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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17176768
log Bayes Factor = 11.8039
Chromosome 14   position 37,151,905  (GRCh37) Explore rs17176768 on Ensembl!
Variant rs17176768 is part of Cluster X0072

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
Chapter XIX Injury, poisoning and certain other consequences of external causes
1.000 0.000 0.000
# Top node
1.000 0.000 0.000
Chapter VI Diseases of the nervous system
1.000 0.000 0.000
G40 Epilepsy
1.000 0.000 0.000
G40-G47 Episodic and paroxysmal disorders
1.000 0.000 0.000
G40.9 Epilepsy, unspecified
0.999 0.001 0.000
Chapter VII Diseases of the eye and adnexa
0.998 0.002 0.000
Chapter V Mental and behavioural disorders
0.996 0.004 0.000
Chapter IX Diseases of the circulatory system
0.988 0.012 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.987 0.013 0.000
H30-H36 Disorders of choroid and retina
0.985 0.015 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
0.981 0.019 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.979 0.021 0.000
R40-R46 Symptoms and signs involving cognition, perception, emotional state and behaviour
0.974 0.026 0.000
F10-F19 Mental and behavioural disorders due to psychoactive substance use
0.973 0.027 0.000
G90-G99 Other disorders of the nervous system
0.972 0.028 0.000
F10 Mental and behavioural disorders due to use of alcohol
0.964 0.036 0.000
I73 Other peripheral vascular diseases
0.963 0.037 0.000
S00-S09 Injuries to the head
0.963 0.037 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.960 0.040 0.000
R39 Other symptoms and signs involving the urinary system
0.959 0.041 0.000
R30-R39 Symptoms and signs involving the urinary system
0.959 0.041 0.000
F00-F09 Organic, including symptomatic, mental disorders
0.958 0.042 0.000
R39.8 Other and unspecified symptoms and signs involving the urinary system
0.954 0.046 0.000
T51-T65 Toxic effects of substances chiefly nonmedicinal as to source
0.952 0.048 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.951 0.049 0.000
I73.9 Peripheral vascular disease, unspecified
0.950 0.050 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.947 0.053 0.000
H15-H22 Disorders of sclera, cornea, iris and ciliary body
0.947 0.053 0.000
S40-S49 Injuries to the shoulder and upper arm
0.944 0.056 0.000
I72 Other aneurysm
0.938 0.062 0.000
Chapter I Certain infectious and parasitic diseases
0.934 0.066 0.000
G47 Sleep disorders
0.930 0.070 0.000
G30-G32 Other degenerative diseases of the nervous system
0.925 0.075 0.000
R39.1 Other difficulties with micturition
0.920 0.080 0.000
H35 Other retinal disorders
0.916 0.084 0.000
H40-H42 Glaucoma
0.914 0.086 0.000
Chapter XX External causes of morbidity and mortality
0.913 0.087 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.912 0.088 0.000
T82.8 Other complications of cardiac and vascular prosthetic devices, implants and grafts
0.909 0.091 0.000
T51 Toxic effect of alcohol
0.907 0.093 0.000
F05 Delirium, not induced by alcohol and other psychoactive substances
0.905 0.095 0.000
G93 Other disorders of brain
0.897 0.103 0.000
H55-H59 Other disorders of eye and adnexa
0.891 0.109 0.000
H33 Retinal detachments and breaks
0.890 0.110 0.000
R41 Other symptoms and signs involving cognitive functions and awareness
0.886 0.114 0.000
T36-T50 Poisoning by drugs, medicaments and biological substances
0.882 0.118 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.879 0.121 0.000
T51.0 Ethanol
0.876 0.124 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.875 0.125 0.000
R42 Dizziness and giddiness
0.875 0.125 0.000
S01 Open wound of head
0.874 0.126 0.000
G47.3 Sleep apnoea
0.871 0.129 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.870 0.130 0.000
H34 Retinal vascular occlusions
0.868 0.132 0.000
G91 Hydrocephalus
0.868 0.132 0.000
F05.9 Delirium, unspecified
0.866 0.134 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.861 0.139 0.000
Q00-Q07 Congenital malformations of the nervous system
