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Variant clusters
Hospitalization Episode Statistics (HES)
Genetic variants: 36,212
Diagnostic terms: × 19,155
Association results: = 693,640,860
Self-Reported Statistics (SRS)
Genetic variants: 28,458
Diagnostic terms: × 474
Association results: = 13,489,092
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Variant-specific associations

rs17272021
log Bayes Factor = 15.6568
Chromosome 21   position 47,491,937  (GRCh37) Explore rs17272021 on Ensembl!
Variant rs17272021 is part of Cluster X0106

Hospitalization Episode Statistics (HES)

Self-Reported Statistics (SRS)
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Results table
Term Risk
posterior probability
 No effect
posterior probability
 Protective
posterior probability
  
# Top node
1.000 0.000 0.000
Chapter XVIII Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
1.000 0.000 0.000
Chapter XIV Diseases of the genitourinary system
1.000 0.000 0.000
N17-N19 Renal failure
1.000 0.000 0.000
Chapter XIII Diseases of the musculoskeletal system and connective tissue
0.999 0.001 0.000
Chapter II Neoplasms
0.994 0.006 0.000
Chapter I Certain infectious and parasitic diseases
0.994 0.006 0.000
R10-R19 Symptoms and signs involving the digestive system and abdomen
0.993 0.007 0.000
R00-R09 Symptoms and signs involving the circulatory and respiratory systems
0.993 0.007 0.000
Chapter VI Diseases of the nervous system
0.993 0.007 0.000
Chapter XX External causes of morbidity and mortality
0.991 0.009 0.000
N18 Chronic renal failure
0.991 0.009 0.000
R00 Abnormalities of heart beat
0.983 0.017 0.000
N19 Unspecified renal failure
0.983 0.017 0.000
Y40-Y59 Drugs, medicaments and biological substances causing adverse effects in therapeutic use
0.976 0.024 0.000
R00.2 Palpitations
0.971 0.029 0.000
M50-M54 Other dorsopathies
0.964 0.036 0.000
G40-G47 Episodic and paroxysmal disorders
0.962 0.038 0.000
Chapter XIX Injury, poisoning and certain other consequences of external causes
0.957 0.043 0.000
N18.3 Chronic kidney disease, stage 3
0.952 0.048 0.000
Chapter XI Diseases of the digestive system
0.949 0.051 0.000
R20-R23 Symptoms and signs involving the skin and subcutaneous tissue
0.946 0.054 0.000
M05-M14 Inflammatory polyarthropathies
0.946 0.054 0.000
N17 Acute renal failure
0.945 0.055 0.000
M54 Dorsalgia
0.945 0.055 0.000
G40 Epilepsy
0.944 0.056 0.000
T80-T88 Complications of surgical and medical care, not elsewhere classified
0.937 0.063 0.000
C60-C63 Malignant neoplasms of male genital organs
0.925 0.075 0.000
A30-A49 Other bacterial diseases
0.925 0.075 0.000
D37-D48 Neoplasms of uncertain or unknown behaviour
0.923 0.077 0.000
R00.1 Bradycardia, unspecified
0.922 0.078 0.000
N10-N16 Renal tubulo-interstitial diseases
0.920 0.080 0.000
M15-M19 Arthrosis
0.911 0.089 0.000
G20-G26 Extrapyramidal and movement disorders
0.910 0.090 0.000
Y42 Hormones and their synthetic substitutes and antagonists, not elsewhere classified
0.908 0.092 0.000
K65-K67 Diseases of peritoneum
0.906 0.094 0.000
Y57 Other and unspecified drugs and medicaments
0.906 0.094 0.000
N17.9 Acute renal failure, unspecified
0.906 0.094 0.000
N18.9 Chronic renal failure, unspecified
0.902 0.098 0.000
K20-K31 Diseases of oesophagus, stomach and duodenum
0.902 0.098 0.000
K55-K64 Other diseases of intestines
0.899 0.101 0.000
M13 Other arthritis
0.898 0.102 0.000
R12 Heartburn
0.897 0.103 0.000
Chapter XV Pregnancy, childbirth and the puerperium
0.896 0.104 0.000
Chapter XXI Factors influencing health status and contact with health services
0.892 0.108 0.000
M17 Gonarthrosis [arthrosis of knee]
0.888 0.112 0.000
R01 Cardiac murmurs and other cardiac sounds
0.884 0.116 0.000
B25-B34 Other viral diseases
0.883 0.117 0.000
M17.9 Gonarthrosis, unspecified
0.879 0.121 0.000
K66 Other disorders of peritoneum
0.877 0.123 0.000
C61 Malignant neoplasm of prostate
0.877 0.123 0.000
M54.5 Low back pain
0.877 0.123 0.000
C81-C96 Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue
0.876 0.124 0.000
G40.9 Epilepsy, unspecified
0.876 0.124 0.000
K21 Gastro-oesophageal reflux disease
0.875 0.125 0.000
R05 Cough
0.874 0.126 0.000
C76-C80 Malignant neoplasms of ill-defined, secondary and unspecified sites
0.870 0.130 0.000
