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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16967767
log Bayes Factor = 16.5612
Chromosome 13   position 106,606,772  (GRCh37) Explore rs16967767 on Ensembl!
Variant rs16967767 is part of Cluster X0033

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter II Neoplasms
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Z51 Other medical care
1.000 0.000 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
1.000 0.000 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
1.000 0.000 0.000
Z51.1 Chemotherapy session for neoplasm
1.000 0.000 0.000
C79 Secondary malignant neoplasm of other sites
0.997 0.003 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.997 0.003 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.996 0.004 0.000
Chapter XX External causes of morbidity and mortality
0.992 0.008 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.986 0.014 0.000
Chapter V Mental and behavioural disorders
0.983 0.017 0.000
M50-M54 Other dorsopathies
0.980 0.020 0.000
M54 Dorsalgia
0.974 0.026 0.000
Chapter I Certain infectious and parasitic diseases
0.974 0.026 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.973 0.027 0.000
Chapter XIV Diseases of the genitourinary system
0.973 0.027 0.000
C79.5 Secondary malignant neoplasm of bone and bone marrow
0.972 0.028 0.000
N20-N23 Urolithiasis
0.972 0.028 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.971 0.029 0.000
Z60 Problems related to social environment
0.969 0.031 0.000
D10-D36 Benign neoplasms
0.967 0.033 0.000
S00-S09 Injuries to the head
0.966 0.034 0.000
Z51.5 Palliative care
0.961 0.039 0.000
B95-B98 Bacterial, viral and other infectious agents
0.960 0.040 0.000
M54.5 Low back pain
0.959 0.041 0.000
N23 Unspecified renal colic
0.959 0.041 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.958 0.042 0.000
Z60.2 Living alone
0.958 0.042 0.000
Chapter VII Diseases of the eye and adnexa
0.948 0.052 0.000
N20 Calculus of kidney and ureter
0.935 0.065 0.000
C15-C26 Malignant neoplasms of digestive organs
0.934 0.066 0.000
Chapter X Diseases of the respiratory system
0.932 0.068 0.000
M54.56 Low back pain (Lumbar region)
0.932 0.068 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.931 0.069 0.000
Z51.3 Blood transfusion without reported diagnosis
0.927 0.073 0.000
C60-C63 Malignant neoplasms of male genital organs
0.925 0.075 0.000
J90-J94 Other diseases of pleura
0.921 0.079 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.919 0.081 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.919 0.081 0.000
D60-D64 Aplastic and other anaemias
0.918 0.082 0.000
F17 Mental and behavioural disorders due to use of tobacco
0.911 0.089 0.000
M65-M68 Disorders of synovium and tendon
0.910 0.090 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.910 0.090 0.000
D17 Benign lipomatous neoplasm
0.908 0.092 0.000
S01 Open wound of head
0.904 0.096 0.000
D24 Benign neoplasm of breast
0.902 0.098 0.000
J90 Pleural effusion, not elsewhere classified
0.901 0.099 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.899 0.101 0.000
F17.1 Harmful use
0.898 0.102 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.893 0.107 0.000
Y43 Primarily systemic agents
0.889 0.111 0.000
D70 Agranulocytosis
0.888 0.112 0.000
Z45 Adjustment and management of implanted device
0.881 0.119 0.000
Z46 Fitting and adjustment of other devices
0.880 0.120 0.000
H25-H28 Disorders of lens
0.880 0.120 0.000
B96.8 Other specified bacterial agents as the cause of diseases classified to other chapters
0.880 0.120 0.000
Chapter XXII Codes for special purposes
0.878 0.122 0.000
N20.0 Calculus of kidney
0.878 0.122 0.000
Y84 Other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.876 0.124 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.871 0.129 0.000
J95-J99 Other diseases of the respiratory system
0.871 0.129 0.000
C61 Malignant neoplasm of prostate
0.871 0.129 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.868 0.132 0.000
C79.3 Secondary malignant neoplasm of brain and cerebral meninges
0.866 0.134 0.000
D64 Other anaemias