0.858 0.142 0.000
F10.3 Withdrawal state
0.857 0.143 0.000
F10.0 Acute intoxication
0.857 0.143 0.000
I77 Other disorders of arteries and arterioles
0.856 0.144 0.000
H40 Glaucoma
0.854 0.146 0.000
H18 Other disorders of cornea
0.853 0.147 0.000
R45 Symptoms and signs involving emotional state
0.852 0.148 0.000
S10-S19 Injuries to the neck
0.851 0.149 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.849 0.151 0.000
I78 Diseases of capillaries
0.849 0.151 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.846 0.154 0.000
S60-S69 Injuries to the wrist and hand
0.845 0.155 0.000
I30-I52 Other forms of heart disease
0.844 0.156 0.000
S09 Other and unspecified injuries of head
0.840 0.160 0.000
B15-B19 Viral hepatitis
0.839 0.161 0.000
S80-S89 Injuries to the knee and lower leg
0.838 0.162 0.000
F10.5 Psychotic disorder
0.837 0.163 0.000
I72.4 Aneurysm of artery of lower extremity
0.836 0.164 0.000
S00 Superficial injury of head
0.835 0.165 0.000
I47 Paroxysmal tachycardia
0.834 0.166 0.000
B95-B98 Bacterial, viral and other infectious agents
0.832 0.168 0.000
F10.1 Harmful use
0.828 0.172 0.000
G97 Postprocedural disorders of nervous system, not elsewhere classified
0.827 0.173 0.000
Q20-Q28 Congenital malformations of the circulatory system
0.826 0.173 0.000
G31 Other degenerative diseases of nervous system, not elsewhere classified
0.825 0.175 0.000
R40 Somnolence, stupor and coma
0.824 0.176 0.000
I71 Aortic aneurysm and dissection
0.816 0.184 0.000
G93.6 Cerebral oedema
0.815 0.185 0.000
G96 Other disorders of central nervous system
0.815 0.185 0.000
H31 Other disorders of choroid
0.814 0.186 0.000
F20-F29 Schizophrenia, schizotypal and delusional disorders
0.812 0.188 0.000
S50-S59 Injuries to the elbow and forearm
0.811 0.189 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.811 0.189 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.810 0.190 0.000
R41.0 Disorientation, unspecified
0.810 0.190 0.000
S20-S29 Injuries to the thorax
0.810 0.190 0.000
S05 Injury of eye and orbit
0.810 0.190 0.000
I72.3 Aneurysm of iliac artery
0.807 0.193 0.000
S46 Injury of muscle and tendon at shoulder and upper arm level
0.807 0.193 0.000
Y40 Systemic antibiotics
0.806 0.194 0.000
H40.9 Glaucoma, unspecified
0.804 0.196 0.000
F00 Dementia in Alzheimer's disease
0.799 0.201 0.000
Chapter XXII Codes for special purposes
0.798 0.202 0.000
I60-I69 Cerebrovascular diseases
0.797 0.203 0.000
H35.0 Background retinopathy and retinal vascular changes
0.797 0.203 0.000
S80 Superficial injury of lower leg
0.795 0.205 0.000
T82.5 Mechanical complication of other cardiac and vascular devices and implants
0.793 0.207 0.000
S40 Superficial injury of shoulder and upper arm
0.792 0.208 0.000
F13 Mental and behavioural disorders due to use of sedatives or hypnotics
0.792 0.208 0.000
I47.1 Supraventricular tachycardia
0.791 0.209 0.000
G91.9 Hydrocephalus, unspecified
0.789 0.211 0.000
F10.4 Withdrawal state with delirium
0.788 0.212 0.000
S41 Open wound of shoulder and upper arm
0.788 0.212 0.000
R44 Other symptoms and signs involving general sensations and perceptions
0.787 0.213 0.000
F01 Vascular dementia
0.787 0.213 0.000
G40.8 Other epilepsy
0.785 0.215 0.000
Y52 Agents primarily affecting the cardiovascular system
0.784 0.216 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.783 0.217 0.000
S70-S79 Injuries to the hip and thigh
0.782 0.218 0.000
G30 Alzheimer's disease
0.782 0.218 0.000
H34.8 Other retinal vascular occlusions
0.781 0.219 0.000
S90-S99 Injuries to the ankle and foot
0.779 0.221 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.778 0.222 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.777 0.223 0.000
I60 Subarachnoid haemorrhage
0.776 0.224 0.000
H33.0 Retinal detachment with retinal break
0.776 0.224 0.000
T90 Sequelae of injuries of head
0.776 0.224 0.000
H46-H48 Disorders of optic nerve and visual pathways
0.776 0.224 0.000
Q07 Other congenital malformations of nervous system