W20-W49 Exposure to inanimate mechanical forces
0.867 0.133 0.000
K22 Other diseases of oesophagus
0.866 0.134 0.000
Y90-Y98 Supplementary factors related to causes of morbidity and mortality classified elsewhere
0.865 0.135 0.000
R30-R39 Symptoms and signs involving the urinary system
0.864 0.136 0.000
K58 Irritable bowel syndrome
0.864 0.136 0.000
M45-M49 Spondylopathies
0.863 0.137 0.000
N13 Obstructive and reflux uropathy
0.860 0.140 0.000
R11 Nausea and vomiting
0.859 0.141 0.000
B35-B49 Mycoses
0.859 0.141 0.000
Y57.9 Drug or medicament, unspecified
0.857 0.143 0.000
C15-C26 Malignant neoplasms of digestive organs
0.856 0.144 0.000
R15 Faecal incontinence
0.855 0.145 0.000
R20 Disturbances of skin sensation
0.853 0.147 0.000
B95-B98 Bacterial, viral and other infectious agents
0.851 0.149 0.000
R22 Localised swelling, mass and lump of skin and subcutaneous tissue
0.850 0.150 0.000
Y42.7 Androgens and anabolic congeners
0.850 0.150 0.000
K66.0 Peritoneal adhesions
0.849 0.151 0.000
R17 Unspecified jaundice
0.849 0.151 0.000
R32 Unspecified urinary incontinence
0.846 0.154 0.000
T82 Complications of cardiac and vascular prosthetic devices, implants and grafts
0.846 0.154 0.000
R70-R79 Abnormal findings on examination of blood, without diagnosis
0.845 0.155 0.000
R06 Abnormalities of breathing
0.842 0.158 0.000
M13.9 Arthritis, unspecified
0.837 0.163 0.000
R14 Flatulence and related conditions
0.836 0.164 0.000
K21.9 Gastro-oesophageal reflux disease without oesophagitis
0.835 0.165 0.000
N25-N29 Other disorders of kidney and ureter
0.835 0.165 0.000
R13 Dysphagia
0.834 0.166 0.000
K58.9 Irritable bowel syndrome without diarrhoea
0.833 0.167 0.000
G20 Parkinson's disease
0.831 0.169 0.000
Chapter III Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.830 0.170 0.000
B50-B64 Protozoal diseases
0.828 0.171 0.000
N18.4 Chronic kidney disease, stage 4
0.828 0.172 0.000
T84 Complications of internal orthopaedic prosthetic devices, implants and grafts
0.827 0.173 0.000
N60-N64 Disorders of breast
0.825 0.175 0.000
G70-G73 Diseases of myoneural junction and muscle
0.821 0.179 0.000
O60-O75 Complications of labour and delivery
0.821 0.179 0.000
M54.56 Low back pain (Lumbar region)
0.819 0.181 0.000
A41 Other septicaemia
0.818 0.182 0.000
Z40-Z54 Persons encountering health services for specific procedures and health care
0.814 0.186 0.000
M65-M68 Disorders of synovium and tendon
0.814 0.186 0.000
N20-N23 Urolithiasis
0.814 0.186 0.000
R18 Ascites
0.813 0.187 0.000
K22.8 Other specified diseases of oesophagus
0.811 0.189 0.000
K59 Other functional intestinal disorders
0.810 0.190 0.000
D47 Other neoplasms of uncertain or unknown behaviour of lymphoid, haematopoietic and related tissue
0.809 0.191 0.000
R01.1 Cardiac murmur, unspecified
0.805 0.195 0.000
M86-M90 Other osteopathies
0.804 0.195 0.000
C64-C68 Malignant neoplasms of urinary tract
0.804 0.196 0.000
S30-S39 Injuries to the abdomen, lower back, lumbar spine and pelvis
0.804 0.196 0.000
A49 Bacterial infection of unspecified site
0.803 0.197 0.000
G40.6 Grand mal seizures, unspecified (with or without petit mal)
0.802 0.198 0.000
B95 Streptococcus and staphylococcus as the cause of diseases classified to other chapters
0.801 0.199 0.000
T83 Complications of genito-urinary prosthetic devices, implants and grafts
0.801 0.199 0.000
G40.2 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with complex partial seizures
0.800 0.200 0.000
G90-G99 Other disorders of the nervous system
0.798 0.202 0.000
K25 Gastric ulcer
0.794 0.206 0.000
N13.3 Other and unspecified hydronephrosis
0.792 0.208 0.000
R25-R29 Symptoms and signs involving the nervous and musculoskeletal systems
0.792 0.208 0.000
R09 Other symptoms and signs involving the circulatory and respiratory systems
0.789 0.211 0.000
D00-D09 In situ neoplasms
0.788 0.212 0.000
M47 Spondylosis
0.786 0.214 0.000
Y52 Agents primarily affecting the cardiovascular system
0.786 0.214 0.000
Z00-Z13 Persons encountering health services for examination and investigation
0.786 0.214 0.000
C45-C49 Malignant neoplasms of mesothelial and soft tissue
0.786 0.214 0.000
R90-R94 Abnormal findings on diagnostic imaging and in function studies, without diagnosis
0.784 0.215 0.000
