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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16877816
log Bayes Factor = 15.7775
Chromosome 5   position 59,568,716  (GRCh37) Explore rs16877816 on Ensembl!
Variant rs16877816 is part of Cluster X0224

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
E10-E14 Diabetes mellitus
0.999 0.001 0.000
M50-M54 Other dorsopathies
0.993 0.007 0.000
Chapter XI Diseases of the digestive system
0.993 0.007 0.000
K70-K77 Diseases of liver
0.990 0.010 0.000
N17-N19 Renal failure
0.989 0.011 0.000
M20-M25 Other joint disorders
0.986 0.014 0.000
Chapter X Diseases of the respiratory system
0.985 0.015 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.984 0.016 0.000
M54 Dorsalgia
0.983 0.017 0.000
E11 Non-insulin-dependent diabetes mellitus
0.983 0.017 0.000
Chapter VII Diseases of the eye and adnexa
0.982 0.018 0.000
E10 Insulin-dependent diabetes mellitus
0.981 0.019 0.000
Chapter VIII Diseases of the ear and mastoid process
0.980 0.020 0.000
N83 Noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.974 0.026 0.000
N18 Chronic renal failure
0.970 0.030 0.000
E20-E35 Disorders of other endocrine glands
0.968 0.032 0.000
J40-J47 Chronic lower respiratory diseases
0.964 0.036 0.000
E11.9 Without complications
0.962 0.038 0.000
S00-S09 Injuries to the head
0.953 0.047 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.953 0.047 0.000
M20 Acquired deformities of fingers and toes
0.952 0.048 0.000
K70 Alcoholic liver disease
0.952 0.048 0.000
E10.9 Without complications
0.946 0.054 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.941 0.059 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.931 0.069 0.000
Chapter V Mental and behavioural disorders
0.926 0.074 0.000
N20-N23 Urolithiasis
0.926 0.074 0.000
N25-N29 Other disorders of kidney and ureter
0.923 0.077 0.000
K75 Other inflammatory liver diseases
0.921 0.079 0.000
S60-S69 Injuries to the wrist and hand
0.921 0.079 0.000
M80-M85 Disorders of bone density and structure
0.918 0.082 0.000
H65-H75 Diseases of middle ear and mastoid
0.918 0.082 0.000
H90-H95 Other disorders of ear
0.917 0.083 0.000
N83.2 Other and unspecified ovarian cysts
0.914 0.086 0.000
N10-N16 Renal tubulo-interstitial diseases
0.914 0.086 0.000
N80 Endometriosis
0.913 0.087 0.000
J43 Emphysema
0.912 0.088 0.000
J45 Asthma
0.910 0.090 0.000
M54.9 Dorsalgia, unspecified
0.910 0.090 0.000
K76 Other diseases of liver
0.908 0.092 0.000
N87 Dysplasia of cervix uteri
0.907 0.093 0.000
N18.9 Chronic renal failure, unspecified
0.905 0.095 0.000
M54.3 Sciatica
0.903 0.097 0.000
M54.5 Low back pain
0.901 0.099 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.901 0.099 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.898 0.101 0.000
M51 Other intervertebral disk disorders
0.898 0.102 0.000
H53-H54 Visual disturbances and blindness
0.897 0.103 0.000
E21 Hyperparathyroidism and other disorders of parathyroid gland
0.897 0.103 0.000
Chapter VI Diseases of the nervous system
0.893 0.107 0.000
K35-K38 Diseases of appendix
0.893 0.107 0.000
N83.1 Corpus luteum cyst
0.891 0.109 0.000
M22 Disorders of patella
0.890 0.110 0.000
N00-N08 Glomerular diseases
0.889 0.111 0.000
H25-H28 Disorders of lens
0.888 0.112 0.000
J45.9 Asthma, unspecified
0.886 0.114 0.000
M20.5 Other deformities of toe(s) (acquired)
0.881 0.119 0.000
K70.3 Alcoholic cirrhosis of liver
0.878 0.122 0.000
E65-E68 Obesity and other hyperalimentation
0.876 0.124 0.000
J43.9 Emphysema, unspecified
0.874 0.126 0.000
