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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16890376
log Bayes Factor = 13.4967
Chromosome 6   position 38,084,897  (GRCh37) Explore rs16890376 on Ensembl!
Variant rs16890376 is part of Cluster X0141

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
T36-T50 Poisoning by drugs, medicaments and biological substances
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
S00-S09 Injuries to the head
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter V Mental and behavioural disorders
0.999 0.001 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.997 0.003 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.997 0.003 0.000
T42 Poisoning by antiepileptic, sedative-hypnotic and anti-Parkinsonism drugs
0.993 0.007 0.000
S01 Open wound of head
0.992 0.008 0.000
F30-F39 Mood [affective] disorders
0.992 0.008 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.988 0.012 0.000
T51 Toxic effect of alcohol
0.987 0.013 0.000
G51 Facial nerve disorders
0.987 0.013 0.000
Chapter XX External causes of morbidity and mortality
0.987 0.013 0.000
Chapter VII Diseases of the eye and adnexa
0.984 0.016 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.980 0.020 0.000
S40-S49 Injuries to the shoulder and upper arm
0.979 0.021 0.000
S00 Superficial injury of head
0.979 0.021 0.000
T51.0 Ethanol
0.979 0.021 0.000
G51.0 Bell's palsy
0.977 0.023 0.000
T42.4 Benzodiazepines
0.972 0.028 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.970 0.030 0.000
G40-G47 Episodic and paroxysmal disorders
0.969 0.031 0.000
T43.5 Other and unspecified antipsychotics and neuroleptics
0.962 0.038 0.000
T66-T78 Other and unspecified effects of external causes
0.962 0.038 0.000
S20-S29 Injuries to the thorax
0.959 0.041 0.000
G57 Mononeuropathies of lower limb
0.959 0.041 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.956 0.044 0.000
G20-G26 Extrapyramidal and movement disorders
0.954 0.046 0.000
F33 Recurrent depressive disorder
0.953 0.047 0.000
S01.9 Open wound of head, part unspecified
0.948 0.052 0.000
T50.9 Other and unspecified drugs, medicaments and biological substances
0.948 0.052 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.945 0.055 0.000
S00.8 Superficial injury of other parts of head
0.943 0.057 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.939 0.061 0.000
F31 Bipolar affective disorder
0.935 0.065 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.935 0.065 0.000
G45.9 Transient cerebral ischaemic attack, unspecified
0.935 0.065 0.000
S50-S59 Injuries to the elbow and forearm
0.932 0.068 0.000
S42 Fracture of shoulder and upper arm
0.932 0.068 0.000
H55-H59 Other disorders of eye and adnexa
0.932 0.068 0.000
X20-X29 Contact with venomous animals and plants
0.929 0.071 0.000
S01.1 Open wound of eyelid and periocular area
0.924 0.076 0.000
S01.0 Open wound of scalp
0.923 0.077 0.000
T78 Adverse effects, not elsewhere classified
0.922 0.078 0.000
S42.2 Fracture of upper end of humerus
0.920 0.080 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.915 0.085 0.000
S42.20 Fracture of upper end of humerus (closed)
0.913 0.087 0.000
T42.6 Other antiepileptic and sedative-hypnotic drugs
0.909 0.091 0.000
Chapter VIII Diseases of the ear and mastoid process
0.906 0.094 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.905 0.095 0.000
T63 Toxic effect of contact with venomous animals
0.905 0.095 0.000
G90-G99 Other disorders of the nervous system
0.904 0.096 0.000
S90-S99 Injuries to the ankle and foot
0.904 0.096 0.000
G20 Parkinson's disease
0.903 0.097 0.000
G57.6 Lesion of plantar nerve
0.903 0.097 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.901 0.099 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.900 0.100 0.000