B00-B09 Viral infections characterized by skin and mucous membrane lesions
0.781 0.219 0.000
D41 Neoplasm of uncertain or unknown behaviour of urinary organs
0.777 0.223 0.000
M54.2 Cervicalgia
0.777 0.223 0.000
K70-K77 Diseases of liver
0.775 0.225 0.000
T86 Failure and rejection of transplanted organs and tissues
0.775 0.225 0.000
Y95 Nosocomial condition
0.775 0.225 0.000
Z13.0 Special screening examination for diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
0.774 0.226 0.000
Z13 Special screening examination for other diseases and disorders
0.774 0.226 0.000
K22.1 Ulcer of oesophagus
0.774 0.226 0.000
C97-C97 Malignant neoplasms of independent (primary) multiple sites
0.773 0.227 0.000
N00-N08 Glomerular diseases
0.772 0.228 0.000
R80-R82 Abnormal findings on examination of urine, without diagnosis
0.771 0.229 0.000
C00-C14 Malignant neoplasms of lip, oral cavity and pharynx
0.770 0.230 0.000
G40.3 Generalised idiopathic epilepsy and epileptic syndromes
0.768 0.231 0.000
M54.6 Pain in thoracic spine
0.768 0.232 0.000
G44 Other headache syndromes
0.768 0.232 0.000
S10-S19 Injuries to the neck
0.767 0.233 0.000
M80-M85 Disorders of bone density and structure
0.767 0.233 0.000
C78 Secondary malignant neoplasm of respiratory and digestive organs
0.767 0.233 0.000
Z45 Adjustment and management of implanted device
0.765 0.235 0.000
B34 Viral infection of unspecified site
0.765 0.235 0.000
T82.7 Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
0.765 0.235 0.000
K55 Vascular disorders of intestine
0.765 0.235 0.000
M13.99 Arthritis, unspecified (Site unspecified)
0.764 0.236 0.000
R20.8 Other and unspecified disturbances of skin sensation
0.764 0.236 0.000
R06.5 Mouth breathing
0.764 0.236 0.000
B37 Candidiasis
0.762 0.238 0.000
N99-N99 Other disorders of the genitourinary system
0.761 0.239 0.000
T29-T32 Burns and corrosions of multiple and unspecified body regions
0.760 0.240 0.000
X40-X49 Accidental poisoning by and exposure to noxious substances
0.760 0.240 0.000
N18.5 Chronic kidney disease, stage 5
0.760 0.240 0.000
M54.3 Sciatica
0.760 0.240 0.000
M60-M63 Disorders of muscles
0.759 0.240 0.000
M54.1 Radiculopathy
0.757 0.243 0.000
K21.0 Gastro-oesophageal reflux disease with oesophagitis
0.756 0.244 0.000
M13.0 Polyarthritis, unspecified
0.755 0.245 0.000
Chapter XVII Congenital malformations, deformations and chromosomal abnormalities
0.754 0.246 0.000
Y54 Agents primarily affecting water-balance and mineral and uric acid metabolism
0.754 0.246 0.000
Chapter IX Diseases of the circulatory system
0.752 0.248 0.000
Y45 Analgesics, antipyretics and anti-inflammatory drugs
0.751 0.249 0.000
C69-C72 Malignant neoplasms of eye, brain and other parts of central nervous system
0.749 0.251 0.000
R79 Other abnormal findings of blood chemistry
0.749 0.251 0.000
Y85-Y89 Sequelae of external causes of morbidity and mortality
0.747 0.253 0.000
N10 Acute tubulo-interstitial nephritis
0.746 0.254 0.000
M54.57 Low back pain (Lumbosacral region)
0.746 0.254 0.000
A41.9 Septicaemia, unspecified
0.742 0.258 0.000
S90-S99 Injuries to the ankle and foot
0.742 0.258 0.000
G35-G37 Demyelinating diseases of the central nervous system
0.740 0.260 0.000
R03 Abnormal blood-pressure reading, without diagnosis
0.739 0.260 0.000
Y60-Y69 Misadventures to patients during surgical and medical care
0.739 0.261 0.000
R93 Abnormal findings on diagnostic imaging of other body structures
0.737 0.263 0.000
K25.9 Unspecified as acute or chronic, without haemorrhage or perforation
0.736 0.264 0.000
B95.7 Other staphylococcus as the cause of diseases classified to other chapters
0.733 0.267 0.000
N23 Unspecified renal colic
0.733 0.267 0.000
Chapter XXII Codes for special purposes
0.732 0.268 0.000
S50-S59 Injuries to the elbow and forearm
0.732 0.268 0.000
Z48 Other surgical follow-up care
0.731 0.269 0.000
C73-C75 Malignant neoplasms of thyroid and other endocrine glands
0.731 0.269 0.000
C91 Lymphoid leukaemia
0.730 0.270 0.000
T80 Complications following infusion, transfusion and therapeutic injection
0.728 0.272 0.000
D47.2 Monoclonal gammopathy
0.728 0.272 0.000
K35-K38 Diseases of appendix
0.727 0.273 0.000
Chapter X Diseases of the respiratory system
0.726 0.274 0.000
D70-D77 Other diseases of blood and blood-forming organs