0.865 0.135 0.000
M65 Synovitis and tenosynovitis
0.864 0.136 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.859 0.141 0.000
C79.9 Secondary malignant neoplasm, unspecified site
0.858 0.142 0.000
C77.0 Lymph nodes of head, face and neck
0.851 0.149 0.000
C79.2 Secondary malignant neoplasm of skin
0.849 0.151 0.000
M54.9 Dorsalgia, unspecified
0.848 0.152 0.000
M05-M14 Inflammatory polyarthropathies
0.841 0.159 0.000
C77.2 Intra-abdominal lymph nodes
0.840 0.160 0.000
D35 Benign neoplasm of other and unspecified endocrine glands
0.840 0.160 0.000
Y43.3 Other antineoplastic drugs
0.839 0.161 0.000
B95.5 Unspecified streptococcus as the cause of diseases classified to other chapters
0.838 0.162 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.834 0.166 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.832 0.168 0.000
D64.9 Anaemia, unspecified
0.828 0.172 0.000
J98 Other respiratory disorders
0.827 0.173 0.000
H25 Senile cataract
0.826 0.174 0.000
N20.1 Calculus of ureter
0.817 0.183 0.000
M70-M79 Other soft tissue disorders
0.817 0.183 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.817 0.183 0.000
S60-S69 Injuries to the wrist and hand
0.815 0.185 0.000
C18 Malignant neoplasm of colon
0.814 0.186 0.000
Z45.2 Adjustment and management of vascular access device
0.814 0.186 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.814 0.186 0.000
M54.59 Low back pain (Site unspecified)
0.813 0.187 0.000
C77.5 Intrapelvic lymph nodes
0.812 0.188 0.000
Z57 Occupational exposure to risk-factors
0.810 0.190 0.000
S02 Fracture of skull and facial bones
0.807 0.193 0.000
T66-T78 Other and unspecified effects of external causes
0.807 0.193 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.806 0.194 0.000
C79.6 Secondary malignant neoplasm of ovary
0.806 0.194 0.000
C77.1 Intrathoracic lymph nodes
0.806 0.194 0.000
F41 Other anxiety disorders
0.806 0.194 0.000
Z51.0 Radiotherapy session
0.805 0.195 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.800 0.200 0.000
J93 Pneumothorax
0.800 0.200 0.000
H30-H36 Disorders of choroid and retina
0.798 0.202 0.000
M86-M90 Other osteopathies
0.795 0.205 0.000
Z46.6 Fitting and adjustment of urinary device
0.795 0.205 0.000
S80-S89 Injuries to the knee and lower leg
0.794 0.206 0.000
C78.7 Secondary malignant neoplasm of liver
0.794 0.206 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.793 0.207 0.000
C77.9 Lymph node, unspecified
0.793 0.207 0.000
S40-S49 Injuries to the shoulder and upper arm
0.793 0.207 0.000
C80 Malignant neoplasm without specification of site
0.792 0.208 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.791 0.209 0.000
W20-W49 Exposure to inanimate mechanical forces
0.789 0.211 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.789 0.211 0.000
Y84.2 Radiological procedure and radiotherapy
0.788 0.212 0.000
D17.9 Benign lipomatous neoplasm, unspecified
0.787 0.213 0.000
J98.1 Pulmonary collapse
0.787 0.213 0.000
H55-H59 Other disorders of eye and adnexa
0.787 0.213 0.000
H25.1 Senile nuclear cataract
0.786 0.214 0.000
S50-S59 Injuries to the elbow and forearm
0.786 0.214 0.000
N10-N16 Renal tubulo-interstitial diseases
0.785 0.215 0.000
S01.8 Open wound of other parts of head
0.783 0.217 0.000
Chapter VI Diseases of the nervous system
0.780 0.220 0.000
C34 Malignant neoplasm of bronchus and lung
0.779 0.221 0.000
Z52 Donors of organs and tissues
0.779 0.221 0.000
D34 Benign neoplasm of thyroid gland
0.777 0.223 0.000
M40-M43 Deforming dorsopathies
0.775 0.225 0.000
M54.2 Cervicalgia
0.774 0.226 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.770 0.230 0.000
M54.50 Low back pain (Multiple sites in spine)
0.767 0.233 0.000
Y84.8 Other medical procedures
0.766 0.234 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.766 0.234 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.766 0.234 0.000
W00-W19 Falls
0.765 0.235 0.000
N21 Calculus of lower urinary tract
0.765 0.235 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.763 0.236 0.000
M13 Other arthritis
0.763 0.237 0.000
D17.1 Benign lipomatous neoplasm of skin and subcutaneous tissue of trunk