X23 Contact with hornets, wasps and bees
0.887 0.113 0.000
G59 Mononeuropathy in diseases classified elsewhere
0.885 0.115 0.000
H21 Other disorders of iris and ciliary body
0.883 0.117 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.881 0.119 0.000
F33.9 Recurrent depressive disorder, unspecified
0.876 0.124 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.874 0.126 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.874 0.126 0.000
T39.1 4-Aminophenol derivatives
0.873 0.127 0.000
G44 Other headache syndromes
0.873 0.127 0.000
X60-X84 Intentional self-harm
0.873 0.127 0.000
S05 Injury of eye and orbit
0.871 0.129 0.000
S00.0 Superficial injury of scalp
0.870 0.130 0.000
S92 Fracture of foot, except ankle
0.869 0.131 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.862 0.138 0.000
H49 Paralytic strabismus
0.856 0.144 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.855 0.145 0.000
F33.2 Recurrent depressive disorder, current episode severe without psychotic symptoms
0.855 0.145 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.855 0.145 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.854 0.146 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.848 0.152 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.847 0.153 0.000
S22.0 Fracture of thoracic vertebra
0.844 0.156 0.000
H57 Other disorders of eye and adnexa
0.842 0.158 0.000
T00-T07 Injuries involving multiple body regions
0.840 0.159 0.000
S70-S79 Injuries to the hip and thigh
0.840 0.160 0.000
H90-H95 Other disorders of ear
0.840 0.160 0.000
S01.4 Open wound of cheek and temporomandibular area
0.840 0.160 0.000
T63.4 Venom of other arthropods
0.839 0.161 0.000
S92.0 Fracture of calcaneus
0.837 0.163 0.000
F25 Schizoaffective disorders
0.837 0.163 0.000
S00.1 Contusion of eyelid and periocular area
0.835 0.165 0.000
S01.7 Multiple open wounds of head
0.835 0.165 0.000
S52 Fracture of forearm
0.833 0.167 0.000
T78.4 Allergy, unspecified
0.830 0.170 0.000
X23.9 Unspecified place
0.830 0.170 0.000
T43.2 Other and unspecified antidepressants
0.828 0.172 0.000
G44.2 Tension-type headache
0.827 0.173 0.000
F10.0 Acute intoxication
0.826 0.174 0.000
T78.0 Anaphylactic shock due to adverse food reaction
0.825 0.175 0.000
F17.1 Harmful use
0.824 0.176 0.000
T43.4 Butyrophenone and thioxanthene neuroleptics
0.820 0.180 0.000
G70-G73 Diseases of myoneural junction and muscle
0.818 0.182 0.000
G35 Multiple sclerosis
0.817 0.183 0.000
H43-H45 Disorders of vitreous body and globe
0.817 0.183 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.816 0.183 0.000
S92.00 Fracture of calcaneus (closed)
0.814 0.186 0.000
F30 Manic episode
0.814 0.186 0.000
H55 Nystagmus and other irregular eye movements
0.812 0.188 0.000
H65-H75 Diseases of middle ear and mastoid
0.812 0.188 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.811 0.189 0.000
W50-W64 Exposure to animate mechanical forces
0.810 0.190 0.000
H50 Other strabismus
0.808 0.192 0.000
F60-F69 Disorders of adult personality and behaviour
0.807 0.193 0.000
S49 Other and unspecified injuries of shoulder and upper arm
0.806 0.194 0.000
H20 Iridocyclitis
0.805 0.195 0.000
G59.0 Diabetic mononeuropathy
0.804 0.196 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.804 0.196 0.000
F31.0 Bipolar affective disorder, current episode hypomanic
0.803 0.197 0.000
F10.2 Dependence syndrome
0.803 0.197 0.000
S22.4 Multiple fractures of ribs
0.803 0.197 0.000
G95 Other diseases of spinal cord
0.803 0.197 0.000
G51.9 Disorder of facial nerve, unspecified
0.802 0.198 0.000
S22.00 Fracture of thoracic vertebra (closed)
0.800 0.200 0.000
S20 Superficial injury of thorax
0.798 0.202 0.000
G45.8 Other transient cerebral ischaemic attacks and related syndromes
