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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16964886
log Bayes Factor = 2.33933
Chromosome 18   position 31,321,994  (GRCh37) Explore rs16964886 on Ensembl!
Variant rs16964886 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.992 0.008 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.991 0.009 0.000
Chapter XI Diseases of the digestive system
0.989 0.011 0.000
I20-I25 Ischaemic heart diseases
0.989 0.011 0.000
K29 Gastritis and duodenitis
0.988 0.012 0.000
Chapter II Neoplasms
0.983 0.017 0.000
K29.7 Gastritis, unspecified
0.978 0.022 0.000
I25 Chronic ischaemic heart disease
0.973 0.027 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.973 0.027 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.953 0.047 0.000
Chapter X Diseases of the respiratory system
0.952 0.048 0.000
C79 Secondary malignant neoplasm of other sites
0.934 0.066 0.000
I10-I15 Hypertensive diseases
0.932 0.068 0.000
I25.2 Old myocardial infarction
0.931 0.069 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.923 0.077 0.000
K22 Other diseases of oesophagus
0.902 0.098 0.000
D50-D53 Nutritional anaemias
0.893 0.107 0.000
J20-J22 Other acute lower respiratory infections
0.888 0.112 0.000
I10 Essential (primary) hypertension
0.883 0.117 0.000
I25.8 Other forms of chronic ischaemic heart disease
0.883 0.117 0.000
C15-C26 Malignant neoplasms of digestive organs
0.874 0.126 0.000
Chapter VIII Diseases of the ear and mastoid process
0.870 0.130 0.000
I20 Angina pectoris
0.869 0.131 0.000
J30-J39 Other diseases of upper respiratory tract
0.868 0.132 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.868 0.132 0.000
K21 Gastro-oesophageal reflux disease
0.863 0.137 0.000
K25 Gastric ulcer
0.861 0.139 0.000
D50 Iron deficiency anaemia
0.858 0.142 0.000
K29.6 Other gastritis
0.855 0.145 0.000
J22 Unspecified acute lower respiratory infection
0.843 0.157 0.000
K29.8 Duodenitis
0.838 0.162 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.830 0.170 0.000
C79.2 Secondary malignant neoplasm of skin
0.830 0.170 0.000
I21 Acute myocardial infarction
0.825 0.175 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.822 0.178 0.000
D60-D64 Aplastic and other anaemias
0.822 0.178 0.000
I22 Subsequent myocardial infarction
0.819 0.180 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.819 0.181 0.000
Chapter I Certain infectious and parasitic diseases
0.818 0.182 0.000
C78.2 Secondary malignant neoplasm of pleura
0.817 0.183 0.000
D50.8 Other iron deficiency anaemias
0.802 0.198 0.000
C78.7 Secondary malignant neoplasm of liver
0.799 0.201 0.000
C78.6 Secondary malignant neoplasm of retroperitoneum and peritoneum
0.797 0.203 0.000
J60-J70 Lung diseases due to external agents
0.797 0.203 0.000
K26 Duodenal ulcer
0.796 0.203 0.000
I30-I52 Other forms of heart disease
0.796 0.204 0.000
C20 Malignant neoplasm of rectum
0.796 0.204 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.788 0.212 0.000
J00-J06 Acute upper respiratory infections
0.787 0.213 0.000
J30 Vasomotor and allergic rhinitis
0.784 0.216 0.000
K70-K77 Diseases of liver
0.784 0.216 0.000
K29.3 Chronic superficial gastritis
0.781 0.219 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.781 0.219 0.000
H80-H83 Diseases of inner ear
0.773 0.227 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.772 0.228 0.000
D50.9 Iron deficiency anaemia, unspecified
0.768 0.232 0.000
I20.9 Angina pectoris, unspecified
0.765 0.235 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.762 0.238 0.000
K27 Peptic ulcer, site unspecified
0.759 0.241 0.000
C15 Malignant neoplasm of oesophagus
0.758 0.242 0.000
K50-K52 Noninfective enteritis and colitis
