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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs16992204
log Bayes Factor = 0.00737991
Chromosome 21   position 36,111,201  (GRCh37) Explore rs16992204 on Ensembl!
Variant rs16992204 is listed in the   GWAS Catalog   ⇪

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
0.015 0.985 0.000
Chapter XI Diseases of the digestive system
0.014 0.985 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.014 0.986 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.013 0.987 0.000
Chapter XXI Factors influencing health status and contact with health services
0.013 0.987 0.000
Chapter XIV Diseases of the genitourinary system
0.012 0.988 0.000
Chapter IX Diseases of the circulatory system
0.012 0.988 0.000
K40-K46 Hernia
0.012 0.988 0.000
Chapter VI Diseases of the nervous system
0.012 0.988 0.000
K29 Gastritis and duodenitis
0.012 0.988 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.012 0.988 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.012 0.988 0.000
Chapter V Mental and behavioural disorders
0.011 0.988 0.000
R50-R69 General symptoms and signs
0.011 0.988 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.011 0.989 0.000
Chapter X Diseases of the respiratory system
0.011 0.989 0.000
K80-K87 Disorders of gallbladder, biliary tract and pancreas
0.011 0.989 0.000
Chapter XXII Codes for special purposes
0.011 0.989 0.000
Chapter XX External causes of morbidity and mortality
0.011 0.989 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.011 0.989 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.011 0.989 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.011 0.989 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.011 0.989 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.011 0.989 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.011 0.989 0.000
Chapter VIII Diseases of the ear and mastoid process
0.011 0.989 0.000
Chapter VII Diseases of the eye and adnexa
0.011 0.989 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.011 0.989 0.000
Chapter II Neoplasms
0.011 0.989 0.000
Chapter I Certain infectious and parasitic diseases
0.011 0.989 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.011 0.989 0.000
K90-K93 Other diseases of the digestive system
0.010 0.989 0.000
K70-K77 Diseases of liver
0.010 0.989 0.000
K65-K67 Diseases of peritoneum
0.010 0.989 0.000
K50-K52 Noninfective enteritis and colitis
0.010 0.989 0.000
K35-K38 Diseases of appendix
0.010 0.989 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.010 0.989 0.000
K55-K64 Other diseases of intestines
0.010 0.989 0.000
R30-R39 Symptoms and signs involving the urinary system
0.010 0.990 0.000
K29.8 Duodenitis
0.010 0.990 0.000
K44 Diaphragmatic hernia
0.010 0.990 0.000
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified
0.010 0.990 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.010 0.990 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.010 0.990 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.010 0.990 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.010 0.990 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.010 0.990 0.000
R47-R49 Symptoms and signs involving speech and voice
0.010 0.990 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.010 0.990 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.010 0.990 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.010 0.990 0.000
K21 Gastro-oesophageal reflux disease
0.010 0.990 0.000
R07 Pain in throat and chest
0.010 0.990 0.000
R19 Other symptoms and signs involving the digestive system and abdomen
0.010 0.990 0.000
N30-N39 Other diseases of urinary system
0.010 0.990 0.000
K29.7 Gastritis, unspecified
