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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs143136847
log Bayes Factor = 1.54314
Chromosome 12   position 82,748,339  (GRCh37) Explore rs143136847 on Ensembl!
Variant rs143136847 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.967 0.033 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.957 0.043 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.947 0.053 0.000
Chapter XIV Diseases of the genitourinary system
0.935 0.065 0.000
Chapter VI Diseases of the nervous system
0.934 0.066 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.916 0.084 0.000
E70-E90 Metabolic disorders
0.916 0.084 0.000
G56 Mononeuropathies of upper limb
0.909 0.091 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.908 0.092 0.000
G56.0 Carpal tunnel syndrome
0.902 0.098 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.891 0.109 0.000
E86 Volume depletion
0.889 0.111 0.000
S80-S89 Injuries to the knee and lower leg
0.878 0.122 0.000
Chapter II Neoplasms
0.867 0.133 0.000
M05-M14 Inflammatory polyarthropathies
0.864 0.136 0.000
Chapter VIII Diseases of the ear and mastoid process
0.860 0.140 0.000
Chapter XX External causes of morbidity and mortality
0.849 0.150 0.000
D10-D36 Benign neoplasms
0.849 0.151 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.842 0.158 0.000
S00-S09 Injuries to the head
0.834 0.166 0.000
S82 Fracture of lower leg, including ankle
0.830 0.170 0.000
M13 Other arthritis
0.827 0.173 0.000
M45-M49 Spondylopathies
0.813 0.187 0.000
D17 Benign lipomatous neoplasm
0.806 0.194 0.000
N20-N23 Urolithiasis
0.805 0.195 0.000
M13.9 Arthritis, unspecified
0.800 0.200 0.000
Chapter VII Diseases of the eye and adnexa
0.800 0.200 0.000
N10-N16 Renal tubulo-interstitial diseases
0.796 0.204 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.795 0.205 0.000
E10-E14 Diabetes mellitus
0.792 0.208 0.000
N25-N29 Other disorders of kidney and ureter
0.792 0.208 0.000
D22 Melanocytic naevi
0.789 0.211 0.000
N85.8 Other specified noninflammatory disorders of uterus
0.785 0.215 0.000
E00-E07 Disorders of thyroid gland
0.784 0.216 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.783 0.216 0.000
E20-E35 Disorders of other endocrine glands
0.771 0.229 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.755 0.245 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.754 0.246 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.749 0.251 0.000
M13.94 Arthritis, unspecified (Hand)
0.747 0.253 0.000
S20-S29 Injuries to the thorax
0.746 0.254 0.000
S01 Open wound of head
0.744 0.256 0.000
N87 Dysplasia of cervix uteri
0.740 0.260 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.739 0.261 0.000
E65-E68 Obesity and other hyperalimentation
0.735 0.265 0.000
H90-H95 Other disorders of ear
0.734 0.266 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.732 0.268 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.730 0.270 0.000
S50-S59 Injuries to the elbow and forearm
0.730 0.270 0.000
N20 Calculus of kidney and ureter
0.728 0.272 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.727 0.273 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.722 0.278 0.000
D22.5 Melanocytic naevi of trunk
0.722 0.278 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.720 0.280 0.000
G56.2 Lesion of ulnar nerve
0.720 0.280 0.000
S82.6 Fracture of lateral malleolus
0.719 0.281 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.718 0.282 0.000
Chapter V Mental and behavioural disorders
0.714 0.286 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.713 0.287 0.000
E50-E64 Other nutritional deficiencies
0.713 0.287 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.713 0.287 0.000
H02 Other disorders of eyelid
0.712 0.288 0.000
N81 Female genital prolapse
0.712 0.288 0.000
N00-N08 Glomerular diseases
0.710 0.290 0.000
M47 Spondylosis
0.709 0.291 0.000
N85.2 Hypertrophy of uterus
0.709 0.291 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.706 0.294 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.700 0.300 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.700 0.300 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.700 0.300 0.000
