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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs157079
log Bayes Factor = 29.5092
Chromosome 10   position 106,058,778  (GRCh37) Explore rs157079 on Ensembl!
Variant rs157079 is part of Cluster X0077

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
I25 Chronic ischaemic heart disease
1.000 0.000 0.000
I20-I25 Ischaemic heart diseases
1.000 0.000 0.000
Chapter IX Diseases of the circulatory system
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
I10 Essential (primary) hypertension
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
I10-I15 Hypertensive diseases
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
E70-E90 Metabolic disorders
0.998 0.002 0.000
R50-R69 General symptoms and signs
0.998 0.002 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.997 0.003 0.000
I25.1 Atherosclerotic heart disease
0.997 0.003 0.000
I20 Angina pectoris
0.996 0.004 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.996 0.004 0.000
I25.2 Old myocardial infarction
0.992 0.008 0.000
Chapter XXI Factors influencing health status and contact with health services
0.992 0.008 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.991 0.009 0.000
I60-I69 Cerebrovascular diseases
0.991 0.009 0.000
Z86 Personal history of certain other diseases
0.991 0.009 0.000
Z86.7 Personal history of diseases of the circulatory system
0.990 0.010 0.000
I20.9 Angina pectoris, unspecified
0.985 0.015 0.000
I21 Acute myocardial infarction
0.983 0.017 0.000
I30-I52 Other forms of heart disease
0.982 0.018 0.000
E78.0 Pure hypercholesterolaemia
0.982 0.018 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.979 0.021 0.000
E10-E14 Diabetes mellitus
0.979 0.021 0.000
M05-M14 Inflammatory polyarthropathies
0.978 0.022 0.000
M20-M25 Other joint disorders
0.974 0.026 0.000
E78.5 Hyperlipidaemia, unspecified
0.973 0.027 0.000
Chapter XI Diseases of the digestive system
0.971 0.029 0.000
R51 Headache
0.965 0.035 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.964 0.036 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.963 0.037 0.000
E14 Unspecified diabetes mellitus
0.958 0.042 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.957 0.043 0.000
I21.9 Acute myocardial infarction, unspecified
0.957 0.043 0.000
Chapter VII Diseases of the eye and adnexa
0.955 0.045 0.000
M06 Other rheumatoid arthritis
0.947 0.053 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.945 0.055 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.944 0.056 0.000
I80 Phlebitis and thrombophlebitis
0.944 0.056 0.000
E14.9 Without complications
0.944 0.056 0.000
R55 Syncope and collapse
0.942 0.058 0.000
H02 Other disorders of eyelid
0.940 0.060 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.938 0.062 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.937 0.063 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.936 0.064 0.000
I80.2 Phlebitis and thrombophlebitis of other deep vessels of lower extremities
0.932 0.068 0.000
K22 Other diseases of oesophagus
0.930 0.070 0.000
I51 Complications and ill-defined descriptions of heart disease
0.929 0.071 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.928 0.072 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.928 0.072 0.000
E65-E68 Obesity and other hyperalimentation
0.927 0.073 0.000
M25 Other joint disorders, not elsewhere classified
0.920 0.080 0.000
M06.9 Rheumatoid arthritis, unspecified
0.914 0.086 0.000
K22.1 Ulcer of oesophagus
0.912 0.088 0.000
R47-R49 Symptoms and signs involving speech and voice
0.910 0.090 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.906 0.094 0.000