M70-M79 Other soft tissue disorders
0.869 0.131 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.868 0.132 0.000
M05-M14 Inflammatory polyarthropathies
0.866 0.134 0.000
S00 Superficial injury of head
0.859 0.141 0.000
N19 Unspecified renal failure
0.855 0.145 0.000
M20.1 Hallux valgus (acquired)
0.854 0.146 0.000
M54.39 Sciatica (Site unspecified)
0.851 0.149 0.000
M51.2 Other specified intervertebral disk displacement
0.850 0.150 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.845 0.155 0.000
M24 Other specific joint derangements
0.845 0.155 0.000
N84 Polyp of female genital tract
0.841 0.158 0.000
Chapter XXII Codes for special purposes
0.833 0.167 0.000
J00-J06 Acute upper respiratory infections
0.833 0.167 0.000
N90 Other noninflammatory disorders of vulva and perineum
0.832 0.168 0.000
N13 Obstructive and reflux uropathy
0.831 0.169 0.000
N60-N64 Disorders of breast
0.831 0.169 0.000
N83.8 Other noninflammatory disorders of ovary, Fallopian tube and broad ligament
0.830 0.170 0.000
N30-N39 Other diseases of urinary system
0.830 0.170 0.000
S90-S99 Injuries to the ankle and foot
0.827 0.173 0.000
M45-M49 Spondylopathies
0.826 0.174 0.000
K04 Diseases of pulp and periapical tissues
0.822 0.178 0.000
M54.56 Low back pain (Lumbar region)
0.821 0.178 0.000
N18.5 Chronic kidney disease, stage 5
0.821 0.179 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.821 0.179 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.821 0.179 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.820 0.180 0.000
E21.3 Hyperparathyroidism, unspecified
0.818 0.182 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.817 0.183 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.817 0.183 0.000
K82 Other diseases of gallbladder
0.816 0.184 0.000
K37 Unspecified appendicitis
0.815 0.185 0.000
K75.4 Autoimmune hepatitis
0.815 0.185 0.000
K70.9 Alcoholic liver disease, unspecified
0.813 0.187 0.000
M22.4 Chondromalacia patellae
0.813 0.187 0.000
E27 Other disorders of adrenal gland
0.812 0.188 0.000
E10.2 With renal complications
0.812 0.188 0.000
N92 Excessive, frequent and irregular menstruation
0.812 0.188 0.000
H90 Conductive and sensorineural hearing loss
0.811 0.189 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.810 0.190 0.000
M54.57 Low back pain (Lumbosacral region)
0.809 0.191 0.000
K05 Gingivitis and periodontal diseases
0.809 0.191 0.000
N21 Calculus of lower urinary tract
0.808 0.192 0.000
M20.2 Hallux rigidus
0.808 0.192 0.000
H54 Blindness and low vision
0.808 0.192 0.000
T79-T79 Certain early complications of trauma
0.807 0.193 0.000
K76.0 Fatty (change of) liver, not elsewhere classified
0.807 0.193 0.000
K86 Other diseases of pancreas
0.806 0.194 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.803 0.197 0.000
K83 Other diseases of biliary tract
0.803 0.197 0.000
H26 Other cataract
0.801 0.199 0.000
N84.0 Polyp of corpus uteri
0.801 0.199 0.000
K80 Cholelithiasis
0.797 0.203 0.000
H55-H59 Other disorders of eye and adnexa
0.796 0.204 0.000
N87.0 Mild cervical dysplasia
0.794 0.206 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.793 0.207 0.000
M21 Other acquired deformities of limbs
0.792 0.208 0.000
N31 Neuromuscular dysfunction of bladder, not elsewhere classified
0.792 0.208 0.000
E11.4 With neurological complications
0.792 0.208 0.000
H60-H62 Diseases of external ear
0.791 0.209 0.000
N23 Unspecified renal colic
0.789 0.211 0.000
J84 Other interstitial pulmonary diseases
0.787 0.213 0.000
N80.0 Endometriosis of uterus
0.787 0.213 0.000
E66 Obesity
