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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs139877884
log Bayes Factor = 13.2633
Chromosome 7   position 146,019,105  (GRCh37) Explore rs139877884 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter I Certain infectious and parasitic diseases
1.000 0.000 0.000
Chapter XI Diseases of the digestive system
0.999 0.001 0.000
B95-B98 Bacterial, viral and other infectious agents
0.999 0.001 0.000
Chapter VI Diseases of the nervous system
0.998 0.002 0.000
I30-I52 Other forms of heart disease
0.998 0.002 0.000
Chapter IX Diseases of the circulatory system
0.998 0.002 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.994 0.006 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
M54 Dorsalgia
0.988 0.012 0.000
K70-K77 Diseases of liver
0.988 0.012 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.987 0.013 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
K90-K93 Other diseases of the digestive system
0.977 0.023 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.977 0.023 0.000
Chapter XX External causes of morbidity and mortality
0.970 0.030 0.000
E70-E90 Metabolic disorders
0.970 0.030 0.000
Chapter VII Diseases of the eye and adnexa
0.968 0.032 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.963 0.037 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.963 0.037 0.000
M80-M85 Disorders of bone density and structure
0.956 0.044 0.000
B96.2 Escherichia coli [E. coli] as the cause of diseases classified to other chapters
0.954 0.046 0.000
I44 Atrioventricular and left bundle-branch block
0.946 0.054 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.936 0.064 0.000
E83 Disorders of mineral metabolism
0.936 0.064 0.000
M54.9 Dorsalgia, unspecified
0.933 0.067 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.932 0.068 0.000
G40-G47 Episodic and paroxysmal disorders
0.932 0.068 0.000
H53-H54 Visual disturbances and blindness
0.930 0.070 0.000
I51 Complications and ill-defined descriptions of heart disease
0.929 0.071 0.000
I45 Other conduction disorders
0.929 0.071 0.000
K08 Other disorders of teeth and supporting structures
0.927 0.073 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.924 0.076 0.000
K92 Other diseases of digestive system
0.922 0.078 0.000
K70 Alcoholic liver disease
0.919 0.081 0.000
M40-M43 Deforming dorsopathies
0.916 0.084 0.000
G90-G99 Other disorders of the nervous system
0.914 0.086 0.000
G35 Multiple sclerosis
0.912 0.088 0.000
K76 Other diseases of liver
0.911 0.089 0.000
H53 Visual disturbances
0.909 0.091 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.903 0.097 0.000
M54.5 Low back pain
0.903 0.097 0.000
M54.4 Lumbago with sciatica
0.902 0.098 0.000
E83.5 Disorders of calcium metabolism
0.901 0.099 0.000
I47 Paroxysmal tachycardia
0.900 0.100 0.000
K92.1 Melaena
0.899 0.101 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.899 0.101 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.899 0.101 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.898 0.102 0.000
S00-S09 Injuries to the head
0.893 0.107 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.888 0.112 0.000
I05-I09 Chronic rheumatic heart diseases
0.888 0.112 0.000
A30-A49 Other bacterial diseases
0.882 0.118 0.000
K76.6 Portal hypertension
0.879 0.121 0.000
I45.1 Other and unspecified right bundle-branch block
0.875 0.125 0.000
K50-K52 Noninfective enteritis and colitis
0.873 0.127 0.000
I49 Other cardiac arrhythmias
0.872 0.128 0.000
M70-M79 Other soft tissue disorders
0.871 0.129 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.871 0.129 0.000
I42 Cardiomyopathy
0.868 0.132 0.000
I44.7 Left bundle-branch block, unspecified
0.858 0.142 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.856 0.144 0.000
H53.8 Other visual disturbances
0.856 0.144 0.000
K08.3 Retained dental root
0.855 0.145 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.854 0.146 0.000
S32 Fracture of lumbar spine and pelvis
0.853 0.147 0.000
M81 Osteoporosis without pathological fracture
0.851 0.149 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.851 0.149 0.000
A00-A09 Intestinal infectious diseases
0.847 0.153 0.000