0.010 0.990 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.010 0.990 0.000
N80-N98 Noninflammatory disorders of female genital tract
0.010 0.990 0.000
Z86 Personal history of certain other diseases
0.010 0.990 0.000
K31 Other diseases of stomach and duodenum
0.009 0.990 0.000
K28 Gastrojejunal ulcer
0.009 0.990 0.000
K27 Peptic ulcer, site unspecified
0.009 0.990 0.000
K26 Duodenal ulcer
0.009 0.990 0.000
K25 Gastric ulcer
0.009 0.990 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.009 0.990 0.000
K22 Other diseases of oesophagus
0.009 0.990 0.000
K30 Dyspepsia
0.009 0.990 0.000
K20 Oesophagitis
0.009 0.990 0.000
R69 Unknown and unspecified causes of morbidity
0.009 0.990 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.009 0.990 0.000
Z70-Z76 Persons encountering health services in other circumstances
0.009 0.990 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.009 0.990 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.009 0.990 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.009 0.990 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.009 0.990 0.000
K44.9 Diaphragmatic hernia without obstruction or gangrene
0.009 0.991 0.000
N99-N99 Other disorders of the genitourinary system
0.009 0.991 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.009 0.991 0.000
N60-N64 Disorders of breast
0.009 0.991 0.000
N40-N51 Diseases of male genital organs
0.009 0.991 0.000
N25-N29 Other disorders of kidney and ureter
0.009 0.991 0.000
N20-N23 Urolithiasis
0.009 0.991 0.000
N17-N19 Renal failure
0.009 0.991 0.000
N10-N16 Renal tubulo-interstitial diseases
0.009 0.991 0.000
N00-N08 Glomerular diseases
0.009 0.991 0.000
I84 Haemorrhoids
0.009 0.991 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.009 0.991 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.009 0.991 0.000
I60-I69 Cerebrovascular diseases
0.009 0.991 0.000
I30-I52 Other forms of heart disease
0.009 0.991 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.009 0.991 0.000
I20-I25 Ischaemic heart diseases
0.009 0.991 0.000
I05-I09 Chronic rheumatic heart diseases
0.009 0.991 0.000
I00-I02 Acute rheumatic fever
0.009 0.991 0.000
R19.4 Change in bowel habit
0.009 0.991 0.000
K46 Unspecified abdominal hernia
0.009 0.991 0.000
K45 Other abdominal hernia
0.009 0.991 0.000
K43 Ventral hernia
0.009 0.991 0.000
K42 Umbilical hernia
0.009 0.991 0.000
K41 Femoral hernia
0.009 0.991 0.000
K40 Inguinal hernia
0.009 0.991 0.000
K80 Cholelithiasis
0.009 0.991 0.000
G90-G99 Other disorders of the nervous system
0.009 0.991 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.009 0.991 0.000
G70-G73 Diseases of myoneural junction and muscle
0.009 0.991 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.009 0.991 0.000
G40-G47 Episodic and paroxysmal disorders
0.009 0.991 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.009 0.991 0.000
G30-G32 Other degenerative diseases of the nervous system
0.009 0.991 0.000
G20-G26 Extrapyramidal and movement disorders
0.009 0.991 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.009 0.991 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.009 0.991 0.000
Z82 Family history of certain disabilities and chronic diseases leading to disablement
0.009 0.991 0.000
F30-F39 Mood [affective] disorders
0.009 0.991 0.000
K29.9 Gastroduodenitis, unspecified
0.009 0.991 0.000
K29.6 Other gastritis
0.009 0.991 0.000
K29.5 Chronic gastritis, unspecified
0.009 0.991 0.000
K29.4 Chronic atrophic gastritis
0.009 0.991 0.000
K29.3 Chronic superficial gastritis
0.009 0.991 0.000
K29.2 Alcoholic gastritis
0.009 0.991 0.000
K29.1 Other acute gastritis
0.009 0.991 0.000
K29.0 Acute haemorrhagic gastritis
0.009 0.991 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.009 0.991 0.000