0.787 0.213 0.000
H73 Other disorders of tympanic membrane
0.786 0.214 0.000
J47 Bronchiectasis
0.784 0.216 0.000
H10-H13 Disorders of conjunctiva
0.783 0.217 0.000
H69 Other disorders of Eustachian tube
0.783 0.217 0.000
M81 Osteoporosis without pathological fracture
0.783 0.217 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.783 0.217 0.000
N80.3 Endometriosis of pelvic peritoneum
0.782 0.218 0.000
M91-M94 Chondropathies
0.782 0.218 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.782 0.218 0.000
N18.4 Chronic kidney disease, stage 4
0.778 0.222 0.000
M40-M43 Deforming dorsopathies
0.775 0.225 0.000
G90-G99 Other disorders of the nervous system
0.774 0.226 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.774 0.226 0.000
S80-S89 Injuries to the knee and lower leg
0.773 0.227 0.000
N18.3 Chronic kidney disease, stage 3
0.773 0.227 0.000
E10.1 With ketoacidosis
0.769 0.231 0.000
S10-S19 Injuries to the neck
0.768 0.232 0.000
E11.3 With ophthalmic complications
0.768 0.232 0.000
E26 Hyperaldosteronism
0.768 0.232 0.000
N31.8 Other neuromuscular dysfunction of bladder
0.766 0.234 0.000
K74 Fibrosis and cirrhosis of liver
0.765 0.235 0.000
K75.9 Inflammatory liver disease, unspecified
0.764 0.236 0.000
Chapter I Certain infectious and parasitic diseases
0.763 0.237 0.000
N83.0 Follicular cyst of ovary
0.761 0.239 0.000
K70.4 Alcoholic hepatic failure
0.761 0.239 0.000
S00.8 Superficial injury of other parts of head
0.761 0.239 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.761 0.239 0.000
H91 Other hearing loss
0.760 0.240 0.000
S70-S79 Injuries to the hip and thigh
0.760 0.240 0.000
M79.6 Pain in limb
0.760 0.240 0.000
S06 Intracranial injury
0.760 0.240 0.000
K76.8 Other specified diseases of liver
0.760 0.240 0.000
M25 Other joint disorders, not elsewhere classified
0.760 0.240 0.000
H92 Otalgia and effusion of ear
0.759 0.241 0.000
E10.3 With ophthalmic complications
0.758 0.242 0.000
E24 Cushing's syndrome
0.758 0.242 0.000
M05 Seropositive rheumatoid arthritis
0.757 0.243 0.000
T66-T78 Other and unspecified effects of external causes
0.756 0.244 0.000
S05 Injury of eye and orbit
0.756 0.244 0.000
N18.2 Chronic kidney disease, stage 2
0.756 0.244 0.000
T92 Sequelae of injuries of upper limb
0.756 0.244 0.000
N08 Glomerular disorders in diseases classified elsewhere
0.755 0.245 0.000
K02 Dental caries
0.755 0.245 0.000
M54.6 Pain in thoracic spine
0.754 0.246 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.752 0.248 0.000
E66.9 Obesity, unspecified
0.752 0.248 0.000
J81 Pulmonary oedema
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.250 0.000
E13 Other specified diabetes mellitus
0.749 0.251 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.749 0.251 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.748 0.252 0.000
N87.1 Moderate cervical dysplasia
0.748 0.252 0.000
S00.0 Superficial injury of scalp
0.747 0.253 0.000
M10 Gout
0.746 0.253 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.746 0.254 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.746 0.254 0.000
M80 Osteoporosis with pathological fracture
0.745 0.255 0.000
K08 Other disorders of teeth and supporting structures
0.745 0.255 0.000
S09 Other and unspecified injuries of head
0.744 0.256 0.000
M24.1 Other articular cartilage disorders
0.744 0.256 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.744 0.256 0.000
E14 Unspecified diabetes mellitus
0.743 0.257 0.000
Chapter XX External causes of morbidity and mortality