M65-M68 Disorders of synovium and tendon
0.844 0.156 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.839 0.161 0.000
I51.8 Other ill-defined heart diseases
0.839 0.161 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.836 0.164 0.000
S50-S59 Injuries to the elbow and forearm
0.831 0.169 0.000
E40-E46 Malnutrition
0.830 0.170 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.830 0.170 0.000
M54.56 Low back pain (Lumbar region)
0.830 0.170 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.829 0.171 0.000
K65-K67 Diseases of peritoneum
0.828 0.172 0.000
G37 Other demyelinating diseases of central nervous system
0.826 0.174 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.826 0.174 0.000
G47 Sleep disorders
0.825 0.175 0.000
Y43 Primarily systemic agents
0.825 0.175 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.825 0.175 0.000
K74 Fibrosis and cirrhosis of liver
0.824 0.176 0.000
S70-S79 Injuries to the hip and thigh
0.824 0.176 0.000
E86 Volume depletion
0.822 0.178 0.000
I33 Acute and subacute endocarditis
0.820 0.180 0.000
S10-S19 Injuries to the neck
0.818 0.182 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.817 0.183 0.000
K70.3 Alcoholic cirrhosis of liver
0.816 0.184 0.000
I44.2 Atrioventricular block, complete
0.816 0.184 0.000
W00-W19 Falls
0.816 0.184 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.815 0.185 0.000
Y52 Agents primarily affecting the cardiovascular system
0.813 0.187 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.812 0.188 0.000
E10-E14 Diabetes mellitus
0.812 0.188 0.000
M43 Other deforming dorsopathies
0.810 0.190 0.000
I49.9 Cardiac arrhythmia, unspecified
0.810 0.190 0.000
E83.4 Disorders of magnesium metabolism
0.808 0.192 0.000
K90 Intestinal malabsorption
0.807 0.193 0.000
G30-G32 Other degenerative diseases of the nervous system
0.806 0.194 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.804 0.196 0.000
M54.2 Cervicalgia
0.802 0.198 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.801 0.199 0.000
I50 Heart failure
0.801 0.199 0.000
K91.4 Colostomy and enterostomy malfunction
0.801 0.199 0.000
G40 Epilepsy
0.798 0.202 0.000
M54.46 Lumbago with sciatica (Lumbar region)
0.797 0.203 0.000
M54.6 Pain in thoracic spine
0.796 0.204 0.000
K08.8 Other specified disorders of teeth and supporting structures
0.795 0.205 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.793 0.207 0.000
G93 Other disorders of brain
0.791 0.209 0.000
A65-A69 Other spirochaetal diseases
0.790 0.210 0.000
H10-H13 Disorders of conjunctiva
0.789 0.211 0.000
M80 Osteoporosis with pathological fracture
0.787 0.213 0.000
S09 Other and unspecified injuries of head
0.787 0.213 0.000
I51.9 Heart disease, unspecified
0.786 0.214 0.000
H53.2 Diplopia
0.786 0.214 0.000
R15 Faecal incontinence
0.784 0.216 0.000
G91 Hydrocephalus
0.783 0.217 0.000
K75 Other inflammatory liver diseases
0.781 0.219 0.000
R17 Unspecified jaundice
0.781 0.219 0.000
H55-H59 Other disorders of eye and adnexa
0.780 0.220 0.000
S32.5 Fracture of pubis
0.777 0.223 0.000
M81.9 Osteoporosis, unspecified
0.776 0.224 0.000
K92.0 Haematemesis
0.776 0.224 0.000
I42.9 Cardiomyopathy, unspecified
0.775 0.225 0.000
Y40 Systemic antibiotics
0.775 0.225 0.000
M84 Disorders of continuity of bone
0.774 0.226 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.771 0.229 0.000
K55-K64 Other diseases of intestines
0.771 0.229 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.769 0.231 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.769 0.231 0.000
S90-S99 Injuries to the ankle and foot
0.768 0.232 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.768 0.232 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.768 0.232 0.000
M41 Scoliosis
0.767 0.233 0.000
M85 Other disorders of bone density and structure
0.766 0.234 0.000
I47.2 Ventricular tachycardia
0.766 0.234 0.000
E50-E64 Other nutritional deficiencies
0.765 0.234 0.000
M51 Other intervertebral disk disorders
0.764 0.236 0.000
I08 Multiple valve diseases
0.763 0.237 0.000
H43-H45 Disorders of vitreous body and globe
0.763 0.237 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.760 0.239 0.000
