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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs146081892
log Bayes Factor = 11.9524
Chromosome 4   position 41,981,814  (GRCh37) Explore rs146081892 on Ensembl!
Variant rs146081892 is part of Cluster X0020

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter II Neoplasms
1.000 0.000 0.000
N30-N39 Other diseases of urinary system
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
I21 Acute myocardial infarction
0.997 0.003 0.000
N17-N19 Renal failure
0.997 0.003 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.997 0.003 0.000
N18 Chronic renal failure
0.995 0.005 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.994 0.006 0.000
I21.9 Acute myocardial infarction, unspecified
0.994 0.006 0.000
N39 Other disorders of urinary system
0.989 0.011 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.988 0.012 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.986 0.014 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.986 0.014 0.000
N18.9 Chronic renal failure, unspecified
0.985 0.015 0.000
Chapter I Certain infectious and parasitic diseases
0.981 0.019 0.000
I30-I52 Other forms of heart disease
0.980 0.020 0.000
M05-M14 Inflammatory polyarthropathies
0.979 0.021 0.000
M06 Other rheumatoid arthritis
0.975 0.025 0.000
M06.9 Rheumatoid arthritis, unspecified
0.972 0.028 0.000
I25 Chronic ischaemic heart disease
0.970 0.030 0.000
C79 Secondary malignant neoplasm of other sites
0.965 0.035 0.000
N39.4 Other specified urinary incontinence
0.964 0.036 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.963 0.037 0.000
Chapter XX External causes of morbidity and mortality
0.962 0.038 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.961 0.039 0.000
I50 Heart failure
0.960 0.040 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.959 0.041 0.000
E00-E07 Disorders of thyroid gland
0.956 0.044 0.000
C15-C26 Malignant neoplasms of digestive organs
0.956 0.044 0.000
N32 Other disorders of bladder
0.955 0.045 0.000
I42 Cardiomyopathy
0.955 0.045 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.954 0.046 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.941 0.059 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.940 0.060 0.000
E70-E90 Metabolic disorders
0.939 0.061 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.938 0.062 0.000
I25.1 Atherosclerotic heart disease
0.933 0.067 0.000
N32.8 Other specified disorders of bladder
0.931 0.069 0.000
B25-B34 Other viral diseases
0.926 0.074 0.000
N18.5 Chronic kidney disease, stage 5
0.923 0.077 0.000
E03 Other hypothyroidism
0.919 0.081 0.000
C78.7 Secondary malignant neoplasm of liver
0.917 0.083 0.000
B95-B98 Bacterial, viral and other infectious agents
0.914 0.086 0.000
I50.9 Heart failure, unspecified
0.913 0.087 0.000
M80-M85 Disorders of bone density and structure
0.913 0.087 0.000
N30 Cystitis
0.912 0.088 0.000
D00-D09 In situ neoplasms
0.911 0.089 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.909 0.091 0.000
I42.9 Cardiomyopathy, unspecified
0.904 0.096 0.000
I24 Other acute ischaemic heart diseases
0.903 0.097 0.000
N39.8 Other specified disorders of urinary system
0.894 0.106 0.000
I22 Subsequent myocardial infarction
0.894 0.106 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.892 0.108 0.000
E03.9 Hypothyroidism, unspecified
0.892 0.108 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.890 0.110 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.883 0.117 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.882 0.118 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.882 0.118 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.871 0.129 0.000
B34 Viral infection of unspecified site
0.869 0.131 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.864 0.136 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.861 0.139 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.861 0.139 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.857 0.143 0.000
E83 Disorders of mineral metabolism
0.854 0.146 0.000
I25.2 Old myocardial infarction
0.850 0.150 0.000
I24.8 Other forms of acute ischaemic heart disease
0.841 0.159 0.000
