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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs142030651
log Bayes Factor = 17.2897
Chromosome 22   position 41,513,727  (GRCh37) Explore rs142030651 on Ensembl!
Variant rs142030651 is part of Cluster X0005

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter VII Diseases of the eye and adnexa
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.999 0.001 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
Chapter XXI Factors influencing health status and contact with health services
0.998 0.002 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.998 0.002 0.000
I25.1 Atherosclerotic heart disease
0.993 0.007 0.000
J09-J18 Influenza and pneumonia
0.992 0.008 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.988 0.012 0.000
J18 Pneumonia, organism unspecified
0.986 0.014 0.000
F30-F39 Mood [affective] disorders
0.983 0.017 0.000
J30-J39 Other diseases of upper respiratory tract
0.983 0.017 0.000
F41 Other anxiety disorders
0.980 0.020 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.980 0.020 0.000
I25.2 Old myocardial infarction
0.977 0.023 0.000
F41.9 Anxiety disorder, unspecified
0.975 0.025 0.000
H30-H36 Disorders of choroid and retina
0.975 0.025 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.974 0.026 0.000
J34 Other disorders of nose and nasal sinuses
0.972 0.028 0.000
F32 Depressive episode
0.970 0.030 0.000
Chapter II Neoplasms
0.969 0.031 0.000
R00 Abnormalities of heart beat
0.960 0.040 0.000
J18.9 Pneumonia, unspecified
0.959 0.041 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.959 0.041 0.000
H33 Retinal detachments and breaks
0.958 0.042 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.957 0.043 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.954 0.046 0.000
F32.9 Depressive episode, unspecified
0.952 0.048 0.000
E10-E14 Diabetes mellitus
0.951 0.049 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.949 0.051 0.000
I20 Angina pectoris
0.949 0.051 0.000
H53-H54 Visual disturbances and blindness
0.945 0.055 0.000
J18.1 Lobar pneumonia, unspecified
0.940 0.060 0.000
C44 Other malignant neoplasms of skin
0.939 0.061 0.000
R07 Pain in throat and chest
0.937 0.063 0.000
C44.3 Skin of other and unspecified parts of face
0.930 0.070 0.000
E65-E68 Obesity and other hyperalimentation
0.929 0.071 0.000
R06 Abnormalities of breathing
0.926 0.074 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.923 0.077 0.000
E11 Non-insulin-dependent diabetes mellitus
0.919 0.081 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.918 0.082 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.918 0.082 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.916 0.084 0.000
J34.2 Deviated nasal septum
0.911 0.089 0.000
H52 Disorders of refraction and accommodation
0.910 0.090 0.000
H33.2 Serous retinal detachment
0.910 0.090 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.910 0.090 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.908 0.092 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.904 0.096 0.000
H40-H42 Glaucoma
0.903 0.097 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.903 0.097 0.000
O00-O08 Pregnancy with abortive outcome
0.902 0.098 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.900 0.100 0.000
R00.2 Palpitations
0.898 0.102 0.000
R05 Cough
0.896 0.104 0.000
E66 Obesity
0.896 0.104 0.000
E11.9 Without complications
0.894 0.106 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.893 0.107 0.000
Z95.1 Presence of aortocoronary bypass graft
0.891 0.109 0.000
R07.4 Chest pain, unspecified
0.886 0.114 0.000
Z03.4 Observation for suspected myocardial infarction
0.872 0.128 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.870 0.130 0.000
Z92 Personal history of medical treatment
0.867 0.133 0.000
R06.5 Mouth breathing
0.866 0.134 0.000
E66.9 Obesity, unspecified
0.866 0.134 0.000
H53 Visual disturbances
0.863 0.137 0.000
H52.1 Myopia
0.862 0.138 0.000
Z37 Outcome of delivery
0.860 0.140 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.857 0.143 0.000
