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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17050863
log Bayes Factor = 17.5891
Chromosome 4   position 131,083,338  (GRCh37) Explore rs17050863 on Ensembl!
Variant rs17050863 is part of Cluster X0192

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XXI Factors influencing health status and contact with health services
1.000 0.000 0.000
Chapter X Diseases of the respiratory system
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
1.000 0.000 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.998 0.002 0.000
Chapter IV Endocrine, nutritional and metabolic diseases
0.996 0.004 0.000
Chapter VI Diseases of the nervous system
0.995 0.005 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.994 0.006 0.000
Chapter IX Diseases of the circulatory system
0.991 0.009 0.000
Z50 Care involving use of rehabilitation procedures
0.990 0.010 0.000
Chapter V Mental and behavioural disorders
0.989 0.011 0.000
M70-M79 Other soft tissue disorders
0.987 0.013 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.981 0.019 0.000
M79 Other soft tissue disorders, not elsewhere classified
0.976 0.024 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.976 0.024 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.976 0.024 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.972 0.028 0.000
G40-G47 Episodic and paroxysmal disorders
0.969 0.031 0.000
M50-M54 Other dorsopathies
0.969 0.031 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.959 0.041 0.000
M79.6 Pain in limb
0.956 0.044 0.000
G47 Sleep disorders
0.956 0.044 0.000
M54 Dorsalgia
0.955 0.045 0.000
Z50.1 Other physical therapy
0.955 0.045 0.000
J95-J99 Other diseases of the respiratory system
0.953 0.047 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.950 0.050 0.000
Chapter XIV Diseases of the genitourinary system
0.945 0.055 0.000
E10-E14 Diabetes mellitus
0.944 0.056 0.000
I10-I15 Hypertensive diseases
0.942 0.058 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.937 0.063 0.000
J90-J94 Other diseases of pleura
0.934 0.066 0.000
Chapter VIII Diseases of the ear and mastoid process
0.933 0.067 0.000
M54.5 Low back pain
0.931 0.069 0.000
Chapter I Certain infectious and parasitic diseases
0.928 0.072 0.000
I73 Other peripheral vascular diseases
0.928 0.072 0.000
E70-E90 Metabolic disorders
0.926 0.074 0.000
N17-N19 Renal failure
0.926 0.074 0.000
E65-E68 Obesity and other hyperalimentation
0.922 0.078 0.000
G47.3 Sleep apnoea
0.921 0.079 0.000
M05-M14 Inflammatory polyarthropathies
0.920 0.080 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.919 0.081 0.000
F30-F39 Mood [affective] disorders
0.918 0.082 0.000
Z50.7 Occupational therapy and vocational rehabilitation, not elsewhere classified
0.915 0.085 0.000
F41 Other anxiety disorders
0.912 0.088 0.000
G90-G99 Other disorders of the nervous system
0.910 0.090 0.000
J98 Other respiratory disorders
0.910 0.090 0.000
I12 Hypertensive renal disease
0.906 0.094 0.000
J30-J39 Other diseases of upper respiratory tract
0.901 0.099 0.000
Chapter XX External causes of morbidity and mortality
0.896 0.104 0.000
I73.0 Raynaud's syndrome
0.894 0.106 0.000
M45-M49 Spondylopathies
0.892 0.108 0.000
M79.66 Pain in limb (Lower leg)
0.891 0.109 0.000
J80-J84 Other respiratory diseases principally affecting the interstitium
0.887 0.113 0.000
G47.9 Sleep disorder, unspecified
0.883 0.117 0.000
N18 Chronic renal failure
0.882 0.118 0.000
J40-J47 Chronic lower respiratory diseases
0.880 0.120 0.000
J98.1 Pulmonary collapse
0.878 0.122 0.000
B95-B98 Bacterial, viral and other infectious agents
0.877 0.123 0.000
J90 Pleural effusion, not elsewhere classified
0.877 0.123 0.000