K04 Diseases of pulp and periapical tissues
0.760 0.240 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.760 0.240 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.759 0.240 0.000
K51 Ulcerative colitis
0.759 0.241 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.759 0.241 0.000
K12 Stomatitis and related lesions
0.758 0.242 0.000
I47.1 Supraventricular tachycardia
0.754 0.246 0.000
I44.3 Other and unspecified atrioventricular block
0.753 0.247 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.752 0.248 0.000
K02 Dental caries
0.752 0.248 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.751 0.249 0.000
M54.49 Lumbago with sciatica (Site unspecified)
0.750 0.249 0.000
M65 Synovitis and tenosynovitis
0.750 0.250 0.000
I45.9 Conduction disorder, unspecified
0.749 0.250 0.000
E10 Insulin-dependent diabetes mellitus
0.749 0.251 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.748 0.252 0.000
Chapter XXII Codes for special purposes
0.748 0.252 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.748 0.252 0.000
K55 Vascular disorders of intestine
0.748 0.252 0.000
E88 Other metabolic disorders
0.746 0.254 0.000
Y43.3 Other antineoplastic drugs
0.746 0.254 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.745 0.255 0.000
I38 Endocarditis, valve unspecified
0.744 0.256 0.000
G43 Migraine
0.744 0.256 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.741 0.259 0.000
T81 Complications of procedures, not elsewhere classified
0.741 0.259 0.000
M60-M63 Disorders of muscles
0.741 0.259 0.000
H53.9 Visual disturbance, unspecified
0.740 0.260 0.000
K70.9 Alcoholic liver disease, unspecified
0.739 0.260 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.738 0.262 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.737 0.263 0.000
S39 Other and unspecified injuries of abdomen, lower back and pelvis
0.737 0.263 0.000
A41 Other septicaemia
0.736 0.264 0.000
M15-M19 Arthrosis
0.735 0.265 0.000
I44.6 Other and unspecified fascicular block
0.734 0.266 0.000
K08.1 Loss of teeth due to accident, extraction or local periodontal disease
0.734 0.266 0.000
K05 Gingivitis and periodontal diseases
0.734 0.266 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.734 0.266 0.000
G62 Other polyneuropathies
0.734 0.266 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.733 0.267 0.000
I31 Other diseases of pericardium
0.732 0.268 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.730 0.270 0.000
H53.1 Subjective visual disturbances
0.730 0.270 0.000
M00-M03 Infectious arthropathies
0.728 0.272 0.000
Q60-Q64 Congenital malformations of the urinary system
0.727 0.272 0.000
R44.1 Visual hallucinations
0.727 0.273 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.727 0.273 0.000
M53 Other dorsopathies, not elsewhere classified
0.727 0.273 0.000
I05 Rheumatic mitral valve diseases
0.726 0.274 0.000
A49 Bacterial infection of unspecified site
0.726 0.274 0.000
M43.1 Spondylolisthesis
0.726 0.274 0.000
M86-M90 Other osteopathies
0.725 0.275 0.000
Y44 Agents primarily affecting blood constituents
0.725 0.275 0.000
I34 Nonrheumatic mitral valve disorders
0.724 0.276 0.000
S32.50 Fracture of pubis (closed)
0.722 0.277 0.000
R16.1 Splenomegaly, not elsewhere classified
0.722 0.278 0.000
E80.6 Other disorders of bilirubin metabolism
0.720 0.280 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.719 0.281 0.000
M54.50 Low back pain (Multiple sites in spine)
0.719 0.281 0.000
G96 Other disorders of central nervous system
0.719 0.281 0.000
Chapter II Neoplasms
0.719 0.281 0.000
E46 Unspecified protein-energy malnutrition
0.719 0.281 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B99-B99 Other infectious diseases
0.717 0.283 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.717 0.283 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.717 0.283 0.000
B65-B83 Helminthiases
0.717 0.283 0.000
B50-B64 Protozoal diseases
0.717 0.283 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.717 0.283 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.717 0.283 0.000
A75-A79 Rickettsioses
0.717 0.283 0.000
A70-A74 Other diseases caused by chlamydiae
0.717 0.283 0.000
A20-A28 Certain zoonotic bacterial diseases
