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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs147338646
log Bayes Factor = 5.39391
Chromosome 9   position 11,812,813  (GRCh37) Explore rs147338646 on Ensembl!
Variant rs147338646 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
0.999 0.001 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.991 0.009 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.990 0.010 0.000
I84 Haemorrhoids
0.979 0.021 0.000
Chapter II Neoplasms
0.979 0.021 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.979 0.021 0.000
I30-I52 Other forms of heart disease
0.963 0.037 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.958 0.042 0.000
D10-D36 Benign neoplasms
0.951 0.049 0.000
I84.9 Unspecified haemorrhoids without complication
0.947 0.053 0.000
I20-I25 Ischaemic heart diseases
0.941 0.059 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.934 0.066 0.000
M20-M25 Other joint disorders
0.933 0.067 0.000
Z72 Problems related to lifestyle
0.929 0.071 0.000
M15-M19 Arthrosis
0.921 0.079 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.919 0.081 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.914 0.086 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.910 0.090 0.000
I50 Heart failure
0.910 0.090 0.000
Z72.0 Tobacco use
0.892 0.108 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.880 0.119 0.000
I25 Chronic ischaemic heart disease
0.867 0.133 0.000
I83 Varicose veins of lower extremities
0.856 0.144 0.000
I84.1 Internal haemorrhoids with other complications
0.856 0.144 0.000
E70-E90 Metabolic disorders
0.841 0.159 0.000
Z95.1 Presence of aortocoronary bypass graft
0.836 0.164 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.825 0.175 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.825 0.175 0.000
I50.1 Left ventricular failure
0.821 0.179 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.819 0.181 0.000
M20 Acquired deformities of fingers and toes
0.816 0.184 0.000
I84.2 Internal haemorrhoids without complication
0.815 0.185 0.000
D12.8 Rectum
0.810 0.190 0.000
Chapter XIV Diseases of the genitourinary system
0.805 0.195 0.000
M05-M14 Inflammatory polyarthropathies
0.804 0.196 0.000
M19 Other arthrosis
0.796 0.204 0.000
Z92 Personal history of medical treatment
0.794 0.206 0.000
I45 Other conduction disorders
0.793 0.207 0.000
Z96 Presence of other functional implants
0.790 0.210 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.785 0.215 0.000
D12.2 Ascending colon
0.785 0.215 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.782 0.218 0.000
Z72.1 Alcohol use
0.780 0.220 0.000
M45-M49 Spondylopathies
0.779 0.221 0.000
M25 Other joint disorders, not elsewhere classified
0.778 0.222 0.000
I25.2 Old myocardial infarction
0.777 0.223 0.000
Z13 Special screening examination for other diseases and disorders
0.774 0.226 0.000
M16 Coxarthrosis [arthrosis of hip]
0.773 0.227 0.000
M23 Internal derangement of knee
0.773 0.227 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.772 0.228 0.000
D12.3 Transverse colon
0.770 0.230 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.769 0.231 0.000
M50-M54 Other dorsopathies
0.765 0.235 0.000
I84.8 Unspecified haemorrhoids with other complications
0.762 0.238 0.000
I50.0 Congestive heart failure
0.762 0.238 0.000
Z88.8 Personal history of allergy to other drugs, medicaments and biological substances
0.761 0.239 0.000
C60-C63 Malignant neoplasms of male genital organs
0.760 0.240 0.000
I83.9 Varicose veins of lower extremities without ulcer or inflammation
0.760 0.240 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.759 0.241 0.000
Chapter VI Diseases of the nervous system
0.759 0.241 0.000
I20 Angina pectoris