0.725 0.275 0.000
O20-O29 Other maternal disorders predominantly related to pregnancy
0.724 0.276 0.000
C25 Malignant neoplasm of pancreas
0.724 0.276 0.000
M06 Other rheumatoid arthritis
0.724 0.276 0.000
D48 Neoplasm of uncertain or unknown behaviour of other and unspecified sites
0.722 0.278 0.000
B95.6 Staphylococcus aureus as the cause of diseases classified to other chapters
0.722 0.278 0.000
T84.1 Mechanical complication of internal fixation device of bones of limb
0.722 0.278 0.000
R50-R69 General symptoms and signs
0.720 0.280 0.000
D37 Neoplasm of uncertain or unknown behaviour of oral cavity and digestive organs
0.718 0.281 0.000
R47-R49 Symptoms and signs involving speech and voice
0.718 0.282 0.000
R10 Abdominal and pelvic pain
0.717 0.282 0.000
R95-R99 Ill-defined and unknown causes of mortality
0.717 0.283 0.000
Chapter XVI Certain conditions originating in the perinatal period
0.717 0.283 0.000
B15-B19 Viral hepatitis
0.717 0.283 0.000
M95-M99 Other disorders of the musculoskeletal system and connective tissue
0.716 0.283 0.000
M91-M94 Chondropathies
0.716 0.283 0.000
M00-M03 Infectious arthropathies
0.716 0.283 0.000
M13.97 Arthritis, unspecified (Ankle and foot)
0.716 0.284 0.000
B25 Cytomegaloviral disease
0.715 0.285 0.000
W29 Contact with other powered hand tools and household machinery
0.714 0.286 0.000
O72 Postpartum haemorrhage
0.714 0.286 0.000
T90-T98 Sequelae of injuries, of poisoning and of other consequences of external causes
0.713 0.286 0.000
C40-C41 Malignant neoplasms of bone and articular cartilage
0.713 0.287 0.000
A50-A64 Infections with a predominantly sexual mode of transmission
0.713 0.287 0.000
B99-B99 Other infectious diseases
0.713 0.287 0.000
B90-B94 Sequelae of infectious and parasitic diseases
0.713 0.287 0.000
B85-B89 Pediculosis, acariasis and other infestations
0.713 0.287 0.000
B65-B83 Helminthiases
0.713 0.287 0.000
B20-B24 Human immunodeficiency virus [HIV] disease
0.713 0.287 0.000
A92-A99 Arthropod-borne viral fevers and viral haemorrhagic fevers
0.713 0.287 0.000
A80-A89 Viral infections of the central nervous system
0.713 0.287 0.000
A75-A79 Rickettsioses
0.713 0.287 0.000
A70-A74 Other diseases caused by chlamydiae
0.713 0.287 0.000
A65-A69 Other spirochaetal diseases
0.713 0.287 0.000
A20-A28 Certain zoonotic bacterial diseases
0.713 0.287 0.000
A15-A19 Tuberculosis
0.713 0.287 0.000
S30 Superficial injury of abdomen, lower back and pelvis
0.713 0.287 0.000
G47 Sleep disorders
0.712 0.288 0.000
G00-G09 Inflammatory diseases of the central nervous system
0.712 0.288 0.000
Y70-Y82 Medical devices associated with adverse incidents in diagnostic and therapeutic use
0.711 0.289 0.000
Y35-Y36 Legal intervention and operations of war
0.711 0.289 0.000
Y10-Y34 Event of undetermined intent
0.711 0.289 0.000
Y00-Y09 Assault
0.711 0.289 0.000
X85-X99 Assault
0.711 0.289 0.000
X58-X59 Accidental exposure to other and unspecified factors
0.711 0.289 0.000
X50-X57 Overexertion, travel and privation
0.711 0.289 0.000
X30-X39 Exposure to forces of nature
0.711 0.289 0.000
X20-X29 Contact with venomous animals and plants
0.711 0.289 0.000
X10-X19 Contact with heat and hot substances
0.711 0.289 0.000
X00-X09 Exposure to smoke, fire and flames
0.711 0.289 0.000
W85-W99 Exposure to electric current, radiation and extreme ambient air temperature and pressure
0.711 0.289 0.000
W75-W84 Other accidental threats to breathing
0.711 0.289 0.000
W65-W74 Accidental drowning and submersion
0.711 0.289 0.000
W50-W64 Exposure to animate mechanical forces
0.711 0.289 0.000
V98-V99 Other and unspecified transport accidents
0.711 0.289 0.000
V95-V97 Air and space transport accidents
0.711 0.289 0.000
V90-V94 Water transport accidents
0.711 0.289 0.000
V80-V89 Other land transport accidents
0.711 0.289 0.000
V70-V79 Bus occupant injured in transport accident
0.711 0.289 0.000
V60-V69 Occupant of heavy transport vehicle injured in transport accident
0.711 0.289 0.000
V50-V59 Occupant of pick-up truck or van injured in transport accident
0.711 0.289 0.000
V40-V49 Car occupant injured in transport accident
0.711 0.289 0.000
V30-V39 Occupant of three-wheeled motor vehicle injured in transport accident
0.711 0.289 0.000
V20-V29 Motorcycle rider injured in transport accident