R06 Abnormalities of breathing
0.009 0.991 0.000
R04 Haemorrhage from respiratory passages
0.009 0.991 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.009 0.991 0.000
R01 Cardiac murmurs and other cardiac sounds
0.009 0.991 0.000
R00 Abnormalities of heart beat
0.009 0.991 0.000
R05 Cough
0.009 0.991 0.000
R02 Gangrene, not elsewhere classified
0.009 0.991 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.008 0.991 0.000
R10 Abdominal and pelvic pain
0.008 0.991 0.000
R18 Ascites
0.008 0.991 0.000
R17 Unspecified jaundice
0.008 0.991 0.000
R15 Faecal incontinence
0.008 0.991 0.000
R14 Flatulence and related conditions
0.008 0.991 0.000
R13 Dysphagia
0.008 0.991 0.000
R12 Heartburn
0.008 0.991 0.000
R11 Nausea and vomiting
0.008 0.991 0.000
Z86.4 Personal history of psychoactive substance abuse
0.009 0.991 0.000
E70-E90 Metabolic disorders
0.008 0.991 0.000
R07.4 Chest pain, unspecified
0.008 0.991 0.000
E10-E14 Diabetes mellitus
0.008 0.991 0.000
F99-F99 Unspecified mental disorder
0.008 0.991 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.008 0.991 0.000
F80-F89 Disorders of psychological development
0.008 0.991 0.000
F70-F79 Mental retardation
0.008 0.991 0.000
F60-F69 Disorders of adult personality and behaviour
0.008 0.991 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.008 0.991 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.008 0.991 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.008 0.991 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.008 0.991 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.008 0.991 0.000
J40-J47 Chronic lower respiratory diseases
0.008 0.991 0.000
R68 Other general symptoms and signs
0.008 0.991 0.000
R65 Systemic Inflammatory Response Syndrome [SIRS]
0.008 0.991 0.000
R63 Symptoms and signs concerning food and fluid intake
0.008 0.991 0.000
R62 Lack of expected normal physiological development
0.008 0.991 0.000
R61 Hyperhidrosis
0.008 0.991 0.000
R60 Oedema, not elsewhere classified
0.008 0.991 0.000
R59 Enlarged lymph nodes
0.008 0.991 0.000
R57 Shock, not elsewhere classified
0.008 0.991 0.000
R56 Convulsions, not elsewhere classified
0.008 0.991 0.000
R52 Pain, not elsewhere classified
0.008 0.991 0.000
R50 Fever of unknown origin
0.008 0.991 0.000
R64 Cachexia
0.008 0.991 0.000
R58 Haemorrhage, not elsewhere classified
0.008 0.991 0.000
R55 Syncope and collapse
0.008 0.991 0.000
R54 Senility
0.008 0.991 0.000
R53 Malaise and fatigue
0.008 0.991 0.000
R51 Headache
0.008 0.991 0.000
E65-E68 Obesity and other hyperalimentation
0.008 0.991 0.000
E50-E64 Other nutritional deficiencies
0.008 0.991 0.000
E40-E46 Malnutrition
0.008 0.991 0.000
E20-E35 Disorders of other endocrine glands
0.008 0.991 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.008 0.991 0.000
E00-E07 Disorders of thyroid gland
0.008 0.991 0.000
J95-J99 Other diseases of the respiratory system
0.008 0.992 0.000
J90-J94 Other diseases of pleura
0.008 0.992 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.008 0.992 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.008 0.992 0.000
J60-J70 Lung diseases due to external agents
0.008 0.992 0.000
J30-J39 Other diseases of upper respiratory tract
0.008 0.992 0.000
J20-J22 Other acute lower respiratory infections
0.008 0.992 0.000
J09-J18 Influenza and pneumonia
0.008 0.992 0.000
J00-J06 Acute upper respiratory infections
0.008 0.992 0.000
I10-I15 Hypertensive diseases
0.008 0.992 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.008 0.992 0.000
K87 Disorders of gallbladder, biliary tract and pancreas in diseases classified elsewhere
0.008 0.992 0.000
K86 Other diseases of pancreas
0.008 0.992 0.000
K85 Acute pancreatitis
0.008 0.992 0.000
K83 Other diseases of biliary tract