Z95.0 Presence of cardiac pacemaker
0.904 0.096 0.000
Z87 Personal history of other diseases and conditions
0.897 0.103 0.000
I69 Sequelae of cerebrovascular disease
0.896 0.104 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.895 0.105 0.000
E86 Volume depletion
0.893 0.107 0.000
I20.0 Unstable angina
0.890 0.110 0.000
Chapter II Neoplasms
0.889 0.111 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.888 0.112 0.000
M23 Internal derangement of knee
0.888 0.112 0.000
I34 Nonrheumatic mitral valve disorders
0.886 0.114 0.000
R15 Faecal incontinence
0.883 0.117 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.882 0.118 0.000
H02.8 Other specified disorders of eyelid
0.880 0.120 0.000
S60-S69 Injuries to the wrist and hand
0.878 0.122 0.000
E66 Obesity
0.876 0.124 0.000
R19.0 Intra-abdominal and pelvic swelling, mass and lump
0.873 0.127 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.871 0.129 0.000
Chapter XX External causes of morbidity and mortality
0.868 0.132 0.000
I67 Other cerebrovascular diseases
0.868 0.132 0.000
Z95.1 Presence of aortocoronary bypass graft
0.865 0.135 0.000
I51.7 Cardiomegaly
0.864 0.136 0.000
R50 Fever of unknown origin
0.864 0.136 0.000
M23.2 Derangement of meniscus due to old tear or injury
0.863 0.137 0.000
H02.4 Ptosis of eyelid
0.858 0.142 0.000
E66.8 Other obesity
0.857 0.143 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.856 0.144 0.000
I49 Other cardiac arrhythmias
0.856 0.144 0.000
Chapter VIII Diseases of the ear and mastoid process
0.854 0.146 0.000
H02.0 Entropion and trichiasis of eyelid
0.853 0.147 0.000
K20 Oesophagitis
0.852 0.148 0.000
Chapter VI Diseases of the nervous system
0.849 0.151 0.000
M25.5 Pain in joint
0.848 0.152 0.000
M06.90 Rheumatoid arthritis, unspecified (Multiple sites)
0.847 0.153 0.000
S80-S89 Injuries to the knee and lower leg
0.847 0.153 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.846 0.154 0.000
I50 Heart failure
0.842 0.158 0.000
R47 Speech disturbances, not elsewhere classified
0.842 0.158 0.000
Z87.1 Personal history of diseases of the digestive system
0.840 0.160 0.000
D10-D36 Benign neoplasms
0.840 0.160 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.839 0.160 0.000
I22 Subsequent myocardial infarction
0.835 0.165 0.000
Z86.1 Personal history of infectious and parasitic diseases
0.832 0.168 0.000
K25 Gastric ulcer
0.831 0.169 0.000
I69.4 Sequelae of stroke, not specified as haemorrhage or infarction
0.828 0.172 0.000
R53 Malaise and fatigue
0.827 0.173 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.826 0.174 0.000
Z89 Acquired absence of limb
0.825 0.175 0.000
Z86.4 Personal history of psychoactive substance abuse
0.823 0.177 0.000
M23.23 Derangement of meniscus due to old tear or injury (Medial collateral ligament or Other and unspecified medial meniscus)
0.823 0.177 0.000
M11 Other crystal arthropathies
0.822 0.178 0.000
K40-K46 Hernia
0.821 0.179 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.821 0.179 0.000
K01 Embedded and impacted teeth
0.819 0.181 0.000
R60 Oedema, not elsewhere classified
0.817 0.183 0.000
K22.2 Oesophageal obstruction
0.815 0.185 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.814 0.186 0.000
M40-M43 Deforming dorsopathies
0.811 0.189 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.810 0.190 0.000
Z86.0 Personal history of other neoplasms
0.809 0.191 0.000
E13 Other specified diabetes mellitus
0.807 0.193 0.000
E10 Insulin-dependent diabetes mellitus
0.803 0.197 0.000
R52 Pain, not elsewhere classified
0.802 0.198 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.801 0.199 0.000
S20-S29 Injuries to the thorax
0.797 0.203 0.000