0.755 0.245 0.000
I25.1 Atherosclerotic heart disease
0.755 0.245 0.000
S80-S89 Injuries to the knee and lower leg
0.753 0.247 0.000
K29.0 Acute haemorrhagic gastritis
0.752 0.248 0.000
K22.9 Disease of oesophagus, unspecified
0.748 0.252 0.000
I24 Other acute ischaemic heart diseases
0.745 0.255 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.744 0.256 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.743 0.257 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.739 0.261 0.000
S00-S09 Injuries to the head
0.736 0.264 0.000
K65-K67 Diseases of peritoneum
0.732 0.268 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.732 0.268 0.000
K22.2 Oesophageal obstruction
0.728 0.272 0.000
H65-H75 Diseases of middle ear and mastoid
0.724 0.275 0.000
J30.1 Allergic rhinitis due to pollen
0.724 0.276 0.000
C60-C63 Malignant neoplasms of male genital organs
0.723 0.277 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.723 0.277 0.000
Chapter XXII Codes for special purposes
0.720 0.280 0.000
C64-C68 Malignant neoplasms of urinary tract
0.719 0.281 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.718 0.282 0.000
K31 Other diseases of stomach and duodenum
0.715 0.284 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.715 0.285 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.712 0.288 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
K28 Gastrojejunal ulcer
0.710 0.290 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.710 0.290 0.000
I23 Certain current complications following acute myocardial infarction
0.709 0.291 0.000
K29.9 Gastroduodenitis, unspecified
0.708 0.291 0.000
K29.4 Chronic atrophic gastritis
0.708 0.291 0.000
K29.2 Alcoholic gastritis
0.708 0.291 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.705 0.295 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.705 0.295 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.705 0.295 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.705 0.295 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.705 0.295 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.705 0.295 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.705 0.295 0.000
D64 Other anaemias
0.705 0.295 0.000
C80 Malignant neoplasm without specification of site
0.703 0.297 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.699 0.301 0.000
I44 Atrioventricular and left bundle-branch block
0.699 0.301 0.000
I25.6 Silent myocardial ischaemia
0.698 0.302 0.000
I25.5 Ischaemic cardiomyopathy
0.698 0.302 0.000
I25.4 Coronary artery aneurysm
0.698 0.302 0.000
I25.3 Aneurysm of heart
0.698 0.302 0.000
I25.0 Atherosclerotic cardiovascular disease, so described
0.698 0.302 0.000
I22.9 Subsequent myocardial infarction of unspecified site
0.698 0.302 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.698 0.302 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.696 0.304 0.000
I12 Hypertensive renal disease
0.696 0.304 0.000
K29.5 Chronic gastritis, unspecified
0.694 0.306 0.000
I21.4 Acute subendocardial myocardial infarction
0.690 0.310 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.689 0.311 0.000
H81 Disorders of vestibular function
0.688 0.311 0.000
I25.9 Chronic ischaemic heart disease, unspecified
0.685 0.314 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.685 0.315 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.685 0.315 0.000
K22.7 Barrett's oesophagus
0.684 0.316 0.000
D80-D89 Certain disorders involving the immune mechanism
0.683 0.317 0.000
D55-D59 Haemolytic anaemias
0.683 0.317 0.000
J95-J99 Other diseases of the respiratory system
0.674 0.326 0.000
I51 Complications and ill-defined descriptions of heart disease