J90-J94 Other diseases of pleura
0.856 0.144 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.853 0.147 0.000
Z93 Artificial opening status
0.850 0.150 0.000
J35 Chronic diseases of tonsils and adenoids
0.847 0.153 0.000
I25.5 Ischaemic cardiomyopathy
0.847 0.153 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.847 0.153 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.840 0.160 0.000
S20-S29 Injuries to the thorax
0.838 0.162 0.000
I24 Other acute ischaemic heart diseases
0.836 0.164 0.000
H40 Glaucoma
0.834 0.166 0.000
R47-R49 Symptoms and signs involving speech and voice
0.834 0.166 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.832 0.168 0.000
C44.6 Skin of upper limb, including shoulder
0.829 0.171 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.828 0.172 0.000
R07.2 Precordial pain
0.827 0.173 0.000
S80-S89 Injuries to the knee and lower leg
0.826 0.174 0.000
E14 Unspecified diabetes mellitus
0.823 0.177 0.000
O03 Spontaneous abortion
0.823 0.177 0.000
F32.3 Severe depressive episode with psychotic symptoms
0.823 0.177 0.000
I20.0 Unstable angina
0.822 0.178 0.000
R25 Abnormal involuntary movements
0.821 0.179 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.820 0.180 0.000
R00.1 Bradycardia, unspecified
0.818 0.181 0.000
H54 Blindness and low vision
0.818 0.182 0.000
R30-R39 Symptoms and signs involving the urinary system
0.816 0.184 0.000
I20.9 Angina pectoris, unspecified
0.815 0.185 0.000
H33.3 Retinal breaks without detachment
0.814 0.186 0.000
Chapter I Certain infectious and parasitic diseases
0.814 0.186 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.809 0.191 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.808 0.192 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.808 0.192 0.000
J34.3 Hypertrophy of nasal turbinates
0.807 0.193 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.807 0.193 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.806 0.194 0.000
Z35 Supervision of high-risk pregnancy
0.805 0.194 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.803 0.197 0.000
Z37.0 Single live birth
0.800 0.200 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.798 0.202 0.000
H33.5 Other retinal detachments
0.797 0.203 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.795 0.205 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.794 0.206 0.000
C51-C58 Malignant neoplasms of female genital organs
0.793 0.207 0.000
I60-I69 Cerebrovascular diseases
0.793 0.207 0.000
I20.8 Other forms of angina pectoris
0.792 0.208 0.000
H43-H45 Disorders of vitreous body and globe
0.791 0.209 0.000
Chapter XXII Codes for special purposes
0.790 0.210 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.790 0.210 0.000
I21 Acute myocardial infarction
0.788 0.212 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.787 0.213 0.000
H55-H59 Other disorders of eye and adnexa
0.787 0.213 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.785 0.215 0.000
H50 Other strabismus
0.783 0.217 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.781 0.219 0.000
O36 Maternal care for other known or suspected foetal problems
0.780 0.220 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.780 0.220 0.000
Z22 Carrier of infectious disease
0.779 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.778 0.222 0.000
O60-O75 Complications of labour and delivery
0.770 0.230 0.000
E50-E64 Other nutritional deficiencies
0.767 0.233 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.766 0.234 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.765 0.235 0.000
Chapter XI Diseases of the digestive system
0.764 0.236 0.000
Z29 Need for other prophylactic measures
0.762 0.238 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.762 0.238 0.000
R31 Unspecified haematuria
0.759 0.241 0.000
R07.0 Pain in throat
0.758 0.242 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.758 0.242 0.000
R02 Gangrene, not elsewhere classified
0.758 0.242 0.000
Z12 Special screening examination for neoplasms
