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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs1639114
log Bayes Factor = 20.5335
Chromosome 6   position 31,219,224  (GRCh37) Explore rs1639114 on Ensembl!

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
1.000 0.000 0.000
C44 Other malignant neoplasms of skin
0.999 0.001 0.000
Chapter IX Diseases of the circulatory system
0.999 0.001 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.999 0.001 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.999 0.001 0.000
Chapter XI Diseases of the digestive system
0.998 0.002 0.000
C44.3 Skin of other and unspecified parts of face
0.997 0.003 0.000
I20-I25 Ischaemic heart diseases
0.996 0.004 0.000
D10-D36 Benign neoplasms
0.996 0.004 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.994 0.006 0.000
E00-E07 Disorders of thyroid gland
0.994 0.006 0.000
E03 Other hypothyroidism
0.992 0.008 0.000
E03.9 Hypothyroidism, unspecified
0.991 0.009 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.991 0.009 0.000
S60-S69 Injuries to the wrist and hand
0.990 0.010 0.000
N20-N23 Urolithiasis
0.990 0.010 0.000
N17-N19 Renal failure
0.989 0.011 0.000
Chapter XX External causes of morbidity and mortality
0.984 0.016 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.979 0.021 0.000
S61 Open wound of wrist and hand
0.978 0.022 0.000
N20 Calculus of kidney and ureter
0.977 0.023 0.000
Chapter V Mental and behavioural disorders
0.977 0.023 0.000
Chapter XXI Factors influencing health status and contact with health services
0.975 0.025 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.973 0.027 0.000
N19 Unspecified renal failure
0.973 0.027 0.000
I30-I52 Other forms of heart disease
0.970 0.030 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.968 0.032 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.967 0.033 0.000
D23 Other benign neoplasms of skin
0.967 0.033 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.966 0.034 0.000
E20-E35 Disorders of other endocrine glands
0.966 0.034 0.000
I25 Chronic ischaemic heart disease
0.961 0.039 0.000
H40-H42 Glaucoma
0.960 0.040 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.956 0.044 0.000
S61.0 Open wound of finger(s) without damage to nail
0.954 0.046 0.000
I20 Angina pectoris
0.950 0.050 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.949 0.051 0.000
K04 Diseases of pulp and periapical tissues
0.945 0.055 0.000
H40 Glaucoma
0.944 0.056 0.000
N20.0 Calculus of kidney
0.943 0.057 0.000
Z85 Personal history of malignant neoplasm
0.942 0.058 0.000
E70-E90 Metabolic disorders
0.941 0.059 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.940 0.060 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.939 0.061 0.000
D12 Benign neoplasm of colon, rectum, anus and anal canal
0.933 0.067 0.000
Z95.1 Presence of aortocoronary bypass graft
0.932 0.068 0.000
Z95.2 Presence of prosthetic heart valve
0.930 0.070 0.000
M15-M19 Arthrosis
0.929 0.071 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.929 0.071 0.000
Z85.8 Personal history of malignant neoplasms of other organs and systems
0.929 0.071 0.000
I24 Other acute ischaemic heart diseases
0.927 0.073 0.000
M19 Other arthrosis
0.926 0.074 0.000
Z95.5 Presence of coronary angioplasty implant and graft
0.926 0.074 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.925 0.075 0.000
K20 Oesophagitis
0.920 0.080 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.919 0.081 0.000
M05-M14 Inflammatory polyarthropathies
0.917 0.083 0.000
M19.9 Arthrosis, unspecified
0.913 0.087 0.000