0.756 0.244 0.000
Chapter VII Diseases of the eye and adnexa
0.754 0.246 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.747 0.253 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.747 0.253 0.000
D25 Leiomyoma of uterus
0.746 0.254 0.000
I34 Nonrheumatic mitral valve disorders
0.742 0.258 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.741 0.259 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.740 0.260 0.000
M17 Gonarthrosis [arthrosis of knee]
0.738 0.262 0.000
Chapter VIII Diseases of the ear and mastoid process
0.737 0.263 0.000
Chapter X Diseases of the respiratory system
0.734 0.266 0.000
Z98 Other postsurgical states
0.732 0.268 0.000
D12.5 Sigmoid colon
0.732 0.268 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.731 0.269 0.000
D17 Benign lipomatous neoplasm
0.730 0.269 0.000
E00-E07 Disorders of thyroid gland
0.724 0.276 0.000
Z95.0 Presence of cardiac pacemaker
0.724 0.276 0.000
I21 Acute myocardial infarction
0.721 0.279 0.000
Chapter XXII Codes for special purposes
0.717 0.283 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I60-I69 Cerebrovascular diseases
0.717 0.283 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.717 0.283 0.000
I05-I09 Chronic rheumatic heart diseases
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
I50.9 Heart failure, unspecified
0.717 0.283 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.716 0.284 0.000
Chapter V Mental and behavioural disorders
0.712 0.288 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.711 0.289 0.000
I88 Nonspecific lymphadenitis
0.711 0.289 0.000
I87 Other disorders of veins
0.711 0.289 0.000
I86 Varicose veins of other sites
0.711 0.289 0.000
I85 Oesophageal varices
0.711 0.289 0.000
I82 Other venous embolism and thrombosis
0.711 0.289 0.000
I81 Portal vein thrombosis
0.711 0.289 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.710 0.290 0.000
M91-M94 Chondropathies
0.710 0.290 0.000
M86-M90 Other osteopathies
0.710 0.290 0.000
M65-M68 Disorders of synovium and tendon
0.710 0.290 0.000
M60-M63 Disorders of muscles
0.710 0.290 0.000
M40-M43 Deforming dorsopathies
0.710 0.290 0.000
M00-M03 Infectious arthropathies
0.710 0.290 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.710 0.290 0.000
Chapter I Certain infectious and parasitic diseases
0.709 0.291 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.708 0.292 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.706 0.294 0.000
M19.9 Arthrosis, unspecified
0.706 0.294 0.000
Z88.5 Personal history of allergy to narcotic agent
0.702 0.298 0.000
I84.7 Unspecified thrombosed haemorrhoids
0.702 0.298 0.000
I84.5 External haemorrhoids without complication
0.702 0.298 0.000
I84.4 External haemorrhoids with other complications
0.702 0.298 0.000
I84.3 External thrombosed haemorrhoids
0.702 0.298 0.000
I84.0 Internal thrombosed haemorrhoids
0.702 0.298 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.702 0.298 0.000
D00-D09 In situ neoplasms
0.702 0.298 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.702 0.298 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.702 0.298 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.702 0.298 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.702 0.298 0.000
C64-C68 Malignant neoplasms of urinary tract
0.702 0.298 0.000
C51-C58 Malignant neoplasms of female genital organs
0.702 0.298 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.702 0.298 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.702 0.298 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.702 0.298 0.000
C15-C26 Malignant neoplasms of digestive organs
0.702 0.298 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.702 0.298 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.702 0.298 0.000