0.776 0.224 0.000
T23 Burn and corrosion of wrist and hand
0.776 0.224 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.768 0.232 0.000
S62 Fracture at wrist and hand level
0.768 0.232 0.000
S01.1 Open wound of eyelid and periocular area
0.767 0.233 0.000
F99-F99 Unspecified mental disorder
0.766 0.234 0.000
H20 Iridocyclitis
0.766 0.234 0.000
R29 Other symptoms and signs involving the nervous and musculoskeletal systems
0.763 0.237 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.761 0.239 0.000
F80-F89 Disorders of psychological development
0.760 0.240 0.000
H57 Other disorders of eye and adnexa
0.760 0.240 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
H16 Keratitis
0.758 0.242 0.000
T79-T79 Certain early complications of trauma
0.758 0.242 0.000
T43 Poisoning by psychotropic drugs, not elsewhere classified
0.757 0.243 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.755 0.245 0.000
I60.9 Subarachnoid haemorrhage, unspecified
0.755 0.245 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.753 0.247 0.000
T82.3 Mechanical complication of other vascular grafts
0.752 0.248 0.000
I72.8 Aneurysm of other specified arteries
0.752 0.248 0.000
S01.0 Open wound of scalp
0.750 0.250 0.000
G47.1 Disorders of excessive somnolence [hypersomnias]
0.742 0.257 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.741 0.259 0.000
S01.5 Open wound of lip and oral cavity
0.740 0.260 0.000
S32 Fracture of lumbar spine and pelvis
0.740 0.260 0.000
H35.2 Other proliferative retinopathy
0.740 0.260 0.000
I47.2 Ventricular tachycardia
0.739 0.261 0.000
S09.9 Unspecified injury of head
0.739 0.261 0.000
A30-A49 Other bacterial diseases
0.739 0.261 0.000
H35.3 Degeneration of macula and posterior pole
0.738 0.262 0.000
I71.4 Abdominal aortic aneurysm, without mention of rupture
0.738 0.262 0.000
T87 Complications peculiar to reattachment and amputation
0.737 0.263 0.000
R35 Polyuria
0.737 0.263 0.000
G70-G73 Diseases of myoneural junction and muscle
0.734 0.266 0.000
T58 Toxic effect of carbon monoxide
0.734 0.266 0.000
I47.0 Reentry ventricular arrhythmia
0.733 0.267 0.000
G31.9 Degenerative disease of nervous system, unspecified
0.732 0.268 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.732 0.268 0.000
R03.0 Elevated blood-pressure reading, without diagnosis of hypertension
0.731 0.269 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.730 0.270 0.000
Q38-Q45 Other congenital malformations of the digestive system
0.730 0.270 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.730 0.270 0.000
T40 Poisoning by narcotics and psychodysleptics [hallucinogens]
0.729 0.271 0.000
T84.2 Mechanical complication of internal fixation device of other bones
0.729 0.271 0.000
S66 Injury of muscle and tendon at wrist and hand level
0.729 0.271 0.000
H55 Nystagmus and other irregular eye movements
0.729 0.271 0.000
I45 Other conduction disorders
0.727 0.273 0.000
R04 Haemorrhage from respiratory passages
0.727 0.273 0.000
R47-R49 Symptoms and signs involving speech and voice
0.727 0.273 0.000
I78.1 Naevus, nonneoplastic
0.726 0.273 0.000
S01.9 Open wound of head, part unspecified
0.726 0.274 0.000
Q27 Other congenital malformations of peripheral vascular system
0.723 0.277 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.722 0.278 0.000
H40.1 Primary open-angle glaucoma
0.721 0.279 0.000
F40-F48 Neurotic, stress-related and somatoform disorders
0.721 0.279 0.000
Y40.0 Penicillins
0.721 0.279 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.720 0.280 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.720 0.280 0.000
S00.8 Superficial injury of other parts of head
0.719 0.281 0.000
T24 Burn and corrosion of hip and lower limb, except ankle and foot
0.718 0.282 0.000
H33.3 Retinal breaks without detachment
0.718 0.282 0.000
S43 Dislocation, sprain and strain of joints and ligaments of shoulder girdle
0.718 0.282 0.000
T21 Burn and corrosion of trunk
0.718 0.282 0.000
T33-T35 Frostbite