K26 Duodenal ulcer
0.912 0.088 0.000
K55-K64 Other diseases of intestines
0.911 0.089 0.000
D23.1 Skin of eyelid, including canthus
0.904 0.096 0.000
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified
0.901 0.099 0.000
L82 Seborrhoeic keratosis
0.891 0.109 0.000
I35 Nonrheumatic aortic valve disorders
0.888 0.112 0.000
D18 Haemangioma and lymphangioma, any site
0.888 0.112 0.000
N20.1 Calculus of ureter
0.887 0.113 0.000
Z85.5 Personal history of malignant neoplasm of urinary tract
0.887 0.113 0.000
F30-F39 Mood [affective] disorders
0.887 0.113 0.000
C44.1 Skin of eyelid, including canthus
0.886 0.114 0.000
H53-H54 Visual disturbances and blindness
0.885 0.115 0.000
D12.4 Descending colon
0.885 0.115 0.000
F41 Other anxiety disorders
0.884 0.116 0.000
C44.4 Skin of scalp and neck
0.884 0.116 0.000
I20.0 Unstable angina
0.882 0.118 0.000
K07 Dentofacial anomalies [including malocclusion]
0.882 0.118 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.877 0.123 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.876 0.124 0.000
N18 Chronic renal failure
0.875 0.125 0.000
E78 Disorders of lipoprotein metabolism and other lipidaemias
0.873 0.127 0.000
K50-K52 Noninfective enteritis and colitis
0.872 0.128 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.871 0.129 0.000
N23 Unspecified renal colic
0.869 0.131 0.000
S61.8 Open wound of other parts of wrist and hand
0.869 0.131 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.868 0.132 0.000
L03 Cellulitis
0.867 0.133 0.000
F41.2 Mixed anxiety and depressive disorder
0.867 0.133 0.000
K61 Abscess of anal and rectal regions
0.866 0.134 0.000
H40.0 Glaucoma suspect
0.862 0.138 0.000
M19.99 Arthrosis, unspecified (Site unspecified)
0.861 0.139 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.861 0.139 0.000
N92 Excessive, frequent and irregular menstruation
0.858 0.142 0.000
N10-N16 Renal tubulo-interstitial diseases
0.855 0.145 0.000
W20-W49 Exposure to inanimate mechanical forces
0.853 0.147 0.000
N89 Other noninflammatory disorders of vagina
0.852 0.148 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.849 0.151 0.000
L92 Granulomatous disorders of skin and subcutaneous tissue
0.847 0.153 0.000
H40.9 Glaucoma, unspecified
0.847 0.153 0.000
H40.1 Primary open-angle glaucoma
0.847 0.153 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.843 0.157 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.842 0.158 0.000
I47 Paroxysmal tachycardia
0.842 0.158 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.841 0.159 0.000
W00-W19 Falls
0.841 0.159 0.000
Z93 Artificial opening status
0.840 0.160 0.000
M13 Other arthritis
0.837 0.163 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.836 0.164 0.000
I20.9 Angina pectoris, unspecified
0.835 0.165 0.000
K61.0 Anal abscess
0.834 0.166 0.000
M19.0 Primary arthrosis of other joints
0.833 0.167 0.000
C43 Malignant melanoma of skin
0.833 0.167 0.000
Y57 Other and unspecified drugs and medicaments
0.831 0.169 0.000
E78.5 Hyperlipidaemia, unspecified
0.830 0.170 0.000
D22 Melanocytic naevi
0.828 0.172 0.000
E21.3 Hyperparathyroidism, unspecified
0.828 0.172 0.000
L40-L45 Papulosquamous disorders
0.827 0.173 0.000
K05 Gingivitis and periodontal diseases
0.826 0.174 0.000
E21.0 Primary hyperparathyroidism
0.824 0.176 0.000
D23.7 Skin of lower limb, including hip
0.823 0.177 0.000
I44 Atrioventricular and left bundle-branch block
0.823 0.177 0.000
K04.8 Radicular cyst
0.823 0.177 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.821 0.179 0.000
D27 Benign neoplasm of ovary
0.820 0.180 0.000