S40-S49 Injuries to the shoulder and upper arm
0.698 0.301 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.698 0.302 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.697 0.303 0.000
D18 Haemangioma and lymphangioma, any site
0.696 0.304 0.000
Chapter XXII Codes for special purposes
0.693 0.307 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.693 0.307 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.691 0.309 0.000
S82.8 Fractures of other parts of lower leg
0.690 0.310 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.690 0.310 0.000
N95 Menopausal and other perimenopausal disorders
0.689 0.311 0.000
E40-E46 Malnutrition
0.686 0.314 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.686 0.314 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.683 0.317 0.000
G30-G32 Other degenerative diseases of the nervous system
0.682 0.318 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.679 0.321 0.000
T79-T79 Certain early complications of trauma
0.679 0.321 0.000
T66-T78 Other and unspecified effects of external causes
0.679 0.321 0.000
T33-T35 Frostbite
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.679 0.321 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.679 0.321 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.679 0.321 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.679 0.321 0.000
T00-T07 Injuries involving multiple body regions
0.679 0.321 0.000
S90-S99 Injuries to the ankle and foot
0.679 0.321 0.000
S10-S19 Injuries to the neck
0.679 0.321 0.000
G20-G26 Extrapyramidal and movement disorders
0.678 0.322 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.678 0.322 0.000
R30-R39 Symptoms and signs involving the urinary system
0.678 0.322 0.000
M40-M43 Deforming dorsopathies
0.675 0.324 0.000
S00 Superficial injury of head
0.675 0.325 0.000
M50-M54 Other dorsopathies
0.673 0.327 0.000
M06 Other rheumatoid arthritis
0.672 0.328 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.671 0.329 0.000
N99-N99 Other disorders of the genitourinary system
0.670 0.330 0.000
E10 Insulin-dependent diabetes mellitus
0.670 0.330 0.000
G70-G73 Diseases of myoneural junction and muscle
0.669 0.330 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.669 0.330 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.669 0.330 0.000
C51-C58 Malignant neoplasms of female genital organs
0.669 0.331 0.000
N13 Obstructive and reflux uropathy
0.668 0.332 0.000
N80 Endometriosis
0.665 0.335 0.000
S82.2 Fracture of shaft of tibia
0.665 0.335 0.000
E83 Disorders of mineral metabolism
0.664 0.336 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.664 0.336 0.000
M48 Other spondylopathies
0.662 0.338 0.000
D34 Benign neoplasm of thyroid gland
0.661 0.339 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.660 0.340 0.000
S70-S79 Injuries to the hip and thigh
0.658 0.342 0.000
H80-H83 Diseases of inner ear
0.657 0.342 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.657 0.343 0.000
G58 Other mononeuropathies
0.657 0.343 0.000
G54 Nerve root and plexus disorders
0.657 0.343 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.657 0.343 0.000
G52 Disorders of other cranial nerves
0.657 0.343 0.000
G50 Disorders of trigeminal nerve
0.657 0.343 0.000
G55 Nerve root and plexus compressions in diseases classified elsewhere
0.657 0.343 0.000
E88 Other metabolic disorders
0.656 0.343 0.000
E85 Amyloidosis
0.656 0.343 0.000
E84 Cystic fibrosis
0.656 0.343 0.000
E79 Disorders of purine and pyrimidine metabolism
0.656 0.343 0.000
E77 Disorders of glycoprotein metabolism
0.656 0.343 0.000
E76 Disorders of glycosaminoglycan metabolism
0.656 0.343 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.656 0.343 0.000
E74 Other disorders of carbohydrate metabolism
0.656 0.343 0.000
E73 Lactose intolerance
0.656 0.343 0.000
E72 Other disorders of amino-acid metabolism
0.656 0.343 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.656 0.343 0.000
E70 Disorders of aromatic amino-acid metabolism
0.656 0.343 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.656 0.343 0.000
N89 Other noninflammatory disorders of vagina