T66-T78 Other and unspecified effects of external causes
0.797 0.203 0.000
E20-E35 Disorders of other endocrine glands
0.795 0.205 0.000
R06 Abnormalities of breathing
0.795 0.205 0.000
I34.0 Mitral (valve) insufficiency
0.795 0.205 0.000
M24 Other specific joint derangements
0.794 0.206 0.000
I21.4 Acute subendocardial myocardial infarction
0.793 0.207 0.000
K11 Diseases of salivary glands
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.792 0.208 0.000
Chapter X Diseases of the respiratory system
0.790 0.210 0.000
M31 Other necrotising vasculopathies
0.790 0.210 0.000
S50-S59 Injuries to the elbow and forearm
0.789 0.211 0.000
L97 Ulcer of lower limb, not elsewhere classified
0.789 0.211 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.788 0.212 0.000
Z95.9 Presence of cardiac and vascular implant and graft, unspecified
0.788 0.212 0.000
M22 Disorders of patella
0.787 0.213 0.000
M06.99 Rheumatoid arthritis, unspecified (Site unspecified)
0.786 0.214 0.000
I20.1 Angina pectoris with documented spasm
0.786 0.214 0.000
M25.56 Pain in joint (Lower leg)
0.785 0.215 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.784 0.216 0.000
R47.8 Other and unspecified speech disturbances
0.783 0.217 0.000
R50.9 Fever, unspecified
0.782 0.218 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.781 0.219 0.000
D17 Benign lipomatous neoplasm
0.780 0.220 0.000
M23.25 Derangement of meniscus due to old tear or injury (Posterior horn of lateral meniscus)
0.779 0.221 0.000
K22.8 Other specified diseases of oesophagus
0.777 0.223 0.000
I20.8 Other forms of angina pectoris
0.776 0.224 0.000
Chapter XIV Diseases of the genitourinary system
0.775 0.225 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.774 0.226 0.000
L03 Cellulitis
0.773 0.227 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.773 0.227 0.000
I11 Hypertensive heart disease
0.771 0.229 0.000
I60 Subarachnoid haemorrhage
0.768 0.232 0.000
K07 Dentofacial anomalies [including malocclusion]
0.767 0.233 0.000
I21.1 Acute transmural myocardial infarction of inferior wall
0.767 0.233 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.766 0.234 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.766 0.234 0.000
Chapter XXII Codes for special purposes
0.764 0.236 0.000
Z87.8 Personal history of other specified conditions
0.764 0.236 0.000
M06.0 Seronegative rheumatoid arthritis
0.764 0.236 0.000
M65-M68 Disorders of synovium and tendon
0.763 0.237 0.000
N20-N23 Urolithiasis
0.763 0.237 0.000
R19.4 Change in bowel habit
0.763 0.237 0.000
E40-E46 Malnutrition
0.762 0.238 0.000
R05 Cough
0.762 0.238 0.000
M10 Gout
0.761 0.239 0.000
R63 Symptoms and signs concerning food and fluid intake
0.760 0.240 0.000
E00-E07 Disorders of thyroid gland
0.760 0.240 0.000
E78.9 Disorder of lipoprotein metabolism, unspecified
0.758 0.242 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.758 0.242 0.000
E89 Postprocedural endocrine and metabolic disorders, not elsewhere classified
0.758 0.242 0.000
N23 Unspecified renal colic
0.757 0.243 0.000
R04 Haemorrhage from respiratory passages
0.757 0.243 0.000
D00-D09 In situ neoplasms
0.757 0.243 0.000
M07 Psoriatic and enteropathic arthropathies
0.755 0.245 0.000
J09-J18 Influenza and pneumonia
0.754 0.246 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.754 0.246 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.753 0.247 0.000
I12 Hypertensive renal disease
0.753 0.247 0.000
M00-M03 Infectious arthropathies
0.751 0.249 0.000
K12 Stomatitis and related lesions
0.750 0.250 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.750 0.250 0.000
R61 Hyperhidrosis
0.750 0.250 0.000