K04.7 Periapical abscess without sinus
0.819 0.181 0.000
I24.8 Other forms of acute ischaemic heart disease
0.819 0.181 0.000
M19.90 Arthrosis, unspecified (Multiple sites)
0.818 0.182 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.816 0.184 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.813 0.187 0.000
D18.0 Haemangioma, any site
0.811 0.189 0.000
K14 Diseases of tongue
0.810 0.190 0.000
S90-S99 Injuries to the ankle and foot
0.809 0.191 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.807 0.193 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.806 0.194 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.805 0.195 0.000
S00-S09 Injuries to the head
0.802 0.198 0.000
L98.8 Other specified disorders of skin and subcutaneous tissue
0.801 0.199 0.000
L90 Atrophic disorders of skin
0.799 0.201 0.000
N80 Endometriosis
0.798 0.202 0.000
H53 Visual disturbances
0.797 0.203 0.000
Z94 Transplanted organ and tissue status
0.796 0.204 0.000
S20-S29 Injuries to the thorax
0.794 0.206 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.793 0.207 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.792 0.208 0.000
C64-C68 Malignant neoplasms of urinary tract
0.792 0.208 0.000
M70-M79 Other soft tissue disorders
0.791 0.209 0.000
S70-S79 Injuries to the hip and thigh
0.791 0.209 0.000
D32 Benign neoplasm of meninges
0.789 0.211 0.000
T66-T78 Other and unspecified effects of external causes
0.789 0.211 0.000
K56.5 Intestinal adhesions [bands] with obstruction
0.788 0.212 0.000
I35.2 Aortic (valve) stenosis with insufficiency
0.787 0.213 0.000
I60-I69 Cerebrovascular diseases
0.785 0.215 0.000
K07.3 Anomalies of tooth position
0.785 0.215 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.785 0.215 0.000
Z95.8 Presence of other cardiac and vascular implants and grafts
0.785 0.215 0.000
N00-N08 Glomerular diseases
0.783 0.217 0.000
L03.3 Cellulitis of trunk
0.782 0.217 0.000
C44.6 Skin of upper limb, including shoulder
0.782 0.218 0.000
S68 Traumatic amputation of wrist and hand
0.781 0.219 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.781 0.219 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.778 0.222 0.000
I44.0 Atrioventricular block, first degree
0.778 0.222 0.000
D23.6 Skin of upper limb, including shoulder
0.778 0.222 0.000
I36 Nonrheumatic tricuspid valve disorders
0.777 0.223 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.777 0.223 0.000
K22 Other diseases of oesophagus
0.777 0.223 0.000
D00-D09 In situ neoplasms
0.777 0.223 0.000
C44.0 Skin of lip
0.776 0.224 0.000
L89 Decubitus ulcer
0.776 0.224 0.000
X20-X29 Contact with venomous animals and plants
0.776 0.224 0.000
I42 Cardiomyopathy
0.776 0.224 0.000
I33 Acute and subacute endocarditis
0.772 0.228 0.000
K51 Ulcerative colitis
0.772 0.228 0.000
K11 Diseases of salivary glands
0.772 0.228 0.000
Z89 Acquired absence of limb
0.771 0.229 0.000
I51 Complications and ill-defined descriptions of heart disease
0.770 0.230 0.000
F31 Bipolar affective disorder
0.770 0.230 0.000
N89.8 Other specified noninflammatory disorders of vagina
0.770 0.230 0.000
D10 Benign neoplasm of mouth and pharynx
0.769 0.231 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.769 0.231 0.000
M11 Other crystal arthropathies
0.768 0.232 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.768 0.232 0.000
F44 Dissociative [conversion] disorders
0.767 0.233 0.000
N25-N29 Other disorders of kidney and ureter
0.767 0.233 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
E28 Ovarian dysfunction
0.766 0.234 0.000