0.741 0.259 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.740 0.260 0.000
N17 Acute renal failure
0.739 0.261 0.000
H26.8 Other specified cataract
0.738 0.262 0.000
N26 Unspecified contracted kidney
0.735 0.265 0.000
M65-M68 Disorders of synovium and tendon
0.734 0.266 0.000
J30-J39 Other diseases of upper respiratory tract
0.732 0.268 0.000
N94 Pain and other conditions associated with female genital organs and menstrual cycle
0.731 0.269 0.000
E21.0 Primary hyperparathyroidism
0.731 0.269 0.000
K04.4 Acute apical periodontitis of pulpal origin
0.731 0.269 0.000
S01 Open wound of head
0.731 0.269 0.000
S61 Open wound of wrist and hand
0.730 0.270 0.000
E40-E46 Malnutrition
0.730 0.270 0.000
N80.1 Endometriosis of ovary
0.727 0.273 0.000
H71 Cholesteatoma of middle ear
0.726 0.274 0.000
S69 Other and unspecified injuries of wrist and hand
0.725 0.275 0.000
H53 Visual disturbances
0.725 0.275 0.000
K80.5 Calculus of bile duct without cholangitis or cholecystitis
0.724 0.276 0.000
N21.0 Calculus in bladder
0.724 0.276 0.000
E00-E07 Disorders of thyroid gland
0.723 0.277 0.000
E70-E90 Metabolic disorders
0.722 0.278 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.722 0.278 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.722 0.278 0.000
S63 Dislocation, sprain and strain of joints and ligaments at wrist and hand level
0.721 0.279 0.000
M86-M90 Other osteopathies
0.720 0.280 0.000
K75.8 Other specified inflammatory liver diseases
0.719 0.281 0.000
S20-S29 Injuries to the thorax
0.719 0.281 0.000
N28.8 Other specified disorders of kidney and ureter
0.718 0.282 0.000
J46 Status asthmaticus
0.717 0.282 0.000
K09 Cysts of oral region, not elsewhere classified
0.717 0.283 0.000
N90.7 Vulvar cyst
0.717 0.283 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
M60-M63 Disorders of muscles
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
K11 Diseases of salivary glands
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.717 0.283 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
H65 Nonsuppurative otitis media
0.717 0.283 0.000
E12 Malnutrition-related diabetes mellitus
0.716 0.284 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.714 0.286 0.000
K12 Stomatitis and related lesions
0.714 0.286 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.714 0.286 0.000
N92.4 Excessive bleeding in the premenopausal period
0.713 0.287 0.000
S50-S59 Injuries to the elbow and forearm
0.712 0.288 0.000
N13.3 Other and unspecified hydronephrosis
0.712 0.288 0.000
N10 Acute tubulo-interstitial nephritis
0.712 0.288 0.000
M53 Other dorsopathies, not elsewhere classified
0.712 0.288 0.000
N63 Unspecified lump in breast
0.710 0.290 0.000
N13.8 Other obstructive and reflux uropathy
0.710 0.290 0.000
K77 Liver disorders in diseases classified elsewhere
0.709 0.290 0.000
K73 Chronic hepatitis, not elsewhere classified
0.709 0.290 0.000
K72 Hepatic failure, not elsewhere classified
0.709 0.290 0.000
K71 Toxic liver disease
0.709 0.290 0.000
M82 Osteoporosis in diseases classified elsewhere
0.709 0.291 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.709 0.291 0.000
E10.4 With neurological complications
0.708 0.292 0.000
M84 Disorders of continuity of bone
0.708 0.292 0.000
M36 Systemic disorders of connective tissue in diseases classified elsewhere
0.707 0.293 0.000
M34 Systemic sclerosis
0.707 0.293 0.000
M33 Dermatopolymyositis
0.707 0.293 0.000
M32 Systemic lupus erythematosus
0.707 0.293 0.000
M30 Polyarteritis nodosa and related conditions
0.707 0.293 0.000
N18.0 End-stage renal disease