Z97 Presence of other devices
0.702 0.298 0.000
Z94 Transplanted organ and tissue status
0.702 0.298 0.000
Z93 Artificial opening status
0.702 0.298 0.000
Z89 Acquired absence of limb
0.702 0.298 0.000
Z84 Family history of other conditions
0.702 0.298 0.000
Z83 Family history of other specific disorders
0.702 0.298 0.000
Z81 Family history of mental and behavioural disorders
0.702 0.298 0.000
I25.1 Atherosclerotic heart disease
0.701 0.299 0.000
M20.1 Hallux valgus (acquired)
0.700 0.300 0.000
I73 Other peripheral vascular diseases
0.700 0.300 0.000
I80 Phlebitis and thrombophlebitis
0.698 0.302 0.000
I51 Complications and ill-defined descriptions of heart disease
0.698 0.302 0.000
Chapter XX External causes of morbidity and mortality
0.697 0.303 0.000
Z96.6 Presence of orthopaedic joint implants
0.693 0.307 0.000
Z80 Family history of malignant neoplasm
0.692 0.308 0.000
I52 Other heart disorders in diseases classified elsewhere
0.690 0.310 0.000
I49 Other cardiac arrhythmias
0.690 0.310 0.000
I48 Atrial fibrillation and flutter
0.690 0.310 0.000
I46 Cardiac arrest
0.690 0.310 0.000
I44 Atrioventricular and left bundle-branch block
0.690 0.310 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.690 0.310 0.000
I42 Cardiomyopathy
0.690 0.310 0.000
I41 Myocarditis in diseases classified elsewhere
0.690 0.310 0.000
I40 Acute myocarditis
0.690 0.310 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.690 0.310 0.000
I37 Pulmonary valve disorders
0.690 0.310 0.000
I36 Nonrheumatic tricuspid valve disorders
0.690 0.310 0.000
I35 Nonrheumatic aortic valve disorders
0.690 0.310 0.000
I33 Acute and subacute endocarditis
0.690 0.310 0.000
I32 Pericarditis in diseases classified elsewhere
0.690 0.310 0.000
I31 Other diseases of pericardium
0.690 0.310 0.000
I30 Acute pericarditis
0.690 0.310 0.000
I38 Endocarditis, valve unspecified
0.690 0.310 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.689 0.311 0.000
M70-M79 Other soft tissue disorders
0.688 0.312 0.000
Z86 Personal history of certain other diseases
0.688 0.312 0.000
Z76 Persons encountering health services in other circumstances
0.687 0.313 0.000
Z75 Problems related to medical facilities and other health care
0.687 0.313 0.000
Z74 Problems related to care-provider dependency
0.687 0.313 0.000
Z73 Problems related to life-management difficulty
0.687 0.313 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.687 0.313 0.000
Z70 Counselling related to sexual attitude, behaviour and orientation
0.687 0.313 0.000
I47 Paroxysmal tachycardia
0.686 0.313 0.000
C50-C50 Malignant neoplasm of breast
0.685 0.315 0.000
M80-M85 Disorders of bone density and structure
0.684 0.316 0.000
D36 Benign neoplasm of other and unspecified sites
0.682 0.318 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.682 0.318 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.682 0.318 0.000
D32 Benign neoplasm of meninges
0.682 0.318 0.000
D31 Benign neoplasm of eye and adnexa
0.682 0.318 0.000
D30 Benign neoplasm of urinary organs
0.682 0.318 0.000
D29 Benign neoplasm of male genital organs
0.682 0.318 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.682 0.318 0.000
D26 Other benign neoplasms of uterus
0.682 0.318 0.000
D23 Other benign neoplasms of skin
0.682 0.318 0.000
D22 Melanocytic naevi
0.682 0.318 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.682 0.318 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.682 0.318 0.000
D19 Benign neoplasm of mesothelial tissue
0.682 0.318 0.000
D18 Haemangioma and lymphangioma, any site
0.682 0.318 0.000
D16 Benign neoplasm of bone and articular cartilage