K56.6 Other and unspecified intestinal obstruction
0.766 0.234 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.765 0.235 0.000
S61.1 Open wound of finger(s) with damage to nail
0.765 0.235 0.000
Chapter XXII Codes for special purposes
0.763 0.237 0.000
L08 Other local infections of skin and subcutaneous tissue
0.763 0.237 0.000
K26.5 Chronic or unspecified with perforation
0.763 0.237 0.000
N94.8 Other specified conditions associated with female genital organs and menstrual cycle
0.762 0.238 0.000
K58 Irritable bowel syndrome
0.762 0.238 0.000
I25.5 Ischaemic cardiomyopathy
0.760 0.240 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.760 0.240 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.760 0.240 0.000
L98.9 Disorder of skin and subcutaneous tissue, unspecified
0.760 0.240 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.759 0.241 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.759 0.241 0.000
E29 Testicular dysfunction
0.758 0.242 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.758 0.242 0.000
E50-E64 Other nutritional deficiencies
0.757 0.243 0.000
V10-V19 Pedal cyclist injured in transport accident
0.756 0.244 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.756 0.244 0.000
S67 Crushing injury of wrist and hand
0.755 0.245 0.000
N92.3 Ovulation bleeding
0.755 0.245 0.000
D12.7 Rectosigmoid junction
0.755 0.245 0.000
M19.96 Arthrosis, unspecified-Lower leg
0.754 0.246 0.000
Y57.9 Drug or medicament, unspecified
0.754 0.246 0.000
N20.2 Calculus of kidney with calculus of ureter
0.754 0.246 0.000
H55-H59 Other disorders of eye and adnexa
0.753 0.247 0.000
C44.7 Skin of lower limb, including hip
0.752 0.248 0.000
K04.6 Periapical abscess with sinus
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.751 0.249 0.000
M13.9 Arthritis, unspecified
0.749 0.251 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.749 0.251 0.000
F33 Recurrent depressive disorder
0.747 0.253 0.000
I22 Subsequent myocardial infarction
0.746 0.254 0.000
I30 Acute pericarditis
0.745 0.255 0.000
I05-I09 Chronic rheumatic heart diseases
0.745 0.255 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.742 0.258 0.000
M19.1 Posttraumatic arthrosis of other joints
0.742 0.258 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.742 0.258 0.000
M00-M03 Infectious arthropathies
0.741 0.259 0.000
V80-V89 Other land transport accidents
0.740 0.260 0.000
Z93.3 Colostomy status
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.740 0.260 0.000
K13 Other diseases of lip and oral mucosa
0.739 0.261 0.000
M45-M49 Spondylopathies
0.738 0.262 0.000
D23.4 Skin of scalp and neck
0.738 0.262 0.000
K04.9 Other and unspecified diseases of pulp and periapical tissues
0.737 0.263 0.000
I35.9 Aortic valve disorder, unspecified
0.737 0.263 0.000
E83 Disorders of mineral metabolism
0.737 0.263 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.736 0.264 0.000
M19.07 Primary arthrosis of other joints (Ankle and foot)
0.736 0.264 0.000
K06.8 Other specified disorders of gingiva and edentulous alveolar ridge
0.735 0.265 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.735 0.265 0.000
K22.1 Ulcer of oesophagus
0.735 0.265 0.000
L92.9 Granulomatous disorder of skin and subcutaneous tissue, unspecified
0.734 0.266 0.000
S50-S59 Injuries to the elbow and forearm
0.733 0.267 0.000
N95 Menopausal and other perimenopausal disorders
0.732 0.268 0.000
Y40 Systemic antibiotics
0.731 0.269 0.000
V20-V29 Motorcycle rider injured in transport accident
0.729 0.271 0.000
C43.7 Malignant melanoma of lower limb, including hip
0.729 0.271 0.000