0.762 0.238 0.000
Z92 Personal history of medical treatment
0.762 0.238 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.760 0.240 0.000
D26 Other benign neoplasms of uterus
0.758 0.242 0.000
S09 Other and unspecified injuries of head
0.757 0.243 0.000
Y40 Systemic antibiotics
0.757 0.243 0.000
M54.6 Pain in thoracic spine
0.755 0.245 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.753 0.247 0.000
D10 Benign neoplasm of mouth and pharynx
0.752 0.248 0.000
D14 Benign neoplasm of middle ear and respiratory system
0.751 0.249 0.000
C79.8 Secondary malignant neoplasm of other specified sites
0.750 0.250 0.000
V20-V29 Motorcycle rider injured in transport accident
0.749 0.251 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.749 0.251 0.000
Z51.8 Other specified medical care
0.747 0.253 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.744 0.256 0.000
Y52 Agents primarily affecting the cardiovascular system
0.744 0.256 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.743 0.257 0.000
G90-G99 Other disorders of the nervous system
0.742 0.258 0.000
C20 Malignant neoplasm of rectum
0.741 0.259 0.000
S06 Intracranial injury
0.740 0.260 0.000
A00-A09 Intestinal infectious diseases
0.740 0.260 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.739 0.261 0.000
C16 Malignant neoplasm of stomach
0.737 0.263 0.000
D35.1 Parathyroid gland
0.737 0.263 0.000
C79.7 Secondary malignant neoplasm of adrenal gland
0.733 0.267 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.732 0.267 0.000
S01.3 Open wound of ear
0.732 0.268 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.729 0.271 0.000
D17.5 Benign lipomatous neoplasm of intra-abdominal organs
0.727 0.273 0.000
F99-F99 Unspecified mental disorder
0.727 0.273 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.726 0.274 0.000
D22 Melanocytic naevi
0.725 0.275 0.000
Z53 Persons encountering health services for specifie procedures, not carried out
0.723 0.277 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.723 0.277 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.722 0.277 0.000
Z41 Procedures for purposes other than remedying health state
0.720 0.280 0.000
Z92.6 Personal history of chemotherapy for neoplastic disease
0.719 0.281 0.000
Z51.2 Other chemotherapy
0.717 0.283 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.717 0.283 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.717 0.283 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.717 0.283 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.717 0.283 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z51.9 Medical care, unspecified
0.717 0.283 0.000
Z51.6 Desensitisation to allergens
0.717 0.283 0.000
C51-C58 Malignant neoplasms of female genital organs
0.717 0.283 0.000
C76 Malignant neoplasm of other and ill-defined sites
0.717 0.283 0.000
Z54 Convalescence
0.717 0.283 0.000
Z49 Care involving dialysis
0.717 0.283 0.000
Z44 Fitting and adjustment of external prosthetic device
0.717 0.283 0.000
D33 Benign neoplasm of brain and other parts of central nervous system
0.715 0.285 0.000
C79.4 Secondary malignant neoplasm of other and unspecified parts of nervous system
0.715 0.285 0.000
C79.1 Secondary malignant neoplasm of bladder and other and unspecified urinary organs
0.715 0.285 0.000
C79.0 Secondary malignant neoplasm of kidney and renal pelvis
0.715 0.285 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.715 0.285 0.000
C34.1 Upper lobe, bronchus or lung
0.715 0.285 0.000
M91-M94 Chondropathies
0.714 0.286 0.000
M60-M63 Disorders of muscles
0.714 0.286 0.000
M00-M03 Infectious arthropathies
0.714 0.286 0.000
N00-N08 Glomerular diseases
0.714 0.286 0.000
H10-H13 Disorders of conjunctiva
0.714 0.286 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.714 0.286 0.000
S01.5 Open wound of lip and oral cavity
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X60-X84 Intentional self-harm
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.710 0.290 0.000
M65.96 Synovitis and tenosynovitis, unspecified (Lower leg)
0.710 0.290 0.000
M65.97 Synovitis and tenosynovitis, unspecified (Ankle and foot)
