TreeWAS – Variant ID: rs17064002

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)

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Results table

Term	Risk posterior probability	No effect posterior probability
# Top node	0.999	0.001
Chapter II Neoplasms	0.997	0.003
Chapter IX Diseases of the circulatory system	0.982	0.018
Chapter XIX Injury, poisoning and certain other consequences of external causes	0.973	0.027
D10-D36 Benign neoplasms	0.952	0.048
I20-I25 Ischaemic heart diseases	0.950	0.050
Chapter XV Pregnancy, childbirth and the puerperium	0.943	0.057
Chapter V Mental and behavioural disorders	0.939	0.060
Chapter XXI Factors influencing health status and contact with health services	0.909	0.091
Chapter VII Diseases of the eye and adnexa	0.908	0.092
C43-C44 Melanoma and other malignant neoplasms of skin	0.904	0.096
I25 Chronic ischaemic heart disease	0.893	0.107
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs	0.891	0.109
F10-F19 Mental and behavioural disorders due to psychoactive substance use	0.884	0.116
S00-S09 Injuries to the head	0.879	0.121
C50-C50 Malignant neoplasm of breast	0.877	0.123
T80-T88 Complications of surgical and medical care, not elsewhere classified	0.854	0.146
Chapter XX External causes of morbidity and mortality	0.844	0.156
Chapter X Diseases of the respiratory system	0.842	0.158
C44 Other malignant neoplasms of skin	0.837	0.163
F17 Mental and behavioural disorders due to use of tobacco	0.833	0.167
Z80-Z99 Persons with potential health hazards related to family and personal history and certain conditions influencing health status	0.831	0.169
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites	0.825	0.175
Chapter XII Diseases of the skin and subcutaneous tissue	0.823	0.177
I21 Acute myocardial infarction	0.823	0.177
O20-O29 Other maternal disorders predominantly related to pregnancy	0.819	0.181
D12 Benign neoplasm of colon, rectum, anus and anal canal	0.817	0.183
C34 Malignant neoplasm of bronchus and lung	0.816	0.184
D23 Other benign neoplasms of skin	0.810	0.190
I25.1 Atherosclerotic heart disease	0.809	0.191
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation	0.803	0.197
F17.1 Harmful use	0.797	0.203
S09 Other and unspecified injuries of head	0.796	0.204
O60-O75 Complications of labour and delivery	0.795	0.205
C50 Malignant neoplasm of breast	0.791	0.209
C51-C58 Malignant neoplasms of female genital organs	0.790	0.210
I95-I99 Other and unspecified disorders of the circulatory system	0.788	0.211
H25-H28 Disorders of lens	0.788	0.212
I30-I52 Other forms of heart disease	0.784	0.216
Z87 Personal history of other diseases and conditions	0.782	0.218
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism	0.782	0.218
D22 Melanocytic naevi	0.771	0.229
Z30-Z39 Persons encountering health services in circumstances related to reproduction	0.764	0.235
S80-S89 Injuries to the knee and lower leg	0.764	0.236
S40-S49 Injuries to the shoulder and upper arm	0.763	0.237
Chapter I Certain infectious and parasitic diseases	0.758	0.242
D24 Benign neoplasm of breast	0.753	0.247
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium	0.752	0.248
Chapter VIII Diseases of the ear and mastoid process	0.751	0.249
Z87.4 Personal history of diseases of the genito-urinary system	0.749	0.251
D17 Benign lipomatous neoplasm	0.748	0.251
T81 Complications of procedures, not elsewhere classified	0.748	0.252
C15-C26 Malignant neoplasms of digestive organs	0.741	0.259
F40-F48 Neurotic, stress-related and somatoform disorders	0.740	0.260
S50-S59 Injuries to the elbow and forearm	0.739	0.261
L80-L99 Other disorders of the skin and subcutaneous tissue	0.737	0.263
Z96 Presence of other functional implants	0.736	0.264