0.656 0.344 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.654 0.346 0.000
H65-H75 Diseases of middle ear and mastoid
0.653 0.347 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.653 0.347 0.000
G56.9 Mononeuropathy of upper limb, unspecified
0.652 0.348 0.000
G56.8 Other mononeuropathies of upper limb
0.652 0.348 0.000
G56.4 Causalgia
0.652 0.348 0.000
G56.3 Lesion of radial nerve
0.652 0.348 0.000
G56.1 Other lesions of median nerve
0.652 0.348 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.651 0.349 0.000
M91-M94 Chondropathies
0.651 0.349 0.000
M86-M90 Other osteopathies
0.651 0.349 0.000
M60-M63 Disorders of muscles
0.651 0.349 0.000
M00-M03 Infectious arthropathies
0.651 0.349 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.649 0.351 0.000
H60-H62 Diseases of external ear
0.648 0.352 0.000
R33 Retention of urine
0.647 0.353 0.000
W20-W49 Exposure to inanimate mechanical forces
0.646 0.354 0.000
N20.0 Calculus of kidney
0.646 0.354 0.000
Chapter I Certain infectious and parasitic diseases
0.644 0.356 0.000
S82.4 Fracture of fibula alone
0.643 0.357 0.000
N85.0 Endometrial glandular hyperplasia
0.643 0.357 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.642 0.357 0.000
D22.1 Melanocytic naevi of eyelid, including canthus
0.641 0.359 0.000
E04 Other non-toxic goitre
0.640 0.360 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.640 0.360 0.000
N76 Other inflammation of vagina and vulva
0.640 0.360 0.000
G51 Facial nerve disorders
0.640 0.360 0.000
S82.60 Fracture of lateral malleolus (closed)
0.639 0.361 0.000
N98 Complications associated with artificial fertilisation
0.639 0.361 0.000
N91 Absent, scanty and rare menstruation
0.639 0.361 0.000
N82 Fistulae involving female genital tract
0.639 0.361 0.000
N96 Habitual aborter
0.639 0.361 0.000
M80-M85 Disorders of bone density and structure
0.638 0.362 0.000
G40-G47 Episodic and paroxysmal disorders
0.638 0.362 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.637 0.363 0.000
N83.2 Other and unspecified ovarian cysts
0.636 0.364 0.000
S60-S69 Injuries to the wrist and hand
0.635 0.365 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.634 0.366 0.000
F30-F39 Mood [affective] disorders
0.633 0.367 0.000
H53-H54 Visual disturbances and blindness
0.632 0.368 0.000
H04 Disorders of lachrymal system
0.632 0.368 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.631 0.369 0.000
N87.0 Mild cervical dysplasia
0.631 0.369 0.000
S89 Other and unspecified injuries of lower leg
0.629 0.371 0.000
S88 Traumatic amputation of lower leg
0.629 0.371 0.000
S87 Crushing injury of lower leg
0.629 0.371 0.000
S86 Injury of muscle and tendon at lower leg level
0.629 0.371 0.000
S85 Injury of blood vessels at lower leg level
0.629 0.371 0.000
S84 Injury of nerves at lower leg level
0.629 0.371 0.000
S81 Open wound of lower leg
0.629 0.371 0.000
S80 Superficial injury of lower leg
0.629 0.371 0.000
M13.95 Arthritis, unspecified (Pelvic region and thigh)
0.628 0.372 0.000
H91 Other hearing loss
0.628 0.372 0.000
H02.8 Other specified disorders of eyelid
0.626 0.374 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.626 0.374 0.000
S01.5 Open wound of lip and oral cavity
0.625 0.375 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.622 0.378 0.000
D00-D09 In situ neoplasms
0.622 0.378 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.621 0.378 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.621 0.378 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.621 0.378 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.621 0.378 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.621 0.378 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.621 0.378 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.621 0.379 0.000
S02 Fracture of skull and facial bones
0.621 0.379 0.000
G90-G99 Other disorders of the nervous system
0.620 0.379 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.620 0.379 0.000
M14 Arthropathies in other diseases classified elsewhere
0.620 0.380 0.000
M12 Other specific arthropathies
0.620 0.380 0.000
M11 Other crystal arthropathies