I67.8 Other specified cerebrovascular diseases
0.749 0.251 0.000
E50-E64 Other nutritional deficiencies
0.748 0.252 0.000
Z99.2 Dependence on renal dialysis
0.747 0.253 0.000
M25.51 Pain in joint (Shoulder region)
0.747 0.253 0.000
K14 Diseases of tongue
0.746 0.254 0.000
L60-L75 Disorders of skin appendages
0.746 0.254 0.000
R02 Gangrene, not elsewhere classified
0.745 0.255 0.000
L84 Corns and callosities
0.745 0.255 0.000
H02.6 Xanthelasma of eyelid
0.745 0.255 0.000
I45 Other conduction disorders
0.744 0.255 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.743 0.257 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
H05 Disorders of orbit
0.742 0.258 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.741 0.259 0.000
D23 Other benign neoplasms of skin
0.741 0.259 0.000
I49.3 Ventricular premature depolarisation
0.738 0.262 0.000
I25.5 Ischaemic cardiomyopathy
0.737 0.263 0.000
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts
0.737 0.263 0.000
I42 Cardiomyopathy
0.735 0.265 0.000
K40 Inguinal hernia
0.735 0.265 0.000
K01.1 Impacted teeth
0.734 0.266 0.000
O60-O75 Complications of labour and delivery
0.733 0.267 0.000
I44 Atrioventricular and left bundle-branch block
0.732 0.268 0.000
S80 Superficial injury of lower leg
0.731 0.269 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.730 0.270 0.000
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities
0.729 0.271 0.000
H55-H59 Other disorders of eye and adnexa
0.729 0.271 0.000
I51.9 Heart disease, unspecified
0.728 0.272 0.000
H65-H75 Diseases of middle ear and mastoid
0.727 0.273 0.000
I50.9 Heart failure, unspecified
0.727 0.273 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.726 0.274 0.000
Z86.2 Personal history of diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.726 0.274 0.000
M25.6 Stiffness of joint, not elsewhere classified
0.726 0.274 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.725 0.275 0.000
I51.8 Other ill-defined heart diseases
0.724 0.276 0.000
M23.20 Derangement of meniscus due to old tear or injury (Multiple sites)
0.723 0.277 0.000
H02.3 Blepharochalasis
0.722 0.278 0.000
K90-K93 Other diseases of the digestive system
0.721 0.279 0.000
I85 Oesophageal varices
0.721 0.279 0.000
R59 Enlarged lymph nodes
0.720 0.280 0.000
M80-M85 Disorders of bone density and structure
0.718 0.282 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.717 0.282 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.717 0.283 0.000
I25.6 Silent myocardial ischaemia
0.717 0.283 0.000
I25.4 Coronary artery aneurysm
0.717 0.283 0.000
I25.3 Aneurysm of heart
0.717 0.283 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.717 0.283 0.000
I23 Certain current complications following acute myocardial infarction
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
I15 Secondary hypertension
0.717 0.283 0.000
I13 Hypertensive heart and renal disease
0.717 0.283 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.717 0.283 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.716 0.284 0.000
E85 Amyloidosis
0.716 0.284 0.000
E84 Cystic fibrosis
0.716 0.284 0.000
E79 Disorders of purine and pyrimidine metabolism
0.716 0.284 0.000
E77 Disorders of glycoprotein metabolism
0.716 0.284 0.000
E76 Disorders of glycosaminoglycan metabolism
0.716 0.284 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.716 0.284 0.000
E74 Other disorders of carbohydrate metabolism
0.716 0.284 0.000
E73 Lactose intolerance
0.716 0.284 0.000
E72 Other disorders of amino-acid metabolism
0.716 0.284 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.716 0.284 0.000
E70 Disorders of aromatic amino-acid metabolism
