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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs143192258
log Bayes Factor = 18.3741
Chromosome 11   position 56,954,985  (GRCh37) Explore rs143192258 on Ensembl!
Variant rs143192258 is part of Cluster X0069

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
1.000 0.000 0.000
Z86 Personal history of certain other diseases
1.000 0.000 0.000
Z86.7 Personal history of diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
I60-I69 Cerebrovascular diseases
0.999 0.001 0.000
Z92.1 Personal history of long-term (current) use of anticoagulants
0.999 0.001 0.000
I21 Acute myocardial infarction
0.999 0.001 0.000
I25.1 Atherosclerotic heart disease
0.999 0.001 0.000
Z92 Personal history of medical treatment
0.999 0.001 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter X Diseases of the respiratory system
0.998 0.002 0.000
I63 Cerebral infarction
0.992 0.008 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.990 0.010 0.000
I63.9 Cerebral infarction, unspecified
0.987 0.013 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.979 0.021 0.000
S60-S69 Injuries to the wrist and hand
0.979 0.021 0.000
S00-S09 Injuries to the head
0.977 0.023 0.000
I21.9 Acute myocardial infarction, unspecified
0.976 0.024 0.000
J30-J39 Other diseases of upper respiratory tract
0.966 0.034 0.000
Z82.4 Family history of ischaemic heart disease and other diseases of the circulatory system
0.962 0.038 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.959 0.041 0.000
Chapter XX External causes of morbidity and mortality
0.958 0.042 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.958 0.042 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.955 0.045 0.000
J40-J47 Chronic lower respiratory diseases
0.953 0.047 0.000
Z86.5 Personal history of other mental and behavioural disorders
0.951 0.049 0.000
J45 Asthma
0.949 0.051 0.000
I20 Angina pectoris
0.948 0.052 0.000
J45.9 Asthma, unspecified
0.941 0.059 0.000
J34 Other disorders of nose and nasal sinuses
0.938 0.062 0.000
S80-S89 Injuries to the knee and lower leg
0.934 0.066 0.000
I67 Other cerebrovascular diseases
0.932 0.068 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.927 0.073 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.926 0.074 0.000
I21.4 Acute subendocardial myocardial infarction
0.926 0.074 0.000
M70-M79 Other soft tissue disorders
0.923 0.077 0.000
I26 Pulmonary embolism
0.921 0.079 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.919 0.081 0.000
M45-M49 Spondylopathies
0.918 0.082 0.000
J00-J06 Acute upper respiratory infections
0.910 0.090 0.000
I20.0 Unstable angina
0.906 0.094 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.905 0.095 0.000
Chapter I Certain infectious and parasitic diseases
0.903 0.097 0.000
I26.9 Pulmonary embolism without mention of acute cor pulmonale
0.898 0.102 0.000
I25.2 Old myocardial infarction
0.898 0.102 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.895 0.105 0.000
S02 Fracture of skull and facial bones
0.892 0.108 0.000
J34.2 Deviated nasal septum
0.891 0.109 0.000
M40-M43 Deforming dorsopathies
0.890 0.110 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.885 0.115 0.000
M48 Other spondylopathies
0.884 0.116 0.000
S90-S99 Injuries to the ankle and foot
0.883 0.117 0.000
I24 Other acute ischaemic heart diseases
0.877 0.123 0.000
I60 Subarachnoid haemorrhage
0.875 0.125 0.000
S80 Superficial injury of lower leg
0.871 0.129 0.000
M20-M25 Other joint disorders
0.871 0.129 0.000
Z95.0 Presence of cardiac pacemaker
0.871 0.129 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.866 0.134 0.000
S09 Other and unspecified injuries of head
0.861 0.139 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.861 0.139 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.860 0.140 0.000
M48.0 Spinal stenosis
0.859 0.141 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.859 0.141 0.000
M23 Internal derangement of knee
0.858 0.142 0.000
J09-J18 Influenza and pneumonia
0.858 0.142 0.000
Z86.4 Personal history of psychoactive substance abuse
0.857 0.143 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.855 0.145 0.000
S06 Intracranial injury
0.855 0.145 0.000
M05-M14 Inflammatory polyarthropathies