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances
0.875 0.125 0.000
S00-S09 Injuries to the head
0.872 0.128 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.871 0.129 0.000
E66 Obesity
0.870 0.130 0.000
I12.0 Hypertensive renal disease with renal failure
0.868 0.132 0.000
E11 Non-insulin-dependent diabetes mellitus
0.868 0.132 0.000
M79.65 Pain in limb (Pelvic region and thigh)
0.867 0.133 0.000
I60-I69 Cerebrovascular diseases
0.866 0.134 0.000
J33 Nasal polyp
0.860 0.140 0.000
F41.9 Anxiety disorder, unspecified
0.853 0.147 0.000
M54.57 Low back pain (Lumbosacral region)
0.851 0.149 0.000
Z00 General examination and investigation of persons without complaint or reported diagnosis
0.849 0.151 0.000
Z50.5 Speech therapy
0.849 0.151 0.000
Z02 Examination and encounter for administrative purposes
0.848 0.152 0.000
Z09 Follow-up examination after treatment for conditions other than malignant neoplasms
0.845 0.155 0.000
H90-H95 Other disorders of ear
0.845 0.155 0.000
Z49 Care involving dialysis
0.843 0.157 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.842 0.158 0.000
M80-M85 Disorders of bone density and structure
0.840 0.160 0.000
E86 Volume depletion
0.836 0.164 0.000
E87 Other disorders of fluid, electrolyte and acid-base balance
0.834 0.166 0.000
I95-I99 Other and unspecified disorders of the circulatory system
0.833 0.167 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.833 0.167 0.000
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status
0.831 0.169 0.000
F40 Phobic anxiety disorders
0.830 0.170 0.000
E15-E16 Other disorders of glucose regulation and pancreatic internal secretion
0.828 0.171 0.000
F32 Depressive episode
0.828 0.172 0.000
M54.56 Low back pain (Lumbar region)
0.828 0.172 0.000
Z03 Medical observation and evaluation for suspected diseases and conditions
0.827 0.173 0.000
N17 Acute renal failure
0.823 0.177 0.000
H65-H75 Diseases of middle ear and mastoid
0.821 0.179 0.000
J60-J70 Lung diseases due to external agents
0.821 0.179 0.000
G93 Other disorders of brain
0.820 0.180 0.000
N20-N23 Urolithiasis
0.820 0.180 0.000
M54.9 Dorsalgia, unspecified
0.817 0.183 0.000
S50-S59 Injuries to the elbow and forearm
0.817 0.183 0.000
Z43 Attention to artificial openings
0.816 0.184 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.815 0.185 0.000
M79.2 Neuralgia and neuritis, unspecified
0.811 0.189 0.000
J09-J18 Influenza and pneumonia
0.808 0.192 0.000
N18.9 Chronic renal failure, unspecified
0.806 0.194 0.000
Z48 Other surgical follow-up care
0.806 0.194 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.804 0.196 0.000
M77 Other enthesopathies
0.803 0.197 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.803 0.197 0.000
N60-N64 Disorders of breast
0.802 0.198 0.000
E66.9 Obesity, unspecified
0.802 0.198 0.000
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions
0.800 0.200 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.798 0.202 0.000
Z99 Dependence on enabling machines and devices, not elsewhere classified
0.798 0.202 0.000
D80-D89 Certain disorders involving the immune mechanism
0.797 0.203 0.000
T85 Complications of other internal prosthetic devices, implants and grafts
0.797 0.203 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.796 0.203 0.000
E11.9 Without complications
0.795 0.205 0.000
Z51 Other medical care
0.793 0.207 0.000
I71 Aortic aneurysm and dissection
0.791 0.209 0.000
Z50.9 Care involving use of rehabilitation procedure, unspecified
0.790 0.210 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.788 0.211 0.000
M45 Ankylosing spondylitis
0.788 0.212 0.000
I65 Occlusion and stenosis of precerebral arteries, not resulting in cerebral infarction
0.787 0.213 0.000
Z60 Problems related to social environment