C44.2 Skin of ear and external auricular canal
0.729 0.271 0.000
N18.2 Chronic kidney disease, stage 2
0.727 0.273 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.725 0.274 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.725 0.275 0.000
L81 Other disorders of pigmentation
0.725 0.275 0.000
N97 Female infertility
0.724 0.276 0.000
N99-N99 Other disorders of the genitourinary system
0.724 0.276 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.724 0.276 0.000
I35.0 Aortic (valve) stenosis
0.723 0.277 0.000
N80.1 Endometriosis of ovary
0.723 0.277 0.000
S64 Injury of nerves at wrist and hand level
0.722 0.278 0.000
H10-H13 Disorders of conjunctiva
0.722 0.278 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.721 0.279 0.000
D11 Benign neoplasm of major salivary glands
0.720 0.280 0.000
F80-F89 Disorders of psychological development
0.720 0.280 0.000
N86 Erosion and ectropion of cervix uteri
0.719 0.281 0.000
K12 Stomatitis and related lesions
0.718 0.281 0.000
E23 Hypofunction and other disorders of pituitary gland
0.718 0.282 0.000
D48.1 Connective and other soft tissue
0.718 0.282 0.000
N87 Dysplasia of cervix uteri
0.718 0.282 0.000
N18.9 Chronic renal failure, unspecified
0.717 0.283 0.000
L90.5 Scar conditions and fibrosis of skin
0.717 0.283 0.000
E05 Thyrotoxicosis [hyperthyroidism]
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
K02 Dental caries
0.717 0.283 0.000
Z92 Personal history of medical treatment
0.717 0.283 0.000
C44.9 Malignant neoplasm of skin, unspecified
0.717 0.283 0.000
C44.8 Overlapping lesion of skin
0.717 0.283 0.000
I00-I02 Acute rheumatic fever
0.716 0.283 0.000
E40-E46 Malnutrition
0.716 0.283 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.716 0.284 0.000
T33-T35 Frostbite
0.716 0.284 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.716 0.284 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.716 0.284 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.716 0.284 0.000
T00-T07 Injuries involving multiple body regions
0.716 0.284 0.000
S10-S19 Injuries to the neck
0.716 0.284 0.000
D41.4 Bladder
0.716 0.284 0.000
Z93.2 Ileostomy status
0.716 0.284 0.000
N94.6 Dysmenorrhoea, unspecified
0.716 0.284 0.000
L50-L54 Urticaria and erythema
0.715 0.285 0.000
I71 Aortic aneurysm and dissection
0.715 0.285 0.000
D22.7 Melanocytic naevi of lower limb, including hip
0.714 0.286 0.000
I23 Certain current complications following acute myocardial infarction
0.714 0.286 0.000
N71 Inflammatory disease of uterus, except cervix
0.714 0.286 0.000
D31 Benign neoplasm of eye and adnexa
0.714 0.286 0.000
D30 Benign neoplasm of urinary organs
0.714 0.286 0.000
D29 Benign neoplasm of male genital organs
0.714 0.286 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.714 0.286 0.000
D26 Other benign neoplasms of uterus
0.714 0.286 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.714 0.286 0.000
D19 Benign neoplasm of mesothelial tissue
0.714 0.286 0.000
D16 Benign neoplasm of bone and articular cartilage
0.714 0.286 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.714 0.286 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.714 0.286 0.000
M10 Gout
0.713 0.287 0.000
L10-L14 Bullous disorders
0.713 0.287 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.713 0.287 0.000
E06 Thyroiditis
0.713 0.287 0.000
E01 Iodine-deficiency-related thyroid disorders and allied conditions
0.713 0.287 0.000
E00 Congenital iodine-deficiency syndrome
0.713 0.287 0.000
E02 Subclinical iodine-deficiency hypothyroidism
0.713 0.287 0.000
W22 Striking against or struck by other objects