0.674 0.326 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.673 0.326 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.670 0.330 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.670 0.330 0.000
C79.6 Secondary malignant neoplasm of ovary
0.670 0.330 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.670 0.330 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.670 0.330 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.670 0.330 0.000
B35-B49 Mycoses
0.669 0.331 0.000
D45 Polycythaemia vera
0.669 0.331 0.000
K90-K93 Other diseases of the digestive system
0.668 0.332 0.000
B07 Viral warts
0.668 0.332 0.000
I15 Secondary hypertension
0.668 0.332 0.000
I13 Hypertensive heart and renal disease
0.668 0.332 0.000
I11 Hypertensive heart disease
0.668 0.332 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.667 0.333 0.000
I05-I09 Chronic rheumatic heart diseases
0.666 0.334 0.000
K20 Oesophagitis
0.665 0.335 0.000
K25.3 Acute without haemorrhage or perforation
0.664 0.336 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.663 0.337 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.662 0.337 0.000
K22.8 Other specified diseases of oesophagus
0.662 0.338 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.662 0.338 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.662 0.338 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.662 0.338 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.662 0.338 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.662 0.338 0.000
K22.4 Dyskinesia of oesophagus
0.662 0.338 0.000
K29.1 Other acute gastritis
0.662 0.338 0.000
K14 Diseases of tongue
0.661 0.339 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.660 0.340 0.000
K22.1 Ulcer of oesophagus
0.660 0.340 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.657 0.343 0.000
I21.0 Acute transmural myocardial infarction of anterior wall
0.656 0.344 0.000
D00-D09 In situ neoplasms
0.655 0.344 0.000
Chapter VII Diseases of the eye and adnexa
0.655 0.345 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.653 0.347 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.653 0.347 0.000
J00 Acute nasopharyngitis [common cold]
0.652 0.348 0.000
I20.0 Unstable angina
0.650 0.350 0.000
J35 Chronic diseases of tonsils and adenoids
0.648 0.352 0.000
I60-I69 Cerebrovascular diseases
0.648 0.352 0.000
K35-K38 Diseases of appendix
0.648 0.352 0.000
J39 Other diseases of upper respiratory tract
0.647 0.353 0.000
K22.5 Diverticulum of oesophagus, acquired
0.646 0.353 0.000
K22.3 Perforation of oesophagus
0.646 0.353 0.000
K22.0 Achalasia of cardia
0.646 0.353 0.000
J32 Chronic sinusitis
0.645 0.354 0.000
C15.9 Oesophagus, unspecified
0.643 0.357 0.000
J90-J94 Other diseases of pleura
0.643 0.357 0.000
K26.4 Chronic or unspecified with haemorrhage
0.642 0.358 0.000
I45 Other conduction disorders
0.641 0.358 0.000
K51 Ulcerative colitis
0.641 0.359 0.000
D53 Other nutritional anaemias
0.640 0.360 0.000
D52 Folate deficiency anaemia
0.640 0.360 0.000
I34 Nonrheumatic mitral valve disorders
0.640 0.360 0.000
I20.8 Other forms of angina pectoris
0.639 0.360 0.000
J33 Nasal polyp
0.638 0.362 0.000
S70-S79 Injuries to the hip and thigh
0.637 0.363 0.000
J21 Acute bronchiolitis
0.637 0.363 0.000
J20 Acute bronchitis
0.637 0.363 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.637 0.363 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.635 0.365 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.634 0.366 0.000
K25.7 Chronic without haemorrhage or perforation
0.633 0.367 0.000
Chapter V Mental and behavioural disorders
0.632 0.368 0.000
D61 Other aplastic anaemias
0.629 0.371 0.000
H81.0 Meniere's disease