0.717 0.283 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.717 0.283 0.000
T00-T07 Injuries involving multiple body regions
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.717 0.283 0.000
G40.5 Special epileptic syndromes
0.717 0.283 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.717 0.283 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.717 0.283 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.717 0.283 0.000
G41 Status epilepticus
0.717 0.283 0.000
Q07.0 Arnold-Chiari syndrome
0.717 0.283 0.000
S80.9 Superficial injury of lower leg, unspecified
0.716 0.284 0.000
H17 Corneal scars and opacities
0.716 0.284 0.000
H35.8 Other specified retinal disorders
0.716 0.284 0.000
I51 Complications and ill-defined descriptions of heart disease
0.715 0.285 0.000
R46 Symptoms and signs involving appearance and behaviour
0.715 0.285 0.000
H43-H45 Disorders of vitreous body and globe
0.715 0.285 0.000
F90-F98 Behavioural and emotional disorders with onset usually occurring in childhood and adolescence
0.714 0.286 0.000
F70-F79 Mental retardation
0.714 0.286 0.000
G93.9 Disorder of brain, unspecified
0.714 0.286 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.713 0.287 0.000
R45.8 Other symptoms and signs involving emotional state
0.712 0.288 0.000
Q65-Q79 Congenital malformations and deformations of the musculoskeletal system
0.711 0.288 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.711 0.289 0.000
I77.1 Stricture of artery
0.710 0.290 0.000
S42 Fracture of shoulder and upper arm
0.710 0.290 0.000
I00-I02 Acute rheumatic fever
0.708 0.292 0.000
I79 Disorders of arteries, arterioles and capillaries in diseases classified elsewhere
0.708 0.292 0.000
H18.5 Hereditary corneal dystrophies
0.708 0.292 0.000
T98 Sequelae of other and unspecified effects of external causes
0.707 0.292 0.000
I77.8 Other specified disorders of arteries and arterioles
0.707 0.293 0.000
R04.0 Epistaxis
0.707 0.293 0.000
H32 Chorioretinal disorders in diseases classified elsewhere
0.706 0.293 0.000
H30 Chorioretinal inflammation
0.706 0.293 0.000
G90 Disorders of autonomic nervous system
0.706 0.294 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.705 0.295 0.000
S10 Superficial injury of neck
0.704 0.296 0.000
H35.5 Hereditary retinal dystrophy
0.703 0.297 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.703 0.297 0.000
G96.0 Cerebrospinal fluid leak
0.703 0.297 0.000
T20 Burn and corrosion of head and neck
0.702 0.298 0.000
T63 Toxic effect of contact with venomous animals
0.702 0.298 0.000
R45.1 Restlessness and agitation
0.702 0.298 0.000
F20 Schizophrenia
0.701 0.299 0.000
G97.8 Other postprocedural disorders of nervous system
0.700 0.300 0.000
H49-H52 Disorders of ocular muscles, binocular movement, accommodation and refraction
0.699 0.301 0.000
T66-T78 Other and unspecified effects of external causes
0.699 0.301 0.000
T45 Poisoning by primarily systemic and haematological agents, not elsewhere classified
0.699 0.301 0.000
R43 Disturbances of smell and taste
0.698 0.301 0.000
A80-A89 Viral infections of the central nervous system
0.698 0.302 0.000
F19 Mental and behavioural disorders due to multiple drug use and use of other psychoactive substances
0.698 0.302 0.000
F18 Mental and behavioural disorders due to use of volatile solvents
0.698 0.302 0.000
F16 Mental and behavioural disorders due to use of hallucinogens
0.698 0.302 0.000
F15 Mental and behavioural disorders due to use of other stimulants, including caffeine
0.698 0.302 0.000
F14 Mental and behavioural disorders due to use of cocaine
0.698 0.302 0.000
F11 Mental and behavioural disorders due to use of opioids
0.698 0.302 0.000
G94 Other disorders of brain in diseases classified elsewhere
0.697 0.303 0.000
G98 Other disorders of nervous system, not elsewhere classified
0.697 0.303 0.000
G92 Toxic encephalopathy
0.697 0.303 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.697 0.303 0.000
B15 Acute hepatitis A
0.696 0.303 0.000
S62.3 Fracture of other metacarpal bone