0.716 0.284 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.716 0.284 0.000
K50-K52 Noninfective enteritis and colitis
0.716 0.284 0.000
R68 Other general symptoms and signs
0.715 0.284 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.715 0.284 0.000
R62 Lack of expected normal physiological development
0.715 0.284 0.000
R57 Shock, not elsewhere classified
0.715 0.284 0.000
R64 Cachexia
0.715 0.284 0.000
R58 Haemorrhage, not elsewhere classified
0.715 0.284 0.000
H43-H45 Disorders of vitreous body and globe
0.715 0.285 0.000
I61 Intracerebral haemorrhage
0.715 0.285 0.000
E78.8 Other disorders of lipoprotein metabolism
0.715 0.285 0.000
E78.6 Lipoprotein deficiency
0.715 0.285 0.000
E78.4 Other hyperlipidaemia
0.715 0.285 0.000
E78.3 Hyperchylomicronaemia
0.715 0.285 0.000
E78.2 Mixed hyperlipidaemia
0.715 0.285 0.000
E78.1 Pure hyperglyceridaemia
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
E88 Other metabolic disorders
0.714 0.286 0.000
T79-T79 Certain early complications of trauma
0.714 0.286 0.000
T33-T35 Frostbite
0.714 0.286 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.714 0.286 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.714 0.286 0.000
T00-T07 Injuries involving multiple body regions
0.714 0.286 0.000
S10-S19 Injuries to the neck
0.714 0.286 0.000
I87 Other disorders of veins
0.714 0.286 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.712 0.288 0.000
Z84 Family history of other conditions
0.711 0.289 0.000
Z81 Family history of mental and behavioural disorders
0.711 0.289 0.000
I68 Cerebrovascular disorders in diseases classified elsewhere
0.710 0.290 0.000
I66 Occlusion and stenosis of cerebral arteries, not resulting in cerebral infarction
0.710 0.290 0.000
I62 Other nontraumatic intracranial haemorrhage
0.710 0.290 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.710 0.290 0.000
M11.2 Other chondrocalcinosis
0.710 0.290 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.710 0.290 0.000
M86-M90 Other osteopathies
0.708 0.292 0.000
I86 Varicose veins of other sites
0.706 0.293 0.000
H02.5 Other disorders affecting eyelid function
0.706 0.293 0.000
M05 Seropositive rheumatoid arthritis
0.706 0.293 0.000
K22.4 Dyskinesia of oesophagus
0.706 0.294 0.000
M25.7 Osteophyte
0.705 0.295 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.705 0.295 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.705 0.295 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.705 0.295 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.705 0.295 0.000
L40-L45 Papulosquamous disorders
0.705 0.295 0.000
K05 Gingivitis and periodontal diseases
0.705 0.295 0.000
I52 Other heart disorders in diseases classified elsewhere
0.704 0.296 0.000
I48 Atrial fibrillation and flutter
0.704 0.296 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.704 0.296 0.000
I41 Myocarditis in diseases classified elsewhere
0.704 0.296 0.000
I40 Acute myocarditis
0.704 0.296 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.704 0.296 0.000
I37 Pulmonary valve disorders
0.704 0.296 0.000
I36 Nonrheumatic tricuspid valve disorders
0.704 0.296 0.000
I33 Acute and subacute endocarditis
0.704 0.296 0.000
I32 Pericarditis in diseases classified elsewhere
0.704 0.296 0.000
I30 Acute pericarditis
0.704 0.296 0.000
H10-H13 Disorders of conjunctiva
0.704 0.296 0.000
V20-V29 Motorcycle rider injured in transport accident
0.704 0.296 0.000
M06.96 Rheumatoid arthritis, unspecified (Lower leg)
0.704 0.296 0.000
G90-G99 Other disorders of the nervous system
0.704 0.296 0.000
K04 Diseases of pulp and periapical tissues
0.703 0.297 0.000
I05-I09 Chronic rheumatic heart diseases
0.703 0.297 0.000