0.707 0.293 0.000
N98 Complications associated with artificial fertilisation
0.706 0.294 0.000
N91 Absent, scanty and rare menstruation
0.706 0.294 0.000
N82 Fistulae involving female genital tract
0.706 0.294 0.000
N96 Habitual aborter
0.706 0.294 0.000
K85 Acute pancreatitis
0.705 0.295 0.000
N28.9 Disorder of kidney and ureter, unspecified
0.705 0.295 0.000
S40-S49 Injuries to the shoulder and upper arm
0.705 0.295 0.000
M54.8 Other dorsalgia
0.705 0.295 0.000
M54.0 Panniculitis affecting regions of neck and back
0.705 0.295 0.000
E11.8 With unspecified complications
0.705 0.295 0.000
E11.7 With multiple complications
0.705 0.295 0.000
E11.6 With other specified complications
0.705 0.295 0.000
E11.1 With ketoacidosis
0.705 0.295 0.000
E11.0 With coma
0.705 0.295 0.000
N32 Other disorders of bladder
0.704 0.296 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.704 0.296 0.000
N04 Nephrotic syndrome
0.704 0.296 0.000
T86 Failure and rejection of transplanted organs and tissues
0.704 0.296 0.000
S64 Injury of nerves at wrist and hand level
0.704 0.296 0.000
E10.8 With unspecified complications
0.703 0.297 0.000
E10.7 With multiple complications
0.703 0.297 0.000
E10.6 With other specified complications
0.703 0.297 0.000
E10.5 With peripheral circulatory complications
0.703 0.297 0.000
E10.0 With coma
0.703 0.297 0.000
M54.2 Cervicalgia
0.702 0.298 0.000
H43-H45 Disorders of vitreous body and globe
0.702 0.298 0.000
K10 Other diseases of jaws
0.702 0.298 0.000
E11.2 With renal complications
0.701 0.299 0.000
E27.4 Other and unspecified adrenocortical insufficiency
0.701 0.299 0.000
E28 Ovarian dysfunction
0.701 0.299 0.000
N87.9 Dysplasia of cervix uteri, unspecified
0.701 0.299 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.700 0.300 0.000
E50-E64 Other nutritional deficiencies
0.700 0.300 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.700 0.300 0.000
N97 Female infertility
0.699 0.300 0.000
N20 Calculus of kidney and ureter
0.699 0.301 0.000
J01 Acute sinusitis
0.699 0.301 0.000
N83.9 Noninflammatory disorder of ovary, Fallopian tube and broad ligament, unspecified
0.698 0.302 0.000
N83.7 Haematoma of broad ligament
0.698 0.302 0.000
N83.6 Haematosalpinx
0.698 0.302 0.000
N83.5 Torsion of ovary, ovarian pedicle and Fallopian tube
0.698 0.302 0.000
N83.4 Prolapse and hernia of ovary and Fallopian tube
0.698 0.302 0.000
N83.3 Acquired atrophy of ovary and Fallopian tube
0.698 0.302 0.000
H90.5 Sensorineural hearing loss, unspecified
0.696 0.304 0.000
N18.8 Other chronic renal failure
0.696 0.304 0.000
N18.1 Chronic kidney disease, stage 1
0.696 0.304 0.000
M22.8 Other disorders of patella
0.695 0.305 0.000
E35 Disorders of endocrine glands in diseases classified elsewhere
0.694 0.306 0.000
E34 Other endocrine disorders
0.694 0.306 0.000
E32 Diseases of thymus
0.694 0.306 0.000
E31 Polyglandular dysfunction
0.694 0.306 0.000
E30 Disorders of puberty, not elsewhere classified
0.694 0.306 0.000
E29 Testicular dysfunction
0.694 0.306 0.000
E25 Adrenogenital disorders
0.694 0.306 0.000
E22 Hyperfunction of pituitary gland
0.694 0.306 0.000
E20 Hypoparathyroidism
0.694 0.306 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.694 0.306 0.000
K01 Embedded and impacted teeth
0.694 0.306 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.694 0.306 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.694 0.306 0.000
E11.5 With peripheral circulatory complications
0.693 0.307 0.000
H25 Senile cataract
0.693 0.307 0.000
N05 Unspecified nephritic syndrome