0.853 0.147 0.000
S62 Fracture at wrist and hand level
0.850 0.150 0.000
I67.9 Cerebrovascular disease, unspecified
0.847 0.153 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.844 0.156 0.000
Chapter II Neoplasms
0.840 0.160 0.000
S50-S59 Injuries to the elbow and forearm
0.840 0.160 0.000
S61 Open wound of wrist and hand
0.839 0.161 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.839 0.161 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.838 0.162 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.836 0.164 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.834 0.166 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.831 0.169 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.830 0.170 0.000
J45.0 Predominantly allergic asthma
0.822 0.178 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.817 0.183 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.815 0.185 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.815 0.185 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.814 0.186 0.000
M48.06 Spinal stenosis (Lumbar region)
0.813 0.187 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.811 0.189 0.000
B25-B34 Other viral diseases
0.811 0.189 0.000
I69 Sequelae of cerebrovascular disease
0.807 0.193 0.000
Y43 Primarily systemic agents
0.805 0.195 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.804 0.196 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.803 0.197 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.800 0.200 0.000
D68 Other coagulation defects
0.799 0.201 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.798 0.202 0.000
S60 Superficial injury of wrist and hand
0.797 0.203 0.000
S02.4 Fracture of malar and maxillary bones
0.797 0.203 0.000
J39 Other diseases of upper respiratory tract
0.797 0.203 0.000
S40-S49 Injuries to the shoulder and upper arm
0.797 0.203 0.000
Chapter V Mental and behavioural disorders
0.796 0.204 0.000
J34.8 Other specified disorders of nose and nasal sinuses
0.793 0.207 0.000
S01 Open wound of head
0.792 0.208 0.000
J00 Acute nasopharyngitis [common cold]
0.792 0.208 0.000
S05 Injury of eye and orbit
0.790 0.210 0.000
M23.3 Other meniscus derangements
0.790 0.210 0.000
J35 Chronic diseases of tonsils and adenoids
0.788 0.212 0.000
Z82.5 Family history of asthma and other chronic lower respiratory diseases
0.788 0.212 0.000
I63.2 Cerebral infarction due to unspecified occlusion or stenosis of precerebral arteries
0.787 0.213 0.000
M91-M94 Chondropathies
0.787 0.213 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.786 0.214 0.000
S10-S19 Injuries to the neck
0.784 0.216 0.000
I20.9 Angina pectoris, unspecified
0.781 0.219 0.000
M79.8 Other specified soft tissue disorders
0.781 0.219 0.000
M41 Scoliosis
0.781 0.219 0.000
S09.9 Unspecified injury of head
0.778 0.222 0.000
D68.2 Hereditary deficiency of other clotting factors
0.778 0.222 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.777 0.223 0.000
Y40 Systemic antibiotics
0.777 0.223 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.776 0.224 0.000
I62 Other nontraumatic intracranial haemorrhage
0.776 0.224 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.776 0.224 0.000
C77.9 Lymph node, unspecified
0.774 0.226 0.000
S68 Traumatic amputation of wrist and hand
0.771 0.229 0.000
S80.8 Other superficial injuries of lower leg
0.770 0.230 0.000
M86-M90 Other osteopathies
0.770 0.230 0.000
I67.1 Cerebral aneurysm, nonruptured
0.767 0.233 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.762 0.238 0.000
S80.9 Superficial injury of lower leg, unspecified
0.762 0.238 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.761 0.239 0.000
M23.8 Other internal derangements of knee
0.761 0.239 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.758 0.242 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.755 0.244 0.000
S02.8 Fractures of other skull and facial bones
0.755 0.245 0.000
D80-D89 Certain disorders involving the immune mechanism
0.754 0.246 0.000
Y95 Nosocomial condition
0.752 0.248 0.000
I77 Other disorders of arteries and arterioles
0.751 0.249 0.000
S89 Other and unspecified injuries of lower leg
0.750 0.250 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.750 0.250 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.750 0.250 0.000