0.682 0.318 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.682 0.318 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.682 0.318 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.682 0.318 0.000
D11 Benign neoplasm of major salivary glands
0.682 0.318 0.000
D10 Benign neoplasm of mouth and pharynx
0.682 0.318 0.000
D34 Benign neoplasm of thyroid gland
0.682 0.318 0.000
D27 Benign neoplasm of ovary
0.682 0.318 0.000
D24 Benign neoplasm of breast
0.682 0.318 0.000
Z92.2 Personal history of long-term (current) use of other medicaments
0.681 0.319 0.000
Z02 Examination and encounter for administrative purposes
0.675 0.325 0.000
M06 Other rheumatoid arthritis
0.675 0.325 0.000
I24 Other acute ischaemic heart diseases
0.674 0.326 0.000
I23 Certain current complications following acute myocardial infarction
0.674 0.326 0.000
I22 Subsequent myocardial infarction
0.674 0.326 0.000
I45.1 Other and unspecified right bundle-branch block
0.672 0.328 0.000
Z88.6 Personal history of allergy to analgesic agent
0.671 0.329 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.670 0.330 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.670 0.330 0.000
Z95.4 Presence of other heart-valve replacement
0.670 0.330 0.000
Z95.3 Presence of xenogenic heart valve
0.670 0.330 0.000
Z95.2 Presence of prosthetic heart valve
0.670 0.330 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.669 0.331 0.000
M35 Other systemic involvement of connective tissue
0.669 0.331 0.000
M34 Systemic sclerosis
0.669 0.331 0.000
M33 Dermatopolymyositis
0.669 0.331 0.000
M32 Systemic lupus erythematosus
0.669 0.331 0.000
M31 Other necrotising vasculopathies
0.669 0.331 0.000
M30 Polyarteritis nodosa and related conditions
0.669 0.331 0.000
M24 Other specific joint derangements
0.669 0.331 0.000
M22 Disorders of patella
0.669 0.331 0.000
M21 Other acquired deformities of limbs
0.669 0.331 0.000
Z01.8 Other specified special examinations
0.668 0.332 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.667 0.333 0.000
Z72.9 Problem related to lifestyle, unspecified
0.666 0.334 0.000
Z72.8 Other problems related to lifestyle
0.666 0.334 0.000
Z72.6 Gambling and betting
0.666 0.334 0.000
Z72.5 High-risk sexual behaviour
0.666 0.334 0.000
Z72.4 Inappropriate diet and eating habits
0.666 0.334 0.000
Z72.3 Lack of physical exercise
0.666 0.334 0.000
Z72.2 Drug use
0.666 0.334 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.666 0.334 0.000
M18 Arthrosis of first carpometacarpal joint
0.660 0.340 0.000
M15 Polyarthrosis
0.660 0.340 0.000
D12.9 Anus and anal canal
0.659 0.341 0.000
D12.7 Rectosigmoid junction
0.659 0.341 0.000
D12.6 Colon, unspecified
0.659 0.341 0.000
D12.4 Descending colon
0.659 0.341 0.000
D12.1 Appendix
0.659 0.341 0.000
D12.0 Caecum
0.659 0.341 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.658 0.342 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.656 0.344 0.000
E50-E64 Other nutritional deficiencies
0.656 0.344 0.000
E40-E46 Malnutrition
0.656 0.344 0.000
E20-E35 Disorders of other endocrine glands
0.656 0.344 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.656 0.344 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.652 0.348 0.000
Z10 Routine general health check-up of defined subpopulation
0.652 0.348 0.000
Z04 Examination and observation for other reasons
0.652 0.348 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.652 0.348 0.000
S80-S89 Injuries to the knee and lower leg
0.650 0.350 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.650 0.350 0.000
E65-E68 Obesity and other hyperalimentation
0.650 0.350 0.000
S00-S09 Injuries to the head
0.644 0.356 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.644 0.356 0.000
I20.9 Angina pectoris, unspecified
0.641 0.359 0.000