M40-M43 Deforming dorsopathies
0.841 0.159 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.836 0.164 0.000
Y43 Primarily systemic agents
0.834 0.166 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.833 0.167 0.000
N18.0 End-stage renal disease
0.831 0.169 0.000
N72 Inflammatory disease of cervix uteri
0.829 0.171 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.829 0.171 0.000
M10 Gout
0.827 0.173 0.000
E20-E35 Disorders of other endocrine glands
0.827 0.173 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.826 0.174 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.823 0.177 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.822 0.178 0.000
I50.0 Congestive heart failure
0.820 0.180 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.818 0.182 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.818 0.182 0.000
N39.9 Disorder of urinary system, unspecified
0.815 0.185 0.000
B34.9 Viral infection, unspecified
0.812 0.188 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.811 0.189 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.809 0.191 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.808 0.192 0.000
M84 Disorders of continuity of bone
0.807 0.193 0.000
A30-A49 Other bacterial diseases
0.807 0.193 0.000
T86 Failure and rejection of transplanted organs and tissues
0.807 0.193 0.000
C18 Malignant neoplasm of colon
0.806 0.194 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.806 0.194 0.000
I38 Endocarditis, valve unspecified
0.805 0.195 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.805 0.195 0.000
Chapter XXII Codes for special purposes
0.805 0.195 0.000
V10-V19 Pedal cyclist injured in transport accident
0.804 0.195 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.804 0.196 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.804 0.196 0.000
L60-L75 Disorders of skin appendages
0.804 0.196 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.803 0.197 0.000
M65-M68 Disorders of synovium and tendon
0.802 0.198 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.801 0.198 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.800 0.200 0.000
N17 Acute renal failure
0.799 0.201 0.000
N39.3 Stress incontinence
0.799 0.201 0.000
E05.9 Thyrotoxicosis, unspecified
0.797 0.203 0.000
S70-S79 Injuries to the hip and thigh
0.796 0.204 0.000
I50.1 Left ventricular failure
0.795 0.205 0.000
T79-T79 Certain early complications of trauma
0.794 0.205 0.000
N30.1 Interstitial cystitis (chronic)
0.793 0.207 0.000
M00-M03 Infectious arthropathies
0.791 0.209 0.000
W00-W19 Falls
0.791 0.209 0.000
C78.0 Secondary malignant neoplasm of lung
0.788 0.212 0.000
V40-V49 Car occupant injured in transport accident
0.786 0.214 0.000
N18.4 Chronic kidney disease, stage 4
0.786 0.214 0.000
M86-M90 Other osteopathies
0.786 0.214 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.784 0.216 0.000
L03 Cellulitis
0.784 0.216 0.000
T85.6 Mechanical complication of other specified internal prosthetic devices, implants and grafts
0.783 0.217 0.000
Y43.3 Other antineoplastic drugs
0.783 0.217 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.782 0.218 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.781 0.219 0.000
I25.3 Aneurysm of heart
0.780 0.220 0.000
I42.1 Obstructive hypertrophic cardiomyopathy
0.779 0.221 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.779 0.221 0.000
C15 Malignant neoplasm of oesophagus
0.777 0.223 0.000
T85.9 Unspecified complication of internal prosthetic device, implant and graft
0.776 0.224 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.776 0.224 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.775 0.225 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.774 0.226 0.000
T82.3 Mechanical complication of other vascular grafts
0.773 0.227 0.000
N10-N16 Renal tubulo-interstitial diseases
0.773 0.227 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.773 0.227 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.771 0.229 0.000
C17 Malignant neoplasm of small intestine
0.771 0.229 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.771 0.229 0.000
I42.6 Alcoholic cardiomyopathy
0.769 0.231 0.000
N30.8 Other cystitis