0.755 0.245 0.000
J30 Vasomotor and allergic rhinitis
0.754 0.246 0.000
R80 Isolated proteinuria
0.754 0.246 0.000
F31 Bipolar affective disorder
0.754 0.246 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.752 0.248 0.000
H53.4 Visual field defects
0.752 0.248 0.000
R06.6 Hiccough
0.751 0.249 0.000
R26 Abnormalities of gait and mobility
0.751 0.249 0.000
Z93.2 Ileostomy status
0.751 0.249 0.000
C44.5 Skin of trunk
0.749 0.251 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.749 0.251 0.000
Z13 Special screening examination for other diseases and disorders
0.748 0.251 0.000
Z92.3 Personal history of irradiation
0.748 0.252 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.748 0.252 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.747 0.253 0.000
H33.0 Retinal detachment with retinal break
0.745 0.255 0.000
J13 Pneumonia due to Streptococcus pneumoniae
0.743 0.257 0.000
O46 Antepartum haemorrhage, not elsewhere classified
0.742 0.258 0.000
R25.1 Tremor, unspecified
0.740 0.260 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.738 0.262 0.000
K50-K52 Noninfective enteritis and colitis
0.737 0.263 0.000
I05-I09 Chronic rheumatic heart diseases
0.736 0.264 0.000
S32 Fracture of lumbar spine and pelvis
0.735 0.265 0.000
E14.9 Without complications
0.734 0.266 0.000
C15-C26 Malignant neoplasms of digestive organs
0.734 0.266 0.000
C50-C50 Malignant neoplasm of breast
0.733 0.267 0.000
H52.0 Hypermetropia
0.732 0.268 0.000
H10-H13 Disorders of conjunctiva
0.732 0.268 0.000
D80-D89 Certain disorders involving the immune mechanism
0.731 0.269 0.000
L03 Cellulitis
0.730 0.270 0.000
Z95.4 Presence of other heart-valve replacement
0.730 0.270 0.000
J90 Pleural effusion, not elsewhere classified
0.728 0.272 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.728 0.272 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.725 0.275 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.723 0.277 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.723 0.277 0.000
S82 Fracture of lower leg, including ankle
0.723 0.277 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.721 0.279 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.721 0.279 0.000
S70-S79 Injuries to the hip and thigh
0.720 0.280 0.000
T79-T79 Certain early complications of trauma
0.720 0.280 0.000
H53.2 Diplopia
0.720 0.280 0.000
O03.4 Incomplete, without complication
0.719 0.281 0.000
H34 Retinal vascular occlusions
0.719 0.281 0.000
Z89 Acquired absence of limb
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.716 0.283 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.716 0.283 0.000
O26 Maternal care for other conditions predominantly related to pregnancy
0.716 0.284 0.000
F99-F99 Unspecified mental disorder
0.716 0.284 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.284 0.000
F80-F89 Disorders of psychological development
0.716 0.284 0.000
F70-F79 Mental retardation
0.716 0.284 0.000
F60-F69 Disorders of adult personality and behaviour
0.716 0.284 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.716 0.284 0.000
J35.0 Chronic tonsillitis
0.716 0.284 0.000
R39 Other symptoms and signs involving the urinary system
0.716 0.284 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.716 0.284 0.000
E20-E35 Disorders of other endocrine glands
0.715 0.285 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.715 0.285 0.000
O00 Ectopic pregnancy
0.713 0.287 0.000
I22 Subsequent myocardial infarction
0.713 0.287 0.000
K50 Crohn's disease [regional enteritis]
0.713 0.287 0.000
J93 Pneumothorax
0.713 0.287 0.000
J18.0 Bronchopneumonia, unspecified
0.712 0.287 0.000
J17 Pneumonia in diseases classified elsewhere
0.711 0.289 0.000
J16 Pneumonia due to other infectious organisms, not elsewhere classified
0.711 0.289 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.711 0.289 0.000
J12 Viral pneumonia, not elsewhere classified
0.711 0.289 0.000
J11 Influenza, virus not identified
0.711 0.289 0.000
J10 Influenza due to identified influenza virus
0.711 0.289 0.000