0.787 0.213 0.000
E20-E35 Disorders of other endocrine glands
0.785 0.215 0.000
S80-S89 Injuries to the knee and lower leg
0.785 0.215 0.000
Z50.8 Care involving use of rehabilitation procedures
0.784 0.215 0.000
J44 Other chronic obstructive pulmonary disease
0.784 0.216 0.000
B35-B49 Mycoses
0.784 0.216 0.000
I77 Other disorders of arteries and arterioles
0.783 0.217 0.000
N18.5 Chronic kidney disease, stage 5
0.783 0.217 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.780 0.220 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
Chapter XII Diseases of the skin and subcutaneous tissue
0.779 0.221 0.000
Z52 Donors of organs and tissues
0.779 0.221 0.000
N25-N29 Other disorders of kidney and ureter
0.778 0.222 0.000
I72 Other aneurysm
0.778 0.222 0.000
M54.59 Low back pain (Site unspecified)
0.777 0.223 0.000
M40-M43 Deforming dorsopathies
0.777 0.223 0.000
Chapter XI Diseases of the digestive system
0.777 0.223 0.000
M05 Seropositive rheumatoid arthritis
0.776 0.224 0.000
E87.6 Hypokalaemia
0.774 0.226 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.774 0.226 0.000
T86 Failure and rejection of transplanted organs and tissues
0.773 0.227 0.000
J84 Other interstitial pulmonary diseases
0.772 0.228 0.000
M60-M63 Disorders of muscles
0.770 0.230 0.000
Chapter XXII Codes for special purposes
0.770 0.230 0.000
S70-S79 Injuries to the hip and thigh
0.769 0.231 0.000
M79.69 Pain in limb (Site unspecified)
0.766 0.234 0.000
E14 Unspecified diabetes mellitus
0.766 0.234 0.000
M10 Gout
0.764 0.236 0.000
G45 Transient cerebral ischaemic attacks and related syndromes
0.764 0.236 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.763 0.237 0.000
N10-N16 Renal tubulo-interstitial diseases
0.762 0.238 0.000
G20-G26 Extrapyramidal and movement disorders
0.761 0.238 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.761 0.239 0.000
I20-I25 Ischaemic heart diseases
0.760 0.240 0.000
J33.9 Nasal polyp, unspecified
0.760 0.240 0.000
K00-K14 Diseases of oral cavity, salivary glands and jaws
0.760 0.240 0.000
F33 Recurrent depressive disorder
0.759 0.241 0.000
O60-O75 Complications of labour and delivery
0.758 0.242 0.000
S00 Superficial injury of head
0.757 0.243 0.000
Z02.8 Other examinations for administrative purposes
0.757 0.243 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.756 0.244 0.000
B96 Other bacterial agents as the cause of diseases classified to other chapters
0.755 0.245 0.000
Z13 Special screening examination for other diseases and disorders
0.755 0.245 0.000
J00-J06 Acute upper respiratory infections
0.753 0.247 0.000
J47 Bronchiectasis
0.752 0.248 0.000
M79.5 Residual foreign body in soft tissue
0.750 0.250 0.000
F32.9 Depressive episode, unspecified
0.750 0.250 0.000
J92 Pleural plaque
0.750 0.250 0.000
G30-G32 Other degenerative diseases of the nervous system
0.749 0.251 0.000
N20 Calculus of kidney and ureter
0.749 0.251 0.000
N17.9 Acute renal failure, unspecified
0.749 0.251 0.000
H91 Other hearing loss
0.748 0.252 0.000
M06 Other rheumatoid arthritis
0.746 0.254 0.000
Z03.9 Observation for suspected disease or condition, unspecified
0.745 0.255 0.000
M54.1 Radiculopathy
0.744 0.256 0.000
J95 Postprocedural respiratory disorders, not elsewhere classified
0.744 0.256 0.000
J33.0 Polyp of nasal cavity
0.743 0.257 0.000
Z51.5 Palliative care
0.743 0.257 0.000
M79.0 Rheumatism, unspecified
0.741 0.259 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.741 0.259 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.740 0.260 0.000
Z98 Other postsurgical states
0.740 0.260 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.740 0.260 0.000
M79.60 Pain in limb (Multiple sites)
0.739 0.261 0.000
F40.2 Specific (isolated) phobias