0.768 0.232 0.000
N30.2 Other chronic cystitis
0.767 0.233 0.000
S40-S49 Injuries to the shoulder and upper arm
0.767 0.233 0.000
S90-S99 Injuries to the ankle and foot
0.765 0.235 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.764 0.236 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.764 0.236 0.000
D46 Myelodysplastic syndromes
0.763 0.237 0.000
S20-S29 Injuries to the thorax
0.762 0.238 0.000
N75 Diseases of Bartholin's gland
0.761 0.239 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.760 0.240 0.000
T82.1 Mechanical complication of cardiac electronic device
0.759 0.241 0.000
N35 Urethral stricture
0.759 0.241 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.758 0.242 0.000
I42.0 Dilated cardiomyopathy
0.758 0.242 0.000
T85.4 Mechanical complication of breast prosthesis and implant
0.757 0.243 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.756 0.244 0.000
X50-X57 Overexertion, travel and privation
0.756 0.244 0.000
T91 Sequelae of injuries of neck and trunk
0.755 0.245 0.000
M91-M94 Chondropathies
0.755 0.245 0.000
L60 Nail disorders
0.752 0.247 0.000
I10-I15 Hypertensive diseases
0.752 0.248 0.000
I34 Nonrheumatic mitral valve disorders
0.752 0.248 0.000
N32.1 Vesicointestinal fistula
0.751 0.249 0.000
E83.5 Disorders of calcium metabolism
0.750 0.250 0.000
N25-N29 Other disorders of kidney and ureter
0.750 0.250 0.000
L03.9 Cellulitis, unspecified
0.750 0.250 0.000
C79.2 Secondary malignant neoplasm of skin
0.749 0.251 0.000
N70 Salpingitis and oophoritis
0.749 0.251 0.000
M85 Other disorders of bone density and structure
0.748 0.251 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.747 0.253 0.000
N30.0 Acute cystitis
0.745 0.255 0.000
D07 Carcinoma in situ of other and unspecified genital organs
0.745 0.255 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.744 0.256 0.000
L02.4 Cutaneous abscess, furuncle and carbuncle of limb
0.743 0.257 0.000
B25 Cytomegaloviral disease
0.743 0.257 0.000
I60-I69 Cerebrovascular diseases
0.742 0.258 0.000
N99-N99 Other disorders of the genitourinary system
0.742 0.258 0.000
E86 Volume depletion
0.741 0.259 0.000
M43 Other deforming dorsopathies
0.741 0.259 0.000
N71 Inflammatory disease of uterus, except cervix
0.739 0.261 0.000
N32.0 Bladder-neck obstruction
0.739 0.261 0.000
D48.1 Connective and other soft tissue
0.739 0.261 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.739 0.261 0.000
I30 Acute pericarditis
0.738 0.262 0.000
C91 Lymphoid leukaemia
0.738 0.262 0.000
T85.3 Mechanical complication of other ocular prosthetic devices, imnplants and grafts
0.737 0.263 0.000
C16 Malignant neoplasm of stomach
0.737 0.263 0.000
S60-S69 Injuries to the wrist and hand
0.731 0.269 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.730 0.270 0.000
I27 Other pulmonary heart diseases
0.729 0.271 0.000
E78.5 Hyperlipidaemia, unspecified
0.729 0.271 0.000
D04 Carcinoma in situ of skin
0.728 0.272 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.728 0.272 0.000
S50-S59 Injuries to the elbow and forearm
0.727 0.273 0.000
D03 Melanoma in situ
0.726 0.274 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.726 0.274 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.726 0.274 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.725 0.275 0.000
N76 Other inflammation of vagina and vulva
0.724 0.276 0.000
C85.1 B-cell lymphoma, unspecified
0.724 0.276 0.000
M07 Psoriatic and enteropathic arthropathies
0.721 0.278 0.000
I05-I09 Chronic rheumatic heart diseases
0.721 0.279 0.000
T98 Sequelae of other and unspecified effects of external causes
0.718 0.281 0.000
M10.9 Gout, unspecified
0.718 0.282 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
N37 Urethral disorders in diseases classified elsewhere
0.717 0.283 0.000
N34 Urethritis and urethral syndrome
0.717 0.283 0.000
N33 Bladder disorders in diseases classified elsewhere
0.717 0.283 0.000
M81 Osteoporosis without pathological fracture
0.716 0.284 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.716 0.284 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.715 0.285 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.715 0.285 0.000