0.797 0.203 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.796 0.204 0.000
S41 Open wound of shoulder and upper arm
0.795 0.205 0.000
V20-V29 Motorcycle rider injured in transport accident
0.792 0.208 0.000
G83 Other paralytic syndromes
0.791 0.208 0.000
S52.1 Fracture of upper end of radius
0.791 0.209 0.000
S00.2 Other superficial injuries of eyelid and periocular area
0.790 0.210 0.000
Y85 Sequelae of transport accidents
0.789 0.211 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.788 0.212 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.786 0.214 0.000
H21.8 Other specified disorders of iris and ciliary body
0.784 0.216 0.000
F33.4 Recurrent depressive disorder, currently in remission
0.784 0.216 0.000
G54 Nerve root and plexus disorders
0.783 0.217 0.000
V95-V97 Air and space transport accidents
0.782 0.218 0.000
T51.9 Alcohol, unspecified
0.782 0.218 0.000
G91 Hydrocephalus
0.780 0.220 0.000
G25 Other extrapyramidal and movement disorders
0.779 0.221 0.000
F10.3 Withdrawal state
0.779 0.221 0.000
H91 Other hearing loss
0.777 0.223 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.776 0.224 0.000
H57.1 Ocular pain
0.773 0.227 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.770 0.230 0.000
S50 Superficial injury of forearm
0.769 0.231 0.000
T40.2 Other opioids
0.767 0.233 0.000
S21 Open wound of thorax
0.767 0.233 0.000
T58 Toxic effect of carbon monoxide
0.766 0.234 0.000
H21.0 Hyphaema
0.765 0.235 0.000
T42.1 Iminostilbenes
0.765 0.235 0.000
T65 Toxic effect of other and unspecified substances
0.764 0.236 0.000
F31.4 Bipolar affective disorder, current episode severe depression without psychotic symptoms
0.761 0.239 0.000
S52.10 Fracture of upper end of radius (closed)
0.761 0.239 0.000
X23.0 Home
0.758 0.242 0.000
S09 Other and unspecified injuries of head
0.758 0.242 0.000
F99-F99 Unspecified mental disorder
0.756 0.244 0.000
T45.0 Antiallergic and antiemetic drugs
0.756 0.244 0.000
X68 Intentional self-poisoning by and exposure to pesticides
0.754 0.246 0.000
H49.0 Third [oculomotor] nerve palsy
0.752 0.248 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.752 0.248 0.000
Y85.0 Sequelae of motor-vehicle accident
0.752 0.248 0.000
S10-S19 Injuries to the neck
0.750 0.250 0.000
S02 Fracture of skull and facial bones
0.750 0.250 0.000
S56 Injury of muscle and tendon at forearm level
0.750 0.250 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.747 0.253 0.000
G57.8 Other mononeuropathies of lower limb
0.747 0.253 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.746 0.254 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.745 0.255 0.000
T68 Hypothermia
0.745 0.255 0.000
F31.2 Bipolar affective disorder, current episode manic with psychotic symptoms
0.745 0.255 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.744 0.256 0.000
H65 Nonsuppurative otitis media
0.743 0.257 0.000
S53 Dislocation, sprain and strain of joints and ligaments of elbow
0.742 0.258 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.741 0.259 0.000
F10.1 Harmful use
0.741 0.259 0.000
F31.7 Bipolar affective disorder, currently in remission
0.740 0.260 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.739 0.261 0.000
V98-V99 Other and unspecified transport accidents
0.739 0.261 0.000
H10-H13 Disorders of conjunctiva
0.737 0.262 0.000
H18 Other disorders of cornea
0.736 0.264 0.000
F31.1 Bipolar affective disorder, current episode manic without psychotic symptoms
0.734 0.266 0.000
G57.3 Lesion of lateral popliteal nerve
0.734 0.266 0.000
G45.1 Carotid artery syndrome (hemispheric)
0.733 0.267 0.000
T66 Unspecified effects of radiation
0.733 0.267 0.000
S00.7 Multiple superficial injuries of head
0.732 0.268 0.000
G83.4 Cauda equina syndrome