0.620 0.380 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.620 0.380 0.000
M08 Juvenile arthritis
0.620 0.380 0.000
M07 Psoriatic and enteropathic arthropathies
0.620 0.380 0.000
M05 Seropositive rheumatoid arthritis
0.620 0.380 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.619 0.380 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.619 0.381 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.618 0.382 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.618 0.382 0.000
R47-R49 Symptoms and signs involving speech and voice
0.617 0.383 0.000
D11 Benign neoplasm of major salivary glands
0.617 0.383 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.616 0.383 0.000
S82.1 Fracture of upper end of tibia
0.616 0.384 0.000
V10-V19 Pedal cyclist injured in transport accident
0.616 0.384 0.000
N88 Other noninflammatory disorders of cervix uteri
0.615 0.385 0.000
D23 Other benign neoplasms of skin
0.615 0.385 0.000
N40-N51 Diseases of male genital organs
0.615 0.385 0.000
C43 Malignant melanoma of skin
0.615 0.385 0.000
N72 Inflammatory disease of cervix uteri
0.615 0.385 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.614 0.386 0.000
W00-W19 Falls
0.614 0.386 0.000
N94.6 Dysmenorrhoea, unspecified
0.613 0.387 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.609 0.391 0.000
Y35-Y36 Legal intervention and operations of war
0.609 0.391 0.000
Y10-Y34 Event of undetermined intent
0.609 0.391 0.000
Y00-Y09 Assault
0.609 0.391 0.000
X85-X99 Assault
0.609 0.391 0.000
X60-X84 Intentional self-harm
0.609 0.391 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.609 0.391 0.000
X50-X57 Overexertion, travel and privation
0.609 0.391 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.609 0.391 0.000
X30-X39 Exposure to forces of nature
0.609 0.391 0.000
X20-X29 Contact with venomous animals and plants
0.609 0.391 0.000
X10-X19 Contact with heat and hot substances
0.609 0.391 0.000
X00-X09 Exposure to smoke, fire and flames
0.609 0.391 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.609 0.391 0.000
W75-W84 Other accidental threats to breathing
0.609 0.391 0.000
W65-W74 Accidental drowning and submersion
0.609 0.391 0.000
W50-W64 Exposure to animate mechanical forces
0.609 0.391 0.000
V98-V99 Other and unspecified transport accidents
0.609 0.391 0.000
V95-V97 Air and space transport accidents
0.609 0.391 0.000
V90-V94 Water transport accidents
0.609 0.391 0.000
V80-V89 Other land transport accidents
0.609 0.391 0.000
V70-V79 Bus occupant injured in transport accident
0.609 0.391 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.609 0.391 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.609 0.391 0.000
V40-V49 Car occupant injured in transport accident
0.609 0.391 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.609 0.391 0.000
V20-V29 Motorcycle rider injured in transport accident
0.609 0.391 0.000
V01-V09 Pedestrian injured in transport accident
0.609 0.391 0.000
N84 Polyp of female genital tract
0.609 0.391 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.609 0.391 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.609 0.391 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.608 0.391 0.000
D32 Benign neoplasm of meninges
0.608 0.391 0.000
D31 Benign neoplasm of eye and adnexa
0.608 0.391 0.000
D30 Benign neoplasm of urinary organs
0.608 0.391 0.000
D29 Benign neoplasm of male genital organs
0.608 0.391 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.608 0.391 0.000
D26 Other benign neoplasms of uterus
0.608 0.391 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.608 0.391 0.000
D19 Benign neoplasm of mesothelial tissue
0.608 0.391 0.000
D16 Benign neoplasm of bone and articular cartilage
0.608 0.391 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.608 0.391 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.608 0.391 0.000
D10 Benign neoplasm of mouth and pharynx
0.608 0.391 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.608 0.392 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.607 0.393 0.000
D24 Benign neoplasm of breast
0.607 0.393 0.000
M20-M25 Other joint disorders
0.606 0.394 0.000
N85.9 Noninflammatory disorder of uterus, unspecified