S09.9 Unspecified injury of head	0.736	0.264
I80-I89 Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified	0.735	0.265
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source	0.735	0.265
Z70-Z76 Persons encountering health services in other circumstances	0.732	0.268
C44.5 Skin of trunk	0.727	0.273
J90-J94 Other diseases of pleura	0.720	0.280
I20 Angina pectoris	0.719	0.281
C44.2 Skin of ear and external auricular canal	0.717	0.283
Z20-Z29 Persons with potential health hazards related to communicable diseases	0.717	0.283
Chapter XXII Codes for special purposes	0.716	0.284
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities	0.716	0.284
Chapter XVI Certain conditions originating in the perinatal period	0.716	0.284
I25.8 Other forms of chronic ischaemic heart disease	0.715	0.285
D37-D48 Neoplasms of uncertain or unknown behaviour	0.715	0.285
D00-D09 In situ neoplasms	0.715	0.285
C97-C97 Malignant neoplasms of independent (primary) multiple sites	0.715	0.285
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue	0.715	0.285
C73-C75 Malignant neoplasms of thyroid and other endocrine glands	0.715	0.285
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system	0.715	0.285
C45-C49 Malignant neoplasms of mesothelial and soft tissue	0.715	0.285
C40-C41 Malignant neoplasms of bone and articular cartilage	0.715	0.285
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx	0.715	0.285
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction	0.712	0.288
Chapter VI Diseases of the nervous system	0.710	0.289
I10-I15 Hypertensive diseases	0.709	0.291
I21.0 Acute transmural myocardial infarction of anterior wall	0.708	0.292
T36-T50 Poisoning by drugs, medicaments and biological substances	0.706	0.294
I05-I09 Chronic rheumatic heart diseases	0.704	0.296
I00-I02 Acute rheumatic fever	0.704	0.296
O00-O08 Pregnancy with abortive outcome	0.703	0.297
J09-J18 Influenza and pneumonia	0.701	0.299
Z96.1 Presence of intraocular lens	0.700	0.300
I70-I79 Diseases of arteries, arterioles and capillaries	0.699	0.301
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes	0.697	0.303
T79-T79 Certain early complications of trauma	0.697	0.303
T66-T78 Other and unspecified effects of external causes	0.697	0.303
T33-T35 Frostbite	0.697	0.303
T29-T32 Burns and corrosions of multiple and unspecified body regions	0.697	0.303
T26-T28 Burns and corrosions confined to eye and internal organs	0.697	0.303
T20-T25 Burns and corrosions of external body surface, specified by site	0.697	0.303
T15-T19 Effects of foreign body entering through natural orifice	0.697	0.303
T08-T14 Injuries to unspecified part of trunk, limb or body region	0.697	0.303
T00-T07 Injuries involving multiple body regions	0.697	0.303
S90-S99 Injuries to the ankle and foot	0.697	0.303
S70-S79 Injuries to the hip and thigh	0.697	0.303
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis	0.697	0.303
S20-S29 Injuries to the thorax	0.697	0.303
S10-S19 Injuries to the neck	0.697	0.303
D12.5 Sigmoid colon	0.697	0.303
O80-O84 Delivery	0.697	0.303
C34.9 Bronchus or lung, unspecified	0.696	0.304
I25.9 Chronic ischaemic heart disease, unspecified	0.696	0.304
D27 Benign neoplasm of ovary	0.691	0.309
F10 Mental and behavioural disorders due to use of alcohol	0.690	0.310
C64-C68 Malignant neoplasms of urinary tract	0.688	0.311
O26 Maternal care for other conditions predominantly related to pregnancy	0.687	0.313
C77 Secondary and unspecified malignant neoplasm of lymph nodes	0.687	0.313
T85 Complications of other internal prosthetic devices, implants and grafts	0.684	0.316
Z85 Personal history of malignant neoplasm	0.684	0.316
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems	0.684	0.316