0.712 0.288 0.000
D13 Benign neoplasm of other and ill-defined parts of digestive system
0.712 0.288 0.000
L05 Pilonidal cyst
0.712 0.288 0.000
M19.09 Primary arthrosis of other joints (Site unspecified)
0.711 0.289 0.000
E03.8 Other specified hypothyroidism
0.711 0.289 0.000
E03.5 Myxoedema coma
0.711 0.289 0.000
E03.4 Atrophy of thyroid (acquired)
0.711 0.289 0.000
E03.3 Postinfectious hypothyroidism
0.711 0.289 0.000
E03.2 Hypothyroidism due to medicaments and other exogenous substances
0.711 0.289 0.000
E03.1 Congenital hypothyroidism without goitre
0.711 0.289 0.000
E03.0 Congenital hypothyroidism with diffuse goitre
0.711 0.289 0.000
Z95.3 Presence of xenogenic heart valve
0.711 0.289 0.000
K10 Other diseases of jaws
0.710 0.290 0.000
K09 Cysts of oral region, not elsewhere classified
0.710 0.290 0.000
K03 Other diseases of hard tissues of teeth
0.710 0.290 0.000
K00 Disorders of tooth development and eruption
0.710 0.290 0.000
S69 Other and unspecified injuries of wrist and hand
0.710 0.290 0.000
S65 Injury of blood vessels at wrist and hand level
0.710 0.290 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.710 0.290 0.000
S60 Superficial injury of wrist and hand
0.710 0.290 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.710 0.290 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.709 0.291 0.000
S80-S89 Injuries to the knee and lower leg
0.709 0.291 0.000
M86-M90 Other osteopathies
0.708 0.292 0.000
D12.8 Rectum
0.708 0.292 0.000
I47.2 Ventricular tachycardia
0.708 0.292 0.000
X60-X84 Intentional self-harm
0.706 0.293 0.000
L03.2 Cellulitis of face
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
Y35-Y36 Legal intervention and operations of war
0.705 0.295 0.000
Y10-Y34 Event of undetermined intent
0.705 0.295 0.000
Y00-Y09 Assault
0.705 0.295 0.000
X85-X99 Assault
0.705 0.295 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.705 0.295 0.000
X50-X57 Overexertion, travel and privation
0.705 0.295 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.705 0.295 0.000
X30-X39 Exposure to forces of nature
0.705 0.295 0.000
X10-X19 Contact with heat and hot substances
0.705 0.295 0.000
X00-X09 Exposure to smoke, fire and flames
0.705 0.295 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.705 0.295 0.000
W75-W84 Other accidental threats to breathing
0.705 0.295 0.000
W65-W74 Accidental drowning and submersion
0.705 0.295 0.000
W50-W64 Exposure to animate mechanical forces
0.705 0.295 0.000
V98-V99 Other and unspecified transport accidents
0.705 0.295 0.000
V95-V97 Air and space transport accidents
0.705 0.295 0.000
V90-V94 Water transport accidents
0.705 0.295 0.000
V70-V79 Bus occupant injured in transport accident
0.705 0.295 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.705 0.295 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.705 0.295 0.000
V40-V49 Car occupant injured in transport accident
0.705 0.295 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.705 0.295 0.000
V01-V09 Pedestrian injured in transport accident
0.705 0.295 0.000
Z85.7 Personal history of other malignant neoplasms of lymphoid, haematopoietic and related tissues
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
C92 Myeloid leukaemia
0.703 0.296 0.000
D22.3 Melanocytic naevi of other and unspecified parts of face
0.703 0.297 0.000
I38 Endocarditis, valve unspecified
0.703 0.297 0.000
M19.98 Arthrosis, unspecified (Other)
0.703 0.297 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.703 0.297 0.000
D12.2 Ascending colon
0.702 0.298 0.000
W10 Fall on and from stairs and steps