J14 Pneumonia due to Haemophilus influenzae
0.711 0.289 0.000
J09 Influenza due to certain identified influenza virus
0.711 0.289 0.000
R09.2 Respiratory arrest
0.709 0.291 0.000
D00-D09 In situ neoplasms
0.709 0.291 0.000
C44.4 Skin of scalp and neck
0.709 0.291 0.000
Z03.8 Observation for other suspected diseases and conditions
0.709 0.291 0.000
R49 Voice disturbances
0.708 0.292 0.000
F48 Other neurotic disorders
0.708 0.292 0.000
F45 Somatoform disorders
0.708 0.292 0.000
F44 Dissociative [conversion] disorders
0.708 0.292 0.000
F43 Reaction to severe stress, and adjustment disorders
0.708 0.292 0.000
F42 Obsessive-compulsive disorder
0.708 0.292 0.000
J18.8 Other pneumonia, organism unspecified
0.707 0.293 0.000
J18.2 Hypostatic pneumonia, unspecified
0.707 0.293 0.000
Z03.3 Observation for suspected nervous system disorder
0.706 0.294 0.000
F38 Other mood [affective] disorders
0.705 0.295 0.000
F34 Persistent mood [affective] disorders
0.705 0.295 0.000
F30 Manic episode
0.705 0.295 0.000
F39 Unspecified mood [affective] disorder
0.705 0.295 0.000
J37 Chronic laryngitis and laryngotracheitis
0.705 0.295 0.000
F33 Recurrent depressive disorder
0.705 0.295 0.000
Z97 Presence of other devices
0.705 0.295 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.703 0.296 0.000
F41.8 Other specified anxiety disorders
0.703 0.297 0.000
F41.3 Other mixed anxiety disorders
0.703 0.297 0.000
F41.1 Generalised anxiety disorder
0.703 0.297 0.000
O85-O92 Complications predominantly related to the puerperium
0.702 0.297 0.000
D70 Agranulocytosis
0.702 0.298 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.701 0.299 0.000
Z93.5 Cystostomy status
0.701 0.299 0.000
Z94 Transplanted organ and tissue status
0.701 0.299 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.700 0.300 0.000
E66.8 Other obesity
0.699 0.301 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.699 0.301 0.000
H31 Other disorders of choroid
0.699 0.301 0.000
H30 Chorioretinal inflammation
0.699 0.301 0.000
E40-E46 Malnutrition
0.699 0.301 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.697 0.303 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.697 0.303 0.000
F32.2 Severe depressive episode without psychotic symptoms
0.697 0.303 0.000
O03.9 Complete or unspecified, without complication
0.696 0.304 0.000
F32.8 Other depressive episodes
0.696 0.304 0.000
F32.1 Moderate depressive episode
0.696 0.304 0.000
F32.0 Mild depressive episode
0.696 0.304 0.000
R00.0 Tachycardia, unspecified
0.696 0.304 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.695 0.305 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.694 0.305 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.694 0.305 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.694 0.305 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.694 0.306 0.000
S00-S09 Injuries to the head
0.694 0.306 0.000
B95-B98 Bacterial, viral and other infectious agents
0.694 0.306 0.000
O02 Other abnormal products of conception
0.693 0.307 0.000
F40 Phobic anxiety disorders
0.692 0.308 0.000
R87 Abnormal findings in specimens from female genital organs
0.692 0.308 0.000
Z22.3 Carrier of other specified bacterial diseases
0.691 0.309 0.000
Z37.2 Twins, both liveborn
0.691 0.309 0.000
Z92.0 Personal history of contraception
0.689 0.311 0.000
O42 Premature rupture of membranes
0.687 0.312 0.000
T33-T35 Frostbite
0.687 0.312 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.687 0.312 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.687 0.312 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.687 0.312 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.687 0.312 0.000
T00-T07 Injuries involving multiple body regions
0.687 0.312 0.000
S10-S19 Injuries to the neck
0.687 0.312 0.000
H54.7 Unspecified visual loss
0.687 0.313 0.000
H33.4 Traction detachment of retina
0.687 0.313 0.000
H33.1 Retinoschisis and retinal cysts
0.687 0.313 0.000
H51 Other disorders of binocular movement
0.686 0.314 0.000
H49 Paralytic strabismus
0.686 0.314 0.000