Z88.0 Personal history of allergy to penicillin
0.638 0.362 0.000
Z90.4 Acquired absence of other parts of digestive tract
0.637 0.363 0.000
Z13.9 Special screening examination, unspecified
0.635 0.365 0.000
M16.1 Other primary coxarthrosis
0.632 0.368 0.000
Z88.9 Personal history of allergy to unspecified drugs, medicaments and biological substances
0.631 0.369 0.000
Z88.7 Personal history of allergy to serum and vaccine
0.631 0.369 0.000
Z88.4 Personal history of allergy to anaesthetic agent
0.631 0.369 0.000
Z88.3 Personal history of allergy to other anti-infective agents
0.631 0.369 0.000
Z88.2 Personal history of allergy to sulphonamides
0.631 0.369 0.000
Z88.1 Personal history of allergy to other antibiotic agents
0.629 0.371 0.000
E10-E14 Diabetes mellitus
0.628 0.372 0.000
I84.6 Residual haemorrhoidal skin tags
0.627 0.373 0.000
Z90.5 Acquired absence of kidney
0.627 0.373 0.000
M20.2 Hallux rigidus
0.626 0.374 0.000
E78.0 Pure hypercholesterolaemia
0.625 0.375 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.624 0.376 0.000
M25.4 Effusion of joint
0.624 0.376 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.623 0.377 0.000
I25.6 Silent myocardial ischaemia
0.621 0.379 0.000
I25.5 Ischaemic cardiomyopathy
0.621 0.379 0.000
I25.4 Coronary artery aneurysm
0.621 0.379 0.000
I25.3 Aneurysm of heart
0.621 0.379 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.621 0.379 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.621 0.379 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.619 0.381 0.000
M25.7 Osteophyte
0.619 0.381 0.000
Z87 Personal history of other diseases and conditions
0.619 0.381 0.000
L60-L75 Disorders of skin appendages
0.617 0.383 0.000
E86 Volume depletion
0.616 0.384 0.000
E87.1 Hypo-osmolality and hyponatraemia
0.616 0.384 0.000
I83.2 Varicose veins of lower extremities with both ulcer and inflammation
0.614 0.386 0.000
I83.1 Varicose veins of lower extremities with inflammation
0.614 0.386 0.000
I83.0 Varicose veins of lower extremities with ulcer
0.614 0.386 0.000
N30-N39 Other diseases of urinary system
0.613 0.387 0.000
M20.5 Other deformities of toe(s) (acquired)
0.612 0.387 0.000
I73.9 Peripheral vascular disease, unspecified
0.611 0.389 0.000
M16.9 Coxarthrosis, unspecified
0.610 0.390 0.000
Z60 Problems related to social environment
0.609 0.391 0.000
E78.5 Hyperlipidaemia, unspecified
0.608 0.392 0.000
Z03.5 Observation for other suspected cardiovascular diseases
0.607 0.393 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.607 0.393 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.605 0.395 0.000
M48 Other spondylopathies
0.603 0.396 0.000
C61 Malignant neoplasm of prostate
0.603 0.397 0.000
M54 Dorsalgia
0.603 0.397 0.000
S60-S69 Injuries to the wrist and hand
0.603 0.397 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.603 0.397 0.000
E88 Other metabolic disorders
0.603 0.397 0.000
E85 Amyloidosis
0.603 0.397 0.000
E84 Cystic fibrosis
0.603 0.397 0.000
E83 Disorders of mineral metabolism
0.603 0.397 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.603 0.397 0.000
E79 Disorders of purine and pyrimidine metabolism
0.603 0.397 0.000
E77 Disorders of glycoprotein metabolism
0.603 0.397 0.000
E76 Disorders of glycosaminoglycan metabolism
0.603 0.397 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.603 0.397 0.000
E74 Other disorders of carbohydrate metabolism
0.603 0.397 0.000
E73 Lactose intolerance
0.603 0.397 0.000
E72 Other disorders of amino-acid metabolism
0.603 0.397 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.603 0.397 0.000
E70 Disorders of aromatic amino-acid metabolism
0.603 0.397 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.603 0.397 0.000