0.731 0.269 0.000
H91.9 Hearing loss, unspecified
0.731 0.269 0.000
T78.8 Other adverse effects, not elsewhere classified
0.730 0.270 0.000
S22.40 Multiple fractures of ribs (closed)
0.729 0.271 0.000
S76 Injury of muscle and tendon at hip and thigh level
0.728 0.272 0.000
S52.0 Fracture of upper end of ulna
0.728 0.272 0.000
T42.7 Antiepileptic and sedative-hypnotic drugs, unspecified
0.727 0.272 0.000
G51.8 Other disorders of facial nerve
0.727 0.273 0.000
F25.9 Schizoaffective disorder, unspecified
0.727 0.273 0.000
G80 Infantile cerebral palsy
0.726 0.274 0.000
G57.1 Meralgia paraesthetica
0.726 0.274 0.000
F31.9 Bipolar affective disorder, unspecified
0.725 0.275 0.000
T23 Burn and corrosion of wrist and hand
0.724 0.276 0.000
X62 Intentional self-poisoning by and exposure to narcotics and psychodysleptics [hallucinogens], not elsewhere classified
0.724 0.276 0.000
G41 Status epilepticus
0.721 0.278 0.000
F34 Persistent mood [affective] disorders
0.721 0.279 0.000
F31.5 Bipolar affective disorder, current episode severe depression with psychotic symptoms
0.720 0.280 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.720 0.280 0.000
F10.9 Unspecified mental and behavioural disorder
0.720 0.280 0.000
F32 Depressive episode
0.719 0.281 0.000
H59 Postprocedural disorders of eye and adnexa, not elsewhere classified
0.719 0.281 0.000
G72 Other myopathies
0.719 0.281 0.000
G45.4 Transient global amnesia
0.719 0.281 0.000
F70-F79 Mental retardation
0.719 0.281 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.717 0.283 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.717 0.283 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.717 0.283 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.717 0.283 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.717 0.283 0.000
T36 Poisoning by systemic antibiotics
0.717 0.283 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
S08 Traumatic amputation of part of head
0.717 0.283 0.000
S07 Crushing injury of head
0.717 0.283 0.000
S04 Injury of cranial nerves
0.717 0.283 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.716 0.283 0.000
S05.1 Contusion of eyeball and orbital tissues
0.716 0.284 0.000
G95.9 Disease of spinal cord, unspecified
0.716 0.284 0.000
G52 Disorders of other cranial nerves
0.715 0.285 0.000
T62 Toxic effect of other noxious substances eaten as food
0.714 0.285 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.714 0.285 0.000
T60 Toxic effect of pesticides
0.714 0.285 0.000
T57 Toxic effect of other inorganic substances
0.714 0.285 0.000
T54 Toxic effect of corrosive substances
0.714 0.285 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.714 0.285 0.000
T52 Toxic effect of organic solvents
0.714 0.285 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.714 0.285 0.000
T55 Toxic effect of soaps and detergents
0.714 0.285 0.000
T78.1 Other adverse food reactions, not elsewhere classified
0.714 0.286 0.000
F11 Mental and behavioural disorders due to use of opioids
0.714 0.286 0.000
G57.0 Lesion of sciatic nerve
0.713 0.287 0.000
T38.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.713 0.287 0.000
T56 Toxic effect of metals
0.712 0.288 0.000
T42.8 Anti-Parkinsonism drugs and other central muscle-tone depressants
0.712 0.288 0.000
T42.5 Mixed antiepileptics, not elsewhere classified
0.712 0.288 0.000
T42.3 Barbiturates
0.712 0.288 0.000
T42.2 Succinimides and oxazolidinediones
0.712 0.288 0.000
T42.0 Hydantoin derivatives
0.712 0.288 0.000
X50-X57 Overexertion, travel and privation
0.711 0.288 0.000
F38 Other mood [affective] disorders
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
F23 Acute and transient psychotic disorders
0.711 0.289 0.000
S42.0 Fracture of clavicle
0.710 0.290 0.000