0.737 0.263 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.736 0.264 0.000
M79.7 Fibromyalgia
0.736 0.264 0.000
Z49.1 Extracorporeal dialysis
0.735 0.265 0.000
L00-L08 Infections of the skin and subcutaneous tissue
0.735 0.265 0.000
E66.8 Other obesity
0.733 0.267 0.000
E83 Disorders of mineral metabolism
0.733 0.267 0.000
Z87 Personal history of other diseases and conditions
0.732 0.268 0.000
J38 Diseases of vocal cords and larynx, not elsewhere classified
0.731 0.269 0.000
I12.9 Hypertensive renal disease without renal failure
0.731 0.269 0.000
I65.2 Occlusion and stenosis of carotid artery
0.731 0.269 0.000
N00-N08 Glomerular diseases
0.730 0.270 0.000
Z09.9 Follow-up examination after unspecified treatment for other conditions
0.729 0.271 0.000
E88 Other metabolic disorders
0.729 0.271 0.000
M54.3 Sciatica
0.728 0.272 0.000
Z94 Transplanted organ and tissue status
0.725 0.275 0.000
Z60.2 Living alone
0.724 0.276 0.000
M86-M90 Other osteopathies
0.724 0.276 0.000
E13 Other specified diabetes mellitus
0.724 0.276 0.000
Z87.1 Personal history of diseases of the digestive system
0.724 0.276 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.723 0.277 0.000
F41.0 Panic disorder [episodic paroxysmal anxiety]
0.722 0.278 0.000
J85-J86 Suppurative and necrotic conditions of lower respiratory tract
0.721 0.279 0.000
I95 Hypotension
0.720 0.280 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.720 0.280 0.000
G62 Other polyneuropathies
0.720 0.280 0.000
Z93 Artificial opening status
0.719 0.281 0.000
Z51.3 Blood transfusion without reported diagnosis
0.718 0.282 0.000
J94 Other pleural conditions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
Z00.0 General medical examination
0.717 0.283 0.000
M91-M94 Chondropathies
0.717 0.283 0.000
M00-M03 Infectious arthropathies
0.717 0.283 0.000
Z09.0 Follow-up examination after surgery for other conditions
0.716 0.284 0.000
K70-K77 Diseases of liver
0.716 0.284 0.000
J98.0 Diseases of bronchus, not elsewhere classified
0.716 0.284 0.000
Z40 Prophylactic surgery
0.716 0.284 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.716 0.284 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.716 0.284 0.000
T79-T79 Certain early complications of trauma
0.715 0.285 0.000
T33-T35 Frostbite
0.715 0.285 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.715 0.285 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.715 0.285 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.715 0.285 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.715 0.285 0.000
T00-T07 Injuries involving multiple body regions
0.715 0.285 0.000
S10-S19 Injuries to the neck
0.715 0.285 0.000
G95 Other diseases of spinal cord
0.715 0.285 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.715 0.285 0.000
E40-E46 Malnutrition
0.714 0.286 0.000
M45.X9 Ankylosing spondylitis (Site unspecified)
0.714 0.286 0.000
G70-G73 Diseases of myoneural junction and muscle
0.713 0.287 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.713 0.287 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.713 0.287 0.000
Z54 Convalescence
0.713 0.287 0.000
Z44 Fitting and adjustment of external prosthetic device
0.713 0.287 0.000
J81 Pulmonary oedema
0.713 0.287 0.000
I70 Atherosclerosis
0.712 0.288 0.000
J33.8 Other polyp of sinus
0.712 0.288 0.000
N19 Unspecified renal failure
0.711 0.288 0.000
M54.99 Dorsalgia, unspecified (Site unspecified)
0.711 0.289 0.000
I00-I02 Acute rheumatic fever
0.711 0.289 0.000
I64 Stroke, not specified as haemorrhage or infarction
0.711 0.289 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.710 0.290 0.000
Z50.6 Orthoptic training
0.710 0.290 0.000
Z50.4 Psychotherapy, not elsewhere classified
0.710 0.290 0.000
Z50.3 Drug rehabilitation