C78.7 Secondary malignant neoplasm of liver
0.750 0.250 0.000
J95-J99 Other diseases of the respiratory system
0.750 0.250 0.000
I22 Subsequent myocardial infarction
0.749 0.251 0.000
M06 Other rheumatoid arthritis
0.748 0.252 0.000
S92 Fracture of foot, except ankle
0.747 0.253 0.000
M00-M03 Infectious arthropathies
0.747 0.253 0.000
J30 Vasomotor and allergic rhinitis
0.746 0.254 0.000
F30-F39 Mood [affective] disorders
0.746 0.254 0.000
S64 Injury of nerves at wrist and hand level
0.745 0.255 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.745 0.255 0.000
B34 Viral infection of unspecified site
0.744 0.256 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.744 0.256 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.744 0.256 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.742 0.258 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.741 0.259 0.000
I63.8 Other cerebral infarction
0.740 0.260 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.738 0.262 0.000
M50-M54 Other dorsopathies
0.737 0.263 0.000
Z81 Family history of mental and behavioural disorders
0.736 0.263 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.735 0.265 0.000
O80-O84 Delivery
0.733 0.267 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.730 0.270 0.000
M96 Postprocedural musculoskeletal disorders, not elsewhere classified
0.730 0.270 0.000
M23.32 Other meniscus derangements (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.730 0.270 0.000
T79-T79 Certain early complications of trauma
0.730 0.270 0.000
S02.40 Fracture of malar and maxillary bones (closed)
0.730 0.270 0.000
S51 Open wound of forearm
0.729 0.271 0.000
J02 Acute pharyngitis
0.729 0.271 0.000
S91 Open wound of ankle and foot
0.728 0.272 0.000
T66-T78 Other and unspecified effects of external causes
0.728 0.272 0.000
J14 Pneumonia due to Haemophilus influenzae
0.727 0.272 0.000
Z97 Presence of other devices
0.727 0.273 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.727 0.273 0.000
J34.3 Hypertrophy of nasal turbinates
0.725 0.275 0.000
T51 Toxic effect of alcohol
0.723 0.277 0.000
Z75 Problems related to medical facilities and other health care
0.723 0.277 0.000
T40.4 Other synthetic narcotics
0.723 0.277 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.722 0.278 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.722 0.278 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.721 0.279 0.000
Z93 Artificial opening status
0.720 0.280 0.000
X60-X84 Intentional self-harm
0.720 0.280 0.000
J15 Bacterial pneumonia, not elsewhere classified
0.720 0.280 0.000
S06.0 Concussion
0.719 0.281 0.000
M48.09 Spinal stenosis (Site unspecified)
0.719 0.281 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
Z84 Family history of other conditions
0.717 0.283 0.000
C77.5 Intrapelvic lymph nodes
0.717 0.283 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.716 0.283 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.716 0.283 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.716 0.283 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.716 0.283 0.000
Z92.9 Personal history of medical treatment, unspecified
0.716 0.284 0.000
Z92.5 Personal history of rehabilitation measures
0.716 0.284 0.000
I60.8 Other subarachnoid haemorrhage
0.715 0.285 0.000
S69 Other and unspecified injuries of wrist and hand
0.714 0.285 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.714 0.286 0.000
M23.26 Derangement of meniscus due to old tear or injury (Other and unspecified lateral meniscus)
0.714 0.286 0.000
V20-V29 Motorcycle rider injured in transport accident
0.714 0.286 0.000
B02 Zoster [herpes zoster]
0.714 0.286 0.000
J42 Unspecified chronic bronchitis
0.713 0.287 0.000
C80 Malignant neoplasm without specification of site
0.713 0.287 0.000
I63.6 Cerebral infarction due to cerebral venous thrombosis, nonpyogenic
0.711 0.289 0.000
I63.4 Cerebral infarction due to embolism of cerebral arteries
0.711 0.289 0.000
I63.3 Cerebral infarction due to thrombosis of cerebral arteries
0.711 0.289 0.000
I63.1 Cerebral infarction due to embolism of precerebral arteries
0.711 0.289 0.000
I63.0 Cerebral infarction due to thrombosis of precerebral arteries