0.709 0.291 0.000
G93 Other disorders of brain
0.709 0.291 0.000
Y84.1 Kidney dialysis
0.708 0.292 0.000
M13.9 Arthritis, unspecified
0.708 0.292 0.000
Z42 Follow-up care involving plastic surgery
0.707 0.293 0.000
Z65 Problems related to other psychosocial circumstances
0.707 0.293 0.000
Z64 Problems related to certain psychosocial circumstances
0.707 0.293 0.000
Z63 Other problems related to primary support group, including family circumstances
0.707 0.293 0.000
Z62 Other problems related to upbringing
0.707 0.293 0.000
Z61 Problems related to negative life events in childhood
0.707 0.293 0.000
Z59 Problems related to housing and economic circumstances
0.707 0.293 0.000
Z58 Problems related to physical environment
0.707 0.293 0.000
Z56 Problems related to employment and unemployment
0.707 0.293 0.000
Z55 Problems related to education and literacy
0.707 0.293 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.706 0.294 0.000
C18.9 Colon, unspecified
0.706 0.294 0.000
D63 Anaemia in chronic diseases classified elsewhere
0.705 0.295 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.705 0.295 0.000
F80-F89 Disorders of psychological development
0.705 0.295 0.000
F70-F79 Mental retardation
0.705 0.295 0.000
F60-F69 Disorders of adult personality and behaviour
0.705 0.295 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.705 0.295 0.000
M53 Other dorsopathies, not elsewhere classified
0.703 0.297 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.702 0.298 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.701 0.299 0.000
S01.0 Open wound of scalp
0.699 0.301 0.000
S00 Superficial injury of head
0.699 0.301 0.000
B96.4 Proteus (mirabilis)(morganii) as the cause of diseases classified to other chapters
0.699 0.301 0.000
M54.8 Other dorsalgia
0.698 0.301 0.000
M54.4 Lumbago with sciatica
0.698 0.301 0.000
M54.1 Radiculopathy
0.698 0.301 0.000
M54.0 Panniculitis affecting regions of neck and back
0.698 0.301 0.000
B99-B99 Other infectious diseases
0.698 0.302 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.698 0.302 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.698 0.302 0.000
B65-B83 Helminthiases
0.698 0.302 0.000
B50-B64 Protozoal diseases
0.698 0.302 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.698 0.302 0.000
B15-B19 Viral hepatitis
0.698 0.302 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.698 0.302 0.000
A80-A89 Viral infections of the central nervous system
0.698 0.302 0.000
A75-A79 Rickettsioses
0.698 0.302 0.000
A70-A74 Other diseases caused by chlamydiae
0.698 0.302 0.000
A65-A69 Other spirochaetal diseases
0.698 0.302 0.000
A20-A28 Certain zoonotic bacterial diseases
0.698 0.302 0.000
A15-A19 Tuberculosis
0.698 0.302 0.000
S90-S99 Injuries to the ankle and foot
0.698 0.302 0.000
D55-D59 Haemolytic anaemias
0.698 0.302 0.000
N22 Calculus of urinary tract in diseases classified elsewhere
0.697 0.303 0.000
C77.8 Lymph nodes of multiple regions
0.696 0.304 0.000
C77.4 Inguinal and lower limb lymph nodes
0.696 0.304 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.696 0.304 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.696 0.304 0.000
S02.4 Fracture of malar and maxillary bones
0.696 0.304 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.695 0.305 0.000
Z60.9 Problem related to social environment, unspecified
0.695 0.305 0.000
Z60.8 Other problems related to social environment
0.695 0.305 0.000
Z60.5 Target of perceived adverse discrimination and persecution
0.695 0.305 0.000
Z60.4 Social exclusion and rejection
0.695 0.305 0.000
Z60.3 Acculturation difficulty
0.695 0.305 0.000
Z60.1 Atypical parenting situation
0.695 0.305 0.000
Z60.0 Problems of adjustment to life-cycle transitions
0.695 0.305 0.000
C15 Malignant neoplasm of oesophagus
0.694 0.306 0.000
S70-S79 Injuries to the hip and thigh
0.694 0.306 0.000
D31 Benign neoplasm of eye and adnexa
0.693 0.307 0.000
D30 Benign neoplasm of urinary organs
0.693 0.307 0.000
D29 Benign neoplasm of male genital organs
0.693 0.307 0.000
D28 Benign neoplasm of other and unspecified female genital organs
0.693 0.307 0.000