0.711 0.289 0.000
V01-V09 Pedestrian injured in transport accident
0.711 0.289 0.000
N18.8 Other chronic renal failure
0.710 0.290 0.000
N18.2 Chronic kidney disease, stage 2
0.710 0.290 0.000
N18.1 Chronic kidney disease, stage 1
0.710 0.290 0.000
B59 Pneumocystosis
0.710 0.290 0.000
G24 Dystonia
0.707 0.293 0.000
G10-G14 Systemic atrophies primarily affecting the central nervous system
0.706 0.294 0.000
T08-T14 Injuries to unspecified part of trunk, limb or body region
0.706 0.294 0.000
N13.1 Hydronephrosis with ureteral stricture, not elsewhere classified
0.706 0.294 0.000
Z45.2 Adjustment and management of vascular access device
0.705 0.295 0.000
M47.8 Other spondylosis
0.703 0.297 0.000
Z42 Follow-up care involving plastic surgery
0.701 0.299 0.000
M10 Gout
0.700 0.300 0.000
M40-M43 Deforming dorsopathies
0.700 0.300 0.000
Y59 Other and unspecified vaccines and biological substances
0.700 0.300 0.000
Y58 Bacterial vaccines
0.700 0.300 0.000
Y56 Topical agents primarily affecting skin and mucous membrane and ophthalmological, otorhinolaryngological and dental drugs
0.700 0.300 0.000
Y55 Agents primarily acting on smooth and skeletal muscles and the respiratory system
0.700 0.300 0.000
Y53 Agents primarily affecting the gastro-intestinal system
0.700 0.300 0.000
Y50 Central nervous system stimulants, not elsewhere classified
0.700 0.300 0.000
Y49 Psychotropic drugs, not elsewhere classified
0.700 0.300 0.000
Y48 Anaesthetics and therapeutic gases
0.700 0.300 0.000
Y47 Sedatives, hypnotics and antianxiety drugs
0.700 0.300 0.000
Y46 Antiepileptics and anti-Parkinsonism drugs
0.700 0.300 0.000
Y41 Other systemic anti-infectives and antiparasitics
0.700 0.300 0.000
Z20-Z29 Persons with potential health hazards related to communicable diseases
0.699 0.301 0.000
R22.9 Localised swelling, mass and lump, unspecified
0.698 0.302 0.000
G70 Myasthenia gravis and other myoneural disorders
0.698 0.302 0.000
W21 Striking against or struck by sports equipment
0.698 0.302 0.000
M65 Synovitis and tenosynovitis
0.696 0.304 0.000
Z51 Other medical care
0.695 0.305 0.000
R22.1 Localised swelling, mass and lump, neck
0.695 0.305 0.000
N60 Benign mammary dysplasia
0.695 0.305 0.000
K66.8 Other specified disorders of peritoneum
0.694 0.306 0.000
M05 Seropositive rheumatoid arthritis
0.694 0.306 0.000
G80-G83 Cerebral palsy and other paralytic syndromes
0.694 0.306 0.000
G50-G59 Nerve, nerve root and plexus disorders
0.694 0.306 0.000
Z08 Follow-up examination after treatment for malignant neoplasm
0.693 0.307 0.000
K22.7 Barrett's oesophagus
0.692 0.308 0.000
M53 Other dorsopathies, not elsewhere classified
0.691 0.309 0.000
Y43 Primarily systemic agents
0.691 0.309 0.000
R10.3 Pain localised to other parts of lower abdomen
0.690 0.310 0.000
G46 Vascular syndromes of brain in cerebrovascular diseases
0.690 0.310 0.000
G41 Status epilepticus
0.690 0.310 0.000
Y42.5 Other oestrogens and progestogens
0.690 0.310 0.000
K76 Other diseases of liver
0.689 0.311 0.000
O30-O48 Maternal care related to the fetus and amniotic cavity and possible delivery problems
0.689 0.311 0.000
R83-R89 Abnormal findings on examination of other body fluids, substances and tissues, without diagnosis
0.687 0.313 0.000
A49.0 Staphylococcal infection, unspecified
0.686 0.314 0.000
C82 Follicular [nodular] non-Hodgkin's lymphoma
0.686 0.314 0.000
T84.8 Other complications of internal orthopaedic prosthetic devices, implants and grafts
0.686 0.314 0.000
T79-T79 Certain early complications of trauma
0.686 0.314 0.000
T33-T35 Frostbite
0.686 0.314 0.000
T26-T28 Burns and corrosions confined to eye and internal organs
0.686 0.314 0.000
T20-T25 Burns and corrosions of external body surface, specified by site
0.686 0.314 0.000
T15-T19 Effects of foreign body entering through natural orifice
0.686 0.314 0.000
T00-T07 Injuries involving multiple body regions
0.686 0.314 0.000
R60 Oedema, not elsewhere classified
0.686 0.314 0.000
M07 Psoriatic and enteropathic arthropathies
0.685 0.315 0.000
R16 Hepatomegaly and splenomegaly, not elsewhere classified
0.684 0.315 0.000
S80-S89 Injuries to the knee and lower leg
0.684 0.315 0.000
G30-G32 Other degenerative diseases of the nervous system
0.684 0.315 0.000