V01-V09 Pedestrian injured in transport accident
0.710 0.290 0.000
S00.3 Superficial injury of nose
0.709 0.291 0.000
T43.9 Psychotropic drug, unspecified
0.709 0.291 0.000
T43.8 Other psychotropic drugs, not elsewhere classified
0.709 0.291 0.000
T43.6 Psychostimulants with abuse potential
0.709 0.291 0.000
T43.1 Monoamine-oxidase-inhibitor antidepressants
0.709 0.291 0.000
G95.8 Other specified diseases of spinal cord
0.708 0.292 0.000
T51.8 Other alcohols
0.708 0.292 0.000
T51.3 Fusel oil
0.708 0.292 0.000
T51.2 2-Propanol
0.708 0.292 0.000
T51.1 Methanol
0.708 0.292 0.000
G51.4 Facial myokymia
0.707 0.293 0.000
G51.2 Melkersson's syndrome
0.707 0.293 0.000
G51.1 Geniculate ganglionitis
0.707 0.293 0.000
Y35-Y36 Legal intervention and operations of war
0.707 0.293 0.000
Y10-Y34 Event of undetermined intent
0.707 0.293 0.000
X85-X99 Assault
0.707 0.293 0.000
X30-X39 Exposure to forces of nature
0.707 0.293 0.000
X00-X09 Exposure to smoke, fire and flames
0.707 0.293 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.707 0.293 0.000
W75-W84 Other accidental threats to breathing
0.707 0.293 0.000
W65-W74 Accidental drowning and submersion
0.707 0.293 0.000
V90-V94 Water transport accidents
0.707 0.293 0.000
V70-V79 Bus occupant injured in transport accident
0.707 0.293 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.707 0.293 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.707 0.293 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.707 0.293 0.000
X58 Exposure to other specified factors
0.706 0.294 0.000
G96 Other disorders of central nervous system
0.703 0.297 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.703 0.297 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.703 0.297 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.703 0.297 0.000
T20 Burn and corrosion of head and neck
0.702 0.298 0.000
S48 Traumatic amputation of shoulder and upper arm
0.702 0.298 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.702 0.298 0.000
S44 Injury of nerves at shoulder and upper arm level
0.702 0.298 0.000
S47 Crushing injury of shoulder and upper arm
0.702 0.298 0.000
G58 Other mononeuropathies
0.702 0.298 0.000
S00.4 Superficial injury of ear
0.702 0.298 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.701 0.299 0.000
X59 Exposure to unspecified factor
0.699 0.301 0.000
H90 Conductive and sensorineural hearing loss
0.698 0.302 0.000
S46.1 Injury of muscle and tendon of long head of biceps
0.697 0.303 0.000
H93 Other disorders of ear, not elsewhere classified
0.695 0.305 0.000
T50.8 Diagnostic agents
0.695 0.305 0.000
T50.7 Analeptics and opioid receptor antagonists
0.695 0.305 0.000
T50.6 Antidotes and chelating agents, not elsewhere classified
0.695 0.305 0.000
T50.5 Appetite depressants
0.695 0.305 0.000
T50.4 Drugs affecting uric acid metabolism
0.695 0.305 0.000
T50.3 Electrolytic, caloric and water-balance agents
0.695 0.305 0.000
T50.2 Carbonic-anhydrase inhibitors, benzothiadiazides and other diuretics
0.695 0.305 0.000
T50.1 Loop [high-ceiling] diuretics
0.695 0.305 0.000
T50.0 Mineralocorticoids and their antagonists
0.695 0.305 0.000
G57.5 Tarsal tunnel syndrome
0.694 0.305 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.694 0.305 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.694 0.306 0.000
H74 Other disorders of middle ear and mastoid
0.693 0.307 0.000
G53 Cranial nerve disorders in diseases classified elsewhere
0.693 0.307 0.000
T24.3 Burn of third degree of hip and lower limb, except ankle and foot
0.692 0.308 0.000
H49.9 Paralytic strabismus, unspecified
0.691 0.309 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.691 0.309 0.000
S22.2 Fracture of sternum
0.690 0.310 0.000
T74 Maltreatment syndromes
0.689 0.310 0.000