0.008 0.992 0.000
K82 Other diseases of gallbladder
0.008 0.992 0.000
K81 Cholecystitis
0.008 0.992 0.000
B99-B99 Other infectious diseases
0.008 0.992 0.000
B95-B98 Bacterial, viral and other infectious agents
0.008 0.992 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.008 0.992 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.008 0.992 0.000
B65-B83 Helminthiases
0.008 0.992 0.000
B50-B64 Protozoal diseases
0.008 0.992 0.000
B35-B49 Mycoses
0.008 0.992 0.000
B25-B34 Other viral diseases
0.008 0.992 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.008 0.992 0.000
B15-B19 Viral hepatitis
0.008 0.992 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.008 0.992 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.008 0.992 0.000
A80-A89 Viral infections of the central nervous system
0.008 0.992 0.000
A75-A79 Rickettsioses
0.008 0.992 0.000
A70-A74 Other diseases caused by chlamydiae
0.008 0.992 0.000
A65-A69 Other spirochaetal diseases
0.008 0.992 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.008 0.992 0.000
A30-A49 Other bacterial diseases
0.008 0.992 0.000
A20-A28 Certain zoonotic bacterial diseases
0.008 0.992 0.000
A15-A19 Tuberculosis
0.008 0.992 0.000
A00-A09 Intestinal infectious diseases
0.008 0.992 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.008 0.992 0.000
D10-D36 Benign neoplasms
0.008 0.992 0.000
D00-D09 In situ neoplasms
0.008 0.992 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.008 0.992 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.008 0.992 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.008 0.992 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.008 0.992 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.008 0.992 0.000
C64-C68 Malignant neoplasms of urinary tract
0.008 0.992 0.000
C60-C63 Malignant neoplasms of male genital organs
0.008 0.992 0.000
C51-C58 Malignant neoplasms of female genital organs
0.008 0.992 0.000
C50-C50 Malignant neoplasm of breast
0.008 0.992 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.008 0.992 0.000
C43-C44 Melanoma and other malignant neoplasms of skin
0.008 0.992 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.008 0.992 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.008 0.992 0.000
C15-C26 Malignant neoplasms of digestive organs
0.008 0.992 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.008 0.992 0.000
D80-D89 Certain disorders involving the immune mechanism
0.008 0.992 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.008 0.992 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.008 0.992 0.000
D60-D64 Aplastic and other anaemias
0.008 0.992 0.000
D55-D59 Haemolytic anaemias
0.008 0.992 0.000
D50-D53 Nutritional anaemias
0.008 0.992 0.000
H55-H59 Other disorders of eye and adnexa
0.008 0.992 0.000
H53-H54 Visual disturbances and blindness
0.008 0.992 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.008 0.992 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.008 0.992 0.000
H43-H45 Disorders of vitreous body and globe
0.008 0.992 0.000
H40-H42 Glaucoma
0.008 0.992 0.000
H30-H36 Disorders of choroid and retina
0.008 0.992 0.000
H25-H28 Disorders of lens
0.008 0.992 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.008 0.992 0.000
H10-H13 Disorders of conjunctiva
0.008 0.992 0.000
H00-H06 Disorders of eyelid, lacrimal system and orbit
0.008 0.992 0.000
H90-H95 Other disorders of ear
0.008 0.992 0.000
H80-H83 Diseases of inner ear
0.008 0.992 0.000
H65-H75 Diseases of middle ear and mastoid
0.008 0.992 0.000
H60-H62 Diseases of external ear
0.008 0.992 0.000
L80-L99 Other disorders of the skin and subcutaneous tissue
0.008 0.992 0.000
L60-L75 Disorders of skin appendages
0.008 0.992 0.000