K59.8 Other specified functional intestinal disorders
0.684 0.316 0.000
Chapter VIII Diseases of the ear and mastoid process
0.682 0.318 0.000
G60-G64 Polyneuropathies and other disorders of the peripheral nervous system
0.682 0.318 0.000
R93.3 Abnormal findings on diagnostic imaging of other parts of digestive tract
0.681 0.319 0.000
R22.4 Localised swelling, mass and lump, lower limb
0.680 0.319 0.000
K56 Paralytic ileus and intestinal obstruction without hernia
0.680 0.320 0.000
B34.9 Viral infection, unspecified
0.680 0.320 0.000
R09.2 Respiratory arrest
0.680 0.320 0.000
C92 Myeloid leukaemia
0.680 0.320 0.000
D09 Carcinoma in situ of other and unspecified sites
0.679 0.320 0.000
N18.0 End-stage renal disease
0.679 0.321 0.000
R23 Other skin changes
0.678 0.322 0.000
M14 Arthropathies in other diseases classified elsewhere
0.678 0.322 0.000
M12 Other specific arthropathies
0.678 0.322 0.000
M09 Juvenile arthritis in diseases classified elsewhere
0.678 0.322 0.000
M08 Juvenile arthritis
0.678 0.322 0.000
K57 Diverticular disease of intestine
0.678 0.322 0.000
M51 Other intervertebral disk disorders
0.678 0.322 0.000
M54.9 Dorsalgia, unspecified
0.678 0.322 0.000
N17.8 Other acute renal failure
0.677 0.322 0.000
N17.2 Acute renal failure with medullary necrosis
0.677 0.322 0.000
N17.1 Acute renal failure with acute cortical necrosis
0.677 0.322 0.000
N17.0 Acute renal failure with tubular necrosis
0.677 0.322 0.000
M54.8 Other dorsalgia
0.677 0.323 0.000
M54.4 Lumbago with sciatica
0.677 0.323 0.000
M54.0 Panniculitis affecting regions of neck and back
0.677 0.323 0.000
G40.8 Other epilepsy
0.677 0.323 0.000
G40.7 Petit mal, unspecified, without grand mal seizures
0.677 0.323 0.000
G40.5 Special epileptic syndromes
0.677 0.323 0.000
G40.4 Other generalised epilepsy and epileptic syndromes
0.677 0.323 0.000
G40.1 Localisation-related (focal) (partial) symptomatic epilepsy and epileptic syndromes with simple partial seizures
0.677 0.323 0.000
G40.0 Localisation-related (focal) (partial) idiopathic epilepsy and epileptic syndromes with seizures of localised onset
0.677 0.323 0.000
C51-C58 Malignant neoplasms of female genital organs
0.676 0.324 0.000
I30-I52 Other forms of heart disease
0.676 0.324 0.000
V10-V19 Pedal cyclist injured in transport accident
0.676 0.324 0.000
Y40 Systemic antibiotics
0.676 0.324 0.000
Y44 Agents primarily affecting blood constituents
0.676 0.324 0.000
T81 Complications of procedures, not elsewhere classified
0.674 0.326 0.000
K58.0 Irritable bowel syndrome with diarrhoea
0.674 0.326 0.000
D41.4 Bladder
0.673 0.327 0.000
M46 Other inflammatory spondylopathies
0.673 0.327 0.000
D70 Agranulocytosis
0.673 0.327 0.000
R00.8 Other and unspecified abnormalities of heart beat
0.672 0.328 0.000
R20.2 Paraesthesia of skin
0.672 0.328 0.000
T87 Complications peculiar to reattachment and amputation
0.672 0.328 0.000
B37.8 Candidiasis of other sites
0.671 0.329 0.000
C78.0 Secondary malignant neoplasm of lung
0.671 0.329 0.000
T82.3 Mechanical complication of other vascular grafts
0.670 0.330 0.000
T83.1 Mechanical complication of other urinary devices and implants
0.669 0.331 0.000
N28 Other disorders of kidney and ureter, not elsewhere classified
0.669 0.331 0.000
N26 Unspecified contracted kidney
0.668 0.331 0.000
C30-C39 Malignant neoplasms of respiratory and intrathoracic organs
0.668 0.332 0.000
X60-X84 Intentional self-harm
0.668 0.332 0.000
R79.8 Other specified abnormal findings of blood chemistry
0.667 0.333 0.000
M13.91 Arthritis, unspecified (Shoulder region)
0.666 0.334 0.000
K55.9 Vascular disorder of intestine, unspecified
0.666 0.334 0.000
N13.4 Hydroureter
0.666 0.334 0.000
Z46 Fitting and adjustment of other devices
0.665 0.335 0.000
O69 Labour and delivery complicated by umbilical cord complications
0.664 0.336 0.000
C66 Malignant neoplasm of ureter
0.664 0.336 0.000
M54.58 Low back pain (Sacral and sacrococcygeal region)
0.664 0.336 0.000
G25 Other extrapyramidal and movement disorders
0.663 0.337 0.000
C63 Malignant neoplasm of other and unspecified male genital organs
0.663 0.337 0.000
C60 Malignant neoplasm of penis
0.663 0.337 0.000
R06.8 Other and unspecified abnormalities of breathing
0.663 0.337 0.000
A48 Other bacterial diseases, not elsewhere classified