Z01.6 Radiological examination, not elsewhere classified
0.686 0.314 0.000
Z10 Routine general health check-up of defined subpopulation
0.684 0.316 0.000
E11.3 With ophthalmic complications
0.683 0.317 0.000
H40.2 Primary angle-closure glaucoma
0.683 0.317 0.000
H40.1 Primary open-angle glaucoma
0.683 0.317 0.000
H36 Retinal disorders in diseases classified elsewhere
0.683 0.317 0.000
R06.0 Dyspnoea
0.683 0.317 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.682 0.318 0.000
E13 Other specified diabetes mellitus
0.682 0.318 0.000
E12 Malnutrition-related diabetes mellitus
0.682 0.318 0.000
R09.0 Asphyxia
0.682 0.318 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.681 0.319 0.000
I20.1 Angina pectoris with documented spasm
0.680 0.320 0.000
Z34 Supervision of normal pregnancy
0.680 0.320 0.000
T66-T78 Other and unspecified effects of external causes
0.679 0.321 0.000
Z13.9 Special screening examination, unspecified
0.679 0.321 0.000
J95-J99 Other diseases of the respiratory system
0.678 0.322 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.678 0.322 0.000
H40.0 Glaucoma suspect
0.676 0.324 0.000
H35 Other retinal disorders
0.676 0.324 0.000
O48 Prolonged pregnancy
0.675 0.325 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.675 0.325 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.674 0.326 0.000
R82 Other abnormal findings in urine
0.674 0.326 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.673 0.326 0.000
C44.8 Overlapping lesion of skin
0.673 0.326 0.000
C44.0 Skin of lip
0.673 0.326 0.000
Z74 Problems related to care-provider dependency
0.673 0.326 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.673 0.327 0.000
O80-O84 Delivery
0.673 0.327 0.000
Z36 Antenatal screening
0.673 0.327 0.000
R07.1 Chest pain on breathing
0.672 0.328 0.000
K50.9 Crohn's disease, unspecified
0.672 0.328 0.000
J86 Pyothorax
0.671 0.329 0.000
J60-J70 Lung diseases due to external agents
0.671 0.329 0.000
Z50 Care involving use of rehabilitation procedures
0.671 0.329 0.000
O36.5 Maternal care for poor foetal growth
0.670 0.330 0.000
Z35.1 Supervision of pregnancy with history of abortive outcome
0.670 0.330 0.000
C56 Malignant neoplasm of ovary
0.669 0.331 0.000
J35.1 Hypertrophy of tonsils
0.669 0.331 0.000
J36 Peritonsillar abscess
0.668 0.332 0.000
S40-S49 Injuries to the shoulder and upper arm
0.668 0.332 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.667 0.333 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.667 0.333 0.000
E11.4 With neurological complications
0.666 0.334 0.000
E67 Other hyperalimentation
0.666 0.334 0.000
E68 Sequelae of hyperalimentation
0.666 0.334 0.000
E65 Localised adiposity
0.666 0.334 0.000
Z43 Attention to artificial openings
0.665 0.335 0.000
C64-C68 Malignant neoplasms of urinary tract
0.665 0.335 0.000
Z93.1 Gastrostomy status
0.665 0.335 0.000
R06.7 Sneezing
0.664 0.336 0.000
R06.4 Hyperventilation
0.664 0.336 0.000
R06.3 Periodic breathing
0.664 0.336 0.000
R06.2 Wheezing
0.664 0.336 0.000
R06.1 Stridor
0.664 0.336 0.000
Chapter XX External causes of morbidity and mortality
0.663 0.337 0.000
H53.9 Visual disturbance, unspecified
0.660 0.340 0.000
F03 Unspecified dementia
0.660 0.340 0.000
Z39 Postpartum care and examination
0.660 0.340 0.000
E11.8 With unspecified complications
0.659 0.341 0.000
E11.7 With multiple complications
0.659 0.341 0.000
E11.6 With other specified complications
0.659 0.341 0.000
E11.5 With peripheral circulatory complications
0.659 0.341 0.000
E11.2 With renal complications
0.659 0.341 0.000
E11.1 With ketoacidosis
0.659 0.341 0.000
E11.0 With coma
0.659 0.341 0.000
Q50-Q56 Congenital malformations of genital organs
0.659 0.341 0.000
S29 Other and unspecified injuries of thorax
0.659 0.341 0.000
Z38 Liveborn infants according to place of birth
0.658 0.342 0.000
Z32 Pregnancy examination and test
0.658 0.342 0.000
Z31 Procreative management
0.658 0.342 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.658 0.342 0.000
Z03.6 Observation for suspected toxic effect from ingested substance
0.658 0.342 0.000