0.710 0.290 0.000
Z50.2 Alcohol rehabilitation
0.710 0.290 0.000
S20-S29 Injuries to the thorax
0.710 0.290 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.709 0.291 0.000
F99-F99 Unspecified mental disorder
0.709 0.291 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.709 0.291 0.000
F80-F89 Disorders of psychological development
0.709 0.291 0.000
F70-F79 Mental retardation
0.709 0.291 0.000
F60-F69 Disorders of adult personality and behaviour
0.709 0.291 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.709 0.291 0.000
F41.2 Mixed anxiety and depressive disorder
0.709 0.291 0.000
E16 Other disorders of pancreatic internal secretion
0.709 0.291 0.000
I74 Arterial embolism and thrombosis
0.708 0.292 0.000
N99-N99 Other disorders of the genitourinary system
0.708 0.292 0.000
M76 Enthesopathies of lower limb, excluding foot
0.707 0.293 0.000
M73 Soft tissue disorders in diseases classified elsewhere
0.707 0.293 0.000
M71 Other bursopathies
0.707 0.293 0.000
M70 Soft tissue disorders related to use, overuse and pressure
0.707 0.293 0.000
Z04 Examination and observation for other reasons
0.707 0.293 0.000
E10 Insulin-dependent diabetes mellitus
0.707 0.293 0.000
F45 Somatoform disorders
0.705 0.295 0.000
Z30-Z39 Persons encountering health services in circumstances related to reproduction
0.704 0.296 0.000
J44.9 Chronic obstructive pulmonary disease, unspecified
0.703 0.297 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.703 0.297 0.000
T87 Complications peculiar to reattachment and amputation
0.703 0.297 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.703 0.297 0.000
O70 Perineal laceration during delivery
0.701 0.299 0.000
Z13.9 Special screening examination, unspecified
0.701 0.299 0.000
Z01 Other special examinations and investigations of persons without complaint or reported diagnosis
0.701 0.299 0.000
A80-A89 Viral infections of the central nervous system
0.701 0.299 0.000
J61 Pneumoconiosis due to asbestos and other mineral fibres
0.701 0.299 0.000
G93.3 Postviral fatigue syndrome
0.701 0.299 0.000
Z99.2 Dependence on renal dialysis
0.700 0.300 0.000
M79.9 Soft tissue disorder, unspecified
0.700 0.300 0.000
M79.4 Hypertrophy of (infrapatellar) fat pad
0.700 0.300 0.000
M79.3 Panniculitis, unspecified
0.700 0.300 0.000
M79.1 Myalgia
0.700 0.300 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.700 0.300 0.000
Z11 Special screening examination for infectious and parasitic diseases
0.700 0.300 0.000
Z10 Routine general health check-up of defined subpopulation
0.700 0.300 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.700 0.300 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.700 0.300 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.700 0.300 0.000
T82.3 Mechanical complication of other vascular grafts
0.700 0.300 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.700 0.300 0.000
T82.1 Mechanical complication of cardiac electronic device
0.700 0.300 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.700 0.300 0.000
M46 Other inflammatory spondylopathies
0.699 0.301 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.699 0.301 0.000
D50-D53 Nutritional anaemias
0.699 0.301 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.697 0.303 0.000
D86 Sarcoidosis
0.696 0.303 0.000
R30-R39 Symptoms and signs involving the urinary system
0.696 0.304 0.000
M54.4 Lumbago with sciatica
0.696 0.304 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.696 0.304 0.000
B97 Viral agents as the cause of diseases classified to other chapters
0.696 0.304 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.695 0.305 0.000
G41 Status epilepticus
0.695 0.305 0.000
M53 Other dorsopathies, not elsewhere classified