0.717 0.283 0.000
A15-A19 Tuberculosis
0.717 0.283 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.716 0.284 0.000
I52 Other heart disorders in diseases classified elsewhere
0.715 0.285 0.000
I48 Atrial fibrillation and flutter
0.715 0.285 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.715 0.285 0.000
I41 Myocarditis in diseases classified elsewhere
0.715 0.285 0.000
I40 Acute myocarditis
0.715 0.285 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.715 0.285 0.000
I37 Pulmonary valve disorders
0.715 0.285 0.000
I36 Nonrheumatic tricuspid valve disorders
0.715 0.285 0.000
I32 Pericarditis in diseases classified elsewhere
0.715 0.285 0.000
I00-I02 Acute rheumatic fever
0.715 0.285 0.000
K01 Embedded and impacted teeth
0.715 0.285 0.000
I30 Acute pericarditis
0.714 0.286 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.714 0.286 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.713 0.287 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.713 0.287 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.713 0.287 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.712 0.287 0.000
T85.5 Mechanical complication of gastro-intestinal prosthetic devices, implants and grafts
0.712 0.288 0.000
S09.9 Unspecified injury of head
0.711 0.289 0.000
E80.4 Gilbert's syndrome
0.711 0.289 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.711 0.289 0.000
G47.8 Other sleep disorders
0.710 0.290 0.000
S05 Injury of eye and orbit
0.710 0.290 0.000
K70.1 Alcoholic hepatitis
0.709 0.291 0.000
S70 Superficial injury of hip and thigh
0.709 0.291 0.000
A04 Other bacterial intestinal infections
0.709 0.291 0.000
M54.8 Other dorsalgia
0.708 0.291 0.000
M54.0 Panniculitis affecting regions of neck and back
0.708 0.291 0.000
K77 Liver disorders in diseases classified elsewhere
0.708 0.292 0.000
K73 Chronic hepatitis, not elsewhere classified
0.708 0.292 0.000
K71 Toxic liver disease
0.708 0.292 0.000
M79.6 Pain in limb
0.708 0.292 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.708 0.292 0.000
K13 Other diseases of lip and oral mucosa
0.708 0.292 0.000
T33-T35 Frostbite
0.707 0.292 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.707 0.292 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.707 0.292 0.000
T00-T07 Injuries involving multiple body regions
0.707 0.292 0.000
M91-M94 Chondropathies
0.707 0.293 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.707 0.293 0.000
M81.99 Osteoporosis, unspecified (Site unspecified)
0.707 0.293 0.000
M77 Other enthesopathies
0.707 0.293 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.706 0.294 0.000
A80-A89 Viral infections of the central nervous system
0.705 0.294 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.705 0.295 0.000
C34 Malignant neoplasm of bronchus and lung
0.705 0.295 0.000
R11 Nausea and vomiting
0.704 0.296 0.000
K72 Hepatic failure, not elsewhere classified
0.703 0.297 0.000
M54.1 Radiculopathy
0.703 0.297 0.000
B15-B19 Viral hepatitis
0.702 0.298 0.000
V80-V89 Other land transport accidents
0.701 0.299 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.701 0.299 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.701 0.299 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.701 0.299 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.701 0.299 0.000
B96.1 Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters
0.700 0.300 0.000
K51.3 Ulcerative (chronic) rectosigmoiditis
0.700 0.300 0.000
R47-R49 Symptoms and signs involving speech and voice
0.700 0.300 0.000
S01 Open wound of head
0.699 0.301 0.000
G20-G26 Extrapyramidal and movement disorders
0.699 0.301 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.696 0.304 0.000
Y35-Y36 Legal intervention and operations of war
0.696 0.304 0.000
Y10-Y34 Event of undetermined intent
0.696 0.304 0.000
Y00-Y09 Assault
0.696 0.304 0.000
X85-X99 Assault
0.696 0.304 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.696 0.304 0.000
X50-X57 Overexertion, travel and privation
0.696 0.304 0.000
X30-X39 Exposure to forces of nature
0.696 0.304 0.000
X20-X29 Contact with venomous animals and plants
0.696 0.304 0.000
X10-X19 Contact with heat and hot substances