0.663 0.337 0.000
A44 Bartonellosis
0.663 0.337 0.000
A43 Nocardiosis
0.663 0.337 0.000
A42 Actinomycosis
0.663 0.337 0.000
A40 Streptococcal septicaemia
0.663 0.337 0.000
A39 Meningococcal infection
0.663 0.337 0.000
A37 Whooping cough
0.663 0.337 0.000
A36 Diphtheria
0.663 0.337 0.000
A32 Listeriosis
0.663 0.337 0.000
A31 Infection due to other mycobacteria
0.663 0.337 0.000
A30 Leprosy [Hansen's disease]
0.663 0.337 0.000
A46 Erysipelas
0.663 0.337 0.000
A38 Scarlet fever
0.663 0.337 0.000
A35 Other tetanus
0.663 0.337 0.000
A34 Obstetrical tetanus
0.663 0.337 0.000
A33 Tetanus neonatorum
0.663 0.337 0.000
S60-S69 Injuries to the wrist and hand
0.663 0.337 0.000
D44 Neoplasm of uncertain or unknown behaviour of endocrine glands
0.661 0.338 0.000
D43 Neoplasm of uncertain or unknown behaviour of brain and central nervous system
0.661 0.338 0.000
D42 Neoplasm of uncertain or unknown behaviour of meninges
0.661 0.338 0.000
D40 Neoplasm of uncertain or unknown behaviour of male genital organs
0.661 0.338 0.000
D39 Neoplasm of uncertain or unknown behaviour of female genital organs
0.661 0.338 0.000
D38 Neoplasm of uncertain or unknown behaviour of middle ear and respiratory and intrathoracic organs
0.661 0.338 0.000
M17.0 Primary gonarthrosis, bilateral
0.661 0.339 0.000
O62 Abnormalities of forces of labour
0.661 0.339 0.000
S40-S49 Injuries to the shoulder and upper arm
0.661 0.339 0.000
N16 Renal tubulo-interstitial disorders in diseases classified elsewhere
0.660 0.340 0.000
N15 Other renal tubulo-interstitial diseases
0.660 0.340 0.000
N14 Drug- and heavy-metal-induced tubulo-interstitial and tubular conditions
0.660 0.340 0.000
N11 Chronic tubulo-interstitial nephritis
0.660 0.340 0.000
N30-N39 Other diseases of urinary system
0.660 0.340 0.000
C77 Secondary and unspecified malignant neoplasm of lymph nodes
0.659 0.341 0.000
T86.0 Bone-marrow transplant rejection
0.658 0.342 0.000
R06.2 Wheezing
0.658 0.342 0.000
M47.9 Spondylosis, unspecified
0.658 0.342 0.000
Chapter VII Diseases of the eye and adnexa
0.658 0.342 0.000
K59.9 Functional intestinal disorder, unspecified
0.658 0.342 0.000
K62 Other diseases of anus and rectum
0.658 0.342 0.000
D46 Myelodysplastic syndromes
0.657 0.342 0.000
C19 Malignant neoplasm of rectosigmoid junction
0.657 0.343 0.000
S20-S29 Injuries to the thorax
0.657 0.343 0.000
C22 Malignant neoplasm of liver and intrahepatic bile ducts
0.657 0.343 0.000
S70-S79 Injuries to the hip and thigh
0.656 0.344 0.000
D50-D53 Nutritional anaemias
0.655 0.345 0.000
W25 Contact with sharp glass
0.655 0.345 0.000
Y51 Drugs primarily affecting the autonomic nervous system
0.654 0.346 0.000
M20-M25 Other joint disorders
0.653 0.347 0.000
M15 Polyarthrosis
0.653 0.347 0.000
M13.00 Polyarthritis, unspecified (Multiple sites)
0.653 0.347 0.000
G23 Other degenerative diseases of basal ganglia
0.652 0.348 0.000
G21 Secondary Parkinsonism
0.652 0.348 0.000
G26 Extrapyramidal and movement disorders in diseases classified elsewhere
0.652 0.348 0.000
G22 Parkinsonism in diseases classified elsewhere
0.652 0.348 0.000
C83 Diffuse non-Hodgkin's lymphoma
0.652 0.348 0.000
C62 Malignant neoplasm of testis
0.651 0.349 0.000
O80-O84 Delivery
0.651 0.349 0.000
Y42.9 Other and unspecified hormone antagonists
0.651 0.349 0.000
Y42.8 Other and unspecified hormones and their synthetic substitutes
0.651 0.349 0.000
Y42.6 Antigonadotrophins, antioestrogens, antiandrogens, not elsewhere classified
0.651 0.349 0.000
Y42.4 Oral contraceptives
0.651 0.349 0.000
Y42.3 Insulin and oral hypoglycaemic [antidiabetic] drugs
0.651 0.349 0.000
Y42.2 Antithyroid drugs
0.651 0.349 0.000
Y42.1 Thyroid hormones and substitutes
0.651 0.349 0.000
Y42.0 Glucocorticoids and synthetic analogs
0.651 0.349 0.000
C20 Malignant neoplasm of rectum
0.651 0.349 0.000
B02 Zoster [herpes zoster]
0.650 0.349 0.000
K67 Disorders of peritoneum in infectious diseases classified elsewhere
0.650 0.350 0.000
Y57.8 Other drugs and medicaments
0.650 0.350 0.000
Y57.7 Vitamins, not elsewhere classified
0.650 0.350 0.000
Y57.6 Other diagnostic agents
0.650 0.350 0.000
Y57.5 X-ray contrast media
0.650 0.350 0.000
Y57.4 Pharmaceutical excipients
0.650 0.350 0.000
Y57.3 Alcohol deterrents
0.650 0.350 0.000
