0.447 0.000
M23 Internal derangement of knee
0.553 0.447 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.551 0.449 0.000
J33 Nasal polyp
0.550 0.449 0.000
M14 Arthropathies in other diseases classified elsewhere
0.550 0.450 0.000
M12 Other specific arthropathies
0.550 0.450 0.000
M11 Other crystal arthropathies
0.550 0.450 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.550 0.450 0.000
M08 Juvenile arthritis
0.550 0.450 0.000
M07 Psoriatic and enteropathic arthropathies
0.550 0.450 0.000
M05 Seropositive rheumatoid arthritis
0.550 0.450 0.000
I44 Atrioventricular and left bundle-branch block
0.549 0.451 0.000
M10 Gout
0.549 0.451 0.000
N92 Excessive, frequent and irregular menstruation
0.549 0.451 0.000
M54 Dorsalgia
0.549 0.451 0.000
J32 Chronic sinusitis
0.547 0.452 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.547 0.453 0.000
H26.8 Other specified cataract
0.547 0.453 0.000
H26.3 Drug-induced cataract
0.547 0.453 0.000
H26.2 Complicated cataract
0.547 0.453 0.000
H26.1 Traumatic cataract
0.547 0.453 0.000
H26.0 Infantile, juvenile and presenile cataract
0.547 0.453 0.000
N64 Other disorders of breast
0.547 0.453 0.000
N60 Benign mammary dysplasia
0.547 0.453 0.000
N62 Hypertrophy of breast
0.547 0.453 0.000
N61 Inflammatory disorders of breast
0.547 0.453 0.000
I24.8 Other forms of acute ischaemic heart disease
0.546 0.453 0.000
J44.0 Chronic obstructive pulmonary disease with acute lower respiratory infection
0.545 0.455 0.000
N93.8 Other specified abnormal uterine and vaginal bleeding
0.544 0.456 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.544 0.456 0.000
N13.2 Hydronephrosis with renal and ureteral calculous obstruction
0.543 0.457 0.000
G35 Multiple sclerosis
0.543 0.457 0.000
K92.0 Haematemesis
0.543 0.457 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.543 0.457 0.000
K92.1 Melaena
0.541 0.459 0.000
K63.8 Other specified diseases of intestine
0.541 0.459 0.000
G25 Other extrapyramidal and movement disorders
0.539 0.461 0.000
N18 Chronic renal failure
0.538 0.462 0.000
M42 Spinal osteochondrosis
0.538 0.462 0.000
M40 Kyphosis and lordosis
0.538 0.462 0.000
R26 Abnormalities of gait and mobility
0.538 0.462 0.000
S69 Other and unspecified injuries of wrist and hand
0.537 0.463 0.000
S68 Traumatic amputation of wrist and hand
0.537 0.463 0.000
S67 Crushing injury of wrist and hand
0.537 0.463 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.537 0.463 0.000
S65 Injury of blood vessels at wrist and hand level
0.537 0.463 0.000
S64 Injury of nerves at wrist and hand level
0.537 0.463 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.537 0.463 0.000
S60 Superficial injury of wrist and hand
0.537 0.463 0.000
N83.2 Other and unspecified ovarian cysts
0.536 0.464 0.000
N89.9 Noninflammatory disorder of vagina, unspecified
0.535 0.464 0.000
N89.7 Haematocolpos
0.535 0.464 0.000
N89.6 Tight hymenal ring
0.535 0.464 0.000
N89.5 Stricture and atresia of vagina
0.535 0.464 0.000
N89.4 Leukoplakia of vagina
0.535 0.464 0.000
N89.3 Dysplasia of vagina, unspecified
0.535 0.464 0.000
N89.2 Severe vaginal dysplasia, not elsewhere classified
0.535 0.464 0.000
N89.1 Moderate vaginal dysplasia
0.535 0.464 0.000
N89.0 Mild vaginal dysplasia
0.535 0.464 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.535 0.465 0.000
C25 Malignant neoplasm of pancreas
0.535 0.465 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.535 0.465 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.535 0.465 0.000
C21 Malignant neoplasm of anus and anal canal
0.535 0.465 0.000
C18 Malignant neoplasm of colon
0.535 0.465 0.000
C17 Malignant neoplasm of small intestine
0.535 0.465 0.000
C16 Malignant neoplasm of stomach
0.535 0.465 0.000
C23 Malignant neoplasm of gallbladder
0.535 0.465 0.000
J45.8 Mixed asthma
0.534 0.465 0.000
J45.1 Nonallergic asthma
0.534 0.465 0.000
J45.0 Predominantly allergic asthma
0.534 0.465 0.000
K77 Liver disorders in diseases classified elsewhere
0.534 0.466 0.000
K75 Other inflammatory liver diseases
0.534 0.466 0.000
K74 Fibrosis and cirrhosis of liver
0.534 0.466 0.000
K73 Chronic hepatitis, not elsewhere classified
0.534 0.466 0.000
K72 Hepatic failure, not elsewhere classified
0.534 0.466 0.000
K71 Toxic liver disease
0.534 0.466 0.000
K70 Alcoholic liver disease
0.534 0.466 0.000
I31 Other diseases of pericardium
0.534 0.466 0.000
R46 Symptoms and signs involving appearance and behaviour
0.534 0.466 0.000
R45 Symptoms and signs involving emotional state
0.534 0.466 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.534 0.466 0.000
R43 Disturbances of smell and taste
0.534 0.466 0.000
R40 Somnolence, stupor and coma
0.534 0.466 0.000
M51 Other intervertebral disk disorders
0.533 0.467 0.000
I42 Cardiomyopathy
0.533 0.467 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.532 0.468 0.000
N85.7 Haematometra
0.532 0.468 0.000
N85.6 Intra-uterine synechiae
0.532 0.468 0.000
N85.5 Inversion of uterus
0.532 0.468 0.000
N85.3 Subinvolution of uterus
0.532 0.468 0.000
N85.1 Endometrial adenomatous hyperplasia
0.532 0.468 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.531 0.469 0.000
M18 Arthrosis of first carpometacarpal joint
0.531 0.469 0.000
M15 Polyarthrosis
0.531 0.469 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.530 0.470 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.530 0.470 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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