0.711 0.289 0.000
I24.8 Other forms of acute ischaemic heart disease
0.711 0.289 0.000
M43 Other deforming dorsopathies
0.711 0.289 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.710 0.290 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.710 0.290 0.000
S67 Crushing injury of wrist and hand
0.709 0.291 0.000
Y86 Sequelae of other accidents
0.708 0.292 0.000
Z73 Problems related to life-management difficulty
0.706 0.294 0.000
W20-W49 Exposure to inanimate mechanical forces
0.705 0.295 0.000
Z95.2 Presence of prosthetic heart valve
0.704 0.296 0.000
J01 Acute sinusitis
0.703 0.297 0.000
M21 Other acquired deformities of limbs
0.703 0.297 0.000
S01.8 Open wound of other parts of head
0.702 0.298 0.000
M41.9 Scoliosis, unspecified
0.702 0.298 0.000
J32 Chronic sinusitis
0.702 0.298 0.000
Z82.8 Family history of other disabilities and chronic diseases leading to disablement, not elsewhere classified
0.702 0.298 0.000
Z82.7 Family history of congenital malformations, deformations and chromosomal abnormalities
0.702 0.298 0.000
Z82.6 Family history of arthritis and other diseases of the musculoskeletal system and connective tissue
0.702 0.298 0.000
Z82.2 Family history of deafness and hearing loss
0.702 0.298 0.000
Z82.1 Family history of blindness and visual loss
0.702 0.298 0.000
S65 Injury of blood vessels at wrist and hand level
0.702 0.298 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.702 0.298 0.000
M31 Other necrotising vasculopathies
0.702 0.298 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.702 0.298 0.000
Y52 Agents primarily affecting the cardiovascular system
0.701 0.299 0.000
S81 Open wound of lower leg
0.701 0.299 0.000
S08 Traumatic amputation of part of head
0.701 0.299 0.000
S07 Crushing injury of head
0.701 0.299 0.000
S04 Injury of cranial nerves
0.701 0.299 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.701 0.299 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.701 0.299 0.000
M71 Other bursopathies
0.700 0.299 0.000
Z89 Acquired absence of limb
0.700 0.300 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.700 0.300 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.699 0.301 0.000
M05 Seropositive rheumatoid arthritis
0.699 0.301 0.000
Z82.0 Family history of epilepsy and other diseases of the nervous system
0.698 0.302 0.000
S50 Superficial injury of forearm
0.698 0.302 0.000
B34.9 Viral infection, unspecified
0.697 0.303 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.696 0.304 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.696 0.304 0.000
J80 Adult respiratory distress syndrome
0.695 0.305 0.000
S02.0 Fracture of vault of skull
0.695 0.305 0.000
S61.1 Open wound of finger(s) with damage to nail
0.695 0.305 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.695 0.305 0.000
M95 Other acquired deformities of musculoskeletal system and connective tissue
0.694 0.306 0.000
I27 Other pulmonary heart diseases
0.693 0.307 0.000
J37 Chronic laryngitis and laryngotracheitis
0.693 0.307 0.000
I73 Other peripheral vascular diseases
0.693 0.307 0.000
Z86.6 Personal history of diseases of the nervous system and sense organs
0.693 0.307 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.692 0.308 0.000
Z92.8 Personal history of other medical treatment
0.691 0.309 0.000
I71 Aortic aneurysm and dissection
0.691 0.309 0.000
M75 Shoulder lesions
0.689 0.311 0.000
C60-C63 Malignant neoplasms of male genital organs
0.689 0.311 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.687 0.312 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.687 0.312 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.687 0.312 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.687 0.312 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.687 0.312 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.687 0.312 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.687 0.312 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.687 0.312 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.687 0.312 0.000
T36 Poisoning by systemic antibiotics
0.687 0.312 0.000
B35-B49 Mycoses
0.687 0.313 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.687 0.313 0.000
Y35-Y36 Legal intervention and operations of war
0.687 0.313 0.000