0.628 0.372 0.000
I21.9 Acute myocardial infarction, unspecified
0.627 0.373 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.627 0.373 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.627 0.373 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.627 0.373 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.627 0.373 0.000
C21 Malignant neoplasm of anus and anal canal
0.627 0.373 0.000
C17 Malignant neoplasm of small intestine
0.627 0.373 0.000
C16 Malignant neoplasm of stomach
0.627 0.373 0.000
C23 Malignant neoplasm of gallbladder
0.627 0.373 0.000
J09-J18 Influenza and pneumonia
0.626 0.374 0.000
I20.1 Angina pectoris with documented spasm
0.623 0.377 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.623 0.377 0.000
J37 Chronic laryngitis and laryngotracheitis
0.623 0.377 0.000
J36 Peritonsillar abscess
0.623 0.377 0.000
C51-C58 Malignant neoplasms of female genital organs
0.622 0.378 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.622 0.378 0.000
T79-T79 Certain early complications of trauma
0.622 0.378 0.000
T33-T35 Frostbite
0.622 0.378 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.622 0.378 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.622 0.378 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.622 0.378 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.622 0.378 0.000
T00-T07 Injuries involving multiple body regions
0.622 0.378 0.000
S10-S19 Injuries to the neck
0.622 0.378 0.000
S40-S49 Injuries to the shoulder and upper arm
0.621 0.378 0.000
S90-S99 Injuries to the ankle and foot
0.621 0.379 0.000
D64.9 Anaemia, unspecified
0.621 0.379 0.000
C34 Malignant neoplasm of bronchus and lung
0.620 0.380 0.000
S50-S59 Injuries to the elbow and forearm
0.620 0.380 0.000
C25 Malignant neoplasm of pancreas
0.619 0.381 0.000
D46 Myelodysplastic syndromes
0.618 0.382 0.000
A30-A49 Other bacterial diseases
0.618 0.382 0.000
K25.6 Chronic or unspecified with both haemorrhage and perforation
0.617 0.382 0.000
K25.5 Chronic or unspecified with perforation
0.617 0.382 0.000
K25.4 Chronic or unspecified with haemorrhage
0.617 0.382 0.000
K25.2 Acute with both haemorrhage and perforation
0.617 0.382 0.000
K25.1 Acute with perforation
0.617 0.382 0.000
K25.0 Acute with haemorrhage
0.617 0.382 0.000
D50.1 Sideropenic dysphagia
0.615 0.385 0.000
I24.9 Acute ischaemic heart disease, unspecified
0.615 0.385 0.000
J69 Pneumonitis due to solids and liquids
0.615 0.385 0.000
C43 Malignant melanoma of skin
0.610 0.390 0.000
H60-H62 Diseases of external ear
0.605 0.395 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.604 0.396 0.000
C15.5 Lower third of oesophagus
0.602 0.398 0.000
K04 Diseases of pulp and periapical tissues
0.602 0.398 0.000
T66-T78 Other and unspecified effects of external causes
0.601 0.399 0.000
K31.9 Disease of stomach and duodenum, unspecified
0.601 0.399 0.000
K76 Other diseases of liver
0.597 0.403 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.596 0.404 0.000
C90 Multiple myeloma and malignant plasma cell neoplasms
0.595 0.404 0.000
J02 Acute pharyngitis
0.595 0.405 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.595 0.405 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.595 0.405 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.595 0.405 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.595 0.405 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.595 0.405 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.595 0.405 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.595 0.405 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.595 0.405 0.000
H72 Perforation of tympanic membrane
0.595 0.405 0.000