0.604 0.396 0.000
N85.7 Haematometra
0.604 0.396 0.000
N85.6 Intra-uterine synechiae
0.604 0.396 0.000
N85.5 Inversion of uterus
0.604 0.396 0.000
N85.3 Subinvolution of uterus
0.604 0.396 0.000
N85.1 Endometrial adenomatous hyperplasia
0.604 0.396 0.000
H43-H45 Disorders of vitreous body and globe
0.604 0.396 0.000
M10 Gout
0.603 0.397 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.602 0.398 0.000
E07 Other disorders of thyroid
0.600 0.400 0.000
S08 Traumatic amputation of part of head
0.598 0.402 0.000
S07 Crushing injury of head
0.598 0.402 0.000
S06 Intracranial injury
0.598 0.402 0.000
S05 Injury of eye and orbit
0.598 0.402 0.000
S04 Injury of cranial nerves
0.598 0.402 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.598 0.402 0.000
R94 Abnormal results of function studies
0.598 0.402 0.000
M65-M68 Disorders of synovium and tendon
0.597 0.402 0.000
S82.9 Fracture of lower leg, part unspecified
0.595 0.405 0.000
S82.7 Multiple fractures of lower leg
0.595 0.405 0.000
S82.5 Fracture of medial malleolus
0.595 0.405 0.000
S82.3 Fracture of lower end of tibia
0.595 0.405 0.000
S82.0 Fracture of patella
0.595 0.405 0.000
S01.2 Open wound of nose
0.594 0.406 0.000
E87.7 Fluid overload
0.593 0.407 0.000
M13.8 Other specified arthritis
0.593 0.407 0.000
M13.1 Monoarthritis, not elsewhere classified
0.593 0.407 0.000
M13.0 Polyarthritis, unspecified
0.593 0.407 0.000
D22.6 Melanocytic naevi of upper limb, including shoulder
0.592 0.408 0.000
M47.9 Spondylosis, unspecified
0.592 0.408 0.000
N90.7 Vulvar cyst
0.591 0.409 0.000
M13.90 Arthritis, unspecified (Multiple sites)
0.591 0.409 0.000
Y83 Surgical operation and other surgical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.591 0.409 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.591 0.409 0.000
N20.1 Calculus of ureter
0.590 0.410 0.000
S82.80 Fractures of other parts of lower leg (closed)
0.589 0.411 0.000
N28.1 Cyst of kidney, acquired
0.589 0.411 0.000
E11 Non-insulin-dependent diabetes mellitus
0.588 0.412 0.000
N80.0 Endometriosis of uterus
0.588 0.412 0.000
D18.0 Haemangioma, any site
0.587 0.413 0.000
R21 Rash and other nonspecific skin eruption
0.587 0.413 0.000
G35 Multiple sclerosis
0.587 0.413 0.000
S01.9 Open wound of head, part unspecified
0.586 0.414 0.000
D36 Benign neoplasm of other and unspecified sites
0.585 0.415 0.000
H02.5 Other disorders affecting eyelid function
0.584 0.416 0.000
E80.4 Gilbert's syndrome
0.583 0.417 0.000
M49 Spondylopathies in diseases classified elsewhere
0.583 0.417 0.000
M46 Other inflammatory spondylopathies
0.583 0.417 0.000
M45 Ankylosing spondylitis
0.583 0.417 0.000
M47.8 Other spondylosis
0.583 0.417 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.582 0.418 0.000
N81.1 Cystocele
0.582 0.418 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.580 0.420 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.579 0.421 0.000
E10.9 Without complications
0.579 0.421 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.579 0.421 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.578 0.422 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.578 0.422 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.578 0.422 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.578 0.422 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.578 0.422 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.577 0.423 0.000
R31 Unspecified haematuria
0.577 0.423 0.000
E66 Obesity
0.576 0.424 0.000
Y40 Systemic antibiotics
0.575 0.425 0.000
S52 Fracture of forearm
0.574 0.426 0.000
M13.98 Arthritis, unspecified (Other)
0.574 0.426 0.000
M13.93 Arthritis, unspecified (Forearm)
0.574 0.426 0.000
M13.92 Arthritis, unspecified (Upper arm)
0.574 0.426 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.574 0.426 0.000
H55-H59 Other disorders of eye and adnexa
0.574 0.426 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.574 0.426 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.574 0.426 0.000
H10-H13 Disorders of conjunctiva
0.574 0.426 0.000
S00.9 Superficial injury of head, part unspecified
0.574 0.426 0.000
M15-M19 Arthrosis