D25.9 Leiomyoma of uterus, unspecified
0.600 0.400 0.000
S50-S59 Injuries to the elbow and forearm
0.599 0.401 0.000
N20-N23 Urolithiasis
0.598 0.402 0.000
H40-H42 Glaucoma
0.597 0.403 0.000
Z12 Special screening examination for neoplasms
0.596 0.403 0.000
M17.9 Gonarthrosis, unspecified
0.596 0.404 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.596 0.404 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.592 0.408 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.592 0.408 0.000
I78 Diseases of capillaries
0.592 0.408 0.000
I77 Other disorders of arteries and arterioles
0.592 0.408 0.000
I74 Arterial embolism and thrombosis
0.592 0.408 0.000
I72 Other aneurysm
0.592 0.408 0.000
I71 Aortic aneurysm and dissection
0.592 0.408 0.000
I70 Atherosclerosis
0.592 0.408 0.000
M47 Spondylosis
0.589 0.411 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.587 0.412 0.000
T79-T79 Certain early complications of trauma
0.587 0.412 0.000
T66-T78 Other and unspecified effects of external causes
0.587 0.412 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.587 0.412 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.587 0.412 0.000
T33-T35 Frostbite
0.587 0.412 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.587 0.412 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.587 0.412 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.587 0.412 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.587 0.412 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.587 0.412 0.000
T00-T07 Injuries involving multiple body regions
0.587 0.412 0.000
S90-S99 Injuries to the ankle and foot
0.587 0.412 0.000
S70-S79 Injuries to the hip and thigh
0.587 0.412 0.000
S40-S49 Injuries to the shoulder and upper arm
0.587 0.412 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.587 0.412 0.000
S20-S29 Injuries to the thorax
0.587 0.412 0.000
S10-S19 Injuries to the neck
0.587 0.412 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.585 0.415 0.000
M20.4 Other hammer toe(s) (acquired)
0.585 0.415 0.000
M20.3 Other deformity of hallux (acquired)
0.585 0.415 0.000
M20.0 Deformity of finger(s)
0.585 0.415 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.584 0.416 0.000
I34.0 Mitral (valve) insufficiency
0.583 0.417 0.000
M06.9 Rheumatoid arthritis, unspecified
0.582 0.418 0.000
M17.0 Primary gonarthrosis, bilateral
0.581 0.419 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.579 0.421 0.000
J20-J22 Other acute lower respiratory infections
0.578 0.422 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.578 0.422 0.000
N99-N99 Other disorders of the genitourinary system
0.577 0.423 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.577 0.423 0.000
N60-N64 Disorders of breast
0.577 0.423 0.000
N25-N29 Other disorders of kidney and ureter
0.577 0.423 0.000
N10-N16 Renal tubulo-interstitial diseases
0.577 0.423 0.000
N00-N08 Glomerular diseases
0.577 0.423 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.577 0.423 0.000
M14 Arthropathies in other diseases classified elsewhere
0.576 0.424 0.000
M12 Other specific arthropathies
0.576 0.424 0.000
M11 Other crystal arthropathies
0.576 0.424 0.000
M10 Gout
0.576 0.424 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.576 0.424 0.000
M08 Juvenile arthritis
0.576 0.424 0.000
M07 Psoriatic and enteropathic arthropathies
0.576 0.424 0.000
M05 Seropositive rheumatoid arthritis
0.576 0.424 0.000
N40-N51 Diseases of male genital organs
0.574 0.426 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.573 0.427 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.572 0.427 0.000
R30-R39 Symptoms and signs involving the urinary system
0.572 0.428 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.571 0.429 0.000