S83 Dislocation, sprain and strain of joints and ligaments of knee
0.595 0.405 0.000
H83 Other diseases of inner ear
0.594 0.406 0.000
K26.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.594 0.406 0.000
S80 Superficial injury of lower leg
0.594 0.406 0.000
B02 Zoster [herpes zoster]
0.594 0.406 0.000
K70 Alcoholic liver disease
0.593 0.407 0.000
M45-M49 Spondylopathies
0.593 0.407 0.000
K27.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.593 0.407 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.593 0.407 0.000
C44 Other malignant neoplasms of skin
0.592 0.408 0.000
I42 Cardiomyopathy
0.592 0.408 0.000
I21.X Presumed acute myicardial infaction (unconfirmed)
0.591 0.409 0.000
I21.3 Acute transmural myocardial infarction of unspecified site
0.591 0.409 0.000
I21.2 Acute transmural myocardial infarction of other sites
0.591 0.409 0.000
K12 Stomatitis and related lesions
0.591 0.409 0.000
S00 Superficial injury of head
0.590 0.410 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.589 0.411 0.000
D62 Acute posthaemorrhagic anaemia
0.589 0.411 0.000
O00-O08 Pregnancy with abortive outcome
0.589 0.411 0.000
K14.8 Other diseases of tongue
0.589 0.411 0.000
I22.8 Subsequent myocardial infarction of other sites
0.588 0.412 0.000
I22.1 Subsequent myocardial infarction of inferior wall
0.588 0.412 0.000
I22.0 Subsequent myocardial infarction of anterior wall
0.588 0.412 0.000
B99-B99 Other infectious diseases
0.586 0.413 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.586 0.413 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.586 0.413 0.000
B65-B83 Helminthiases
0.586 0.413 0.000
B50-B64 Protozoal diseases
0.586 0.413 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.586 0.413 0.000
B15-B19 Viral hepatitis
0.586 0.413 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.586 0.413 0.000
A80-A89 Viral infections of the central nervous system
0.586 0.413 0.000
A75-A79 Rickettsioses
0.586 0.413 0.000
A70-A74 Other diseases caused by chlamydiae
0.586 0.413 0.000
A65-A69 Other spirochaetal diseases
0.586 0.413 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.586 0.413 0.000
A20-A28 Certain zoonotic bacterial diseases
0.586 0.413 0.000
A15-A19 Tuberculosis
0.586 0.413 0.000
S01 Open wound of head
0.586 0.414 0.000
J03 Acute tonsillitis
0.585 0.414 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.585 0.415 0.000
M05-M14 Inflammatory polyarthropathies
0.584 0.416 0.000
S82 Fracture of lower leg, including ankle
0.582 0.418 0.000
S20-S29 Injuries to the thorax
0.582 0.418 0.000
O99 Other maternal diseases classifiable elsewhere but complicating pregnancy, childbirth and the puerperium
0.581 0.419 0.000
K74 Fibrosis and cirrhosis of liver
0.580 0.420 0.000
C64 Malignant neoplasm of kidney, except renal pelvis
0.580 0.420 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.579 0.421 0.000
I80 Phlebitis and thrombophlebitis
0.578 0.422 0.000
I38 Endocarditis, valve unspecified
0.578 0.422 0.000
D51 Vitamin B12 deficiency anaemia
0.577 0.422 0.000
M70-M79 Other soft tissue disorders
0.576 0.424 0.000
J31.0 Chronic rhinitis
0.573 0.427 0.000
S60-S69 Injuries to the wrist and hand
0.573 0.427 0.000
J70 Respiratory conditions due to other external agents
0.571 0.428 0.000
J68 Respiratory conditions due to inhalation of chemicals, gases, fumes and vapours
0.571 0.428 0.000
J67 Hypersensitivity pneumonitis due to organic dust
0.571 0.428 0.000
J66 Airway disease due to specific organic dust
0.571 0.428 0.000
J63 Pneumoconiosis due to other inorganic dusts
0.571 0.428 0.000
J62 Pneumoconiosis due to dust containing silica
0.571 0.428 0.000
J65 Pneumoconiosis associated with tuberculosis
0.571 0.428 0.000
J64 Unspecified pneumoconiosis