0.692 0.308 0.000
H73.8 Other specified disorders of tympanic membrane
0.691 0.308 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.691 0.309 0.000
J41 Simple and mucopurulent chronic bronchitis
0.691 0.309 0.000
H74 Other disorders of middle ear and mastoid
0.689 0.311 0.000
F00 Dementia in Alzheimer's disease
0.689 0.311 0.000
J42 Unspecified chronic bronchitis
0.689 0.311 0.000
E23 Hypofunction and other disorders of pituitary gland
0.688 0.312 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.687 0.313 0.000
H69.9 Eustachian tube disorder, unspecified
0.687 0.313 0.000
K86.8 Other specified diseases of pancreas
0.686 0.314 0.000
K05.6 Periodontal disease, unspecified
0.686 0.314 0.000
M81.9 Osteoporosis, unspecified
0.686 0.314 0.000
N80.8 Other endometriosis
0.685 0.315 0.000
J03 Acute tonsillitis
0.684 0.316 0.000
M20.6 Acquired deformity of toe(s), unspecified
0.684 0.316 0.000
S08 Traumatic amputation of part of head
0.683 0.317 0.000
S07 Crushing injury of head
0.683 0.317 0.000
S04 Injury of cranial nerves
0.683 0.317 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.683 0.317 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.683 0.317 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.683 0.317 0.000
K70.2 Alcoholic fibrosis and sclerosis of liver
0.683 0.317 0.000
K70.1 Alcoholic hepatitis
0.683 0.317 0.000
K70.0 Alcoholic fatty liver
0.683 0.317 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.680 0.319 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.679 0.321 0.000
J90-J94 Other diseases of pleura
0.679 0.321 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.678 0.322 0.000
M47 Spondylosis
0.677 0.323 0.000
G93 Other disorders of brain
0.676 0.324 0.000
G61 Inflammatory polyneuropathy
0.675 0.325 0.000
F17.1 Harmful use
0.675 0.325 0.000
K03 Other diseases of hard tissues of teeth
0.674 0.326 0.000
K00 Disorders of tooth development and eruption
0.674 0.326 0.000
S60 Superficial injury of wrist and hand
0.674 0.326 0.000
S81 Open wound of lower leg
0.672 0.327 0.000
M24.16 Other articular cartilage disorders (Lower leg)
0.672 0.328 0.000
K76.6 Portal hypertension
0.671 0.329 0.000
T79 Certain early complications of trauma, not elsewhere classified
0.669 0.330 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.669 0.331 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.668 0.332 0.000
H26.4 After-cataract
0.668 0.332 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.668 0.332 0.000
N28.1 Cyst of kidney, acquired
0.668 0.332 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.667 0.333 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.667 0.333 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.667 0.333 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.667 0.333 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.667 0.333 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.667 0.333 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.667 0.333 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.667 0.333 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.667 0.333 0.000
T36 Poisoning by systemic antibiotics
0.667 0.333 0.000
M79.62 Pain in limb (Upper arm)
0.667 0.333 0.000
S02 Fracture of skull and facial bones
0.667 0.333 0.000
F01 Vascular dementia
0.667 0.333 0.000
S67 Crushing injury of wrist and hand
0.666 0.334 0.000
H53.0 Amblyopia ex anopsia
0.666 0.334 0.000
N12 Tubulo-interstitial nephritis, not specified as acute or chronic