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue
0.008 0.992 0.000
L50-L54 Urticaria and erythema
0.008 0.992 0.000
L40-L45 Papulosquamous disorders
0.008 0.992 0.000
L20-L30 Dermatitis and eczema
0.008 0.992 0.000
L10-L14 Bullous disorders
0.008 0.992 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.008 0.992 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.008 0.992 0.000
M91-M94 Chondropathies
0.008 0.992 0.000
M86-M90 Other osteopathies
0.008 0.992 0.000
M80-M85 Disorders of bone density and structure
0.008 0.992 0.000
M70-M79 Other soft tissue disorders
0.008 0.992 0.000
M65-M68 Disorders of synovium and tendon
0.008 0.992 0.000
M60-M63 Disorders of muscles
0.008 0.992 0.000
M50-M54 Other dorsopathies
0.008 0.992 0.000
M45-M49 Spondylopathies
0.008 0.992 0.000
M40-M43 Deforming dorsopathies
0.008 0.992 0.000
M20-M25 Other joint disorders
0.008 0.992 0.000
M05-M14 Inflammatory polyarthropathies
0.008 0.992 0.000
M00-M03 Infectious arthropathies
0.008 0.992 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.008 0.992 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.008 0.992 0.000
T79-T79 Certain early complications of trauma
0.008 0.992 0.000
T66-T78 Other and unspecified effects of external causes
0.008 0.992 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.008 0.992 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.008 0.992 0.000
T33-T35 Frostbite
0.008 0.992 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.008 0.992 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.008 0.992 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.008 0.992 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.008 0.992 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.008 0.992 0.000
T00-T07 Injuries involving multiple body regions
0.008 0.992 0.000
S90-S99 Injuries to the ankle and foot
0.008 0.992 0.000
S80-S89 Injuries to the knee and lower leg
0.008 0.992 0.000
S70-S79 Injuries to the hip and thigh
0.008 0.992 0.000
S60-S69 Injuries to the wrist and hand
0.008 0.992 0.000
S50-S59 Injuries to the elbow and forearm
0.008 0.992 0.000
S40-S49 Injuries to the shoulder and upper arm
0.008 0.992 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.008 0.992 0.000
S20-S29 Injuries to the thorax
0.008 0.992 0.000
S10-S19 Injuries to the neck
0.008 0.992 0.000
S00-S09 Injuries to the head
0.008 0.992 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.008 0.992 0.000
O85-O92 Complications predominantly related to the puerperium
0.008 0.992 0.000
O80-O84 Delivery
0.008 0.992 0.000
O60-O75 Complications of labour and delivery
0.008 0.992 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.008 0.992 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.008 0.992 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.008 0.992 0.000
O00-O08 Pregnancy with abortive outcome
0.008 0.992 0.000
P90-P96 Other disorders originating in the perinatal period
0.008 0.992 0.000
P80-P83 Conditions involving the integument and temperature regulation of fetus and newborn
0.008 0.992 0.000
P75-P78 Digestive system disorders of fetus and newborn
0.008 0.992 0.000
P70-P74 Transitory endocrine and metabolic disorders specific to fetus and newborn
0.008 0.992 0.000
P50-P61 Haemorrhagic and haematological disorders of fetus and newborn
0.008 0.992 0.000
P35-P39 Infections specific to the perinatal period
0.008 0.992 0.000
P20-P29 Respiratory and cardiovascular disorders specific to the perinatal period
0.008 0.992 0.000
P10-P15 Birth trauma
0.008 0.992 0.000
P05-P08 Disorders related to length of gestation and fetal growth
0.008 0.992 0.000
P00-P04 Fetus and newborn affected by maternal factors and by complications of pregnancy, labour and delivery