0.694 0.305 0.000
L03 Cellulitis
0.694 0.306 0.000
M79.29 Neuralgia and neuritis, unspecified (Site unspecified)
0.693 0.307 0.000
T66-T78 Other and unspecified effects of external causes
0.693 0.307 0.000
E50-E64 Other nutritional deficiencies
0.693 0.307 0.000
Z99.3 Dependence on wheelchair
0.692 0.308 0.000
M79.8 Other specified soft tissue disorders
0.692 0.308 0.000
Z45 Adjustment and management of implanted device
0.691 0.309 0.000
J31 Chronic rhinitis, nasopharyngitis and pharyngitis
0.691 0.309 0.000
Z43.2 Attention to ileostomy
0.691 0.309 0.000
H90 Conductive and sensorineural hearing loss
0.690 0.310 0.000
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure
0.690 0.310 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.690 0.310 0.000
F43 Reaction to severe stress, and adjustment disorders
0.689 0.310 0.000
N20.1 Calculus of ureter
0.689 0.311 0.000
F48 Other neurotic disorders
0.688 0.312 0.000
F44 Dissociative [conversion] disorders
0.688 0.312 0.000
F42 Obsessive-compulsive disorder
0.688 0.312 0.000
H66 Suppurative and unspecified otitis media
0.687 0.313 0.000
M75 Shoulder lesions
0.686 0.314 0.000
M79.68 Pain in limb (Other)
0.685 0.314 0.000
M79.64 Pain in limb (Hand)
0.685 0.314 0.000
M79.63 Pain in limb (Forearm)
0.685 0.314 0.000
M79.61 Pain in limb (Shoulder region)
0.685 0.314 0.000
G47.8 Other sleep disorders
0.685 0.315 0.000
G47.4 Narcolepsy and cataplexy
0.685 0.315 0.000
G47.2 Disorders of the sleep-wake schedule
0.685 0.315 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.685 0.315 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.685 0.315 0.000
M54.8 Other dorsalgia
0.685 0.315 0.000
M54.6 Pain in thoracic spine
0.685 0.315 0.000
M54.0 Panniculitis affecting regions of neck and back
0.685 0.315 0.000
N18.0 End-stage renal disease
0.685 0.315 0.000
Z00.5 Examination of potential donor of organ and tissue
0.684 0.316 0.000
I05-I09 Chronic rheumatic heart diseases
0.684 0.316 0.000
J84.1 Other interstitial pulmonary diseases with fibrosis
0.684 0.316 0.000
J99 Respiratory disorders in diseases classified elsewhere
0.683 0.317 0.000
J96 Respiratory failure, not elsewhere classified
0.683 0.317 0.000
D68 Other coagulation defects
0.683 0.317 0.000
G82 Paraplegia and tetraplegia
0.682 0.317 0.000
G44 Other headache syndromes
0.681 0.319 0.000
I73.9 Peripheral vascular disease, unspecified
0.681 0.319 0.000
M47 Spondylosis
0.681 0.319 0.000
B37 Candidiasis
0.680 0.320 0.000
A30-A49 Other bacterial diseases
0.680 0.320 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.680 0.320 0.000
F31 Bipolar affective disorder
0.679 0.321 0.000
H91.9 Hearing loss, unspecified
0.679 0.321 0.000
S40-S49 Injuries to the shoulder and upper arm
0.679 0.321 0.000
S32 Fracture of lumbar spine and pelvis
0.679 0.321 0.000
I78 Diseases of capillaries
0.678 0.322 0.000
J20-J22 Other acute lower respiratory infections
0.678 0.322 0.000
E12 Malnutrition-related diabetes mellitus
0.677 0.323 0.000
H71 Cholesteatoma of middle ear
0.677 0.323 0.000
I10 Essential (primary) hypertension
0.677 0.323 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.676 0.324 0.000
I15 Secondary hypertension
0.675 0.325 0.000
I13 Hypertensive heart and renal disease
0.675 0.325 0.000
I11 Hypertensive heart disease
0.675 0.325 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.675 0.325 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.674 0.326 0.000
M05.9 Seropositive rheumatoid arthritis, unspecified
0.673 0.327 0.000
D55-D59 Haemolytic anaemias
0.672 0.328 0.000
Z48.8 Other specified surgical follow-up care
0.672 0.328 0.000
S01 Open wound of head
0.671 0.328 0.000
J91 Pleural effusion in conditions classified elsewhere
0.670 0.330 0.000
S06 Intracranial injury