T87 Complications peculiar to reattachment and amputation
0.715 0.285 0.000
N18.8 Other chronic renal failure
0.714 0.286 0.000
N18.1 Chronic kidney disease, stage 1
0.714 0.286 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.713 0.287 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.713 0.287 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.713 0.287 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.713 0.287 0.000
N18.2 Chronic kidney disease, stage 2
0.712 0.288 0.000
E87.5 Hyperkalaemia
0.710 0.290 0.000
N39.2 Orthostatic proteinuria, unspecified
0.709 0.291 0.000
N39.1 Persistent proteinuria, unspecified
0.709 0.291 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.708 0.292 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.708 0.292 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.708 0.292 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.708 0.292 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.708 0.292 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.707 0.293 0.000
M60-M63 Disorders of muscles
0.707 0.293 0.000
C81 Hodgkin's disease
0.706 0.294 0.000
M11 Other crystal arthropathies
0.706 0.294 0.000
N00-N08 Glomerular diseases
0.705 0.295 0.000
A80-A89 Viral infections of the central nervous system
0.704 0.296 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.703 0.296 0.000
I51 Complications and ill-defined descriptions of heart disease
0.703 0.297 0.000
B99-B99 Other infectious diseases
0.703 0.297 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.703 0.297 0.000
B65-B83 Helminthiases
0.703 0.297 0.000
B50-B64 Protozoal diseases
0.703 0.297 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.703 0.297 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.703 0.297 0.000
A75-A79 Rickettsioses
0.703 0.297 0.000
A70-A74 Other diseases caused by chlamydiae
0.703 0.297 0.000
A65-A69 Other spirochaetal diseases
0.703 0.297 0.000
A20-A28 Certain zoonotic bacterial diseases
0.703 0.297 0.000
A15-A19 Tuberculosis
0.703 0.297 0.000
L60.0 Ingrowing nail
0.703 0.297 0.000
I52 Other heart disorders in diseases classified elsewhere
0.702 0.297 0.000
I48 Atrial fibrillation and flutter
0.702 0.297 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.702 0.297 0.000
I41 Myocarditis in diseases classified elsewhere
0.702 0.297 0.000
I40 Acute myocarditis
0.702 0.297 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.702 0.297 0.000
I37 Pulmonary valve disorders
0.702 0.297 0.000
I36 Nonrheumatic tricuspid valve disorders
0.702 0.297 0.000
I32 Pericarditis in diseases classified elsewhere
0.702 0.297 0.000
M14 Arthropathies in other diseases classified elsewhere
0.702 0.298 0.000
M12 Other specific arthropathies
0.702 0.298 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.702 0.298 0.000
M08 Juvenile arthritis
0.702 0.298 0.000
D06 Carcinoma in situ of cervix uteri
0.702 0.298 0.000
M06.8 Other specified rheumatoid arthritis
0.699 0.301 0.000
M06.4 Inflammatory polyarthropathy
0.699 0.301 0.000
M06.3 Rheumatoid nodule
0.699 0.301 0.000
M06.2 Rheumatoid bursitis
0.699 0.301 0.000
M06.1 Adult-onset Still's disease
0.699 0.301 0.000
M84.1 Nonunion of fracture [pseudarthrosis]
0.699 0.301 0.000
T83.0 Mechanical complication of urinary (indwelling) catheter
0.699 0.301 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.698 0.302 0.000
E23 Hypofunction and other disorders of pituitary gland
0.698 0.302 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.697 0.303 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.697 0.303 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.697 0.303 0.000
L08 Other local infections of skin and subcutaneous tissue
0.696 0.304 0.000
T93 Sequelae of injuries of lower limb
0.696 0.304 0.000
I25.6 Silent myocardial ischaemia
0.695 0.305 0.000
I25.4 Coronary artery aneurysm
0.695 0.305 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.695 0.305 0.000
W02 Fall involving ice-skates, skis, roller-skates or skateboards
0.695 0.305 0.000
B34.8 Other viral infections of unspecified site
0.694 0.306 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.694 0.306 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.693 0.306 0.000