D21 Other benign neoplasms of connective and other soft tissue
0.693 0.307 0.000
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum
0.693 0.307 0.000
D19 Benign neoplasm of mesothelial tissue
0.693 0.307 0.000
D16 Benign neoplasm of bone and articular cartilage
0.693 0.307 0.000
D15 Benign neoplasm of other and unspecified intrathoracic organs
0.693 0.307 0.000
Z48 Other surgical follow-up care
0.693 0.307 0.000
J92 Pleural plaque
0.693 0.307 0.000
S08 Traumatic amputation of part of head
0.693 0.307 0.000
S07 Crushing injury of head
0.693 0.307 0.000
S05 Injury of eye and orbit
0.693 0.307 0.000
S04 Injury of cranial nerves
0.693 0.307 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.693 0.307 0.000
N25-N29 Other disorders of kidney and ureter
0.692 0.307 0.000
B98 Other specified infectious agents as the cause of diseases classified to other chapters
0.691 0.308 0.000
D18 Haemangioma and lymphangioma, any site
0.691 0.308 0.000
D17.6 Benign lipomatous neoplasm of spermatic cord
0.691 0.309 0.000
M65.4 Radial styloid tenosynovitis [de Quervain]
0.691 0.309 0.000
D80-D89 Certain disorders involving the immune mechanism
0.690 0.310 0.000
C78.0 Secondary malignant neoplasm of lung
0.690 0.310 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.689 0.310 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.689 0.310 0.000
F30-F39 Mood [affective] disorders
0.689 0.311 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.688 0.312 0.000
M54.55 Low back pain (Thoracolumbar region)
0.688 0.312 0.000
M54.54 Low back pain-Thoracic
0.688 0.312 0.000
M54.53 Low back pain-Cervicothoracic
0.688 0.312 0.000
M54.52 Low back pain-Cervical
0.688 0.312 0.000
M54.51 Low back pain-Occipit-atl-axl
0.688 0.312 0.000
S01.1 Open wound of eyelid and periocular area
0.687 0.313 0.000
Y59 Other and unspecified vaccines and biological substances
0.686 0.313 0.000
Y58 Bacterial vaccines
0.686 0.313 0.000
Y57 Other and unspecified drugs and medicaments
0.686 0.313 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.686 0.313 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.686 0.313 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.686 0.313 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.686 0.313 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.686 0.313 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.686 0.313 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.686 0.313 0.000
Y48 Anaesthetics and therapeutic gases
0.686 0.313 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.686 0.313 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.686 0.313 0.000
Y44 Agents primarily affecting blood constituents
0.686 0.313 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.686 0.313 0.000
N99-N99 Other disorders of the genitourinary system
0.684 0.316 0.000
Z93 Artificial opening status
0.684 0.316 0.000
Chapter VIII Diseases of the ear and mastoid process
0.683 0.317 0.000
F41.9 Anxiety disorder, unspecified
0.683 0.317 0.000
U80 Agent resistant to penicillin and related antibiotics
0.681 0.319 0.000
S20-S29 Injuries to the thorax
0.680 0.319 0.000
D61 Other aplastic anaemias
0.680 0.320 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.680 0.320 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.679 0.321 0.000
M54.3 Sciatica
0.679 0.321 0.000
M45-M49 Spondylopathies
0.679 0.321 0.000
A30-A49 Other bacterial diseases
0.678 0.322 0.000
B35-B49 Mycoses
0.676 0.324 0.000
Z45.1 Adjustment and management of infusion pump
0.675 0.325 0.000
D32 Benign neoplasm of meninges
0.674 0.326 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.672 0.328 0.000
V10-V19 Pedal cyclist injured in transport accident
0.670 0.330 0.000
J93.9 Pneumothorax, unspecified
0.670 0.330 0.000
N20.9 Urinary calculus, unspecified
0.670 0.330 0.000
A04 Other bacterial intestinal infections
0.670 0.330 0.000
T78 Adverse effects, not elsewhere classified
0.670 0.330 0.000
D17.7 Benign lipomatous neoplasm of other sites
0.670 0.330 0.000
C26 Malignant neoplasm of other and ill-defined digestive organs
0.670 0.330 0.000
C24 Malignant neoplasm of other and unspecified parts of biliary tract