C50.4 Upper-outer quadrant of breast	0.683	0.317
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified	0.683	0.317
D36 Benign neoplasm of other and unspecified sites	0.683	0.317
D35 Benign neoplasm of other and unspecified endocrine glands	0.683	0.317
D33 Benign neoplasm of brain and other parts of central nervous system	0.683	0.317
D32 Benign neoplasm of meninges	0.683	0.317
D31 Benign neoplasm of eye and adnexa	0.683	0.317
D30 Benign neoplasm of urinary organs	0.683	0.317
D29 Benign neoplasm of male genital organs	0.683	0.317
D28 Benign neoplasm of other and unspecified female genital organs	0.683	0.317
D26 Other benign neoplasms of uterus	0.683	0.317
D21 Other benign neoplasms of connective and other soft tissue	0.683	0.317
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum	0.683	0.317
D19 Benign neoplasm of mesothelial tissue	0.683	0.317
D18 Haemangioma and lymphangioma, any site	0.683	0.317
D16 Benign neoplasm of bone and articular cartilage	0.683	0.317
D15 Benign neoplasm of other and unspecified intrathoracic organs	0.683	0.317
D14 Benign neoplasm of middle ear and respiratory system	0.683	0.317
D13 Benign neoplasm of other and ill-defined parts of digestive system	0.683	0.317
D11 Benign neoplasm of major salivary glands	0.683	0.317
D10 Benign neoplasm of mouth and pharynx	0.683	0.317
D34 Benign neoplasm of thyroid gland	0.683	0.317
L98 Other disorders of skin and subcutaneous tissue, not elsewhere classified	0.682	0.318
H53-H54 Visual disturbances and blindness	0.682	0.318
C50.2 Upper-inner quadrant of breast	0.681	0.319
I24 Other acute ischaemic heart diseases	0.681	0.319
I23 Certain current complications following acute myocardial infarction	0.681	0.319
I22 Subsequent myocardial infarction	0.681	0.319
S01 Open wound of head	0.680	0.320
H30-H36 Disorders of choroid and retina	0.679	0.320
O94-O99 Other obstetric conditions, not elsewhere classified	0.676	0.324
O85-O92 Complications predominantly related to the puerperium	0.676	0.324
I26 Pulmonary embolism	0.675	0.325
F99-F99 Unspecified mental disorder	0.674	0.326
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence	0.674	0.326
F80-F89 Disorders of psychological development	0.674	0.326
F70-F79 Mental retardation	0.674	0.326
F60-F69 Disorders of adult personality and behaviour	0.674	0.326
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors	0.674	0.326
F20-F29 Schizophrenia, schizotypal and delusional disorders	0.674	0.326
F00-F09 Organic, including symptomatic, mental disorders	0.674	0.326
H40-H42 Glaucoma	0.673	0.327
Z37 Outcome of delivery	0.673	0.327
H26 Other cataract	0.670	0.330
I25.2 Old myocardial infarction	0.669	0.331
F30-F39 Mood [affective] disorders	0.666	0.334
D12.0 Caecum	0.665	0.335
O20 Haemorrhage in early pregnancy	0.662	0.338
C34.3 Lower lobe, bronchus or lung	0.662	0.338
I21.4 Acute subendocardial myocardial infarction	0.659	0.341
C34.1 Upper lobe, bronchus or lung	0.659	0.341
J30-J39 Other diseases of upper respiratory tract	0.659	0.341
W00-W19 Falls	0.658	0.342
Z55-Z65 Persons with potential health hazards related to socioeconomic and psychosocial circumstances	0.657	0.343
Y60-Y69 Misadventures to patients during surgical and medical care	0.655	0.345
S60-S69 Injuries to the wrist and hand	0.655	0.345
C44.1 Skin of eyelid, including canthus	0.654	0.346
O70 Perineal laceration during delivery	0.651	0.349
H55-H59 Other disorders of eye and adnexa	0.651	0.349
H46-H48 Disorders of optic nerve and visual pathways	0.651	0.349
H43-H45 Disorders of vitreous body and globe	0.651	0.349
H15-H22 Disorders of sclera, cornea, iris and ciliary body	0.651	0.349
H10-H13 Disorders of conjunctiva	0.651	0.349