0.696 0.304 0.000
H33.2 Serous retinal detachment
0.696 0.304 0.000
I70 Atherosclerosis
0.695 0.305 0.000
G47.8 Other sleep disorders
0.695 0.305 0.000
R40.2 Coma, unspecified
0.695 0.305 0.000
H21 Other disorders of iris and ciliary body
0.693 0.307 0.000
F12 Mental and behavioural disorders due to use of cannabinoids
0.691 0.308 0.000
F10.9 Unspecified mental and behavioural disorder
0.691 0.309 0.000
F10.8 Other mental and behavioural disorders
0.691 0.309 0.000
F10.7 Residual and late-onset psychotic disorder
0.691 0.309 0.000
F10.6 Amnesic syndrome
0.691 0.309 0.000
T47 Poisoning by agents primarily affecting gastro-intestinal system
0.691 0.309 0.000
I73.8 Other specified peripheral vascular diseases
0.691 0.309 0.000
I73.1 Thromboangiitis obliterans [Buerger]
0.691 0.309 0.000
S08 Traumatic amputation of part of head
0.690 0.309 0.000
S07 Crushing injury of head
0.690 0.309 0.000
S04 Injury of cranial nerves
0.690 0.309 0.000
S03 Dislocation, sprain and strain of joints and ligaments of head
0.690 0.309 0.000
R25 Abnormal involuntary movements
0.690 0.310 0.000
I46 Cardiac arrest
0.690 0.310 0.000
Y52.4 Angiotensin-converting-enzyme inhibitors
0.688 0.312 0.000
R39.2 Extrarenal uraemia
0.688 0.312 0.000
R39.0 Extravasation of urine
0.688 0.312 0.000
R36 Urethral discharge
0.687 0.313 0.000
F07 Personality and behavioural disorders due to brain disease, damage and dysfunction
0.687 0.313 0.000
F02 Dementia in other diseases classified elsewhere
0.687 0.313 0.000
F09 Unspecified organic or symptomatic mental disorder
0.687 0.313 0.000
F04 Organic amnesic syndrome, not induced by alcohol and other psychoactive substances
0.687 0.313 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.686 0.314 0.000
F00.9 Dementia in Alzheimer's disease, unspecified
0.685 0.314 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.684 0.316 0.000
Chapter VIII Diseases of the ear and mastoid process
0.684 0.316 0.000
X50-X57 Overexertion, travel and privation
0.684 0.316 0.000
T82.2 Mechanical complication of coronary artery bypass and valve grafts
0.684 0.316 0.000
R30 Pain associated with micturition
0.684 0.316 0.000
S40.9 Superficial injury of shoulder and upper arm, unspecified
0.683 0.317 0.000
T65 Toxic effect of other and unspecified substances
0.683 0.317 0.000
T62 Toxic effect of other noxious substances eaten as food
0.683 0.317 0.000
T61 Toxic effect of noxious substances eaten as seafood
0.683 0.317 0.000
T60 Toxic effect of pesticides
0.683 0.317 0.000
T59 Toxic effect of other gases, fumes and vapours
0.683 0.317 0.000
T57 Toxic effect of other inorganic substances
0.683 0.317 0.000
T56 Toxic effect of metals
0.683 0.317 0.000
T54 Toxic effect of corrosive substances
0.683 0.317 0.000
T53 Toxic effect of halogen derivatives of aliphatic and aromatic hydrocarbone
0.683 0.317 0.000
T52 Toxic effect of organic solvents
0.683 0.317 0.000
T64 Toxic effect of aflatoxin and other mycotoxin food contaminants
0.683 0.317 0.000
T55 Toxic effect of soaps and detergents
0.683 0.317 0.000
F60-F69 Disorders of adult personality and behaviour
0.683 0.317 0.000
F10.2 Dependence syndrome
0.682 0.318 0.000
S00.5 Superficial injury of lip and oral cavity
0.682 0.318 0.000
Q90-Q99 Chromosomal abnormalities, not elsewhere classified
0.681 0.318 0.000
Q80-Q89 Other congenital malformations
0.681 0.318 0.000
Q35-Q37 Cleft lip and cleft palate
0.681 0.318 0.000
Q30-Q34 Congenital malformations of the respiratory system
0.681 0.318 0.000
Q10-Q18 Congenital malformations of eye, ear, face and neck
0.681 0.318 0.000
G93.1 Anoxic brain damage, not elsewhere classified
0.681 0.319 0.000
R41.8 Other and unspecified symptoms and signs involving cognitive functions and awareness
0.681 0.319 0.000
G93.8 Other specified disorders of brain
0.681 0.319 0.000
G30.9 Alzheimer's disease, unspecified
0.680 0.320 0.000
I77.6 Arteritis, unspecified
0.680 0.320 0.000
H31.8 Other specified disorders of choroid
0.679 0.321 0.000