Z03.2 Observation for suspected mental and behavioural disorders
0.658 0.342 0.000
Z03.0 Observation for suspected tuberculosis
0.658 0.342 0.000
Z73 Problems related to life-management difficulty
0.657 0.343 0.000
R27 Other lack of coordination
0.657 0.343 0.000
H54.4 Blindness, one eye
0.656 0.344 0.000
Chapter VI Diseases of the nervous system
0.656 0.344 0.000
Z01.4 Gynaecological examination (general)(routine)
0.656 0.344 0.000
L20-L30 Dermatitis and eczema
0.655 0.345 0.000
H40.9 Glaucoma, unspecified
0.654 0.346 0.000
J33 Nasal polyp
0.654 0.346 0.000
H52.7 Disorder of refraction, unspecified
0.653 0.347 0.000
H52.6 Other disorders of refraction
0.653 0.347 0.000
H52.5 Disorders of accommodation
0.653 0.347 0.000
H52.4 Presbyopia
0.653 0.347 0.000
H52.3 Anisometropia and aniseikonia
0.653 0.347 0.000
H52.2 Astigmatism
0.653 0.347 0.000
Z84 Family history of other conditions
0.652 0.348 0.000
Z81 Family history of mental and behavioural disorders
0.652 0.348 0.000
Z99.3 Dependence on wheelchair
0.652 0.348 0.000
D73 Diseases of spleen
0.652 0.348 0.000
Chapter VIII Diseases of the ear and mastoid process
0.651 0.349 0.000
S27 Injury of other and unspecified intrathoracic organs
0.651 0.349 0.000
Z99.8 Dependence on other enabling machines and devices
0.650 0.350 0.000
I67 Other cerebrovascular diseases
0.650 0.350 0.000
O36.6 Maternal care for excessive foetal growth
0.650 0.350 0.000
S92 Fracture of foot, except ankle
0.649 0.351 0.000
R01 Cardiac murmurs and other cardiac sounds
0.648 0.351 0.000
D55-D59 Haemolytic anaemias
0.648 0.352 0.000
H42 Glaucoma in diseases classified elsewhere
0.647 0.352 0.000
Z28 Immunisation not carried out
0.647 0.352 0.000
Z27 Need for immunisation against combinations of infectious diseases
0.647 0.352 0.000
Z26 Need for immunisation against other single infectious diseases
0.647 0.352 0.000
Z25 Need for immunisation against other single viral diseases
0.647 0.352 0.000
Z24 Need for immunisation against certain single viral diseases
0.647 0.352 0.000
Z23 Need for immunisation against single bacterial diseases
0.647 0.352 0.000
Z20 Contact with and exposure to communicable diseases
0.647 0.352 0.000
Z21 Asymptomatic human immunodeficiency virus [HIV] infection status
0.647 0.352 0.000
E10 Insulin-dependent diabetes mellitus
0.647 0.353 0.000
O08 Complications following abortion and ectopic and molar pregnancy
0.647 0.353 0.000
O07 Failed attempted abortion
0.647 0.353 0.000
O06 Unspecified abortion
0.647 0.353 0.000
O05 Other abortion
0.647 0.353 0.000
O01 Hydatidiform mole
0.647 0.353 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.645 0.355 0.000
Z95.3 Presence of xenogenic heart valve
0.645 0.355 0.000
T18 Foreign body in alimentary tract
0.645 0.355 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.643 0.357 0.000
H53.8 Other visual disturbances
0.643 0.357 0.000
Z01.8 Other specified special examinations
0.643 0.357 0.000
E66.2 Extreme obesity with alveolar hypoventilation
0.642 0.358 0.000
E66.1 Drug-induced obesity
0.642 0.358 0.000
E66.0 Obesity due to excess calories
0.642 0.358 0.000
I61 Intracerebral haemorrhage
0.642 0.358 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.640 0.360 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.640 0.360 0.000
O45 Premature separation of placenta [abruptio placentae]
0.640 0.360 0.000
O44 Placenta praevia
0.640 0.360 0.000
O43 Placental disorders
0.640 0.360 0.000
O41 Other disorders of amniotic fluid and membranes
0.640 0.360 0.000
O35 Maternal care for known or suspected foetal abnormality and damage
0.640 0.360 0.000
O33 Maternal care for known or suspected disproportion
0.640 0.360 0.000
O31 Complications specific to multiple gestation
0.640 0.360 0.000
O30 Multiple gestation
0.640 0.360 0.000
O40 Polyhydramnios
0.640 0.360 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.640 0.360 0.000
K50.1 Crohn's disease of large intestine
0.639 0.361 0.000
H43 Disorders of vitreous body
0.638 0.361 0.000
O26.8 Other specified pregnancy-related conditions