0.696 0.304 0.000
X00-X09 Exposure to smoke, fire and flames
0.696 0.304 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.696 0.304 0.000
W75-W84 Other accidental threats to breathing
0.696 0.304 0.000
W65-W74 Accidental drowning and submersion
0.696 0.304 0.000
W50-W64 Exposure to animate mechanical forces
0.696 0.304 0.000
V98-V99 Other and unspecified transport accidents
0.696 0.304 0.000
V95-V97 Air and space transport accidents
0.696 0.304 0.000
V90-V94 Water transport accidents
0.696 0.304 0.000
V70-V79 Bus occupant injured in transport accident
0.696 0.304 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.696 0.304 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.696 0.304 0.000
V40-V49 Car occupant injured in transport accident
0.696 0.304 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.696 0.304 0.000
V01-V09 Pedestrian injured in transport accident
0.696 0.304 0.000
M54.57 Low back pain (Lumbosacral region)
0.696 0.304 0.000
R06 Abnormalities of breathing
0.696 0.304 0.000
E85 Amyloidosis
0.695 0.305 0.000
E84 Cystic fibrosis
0.695 0.305 0.000
E79 Disorders of purine and pyrimidine metabolism
0.695 0.305 0.000
E77 Disorders of glycoprotein metabolism
0.695 0.305 0.000
E76 Disorders of glycosaminoglycan metabolism
0.695 0.305 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.695 0.305 0.000
E74 Other disorders of carbohydrate metabolism
0.695 0.305 0.000
E73 Lactose intolerance
0.695 0.305 0.000
E72 Other disorders of amino-acid metabolism
0.695 0.305 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.695 0.305 0.000
E70 Disorders of aromatic amino-acid metabolism
0.695 0.305 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.695 0.305 0.000
G47.3 Sleep apnoea
0.695 0.305 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.694 0.306 0.000
E20-E35 Disorders of other endocrine glands
0.694 0.306 0.000
K70.4 Alcoholic hepatic failure
0.693 0.307 0.000
R44.3 Hallucinations, unspecified
0.693 0.307 0.000
K00 Disorders of tooth development and eruption
0.693 0.307 0.000
I33.0 Acute and subacute infective endocarditis
0.692 0.308 0.000
S20-S29 Injuries to the thorax
0.691 0.309 0.000
C34.9 Bronchus or lung, unspecified
0.691 0.309 0.000
K09 Cysts of oral region, not elsewhere classified
0.690 0.310 0.000
K03 Other diseases of hard tissues of teeth
0.690 0.310 0.000
G36 Other acute disseminated demyelination
0.690 0.310 0.000
I50.1 Left ventricular failure
0.690 0.310 0.000
T79-T79 Certain early complications of trauma
0.690 0.310 0.000
G37.8 Other specified demyelinating diseases of central nervous system
0.690 0.310 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.690 0.310 0.000
G91.9 Hydrocephalus, unspecified
0.689 0.311 0.000
K55.2 Angiodysplasia of colon
0.688 0.312 0.000
A09 Diarrhoea and gastro-enteritis of presumed infectious origin
0.688 0.312 0.000
Q80-Q89 Other congenital malformations
0.688 0.312 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.687 0.313 0.000
I49.8 Other specified cardiac arrhythmias
0.686 0.314 0.000
M83 Adult osteomalacia
0.686 0.314 0.000
M82 Osteoporosis in diseases classified elsewhere
0.686 0.314 0.000
H18 Other disorders of cornea
0.686 0.314 0.000
G41 Status epilepticus
0.685 0.315 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.685 0.315 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.684 0.316 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.684 0.316 0.000
S52 Fracture of forearm
0.684 0.316 0.000
K11 Diseases of salivary glands
0.684 0.316 0.000
R06.0 Dyspnoea
0.683 0.317 0.000
G44 Other headache syndromes
0.683 0.317 0.000
M19 Other arthrosis
0.683 0.317 0.000
M79.0 Rheumatism, unspecified
0.682 0.317 0.000
I42.8 Other cardiomyopathies
0.682 0.318 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.681 0.319 0.000
K08.9 Disorder of teeth and supporting structures, unspecified
0.680 0.320 0.000
H20 Iridocyclitis
0.680 0.320 0.000
K74.3 Primary biliary cirrhosis
0.680 0.320 0.000
I44.5 Left posterior fascicular block
0.678 0.322 0.000
I44.4 Left anterior fascicular block
0.678 0.322 0.000
V20-V29 Motorcycle rider injured in transport accident
0.678 0.322 0.000