T82.9 Unspecified complication of cardiac and vascular prosthetic device, implant and graft
0.679 0.321 0.000
T82.6 Infection and inflammatory reaction due to cardiac valve prosthesis
0.679 0.321 0.000
T82.4 Mechanical complication of vascular dialysis catheter
0.679 0.321 0.000
T82.0 Mechanical complication of heart valve prosthesis
0.679 0.321 0.000
H22 Disorders of iris and ciliary body in diseases classified elsewhere
0.679 0.321 0.000
H19 Disorders of sclera and cornea in diseases classified elsewhere
0.679 0.321 0.000
H15 Disorders of sclera
0.679 0.321 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.678 0.322 0.000
T23.2 Burn of second degree of wrist and hand
0.678 0.322 0.000
S48 Traumatic amputation of shoulder and upper arm
0.677 0.323 0.000
S45 Injury of blood vessels at shoulder and upper arm level
0.677 0.323 0.000
S44 Injury of nerves at shoulder and upper arm level
0.677 0.323 0.000
S47 Crushing injury of shoulder and upper arm
0.677 0.323 0.000
S41.1 Open wound of upper arm
0.676 0.324 0.000
Y40.8 Other systemic antibiotics
0.676 0.324 0.000
S93 Dislocation, sprain and strain of joints and ligaments at ankle and foot level
0.676 0.324 0.000
G93.2 Benign intracranial hypertension
0.675 0.325 0.000
H57.1 Ocular pain
0.675 0.325 0.000
H58 Other disorders of eye and adnexa in diseases classified elsewhere
0.674 0.326 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.673 0.327 0.000
Q60-Q64 Congenital malformations of the urinary system
0.673 0.327 0.000
B25-B34 Other viral diseases
0.673 0.327 0.000
B35-B49 Mycoses
0.673 0.327 0.000
I72.9 Aneurysm of unspecified site
0.673 0.327 0.000
I72.6 Aneurysm and dissection of vertebral artery
0.673 0.327 0.000
I72.5 Aneurysm and dissection of other precerebral arteries
0.673 0.327 0.000
I72.2 Aneurysm of renal artery
0.673 0.327 0.000
I72.1 Aneurysm of artery of upper extremity
0.673 0.327 0.000
I72.0 Aneurysm of carotid artery
0.673 0.327 0.000
S05.0 Injury of conjunctiva and corneal abrasion without mention of foreign body
0.673 0.327 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.672 0.328 0.000
S46.0 Injury of tendon of the rotator cuff of shoulder
0.670 0.330 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.670 0.330 0.000
B65-B83 Helminthiases
0.670 0.330 0.000
B50-B64 Protozoal diseases
0.670 0.330 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.670 0.330 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.670 0.330 0.000
A75-A79 Rickettsioses
0.670 0.330 0.000
A70-A74 Other diseases caused by chlamydiae
0.670 0.330 0.000
A65-A69 Other spirochaetal diseases
0.670 0.330 0.000
A20-A28 Certain zoonotic bacterial diseases
0.670 0.330 0.000
A15-A19 Tuberculosis
0.670 0.330 0.000
V40-V49 Car occupant injured in transport accident
0.670 0.330 0.000
H53-H54 Visual disturbances and blindness
0.669 0.331 0.000
S22 Fracture of rib(s), sternum and thoracic spine
0.668 0.332 0.000
G47.4 Narcolepsy and cataplexy
0.667 0.333 0.000
G47.2 Disorders of the sleep-wake schedule
0.667 0.333 0.000
B99-B99 Other infectious diseases
0.667 0.333 0.000
F50-F59 Behavioural syndromes associated with physiological disturbances and physical factors
0.666 0.334 0.000
I51.8 Other ill-defined heart diseases
0.666 0.334 0.000
T86 Failure and rejection of transplanted organs and tissues
0.665 0.334 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.665 0.335 0.000
H18.4 Corneal degeneration
0.664 0.336 0.000
S80.8 Other superficial injuries of lower leg
0.664 0.336 0.000
R34 Anuria and oliguria
0.664 0.336 0.000
F01.9 Vascular dementia, unspecified
0.664 0.336 0.000
W00-W19 Falls
0.663 0.336 0.000
Q05 Spina bifida
0.663 0.337 0.000
G32 Other degenerative disorders of nervous system in diseases classified elsewhere
0.663 0.337 0.000
R29.6 Tendency to fall, not elsewhere classified
0.663 0.337 0.000
F13.2 Dependence syndrome
0.662 0.338 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.661 0.339 0.000
B19 Unspecified viral hepatitis
0.661 0.339 0.000
S56 Injury of muscle and tendon at forearm level