0.669 0.331 0.000
L03.1 Cellulitis of other parts of limb
0.669 0.331 0.000
N70-N77 Inflammatory diseases of female pelvic organs
0.669 0.331 0.000
H60-H62 Diseases of external ear
0.668 0.332 0.000
N18.2 Chronic kidney disease, stage 2
0.668 0.332 0.000
M54.55 Low back pain (Thoracolumbar region)
0.667 0.333 0.000
M54.54 Low back pain-Thoracic
0.667 0.333 0.000
M54.53 Low back pain-Cervicothoracic
0.667 0.333 0.000
M54.52 Low back pain-Cervical
0.667 0.333 0.000
M54.51 Low back pain-Occipit-atl-axl
0.667 0.333 0.000
M54.50 Low back pain (Multiple sites in spine)
0.667 0.333 0.000
I77.9 Disorder of arteries and arterioles, unspecified
0.667 0.333 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.667 0.333 0.000
E11.3 With ophthalmic complications
0.667 0.333 0.000
K12 Stomatitis and related lesions
0.666 0.334 0.000
M13 Other arthritis
0.665 0.335 0.000
B99-B99 Other infectious diseases
0.665 0.335 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.665 0.335 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.665 0.335 0.000
B65-B83 Helminthiases
0.665 0.335 0.000
B50-B64 Protozoal diseases
0.665 0.335 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.665 0.335 0.000
B15-B19 Viral hepatitis
0.665 0.335 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.665 0.335 0.000
A75-A79 Rickettsioses
0.665 0.335 0.000
A70-A74 Other diseases caused by chlamydiae
0.665 0.335 0.000
A65-A69 Other spirochaetal diseases
0.665 0.335 0.000
A20-A28 Certain zoonotic bacterial diseases
0.665 0.335 0.000
A15-A19 Tuberculosis
0.665 0.335 0.000
I73.8 Other specified peripheral vascular diseases
0.665 0.335 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.665 0.335 0.000
E85 Amyloidosis
0.664 0.336 0.000
E84 Cystic fibrosis
0.664 0.336 0.000
E79 Disorders of purine and pyrimidine metabolism
0.664 0.336 0.000
E77 Disorders of glycoprotein metabolism
0.664 0.336 0.000
E76 Disorders of glycosaminoglycan metabolism
0.664 0.336 0.000
E75 Disorders of sphingolipid metabolism and other lipid storage disorders
0.664 0.336 0.000
E74 Other disorders of carbohydrate metabolism
0.664 0.336 0.000
E73 Lactose intolerance
0.664 0.336 0.000
E72 Other disorders of amino-acid metabolism
0.664 0.336 0.000
E71 Disorders of branched-chain amino-acid metabolism and fatty-acid metabolism
0.664 0.336 0.000
E70 Disorders of aromatic amino-acid metabolism
0.664 0.336 0.000
E90 Nutritional and metabolic disorders in diseases classified elsewhere
0.664 0.336 0.000
W20-W49 Exposure to inanimate mechanical forces
0.663 0.336 0.000
M79.62 Pain in limb (Upper arm)
0.663 0.337 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.661 0.338 0.000
E67 Other hyperalimentation
0.661 0.339 0.000
E68 Sequelae of hyperalimentation
0.661 0.339 0.000
E65 Localised adiposity
0.661 0.339 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.661 0.339 0.000
S02 Fracture of skull and facial bones
0.661 0.339 0.000
Z50.0 Cardiac rehabilitation
0.660 0.340 0.000
B96.5 Pseudomonas (aeruginosa)(mallei)(pseudomallei) as the cause of diseases classified to other chapters
0.659 0.341 0.000
M14 Arthropathies in other diseases classified elsewhere
0.659 0.341 0.000
M12 Other specific arthropathies
0.659 0.341 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.659 0.341 0.000
M08 Juvenile arthritis
0.659 0.341 0.000
M07 Psoriatic and enteropathic arthropathies
0.659 0.341 0.000
N64 Other disorders of breast
0.658 0.341 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.658 0.342 0.000
F38 Other mood [affective] disorders
0.658 0.342 0.000
F34 Persistent mood [affective] disorders
0.658 0.342 0.000
F30 Manic episode
0.658 0.342 0.000
F39 Unspecified mood [affective] disorder
0.658 0.342 0.000
J18 Pneumonia, organism unspecified