M43.16 Spondylolisthesis (Lumbar region)
0.678 0.322 0.000
G70-G73 Diseases of myoneural junction and muscle
0.676 0.324 0.000
G93.3 Postviral fatigue syndrome
0.676 0.324 0.000
K52 Other non-infective gastro-enteritis and colitis
0.675 0.325 0.000
G95 Other diseases of spinal cord
0.675 0.325 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.675 0.325 0.000
G43.1 Migraine with aura [classical migraine]
0.675 0.325 0.000
K66 Other disorders of peritoneum
0.673 0.327 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.672 0.328 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.672 0.328 0.000
Y59 Other and unspecified vaccines and biological substances
0.671 0.329 0.000
Y58 Bacterial vaccines
0.671 0.329 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.671 0.329 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.671 0.329 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.671 0.329 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.671 0.329 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.671 0.329 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.671 0.329 0.000
Y48 Anaesthetics and therapeutic gases
0.671 0.329 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.671 0.329 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.671 0.329 0.000
E83.9 Disorder of mineral metabolism, unspecified
0.671 0.329 0.000
E83.8 Other disorders of mineral metabolism
0.671 0.329 0.000
E83.2 Disorders of zinc metabolism
0.671 0.329 0.000
E83.0 Disorders of copper metabolism
0.671 0.329 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.670 0.330 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.670 0.330 0.000
T66-T78 Other and unspecified effects of external causes
0.670 0.330 0.000
K55.9 Vascular disorder of intestine, unspecified
0.669 0.331 0.000
E83.3 Disorders of phosphorus metabolism
0.669 0.331 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.669 0.331 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.669 0.331 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.669 0.331 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.669 0.331 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.669 0.331 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.669 0.331 0.000
S38 Crushing injury and traumatic amputation of part of abdomen, lower back and pelvis
0.669 0.331 0.000
S37 Injury of urinary and pelvic organs
0.669 0.331 0.000
S36 Injury of intra-abdominal organs
0.669 0.331 0.000
S35 Injury of blood vessels at abdomen, lower back and pelvis level
0.669 0.331 0.000
S34 Injury of nerves and lumbar spinal cord at abdomen, lower back and pelvis level
0.669 0.331 0.000
S33 Dislocation, sprain and strain of joints and ligaments of lumbar spine and pelvis
0.669 0.331 0.000
S31 Open wound of abdomen, lower back and pelvis
0.669 0.331 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.668 0.332 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.668 0.332 0.000
I51.7 Cardiomegaly
0.667 0.333 0.000
M54.29 Cervicalgia-Site unspe
0.667 0.333 0.000
I45.8 Other specified conduction disorders
0.666 0.334 0.000
I45.4 Nonspecific intraventricular block
0.666 0.334 0.000
I45.3 Trifascicular block
0.666 0.334 0.000
I45.2 Bifascicular block
0.666 0.334 0.000
I45.0 Right fascicular block
0.666 0.334 0.000
I51.6 Cardiovascular disease, unspecified
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.666 0.334 0.000
I51.4 Myocarditis, unspecified
0.666 0.334 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.666 0.334 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.666 0.334 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.666 0.334 0.000
I51.0 Cardiac septal defect, acquired
0.666 0.334 0.000
H30-H36 Disorders of choroid and retina
0.666 0.334 0.000
W08 Fall involving other furniture
0.665 0.335 0.000
S19 Other and unspecified injuries of neck
0.665 0.335 0.000
S56 Injury of muscle and tendon at forearm level
0.665 0.335 0.000
K08.2 Atrophy of edentulous alveolar ridge
0.665 0.335 0.000
K08.0 Exfoliation of teeth due to systemic causes
0.665 0.335 0.000
K10 Other diseases of jaws
0.665 0.335 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.664 0.336 0.000