0.661 0.339 0.000
R44.3 Hallucinations, unspecified
0.661 0.339 0.000
X60-X84 Intentional self-harm
0.660 0.339 0.000
U82-U85 Resistance to antimicrobial and antineoplastic drugs
0.659 0.341 0.000
X20-X29 Contact with venomous animals and plants
0.658 0.342 0.000
T92 Sequelae of injuries of upper limb
0.658 0.342 0.000
H18.8 Other specified disorders of cornea
0.658 0.342 0.000
R41.2 Retrograde amnesia
0.658 0.342 0.000
H18.6 Keratoconus
0.658 0.342 0.000
A41 Other septicaemia
0.657 0.343 0.000
B18 Chronic viral hepatitis
0.657 0.343 0.000
B95.4 Other streptococcus as the cause of diseases classified to other chapters
0.657 0.343 0.000
H35.9 Retinal disorder, unspecified
0.656 0.343 0.000
H35.7 Separation of retinal layers
0.656 0.343 0.000
H35.1 Retinopathy of prematurity
0.656 0.343 0.000
H42 Glaucoma in diseases classified elsewhere
0.655 0.344 0.000
S12 Fracture of neck
0.655 0.345 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.655 0.345 0.000
Y35-Y36 Legal intervention and operations of war
0.654 0.346 0.000
Y10-Y34 Event of undetermined intent
0.654 0.346 0.000
Y00-Y09 Assault
0.654 0.346 0.000
X85-X99 Assault
0.654 0.346 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.654 0.346 0.000
X30-X39 Exposure to forces of nature
0.654 0.346 0.000
X10-X19 Contact with heat and hot substances
0.654 0.346 0.000
X00-X09 Exposure to smoke, fire and flames
0.654 0.346 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.654 0.346 0.000
W75-W84 Other accidental threats to breathing
0.654 0.346 0.000
W65-W74 Accidental drowning and submersion
0.654 0.346 0.000
W50-W64 Exposure to animate mechanical forces
0.654 0.346 0.000
V98-V99 Other and unspecified transport accidents
0.654 0.346 0.000
V95-V97 Air and space transport accidents
0.654 0.346 0.000
V90-V94 Water transport accidents
0.654 0.346 0.000
V70-V79 Bus occupant injured in transport accident
0.654 0.346 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.654 0.346 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.654 0.346 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.654 0.346 0.000
V01-V09 Pedestrian injured in transport accident
0.654 0.346 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.654 0.346 0.000
T18 Foreign body in alimentary tract
0.654 0.346 0.000
T25 Burn and corrosion of ankle and foot
0.654 0.346 0.000
T22 Burn and corrosion of shoulder and upper limb, except wrist and hand
0.654 0.346 0.000
Q50-Q56 Congenital malformations of genital organs
0.654 0.346 0.000
I78.0 Hereditary haemorrhagic telangiectasia
0.653 0.347 0.000
T44 Poisoning by drugs primarily affecting the autonomic nervous system
0.653 0.347 0.000
S68 Traumatic amputation of wrist and hand
0.652 0.348 0.000
S80.7 Multiple superficial injuries of lower leg
0.651 0.349 0.000
T51.8 Other alcohols
0.650 0.350 0.000
T51.3 Fusel oil
0.650 0.350 0.000
T51.2 2-Propanol
0.650 0.350 0.000
T51.1 Methanol
0.650 0.350 0.000
T46 Poisoning by agents primarily affecting the cardiovascular system
0.649 0.351 0.000
V80-V89 Other land transport accidents
0.649 0.351 0.000
Q27.3 Peripheral arteriovenous malformation
0.649 0.351 0.000
F05.8 Other delirium
0.649 0.351 0.000
F05.1 Delirium superimposed on dementia
0.649 0.351 0.000
F05.0 Delirium not superimposed on dementia, so described
0.649 0.351 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.647 0.353 0.000
F06 Other mental disorders due to brain damage and dysfunction and to physical disease
0.645 0.355 0.000
S62.30 Fracture of other metacarpal bone (closed)
0.645 0.355 0.000
S46.2 Injury of muscle and tendon of other parts of biceps
0.644 0.356 0.000
G93.7 Reye's syndrome
0.643 0.357 0.000
G93.5 Compression of brain
0.643 0.357 0.000
G93.0 Cerebral cysts
0.643 0.357 0.000
F43 Reaction to severe stress, and adjustment disorders
0.643 0.357 0.000
H47 Other disorders of optic [2nd] nerve and visual pathways
0.641 0.359 0.000
F03 Unspecified dementia
0.640 0.360 0.000
I71.3 Abdominal aortic aneurysm, ruptured