M19.8 Other specified arthrosis
0.571 0.429 0.000
M19.2 Other secondary arthrosis
0.571 0.429 0.000
M19.1 Posttraumatic arthrosis of other joints
0.571 0.429 0.000
M19.0 Primary arthrosis of other joints
0.571 0.429 0.000
Z92.9 Personal history of medical treatment, unspecified
0.569 0.431 0.000
Z92.8 Personal history of other medical treatment
0.569 0.431 0.000
Z92.5 Personal history of rehabilitation measures
0.569 0.431 0.000
Z92.4 Personal history of major surgery, not elsewhere classified
0.569 0.431 0.000
Z92.3 Personal history of irradiation
0.569 0.431 0.000
Z92.0 Personal history of contraception
0.569 0.431 0.000
I45.9 Conduction disorder, unspecified
0.569 0.431 0.000
I45.8 Other specified conduction disorders
0.569 0.431 0.000
I45.6 Preexcitation syndrome
0.569 0.431 0.000
I45.5 Other specified heart block
0.569 0.431 0.000
I45.4 Nonspecific intraventricular block
0.569 0.431 0.000
I45.3 Trifascicular block
0.569 0.431 0.000
I45.2 Bifascicular block
0.569 0.431 0.000
I45.0 Right fascicular block
0.569 0.431 0.000
M13 Other arthritis
0.568 0.432 0.000
Z96.9 Presence of functional implant, unspecified
0.567 0.433 0.000
Z96.8 Presence of other specified functional implants
0.567 0.433 0.000
Z96.7 Presence of other bone and tendon implants
0.567 0.433 0.000
Z96.5 Presence of tooth-root and mandibular implants
0.567 0.433 0.000
Z96.4 Presence of endocrine implants
0.567 0.433 0.000
Z96.3 Presence of artificial larynx
0.567 0.433 0.000
Z96.2 Presence of otological and audiological implants
0.567 0.433 0.000
Z96.0 Presence of urogenital implants
0.567 0.433 0.000
C79 Secondary malignant neoplasm of other sites
0.566 0.434 0.000
M23.22 Derangement of meniscus due to old tear or injury (Posterior cruciate ligament or Posterior horn of medial meniscus)
0.564 0.436 0.000
Z90.8 Acquired absence of other organs
0.563 0.437 0.000
Z90.6 Acquired absence of other parts of urinary tract
0.563 0.437 0.000
Z90.3 Acquired absence of part of stomach
0.563 0.437 0.000
Z90.2 Acquired absence of lung [part of]
0.563 0.437 0.000
Z90.0 Acquired absence of part of head and neck
0.563 0.437 0.000
I21.9 Acute myocardial infarction, unspecified
0.563 0.437 0.000
Z03.8 Observation for other suspected diseases and conditions
0.562 0.438 0.000
C80 Malignant neoplasm without specification of site
0.560 0.439 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.560 0.439 0.000
E03 Other hypothyroidism
0.559 0.441 0.000
M49 Spondylopathies in diseases classified elsewhere
0.558 0.441 0.000
M46 Other inflammatory spondylopathies
0.558 0.441 0.000
M45 Ankylosing spondylitis
0.558 0.441 0.000
Z50 Care involving use of rehabilitation procedures
0.558 0.442 0.000
M25.9 Joint disorder, unspecified
0.558 0.442 0.000
M25.8 Other specified joint disorders
0.558 0.442 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.558 0.442 0.000
M25.5 Pain in joint
0.558 0.442 0.000
M25.3 Other instability of joint
0.558 0.442 0.000
M25.2 Flail joint
0.558 0.442 0.000
M25.1 Fistula of joint
0.558 0.442 0.000
M25.0 Haemarthrosis
0.558 0.442 0.000
N84 Polyp of female genital tract
0.558 0.442 0.000
Z98.0 Intestinal bypass and anastomosis status
0.555 0.444 0.000
Z13.8 Special screening examination for other specified diseases and disorders
0.555 0.445 0.000
Z13.7 Special screening examination for congenital malformations, deformations and chromosomal abnormalities
0.555 0.445 0.000
Z13.6 Special screening examination for cardiovascular disorders
0.555 0.445 0.000
Z13.5 Special screening examination for eye and ear disorders
0.555 0.445 0.000
Z13.4 Special screening examination for certain developmental disorders in childhood
0.555 0.445 0.000
Z13.3 Special screening examination for mental and behavioural disorders