K92.9 Disease of digestive system, unspecified
0.664 0.336 0.000
M50 Cervical disk disorders
0.663 0.336 0.000
V10-V19 Pedal cyclist injured in transport accident
0.663 0.337 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.663 0.337 0.000
R45 Symptoms and signs involving emotional state
0.663 0.337 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.662 0.337 0.000
Q00-Q07 Congenital malformations of the nervous system
0.662 0.337 0.000
K90.0 Coeliac disease
0.662 0.338 0.000
K04.8 Radicular cyst
0.662 0.338 0.000
T86 Failure and rejection of transplanted organs and tissues
0.662 0.338 0.000
M41.9 Scoliosis, unspecified
0.661 0.339 0.000
X60-X84 Intentional self-harm
0.661 0.339 0.000
K92.8 Other specified diseases of digestive system
0.661 0.339 0.000
I35 Nonrheumatic aortic valve disorders
0.661 0.339 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.661 0.339 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.659 0.341 0.000
Y40.0 Penicillins
0.659 0.341 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.659 0.341 0.000
K70.0 Alcoholic fatty liver
0.659 0.341 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.659 0.341 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.658 0.342 0.000
G37.3 Acute transverse myelitis in demyelinating disease of central nervous system
0.658 0.342 0.000
S00 Superficial injury of head
0.657 0.343 0.000
M45-M49 Spondylopathies
0.657 0.343 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
M42 Spinal osteochondrosis
0.656 0.343 0.000
M40 Kyphosis and lordosis
0.656 0.343 0.000
M19.9 Arthrosis, unspecified
0.656 0.344 0.000
E10.3 With ophthalmic complications
0.656 0.344 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.656 0.344 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.656 0.344 0.000
G90 Disorders of autonomic nervous system
0.656 0.344 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.656 0.344 0.000
G92 Toxic encephalopathy
0.656 0.344 0.000
W17 Other fall from one level to another
0.656 0.344 0.000
H10 Conjunctivitis
0.654 0.346 0.000
I44.1 Atrioventricular block, second degree
0.654 0.346 0.000
T81.5 Foreign body accidentally left in body cavity or operation wound following a procedure
0.654 0.346 0.000
B35-B49 Mycoses
0.653 0.346 0.000
K76.7 Hepatorenal syndrome
0.653 0.346 0.000
K76.5 Hepatic veno-occlusive disease
0.653 0.346 0.000
K76.4 Peliosis hepatis
0.653 0.346 0.000
K76.3 Infarction of liver
0.653 0.346 0.000
K76.2 Central haemorrhagic necrosis of liver
0.653 0.346 0.000
K76.1 Chronic passive congestion of liver
0.653 0.346 0.000
Chapter XXI Factors influencing health status and contact with health services
0.653 0.347 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.652 0.348 0.000
W20-W49 Exposure to inanimate mechanical forces
0.652 0.348 0.000
H53.6 Night blindness
0.652 0.348 0.000
H53.5 Colour vision deficiencies
0.652 0.348 0.000
H53.3 Other disorders of binocular vision
0.652 0.348 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.651 0.348 0.000
R44.0 Auditory hallucinations
0.651 0.349 0.000
I08.0 Disorders of both mitral and aortic valves
0.651 0.349 0.000
S60-S69 Injuries to the wrist and hand
0.651 0.349 0.000
E00-E07 Disorders of thyroid gland
0.651 0.349 0.000
S32.0 Fracture of lumbar vertebra
0.651 0.349 0.000
A41.9 Septicaemia, unspecified
0.651 0.349 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.650 0.350 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.649 0.350 0.000
A46 Erysipelas
0.649 0.350 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.648 0.352 0.000
M54.55 Low back pain (Thoracolumbar region)
0.647 0.353 0.000
M54.54 Low back pain-Thoracic
0.647 0.353 0.000
M54.53 Low back pain-Cervicothoracic
0.647 0.353 0.000
M54.52 Low back pain-Cervical
0.647 0.353 0.000
M54.51 Low back pain-Occipit-atl-axl
0.647 0.353 0.000
K76.8 Other specified diseases of liver
0.647 0.353 0.000
Y41.8 Other specified systemic anti-infectives and antiparasitics
0.647 0.353 0.000
G62.8 Other specified polyneuropathies
0.647 0.353 0.000
M05-M14 Inflammatory polyarthropathies
0.647 0.353 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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