L50-L54 Urticaria and erythema
0.702 0.298 0.000
Z95.3 Presence of xenogenic heart valve
0.702 0.298 0.000
E12 Malnutrition-related diabetes mellitus
0.702 0.298 0.000
S67 Crushing injury of wrist and hand
0.701 0.299 0.000
M14 Arthropathies in other diseases classified elsewhere
0.701 0.299 0.000
M12 Other specific arthropathies
0.701 0.299 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.701 0.299 0.000
M08 Juvenile arthritis
0.701 0.299 0.000
R11 Nausea and vomiting
0.700 0.300 0.000
D60-D64 Aplastic and other anaemias
0.700 0.300 0.000
H02.1 Ectropion of eyelid
0.700 0.300 0.000
I82 Other venous embolism and thrombosis
0.699 0.300 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.699 0.301 0.000
J18 Pneumonia, organism unspecified
0.699 0.301 0.000
I67.9 Cerebrovascular disease, unspecified
0.698 0.302 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.698 0.302 0.000
M34 Systemic sclerosis
0.698 0.302 0.000
M33 Dermatopolymyositis
0.698 0.302 0.000
M32 Systemic lupus erythematosus
0.698 0.302 0.000
M30 Polyarteritis nodosa and related conditions
0.698 0.302 0.000
M21 Other acquired deformities of limbs
0.698 0.302 0.000
R01 Cardiac murmurs and other cardiac sounds
0.698 0.302 0.000
Z94 Transplanted organ and tissue status
0.697 0.302 0.000
K08 Other disorders of teeth and supporting structures
0.697 0.303 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.696 0.304 0.000
M25.4 Effusion of joint
0.695 0.304 0.000
Z71 Persons encountering health services for other counselling and medical advice, not elsewhere classified
0.695 0.305 0.000
Z99.3 Dependence on wheelchair
0.695 0.305 0.000
I34.1 Mitral (valve) prolapse
0.694 0.306 0.000
Z93 Artificial opening status
0.693 0.307 0.000
K22.9 Disease of oesophagus, unspecified
0.693 0.307 0.000
S70-S79 Injuries to the hip and thigh
0.693 0.307 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.693 0.307 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.691 0.309 0.000
I88 Nonspecific lymphadenitis
0.691 0.309 0.000
I81 Portal vein thrombosis
0.691 0.309 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.691 0.309 0.000
H30-H36 Disorders of choroid and retina
0.690 0.310 0.000
R14 Flatulence and related conditions
0.690 0.310 0.000
N10-N16 Renal tubulo-interstitial diseases
0.690 0.310 0.000
S64 Injury of nerves at wrist and hand level
0.689 0.311 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.689 0.311 0.000
W20-W49 Exposure to inanimate mechanical forces
0.688 0.312 0.000
R13 Dysphagia
0.688 0.312 0.000
K25.3 Acute without haemorrhage or perforation
0.688 0.312 0.000
M06.97 Rheumatoid arthritis, unspecified (Ankle and foot)
0.687 0.312 0.000
T86 Failure and rejection of transplanted organs and tissues
0.687 0.313 0.000
E14.8 With unspecified complications
0.687 0.313 0.000
E14.7 With multiple complications
0.687 0.313 0.000
E14.6 With other specified complications
0.687 0.313 0.000
E14.5 With peripheral circulatory complications
0.687 0.313 0.000
E14.4 With neurological complications
0.687 0.313 0.000
E14.3 With ophthalmic complications
0.687 0.313 0.000
E14.2 Withrenal complications
0.687 0.313 0.000
E14.1 With ketoacidosis
0.687 0.313 0.000
E14.0 With coma
0.687 0.313 0.000
L10-L14 Bullous disorders
0.686 0.313 0.000
T43.2 Other and unspecified antidepressants
0.685 0.314 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.685 0.315 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.685 0.315 0.000
Z99.1 Dependence on respirator
0.685 0.315 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.685 0.315 0.000
E13.9 Without complications
0.684 0.316 0.000
I80.3 Phlebitis and thrombophlebitis of lower extremities, unspecified