C80 Malignant neoplasm without specification of site
0.693 0.307 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.692 0.308 0.000
C79.6 Secondary malignant neoplasm of ovary
0.692 0.308 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.692 0.308 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.692 0.308 0.000
V18 Pedal cyclist injured in noncollision transport accident
0.692 0.308 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.690 0.310 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.690 0.310 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.690 0.310 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.690 0.310 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.690 0.310 0.000
Y35-Y36 Legal intervention and operations of war
0.690 0.310 0.000
Y10-Y34 Event of undetermined intent
0.690 0.310 0.000
Y00-Y09 Assault
0.690 0.310 0.000
X85-X99 Assault
0.690 0.310 0.000
X60-X84 Intentional self-harm
0.690 0.310 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.690 0.310 0.000
X30-X39 Exposure to forces of nature
0.690 0.310 0.000
X20-X29 Contact with venomous animals and plants
0.690 0.310 0.000
X10-X19 Contact with heat and hot substances
0.690 0.310 0.000
X00-X09 Exposure to smoke, fire and flames
0.690 0.310 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.690 0.310 0.000
W75-W84 Other accidental threats to breathing
0.690 0.310 0.000
W65-W74 Accidental drowning and submersion
0.690 0.310 0.000
W50-W64 Exposure to animate mechanical forces
0.690 0.310 0.000
V98-V99 Other and unspecified transport accidents
0.690 0.310 0.000
V95-V97 Air and space transport accidents
0.690 0.310 0.000
V90-V94 Water transport accidents
0.690 0.310 0.000
V80-V89 Other land transport accidents
0.690 0.310 0.000
V70-V79 Bus occupant injured in transport accident
0.690 0.310 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.690 0.310 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.690 0.310 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.690 0.310 0.000
V01-V09 Pedestrian injured in transport accident
0.690 0.310 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.689 0.311 0.000
D45 Polycythaemia vera
0.689 0.311 0.000
T85.2 Mechanical complication of intraocular lens
0.688 0.312 0.000
T85.1 Mechanical complication of implanted electronic stimulator of nervous system
0.688 0.312 0.000
T85.0 Mechanical complication of ventricular intracranial (communicating) shunt
0.688 0.312 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.687 0.313 0.000
E40-E46 Malnutrition
0.687 0.313 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.687 0.313 0.000
N31.9 Neuromuscular dysfunction of bladder, unspecified
0.687 0.313 0.000
Y52 Agents primarily affecting the cardiovascular system
0.686 0.314 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.686 0.314 0.000
E00 Congenital iodine-deficiency syndrome
0.686 0.314 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.686 0.314 0.000
C25 Malignant neoplasm of pancreas
0.686 0.314 0.000
V20-V29 Motorcycle rider injured in transport accident
0.685 0.315 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.685 0.315 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.685 0.315 0.000
C21 Malignant neoplasm of anus and anal canal
0.685 0.315 0.000
C23 Malignant neoplasm of gallbladder
0.685 0.315 0.000
N32.4 Rupture of bladder, nontraumatic
0.685 0.315 0.000
N32.2 Vesical fistula, not elsewhere classified
0.685 0.315 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.685 0.315 0.000
I42.8 Other cardiomyopathies
0.685 0.315 0.000
I42.7 Cardiomyopathy due to drugs and other external agents
0.685 0.315 0.000
I42.5 Other restrictive cardiomyopathy
0.685 0.315 0.000
I42.4 Endocardial fibroelastosis
0.685 0.315 0.000
I42.3 Endomyocardial (eosinophilic) disease
0.685 0.315 0.000
M06.0 Seronegative rheumatoid arthritis
0.684 0.315 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.684 0.316 0.000
C15.9 Oesophagus, unspecified
0.684 0.316 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.683 0.317 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.682 0.317 0.000
C18.7 Sigmoid colon