0.638 0.362 0.000
B35-B49 Mycoses
0.638 0.362 0.000
H50.1 Divergent concomitant strabismus
0.637 0.363 0.000
S50-S59 Injuries to the elbow and forearm
0.636 0.364 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.635 0.365 0.000
I95 Hypotension
0.635 0.365 0.000
O46.9 Antepartum haemorrhage, unspecified
0.634 0.365 0.000
Z93.6 Other artificial openings of urinary tract status
0.634 0.366 0.000
Z03.1 Observation for suspected malignant neoplasm
0.634 0.366 0.000
Z02 Examination and encounter for administrative purposes
0.633 0.367 0.000
C80 Malignant neoplasm without specification of site
0.632 0.367 0.000
K70-K77 Diseases of liver
0.632 0.368 0.000
Z35.5 Supervision of elderly primigravida
0.632 0.368 0.000
L50-L54 Urticaria and erythema
0.632 0.368 0.000
E53 Deficiency of other B group vitamins
0.631 0.369 0.000
L03.1 Cellulitis of other parts of limb
0.631 0.369 0.000
J00-J06 Acute upper respiratory infections
0.631 0.369 0.000
O32 Maternal care for known or suspected malpresentation of foetus
0.631 0.369 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.630 0.370 0.000
J91 Pleural effusion in conditions classified elsewhere
0.630 0.370 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.630 0.370 0.000
S20 Superficial injury of thorax
0.628 0.371 0.000
Z35.2 Supervision of pregnancy with other poor reproductive or obstetric history
0.628 0.372 0.000
R25.2 Cramp and spasm
0.626 0.374 0.000
O47 False labour
0.626 0.374 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.626 0.374 0.000
Z04 Examination and observation for other reasons
0.625 0.374 0.000
Z33 Pregnant state, incidental
0.625 0.375 0.000
C77.0 Lymph nodes of head, face and neck
0.624 0.376 0.000
R81 Glycosuria
0.624 0.376 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.623 0.377 0.000
Z92.9 Personal history of medical treatment, unspecified
0.621 0.378 0.000
Z92.8 Personal history of other medical treatment
0.621 0.378 0.000
Z92.5 Personal history of rehabilitation measures
0.621 0.378 0.000
R39.1 Other difficulties with micturition
0.621 0.379 0.000
S82.1 Fracture of upper end of tibia
0.620 0.380 0.000
H53.6 Night blindness
0.618 0.381 0.000
H53.5 Colour vision deficiencies
0.618 0.381 0.000
H53.3 Other disorders of binocular vision
0.618 0.381 0.000
R49.0 Dysphonia
0.618 0.382 0.000
Z29.0 Isolation
0.618 0.382 0.000
R33 Retention of urine
0.618 0.382 0.000
R21 Rash and other nonspecific skin eruption
0.617 0.383 0.000
T17 Foreign body in respiratory tract
0.617 0.383 0.000
Z37.9 Outcome of delivery unspecified
0.616 0.383 0.000
Z37.7 Other multiple births, all stillborn
0.616 0.383 0.000
Z37.6 Other multiple births, some liveborn
0.616 0.383 0.000
Z37.5 Other multiple births, all liveborn
0.616 0.383 0.000
Z37.4 Twins, both stillborn
0.616 0.383 0.000
Z37.3 Twins, one liveborn and one stillborn
0.616 0.383 0.000
Z37.1 Single stillbirth
0.616 0.383 0.000
H57 Other disorders of eye and adnexa
0.616 0.384 0.000
L02.2 Cutaneous abscess, furuncle and carbuncle of trunk
0.616 0.384 0.000
F41.2 Mixed anxiety and depressive disorder
0.616 0.384 0.000
I63 Cerebral infarction
0.615 0.385 0.000
C20 Malignant neoplasm of rectum
0.615 0.385 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.614 0.386 0.000
R09.3 Abnormal sputum
0.614 0.386 0.000
C71 Malignant neoplasm of brain
0.614 0.386 0.000
J39 Other diseases of upper respiratory tract
0.614 0.386 0.000
J94 Other pleural conditions
0.613 0.386 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.612 0.388 0.000
Q80-Q89 Other congenital malformations
0.612 0.388 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.612 0.388 0.000
Q60-Q64 Congenital malformations of the urinary system
0.612 0.388 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.612 0.388 0.000
Q35-Q37 Cleft lip and cleft palate
0.612 0.388 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.612 0.388 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.612 0.388 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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