0.658 0.342 0.000
K08 Other disorders of teeth and supporting structures
0.657 0.343 0.000
S51 Open wound of forearm
0.657 0.343 0.000
O70.0 First degree perineal laceration during delivery
0.656 0.344 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.656 0.344 0.000
B95.1 Streptococcus, group B, as the cause of diseases classified to other chapters
0.655 0.345 0.000
T85.8 Other complications of internal prosthetic devices, implants and grafts, not elsewhere classified
0.655 0.345 0.000
G91 Hydrocephalus
0.655 0.345 0.000
G93.4 Encephalopathy, unspecified
0.655 0.345 0.000
M79.67 Pain in limb (Ankle and foot)
0.655 0.345 0.000
F41.8 Other specified anxiety disorders
0.654 0.346 0.000
F41.3 Other mixed anxiety disorders
0.654 0.346 0.000
F41.1 Generalised anxiety disorder
0.654 0.346 0.000
R10 Abdominal and pelvic pain
0.654 0.346 0.000
M11 Other crystal arthropathies
0.654 0.346 0.000
E14.3 With ophthalmic complications
0.653 0.347 0.000
M10.9 Gout, unspecified
0.653 0.347 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.653 0.347 0.000
G96 Other disorders of central nervous system
0.653 0.347 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.653 0.347 0.000
G90 Disorders of autonomic nervous system
0.653 0.347 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.653 0.347 0.000
G92 Toxic encephalopathy
0.653 0.347 0.000
J98.9 Respiratory disorder, unspecified
0.652 0.347 0.000
J98.8 Other specified respiratory disorders
0.652 0.347 0.000
J98.6 Disorders of diaphragm
0.652 0.347 0.000
J98.5 Diseases of mediastinum, not elsewhere classified
0.652 0.347 0.000
J98.3 Compensatory emphysema
0.652 0.347 0.000
J98.2 Interstitial emphysema
0.652 0.347 0.000
G81 Hemiplegia
0.652 0.348 0.000
E87.5 Hyperkalaemia
0.652 0.348 0.000
E11.2 With renal complications
0.652 0.348 0.000
I62 Other nontraumatic intracranial haemorrhage
0.651 0.349 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.651 0.349 0.000
R11 Nausea and vomiting
0.650 0.350 0.000
J30 Vasomotor and allergic rhinitis
0.650 0.350 0.000
M84 Disorders of continuity of bone
0.650 0.350 0.000
Z99.8 Dependence on other enabling machines and devices
0.649 0.351 0.000
I60 Subarachnoid haemorrhage
0.648 0.352 0.000
H65 Nonsuppurative otitis media
0.647 0.353 0.000
J37 Chronic laryngitis and laryngotracheitis
0.646 0.354 0.000
M81 Osteoporosis without pathological fracture
0.646 0.354 0.000
N60 Benign mammary dysplasia
0.645 0.355 0.000
F33.9 Recurrent depressive disorder, unspecified
0.645 0.355 0.000
K76 Other diseases of liver
0.644 0.356 0.000
M51 Other intervertebral disk disorders
0.644 0.356 0.000
E80 Disorders of porphyrin and bilirubin metabolism
0.643 0.357 0.000
E11.5 With peripheral circulatory complications
0.643 0.357 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.642 0.358 0.000
Y35-Y36 Legal intervention and operations of war
0.642 0.358 0.000
Y10-Y34 Event of undetermined intent
0.642 0.358 0.000
Y00-Y09 Assault
0.642 0.358 0.000
X85-X99 Assault
0.642 0.358 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.642 0.358 0.000
X50-X57 Overexertion, travel and privation
0.642 0.358 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.642 0.358 0.000
X30-X39 Exposure to forces of nature
0.642 0.358 0.000
X20-X29 Contact with venomous animals and plants
0.642 0.358 0.000
X10-X19 Contact with heat and hot substances
0.642 0.358 0.000
X00-X09 Exposure to smoke, fire and flames
0.642 0.358 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.642 0.358 0.000
W75-W84 Other accidental threats to breathing
0.642 0.358 0.000
W65-W74 Accidental drowning and submersion
0.642 0.358 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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