0.008 0.992 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.008 0.992 0.000
Q80-Q89 Other congenital malformations
0.008 0.992 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.008 0.992 0.000
Q60-Q64 Congenital malformations of the urinary system
0.008 0.992 0.000
Q50-Q56 Congenital malformations of genital organs
0.008 0.992 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.008 0.992 0.000
Q35-Q37 Cleft lip and cleft palate
0.008 0.992 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.008 0.992 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.008 0.992 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.008 0.992 0.000
Q00-Q07 Congenital malformations of the nervous system
0.008 0.992 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.008 0.992 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.008 0.992 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.008 0.992 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.008 0.992 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.008 0.992 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.008 0.992 0.000
Y35-Y36 Legal intervention and operations of war
0.008 0.992 0.000
Y10-Y34 Event of undetermined intent
0.008 0.992 0.000
Y00-Y09 Assault
0.008 0.992 0.000
X85-X99 Assault
0.008 0.992 0.000
X60-X84 Intentional self-harm
0.008 0.992 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.008 0.992 0.000
X50-X57 Overexertion, travel and privation
0.008 0.992 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.008 0.992 0.000
X30-X39 Exposure to forces of nature
0.008 0.992 0.000
X20-X29 Contact with venomous animals and plants
0.008 0.992 0.000
X10-X19 Contact with heat and hot substances
0.008 0.992 0.000
X00-X09 Exposure to smoke, fire and flames
0.008 0.992 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.008 0.992 0.000
W75-W84 Other accidental threats to breathing
0.008 0.992 0.000
W65-W74 Accidental drowning and submersion
0.008 0.992 0.000
W50-W64 Exposure to animate mechanical forces
0.008 0.992 0.000
W20-W49 Exposure to inanimate mechanical forces
0.008 0.992 0.000
W00-W19 Falls
0.008 0.992 0.000
V98-V99 Other and unspecified transport accidents
0.008 0.992 0.000
V95-V97 Air and space transport accidents
0.008 0.992 0.000
V90-V94 Water transport accidents
0.008 0.992 0.000
V80-V89 Other land transport accidents
0.008 0.992 0.000
V70-V79 Bus occupant injured in transport accident
0.008 0.992 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.008 0.992 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.008 0.992 0.000
V40-V49 Car occupant injured in transport accident
0.008 0.992 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.008 0.992 0.000
V20-V29 Motorcycle rider injured in transport accident
0.008 0.992 0.000
V10-V19 Pedal cyclist injured in transport accident
0.008 0.992 0.000
V01-V09 Pedestrian injured in transport accident
0.008 0.992 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.008 0.992 0.000
U00-U49 Provisional assignment of new diseases of uncertain etiology or emergency use
0.008 0.992 0.000
K62 Other diseases of anus and rectum
0.008 0.992 0.000
N39 Other disorders of urinary system
0.008 0.992 0.000
M15-M19 Arthrosis
0.008 0.992 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.008 0.992 0.000
Z98 Other postsurgical states
0.008 0.992 0.000
Z97 Presence of other devices
0.008 0.992 0.000
Z96 Presence of other functional implants
0.008 0.992 0.000
Z95 Presence of cardiac and vascular implants and grafts
0.008 0.992 0.000
Z94 Transplanted organ and tissue status
0.008 0.992 0.000
Z93 Artificial opening status
0.008 0.992 0.000
Z92 Personal history of medical treatment
0.008 0.992 0.000
Z91 Personal history of risk-factors, not elsewhere classified