Y57.2 Antidotes and chelating agents, not elsewhere classified
0.650 0.350 0.000
Y57.1 Lipotropic drugs
0.650 0.350 0.000
Y57.0 Appetite depressants [anorectics]
0.650 0.350 0.000
R31 Unspecified haematuria
0.650 0.350 0.000
O10-O16 Oedema, proteinuria and hypertensive disorders in pregnancy, childbirth and the puerperium
0.650 0.350 0.000
M13.96 Arthritis, unspecified (Lower leg)
0.649 0.351 0.000
K59.3 Megacolon, not elsewhere classified
0.649 0.351 0.000
C85 Other and unspecified types of non-Hodgkin's lymphoma
0.648 0.352 0.000
K28 Gastrojejunal ulcer
0.646 0.353 0.000
K23 Disorders of oesophagus in diseases classified elsewhere
0.646 0.353 0.000
Z48.8 Other specified surgical follow-up care
0.646 0.354 0.000
T84.0 Mechanical complication of internal joint prosthesis
0.646 0.354 0.000
R22.2 Localised swelling, mass and lump, trunk
0.646 0.354 0.000
A41.1 Septicaemia due to other specified staphylococcus
0.645 0.355 0.000
J20-J22 Other acute lower respiratory infections
0.644 0.356 0.000
K64 Haemorrhoids and perianal venous thrombosis
0.644 0.356 0.000
M13.8 Other specified arthritis
0.644 0.356 0.000
M13.1 Monoarthritis, not elsewhere classified
0.644 0.356 0.000
R93.5 Abnormal findings on diagnostic imaging of other abdominal regions, including retroperitoneum
0.644 0.356 0.000
N61 Inflammatory disorders of breast
0.644 0.356 0.000
N13.0 Hydronephrosis with ureteropelvic junction obstruction
0.644 0.356 0.000
I26-I28 Pulmonary heart disease and diseases of pulmonary circulation
0.643 0.357 0.000
O85-O92 Complications predominantly related to the puerperium
0.642 0.358 0.000
N63 Unspecified lump in breast
0.642 0.358 0.000
O63 Long labour
0.642 0.358 0.000
M54.64 Pain in thoracic spine (Thoracic region)
0.641 0.358 0.000
T84.4 Mechanical complication of other internal orthopaedic devices, imnplants and grafts
0.640 0.360 0.000
M11 Other crystal arthropathies
0.640 0.360 0.000
R30 Pain associated with micturition
0.640 0.360 0.000
G99 Other disorders of nervous system in diseases classified elsewhere
0.640 0.360 0.000
N40-N51 Diseases of male genital organs
0.639 0.361 0.000
K22.6 Gastro-oesophageal laceration-haemorrhage syndrome
0.639 0.361 0.000
K65 Peritonitis
0.639 0.361 0.000
M65.9 Synovitis and tenosynovitis, unspecified
0.638 0.362 0.000
C45 Mesothelioma
0.637 0.363 0.000
M54.37 Sciatica (Lumbosacral region)
0.637 0.363 0.000
M17.5 Other secondary gonarthrosis
0.637 0.363 0.000
M17.4 Other secondary gonarthrosis, bilateral
0.637 0.363 0.000
M17.3 Other posttraumatic gonarthrosis
0.637 0.363 0.000
M17.2 Posttraumatic gonarthrosis, bilateral
0.637 0.363 0.000
N05 Unspecified nephritic syndrome
0.636 0.363 0.000
R21 Rash and other nonspecific skin eruption
0.636 0.364 0.000
K27 Peptic ulcer, site unspecified
0.636 0.364 0.000
C79 Secondary malignant neoplasm of other sites
0.636 0.364 0.000
I70-I79 Diseases of arteries, arterioles and capillaries
0.635 0.365 0.000
K57.9 Diverticular disease of intestine, part unspecified, without perforation or abscess
0.635 0.365 0.000
T88 Other complications of surgical and medical care, not elsewhere classified
0.634 0.366 0.000
R01.2 Other cardiac sounds
0.634 0.366 0.000
R01.0 Benign and innocent cardiac murmurs
0.634 0.366 0.000
O94-O99 Other obstetric conditions, not elsewhere classified
0.634 0.366 0.000
B33 Other viral diseases, not elsewhere classified
0.633 0.367 0.000

This table lists the top 500 terms ordered by p(effect).

The full results table can be downloaded from this page.

 

The TreeWAS Database is the result of research conducted at the Oxford Big Data Institute at the University of Oxford.

This research has been conducted using the UK Biobank Resource (application number 10625). This work uses data provided by patients and collected by the NHS as part of their care and support.

This research has been conducted with the support of the Wellcome Trust (100956/Z/13/Z and 090532/Z/09/Z and 100308/Z/12/Z), the Danish National Research Foundation, Takeda, the Medical Research Council (MC_UU_12010/3), the Oak Foundation (OCAY-15-520), the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre (BRC), the Wellcome Trust/Royal Society (204290/Z/16/Z) and the Li Ka Shing Foundation.

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