0.682 0.318 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.681 0.319 0.000
D37.4 Colon
0.679 0.320 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.679 0.321 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.679 0.321 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.678 0.321 0.000
T84.6 Infection and inflammatory reaction due to internal fixation device [any site]
0.677 0.323 0.000
E83.1 Disorders of iron metabolism
0.677 0.323 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.677 0.323 0.000
E50-E64 Other nutritional deficiencies
0.675 0.324 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.674 0.325 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.674 0.325 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.674 0.325 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.674 0.325 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.674 0.325 0.000
C07 Malignant neoplasm of parotid gland
0.674 0.326 0.000
C96 Other and unspecified malignant neoplasms of lymphoid, haematopoietic and related tissue
0.674 0.326 0.000
C95 Leukaemia of unspecified cell type
0.674 0.326 0.000
C94 Other leukaemias of specified cell type
0.674 0.326 0.000
C93 Monocytic leukaemia
0.674 0.326 0.000
C88 Malignant immunoproliferative diseases
0.674 0.326 0.000
C86 Other specified types of T/NK-cell lymphoma
0.674 0.326 0.000
C84 Peripheral and cutaneous T-cell lymphomas
0.674 0.326 0.000
E85 Amyloidosis
0.673 0.327 0.000
E84 Cystic fibrosis
0.673 0.327 0.000
E79 Disorders of purine and pyrimidine metabolism
0.673 0.327 0.000
E77 Disorders of glycoprotein metabolism
0.673 0.327 0.000
E76 Disorders of glycosaminoglycan metabolism
0.673 0.327 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.673 0.327 0.000
E74 Other disorders of carbohydrate metabolism
0.673 0.327 0.000
E73 Lactose intolerance
0.673 0.327 0.000
E72 Other disorders of amino-acid metabolism
0.673 0.327 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.673 0.327 0.000
E70 Disorders of aromatic amino-acid metabolism
0.673 0.327 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.673 0.327 0.000
B35-B49 Mycoses
0.673 0.327 0.000
N74 Female pelvic inflammatory disorders in diseases classified elsewhere
0.673 0.327 0.000
Y40 Systemic antibiotics
0.673 0.327 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.672 0.328 0.000
Y43.0 Antiallergic and antiemetic drugs
0.671 0.328 0.000
A41 Other septicaemia
0.670 0.330 0.000
M43.1 Spondylolisthesis
0.670 0.330 0.000
L65 Other nonscarring hair loss
0.669 0.331 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.668 0.332 0.000
T80.2 Infections following infusion, transfusion and therapeutic injection
0.667 0.333 0.000
I46 Cardiac arrest
0.664 0.335 0.000
I42.2 Other hypertrophic cardiomyopathy
0.664 0.336 0.000
B33 Other viral diseases, not elsewhere classified
0.664 0.336 0.000
B30 Viral conjunctivitis
0.664 0.336 0.000
B27 Infectious mononucleosis
0.664 0.336 0.000
B26 Mumps
0.664 0.336 0.000
D05 Carcinoma in situ of breast
0.664 0.336 0.000
C92 Myeloid leukaemia
0.663 0.337 0.000
E04 Other non-toxic goitre
0.663 0.337 0.000
L70 Acne
0.662 0.337 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.661 0.338 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.661 0.339 0.000
S72 Fracture of femur
0.661 0.339 0.000
V48 Car occupant injured in noncollision transport accident
0.660 0.340 0.000
T66-T78 Other and unspecified effects of external causes
0.660 0.340 0.000
D09 Carcinoma in situ of other and unspecified sites
0.659 0.340 0.000
C51-C58 Malignant neoplasms of female genital organs
0.659 0.341 0.000
E03.8 Other specified hypothyroidism
0.659 0.341 0.000
E03.5 Myxoedema coma
0.659 0.341 0.000
E03.4 Atrophy of thyroid (acquired)
0.659 0.341 0.000
E03.3 Postinfectious hypothyroidism
0.659 0.341 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.659 0.341 0.000
E03.1 Congenital hypothyroidism without goitre
0.659 0.341 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.659 0.341 0.000
D37.5 Rectum
0.659 0.341 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.658 0.342 0.000
M67 Other disorders of synovium and tendon
0.658 0.342 0.000
N17.9 Acute renal failure, unspecified