0.571 0.428 0.000
J60 Coalworker's pneumoconiosis
0.571 0.428 0.000
K26.7 Chronic without haemorrhage or perforation
0.571 0.429 0.000
K26.6 Chronic or unspecified with both haemorrhage and perforation
0.571 0.429 0.000
K26.5 Chronic or unspecified with perforation
0.571 0.429 0.000
K26.3 Acute without haemorrhage or perforation
0.571 0.429 0.000
K26.2 Acute with both haemorrhage and perforation
0.571 0.429 0.000
K26.1 Acute with perforation
0.571 0.429 0.000
K26.0 Acute with haemorrhage
0.571 0.429 0.000
I52 Other heart disorders in diseases classified elsewhere
0.571 0.429 0.000
I48 Atrial fibrillation and flutter
0.571 0.429 0.000
I43 Cardiomyopathy in diseases classified elsewhere
0.571 0.429 0.000
I41 Myocarditis in diseases classified elsewhere
0.571 0.429 0.000
I40 Acute myocarditis
0.571 0.429 0.000
I39 Endocarditis and heart valve disorders in diseases classified elsewhere
0.571 0.429 0.000
I37 Pulmonary valve disorders
0.571 0.429 0.000
I36 Nonrheumatic tricuspid valve disorders
0.571 0.429 0.000
I33 Acute and subacute endocarditis
0.571 0.429 0.000
I32 Pericarditis in diseases classified elsewhere
0.571 0.429 0.000
I30 Acute pericarditis
0.571 0.429 0.000
I49 Other cardiac arrhythmias
0.571 0.429 0.000
M40-M43 Deforming dorsopathies
0.570 0.430 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.569 0.431 0.000
S81 Open wound of lower leg
0.569 0.431 0.000
D50.0 Iron deficiency anaemia secondary to blood loss (chronic)
0.565 0.435 0.000
O80-O84 Delivery
0.565 0.435 0.000
O85-O92 Complications predominantly related to the puerperium
0.565 0.435 0.000
J05 Acute obstructive laryngitis [croup] and epiglottitis
0.564 0.436 0.000
J04 Acute laryngitis and tracheitis
0.564 0.436 0.000
J01 Acute sinusitis
0.564 0.436 0.000
H71 Cholesteatoma of middle ear
0.563 0.437 0.000
Q60-Q64 Congenital malformations of the urinary system
0.563 0.437 0.000
M80-M85 Disorders of bone density and structure
0.563 0.437 0.000
J30.4 Allergic rhinitis, unspecified
0.562 0.437 0.000
J30.3 Other allergic rhinitis
0.562 0.437 0.000
J30.2 Other seasonal allergic rhinitis
0.562 0.437 0.000
J30.0 Vasomotor rhinitis
0.562 0.437 0.000
B37 Candidiasis
0.562 0.438 0.000
K77 Liver disorders in diseases classified elsewhere
0.562 0.438 0.000
K75 Other inflammatory liver diseases
0.562 0.438 0.000
K73 Chronic hepatitis, not elsewhere classified
0.562 0.438 0.000
K72 Hepatic failure, not elsewhere classified
0.562 0.438 0.000
K71 Toxic liver disease
0.562 0.438 0.000
O36 Maternal care for other known or suspected foetal problems
0.562 0.438 0.000
I44.1 Atrioventricular block, second degree
0.559 0.441 0.000
I44.7 Left bundle-branch block, unspecified
0.558 0.442 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.558 0.442 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.556 0.444 0.000
S02 Fracture of skull and facial bones
0.556 0.444 0.000
D68 Other coagulation defects
0.555 0.445 0.000
H80 Otosclerosis
0.554 0.445 0.000
H82 Vertiginous syndromes in diseases classified elsewhere
0.554 0.445 0.000
O42 Premature rupture of membranes
0.554 0.446 0.000
M86-M90 Other osteopathies
0.554 0.446 0.000
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
0.553 0.446 0.000
C38 Malignant neoplasm of heart, mediastinum and pleura
0.553 0.446 0.000
C32 Malignant neoplasm of larynx
0.553 0.446 0.000
C31 Malignant neoplasm of accessory sinuses
0.553 0.446 0.000
C30 Malignant neoplasm of nasal cavity and middle ear
0.553 0.446 0.000
C37 Malignant neoplasm of thymus
0.553 0.446 0.000
C33 Malignant neoplasm of trachea
0.553 0.446 0.000
Chapter XX External causes of morbidity and mortality
0.553 0.447 0.000
J33.0 Polyp of nasal cavity
0.552 0.447 0.000