Y10-Y34 Event of undetermined intent
0.687 0.313 0.000
Y00-Y09 Assault
0.687 0.313 0.000
X85-X99 Assault
0.687 0.313 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.687 0.313 0.000
X50-X57 Overexertion, travel and privation
0.687 0.313 0.000
X30-X39 Exposure to forces of nature
0.687 0.313 0.000
X20-X29 Contact with venomous animals and plants
0.687 0.313 0.000
X10-X19 Contact with heat and hot substances
0.687 0.313 0.000
X00-X09 Exposure to smoke, fire and flames
0.687 0.313 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.687 0.313 0.000
W75-W84 Other accidental threats to breathing
0.687 0.313 0.000
W65-W74 Accidental drowning and submersion
0.687 0.313 0.000
W50-W64 Exposure to animate mechanical forces
0.687 0.313 0.000
V98-V99 Other and unspecified transport accidents
0.687 0.313 0.000
V95-V97 Air and space transport accidents
0.687 0.313 0.000
V90-V94 Water transport accidents
0.687 0.313 0.000
V80-V89 Other land transport accidents
0.687 0.313 0.000
V70-V79 Bus occupant injured in transport accident
0.687 0.313 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.687 0.313 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.687 0.313 0.000
V40-V49 Car occupant injured in transport accident
0.687 0.313 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.687 0.313 0.000
V01-V09 Pedestrian injured in transport accident
0.687 0.313 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.686 0.314 0.000
T84.3 Mechanical complication of other bone devices, implants and grafts
0.686 0.314 0.000
I61 Intracerebral haemorrhage
0.685 0.315 0.000
S06.5 Traumatic subdural haemorrhage
0.685 0.315 0.000
D66 Hereditary factor VIII deficiency
0.685 0.315 0.000
I28 Other diseases of pulmonary vessels
0.685 0.315 0.000
M06.9 Rheumatoid arthritis, unspecified
0.685 0.315 0.000
J46 Status asthmaticus
0.684 0.316 0.000
S40 Superficial injury of shoulder and upper arm
0.684 0.316 0.000
Z39 Postpartum care and examination
0.684 0.316 0.000
J41 Simple and mucopurulent chronic bronchitis
0.683 0.316 0.000
Z95.3 Presence of xenogenic heart valve
0.683 0.316 0.000
O00-O08 Pregnancy with abortive outcome
0.683 0.317 0.000
Y44 Agents primarily affecting blood constituents
0.683 0.317 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.683 0.317 0.000
S66.3 Injury of extensor muscle and tendon of other finger at wrist and hand level
0.682 0.317 0.000
S62.3 Fracture of other metacarpal bone
0.682 0.318 0.000
I67.2 Cerebral atherosclerosis
0.682 0.318 0.000
J45.8 Mixed asthma
0.680 0.320 0.000
J45.1 Nonallergic asthma
0.680 0.320 0.000
I67.8 Other specified cerebrovascular diseases
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.678 0.321 0.000
Y43.3 Other antineoplastic drugs
0.678 0.322 0.000
F31 Bipolar affective disorder
0.677 0.322 0.000
J35.0 Chronic tonsillitis
0.677 0.323 0.000
S62.7 Multiple fractures of fingers
0.676 0.324 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.676 0.324 0.000
Z36 Antenatal screening
0.676 0.324 0.000
J39.2 Other diseases of pharynx
0.676 0.324 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.675 0.325 0.000
T43.2 Other and unspecified antidepressants
0.674 0.326 0.000
J34.1 Cyst and mucocele of nose and nasal sinus
0.672 0.328 0.000
J34.0 Abscess, furuncle and carbuncle of nose
0.672 0.328 0.000
A30-A49 Other bacterial diseases
0.672 0.328 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.670 0.329 0.000
M79.5 Residual foreign body in soft tissue
0.670 0.330 0.000
S88 Traumatic amputation of lower leg
0.670 0.330 0.000
S87 Crushing injury of lower leg
0.670 0.330 0.000
S86 Injury of muscle and tendon at lower leg level
0.670 0.330 0.000
S85 Injury of blood vessels at lower leg level
0.670 0.330 0.000
S84 Injury of nerves at lower leg level
0.670 0.330 0.000
Z92.0 Personal history of contraception
0.670 0.330 0.000
I67.7 Cerebral arteritis, not elsewhere classified
0.668 0.332 0.000
I67.6 Nonpyogenic thrombosis of intracranial venous system
0.668 0.332 0.000
I67.5 Moyamoya disease
0.668 0.332 0.000
I67.4 Hypertensive encephalopathy
0.668 0.332 0.000
I67.3 Progressive vascular leukoencephalopathy
0.668 0.332 0.000
I67.0 Dissection of cerebral arteries, nonruptured
0.668 0.332 0.000