0.666 0.334 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.665 0.334 0.000
H54.4 Blindness, one eye
0.664 0.336 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.664 0.336 0.000
F80-F89 Disorders of psychological development
0.664 0.336 0.000
F70-F79 Mental retardation
0.664 0.336 0.000
F60-F69 Disorders of adult personality and behaviour
0.664 0.336 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.664 0.336 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.664 0.336 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.663 0.337 0.000
M54.4 Lumbago with sciatica
0.662 0.338 0.000
K07 Dentofacial anomalies [including malocclusion]
0.662 0.338 0.000
T93 Sequelae of injuries of lower limb
0.662 0.338 0.000
N60 Benign mammary dysplasia
0.662 0.338 0.000
F99-F99 Unspecified mental disorder
0.662 0.338 0.000
T39.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.662 0.338 0.000
N29 Other disorders of kidney and ureter in diseases classified elsewhere
0.661 0.338 0.000
N27 Small kidney of unknown cause
0.661 0.338 0.000
N25 Disorders resulting from impaired renal tubular function
0.661 0.338 0.000
T40.2 Other opioids
0.661 0.339 0.000
H04 Disorders of lachrymal system
0.661 0.339 0.000
K83.1 Obstruction of bile duct
0.661 0.339 0.000
M10.9 Gout, unspecified
0.661 0.339 0.000
K35 Acute appendicitis
0.661 0.339 0.000
S68 Traumatic amputation of wrist and hand
0.660 0.340 0.000
S65 Injury of blood vessels at wrist and hand level
0.660 0.340 0.000
K75.3 Granulomatous hepatitis, not elsewhere classified
0.660 0.340 0.000
K75.2 Nonspecific reactive hepatitis
0.660 0.340 0.000
K75.1 Phlebitis of portal vein
0.660 0.340 0.000
K75.0 Abscess of liver
0.660 0.340 0.000
M71 Other bursopathies
0.660 0.340 0.000
N08.3 Glomerular disorders in diabetes mellitus
0.659 0.341 0.000
M85 Other disorders of bone density and structure
0.658 0.342 0.000
M83 Adult osteomalacia
0.658 0.342 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.658 0.342 0.000
H70 Mastoiditis and related conditions
0.658 0.342 0.000
H68 Eustachian salpingitis and obstruction
0.658 0.342 0.000
H67 Otitis media in diseases classified elsewhere
0.658 0.342 0.000
H90.0 Conductive hearing loss, bilateral
0.658 0.342 0.000
H60 Otitis externa
0.658 0.342 0.000
H95 Postprocedural disorders of ear and mastoid process, not elsewhere classified
0.658 0.342 0.000
H94 Other disorders of ear in diseases classified elsewhere
0.658 0.342 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.657 0.342 0.000
S62 Fracture at wrist and hand level
0.657 0.343 0.000
N64 Other disorders of breast
0.656 0.344 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.656 0.344 0.000
J80 Adult respiratory distress syndrome
0.655 0.344 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.655 0.345 0.000
N15 Other renal tubulo-interstitial diseases
0.655 0.345 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.655 0.345 0.000
N11 Chronic tubulo-interstitial nephritis
0.655 0.345 0.000
S90 Superficial injury of ankle and foot
0.655 0.345 0.000
M46 Other inflammatory spondylopathies
0.655 0.345 0.000
N80.6 Endometriosis in cutaneous scar
0.654 0.346 0.000
N80.5 Endometriosis of intestine
0.654 0.346 0.000
N80.4 Endometriosis of rectovaginal septum and vagina
0.654 0.346 0.000
N80.2 Endometriosis of Fallopian tube
0.654 0.346 0.000
D80-D89 Certain disorders involving the immune mechanism
0.654 0.346 0.000
J43.8 Other emphysema
0.654 0.346 0.000
J43.2 Centrilobular emphysema
0.654 0.346 0.000
J43.1 Panlobular emphysema
0.654 0.346 0.000
J43.0 MacLeod's syndrome