0.008 0.992 0.000
Z90 Acquired absence of organs, not elsewhere classified
0.008 0.992 0.000
Z89 Acquired absence of limb
0.008 0.992 0.000
Z88 Personal history of allergy to drugs, medicaments and biologocal substances
0.008 0.992 0.000
Z87 Personal history of other diseases and conditions
0.008 0.992 0.000
Z85 Personal history of malignant neoplasm
0.008 0.992 0.000
Z84 Family history of other conditions
0.008 0.992 0.000
Z83 Family history of other specific disorders
0.008 0.992 0.000
Z81 Family history of mental and behavioural disorders
0.008 0.992 0.000
Z80 Family history of malignant neoplasm
0.008 0.992 0.000
R07.3 Other chest pain
0.008 0.992 0.000
I84.6 Residual haemorrhoidal skin tags
0.008 0.992 0.000
G56 Mononeuropathies of upper limb
0.008 0.992 0.000
K14 Diseases of tongue
0.008 0.992 0.000
K13 Other diseases of lip and oral mucosa
0.008 0.992 0.000
K12 Stomatitis and related lesions
0.008 0.992 0.000
K11 Diseases of salivary glands
0.008 0.992 0.000
K10 Other diseases of jaws
0.008 0.992 0.000
K09 Cysts of oral region, not elsewhere classified
0.008 0.992 0.000
K08 Other disorders of teeth and supporting structures
0.008 0.992 0.000
K07 Dentofacial anomalies [including malocclusion]
0.008 0.992 0.000
K06 Other disorders of gingiva and edentulous alveolar ridge
0.008 0.992 0.000
K05 Gingivitis and periodontal diseases
0.008 0.992 0.000
K04 Diseases of pulp and periapical tissues
0.008 0.992 0.000
K03 Other diseases of hard tissues of teeth
0.008 0.992 0.000
K02 Dental caries
0.008 0.992 0.000
K01 Embedded and impacted teeth
0.008 0.992 0.000
K00 Disorders of tooth development and eruption
0.008 0.992 0.000
K38 Other diseases of appendix
0.008 0.992 0.000
K35 Acute appendicitis
0.008 0.992 0.000
K37 Unspecified appendicitis
0.008 0.992 0.000
K36 Other appendicitis
0.008 0.992 0.000
K52 Other non-infective gastro-enteritis and colitis
0.008 0.992 0.000
K51 Ulcerative colitis
0.008 0.992 0.000
K50 Crohn's disease [regional enteritis]
0.008 0.992 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.008 0.992 0.000
K66 Other disorders of peritoneum
0.008 0.992 0.000
K65 Peritonitis
0.008 0.992 0.000
K77 Liver disorders in diseases classified elsewhere
0.008 0.992 0.000
K76 Other diseases of liver
0.008 0.992 0.000
K75 Other inflammatory liver diseases
0.008 0.992 0.000
K74 Fibrosis and cirrhosis of liver
0.008 0.992 0.000
K73 Chronic hepatitis, not elsewhere classified
0.008 0.992 0.000
K72 Hepatic failure, not elsewhere classified
0.008 0.992 0.000
K71 Toxic liver disease
0.008 0.992 0.000
K70 Alcoholic liver disease
0.008 0.992 0.000
K93 Disorders of other digestive organs in diseases classified elsewhere
0.008 0.992 0.000
K92 Other diseases of digestive system
0.008 0.992 0.000
K91 Postprocedural disorders of digestive system, not elsewhere classified
0.008 0.992 0.000
K90 Intestinal malabsorption
0.008 0.992 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.008 0.992 0.000
K63 Other diseases of intestine
0.008 0.992 0.000
K61 Abscess of anal and rectal regions
0.008 0.992 0.000
K60 Fissure and fistula of anal and rectal regions
0.008 0.992 0.000
K59 Other functional intestinal disorders
0.008 0.992 0.000
K58 Irritable bowel syndrome
0.008 0.992 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.008 0.992 0.000
K55 Vascular disorders of intestine
0.008 0.992 0.000
R31 Unspecified haematuria
0.008 0.992 0.000
R39 Other symptoms and signs involving the urinary system
0.008 0.992 0.000
R30 Pain associated with micturition
0.008 0.992 0.000
R36 Urethral discharge
0.008 0.992 0.000
R35 Polyuria
0.008 0.992 0.000
R34 Anuria and oliguria
0.008 0.992 0.000
R33 Retention of urine
0.008 0.992 0.000
R32 Unspecified urinary incontinence
0.008 0.992 0.000