M23.81 Other internal derangements of knee (Anterior cruciate ligament or Anterior horn of medial meniscus)
0.668 0.332 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.668 0.332 0.000
I78 Diseases of capillaries
0.667 0.333 0.000
S60.8 Other superficial injuries of wrist and hand
0.667 0.333 0.000
I74 Arterial embolism and thrombosis
0.666 0.333 0.000
A00-A09 Intestinal infectious diseases
0.666 0.334 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.665 0.335 0.000
I05-I09 Chronic rheumatic heart diseases
0.664 0.335 0.000
S61.7 Multiple open wounds of wrist and hand
0.664 0.336 0.000
Y59 Other and unspecified vaccines and biological substances
0.664 0.336 0.000
Y58 Bacterial vaccines
0.664 0.336 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.664 0.336 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.664 0.336 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.664 0.336 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.664 0.336 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.664 0.336 0.000
Y48 Anaesthetics and therapeutic gases
0.664 0.336 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.664 0.336 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.664 0.336 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.664 0.336 0.000
S02.3 Fracture of orbital floor
0.664 0.336 0.000
M48.02 Spinal stenosis (Cervical region)
0.664 0.336 0.000
M48.00 Spinal stenosis (Multiple sites in spine)
0.664 0.336 0.000
Chapter XXII Codes for special purposes
0.662 0.338 0.000
M76 Enthesopathies of lower limb, excluding foot
0.662 0.338 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.662 0.338 0.000
J44 Other chronic obstructive pulmonary disease
0.661 0.339 0.000
T39.1 4-Aminophenol derivatives
0.661 0.339 0.000
M15-M19 Arthrosis
0.661 0.339 0.000
C77.2 Intra-abdominal lymph nodes
0.661 0.339 0.000
I26.0 Pulmonary embolism with mention of acute cor pulmonale
0.661 0.339 0.000
M49 Spondylopathies in diseases classified elsewhere
0.658 0.342 0.000
S02.80 Fractures of other skull and facial bones (closed)
0.658 0.342 0.000
J33 Nasal polyp
0.658 0.342 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.655 0.345 0.000
J04 Acute laryngitis and tracheitis
0.653 0.347 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.653 0.347 0.000
M23.33 Other meniscus derangements (Medial collateral ligament or Other and unspecified medial meniscus)
0.652 0.348 0.000
M79.86 Other specified soft tissue disorders (Lower leg)
0.652 0.348 0.000
T86 Failure and rejection of transplanted organs and tissues
0.652 0.348 0.000
C78.0 Secondary malignant neoplasm of lung
0.651 0.349 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.651 0.349 0.000
Z95.4 Presence of other heart-valve replacement
0.651 0.349 0.000
Y43.0 Antiallergic and antiemetic drugs
0.650 0.349 0.000
M47 Spondylosis
0.650 0.350 0.000
M79.0 Rheumatism, unspecified
0.650 0.350 0.000
S66.0 Injury of long flexor muscle and tendon of thumb at wrist and hand level
0.649 0.351 0.000
F99-F99 Unspecified mental disorder
0.649 0.351 0.000
Z82.3 Family history of stroke
0.648 0.352 0.000
B99-B99 Other infectious diseases
0.648 0.352 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.648 0.352 0.000
B65-B83 Helminthiases
0.648 0.352 0.000
B50-B64 Protozoal diseases
0.648 0.352 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.648 0.352 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.648 0.352 0.000
A80-A89 Viral infections of the central nervous system
0.648 0.352 0.000
A75-A79 Rickettsioses
0.648 0.352 0.000
A70-A74 Other diseases caused by chlamydiae
0.648 0.352 0.000
A65-A69 Other spirochaetal diseases
0.648 0.352 0.000
A20-A28 Certain zoonotic bacterial diseases
0.648 0.352 0.000
A15-A19 Tuberculosis
0.648 0.352 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.647 0.353 0.000
M79.6 Pain in limb
0.646 0.354 0.000
I20.8 Other forms of angina pectoris
0.646 0.354 0.000
I72 Other aneurysm
0.646 0.354 0.000
T40.2 Other opioids
0.645 0.354 0.000
O80 Single spontaneous delivery
0.646 0.354 0.000
V10-V19 Pedal cyclist injured in transport accident
0.645 0.355 0.000
F33 Recurrent depressive disorder
0.643 0.357 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.643 0.357 0.000