0.684 0.316 0.000
L20-L30 Dermatitis and eczema
0.683 0.317 0.000
Z95.2 Presence of prosthetic heart valve
0.682 0.318 0.000
K35-K38 Diseases of appendix
0.682 0.318 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.681 0.319 0.000
L81 Other disorders of pigmentation
0.680 0.320 0.000
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium
0.679 0.321 0.000
D35.2 Pituitary gland
0.679 0.321 0.000
M35 Other systemic involvement of connective tissue
0.679 0.321 0.000
M06.8 Other specified rheumatoid arthritis
0.679 0.321 0.000
M06.4 Inflammatory polyarthropathy
0.679 0.321 0.000
M06.3 Rheumatoid nodule
0.679 0.321 0.000
M06.2 Rheumatoid bursitis
0.679 0.321 0.000
M06.1 Adult-onset Still's disease
0.679 0.321 0.000
M43 Other deforming dorsopathies
0.678 0.321 0.000
M23.24 Derangement of meniscus due to old tear or injury (Lateral collateral ligament or Anterior horn of lateral meniscus)
0.678 0.322 0.000
E10.9 Without complications
0.677 0.323 0.000
H06 Disorders of lachrymal system and orbit in diseases classified elsewhere
0.677 0.323 0.000
H03 Disorders of eyelid in diseases classified elsewhere
0.677 0.323 0.000
I80.9 Phlebitis and thrombophlebitis of unspecified site
0.677 0.323 0.000
I80.8 Phlebitis and thrombophlebitis of other sites
0.677 0.323 0.000
I80.0 Phlebitis and thrombophlebitis of superficial vessels of lower extremities
0.677 0.323 0.000
Z89.4 Acquired absence of foot and ankle
0.676 0.324 0.000
I46 Cardiac arrest
0.676 0.324 0.000
G40-G47 Episodic and paroxysmal disorders
0.675 0.325 0.000
R60.0 Localised oedema
0.675 0.325 0.000
H02.7 Other degenerative disorders of eyelid and periocular area
0.674 0.326 0.000
H02.2 Lagophthalmos
0.674 0.326 0.000
S60 Superficial injury of wrist and hand
0.674 0.326 0.000
S61 Open wound of wrist and hand
0.673 0.327 0.000
I63 Cerebral infarction
0.672 0.328 0.000
D29 Benign neoplasm of male genital organs
0.672 0.328 0.000
I49.0 Ventricular fibrillation and flutter
0.672 0.328 0.000
K10 Other diseases of jaws
0.672 0.328 0.000
K09 Cysts of oral region, not elsewhere classified
0.672 0.328 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.672 0.328 0.000
K03 Other diseases of hard tissues of teeth
0.672 0.328 0.000
K00 Disorders of tooth development and eruption
0.672 0.328 0.000
K28 Gastrojejunal ulcer
0.671 0.329 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.671 0.329 0.000
Z85 Personal history of malignant neoplasm
0.671 0.329 0.000
D11 Benign neoplasm of major salivary glands
0.670 0.330 0.000
R49 Voice disturbances
0.669 0.331 0.000
L03.2 Cellulitis of face
0.669 0.331 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.668 0.331 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.668 0.332 0.000
R09.8 Other specified symptoms and signs involving the circulatory and respiratory systems
0.668 0.332 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.668 0.332 0.000
E83 Disorders of mineral metabolism
0.667 0.332 0.000
K22.5 Diverticulum of oesophagus, acquired
0.667 0.333 0.000
K22.3 Perforation of oesophagus
0.667 0.333 0.000
K22.0 Achalasia of cardia
0.667 0.333 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.666 0.333 0.000
Z74 Problems related to care-provider dependency
0.666 0.334 0.000
I51.6 Cardiovascular disease, unspecified
0.666 0.334 0.000
I51.5 Myocardial degeneration
0.666 0.334 0.000
I51.4 Myocarditis, unspecified
0.666 0.334 0.000
I51.3 Intracardiac thrombosis, not elsewhere classified
0.666 0.334 0.000
I51.2 Rupture of papillary muscle, not elsewhere classified
0.666 0.334 0.000
I51.1 Rupture of chordae tendineae, not elsewhere classified
0.666 0.334 0.000