0.702 0.298 0.000
D23.5 Skin of trunk
0.702 0.298 0.000
L99 Other disorders of skin and subcutaneous tissue in diseases classified elsewhere
0.702 0.298 0.000
L95 Vasculitis limited to skin, not elsewhere classified
0.702 0.298 0.000
L94 Other localised connective tissue disorders
0.702 0.298 0.000
L93 Lupus erythematosus
0.702 0.298 0.000
L87 Transepidermal elimination disorders
0.702 0.298 0.000
L88 Pyoderma gangrenosum
0.702 0.298 0.000
L86 Keratoderma in diseases classified elsewhere
0.702 0.298 0.000
L83 Acanthosis nigricans
0.702 0.298 0.000
L80 Vitiligo
0.702 0.298 0.000
S61.7 Multiple open wounds of wrist and hand
0.701 0.298 0.000
E87.6 Hypokalaemia
0.702 0.298 0.000
N20.9 Urinary calculus, unspecified
0.701 0.299 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.700 0.300 0.000
F70-F79 Mental retardation
0.700 0.300 0.000
F60-F69 Disorders of adult personality and behaviour
0.700 0.300 0.000
L85 Other epidermal thickening
0.699 0.301 0.000
E87.2 Acidosis
0.699 0.301 0.000
N85 Other noninflammatory disorders of uterus, except cervix
0.698 0.302 0.000
M91-M94 Chondropathies
0.698 0.302 0.000
M60-M63 Disorders of muscles
0.698 0.302 0.000
C85.1 B-cell lymphoma, unspecified
0.698 0.302 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.697 0.303 0.000
H18 Other disorders of cornea
0.697 0.303 0.000
D35.1 Parathyroid gland
0.697 0.303 0.000
I52 Other heart disorders in diseases classified elsewhere
0.696 0.304 0.000
I48 Atrial fibrillation and flutter
0.696 0.304 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.696 0.304 0.000
I41 Myocarditis in diseases classified elsewhere
0.696 0.304 0.000
I40 Acute myocarditis
0.696 0.304 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.696 0.304 0.000
I37 Pulmonary valve disorders
0.696 0.304 0.000
I32 Pericarditis in diseases classified elsewhere
0.696 0.304 0.000
L43 Lichen planus
0.696 0.304 0.000
H43-H45 Disorders of vitreous body and globe
0.695 0.305 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.694 0.306 0.000
Y52 Agents primarily affecting the cardiovascular system
0.694 0.306 0.000
Z84 Family history of other conditions
0.694 0.306 0.000
Z81 Family history of mental and behavioural disorders
0.694 0.306 0.000
Z85.6 Personal history of leukaemia
0.694 0.306 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.693 0.307 0.000
D23.9 Skin, unspecified
0.693 0.307 0.000
D23.2 Skin of ear and external auricular canal
0.693 0.307 0.000
D23.0 Skin of lip
0.693 0.307 0.000
N98 Complications associated with artificial fertilisation
0.693 0.307 0.000
N91 Absent, scanty and rare menstruation
0.693 0.307 0.000
N82 Fistulae involving female genital tract
0.693 0.307 0.000
N96 Habitual aborter
0.693 0.307 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.693 0.307 0.000
E34 Other endocrine disorders
0.693 0.307 0.000
E32 Diseases of thymus
0.693 0.307 0.000
E31 Polyglandular dysfunction
0.693 0.307 0.000
E30 Disorders of puberty, not elsewhere classified
0.693 0.307 0.000
E27 Other disorders of adrenal gland
0.693 0.307 0.000
E26 Hyperaldosteronism
0.693 0.307 0.000
E25 Adrenogenital disorders
0.693 0.307 0.000
E24 Cushing's syndrome
0.693 0.307 0.000
E22 Hyperfunction of pituitary gland
0.693 0.307 0.000
E20 Hypoparathyroidism
0.693 0.307 0.000
I45 Other conduction disorders
0.692 0.308 0.000
C44.5 Skin of trunk
0.691 0.309 0.000
S40-S49 Injuries to the shoulder and upper arm
0.691 0.309 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.690 0.310 0.000
D12.6 Colon, unspecified
0.690 0.310 0.000
I46 Cardiac arrest