0.640 0.360 0.000
T84.5 Infection and inflammatory reaction due to internal joint prosthesis
0.639 0.361 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.638 0.362 0.000
S89 Other and unspecified injuries of lower leg
0.638 0.362 0.000
H33.4 Traction detachment of retina
0.638 0.362 0.000
H33.1 Retinoschisis and retinal cysts
0.638 0.362 0.000
I74 Arterial embolism and thrombosis
0.638 0.362 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.637 0.363 0.000
G97.1 Other reaction to spinal and lumbar puncture
0.636 0.364 0.000
G91.1 Obstructive hydrocephalus
0.636 0.364 0.000
H20.9 Iridocyclitis, unspecified
0.636 0.364 0.000
R41.1 Anterograde amnesia
0.635 0.365 0.000
T51.9 Alcohol, unspecified
0.635 0.365 0.000
G83 Other paralytic syndromes
0.635 0.365 0.000
S19 Other and unspecified injuries of neck
0.634 0.366 0.000
S06 Intracranial injury
0.634 0.366 0.000
T50 Poisoning by diuretics and other and unspecified drugs, medicaments and biological substances
0.634 0.366 0.000
B95.8 Unspecified staphylococcus as the cause of diseases classified to other chapters
0.634 0.366 0.000
T84.7 Infection and inflammatory reaction due to other internal orthopaedic prosthetic devices, implants and grafts
0.633 0.366 0.000
H34.2 Other retinal artery occlusions
0.633 0.367 0.000
T49 Poisoning by topical agents primarily affecting skin and mucous membrane and by ophthalmological, otorhinolarygological and dental drugs
0.633 0.367 0.000
T48 Poisoning by agents primarily acting on smooth and skeletal muscles and the respiratory system
0.633 0.367 0.000
T41 Poisoning by anaesthetics and therapeutic gases
0.633 0.367 0.000
T38 Poisoning by hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.633 0.367 0.000
T37 Poisoning by other systemic anti-infectives and antiparasitics
0.633 0.367 0.000
T36 Poisoning by systemic antibiotics
0.633 0.367 0.000
S69 Other and unspecified injuries of wrist and hand
0.632 0.368 0.000
S09.8 Other specified injuries of head
0.632 0.368 0.000
I73.0 Raynaud's syndrome
0.632 0.368 0.000
R40.0 Somnolence
0.631 0.368 0.000
R26 Abnormalities of gait and mobility
0.631 0.368 0.000
H18.9 Disorder of cornea, unspecified
0.631 0.369 0.000
G47.0 Disorders of initiating and maintaining sleep [insomnias]
0.631 0.369 0.000
S52 Fracture of forearm
0.631 0.369 0.000
T95 Sequelae of burns, corrosions and frostbite
0.630 0.370 0.000
T94 Sequelae of injuries involving multiple and unspecified body regions
0.630 0.370 0.000
T97 Sequelae of toxic effects of substances chiefly nonmedicinal as to source
0.630 0.370 0.000
T96 Sequelae of poisoning by drugs, medicaments and biological substances
0.630 0.370 0.000
Y52.2 Other antidysrhythmic drugs, not elsewhere classified
0.629 0.371 0.000
T43.0 Tricyclic and tetracyclic antidepressants
0.629 0.371 0.000
S32.7 Multiple fractures of lumbar spine and pelvis
0.628 0.372 0.000
Y59 Other and unspecified vaccines and biological substances
0.628 0.372 0.000
Y58 Bacterial vaccines
0.628 0.372 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.628 0.372 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.628 0.372 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.628 0.372 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.628 0.372 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.628 0.372 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.628 0.372 0.000
Y48 Anaesthetics and therapeutic gases
0.628 0.372 0.000
B95.3 Streptococcus pneumoniae as the cause of diseases classified to other chapters
0.627 0.373 0.000
H40.2 Primary angle-closure glaucoma
0.627 0.373 0.000
S62.5 Fracture of thumb
0.626 0.374 0.000
G47.9 Sleep disorder, unspecified
0.626 0.374 0.000
Y46.4 Iminostilbenes
0.626 0.374 0.000
S50 Superficial injury of forearm
0.626 0.374 0.000
S05.1 Contusion of eyeball and orbital tissues
0.626 0.374 0.000
T90.9 Sequelae of unspecified injury of head
0.626 0.374 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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