H00-H06 Disorders of eyelid, lacrimal system and orbit	0.650	0.350
I95 Hypotension	0.650	0.350
D23.6 Skin of upper limb, including shoulder	0.648	0.352
C43 Malignant melanoma of skin	0.648	0.352
Chapter XI Diseases of the digestive system	0.646	0.354
L98.9 Disorder of skin and subcutaneous tissue, unspecified	0.642	0.358
I49 Other cardiac arrhythmias	0.641	0.358
Z82 Family history of certain disabilities and chronic diseases leading to disablement	0.641	0.359
I25.6 Silent myocardial ischaemia	0.640	0.360
I25.5 Ischaemic cardiomyopathy	0.640	0.360
I25.4 Coronary artery aneurysm	0.640	0.360
I25.3 Aneurysm of heart	0.640	0.360
I25.0 Atherosclerotic cardiovascular disease, so described	0.640	0.360
C39 Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs	0.639	0.361
C38 Malignant neoplasm of heart, mediastinum and pleura	0.639	0.361
C32 Malignant neoplasm of larynx	0.639	0.361
C31 Malignant neoplasm of accessory sinuses	0.639	0.361
C30 Malignant neoplasm of nasal cavity and middle ear	0.639	0.361
C37 Malignant neoplasm of thymus	0.639	0.361
C33 Malignant neoplasm of trachea	0.639	0.361
D23.7 Skin of lower limb, including hip	0.638	0.362
D50-D53 Nutritional anaemias	0.637	0.363
R10-R19 Symptoms and signs involving the digestive system and abdomen	0.637	0.363
O68 Labour and delivery complicated by foetal stress [distress]	0.636	0.364
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances	0.634	0.366
F18 Mental and behavioural disorders due to use of volatile solvents	0.634	0.366
F16 Mental and behavioural disorders due to use of hallucinogens	0.634	0.366
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine	0.634	0.366
F14 Mental and behavioural disorders due to use of cocaine	0.634	0.366
F13 Mental and behavioural disorders due to use of sedatives or hypnotics	0.634	0.366
F12 Mental and behavioural disorders due to use of cannabinoids	0.634	0.366
F11 Mental and behavioural disorders due to use of opioids	0.634	0.366
Y85-Y89 Sequelae of external causes of morbidity and mortality	0.634	0.366
J90 Pleural effusion, not elsewhere classified	0.633	0.367
S08 Traumatic amputation of part of head	0.630	0.370
S07 Crushing injury of head	0.630	0.370
S06 Intracranial injury	0.630	0.370
S05 Injury of eye and orbit	0.630	0.370
S04 Injury of cranial nerves	0.630	0.370
S03 Dislocation, sprain and strain of joints and ligaments of head	0.630	0.370
S02 Fracture of skull and facial bones	0.630	0.370
S00 Superficial injury of head	0.630	0.370
C79 Secondary malignant neoplasm of other sites	0.630	0.370
D17.0 Benign lipomatous neoplasm of skin and subcutaneous tissue of head, face and neck	0.629	0.371
H25 Senile cataract	0.625	0.375
D22.3 Melanocytic naevi of other and unspecified parts of face	0.625	0.375
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use	0.624	0.376
I60-I69 Cerebrovascular diseases	0.623	0.377
D25 Leiomyoma of uterus	0.621	0.379
D12.2 Ascending colon	0.620	0.380
J95-J99 Other diseases of the respiratory system	0.619	0.380
I21.1 Acute transmural myocardial infarction of inferior wall	0.619	0.381
C56 Malignant neoplasm of ovary	0.619	0.381
D65-D69 Coagulation defects, purpura and other haemorrhagic conditions	0.617	0.382
D23.1 Skin of eyelid, including canthus	0.617	0.383
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere	0.617	0.383
C44.6 Skin of upper limb, including shoulder	0.615	0.385
Z83 Family history of other specific disorders	0.615	0.385
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts	0.615	0.385
O16 Unspecified maternal hypertension	0.614	0.386
S82 Fracture of lower leg, including ankle	0.614	0.386
I83 Varicose veins of lower extremities	0.613	0.387
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle	0.613	0.387