C43.5 Malignant melanoma of trunk
0.551 0.449 0.000
K92 Other diseases of digestive system
0.551 0.449 0.000
D37.7 Other digestive organs
0.550 0.450 0.000
I83 Varicose veins of lower extremities
0.550 0.450 0.000
K50 Crohn's disease [regional enteritis]
0.550 0.450 0.000
I44.2 Atrioventricular block, complete
0.549 0.451 0.000
I51.9 Heart disease, unspecified
0.548 0.452 0.000
I47 Paroxysmal tachycardia
0.548 0.452 0.000
O34 Maternal care for known or suspected abnormality of pelvic organs
0.547 0.453 0.000
K11 Diseases of salivary glands
0.547 0.453 0.000
K10 Other diseases of jaws
0.547 0.453 0.000
K09 Cysts of oral region, not elsewhere classified
0.547 0.453 0.000
K07 Dentofacial anomalies [including malocclusion]
0.547 0.453 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.547 0.453 0.000
K03 Other diseases of hard tissues of teeth
0.547 0.453 0.000
K00 Disorders of tooth development and eruption
0.547 0.453 0.000
K27.7 Chronic without haemorrhage or perforation
0.544 0.456 0.000
K27.6 Chronic or unspecified with both haemorrhage and perforation
0.544 0.456 0.000
K27.5 Chronic or unspecified with perforation
0.544 0.456 0.000
K27.4 Chronic or unspecified with haemorrhage
0.544 0.456 0.000
K27.3 Acute without haemorrhage or perforation
0.544 0.456 0.000
K27.2 Acute with both haemorrhage and perforation
0.544 0.456 0.000
K27.1 Acute with perforation
0.544 0.456 0.000
K27.0 Acute with haemorrhage
0.544 0.456 0.000
C15.8 Overlapping lesion of oesophagus
0.543 0.456 0.000
C15.4 Middle third of oesophagus
0.543 0.456 0.000
C15.3 Upper third of oesophagus
0.543 0.456 0.000
C15.2 Abdominal part of oesophagus
0.543 0.456 0.000
C15.1 Thoracic part of oesophagus
0.543 0.456 0.000
C15.0 Cervical part of oesophagus
0.543 0.456 0.000
I63 Cerebral infarction
0.543 0.457 0.000
C50-C50 Malignant neoplasm of breast
0.542 0.458 0.000
I34.0 Mitral (valve) insufficiency
0.541 0.459 0.000
S89 Other and unspecified injuries of lower leg
0.540 0.460 0.000
S88 Traumatic amputation of lower leg
0.540 0.460 0.000
S87 Crushing injury of lower leg
0.540 0.460 0.000
S86 Injury of muscle and tendon at lower leg level
0.540 0.460 0.000
S85 Injury of blood vessels at lower leg level
0.540 0.460 0.000
S84 Injury of nerves at lower leg level
0.540 0.460 0.000
K65 Peritonitis
0.537 0.463 0.000
I98 Other disorders of circulatory system in diseases classified elsewhere
0.537 0.463 0.000
K01 Embedded and impacted teeth
0.536 0.463 0.000
C61 Malignant neoplasm of prostate
0.536 0.464 0.000
J06 Acute upper respiratory infections of multiple and unspecified sites
0.536 0.464 0.000
K66 Other disorders of peritoneum
0.536 0.464 0.000
I24.1 Dressler's syndrome
0.534 0.466 0.000
I24.0 Coronary thrombosis not resulting in myocardial infarction
0.534 0.466 0.000
C77.4 Inguinal and lower limb lymph nodes
0.534 0.466 0.000
C78.0 Secondary malignant neoplasm of lung
0.534 0.466 0.000
B08 Other viral infections characterised by skin and mucous membrane lesions, not elsewhere classified
0.533 0.467 0.000
B06 Rubella [German measles]
0.533 0.467 0.000
B05 Measles
0.533 0.467 0.000
B01 Varicella [chickenpox]
0.533 0.467 0.000
B00 Herpesviral [herpes simplex] infections
0.533 0.467 0.000
B09 Unspecified viral infection characterised by skin and mucous membrane lesions
0.533 0.467 0.000
B04 Monkeypox
0.533 0.467 0.000
B03 Smallpox
0.533 0.467 0.000
H65 Nonsuppurative otitis media
0.532 0.468 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.531 0.469 0.000
J39.8 Other specified diseases of upper respiratory tract
0.530 0.470 0.000
I61 Intracerebral haemorrhage
0.530 0.470 0.000
C77.3 Axillary and upper limb lymph nodes