T73 Effects of other deprivation
0.689 0.310 0.000
T70 Effects of air pressure and water pressure
0.689 0.310 0.000
T69 Other effects of reduced temperature
0.689 0.310 0.000
T67 Effects of heat and light
0.689 0.310 0.000
T71 Asphyxiation
0.689 0.310 0.000
H52 Disorders of refraction and accommodation
0.689 0.311 0.000
G50 Disorders of trigeminal nerve
0.689 0.311 0.000
H57.0 Anomalies of pupillary function
0.689 0.311 0.000
G24 Dystonia
0.688 0.312 0.000
F60 Specific personality disorders
0.688 0.312 0.000
S28 Crushing injury of thorax and traumatic amputation of part of thorax
0.687 0.312 0.000
S26 Injury of heart
0.687 0.312 0.000
S25 Injury of blood vessels of thorax
0.687 0.312 0.000
S24 Injury of nerves and spinal cord at thorax level
0.687 0.312 0.000
S23 Dislocation, sprain and strain of joints and ligaments of thorax
0.687 0.312 0.000
G57.9 Mononeuropathy of lower limb, unspecified
0.687 0.313 0.000
G57.4 Lesion of medial popliteal nerve
0.687 0.313 0.000
G57.2 Lesion of femoral nerve
0.687 0.313 0.000
H65.2 Chronic serous otitis media
0.687 0.313 0.000
S99 Other and unspecified injuries of ankle and foot
0.686 0.314 0.000
G45.2 Multiple and bilateral precerebral artery syndromes
0.685 0.315 0.000
G45.0 Vertebro-basilar artery syndrome
0.685 0.315 0.000
S46.8 Injury of other muscles and tendons at shoulder and upper arm level
0.685 0.315 0.000
G23 Other degenerative diseases of basal ganglia
0.684 0.316 0.000
G21 Secondary Parkinsonism
0.684 0.316 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.684 0.316 0.000
G22 Parkinsonism in diseases classified elsewhere
0.684 0.316 0.000
T75 Effects of other external causes
0.684 0.316 0.000
F33.8 Other recurrent depressive disorders
0.683 0.316 0.000
F25.1 Schizoaffective disorder, depressive type
0.683 0.317 0.000
F25.0 Schizoaffective disorder, manic type
0.683 0.317 0.000
F80-F89 Disorders of psychological development
0.683 0.317 0.000
S49.9 Unspecified injury of shoulder and upper arm
0.682 0.318 0.000
F10.5 Psychotic disorder
0.682 0.318 0.000
F30.0 Hypomania
0.681 0.319 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.681 0.319 0.000
H15 Disorders of sclera
0.678 0.322 0.000
S05.3 Ocular laceration without prolapse or loss of intraocular tissue
0.677 0.322 0.000
S27 Injury of other and unspecified intrathoracic organs
0.677 0.323 0.000
S92.5 Fracture of other toe
0.677 0.323 0.000
G91.9 Hydrocephalus, unspecified
0.677 0.323 0.000
T38.1 Thyroid hormones and substitutes
0.677 0.323 0.000
H50.1 Divergent concomitant strabismus
0.677 0.323 0.000
X10-X19 Contact with heat and hot substances
0.676 0.324 0.000
F39 Unspecified mood [affective] disorder
0.676 0.324 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.675 0.324 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.675 0.325 0.000
G25.8 Other specified extrapyramidal and movement disorders
0.674 0.326 0.000
S71 Open wound of hip and thigh
0.674 0.326 0.000
G99.0 Autonomic neuropathy in endocrine and metabolic diseases
0.674 0.326 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.674 0.326 0.000
F10.8 Other mental and behavioural disorders
0.673 0.327 0.000
F10.7 Residual and late-onset psychotic disorder
0.673 0.327 0.000
F10.6 Amnesic syndrome
0.673 0.327 0.000
H57.9 Disorder of eye and adnexa, unspecified
0.673 0.327 0.000
G45.3 Amaurosis fugax
0.672 0.328 0.000
Y86 Sequelae of other accidents
0.672 0.328 0.000
S59 Other and unspecified injuries of forearm
0.671 0.328 0.000
F31.8 Other bipolar affective disorders
0.670 0.330 0.000
H51 Other disorders of binocular movement
0.670 0.330 0.000
X68.9 Unspecified place
0.670 0.330 0.000
S58 Traumatic amputation of forearm
0.668 0.331 0.000
S57 Crushing injury of forearm
0.668 0.331 0.000
S55 Injury of blood vessels at forearm level