0.573 0.427 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.571 0.429 0.000
N15 Other renal tubulo-interstitial diseases
0.571 0.429 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.571 0.429 0.000
N11 Chronic tubulo-interstitial nephritis
0.571 0.429 0.000
N10 Acute tubulo-interstitial nephritis
0.571 0.429 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.570 0.429 0.000
Y43 Primarily systemic agents
0.570 0.430 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.570 0.430 0.000
M50 Cervical disk disorders
0.570 0.430 0.000
H02.1 Ectropion of eyelid
0.569 0.431 0.000
T18 Foreign body in alimentary tract
0.569 0.431 0.000
E87.5 Hyperkalaemia
0.568 0.432 0.000
E13 Other specified diabetes mellitus
0.568 0.432 0.000
E12 Malnutrition-related diabetes mellitus
0.568 0.432 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.568 0.432 0.000
N27 Small kidney of unknown cause
0.568 0.432 0.000
N25 Disorders resulting from impaired renal tubular function
0.568 0.432 0.000
N26 Unspecified contracted kidney
0.568 0.432 0.000
N75 Diseases of Bartholin's gland
0.567 0.433 0.000
N60-N64 Disorders of breast
0.566 0.434 0.000
D22.9 Melanocytic naevi, unspecified
0.566 0.434 0.000
D22.4 Melanocytic naevi of scalp and neck
0.566 0.434 0.000
D22.2 Melanocytic naevi of ear and external auricular canal
0.566 0.434 0.000
D22.0 Melanocytic naevi of lip
0.566 0.434 0.000
H02.4 Ptosis of eyelid
0.566 0.434 0.000
N02 Recurrent and persistent haematuria
0.565 0.435 0.000
N13.3 Other and unspecified hydronephrosis
0.563 0.437 0.000
E06 Thyroiditis
0.562 0.438 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.562 0.438 0.000
E00 Congenital iodine-deficiency syndrome
0.562 0.438 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.562 0.438 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.562 0.438 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.562 0.438 0.000
N71 Inflammatory disease of uterus, except cervix
0.562 0.438 0.000
N70 Salpingitis and oophoritis
0.562 0.438 0.000
N81.9 Female genital prolapse, unspecified
0.558 0.442 0.000
N73 Other female pelvic inflammatory diseases
0.558 0.442 0.000
N23 Unspecified renal colic
0.557 0.442 0.000
H93 Other disorders of ear, not elsewhere classified
0.557 0.443 0.000
D35.1 Parathyroid gland
0.556 0.444 0.000
E14 Unspecified diabetes mellitus
0.555 0.444 0.000
D46 Myelodysplastic syndromes
0.554 0.445 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.554 0.446 0.000
M48.0 Spinal stenosis
0.554 0.446 0.000
R00 Abnormalities of heart beat
0.553 0.447 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.553 0.447 0.000
E34 Other endocrine disorders
0.553 0.447 0.000
E32 Diseases of thymus
0.553 0.447 0.000
E31 Polyglandular dysfunction
0.553 0.447 0.000
E30 Disorders of puberty, not elsewhere classified
0.553 0.447 0.000
E29 Testicular dysfunction
0.553 0.447 0.000
E28 Ovarian dysfunction
0.553 0.447 0.000
E27 Other disorders of adrenal gland
0.553 0.447 0.000
E26 Hyperaldosteronism
0.553 0.447 0.000
E25 Adrenogenital disorders
0.553 0.447 0.000
E24 Cushing's syndrome
0.553 0.447 0.000
E23 Hypofunction and other disorders of pituitary gland
0.553 0.447 0.000
E22 Hyperfunction of pituitary gland
0.553 0.447 0.000
E20 Hypoparathyroidism
0.553 0.447 0.000
H91.9 Hearing loss, unspecified
0.552 0.448 0.000
N21 Calculus of lower urinary tract
0.551 0.449 0.000
R94.5 Abnormal results of liver function studies
0.550 0.450 0.000
G40 Epilepsy
0.549 0.451 0.000
R29.6 Tendency to fall, not elsewhere classified
0.549 0.451 0.000
N95.0 Postmenopausal bleeding
0.548 0.452 0.000
N28.8 Other specified disorders of kidney and ureter
0.548 0.452 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.546 0.454 0.000
S82.20 Fracture of shaft of tibia (closed)
0.546 0.454 0.000
N81.4 Uterovaginal prolapse, unspecified
0.545 0.455 0.000
S32 Fracture of lumbar spine and pelvis
0.545 0.455 0.000
S01.0 Open wound of scalp
0.545 0.455 0.000
N81.8 Other female genital prolapse
0.544 0.456 0.000
D21.2 Connective and other soft tissue of lower limb, including hip
0.543 0.456 0.000
G57 Mononeuropathies of lower limb