T88 Other complications of surgical and medical care, not elsewhere classified	0.612	0.388
T87 Complications peculiar to reattachment and amputation	0.612	0.388
T86 Failure and rejection of transplanted organs and tissues	0.612	0.388
T83 Complications of genito-urinary prosthetic devices, implants and grafts	0.612	0.388
T80 Complications following infusion, transfusion and therapeutic injection	0.612	0.388
D12.8 Rectum	0.611	0.389
I44 Atrioventricular and left bundle-branch block	0.608	0.392
Z37.0 Single live birth	0.607	0.393
Y83-Y84 Surgical and other medical procedures as the cause of abnormal reaction of the patient, or of later complication, without mention of misadventure at the time of the procedure	0.607	0.393
Z91 Personal history of risk-factors, not elsewhere classified	0.606	0.394
B95-B98 Bacterial, viral and other infectious agents	0.605	0.395
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use	0.605	0.395
Y35-Y36 Legal intervention and operations of war	0.605	0.395
Y10-Y34 Event of undetermined intent	0.605	0.395
Y00-Y09 Assault	0.605	0.395
X85-X99 Assault	0.605	0.395
X60-X84 Intentional self-harm	0.605	0.395
X58-X59 Accidental exposure to other and unspecified factors	0.605	0.395
X50-X57 Overexertion, travel and privation	0.605	0.395
X40-X49 Accidental poisoning by and exposure to noxious substances	0.605	0.395
X30-X39 Exposure to forces of nature	0.605	0.395
X20-X29 Contact with venomous animals and plants	0.605	0.395
X10-X19 Contact with heat and hot substances	0.605	0.395
X00-X09 Exposure to smoke, fire and flames	0.605	0.395
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure	0.605	0.395
W75-W84 Other accidental threats to breathing	0.605	0.395
W65-W74 Accidental drowning and submersion	0.605	0.395
W50-W64 Exposure to animate mechanical forces	0.605	0.395
W20-W49 Exposure to inanimate mechanical forces	0.605	0.395
V98-V99 Other and unspecified transport accidents	0.605	0.395
V95-V97 Air and space transport accidents	0.605	0.395
V90-V94 Water transport accidents	0.605	0.395
V80-V89 Other land transport accidents	0.605	0.395
V70-V79 Bus occupant injured in transport accident	0.605	0.395
V60-V69 Occupant of heavy transport vehicle injured in transport accident	0.605	0.395
V50-V59 Occupant of pick-up truck or van injured in transport accident	0.605	0.395
V40-V49 Car occupant injured in transport accident	0.605	0.395
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident	0.605	0.395
V20-V29 Motorcycle rider injured in transport accident	0.605	0.395
V10-V19 Pedal cyclist injured in transport accident	0.605	0.395
V01-V09 Pedestrian injured in transport accident	0.605	0.395
Z98 Other postsurgical states	0.605	0.395
T81.8 Other complications of procedures, not elsewhere classified	0.604	0.396
J85-J86 Suppurative and necrotic conditions of lower respiratory tract	0.603	0.396
J80-J84 Other respiratory diseases principally affecting the interstitium	0.603	0.396
J60-J70 Lung diseases due to external agents	0.603	0.396
J00-J06 Acute upper respiratory infections	0.603	0.396
J18 Pneumonia, organism unspecified	0.601	0.399
Z87.3 Personal history of diseases of the musculoskeletal system and connective tissue	0.601	0.399
C44.9 Malignant neoplasm of skin, unspecified	0.600	0.400
C44.8 Overlapping lesion of skin	0.600	0.400
C44.7 Skin of lower limb, including hip	0.600	0.400
C44.0 Skin of lip	0.600	0.400
T81.2 Accidental puncture and laceration during a procedure, not elsewhere classified	0.600	0.400
Z88 Personal history of allergy to drugs, medicaments and biologocal substances	0.599	0.401
L40-L45 Papulosquamous disorders	0.598	0.402
F17.9 Unspecified mental and behavioural disorder	0.597	0.402