0.668 0.331 0.000
S42.8 Fracture of other parts of shoulder and upper arm
0.668 0.332 0.000
S42.7 Multiple fractures of clavicle, scapula and humerus
0.668 0.332 0.000
T43.3 Phenothiazine antipsychotics and neuroleptics
0.668 0.332 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.668 0.332 0.000
T21 Burn and corrosion of trunk
0.666 0.334 0.000
X29 Contact with unspecified venomous animal or plant
0.666 0.334 0.000
X28 Contact with other specified venomous plants
0.666 0.334 0.000
X27 Contact with other specified venomous animals
0.666 0.334 0.000
X26 Contact with venomous marine animals and plants
0.666 0.334 0.000
X25 Contact with other specified venomous arthropods
0.666 0.334 0.000
X24 Contact with centipedes and venomous millipedes (tropical)
0.666 0.334 0.000
X22 Contact with scorpions
0.666 0.334 0.000
X21 Contact with venomous spiders
0.666 0.334 0.000
X20 Contact with venomous snakes and lizards
0.666 0.334 0.000
H50.8 Other specified strabismus
0.664 0.336 0.000
Y60 Unintentional cut, puncture, perforation or haemorrhage during surgical and medical care
0.663 0.337 0.000
T02 Fractures involving multiple body regions
0.663 0.337 0.000
V40-V49 Car occupant injured in transport accident
0.663 0.337 0.000
W20-W49 Exposure to inanimate mechanical forces
0.662 0.338 0.000
H49.2 Sixth [abducent] nerve palsy
0.662 0.338 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.661 0.339 0.000
T78.9 Adverse effect, unspecified
0.661 0.339 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.660 0.340 0.000
S42.21 Fracture of upper end of humerus (open)
0.660 0.340 0.000
G09 Sequelae of inflammatory diseases of central nervous system
0.659 0.341 0.000
F33.0 Recurrent depressive disorder, current episode mild
0.659 0.341 0.000
S92.7 Multiple fractures of foot
0.658 0.342 0.000
S96 Injury of muscle and tendon at ankle and foot level
0.657 0.343 0.000
F33.3 Recurrent depressive disorder, current episode severe with psychotic symptoms
0.657 0.343 0.000
S40 Superficial injury of shoulder and upper arm
0.656 0.344 0.000
T25 Burn and corrosion of ankle and foot
0.656 0.344 0.000
T59 Toxic effect of other gases, fumes and vapours
0.655 0.344 0.000
S92.3 Fracture of metatarsal bone
0.655 0.345 0.000
G43 Migraine
0.655 0.345 0.000
H20.8 Other iridocyclitis
0.655 0.345 0.000
H46 Optic neuritis
0.654 0.346 0.000
S52.00 Fracture of upper end of ulna (closed)
0.654 0.346 0.000
H43 Disorders of vitreous body
0.653 0.347 0.000
V27 Motorcycle rider injured in collision with fixed or stationary object
0.652 0.348 0.000
T01 Open wounds involving multiple body regions
0.651 0.348 0.000
S05.8 Other injuries of eye and orbit
0.651 0.348 0.000
H50.9 Strabismus, unspecified
0.650 0.350 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.649 0.351 0.000
S22.9 Fracture of bony thorax, part unspecified
0.649 0.351 0.000
S22.8 Fracture of other parts of bony thorax
0.649 0.351 0.000
R94 Abnormal results of function studies
0.649 0.351 0.000
T63.9 Toxic effect of contact with unspecified venomous animal
0.649 0.351 0.000
T63.8 Toxic effect of contact with other venomous animals
0.649 0.351 0.000
T63.6 Toxic effect of contact with other marine animals
0.649 0.351 0.000
T63.5 Toxic effect of contact with fish
0.649 0.351 0.000
T63.3 Venom of spider
0.649 0.351 0.000
T63.2 Venom of scorpion
0.649 0.351 0.000
T63.1 Venom of other reptiles
0.649 0.351 0.000
T63.0 Snake venom
0.649 0.351 0.000
S54 Injury of nerves at forearm level
0.648 0.352 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.648 0.352 0.000
G92 Toxic encephalopathy
0.648 0.352 0.000
F22 Persistent delusional disorders
0.648 0.352 0.000
T00 Superficial injuries involving multiple body regions
0.648 0.352 0.000