0.529 0.471 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.528 0.472 0.000
S08 Traumatic amputation of part of head
0.527 0.472 0.000
S07 Crushing injury of head
0.527 0.472 0.000
S06 Intracranial injury
0.527 0.472 0.000
S05 Injury of eye and orbit
0.527 0.472 0.000
S04 Injury of cranial nerves
0.527 0.472 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.527 0.472 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.527 0.473 0.000
I12.0 Hypertensive renal disease with renal failure
0.527 0.473 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.525 0.475 0.000
B95-B98 Bacterial, viral and other infectious agents
0.525 0.475 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.525 0.475 0.000
Q80-Q89 Other congenital malformations
0.525 0.475 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.525 0.475 0.000
Q50-Q56 Congenital malformations of genital organs
0.525 0.475 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.525 0.475 0.000
Q35-Q37 Cleft lip and cleft palate
0.525 0.475 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.525 0.475 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.525 0.475 0.000
Q00-Q07 Congenital malformations of the nervous system
0.525 0.475 0.000
B25-B34 Other viral diseases
0.524 0.475 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.524 0.475 0.000
F30-F39 Mood [affective] disorders
0.524 0.476 0.000
K51.9 Ulcerative colitis, unspecified
0.523 0.477 0.000
J32.2 Chronic ethmoidal sinusitis
0.521 0.478 0.000
C90.0 Multiple myeloma
0.521 0.479 0.000
H52 Disorders of refraction and accommodation
0.521 0.479 0.000
I45.6 Preexcitation syndrome
0.520 0.480 0.000
H75 Other disorders of middle ear and mastoid in diseases classified elsewhere
0.519 0.480 0.000
H74 Other disorders of middle ear and mastoid
0.519 0.480 0.000
H73 Other disorders of tympanic membrane
0.519 0.480 0.000
H70 Mastoiditis and related conditions
0.519 0.480 0.000
H69 Other disorders of Eustachian tube
0.519 0.480 0.000
H68 Eustachian salpingitis and obstruction
0.519 0.480 0.000
H67 Otitis media in diseases classified elsewhere
0.519 0.480 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.518 0.481 0.000
C62 Malignant neoplasm of testis
0.518 0.481 0.000
C60 Malignant neoplasm of penis
0.518 0.481 0.000
I88 Nonspecific lymphadenitis
0.518 0.482 0.000
I87 Other disorders of veins
0.518 0.482 0.000
I86 Varicose veins of other sites
0.518 0.482 0.000
I82 Other venous embolism and thrombosis
0.518 0.482 0.000
I81 Portal vein thrombosis
0.518 0.482 0.000
I31 Other diseases of pericardium
0.518 0.482 0.000
S09 Other and unspecified injuries of head
0.518 0.482 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.516 0.483 0.000
K51.2 Ulcerative (chronic) proctitis
0.516 0.484 0.000
H90-H95 Other disorders of ear
0.516 0.484 0.000
I51.8 Other ill-defined heart diseases
0.516 0.484 0.000
C68 Malignant neoplasm of other and unspecified urinary organs
0.515 0.485 0.000
C66 Malignant neoplasm of ureter
0.515 0.485 0.000
C65 Malignant neoplasm of renal pelvis
0.515 0.485 0.000
M91-M94 Chondropathies
0.515 0.485 0.000
M60-M63 Disorders of muscles
0.515 0.485 0.000
M00-M03 Infectious arthropathies
0.515 0.485 0.000
I51.7 Cardiomegaly
0.515 0.485 0.000
K31.6 Fistula of stomach and duodenum
0.513 0.487 0.000
K31.5 Obstruction of duodenum
0.513 0.487 0.000
K31.4 Gastric diverticulum
0.513 0.487 0.000
K31.3 Pylorospasm, not elsewhere classified
0.513 0.487 0.000
K31.2 Hourglass stricture and stenosis of stomach
0.513 0.487 0.000
K31.1 Adult hypertrophic pyloric stenosis
0.513 0.487 0.000
K31.0 Acute dilatation of stomach
0.513 0.487 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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