F17.8 Other mental and behavioural disorders	0.597	0.402
F17.7 Residual and late-onset psychotic disorder	0.597	0.402
F17.6 Amnesic syndrome	0.597	0.402
F17.5 Psychotic disorder	0.597	0.402
F17.4 Withdrawal state with delirium	0.597	0.402
F17.3 Withdrawal state	0.597	0.402
F17.2 Dependence syndrome	0.597	0.402
F17.0 Acute intoxication	0.597	0.402
F41 Other anxiety disorders	0.597	0.403
Z99 Dependence on enabling machines and devices, not elsewhere classified	0.595	0.404
Z97 Presence of other devices	0.595	0.404
Z94 Transplanted organ and tissue status	0.595	0.404
Z93 Artificial opening status	0.595	0.404
Z89 Acquired absence of limb	0.595	0.404
Z84 Family history of other conditions	0.595	0.404
Z81 Family history of mental and behavioural disorders	0.595	0.404
C54 Malignant neoplasm of corpus uteri	0.595	0.405
Z75 Problems related to medical facilities and other health care	0.595	0.405
C44.4 Skin of scalp and neck	0.593	0.406
O26.8 Other specified pregnancy-related conditions	0.593	0.407
Z92 Personal history of medical treatment	0.593	0.407
C80 Malignant neoplasm without specification of site	0.591	0.409
C76 Malignant neoplasm of other and ill-defined sites	0.591	0.409
L50-L54 Urticaria and erythema	0.590	0.410
L20-L30 Dermatitis and eczema	0.590	0.410
L10-L14 Bullous disorders	0.590	0.410
I21.X Presumed acute myicardial infaction (unconfirmed)	0.590	0.410
I21.3 Acute transmural myocardial infarction of unspecified site	0.590	0.410
I21.2 Acute transmural myocardial infarction of other sites	0.590	0.410
O29 Complications of anaesthesia during pregnancy	0.587	0.413
O28 Abnormal findings on antenatal screening of mother	0.587	0.413
O24 Diabetes mellitus in pregnancy	0.587	0.413
O23 Infections of genito-urinary tract in pregnancy	0.587	0.413
O22 Venous complications in pregnancy	0.587	0.413
O21 Excessive vomiting in pregnancy	0.587	0.413
O25 Malnutrition in pregnancy	0.587	0.413
D12.9 Anus and anal canal	0.586	0.414
D12.7 Rectosigmoid junction	0.586	0.414
D12.1 Appendix	0.586	0.414
H26.9 Cataract, unspecified	0.585	0.415
C34.8 Overlapping lesion of bronchus and lung	0.585	0.415
C34.2 Middle lobe, bronchus or lung	0.585	0.415
C34.0 Main bronchus	0.585	0.415
Z85.8 Personal history of malignant neoplasms of other organs and systems	0.584	0.416
I26.9 Pulmonary embolism without mention of acute cor pulmonale	0.583	0.417
R19 Other symptoms and signs involving the digestive system and abdomen	0.582	0.418
D12.4 Descending colon	0.582	0.418
Z95 Presence of cardiac and vascular implants and grafts	0.581	0.419
D23.9 Skin, unspecified	0.581	0.419
D23.5 Skin of trunk	0.581	0.419
D23.4 Skin of scalp and neck	0.581	0.419
D23.3 Skin of other and unspecified parts of face	0.581	0.419
D23.2 Skin of ear and external auricular canal	0.581	0.419
D23.0 Skin of lip	0.581	0.419
Z22 Carrier of infectious disease	0.579	0.421
I50 Heart failure	0.577	0.423
D22.5 Melanocytic naevi of trunk	0.577	0.423
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts	0.576	0.424
I28 Other diseases of pulmonary vessels	0.576	0.424
I27 Other pulmonary heart diseases	0.576	0.424
C78 Secondary malignant neoplasm of respiratory and digestive organs	0.574	0.426
H80-H83 Diseases of inner ear	0.574	0.426
T81.3 Disruption of operation wound, not elsewhere classified	0.573	0.427
H52 Disorders of refraction and accommodation	0.572	0.428
S52 Fracture of forearm	0.571	0.429
S09.8 Other specified injuries of head	0.570	0.429
S09.7 Multiple injuries of head	0.570	0.429
S09.2 Traumatic rupture of ear drum	0.570	0.429
S09.1 Injury of muscle and tendon of head	0.570	0.429
S09.0 Injury of blood vessels of head, not elsewhere classified	0.570	0.429
C77.1 Intrathoracic lymph nodes	0.570	0.429