S76.4 Injury of other and unspecified muscles and tendons at thigh level
0.648 0.352 0.000
S98 Traumatic amputation of ankle and foot
0.648 0.352 0.000
S97 Crushing injury of ankle and foot
0.648 0.352 0.000
S95 Injury of blood vessels at ankle and foot level
0.648 0.352 0.000
S94 Injury of nerves at ankle and foot level
0.648 0.352 0.000
G51.3 Clonic hemifacial spasm
0.647 0.353 0.000
H44 Disorders of globe
0.647 0.353 0.000
W57 Bitten or stung by non-venomous insect and other non-venomous arthropods
0.646 0.354 0.000
F28 Other nonorganic psychotic disorders
0.646 0.354 0.000
F24 Induced delusional disorder
0.646 0.354 0.000
F21 Schizotypal disorder
0.646 0.354 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.646 0.354 0.000
T39.9 Nonopioid analgesic, antipyretic and antirheumatic, unspecified
0.645 0.354 0.000
T39.4 Antirheumatics, not elsewhere classified
0.645 0.354 0.000
T39.2 Pyrazolone derivatives
0.645 0.354 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.645 0.355 0.000
S20.1 Other and unspecified superficial injuries of breast
0.644 0.356 0.000
S20.2 Contusion of thorax
0.644 0.356 0.000
V80-V89 Other land transport accidents
0.643 0.357 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.642 0.358 0.000
H65.3 Chronic mucoid otitis media
0.642 0.358 0.000
H21.5 Other adhesions and disruptions of iris and ciliary body
0.640 0.360 0.000
S02.2 Fracture of nasal bones
0.639 0.361 0.000
T29 Burns and corrosions of multiple body regions
0.638 0.362 0.000
T78.2 Anaphylactic shock, unspecified
0.638 0.362 0.000
H02 Other disorders of eyelid
0.638 0.362 0.000
S41.0 Open wound of shoulder
0.637 0.363 0.000
S90 Superficial injury of ankle and foot
0.637 0.363 0.000
X23.8 Other specified place
0.636 0.364 0.000
X23.7 Farm
0.636 0.364 0.000
X23.6 Industrial and construction area
0.636 0.364 0.000
X23.5 Trade and service area
0.636 0.364 0.000
X23.4 Street and highway
0.636 0.364 0.000
X23.3 Sports and athletics area
0.636 0.364 0.000
X23.2 School, other institution and public administrative area
0.636 0.364 0.000
X23.1 Residential institution
0.636 0.364 0.000
V97 Other specified air transport accidents
0.636 0.364 0.000
H20.0 Acute and subacute iridocyclitis
0.636 0.364 0.000
R94.5 Abnormal results of liver function studies
0.636 0.364 0.000
T45.5 Anticoagulants
0.636 0.364 0.000
F31.6 Bipolar affective disorder, current episode mixed
0.635 0.365 0.000
G59.8 Other mononeuropathies in diseases classified elsewhere
0.634 0.366 0.000
H20.1 Chronic iridocyclitis
0.634 0.366 0.000
H16 Keratitis
0.633 0.367 0.000
W00-W19 Falls
0.633 0.367 0.000
F29 Unspecified nonorganic psychosis
0.633 0.367 0.000
H21.9 Disorder of iris and ciliary body, unspecified
0.633 0.367 0.000
H21.4 Pupillary membranes
0.633 0.367 0.000
H21.3 Cyst of iris, ciliary body and anterior chamber
0.633 0.367 0.000
H21.2 Degeneration of iris and ciliary body
0.633 0.367 0.000
H21.1 Other vascular disorders of iris and ciliary body
0.633 0.367 0.000
H90.0 Conductive hearing loss, bilateral
0.632 0.368 0.000
G36 Other acute disseminated demyelination
0.632 0.368 0.000
G54.6 Phantom limb syndrome with pain
0.632 0.368 0.000
F15.1 Harmful use
0.630 0.370 0.000
G44.4 Drug-induced headache, not elsewhere classified
0.630 0.370 0.000
S21.9 Open wound of thorax, part unspecified
0.629 0.371 0.000
H71 Cholesteatoma of middle ear
0.629 0.371 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.628 0.372 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.627 0.373 0.000
F17.9 Unspecified mental and behavioural disorder
0.626 0.374 0.000
F17.8 Other mental and behavioural disorders
0.626 0.374 0.000
F17.7 Residual and late-onset psychotic disorder
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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