M23.83 Other internal derangements of knee (Medial collateral ligament or Other and unspecified medial meniscus)
0.642 0.358 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.642 0.358 0.000
Y51.7 Beta-Adrenoreceptor antagonists, not elsewhere classified
0.642 0.358 0.000
M10 Gout
0.641 0.359 0.000
Z75.1 Person awaiting admission to adequate facility elsewhere
0.640 0.360 0.000
S02.9 Fracture of skull and facial bones, part unspecified
0.639 0.361 0.000
S02.7 Multiple fractures involving skull and facial bones
0.639 0.361 0.000
S02.5 Fracture of tooth
0.639 0.361 0.000
S62.6 Fracture of other finger
0.639 0.361 0.000
B15-B19 Viral hepatitis
0.638 0.362 0.000
M42 Spinal osteochondrosis
0.638 0.362 0.000
M40 Kyphosis and lordosis
0.638 0.362 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.638 0.362 0.000
I25.5 Ischaemic cardiomyopathy
0.638 0.362 0.000
M79.1 Myalgia
0.637 0.363 0.000
T51.0 Ethanol
0.637 0.363 0.000
I70 Atherosclerosis
0.637 0.363 0.000
M77 Other enthesopathies
0.637 0.363 0.000
M79.89 Other specified soft tissue disorders (Site unspecified)
0.636 0.364 0.000
T92 Sequelae of injuries of upper limb
0.636 0.364 0.000
C64-C68 Malignant neoplasms of urinary tract
0.636 0.364 0.000
I77.6 Arteritis, unspecified
0.635 0.365 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.635 0.365 0.000
Z76 Persons encountering health services in other circumstances
0.634 0.365 0.000
D55-D59 Haemolytic anaemias
0.634 0.365 0.000
Z95.1 Presence of aortocoronary bypass graft
0.634 0.366 0.000
M48.9 Spondylopathy, unspecified
0.634 0.366 0.000
M48.8 Other specified spondylopathies
0.634 0.366 0.000
M48.5 Collapsed vertebra, not elsewhere classified
0.634 0.366 0.000
M48.4 Fatigue fracture of vertebra
0.634 0.366 0.000
M48.3 Traumatic spondylopathy
0.634 0.366 0.000
M48.2 Kissing spine
0.634 0.366 0.000
M48.1 Ankylosing hyperostosis [Forestier]
0.634 0.366 0.000
M96.0 Pseudarthrosis after fusion or arthrodesis
0.633 0.367 0.000
S99 Other and unspecified injuries of ankle and foot
0.633 0.367 0.000
S98 Traumatic amputation of ankle and foot
0.633 0.367 0.000
S97 Crushing injury of ankle and foot
0.633 0.367 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.633 0.367 0.000
S95 Injury of blood vessels at ankle and foot level
0.633 0.367 0.000
S94 Injury of nerves at ankle and foot level
0.633 0.367 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.633 0.367 0.000
S90 Superficial injury of ankle and foot
0.633 0.367 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.632 0.368 0.000
S70-S79 Injuries to the hip and thigh
0.631 0.369 0.000
Y57 Other and unspecified drugs and medicaments
0.631 0.369 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.631 0.369 0.000
S92.3 Fracture of metatarsal bone
0.631 0.369 0.000
S01.4 Open wound of cheek and temporomandibular area
0.629 0.370 0.000
S19 Other and unspecified injuries of neck
0.629 0.371 0.000
I24.1 Dressler's syndrome
0.629 0.371 0.000
Y40.3 Macrolides
0.629 0.371 0.000
T39.0 Salicylates
0.629 0.371 0.000
M80-M85 Disorders of bone density and structure
0.628 0.372 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.628 0.372 0.000
S62.2 Fracture of first metacarpal bone
0.628 0.372 0.000
I60.7 Subarachnoid haemorrhage from intracranial artery, unspecified
0.627 0.373 0.000
I60.6 Subarachnoid haemorrhage from other intracranial arteries
0.627 0.373 0.000
I60.5 Subarachnoid haemorrhage from vertebral artery
0.627 0.373 0.000
I60.4 Subarachnoid haemorrhage from basilar artery
0.627 0.373 0.000
I60.3 Subarachnoid haemorrhage from posterior communicating artery
0.627 0.373 0.000
I60.1 Subarachnoid haemorrhage from middle cerebral artery
0.627 0.373 0.000
I60.0 Subarachnoid haemorrhage from carotid siphon and bifurcation
0.627 0.373 0.000
S62.5 Fracture of thumb
0.626 0.374 0.000
F31.9 Bipolar affective disorder, unspecified
0.626 0.374 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.625 0.375 0.000
S80.7 Multiple superficial injuries of lower leg
0.625 0.375 0.000
S80.1 Contusion of other and unspecified parts of lower leg
0.625 0.375 0.000
S80.0 Contusion of knee
0.625 0.375 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.624 0.375 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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