O75 Other complications of labour and delivery, not elsewhere classified	0.570	0.430
O74 Complications of anaesthesia during labour and delivery	0.570	0.430
O73 Retained placenta and membranes, without haemorrhage	0.570	0.430
O72 Postpartum haemorrhage	0.570	0.430
O71 Other obstetric trauma	0.570	0.430
O69 Labour and delivery complicated by umbilical cord complications	0.570	0.430
O67 Labour and delivery complicated by intrapartum haemorrhage, not elsewhere classified	0.570	0.430
O66 Other obstructed labour	0.570	0.430
O65 Obstructed labour due to maternal pelvic abnormality	0.570	0.430
O64 Obstructed labour due to malposition and malpresentation of foetus	0.570	0.430
O62 Abnormalities of forces of labour	0.570	0.430
O61 Failed induction of labour	0.570	0.430
O60 Preterm delivery	0.570	0.430
C50.8 Overlapping lesion of breast	0.567	0.433
C50.6 Axillary tail of breast	0.567	0.433
C50.5 Lower-outer quadrant of breast	0.567	0.433
C50.3 Lower-inner quadrant of breast	0.567	0.433
C50.1 Central portion of breast	0.567	0.433
C50.0 Nipple and areola	0.567	0.433
C44.3 Skin of other and unspecified parts of face	0.567	0.433
C57 Malignant neoplasm of other and unspecified female genital organs	0.566	0.434
C53 Malignant neoplasm of cervix uteri	0.566	0.434
C51 Malignant neoplasm of vulva	0.566	0.434
C58 Malignant neoplasm of placenta	0.566	0.434
C55 Malignant neoplasm of uterus, part unspecified	0.566	0.434
C52 Malignant neoplasm of vagina	0.566	0.434
L60-L75 Disorders of skin appendages	0.566	0.434
I98 Other disorders of circulatory system in diseases classified elsewhere	0.565	0.435
I97 Postprocedural disorders of circulatory system, not elsewhere classified	0.565	0.435
I99 Other and unspecified disorders of circulatory system	0.565	0.435
H28 Cataract and other disorders of lens in diseases classified elsewhere	0.565	0.435
H27 Other disorders of lens	0.565	0.435
T51 Toxic effect of alcohol	0.564	0.435
F10.1 Harmful use	0.563	0.437
T85.7 Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts	0.563	0.437
I52 Other heart disorders in diseases classified elsewhere	0.562	0.438
I48 Atrial fibrillation and flutter	0.562	0.438
I46 Cardiac arrest	0.562	0.438
I43 Cardiomyopathy in diseases classified elsewhere	0.562	0.438
I42 Cardiomyopathy	0.562	0.438
I41 Myocarditis in diseases classified elsewhere	0.562	0.438
I40 Acute myocarditis	0.562	0.438
I39 Endocarditis and heart valve disorders in diseases classified elsewhere	0.562	0.438
I37 Pulmonary valve disorders	0.562	0.438
I36 Nonrheumatic tricuspid valve disorders	0.562	0.438
I33 Acute and subacute endocarditis	0.562	0.438
I32 Pericarditis in diseases classified elsewhere	0.562	0.438
I31 Other diseases of pericardium	0.562	0.438
I30 Acute pericarditis	0.562	0.438
I38 Endocarditis, valve unspecified	0.562	0.438
Z87.8 Personal history of other specified conditions	0.561	0.439
Z87.7 Personal history of congenital malformations, deformations and chromosomal abnormalities	0.561	0.439
Z87.6 Personal history of certain conditions arising in the perinatal period	0.561	0.439
Z87.5 Personal history of complications of pregnancy, childbirth and the puerperium	0.561	0.439
Z87.2 Personal history of diseases of the skin and subcutaneous tissue	0.561	0.439
D80-D89 Certain disorders involving the immune mechanism	0.560	0.439
D55-D59 Haemolytic anaemias	0.560	0.439
T81.4 Infection following a procedure, not elsewhere classified	0.560	0.440
O63 Long labour	0.560	0.440
I20.9 Angina pectoris, unspecified	0.559	0.441
Z96.0 Presence of urogenital implants	0.558	0.442
I45 Other conduction disorders	0.557	0.442
D70-D77 Other diseases of blood and blood-forming organs	0.557	0.443
R11 Nausea and vomiting	0.556	0.444