K44.1 Diaphragmatic hernia with gangrene
0.008 0.992 0.000
K44.0 Diaphragmatic hernia with obstruction, without gangrene
0.008 0.992 0.000
I89 Other non-infective disorders of lymphatic vessels and lymph nodes
0.007 0.992 0.000
I88 Nonspecific lymphadenitis
0.007 0.992 0.000
I87 Other disorders of veins
0.007 0.992 0.000
I86 Varicose veins of other sites
0.007 0.992 0.000
I85 Oesophageal varices
0.007 0.992 0.000
I83 Varicose veins of lower extremities
0.007 0.992 0.000
I82 Other venous embolism and thrombosis
0.007 0.992 0.000
I80 Phlebitis and thrombophlebitis
0.007 0.992 0.000
I81 Portal vein thrombosis
0.007 0.992 0.000
N84 Polyp of female genital tract
0.008 0.992 0.000
R23 Other skin changes
0.007 0.992 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.007 0.992 0.000
R20 Disturbances of skin sensation
0.007 0.992 0.000
R21 Rash and other nonspecific skin eruption
0.007 0.992 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.007 0.992 0.000
R27 Other lack of coordination
0.007 0.992 0.000
R26 Abnormalities of gait and mobility
0.007 0.992 0.000
R25 Abnormal involuntary movements
0.007 0.992 0.000
R46 Symptoms and signs involving appearance and behaviour
0.007 0.992 0.000
R45 Symptoms and signs involving emotional state
0.007 0.992 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.007 0.992 0.000
R43 Disturbances of smell and taste
0.007 0.992 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.007 0.992 0.000
R40 Somnolence, stupor and coma
0.007 0.992 0.000
R42 Dizziness and giddiness
0.007 0.992 0.000
R49 Voice disturbances
0.007 0.992 0.000
R48 Dyslexia and other symbolic dysfunctions, not elsewhere classified
0.007 0.992 0.000
R47 Speech disturbances, not elsewhere classified
0.007 0.992 0.000
R79 Other abnormal findings of blood chemistry
0.007 0.992 0.000
R78 Findings of drugs and other substances, not normally found in blood
0.007 0.992 0.000
R77 Other abnormalities of plasma proteins
0.007 0.992 0.000
R76 Other abnormal immunological findings in serum
0.007 0.992 0.000
R74 Abnormal serum enzyme levels
0.007 0.992 0.000
R73 Elevated blood glucose level
0.007 0.992 0.000
R70 Elevated erythrocyte sedimentation rate and abnormality of plasma viscosity
0.007 0.992 0.000
R75 Laboratory evidence of human immunodeficiency virus [HIV]
0.007 0.992 0.000
R72 Abnormality of white blood cells, not elsewhere classified
0.007 0.992 0.000
R71 Abnormality of red blood cells
0.007 0.992 0.000
R82 Other abnormal findings in urine
0.007 0.992 0.000
R81 Glycosuria
0.007 0.992 0.000
R80 Isolated proteinuria
0.007 0.992 0.000
R89 Abnormal findings in specimens from other organs, systems and tissues
0.007 0.992 0.000
R87 Abnormal findings in specimens from female genital organs
0.007 0.992 0.000
R86 Abnormal findings in specimens from male genital organs
0.007 0.992 0.000
R85 Abnormal findings in specimens from digestive organs and abdominal cavity
0.007 0.992 0.000
R84 Abnormal findings in specimens from respiratory organs and thorax
0.007 0.992 0.000
R83 Abnormal findings in cerebrospinal fluid
0.007 0.992 0.000
R94 Abnormal results of function studies
0.007 0.992 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.007 0.992 0.000
R90 Abnormal findings on diagnostic imaging of central nervous system
0.007 0.992 0.000
R92 Abnormal findings on diagnostic imaging of breast
0.007 0.992 0.000
R91 Abnormal findings on diagnostic imaging of lung
0.007 0.992 0.000
R96 Other sudden death, cause unknown
0.007 0.992 0.000
R95 Sudden infant death syndrome
0.007 0.992 0.000
R99 Other ill-defined and unspecified causes of mortality
0.007 0.992 0.000
R98 Unattended death
0.007 0.992 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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