0.657 0.343 0.000
T90 Sequelae of injuries of head
0.656 0.344 0.000
M05 Seropositive rheumatoid arthritis
0.655 0.344 0.000
M83 Adult osteomalacia
0.655 0.345 0.000
M82 Osteoporosis in diseases classified elsewhere
0.655 0.345 0.000
N30.4 Irradiation cystitis
0.654 0.346 0.000
I45 Other conduction disorders
0.654 0.346 0.000
D02 Carcinoma in situ of middle ear and respiratory system
0.653 0.347 0.000
D01 Carcinoma in situ of other and unspecified digestive organs
0.653 0.347 0.000
D00 Carcinoma in situ of oral cavity, oesophagus and stomach
0.653 0.347 0.000
D37.6 Liver, gallbladder and bile ducts
0.652 0.348 0.000
M80 Osteoporosis with pathological fracture
0.652 0.348 0.000
M00 Pyogenic arthritis
0.652 0.348 0.000
E88 Other metabolic disorders
0.651 0.349 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.651 0.349 0.000
B15-B19 Viral hepatitis
0.649 0.351 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.649 0.351 0.000
I24.1 Dressler's syndrome
0.647 0.352 0.000
Q80-Q89 Other congenital malformations
0.644 0.356 0.000
N19 Unspecified renal failure
0.644 0.356 0.000
M86 Osteomyelitis
0.644 0.356 0.000
N26 Unspecified contracted kidney
0.643 0.357 0.000
N77 Vulvovaginal ulceration and inflammation in diseases classified elsewhere
0.643 0.357 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.643 0.357 0.000
C18.3 Hepatic flexure
0.642 0.358 0.000
M84.4 Pathological fracture, not elsewhere classified
0.641 0.358 0.000
C83.8 Other types of diffuse non-Hodgkin's lymphoma
0.641 0.359 0.000
Chapter V Mental and behavioural disorders
0.641 0.359 0.000
I22.8 Subsequent myocardial infarction of other sites
0.641 0.359 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.641 0.359 0.000
I25.5 Ischaemic cardiomyopathy
0.640 0.360 0.000
L10-L14 Bullous disorders
0.640 0.360 0.000
E83.4 Disorders of magnesium metabolism
0.639 0.361 0.000
T95 Sequelae of burns, corrosions and frostbite
0.638 0.362 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.638 0.362 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.638 0.362 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.638 0.362 0.000
C17.9 Small intestine, unspecified
0.638 0.362 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.637 0.362 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.636 0.364 0.000
D46.9 Myelodysplastic syndrome, unspecified
0.636 0.364 0.000
N18.3 Chronic kidney disease, stage 3
0.636 0.364 0.000
C64-C68 Malignant neoplasms of urinary tract
0.635 0.365 0.000
T91.1 Sequelae of fracture of spine
0.635 0.365 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.635 0.365 0.000
Y59 Other and unspecified vaccines and biological substances
0.633 0.367 0.000
Y58 Bacterial vaccines
0.633 0.367 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.633 0.367 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.633 0.367 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.633 0.367 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.633 0.367 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.633 0.367 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.633 0.367 0.000
Y48 Anaesthetics and therapeutic gases
0.633 0.367 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.633 0.367 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.633 0.367 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.633 0.367 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.633 0.367 0.000
N31.2 Flaccid neuropathic bladder, not elsewhere classified
0.632 0.367 0.000
N31.1 Reflex neuropathic bladder, not elsewhere classified
0.632 0.367 0.000
N31.0 Uninhibited neuropathic bladder, not elsewhere classified
0.632 0.367 0.000
E83.3 Disorders of phosphorus metabolism
0.632 0.368 0.000
N75.0 Cyst of Bartholin's gland
0.632 0.368 0.000
M45-M49 Spondylopathies
0.632 0.368 0.000
T86.1 Kidney transplant failure and rejection
0.632 0.368 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.632 0.368 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.632 0.368 0.000
E78.4 Other hyperlipidaemia
0.632 0.368 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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