L55-L59 Radiation-related disorders of the skin and subcutaneous tissue	0.553	0.446
D22.9 Melanocytic naevi, unspecified	0.553	0.447
D22.7 Melanocytic naevi of lower limb, including hip	0.553	0.447
D22.6 Melanocytic naevi of upper limb, including shoulder	0.553	0.447
D22.4 Melanocytic naevi of scalp and neck	0.553	0.447
D22.2 Melanocytic naevi of ear and external auricular canal	0.553	0.447
D22.1 Melanocytic naevi of eyelid, including canthus	0.553	0.447
D22.0 Melanocytic naevi of lip	0.553	0.447
I35 Nonrheumatic aortic valve disorders	0.552	0.448
A30-A49 Other bacterial diseases	0.551	0.448
I95.9 Hypotension, unspecified	0.550	0.450
C20 Malignant neoplasm of rectum	0.550	0.450
O20.0 Threatened abortion	0.550	0.450
I47 Paroxysmal tachycardia	0.549	0.451
L00-L08 Infections of the skin and subcutaneous tissue	0.549	0.451
O70.1 Second degree perineal laceration during delivery	0.549	0.451
L91 Hypertrophic disorders of skin	0.548	0.452
Z39 Postpartum care and examination	0.548	0.452
Z38 Liveborn infants according to place of birth	0.548	0.452
Z36 Antenatal screening	0.548	0.452
Z35 Supervision of high-risk pregnancy	0.548	0.452
Z34 Supervision of normal pregnancy	0.548	0.452
Z32 Pregnancy examination and test	0.548	0.452
Z31 Procreative management	0.548	0.452
Z33 Pregnant state, incidental	0.548	0.452
S89 Other and unspecified injuries of lower leg	0.548	0.452
S88 Traumatic amputation of lower leg	0.548	0.452
S87 Crushing injury of lower leg	0.548	0.452
S86 Injury of muscle and tendon at lower leg level	0.548	0.452
S85 Injury of blood vessels at lower leg level	0.548	0.452
S84 Injury of nerves at lower leg level	0.548	0.452
S83 Dislocation, sprain and strain of joints and ligaments of knee	0.548	0.452
S81 Open wound of lower leg	0.548	0.452
S80 Superficial injury of lower leg	0.548	0.452
S49 Other and unspecified injuries of shoulder and upper arm	0.547	0.453
S48 Traumatic amputation of shoulder and upper arm	0.547	0.453
S46 Injury of muscle and tendon at shoulder and upper arm level	0.547	0.453
S45 Injury of blood vessels at shoulder and upper arm level	0.547	0.453
S44 Injury of nerves at shoulder and upper arm level	0.547	0.453
S42 Fracture of shoulder and upper arm	0.547	0.453
S41 Open wound of shoulder and upper arm	0.547	0.453
S40 Superficial injury of shoulder and upper arm	0.547	0.453
S47 Crushing injury of shoulder and upper arm	0.547	0.453
I51 Complications and ill-defined descriptions of heart disease	0.545	0.455
Z87.1 Personal history of diseases of the digestive system	0.545	0.455
B99-B99 Other infectious diseases	0.543	0.456
B90-B94 Sequelae of infectious and parasitic diseases	0.543	0.456
B85-B89 Pediculosis, acariasis and other infestations	0.543	0.456
B65-B83 Helminthiases	0.543	0.456
B50-B64 Protozoal diseases	0.543	0.456
B35-B49 Mycoses	0.543	0.456
B20-B24 Human immunodeficiency virus [HIV] disease	0.543	0.456
B15-B19 Viral hepatitis	0.543	0.456
B00-B09 Viral infections characterized by skin and mucous membrane lesions	0.543	0.456
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers	0.543	0.456
A80-A89 Viral infections of the central nervous system	0.543	0.456
A75-A79 Rickettsioses	0.543	0.456
A70-A74 Other diseases caused by chlamydiae	0.543	0.456
A65-A69 Other spirochaetal diseases	0.543	0.456
A50-A64 Infections with a predominantly sexual mode of transmission	0.543	0.456
A20-A28 Certain zoonotic bacterial diseases	0.543	0.456
A15-A19 Tuberculosis	0.543	0.456
Z85.1 Personal history of malignant neoplasm of trachea, bronchus and lung	0.542	0.458
H33 Retinal detachments and breaks	0.542	0.458
Z72 Problems related to lifestyle	0.541	0.459

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

Variant-specific associations