0.689 0.311 0.000
I25.6 Silent myocardial ischaemia
0.689 0.311 0.000
I25.4 Coronary artery aneurysm
0.689 0.311 0.000
I25.3 Aneurysm of heart
0.689 0.311 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.689 0.311 0.000
H53.8 Other visual disturbances
0.689 0.311 0.000
H54 Blindness and low vision
0.689 0.311 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.688 0.311 0.000
H42 Glaucoma in diseases classified elsewhere
0.688 0.312 0.000
Y44 Agents primarily affecting blood constituents
0.688 0.312 0.000
K05.1 Chronic gingivitis
0.687 0.313 0.000
H25-H28 Disorders of lens
0.686 0.314 0.000
M65-M68 Disorders of synovium and tendon
0.686 0.314 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.686 0.314 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.685 0.314 0.000
D46 Myelodysplastic syndromes
0.685 0.315 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.685 0.315 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.685 0.315 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.685 0.315 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.685 0.315 0.000
C67 Malignant neoplasm of bladder
0.685 0.315 0.000
I47.9 Paroxysmal tachycardia, unspecified
0.684 0.316 0.000
M13.0 Polyarthritis, unspecified
0.683 0.317 0.000
M80-M85 Disorders of bone density and structure
0.683 0.317 0.000
N18.3 Chronic kidney disease, stage 3
0.683 0.317 0.000
K07.6 Temporomandibular joint disorders
0.681 0.319 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.681 0.319 0.000
K28 Gastrojejunal ulcer
0.680 0.320 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.680 0.320 0.000
L02 Cutaneous abscess, furuncle and carbuncle
0.680 0.320 0.000
S01 Open wound of head
0.679 0.321 0.000
K25 Gastric ulcer
0.679 0.321 0.000
M19.97 Arthrosis, unspecified (Ankle and foot)
0.678 0.322 0.000
N92.4 Excessive bleeding in the premenopausal period
0.678 0.322 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.677 0.323 0.000
K04.3 Abnormal hard tissue formation in pulp
0.677 0.323 0.000
K04.2 Pulp degeneration
0.677 0.323 0.000
K04.1 Necrosis of pulp
0.677 0.323 0.000
K04.0 Pulpitis
0.677 0.323 0.000
N72 Inflammatory disease of cervix uteri
0.677 0.323 0.000
Z88.0 Personal history of allergy to penicillin
0.677 0.323 0.000
H40.8 Other glaucoma
0.677 0.323 0.000
H40.6 Glaucoma secondary to drugs
0.677 0.323 0.000
H40.5 Glaucoma secondary to other eye disorders
0.677 0.323 0.000
H40.4 Glaucoma secondary to eye inflammation
0.677 0.323 0.000
H40.3 Glaucoma secondary to eye trauma
0.677 0.323 0.000
S62 Fracture at wrist and hand level
0.677 0.323 0.000
I20.1 Angina pectoris with documented spasm
0.676 0.324 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.676 0.324 0.000
Z85.0 Personal history of malignant neoplasm of digestive organs
0.675 0.325 0.000
Z85.9 Personal history of malignant neoplasm, unspecified
0.675 0.325 0.000
Z85.2 Personal history of malignant neoplasm of other respiratory and intrathoracic organs
0.675 0.325 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.675 0.325 0.000
M05 Seropositive rheumatoid arthritis
0.675 0.325 0.000
E88 Other metabolic disorders
0.675 0.325 0.000
E85 Amyloidosis
0.675 0.325 0.000
E84 Cystic fibrosis
0.675 0.325 0.000
E79 Disorders of purine and pyrimidine metabolism
0.675 0.325 0.000
E77 Disorders of glycoprotein metabolism
0.675 0.325 0.000
E76 Disorders of glycosaminoglycan metabolism
0.675 0.325 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.675 0.325 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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