0.670 0.330 0.000
C21 Malignant neoplasm of anus and anal canal
0.670 0.330 0.000
C17 Malignant neoplasm of small intestine
0.670 0.330 0.000
C23 Malignant neoplasm of gallbladder
0.670 0.330 0.000
C78.2 Secondary malignant neoplasm of pleura
0.670 0.330 0.000
M65.3 Trigger finger
0.669 0.331 0.000
C18.4 Transverse colon
0.669 0.331 0.000
Z96 Presence of other functional implants
0.669 0.331 0.000
F03 Unspecified dementia
0.668 0.332 0.000
S81 Open wound of lower leg
0.668 0.332 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.667 0.333 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.667 0.333 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.667 0.333 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.667 0.333 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.667 0.333 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.667 0.333 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.667 0.333 0.000
F11 Mental and behavioural disorders due to use of opioids
0.667 0.333 0.000
M79.8 Other specified soft tissue disorders
0.667 0.333 0.000
H53-H54 Visual disturbances and blindness
0.666 0.334 0.000
T93 Sequelae of injuries of lower limb
0.666 0.334 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.664 0.336 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.663 0.337 0.000
C62 Malignant neoplasm of testis
0.663 0.337 0.000
C60 Malignant neoplasm of penis
0.663 0.337 0.000
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck
0.662 0.338 0.000
Z57.5 Occupational exposure to toxic agents in other industries
0.662 0.338 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.660 0.339 0.000
J94 Other pleural conditions
0.660 0.339 0.000
J91 Pleural effusion in conditions classified elsewhere
0.660 0.339 0.000
D76 Certain diseases involving lymphoreticular tissue and reticulohistiocytic system
0.659 0.341 0.000
D74 Methaemoglobinaemia
0.659 0.341 0.000
D72 Other disorders of white blood cells
0.659 0.341 0.000
D77 Other disorders of blood and blood-forming organs in diseases classified elsewhere
0.659 0.341 0.000
D71 Functional disorders of polymorphonuclear neutrophils
0.659 0.341 0.000
H43-H45 Disorders of vitreous body and globe
0.659 0.341 0.000
D60 Acquired pure red cell aplasia [erythroblastopenia]
0.658 0.342 0.000
D62 Acute posthaemorrhagic anaemia
0.658 0.342 0.000
H26 Other cataract
0.657 0.342 0.000
N20.2 Calculus of kidney with calculus of ureter
0.657 0.343 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.657 0.343 0.000
Z86 Personal history of certain other diseases
0.657 0.343 0.000
F41.2 Mixed anxiety and depressive disorder
0.656 0.344 0.000
G93.3 Postviral fatigue syndrome
0.655 0.345 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.655 0.345 0.000
T92 Sequelae of injuries of upper limb
0.655 0.345 0.000
Z53.9 Procedure not carried out, unspecified reason
0.655 0.345 0.000
Z43 Attention to artificial openings
0.654 0.346 0.000
F17.9 Unspecified mental and behavioural disorder
0.653 0.347 0.000
F17.8 Other mental and behavioural disorders
0.653 0.347 0.000
F17.7 Residual and late-onset psychotic disorder
0.653 0.347 0.000
F17.6 Amnesic syndrome
0.653 0.347 0.000
F17.5 Psychotic disorder
0.653 0.347 0.000
F17.4 Withdrawal state with delirium
0.653 0.347 0.000
F17.3 Withdrawal state
0.653 0.347 0.000
F17.0 Acute intoxication
0.653 0.347 0.000
D11 Benign neoplasm of major salivary glands
0.653 0.347 0.000
M68 Disorders of synovium and tendon in diseases classified elsewhere
0.652 0.347 0.000
M66 Spontaneous rupture of synovium and tendon
0.652 0.347 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.652 0.348 0.000
B95.2 Streptococcus, group D, as the cause of diseases classified to other chapters
0.652 0.348 0.000
B95.0 Streptococcus, group A, as the cause of diseases classified to other chapters
0.652 0.348 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.652 0.348 0.000
N92 Excessive, frequent and irregular menstruation
0.652 0.348 0.000
H33 Retinal detachments and breaks
0.652 0.348 0.000
D17.4 Benign lipomatous neoplasm of intrathoracic organs