I51.0 Cardiac septal defect, acquired
0.666 0.334 0.000
E67 Other hyperalimentation
0.665 0.335 0.000
E68 Sequelae of hyperalimentation
0.665 0.335 0.000
E65 Localised adiposity
0.665 0.335 0.000
K40.2 Bilateral inguinal hernia, without obstruction or gangrene
0.665 0.335 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.664 0.336 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.664 0.336 0.000
Z80 Family history of malignant neoplasm
0.664 0.336 0.000
Z86.3 Personal history of endocrine, nutritional and metabolic diseases
0.663 0.337 0.000
K13 Other diseases of lip and oral mucosa
0.663 0.337 0.000
H00 Hordeolum and chalazion
0.661 0.338 0.000
R47.1 Dysarthria and anarthria
0.661 0.339 0.000
L03.3 Cellulitis of trunk
0.660 0.340 0.000
M25.9 Joint disorder, unspecified
0.660 0.340 0.000
M25.8 Other specified joint disorders
0.660 0.340 0.000
M25.3 Other instability of joint
0.660 0.340 0.000
M25.2 Flail joint
0.660 0.340 0.000
M25.1 Fistula of joint
0.660 0.340 0.000
M25.0 Haemarthrosis
0.660 0.340 0.000
D23.1 Skin of eyelid, including canthus
0.659 0.341 0.000
R52.1 Chronic intractable pain
0.659 0.341 0.000
M31.6 Other giant cell arteritis
0.658 0.342 0.000
J60-J70 Lung diseases due to external agents
0.658 0.342 0.000
L60 Nail disorders
0.657 0.343 0.000
R04.0 Epistaxis
0.657 0.343 0.000
C51-C58 Malignant neoplasms of female genital organs
0.656 0.343 0.000
H01 Other inflammation of eyelid
0.656 0.344 0.000
M06.98 Rheumatoid arthritis, unspecified (Other)
0.655 0.345 0.000
M06.95 Rheumatoid arthritis, unspecified (Pelvic region and thigh)
0.655 0.345 0.000
M06.94 Rheumatoid arthritis, unspecified (Hand)
0.655 0.345 0.000
M06.93 Rheumatoid arthritis, unspecified (Forearm)
0.655 0.345 0.000
M06.92 Rheumatoid arthritis, unspecified (Upper arm)
0.655 0.345 0.000
M06.91 Rheumatoid arthritis, unspecified (Shoulder region)
0.655 0.345 0.000
R06.0 Dyspnoea
0.655 0.345 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.654 0.346 0.000
D22 Melanocytic naevi
0.654 0.346 0.000
T78 Adverse effects, not elsewhere classified
0.654 0.346 0.000
K43 Ventral hernia
0.654 0.346 0.000
M22.4 Chondromalacia patellae
0.654 0.346 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.654 0.346 0.000
I50.0 Congestive heart failure
0.654 0.346 0.000
M45-M49 Spondylopathies
0.653 0.346 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.653 0.347 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.652 0.348 0.000
D35.0 Adrenal gland
0.651 0.348 0.000
M25.50 Pain in joint (Multiple sites)
0.651 0.349 0.000
I49.5 Sick sinus syndrome
0.651 0.349 0.000
K50 Crohn's disease [regional enteritis]
0.649 0.351 0.000
D34 Benign neoplasm of thyroid gland
0.649 0.351 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.648 0.352 0.000
H02.9 Disorder of eyelid, unspecified
0.647 0.353 0.000
D17.2 Benign lipomatous neoplasm of skin and subcutaneous tissue of limbs
0.646 0.354 0.000
K07.6 Temporomandibular joint disorders
0.646 0.354 0.000
O75 Other complications of labour and delivery, not elsewhere classified
0.644 0.356 0.000
Z87.6 Personal history of certain conditions arising in the perinatal period
0.643 0.357 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.642 0.358 0.000
I69.8 Sequelae of other and unspecified cerebrovascular diseases
0.642 0.358 0.000
I69.2 Sequelae of other nontraumatic intracranial haemorrhage
0.642 0.358 0.000
I69.1 Sequelae of intracerebral haemorrhage
0.642 0.358 0.000
I69.0 Sequelae of subarachnoid haemorrhage
0.642 0.358 0.000
R19.6 Halitosis
0.642 0.358 0.000
R19.3 Abdominal rigidity
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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