0.654 0.346 0.000
W00-W19 Falls
0.653 0.346 0.000
J60-J70 Lung diseases due to external agents
0.653 0.347 0.000
M20.3 Other deformity of hallux (acquired)
0.653 0.347 0.000
J45.8 Mixed asthma
0.653 0.347 0.000
J45.1 Nonallergic asthma
0.653 0.347 0.000
M54.98 Dorsalgia, unspecified (Sacral and sacrococcygeal region)
0.653 0.347 0.000
M54.97 Dorsalgia, unspecified (Lumbosacral region)
0.653 0.347 0.000
M54.95 Dorsalgia, unspecified (Thoracolumbar region)
0.653 0.347 0.000
M54.94 Dorsalgia, unspecified (Thoracic region)
0.653 0.347 0.000
M54.93 Dorsalgia, unspecified (Cervicothoracic region)
0.653 0.347 0.000
M54.92 Dorsalgia, unspecified (Cervical region)
0.653 0.347 0.000
M54.91 Dorsalgia, unspecified (Occipito-atlanto-axial region)
0.653 0.347 0.000
M54.90 Dorsalgia, unspecified (Multiple sites in spine)
0.653 0.347 0.000
J33 Nasal polyp
0.652 0.348 0.000
K76.7 Hepatorenal syndrome
0.651 0.349 0.000
K76.5 Hepatic veno-occlusive disease
0.651 0.349 0.000
K76.4 Peliosis hepatis
0.651 0.349 0.000
K76.3 Infarction of liver
0.651 0.349 0.000
K76.2 Central haemorrhagic necrosis of liver
0.651 0.349 0.000
K76.1 Chronic passive congestion of liver
0.651 0.349 0.000
H54.0 Blindness, both eyes
0.651 0.349 0.000
H54.7 Unspecified visual loss
0.651 0.349 0.000
H30-H36 Disorders of choroid and retina
0.650 0.350 0.000
N87.2 Severe cervical dysplasia, not elsewhere classified
0.650 0.350 0.000
M54.1 Radiculopathy
0.649 0.351 0.000
N92.6 Irregular menstruation, unspecified
0.649 0.351 0.000
H91.9 Hearing loss, unspecified
0.648 0.352 0.000
E86 Volume depletion
0.648 0.352 0.000
H72 Perforation of tympanic membrane
0.648 0.352 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.647 0.353 0.000
M54.38 Sciatica (Sacral and sacrococcygeal region)
0.647 0.353 0.000
M54.37 Sciatica (Lumbosacral region)
0.647 0.353 0.000
M54.35 Sciatica (Thoracolumbar region)
0.647 0.353 0.000
M54.34 Sciatica-Thoracic
0.647 0.353 0.000
M54.33 Sciatica-Cervicothoracic
0.647 0.353 0.000
M54.32 Sciatica-Cervical
0.647 0.353 0.000
M54.31 Sciatica-Occipit-atl-axl
0.647 0.353 0.000
M54.30 Sciatica (Multiple sites in spine)
0.647 0.353 0.000
N02 Recurrent and persistent haematuria
0.647 0.353 0.000
M54.55 Low back pain (Thoracolumbar region)
0.646 0.354 0.000
M54.54 Low back pain-Thoracic
0.646 0.354 0.000
M54.53 Low back pain-Cervicothoracic
0.646 0.354 0.000
M54.52 Low back pain-Cervical
0.646 0.354 0.000
M54.51 Low back pain-Occipit-atl-axl
0.646 0.354 0.000
M54.50 Low back pain (Multiple sites in spine)
0.646 0.354 0.000
T87 Complications peculiar to reattachment and amputation
0.646 0.354 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.646 0.354 0.000
T42.4 Benzodiazepines
0.646 0.354 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.646 0.354 0.000
J20-J22 Other acute lower respiratory infections
0.645 0.355 0.000
J82 Pulmonary eosinophilia, not elsewhere classified
0.644 0.356 0.000
K82.1 Hydrops of gallbladder
0.644 0.356 0.000
M51.3 Other specified intervertebral disk degeneration
0.644 0.356 0.000
M51.1 Lumbar and other intervertebral disk disorders with radiculopathy
0.644 0.356 0.000
M51.9 Intervertebral disk disorder, unspecified
0.644 0.356 0.000
M51.8 Other specified intervertebral disk disorders
0.644 0.356 0.000
M51.4 Schmorl's nodes
0.644 0.356 0.000
K82.8 Other specified diseases of gallbladder
0.643 0.357 0.000
E21.5 Disorder of parathyroid gland, unspecified
0.643 0.357 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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