0.651 0.349 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.651 0.349 0.000
H34 Retinal vascular occlusions
0.650 0.350 0.000
D75 Other diseases of blood and blood-forming organs
0.650 0.350 0.000
J93.1 Other spontaneous pneumothorax
0.650 0.350 0.000
M77 Other enthesopathies
0.650 0.350 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.649 0.351 0.000
M20-M25 Other joint disorders
0.649 0.351 0.000
Z91.1 Personal history of noncompliance with medical treatment and regimen
0.648 0.351 0.000
S01.7 Multiple open wounds of head
0.648 0.352 0.000
S01.4 Open wound of cheek and temporomandibular area
0.648 0.352 0.000
S01.2 Open wound of nose
0.648 0.352 0.000
C22.0 Liver cell carcinoma
0.645 0.355 0.000
B96.7 Clostridium perfringens [C. perfringens] as the cause of diseases classified to other chapters
0.644 0.355 0.000
B96.6 Bacillus fragilis [B. fragilis] as the cause of diseases classified to other chapters
0.644 0.355 0.000
B96.0 Mycoplasma pneumoniae [M. pneumoniae] as the cause of diseases classified to other chapters
0.644 0.355 0.000
F01 Vascular dementia
0.644 0.356 0.000
B96.3 Haemophilus influenzae [H. influenzae] as the cause of diseases classified to other chapters
0.644 0.356 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.643 0.356 0.000
M54.96 Dorsalgia, unspecified (Lumbar region)
0.643 0.357 0.000
C80.0 Malignant neoplasm, primary site unknown, so stated
0.642 0.358 0.000
F17.2 Dependence syndrome
0.642 0.358 0.000
M41 Scoliosis
0.641 0.358 0.000
Y45.1 Salicylates
0.641 0.359 0.000
N92.0 Excessive and frequent menstruation with regular cycle
0.641 0.359 0.000
J98.8 Other specified respiratory disorders
0.641 0.359 0.000
D17.3 Benign lipomatous neoplasm of skin and subcutaneous tissue of other and unspecified sites
0.641 0.359 0.000
C45 Mesothelioma
0.641 0.359 0.000
M54.57 Low back pain (Lumbosacral region)
0.641 0.359 0.000
C78.8 Secondary malignant neoplasm of other and unspecified digestive organs
0.640 0.359 0.000
C78.5 Secondary malignant neoplasm of large intestine and rectum
0.640 0.359 0.000
C78.4 Secondary malignant neoplasm of small intestine
0.640 0.359 0.000
C78.3 Secondary malignant neoplasm of other and unspecified respiratory organs
0.640 0.359 0.000
C78.1 Secondary malignant neoplasm of mediastinum
0.640 0.359 0.000
C92 Myeloid leukaemia
0.640 0.360 0.000
Y45.3 Other nonsteroidal anti-inflammatory drugs [NSAID]
0.640 0.360 0.000
Chapter XI Diseases of the digestive system
0.640 0.360 0.000
C22.9 Liver, unspecified
0.640 0.360 0.000
T39 Poisoning by nonopioid analgesics, antipyretics and antirheumatics
0.639 0.361 0.000
C91 Lymphoid leukaemia
0.639 0.361 0.000
D27 Benign neoplasm of ovary
0.639 0.361 0.000
S64 Injury of nerves at wrist and hand level
0.638 0.362 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.637 0.363 0.000
Y43.9 Primarily systemic agent, unspecified
0.637 0.363 0.000
Y43.8 Other primarily systemic agents, not elsewhere classified
0.637 0.363 0.000
Y43.6 Enzymes, not elsewhere classified
0.637 0.363 0.000
Y43.5 Acidifying and alkalising agents
0.637 0.363 0.000
Y43.4 Immunosuppressive agents
0.637 0.363 0.000
Y43.2 Antineoplastic natural products
0.637 0.363 0.000
Y43.1 Antineoplastic antimetabolites
0.637 0.363 0.000
Y43.0 Antiallergic and antiemetic drugs
0.637 0.363 0.000
S52 Fracture of forearm
0.634 0.366 0.000
N10 Acute tubulo-interstitial nephritis
0.633 0.367 0.000
Q50-Q56 Congenital malformations of genital organs
0.633 0.367 0.000
M80-M85 Disorders of bone density and structure
0.631 0.368 0.000
Z45.9 Adjustment and management of unspecified implanted device
0.631 0.368 0.000
Z45.3 Adjustment and management of implanted hearing device
0.631 0.368 0.000
D35.2 Pituitary gland
0.631 0.369 0.000
Z46.9 Fitting and adjustment of other unspecified device
0.631 0.369 0.000
Z46.8 Fitting and adjustment of other specified devices
0.631 0.369 0.000
Z46.7 Fitting and adjustment of orthopaedic device
0.631 0.369 0.000
Z46.5 Fitting and adjustment of ileostomy and other intestinal appliances
0.631 0.369 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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