0.555 0.445 0.000
Z13.2 Special screening examination for nutritional disorders
0.555 0.445 0.000
Z13.1 Special screening examination for diabetes mellitus
0.555 0.445 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.555 0.445 0.000
M16.7 Other secondary coxarthrosis
0.554 0.446 0.000
M16.6 Other secondary coxarthrosis, bilateral
0.554 0.446 0.000
M16.5 Other posttraumatic coxarthrosis
0.554 0.446 0.000
M16.4 Posttraumatic coxarthrosis, bilateral
0.554 0.446 0.000
M16.3 Other dysplastic coxarthrosis
0.554 0.446 0.000
M16.2 Coxarthrosis resulting from dysplasia, bilateral
0.554 0.446 0.000
M16.0 Primary coxarthrosis, bilateral
0.554 0.446 0.000
M23.9 Internal derangement of knee, unspecified
0.554 0.446 0.000
M23.8 Other internal derangements of knee
0.554 0.446 0.000
M23.6 Other spontaneous disruption of ligament(s) of knee
0.554 0.446 0.000
M23.5 Chronic instability of knee
0.554 0.446 0.000
M23.4 Loose body in knee
0.554 0.446 0.000
M23.3 Other meniscus derangements
0.554 0.446 0.000
M23.1 Discoid meniscus (congenital)
0.554 0.446 0.000
M23.0 Cystic meniscus
0.554 0.446 0.000
C44 Other malignant neoplasms of skin
0.554 0.446 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.553 0.446 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.553 0.447 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.553 0.447 0.000
Z65 Problems related to other psychosocial circumstances
0.553 0.447 0.000
Z64 Problems related to certain psychosocial circumstances
0.553 0.447 0.000
Z63 Other problems related to primary support group, including family circumstances
0.553 0.447 0.000
Z62 Other problems related to upbringing
0.553 0.447 0.000
Z61 Problems related to negative life events in childhood
0.553 0.447 0.000
Z59 Problems related to housing and economic circumstances
0.553 0.447 0.000
Z58 Problems related to physical environment
0.553 0.447 0.000
Z57 Occupational exposure to risk-factors
0.553 0.447 0.000
Z56 Problems related to employment and unemployment
0.553 0.447 0.000
Z55 Problems related to education and literacy
0.553 0.447 0.000
I10-I15 Hypertensive diseases
0.552 0.448 0.000
Z01.9 Special examination, unspecified
0.551 0.449 0.000
Z01.7 Laboratory examination
0.551 0.449 0.000
Z01.6 Radiological examination, not elsewhere classified
0.551 0.449 0.000
Z01.5 Diagnostic skin and sensitisation tests
0.551 0.449 0.000
Z01.4 Gynaecological examination (general)(routine)
0.551 0.449 0.000
Z01.3 Examination of blood pressure
0.551 0.449 0.000
Z01.2 Dental examination
0.551 0.449 0.000
Z01.1 Examination of ears and hearing
0.551 0.449 0.000
Z01.0 Examination of eyes and vision
0.551 0.449 0.000
J90-J94 Other diseases of pleura
0.550 0.450 0.000
H90-H95 Other disorders of ear
0.549 0.451 0.000
M53 Other dorsopathies, not elsewhere classified
0.548 0.451 0.000
M51 Other intervertebral disk disorders
0.548 0.451 0.000
M50 Cervical disk disorders
0.548 0.451 0.000
G40-G47 Episodic and paroxysmal disorders
0.547 0.453 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.545 0.455 0.000
C62 Malignant neoplasm of testis
0.545 0.455 0.000
C60 Malignant neoplasm of penis
0.545 0.455 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.544 0.455 0.000
L50-L54 Urticaria and erythema
0.544 0.455 0.000
L40-L45 Papulosquamous disorders
0.544 0.455 0.000
L20-L30 Dermatitis and eczema
0.544 0.455 0.000
L10-L14 Bullous disorders
0.544 0.455 0.000
G90-G99 Other disorders of the nervous system
0.544 0.456 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.544 0.456 0.000
G70-G73 Diseases of myoneural junction and muscle
0.544 0.456 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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