0.543 0.457 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.542 0.457 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.541 0.459 0.000
H05 Disorders of orbit
0.541 0.459 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.541 0.459 0.000
H01 Other inflammation of eyelid
0.541 0.459 0.000
D80-D89 Certain disorders involving the immune mechanism
0.541 0.459 0.000
D55-D59 Haemolytic anaemias
0.541 0.459 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.540 0.460 0.000
Y83.8 Other surgical procedures
0.540 0.460 0.000
N97 Female infertility
0.538 0.462 0.000
E55 Vitamin D deficiency
0.538 0.462 0.000
N94.1 Dyspareunia
0.538 0.462 0.000
E87.8 Other disorders of electrolyte and fluid balance, not elsewhere classified
0.537 0.463 0.000
E87.4 Mixed disorder of acid-base balance
0.537 0.463 0.000
E87.3 Alkalosis
0.537 0.463 0.000
E87.0 Hyperosmolality and hypernatraemia
0.537 0.463 0.000
N76.2 Acute vulvitis
0.537 0.463 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.537 0.463 0.000
S29 Other and unspecified injuries of thorax
0.535 0.465 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.535 0.465 0.000
S27 Injury of other and unspecified intrathoracic organs
0.535 0.465 0.000
S26 Injury of heart
0.535 0.465 0.000
S25 Injury of blood vessels of thorax
0.535 0.465 0.000
S24 Injury of nerves and spinal cord at thorax level
0.535 0.465 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.535 0.465 0.000
S21 Open wound of thorax
0.535 0.465 0.000
S20 Superficial injury of thorax
0.535 0.465 0.000
N85.4 Malposition of uterus
0.535 0.465 0.000
H02.3 Blepharochalasis
0.535 0.465 0.000
M06.9 Rheumatoid arthritis, unspecified
0.534 0.465 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.533 0.466 0.000
N87.1 Moderate cervical dysplasia
0.533 0.466 0.000
S01.7 Multiple open wounds of head
0.533 0.467 0.000
S01.4 Open wound of cheek and temporomandibular area
0.533 0.467 0.000
S01.3 Open wound of ear
0.533 0.467 0.000
S01.1 Open wound of eyelid and periocular area
0.533 0.467 0.000
C50-C50 Malignant neoplasm of breast
0.533 0.467 0.000
E04.9 Non-toxic goitre, unspecified
0.533 0.467 0.000
C56 Malignant neoplasm of ovary
0.532 0.468 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.532 0.468 0.000
D45 Polycythaemia vera
0.532 0.468 0.000
F32 Depressive episode
0.531 0.469 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.531 0.469 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.531 0.469 0.000
Y59 Other and unspecified vaccines and biological substances
0.530 0.470 0.000
Y58 Bacterial vaccines
0.530 0.470 0.000
Y57 Other and unspecified drugs and medicaments
0.530 0.470 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.530 0.470 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.530 0.470 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.530 0.470 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.530 0.470 0.000
Y52 Agents primarily affecting the cardiovascular system
0.530 0.470 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.530 0.470 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.530 0.470 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.530 0.470 0.000
Y48 Anaesthetics and therapeutic gases
0.530 0.470 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.530 0.470 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.530 0.470 0.000
Y44 Agents primarily affecting blood constituents
0.530 0.470 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.530 0.470 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.530 0.470 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.529 0.470 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.529 0.471 0.000
R29.8 Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
0.528 0.472 0.000
H04.5 Stenosis and insufficiency of lachrymal passages
0.527 0.472 0.000
E67 Other hyperalimentation
0.527 0.473 0.000
E68 Sequelae of hyperalimentation
0.527 0.473 0.000
E65 Localised adiposity
0.527 0.473 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.526 0.474 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.526 0.474 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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